D:Progressive Bulbar Palsy

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pChart

Disease Term
Synonyms Bulbar Palsies, Bulbar Palsies Progressive, BULBAR PALSY, Bulbar Paralyses, Bulbar Paralysis, Childhood Progressive Bulbar Palsy, Fazio Londe Syndrome, Palsies Bulbar, Palsies Progressive Bulbar, Palsy Bulbar, PALSY PROGRESSIVE BULBAR
Documents 35
Hot Single Events 9
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Progressive Bulbar Palsy. They are ordered first by their relevance to Progressive Bulbar Palsy and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT211779 Binding of EIF4G1 and NTSR1 1 0.02 0 0 5.00
2 INT211781 Binding of NTSR1 and RDBP 1 0.00 0.42 0 5.00
3 INT211777 Binding of NTSR1 and PTBP1 1 0.03 0.82 0 5.00
4 INT264683 Binding of VAPB and ALS2 1 0.29 1.1 0 5.00
5 INT211780 Binding of AHSA1 and PLVAP 1 0.01 0 0 5.00
6 INT211776 Binding of PTBP2 and PLVAP 1 0.05 0.43 0 5.00
7 INT264679 IGFALS Positive_regulation of CTSC 1 0.02 1.68 0 5.00
8 INT264678 Binding of SETX and KRT20 1 0.00 2.17 0 5.00
9 INT264682 Binding of VAPB and SETX 1 0.28 1.09 0 5.00
10 INT211778 Binding of PCBP1 and PLVAP 1 0.07 0 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Progressive Bulbar Palsy. They are ordered first by their pain relevance and then by number of times they were reported in Progressive Bulbar Palsy. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT264689 Negative_regulation of IGFALS 10 0.33 12.58 0.45 100.00
2 INT163998 Gene_expression of CTSC 9 0.65 11.24 1.69 98.68
3 INT160251 Gene_expression of Myo5a 48 0.63 37.14 3.16 98.56
4 INT16013 Gene_expression of Rac1 52 0.75 23.79 1.21 98.52
5 INT6891 Binding of TTR 72 0.48 22.81 6.51 96.64
6 INT103164 Binding of UPF1 4 0.29 4.15 1.22 96.64
7 INT56342 Gene_expression of TTR 34 0.78 16.5 2.05 94.24
8 INT154283 Negative_regulation of FAM84B 1 0.07 0.69 0.32 91.72
9 INT101582 Negative_regulation of SNAP25 9 0.57 4.34 2.12 90.44
10 INT36309 Negative_regulation of DIO2 18 0.57 6.42 4.51 76.24
11 INT61680 Positive_regulation of PVR 23 0.60 23.27 3.86 71.40
12 INT82648 Positive_regulation of Gene_expression of GBA 1 0.50 2.77 0.08 69.28
13 INT8792 Gene_expression of GBA 20 0.78 14.73 1.98 68.36
14 INT3760 Positive_regulation of ALB 142 0.70 87.46 26.7 68.20
15 INT240278 Localization of IGFALS 11 0.53 9.44 0.29 67.52
16 INT8959 Binding of Gnb5 17 0.40 31.38 5.1 58.08
17 INT193582 Gene_expression of PVR 21 0.58 14 2.39 49.92
18 INT240280 Gene_expression of IGFALS 14 0.42 20.38 0.95 46.52
19 INT264686 Positive_regulation of Gene_expression of IGFALS 2 0.28 2.21 0.27 46.52
20 INT16012 Binding of Rac1 17 0.37 6.9 0.53 28.52
21 INT4960 Positive_regulation of CSF2 285 0.70 256.73 65.73 5.00
