D:Pseudarthrosis

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Disease Term
Synonyms Pseudarthroses, Pseudoarthroses, Pseudoarthrosis
Documents 701
Hot Single Events 22
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Pseudarthrosis. They are ordered first by their relevance to Pseudarthrosis and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT170992 Binding of FN1 and MMRN1 3 0.01 2.13 0.73 70.04
2 INT227928 Binding of MMRN1 and Lamb3 1 0.03 1.16 0.56 70.04
3 INT227911 Binding of VTN and MMRN1 1 0.01 1.16 0.56 70.04
4 INT227908 Binding of COL7A1 and MMRN1 1 0.00 1.11 0.53 70.04
5 INT191612 Nf1 Positive_regulation of ras 1 0.25 2.6 0.11 56.24
6 INT191614 Adcyap1 Positive_regulation of Rtcd1 1 0.01 0.93 0 33.32
7 INT227907 TNFRSF1B Regulation of TNF 1 0.01 0.41 0.36 14.08
8 INT227904 TNFRSF1A Regulation of TNF 1 0.01 0.41 0.36 14.08
9 INT148704 Binding of TNF and TNFRSF1A 5 0.44 3.3 2.09 5.00
10 INT191618 Binding of App and Nf1 1 0.35 3.77 1.65 5.00
11 INT61134 IL10 Negative_regulation of Gene_expression of IL1B 3 0.46 2.13 1.63 5.00
12 INT191610 Binding of App and Drd3 1 0.20 0.7 0.42 5.00
13 INT227906 IL10 Regulation of Gene_expression of IL1B 1 0.07 0.57 0.38 5.00
14 INT227909 IL10 Regulation of Gene_expression of TNF 1 0.21 0.57 0.38 5.00
15 INT191616 Binding of Cbln1 and Nf1 1 0.01 0.2 0.32 5.00
16 INT191620 Binding of Nf1 and Gopc 1 0.08 0.2 0.32 5.00
17 INT191611 Nf1 Regulation of ras 1 0.26 0.18 0.3 5.00
18 INT227910 TNF Positive_regulation of Gene_expression of IL10 1 0.22 0.68 0.29 5.00
19 INT227903 TNF Positive_regulation of Gene_expression of ADAMTS5 1 0.01 0.56 0.24 5.00
20 INT191619 Binding of App and Flna 1 0.04 0.18 0.24 5.00
21 INT227905 IL10 Positive_regulation of Gene_expression of TIMP1 1 0.01 0.48 0.22 5.00
22 INT326460 NR1I2 Regulation of Cyp4f18 1 0.01 0.72 0.18 5.00
23 INT191609 Binding of Drd3 and Flna 1 0.06 0.42 0.17 5.00
24 INT191615 Binding of Nf1 and Flna 1 0.08 0.53 0.17 5.00
25 INT191621 Binding of Drd3 and Nf1 1 0.32 0.53 0.17 5.00
26 INT239081 Binding of GH1 and MAS1 1 0.03 1.41 0.15 5.00
27 INT269788 Binding of FN1 and TGFB1 1 0.00 0.29 0.1 5.00
28 INT191617 Binding of Nf1 and Rtcd1 1 0.01 0.95 0.08 5.00
29 INT191613 Binding of Nf1 and Rasa1 1 0.06 0.88 0.03 5.00
30 INT239080 Binding of PPY and KAT2B 1 0.02 2.38 0 5.00
31 INT180836 Binding of CTD and NF1 1 0.15 0.2 0 5.00
32 INT274705 Binding of TXNRD1 and Dh 1 0.00 0 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Pseudarthrosis. They are ordered first by their pain relevance and then by number of times they were reported in Pseudarthrosis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT149703 Gene_expression of Insl3 1 0.40 2.27 1.02 98.92
2 INT68216 Binding of NF1 40 0.48 51.24 4.59 98.40
3 INT28647 Binding of CTD 13 0.31 14.2 1.5 98.16
4 INT3925 Negative_regulation of HLA-B 29 0.42 20.19 9.46 95.08
5 INT749 Gene_expression of HLA-B 341 0.75 224.12 77.37 94.44
6 INT2540 Negative_regulation of Calca 538 0.59 172.11 384.38 94.24
7 INT1108 Gene_expression of PPY 58 0.75 36.57 10.76 92.68
