D:Prolymphocytic Leukemia

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pChart

Disease Term
Synonyms Leukemias Prolymphocytic, Prolymphocytic Leukemias
Documents 12
Hot Single Events 0
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Prolymphocytic Leukemia. They are ordered first by their relevance to Prolymphocytic Leukemia and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT193695 Il2 Positive_regulation of Ctla4 1 0.01 1.63 0.18 5.00
2 INT193693 Binding of Myd88 and Pain1 1 0.14 0.82 0.13 5.00
3 INT193697 Apaf1 Positive_regulation of CASP9 1 0.02 1.84 0.12 5.00
4 INT193691 Positive_regulation of Positive_regulation of Bcr 1 0.01 0.07 0.08 5.00
5 INT193692 IgG2a Positive_regulation of Bcr 1 0.02 0.07 0.08 5.00
6 INT193694 IgG2a Positive_regulation of Tlr9 1 0.05 0.07 0.08 5.00
7 INT193696 Binding of CD8A and Trav6-3 1 0.00 0.85 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Prolymphocytic Leukemia. They are ordered first by their pain relevance and then by number of times they were reported in Prolymphocytic Leukemia. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT28249 Positive_regulation of HLA-DRA 25 0.70 13.63 3.25 75.00
2 INT17417 Positive_regulation of Ighd 16 0.69 24.29 2.8 75.00
3 INT3400 Positive_regulation of pr 57 0.68 36.9 16.24 74.56
4 INT22112 Positive_regulation of Localization of TNF 164 0.70 115.66 52.18 55.72
5 INT6852 Localization of TNF 883 0.81 705.95 270.84 54.40
6 INT173975 Gene_expression of Cd52 5 0.28 5.63 0.21 26.32
7 INT182339 Gene_expression of Ms4a1 18 0.68 16.6 0.42 25.60
8 INT5058 Positive_regulation of IFNA1 356 0.70 245.75 60.52 18.80
9 INT63975 Positive_regulation of Il10 175 0.68 134.13 54.69 18.80
10 INT13186 Positive_regulation of Il4 113 0.68 71.22 31.4 18.80
11 INT11803 Positive_regulation of Il2 62 0.70 31.44 18.93 18.80
12 INT100938 Positive_regulation of Il13 47 0.69 42.11 14.36 18.80
13 INT97439 Positive_regulation of Il5 46 0.60 25.6 9.47 18.80
14 INT10795 Positive_regulation of CD59 9 0.36 2.11 2.52 11.04
15 INT134339 Positive_regulation of CD55 8 0.56 3.19 0.54 10.32
16 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 8.80
17 INT80220 Positive_regulation of Bcl2 71 0.58 57.73 7.86 5.12
18 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 5.00
19 INT867 Gene_expression of IFNA1 930 0.78 594.85 168.03 5.00
20 INT60694 Gene_expression of Il10 567 0.78 369.48 143.69 5.00
21 INT20374 Gene_expression of Il4 515 0.76 306.15 114.12 5.00
22 INT69440 Gene_expression of ROS1 752 0.78 477.64 103.83 5.00
23 INT77435 Positive_regulation of Nos2 343 0.70 208.49 91.43 5.00
24 INT3375 Gene_expression of IGHE 535 0.77 387.47 65.46 5.00
25 INT11807 Gene_expression of Il2 266 0.78 112 64.97 5.00
26 INT20375 Gene_expression of Hand1 213 0.60 148.51 54.53 5.00
27 INT19775 Localization of Il1 183 0.78 145.5 50.91 5.00
28 INT69437 Positive_regulation of ROS1 328 0.58 222.83 40.56 5.00