22 INT67981 Positive_regulation of CCL2 165 0.70 136.84 61.85 5.00
23 INT69437 Positive_regulation of ROS1 328 0.58 222.83 40.56 5.00
24 INT10248 Gene_expression of KRT20 436 0.78 231.96 32.88 5.00
25 INT11554 Negative_regulation of CSF2 129 0.59 108.55 29.44 5.00
26 INT15610 Localization of GOPC 223 0.65 68.26 28.7 5.00
27 INT48692 Binding of VEGFA 345 0.48 210.3 21.31 5.00
28 INT32515 Negative_regulation of B4GALNT1 82 0.43 28.1 17.46 5.00
29 INT11685 Regulation of CSF2 99 0.59 58.82 15.9 5.00
30 INT31990 Positive_regulation of SOD1 124 0.69 67.79 12.52 5.00
31 INT6511 Positive_regulation of AFP 76 0.70 70.15 7.28 5.00
32 INT38672 Binding of KRT20 69 0.39 48.01 6.31 5.00
33 INT179744 Negative_regulation of SLC1A2 16 0.45 12.32 6.14 5.00
34 INT68661 Positive_regulation of NTSR1 11 0.69 9.6 5.91 5.00
35 INT7083 Positive_regulation of HBM 35 0.66 20.96 4.3 5.00
36 INT98624 Regulation of Aqp4 27 0.62 30.76 3.77 5.00
37 INT191807 Gene_expression of CD24 75 0.78 53.92 3.34 5.00
38 INT8477 Negative_regulation of AFP 35 0.58 31.52 3.1 5.00
39 INT111263 Gene_expression of Gnb5 8 0.75 8.51 3 5.00
40 INT24443 Gene_expression of PSMD2 20 0.54 7.29 2.77 5.00
41 INT68781 Negative_regulation of TFAM 15 0.58 10.01 2.42 5.00
42 INT97453 Negative_regulation of MOCS1 25 0.04 13.4 2.4 5.00
43 INT68658 Gene_expression of NTSR1 17 0.77 7.88 2.32 5.00
44 INT134944 Gene_expression of MOCS1 37 0.06 10.76 2.17 5.00
45 INT122924 Binding of ipv 27 0.42 31.81 1.99 5.00
46 INT195817 Gene_expression of ipv 28 0.58 31.04 1.86 5.00
47 INT95226 Gene_expression of AHSA1 5 0.49 3.62 1.52 5.00
48 INT105569 Binding of IGFALS 13 0.25 17.31 1.36 5.00
49 INT137382 Negative_regulation of Gene_expression of KRT20 22 0.58 12.29 1.29 5.00
50 INT154098 Binding of NTSR1 3 0.47 1.18 1.28 5.00
51 INT28929 Negative_regulation of PVR 22 0.57 16.64 1.07 5.00
52 INT192785 Regulation of Myo5a 4 0.05 9.05 0.93 5.00
53 INT160799 Regulation of IGFALS 11 0.29 9.09 0.7 5.00
54 INT211782 Localization of Ambp 2 0.26 2.12 0.64 5.00
55 INT211808 Localization of NFKB2 4 0.19 4.17 0.58 5.00
56 INT240281 Positive_regulation of IGFALS 11 0.31 10.44 0.56 5.00
57 INT61972 Negative_regulation of TBP 5 0.32 3.56 0.53 5.00
58 INT211807 Binding of PTBP1 11 0.31 6.09 0.45 5.00
59 INT96520 Gene_expression of PRPH 5 0.75 2.55 0.39 5.00
60 INT115212 Gene_expression of PLVAP 2 0.30 1.1 0.38 5.00
61 INT206440 Binding of MOCS1 13 0.01 3.76 0.35 5.00
62 INT181781 Positive_regulation of FOSB 6 0.39 4.77 0.34 5.00
63 INT134943 Localization of MOCS1 7 0.07 4.23 0.34 5.00
64 INT211814 Transcription of polymerase 3 0.04 0.97 0.33 5.00
65 INT264684 Regulation of Gene_expression of TARDBP 1 0.41 4.21 0.31 5.00