8 INT55957 Positive_regulation of PRNP 57 0.67 37.87 7.11 91.52
9 INT124643 Binding of DYNLL1 3 0.36 0.9 0.23 90.96
10 INT149704 Positive_regulation of Gene_expression of Insl3 1 0.30 0.57 0.24 90.56
11 INT62763 Binding of GFER 3 0.48 0.66 0.06 90.48
12 INT5780 Regulation of Gene_expression of Calca 90 0.62 59.52 85.03 90.40
13 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65 89.52
14 INT1912 Gene_expression of Calca 1152 0.78 453.25 739.84 88.96
15 INT64700 Binding of Nf1 14 0.45 15.24 2.29 88.08
16 INT84510 Positive_regulation of Nf1 8 0.69 9.52 1.93 87.80
17 INT36777 Gene_expression of CTD 12 0.41 11.47 1.42 86.08
18 INT16464 Phosphorylation of FTH1 1 0.80 0.61 0.53 85.64
19 INT51757 Gene_expression of COBRA1 4 0.51 2.71 0.75 83.12
20 INT101992 Localization of VEGFA 413 0.81 258.23 36.15 81.68
21 INT157666 Positive_regulation of GOPC 335 0.60 120.19 42.75 80.68
22 INT16290 Gene_expression of BSG 60 0.68 38.73 32.86 80.36
23 INT157589 Binding of Tdrd6 1 0.40 1.12 0.15 79.40
24 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 79.04
25 INT16463 Gene_expression of FTH1 15 0.65 6.28 2.66 76.80
26 INT27146 Negative_regulation of Regulation of Calca 4 0.43 1.18 2.9 76.48
27 INT2649 Regulation of Calca 433 0.62 146.05 330.95 76.16
28 INT170855 Negative_regulation of GOPC 188 0.38 70.92 15.41 71.44
29 INT4760 Negative_regulation of Gene_expression of Calca 93 0.59 34.19 60.3 71.12
30 INT131645 Negative_regulation of Nf1 10 0.58 8.12 1.24 70.84
31 INT86999 Regulation of DYNLL1 5 0.44 2.85 2.18 70.24
32 INT22785 Negative_regulation of PRNP 12 0.57 5.09 1.57 70.08
33 INT227921 Regulation of Binding of MMRN1 1 0.02 1.65 0.94 70.04
34 INT91432 Binding of MMRN1 23 0.36 9.79 2.95 70.04
35 INT175655 Regulation of MMRN1 16 0.12 9.96 2.12 70.04
36 INT77601 Gene_expression of OR51B4 15 0.58 2.07 6.19 66.52
37 INT30531 Gene_expression of C2 15 0.66 5.5 1.99 66.32
38 INT68179 Gene_expression of Nf1 9 0.78 8.87 0.68 66.32
39 INT245736 Gene_expression of DISC1 13 0.61 7.65 1.33 65.00
40 INT159466 Gene_expression of Snrpf 7 0.60 1.32 0.97 55.44
41 INT94453 Gene_expression of ITGB1 50 0.75 18.41 4.72 53.84
42 INT227925 Negative_regulation of Gene_expression of ITGB1 1 0.02 2.19 1.12 53.84
43 INT21687 Positive_regulation of ras 143 0.58 97.34 27.31 50.68
44 INT101441 Positive_regulation of FTH1 15 0.54 7.03 3.22 50.00
45 INT6511 Positive_regulation of AFP 76 0.70 70.15 7.28 48.32
46 INT161549 Negative_regulation of TDRD6 2 0.17 1.08 0.58 46.24
47 INT333440 Protein_catabolism of Lif 1 0.23 0.2 0.08 36.48
48 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 35.96
49 INT97768 Positive_regulation of Gene_expression of PLG 5 0.49 2.49 0.89 30.84
50 INT4561 Gene_expression of PLG 32 0.75 17.59 6.21 30.28
51 INT169172 Positive_regulation of XIAP 3 0.49 2.54 0.12 29.00
52 INT41893 Negative_regulation of HBS1L 16 0.23 8.98 1.19 26.84
53 INT79261 Positive_regulation of Gene_expression of COL1A1 24 0.36 7.49 2.45 25.16
54 INT74293 Positive_regulation of BAK1 13 0.60 14.13 2.73 25.00
55 INT19963 Gene_expression of COL1A1 118 0.59 42.11 15.15 24.60