29 INT3987 Positive_regulation of IGHE 316 0.70 283.2 40.16 5.00
30 INT77307 Gene_expression of Bcl2 399 0.77 319.77 38 5.00
31 INT74563 Positive_regulation of Gene_expression of ROS1 258 0.61 168.18 34.08 5.00
32 INT10248 Gene_expression of KRT20 436 0.78 231.96 32.88 5.00
33 INT21900 Gene_expression of Mthfd1 150 0.75 69.47 27.03 5.00
34 INT17331 Positive_regulation of JUN 132 0.69 60.4 27.03 5.00
35 INT83797 Gene_expression of Bcl2l1 124 0.77 94.55 22.39 5.00
36 INT84732 Positive_regulation of Hand2 81 0.69 62.07 22 5.00
37 INT9220 Gene_expression of Ighg1 125 0.77 85.74 15.92 5.00
38 INT60197 Gene_expression of JUN 90 0.78 42.32 14.61 5.00
39 INT99780 Positive_regulation of Cxcl10 43 0.69 39.67 13.27 5.00
40 INT81629 Positive_regulation of Fas 58 0.70 59.63 12.94 5.00
41 INT31990 Positive_regulation of SOD1 124 0.69 67.79 12.52 5.00
42 INT112003 Localization of ROS1 94 0.73 66.32 12.16 5.00
43 INT81640 Positive_regulation of Gene_expression of Bcl2 106 0.69 84.58 11.63 5.00
44 INT58449 Binding of Mthfd1 47 0.47 22.02 10.29 5.00
45 INT10019 Binding of CD8A 57 0.36 31.49 10.08 5.00
46 INT3988 Positive_regulation of Gene_expression of IGHE 98 0.68 91.46 9.61 5.00
47 INT3846 Positive_regulation of GSR 60 0.50 35.16 9.37 5.00
48 INT846 Positive_regulation of B2M 42 0.70 29.78 8.06 5.00
49 INT193663 Binding of Pain1 9 0.36 8.84 8.04 5.00
50 INT77306 Negative_regulation of Gene_expression of Bcl2 46 0.58 38.05 7.71 5.00
51 INT99942 Positive_regulation of Fasl 37 0.68 32.61 6.92 5.00
52 INT160562 Localization of Cd4 49 0.71 27.58 6.78 5.00
53 INT17618 Gene_expression of B2M 36 0.66 16.39 6.68 5.00
54 INT38672 Binding of KRT20 69 0.39 48.01 6.31 5.00
55 INT53196 Binding of Cd4 44 0.47 27.28 5.85 5.00
56 INT84704 Positive_regulation of Nqo1 18 0.70 18.64 5.65 5.00
57 INT38671 Positive_regulation of KRT20 62 0.53 40.17 5.6 5.00
58 INT38670 Positive_regulation of Gene_expression of KRT20 68 0.69 23.25 5.55 5.00
59 INT59891 Positive_regulation of GSTK1 46 0.67 17.66 5.33 5.00
60 INT76313 Gene_expression of CD38 30 0.64 20.74 5.27 5.00
61 INT68244 Positive_regulation of Ighg1 60 0.61 48.86 5.01 5.00
62 INT188672 Positive_regulation of Tlr9 15 0.67 13.1 4.48 5.00
63 INT83794 Positive_regulation of Gene_expression of Bcl2l1 26 0.69 16.89 4.28 5.00
64 INT138698 Gene_expression of Txn1 15 0.77 11.71 4.24 5.00
65 INT57645 Gene_expression of GSTK1 54 0.62 21.05 4.2 5.00
66 INT89966 Negative_regulation of Fas 26 0.58 24.83 3.5 5.00
67 INT130295 Gene_expression of Abcg2 21 0.75 9.75 3.42 5.00
68 INT16969 Negative_regulation of CRS 28 0.37 14.77 3.35 5.00
69 INT81453 Positive_regulation of Gene_expression of JUN 18 0.50 9.39 3.23 5.00
70 INT157401 Gene_expression of Ctla4 21 0.65 15.43 3.2 5.00
71 INT140555 Positive_regulation of Localization of ROS1 29 0.55 23.82 3.14 5.00
72 INT93936 Gene_expression of Pgp 10 0.59 3.43 3.04 5.00