66 INT264685 Gene_expression of TARDBP 4 0.61 8.8 0.31 5.00
67 INT264687 Binding of TARDBP 1 0.33 4.14 0.31 5.00
68 INT241803 Positive_regulation of GBA 6 0.70 2.41 0.3 5.00
69 INT211815 Gene_expression of CSDE1 4 0.27 2.34 0.29 5.00
70 INT134946 Localization of GBA 3 0.75 2.49 0.24 5.00
71 INT116432 Positive_regulation of Positive_regulation of SOD1 3 0.40 3.88 0.2 5.00
72 INT285702 Negative_regulation of Tpmt 2 0.28 1.4 0.19 5.00
73 INT211839 Binding of EIF4E 8 0.36 0.79 0.18 5.00
74 INT206971 Positive_regulation of Localization of MOCS1 2 0.01 0.71 0.16 5.00
75 INT154448 Negative_regulation of FOSB 3 0.41 2.11 0.16 5.00
76 INT211827 Localization of PVR 3 0.61 1.33 0.13 5.00
77 INT186197 Gene_expression of SCARB2 7 0.40 2.93 0.13 5.00
78 INT114901 Binding of TBP 6 0.17 2.45 0.11 5.00
79 INT211821 Binding of PLXNC1 2 0.01 0.57 0.09 5.00
80 INT211806 Gene_expression of PLXNC1 4 0.63 2.95 0.07 5.00
81 INT211835 Binding of SRSF3 1 0.19 0.14 0.07 5.00
82 INT211809 Localization of NTSR1 1 0.10 0.63 0.07 5.00
83 INT186200 Negative_regulation of Gene_expression of SCARB2 2 0.22 1.02 0.04 5.00
84 INT211830 Binding of PVR 3 0.32 2.26 0.03 5.00
85 INT211829 Protein_catabolism of TBP 1 0.17 0.09 0 5.00
86 INT211820 Negative_regulation of PLVAP 1 0.17 0.8 0 5.00
87 INT211826 Binding of PCBP1 1 0.21 0 0 5.00
88 INT211840 Protein_catabolism of EIF4G1 1 0.35 0.13 0 5.00
89 INT211836 Binding of EIF4G1 1 0.12 0.07 0 5.00
90 INT211833 Gene_expression of PCBP1 1 0.13 0 0 5.00
91 INT211817 Protein_catabolism of ATP5G3 1 0.07 0.05 0 5.00
92 INT211823 Binding of CSDE1 1 0.15 0.71 0 5.00
93 INT211824 Positive_regulation of Gene_expression of PLXNC1 1 0.01 0.07 0 5.00
94 INT352686 Positive_regulation of Positive_regulation of FOSB 1 0.03 0.53 0 5.00
95 INT211834 Localization of PXDN 1 0.19 0.06 0 5.00
96 INT211831 Binding of PLVAP 1 0.14 0.73 0 5.00
97 INT69480 Protein_catabolism of GBA 2 0.89 0.38 0 5.00
98 INT211812 Negative_regulation of PCBP1 1 0.19 0 0 5.00
99 INT298918 Binding of RILP 2 0.17 0.55 0 5.00
100 INT352684 Regulation of Binding of RILP 1 0.01 0.22 0 5.00
101 INT211825 Transcription of POLR3GL 1 0.03 0.42 0 5.00
102 INT211819 Positive_regulation of PLVAP 1 0.27 0.7 0 5.00
103 INT211832 Binding of EIF2A 1 0.12 0.08 0 5.00
104 INT211822 Transcription of PLVAP 1 0.21 0 0 5.00
105 INT211837 Negative_regulation of SRSF3 1 0.12 0.29 0 5.00
106 INT352685 Positive_regulation of Gene_expression of SCARB2 1 0.11 0.51 0 5.00
107 INT211818 Protein_catabolism of TFAM 1 0.01 0.09 0 5.00
108 INT211816 Negative_regulation of Gene_expression of CSDE1 1 0.17 0.35 0 5.00
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