56 INT20552 Negative_regulation of Gene_expression of COL2A1 29 0.56 11.92 4.81 20.48
57 INT11659 Gene_expression of COL2A1 164 0.78 78.49 22.58 19.88
58 INT190026 Positive_regulation of Gene_expression of Nf1 3 0.53 2.45 0.07 18.08
59 INT248660 Localization of CERS2 1 0.47 0.26 0 16.08
60 INT9660 Regulation of TNF 363 0.62 312.94 139.99 14.08
61 INT647 Gene_expression of SGCG 211 0.75 78.46 55.82 12.56
62 INT15610 Localization of GOPC 223 0.65 68.26 28.7 9.32
63 INT77619 Gene_expression of Prkaca 43 0.75 8.55 14.13 8.88
64 INT74166 Positive_regulation of C2 10 0.55 2.83 1.05 8.72
65 INT61993 Gene_expression of NF1 29 0.78 34.47 1.23 8.52
66 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 5.00
67 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98 5.00
68 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 5.00
69 INT34869 Negative_regulation of PTGS2 778 0.59 366.76 319.85 5.00
70 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97 5.00
71 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 5.00
72 INT15515 Positive_regulation of Crp 700 0.70 604.24 150.15 5.00
73 INT425 Localization of PRL 455 0.81 189.64 144.8 5.00
74 INT252 Localization of GH1 529 0.80 227.4 122.05 5.00
75 INT9235 Negative_regulation of Gene_expression of TNF 346 0.59 252.98 118.61 5.00
76 INT11051 Positive_regulation of Gene_expression of IL6 415 0.69 319.21 109.3 5.00
77 INT60526 Gene_expression of IL10 449 0.78 292.71 107.84 5.00
78 INT12082 Localization of IL6 365 0.81 241.78 105.78 5.00
79 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 5.00
80 INT914 Positive_regulation of GH1 292 0.69 100.7 84.91 5.00
81 INT9236 Regulation of Gene_expression of TNF 204 0.62 162.66 72.99 5.00
82 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73 5.00
83 INT1603 Negative_regulation of Rtcd1 131 0.51 29.99 66.66 5.00
84 INT17401 Gene_expression of IGF1 475 0.78 232.18 62.07 5.00
85 INT1759 Gene_expression of TIMP1 267 0.77 133.87 59.29 5.00
86 INT9234 Negative_regulation of Gene_expression of IL6 171 0.59 101.61 53.15 5.00
87 INT52264 Gene_expression of IK 180 0.77 90.87 51.87 5.00
88 INT83199 Gene_expression of Nos3 193 0.78 100.72 51.57 5.00
89 INT531 Gene_expression of GH1 376 0.75 193.45 46.24 5.00
90 INT2774 Binding of Crp 241 0.48 195.89 44.39 5.00
91 INT73502 Positive_regulation of IL10 154 0.69 124.87 43.5 5.00
92 INT613 Gene_expression of Alb 268 0.78 149.84 42.78 5.00
93 INT2389 Regulation of PTGS1 86 0.61 31.23 28.95 5.00
94 INT129956 Gene_expression of MMP13 145 0.72 60.48 26.98 5.00
95 INT9682 Positive_regulation of IGF1 238 0.70 120.03 26.36 5.00
96 INT50490 Regulation of PTGS2 80 0.48 39.51 25.85 5.00
97 INT70048 Positive_regulation of Gene_expression of IL10 90 0.55 71.34 25.66 5.00
98 INT14731 Positive_regulation of TGFB1 78 0.67 52.57 22.23 5.00
99 INT11625 Localization of App 98 0.78 55.46 20.86 5.00
100 INT955 Gene_expression of GHRH 126 0.78 59.91 20.74 5.00
101 INT170444 Binding of Gopc 172 0.39 45.05 20.71 5.00
102 INT105021 Binding of GOPC 187 0.40 60.39 20.38 5.00
103 INT16794 Binding of App 103 0.48 64.87 19.79 5.00