73 INT40315 Gene_expression of Abcc1 10 0.76 5.66 2.53 5.00
74 INT133766 Negative_regulation of Fasl 11 0.56 11.28 2.27 5.00
75 INT101641 Gene_expression of Mcl1 25 0.54 20.3 2.23 5.00
76 INT38674 Regulation of KRT20 32 0.44 19 2.15 5.00
77 INT188678 Binding of Tlr7 14 0.32 6.6 1.89 5.00
78 INT56925 Negative_regulation of TSC1 54 0.52 63.39 1.87 5.00
79 INT61913 Binding of IgG2a 10 0.47 5.04 1.64 5.00
80 INT60542 Positive_regulation of Gene_expression of GSTK1 11 0.39 6.21 1.13 5.00
81 INT19628 Regulation of Xdh 6 0.45 1.9 1.07 5.00
82 INT193069 Positive_regulation of Gene_expression of CD38 4 0.15 4.06 1.01 5.00
83 INT130297 Positive_regulation of Gene_expression of Abcc1 3 0.56 1.06 0.97 5.00
84 INT135260 Negative_regulation of Pgp 4 0.42 1.13 0.95 5.00
85 INT193666 Gene_expression of Gpr83 2 0.14 0.92 0.91 5.00
86 INT112694 Negative_regulation of Positive_regulation of Fas 5 0.42 4.3 0.89 5.00
87 INT135729 Gene_expression of Zap70 5 0.75 6.86 0.75 5.00
88 INT133323 Positive_regulation of Mod2 8 0.13 5.55 0.72 5.00
89 INT117416 Gene_expression of FAM20C 3 0.65 1.55 0.65 5.00
90 INT193665 Positive_regulation of Stat4 4 0.47 1.83 0.65 5.00
91 INT193672 Gene_expression of Prdx2 3 0.50 2.75 0.64 5.00
92 INT158329 Positive_regulation of Gene_expression of Mcl1 9 0.32 7.53 0.54 5.00
93 INT186290 Binding of Pvrl1 8 0.11 4.82 0.46 5.00
94 INT193674 Binding of Bcr 10 0.47 4.3 0.36 5.00
95 INT46843 Binding of Trf 10 0.47 3.45 0.35 5.00
96 INT67140 Regulation of Mod2 3 0.41 2.54 0.34 5.00
97 INT193669 Gene_expression of Pvrl1 13 0.22 6.4 0.33 5.00
98 INT193667 Regulation of Localization of Cd4 2 0.43 1.01 0.21 5.00
99 INT187883 Gene_expression of Mod2 8 0.18 4.59 0.15 5.00
100 INT351025 Positive_regulation of Gene_expression of Zap70 1 0.14 2.14 0.15 5.00
101 INT172476 Transcription of NFE2L2 7 0.69 2.47 0.11 5.00
102 INT193676 Positive_regulation of Gene_expression of Prdx2 2 0.06 1.31 0.09 5.00
103 INT193687 Gene_expression of TIMM8A 2 0.49 1.27 0.04 5.00
104 INT193686 Positive_regulation of Positive_regulation of GLRX2 1 0.04 0.79 0.04 5.00
105 INT193678 Regulation of Transcription of NFE2L2 1 0.06 0.69 0.04 5.00
106 INT193677 Positive_regulation of Gene_expression of TIMM8A 1 0.03 0.91 0.04 5.00
107 INT193685 Positive_regulation of GLRX2 2 0.24 1.11 0.04 5.00
108 INT193680 Negative_regulation of GLRX2 1 0.03 0.8 0.04 5.00
109 INT193675 Regulation of Gene_expression of Mod2 1 0.05 0.89 0.03 5.00
110 INT193688 Positive_regulation of Gene_expression of GLRX2 1 0.04 0.7 0.03 5.00
111 INT193683 Gene_expression of GLRX2 1 0.05 0.7 0.03 5.00
112 INT193671 Gene_expression of Txnrd2 1 0.01 1.02 0 5.00
113 INT279204 Binding of Cd52 1 0.13 0.69 0 5.00
114 INT193679 Positive_regulation of Gene_expression of FAM20C 1 0.49 1.18 0 5.00
115 INT193670 Regulation of Csda 1 0.60 0.54 0 5.00
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