104 INT65502 Regulation of App 77 0.62 52.05 19.44 5.00
105 INT756 Gene_expression of C3 138 0.75 100.6 19.2 5.00
106 INT14724 Negative_regulation of CYP19A1 233 0.59 96.56 18.26 5.00
107 INT12081 Localization of TGFB1 64 0.81 35.4 17.47 5.00
108 INT3364 Binding of SGCG 87 0.47 31.93 17.24 5.00
109 INT5333 Gene_expression of NPEPPS 45 0.65 26.34 15.25 5.00
110 INT27739 Positive_regulation of EGF 49 0.70 28.31 13.68 5.00
111 INT174844 Binding of Fig4 81 0.41 18.03 12.87 5.00
112 INT123779 Positive_regulation of MMP13 42 0.65 24.3 12.45 5.00
113 INT70050 Negative_regulation of IL10 56 0.58 37.45 12.39 5.00
114 INT75955 Gene_expression of Drd3 19 0.77 4.39 10.07 5.00
115 INT81929 Negative_regulation of Gene_expression of IL10 41 0.57 27.99 9.87 5.00
116 INT2036 Localization of EGF 42 0.77 21.5 9.74 5.00
117 INT38564 Binding of AIS 36 0.38 27.77 9.31 5.00
118 INT73497 Regulation of IL10 33 0.45 22.6 9.19 5.00
119 INT33220 Negative_regulation of ras 110 0.58 70.21 9.19 5.00
120 INT35269 Localization of SGCG 38 0.78 14.68 9.01 5.00
121 INT73558 Regulation of IK 23 0.23 12.02 8.73 5.00
122 INT129962 Positive_regulation of Gene_expression of MMP13 41 0.65 20.74 8.54 5.00
123 INT17024 Gene_expression of COL1A2 69 0.77 36.38 8.29 5.00
124 INT147583 Gene_expression of AIS 82 0.58 48.7 7.11 5.00
125 INT95117 Gene_expression of PDGFA 71 0.71 51.17 6.9 5.00
126 INT28861 Binding of Gh 61 0.46 25.61 6.38 5.00
127 INT9683 Binding of GH1 57 0.47 21.14 5.99 5.00
128 INT174851 Positive_regulation of COL5A2 46 0.54 12.73 5.48 5.00
129 INT126751 Regulation of Gene_expression of IL10 16 0.44 10.84 5.22 5.00
130 INT105393 Positive_regulation of Localization of VEGFA 66 0.70 45.45 4.9 5.00
131 INT142162 Binding of IL10 30 0.37 21.9 4.84 5.00
132 INT100772 Negative_regulation of TXNRD1 10 0.41 3.47 4.74 5.00
133 INT140350 Binding of C2 17 0.36 3.97 4.69 5.00
134 INT47451 Positive_regulation of Positive_regulation of ras 18 0.35 10.07 4.6 5.00
135 INT22080 Regulation of ras 40 0.53 36.24 4.44 5.00
136 INT217742 Positive_regulation of Gene_expression of COL2A1 20 0.67 9.76 4.23 5.00
137 INT76714 Binding of Drd3 9 0.37 2.33 4.09 5.00
138 INT33951 Regulation of TXNRD1 18 0.51 6.97 4.02 5.00
139 INT45147 Gene_expression of C2 21 0.58 6.18 3.98 5.00
140 INT9677 Negative_regulation of Gene_expression of GH1 46 0.48 23.32 3.68 5.00
141 INT149614 Localization of MMP13 13 0.81 6.12 3.65 5.00
142 INT129960 Negative_regulation of Gene_expression of MMP13 19 0.53 7.17 3.55 5.00
143 INT173878 Gene_expression of ACAN 32 0.75 9.35 3.55 5.00
144 INT82265 Gene_expression of Lif 7 0.50 6.17 3.4 5.00
145 INT62061 Gene_expression of TRGC1 32 0.69 17.43 3.37 5.00
146 INT98068 Gene_expression of SCN2A 19 0.75 14.42 3.31 5.00
147 INT22375 Localization of PDGFA 21 0.75 15.46 3.25 5.00
148 INT155039 Gene_expression of ADAMTS5 23 0.67 7.85 3.22 5.00
149 INT76240 Positive_regulation of Lif 6 0.69 6.04 3.13 5.00
150 INT66367 Gene_expression of Gsk3b 16 0.45 9.75 3.07 5.00
151 INT24821 Binding of VTN 14 0.47 5.83 3 5.00
152 INT239083 Binding of PPY 9 0.32 7.59 2.9 5.00
153 INT47011 Positive_regulation of Gusb 14 0.44 8.93 2.87 5.00
154 INT14448 Localization of COL5A2 34 0.67 17.35 2.85 5.00
155 INT99419 Regulation of Drd3 7 0.48 1.89 2.81 5.00
156 INT78248 Negative_regulation of Cdkn2a 17 0.59 15.15 2.8 5.00
157 INT103020 Gene_expression of SGCA 22 0.56 14.29 2.75 5.00
158 INT89327 Positive_regulation of Gene_expression of Drd3 4 0.54 0.32 2.64 5.00
159 INT68091 Localization of COL1A1 19 0.66 9.13 2.56 5.00
160 INT15540 Positive_regulation of PDGFA 24 0.47 19.01 2.5 5.00
161 INT173592 Binding of COL5A2 32 0.33 9.14 2.48 5.00
162 INT204019 Negative_regulation of C2 10 0.26 6.23 2.44 5.00
163 INT183668 Binding of SGCA 15 0.36 9.86 2.42 5.00
164 INT102639 Positive_regulation of VDR 31 0.69 18.05 2.38 5.00
165 INT2544 Localization of PTH 39 0.81 30.55 2.22 5.00
166 INT22738 Negative_regulation of DYNLL1 17 0.57 6.68 2.06 5.00
167 INT113717 Negative_regulation of Gene_expression of COL1A1 21 0.41 6.14 2.01 5.00
168 INT64709 Gene_expression of VTN 11 0.67 11.01 1.97 5.00
169 INT58208 Negative_regulation of Ctsl 8 0.53 3.49 1.91 5.00
170 INT68181 Binding of Nf1 6 0.48 8.14 1.88 5.00
171 INT5331 Positive_regulation of Gene_expression of NPEPPS 6 0.49 3.74 1.81 5.00
172 INT17452 Regulation of Dlst 14 0.46 1.5 1.68 5.00
173 INT114628 Positive_regulation of Gene_expression of SGCA 4 0.42 2.2 1.62 5.00
174 INT149762 Regulation of MAS1 8 0.31 5.34 1.61 5.00
175 INT94827 Gene_expression of HBS1L 24 0.67 26.11 1.61 5.00
176 INT203116 Positive_regulation of ACAN 6 0.67 3.98 1.56 5.00
177 INT81982 Gene_expression of Bmpr2 36 0.60 14.58 1.55 5.00
178 INT12085 Positive_regulation of Localization of TGFB1 7 0.42 4.9 1.4 5.00
179 INT67133 Gene_expression of Gusb 14 0.75 18.57 1.37 5.00
180 INT117232 Localization of COL2A1 11 0.72 7.34 1.3 5.00
181 INT134036 Regulation of Gsk3b 4 0.60 1.42 1.15 5.00
182 INT134661 Negative_regulation of Tp53 11 0.43 10.91 1.13 5.00
183 INT67188 Gene_expression of OPLL 10 0.52 4.58 1.12 5.00
184 INT32545 Localization of Gsk3b 9 0.07 2.88 1.11 5.00
185 INT101104 Positive_regulation of Gene_expression of COL1A2 12 0.69 5.87 1.09 5.00
186 INT181973 Positive_regulation of MAS1 8 0.49 7.64 1.07 5.00
187 INT55688 Gene_expression of MMP11 15 0.74 10.95 1.06 5.00
188 INT133102 Negative_regulation of Gene_expression of COL1A2 8 0.08 2.56 1.02 5.00
189 INT131488 Binding of MAS1 9 0.36 8.49 1.01 5.00
190 INT1940 Localization of PIK3C2A 8 0.78 7.28 1.01 5.00
191 INT189130 Regulation of AIS 11 0.39 7.64 0.99 5.00
192 INT256742 Positive_regulation of Cdr1 10 0.27 2.89 0.81 5.00
193 INT139845 Negative_regulation of Cyp4f18 4 0.28 0.95 0.78 5.00
194 INT261468 Binding of Snrpf 4 0.17 1.66 0.71 5.00
195 INT116249 Positive_regulation of LARS 6 0.39 4.16 0.71 5.00
196 INT252166 Negative_regulation of Cdr1 6 0.17 2.42 0.69 5.00
197 INT148341 Gene_expression of MAS1 9 0.65 4.19 0.68 5.00
198 INT179133 Localization of Nf1 2 0.80 2.18 0.68 5.00
199 INT211972 Regulation of Best1 18 0.33 12.04 0.67 5.00
200 INT203118 Positive_regulation of Gene_expression of ACAN 5 0.49 1.7 0.61 5.00
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