D:Pseudotumor Cerebri

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pChart

Disease Term
Synonyms BENIGN INTRACRANIAL HYPERTENSION, Hypertension Benign Intracranial, Hypertension Idiopathic Intracranial, Idiopathic Intracranial Hypertension, Intracranial Hypertension Benign, Intracranial Hypertension Idiopathic
Documents 329
Hot Single Events 38
Hot Interactions 3

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Pseudotumor Cerebri. They are ordered first by their relevance to Pseudotumor Cerebri and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT245503 SST Regulation of Gene_expression of CSF2 1 0.06 0.67 0.39 90.00
2 INT142075 IL4 Negative_regulation of Binding of IDO1 1 0.02 2.07 1.19 83.52
3 INT142077 TGFB1 Negative_regulation of Binding of IDO1 1 0.15 2.07 1.19 83.52
4 INT142076 IL4 Negative_regulation of Gene_expression of IFNG 1 0.01 1.58 0.64 25.00
5 INT246468 GHS Regulation of Gh 1 0.05 1.12 0.19 5.00
6 INT259023 CADPS Positive_regulation of Binding of SH2B2 1 0.06 2.05 0.14 5.00
7 INT257937 Binding of CSF2 and INVS 1 0.04 1.1 0.14 5.00
8 INT246466 GHS Positive_regulation of GHS Regulation of Gh 1 0.01 0.6 0.1 5.00
9 INT173948 Gh Positive_regulation of Gene_expression of IGF1 2 0.36 0.77 0.1 5.00
10 INT246467 GHS Regulation of Localization of Gh 1 0.03 0.52 0.09 5.00
11 INT352579 CNTF Negative_regulation of Gene_expression of NPY 1 0.17 0.89 0.07 5.00
12 INT246469 Binding of IGF1 and Gh 1 0.03 0.2 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Pseudotumor Cerebri. They are ordered first by their pain relevance and then by number of times they were reported in Pseudotumor Cerebri. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT35584 Binding of ACLY 22 0.35 31.78 7.17 100.00
2 INT163969 Positive_regulation of Hypt 6 0.41 6.24 0.49 100.00
3 INT1497 Negative_regulation of Gh 415 0.59 192.95 74.71 99.64
4 INT2451 Positive_regulation of Avp 355 0.70 102.66 147.69 99.46
5 INT27345 Positive_regulation of ANIB1 9 0.07 9.81 3.46 99.34
6 INT5298 Negative_regulation of MTHFS 70 0.57 27.07 28.11 98.92
7 INT49750 Negative_regulation of CPOX 735 0.58 360.06 274.19 98.24
8 INT48390 Negative_regulation of Localization of CSF2 10 0.51 7.39 3.28 98.20
9 INT142082 Positive_regulation of IDO1 17 0.60 9.46 6.33 98.12
10 INT48593 Positive_regulation of NOS1 420 0.68 226.15 114.71 97.96
11 INT28861 Binding of Gh 61 0.46 25.61 6.38 97.84
12 INT11554 Negative_regulation of CSF2 129 0.59 108.55 29.44 97.76
13 INT307615 Negative_regulation of Positive_regulation of CSF2 4 0.36 3.55 0.48 97.76
14 INT4960 Positive_regulation of CSF2 285 0.70 256.73 65.73 97.76
15 INT14690 Localization of CSF2 124 0.80 85.17 27.26 97.64
16 INT19768 Negative_regulation of LAMC2 11 0.57 10.54 5.32 96.56
17 INT75908 Regulation of LEP 77 0.60 60.16 15.19 96.46
18 INT1498 Gene_expression of Gh 521 0.75 220.84 81.16 96.12
19 INT21032 Gene_expression of Adh1 23 0.78 22.1 6.14 94.76
20 INT4358 Positive_regulation of Localization of Avp 195 0.70 30.79 77.58 93.68
21 INT7470 Positive_regulation of Gene_expression of Avp 37 0.70 19.55 19.96 93.68
22 INT11587 Gene_expression of CSF2 645 0.78 544.38 93.89 93.36
23 INT1273 Gene_expression of Avp 356 0.78 90.56 138.7 93.00
24 INT477 Localization of Avp 813 0.81 131.58 300.4 92.60
25 INT921 Regulation of GH1 172 0.60 52.88 51.04 92.08
26 INT639 Regulation of LAMC2 8 0.44 4.68 2.92 91.16
27 INT5118 Regulation of SST 97 0.62 34.35 51.74 90.00
28 INT59454 Regulation of Gene_expression of CSF2 22 0.52 19.67 2.69 89.36
29 INT9082 Positive_regulation of ESR1 238 0.69 148.51 36.69 87.84
30 INT72923 Positive_regulation of MCRS1 72 0.50 99.19 30.36 87.20
31 INT17271 Positive_regulation of CDNF 11 0.28 2.69 5.03 85.96
32 INT4159 Gene_expression of Hp 33 0.72 12.49 8.39 85.88
33 INT142081 Binding of IDO1 4 0.21 2.55 1.73 83.52
34 INT257938 Binding of HYDIN 1 0.01 3.74 0.39 82.64
35 INT3777 Positive_regulation of NARFL 256 0.56 302.43 25.74 82.20
36 INT162 Regulation of Prl 794 0.62 165.01 322.24 82.16
37 INT102658 Negative_regulation of Gene_expression of CSF2 42 0.50 38.63 8.32 81.16
38 INT822 Gene_expression of ESR1 529 0.78 302.16 63.64 80.68
39 INT60526 Gene_expression of IL10 449 0.78 292.71 107.84 76.72
40 INT56298 Gene_expression of IL4 306 0.78 182.18 72.92 76.72
41 INT14740 Gene_expression of TGFB1 272 0.78 168.48 60.18 76.72
42 INT228298 Gene_expression of INVS 10 0.65 6.44 0.43 75.96
43 INT1258 Positive_regulation of Tshr 3 0.54 1.12 0.74 75.00
44 INT259037 Negative_regulation of Binding of ACLY 1 0.07 1.54 0.13 72.80
45 INT257939 Transcription of CEBPZ 1 0.10 0.93 0.34 68.28
46 INT18010 Positive_regulation of CD40LG 122 0.70 100.8 18.46 64.72
47 INT77670 Positive_regulation of ACLY 24 0.49 21.68 3.12 64.56
48 INT10214 Gene_expression of VIM 153 0.78 115.88 16.29 62.08
49 INT25963 Gene_expression of DES 122 0.75 98.81 11.25 62.08
50 INT184895 Gene_expression of MCRS1 46 0.42 56.03 19.44 61.16
51 INT78024 Gene_expression of ACLY 73 0.75 59.15 18.54 60.00
52 INT4988 Gene_expression of KRT1 64 0.77 43.4 4.12 59.92
53 INT8773 Gene_expression of HBG1 58 0.76 37.6 4.59 59.44
54 INT142083 Positive_regulation of AIF1 4 0.12 4.86 0.77 59.12
55 INT142079 Negative_regulation of Positive_regulation of AIF1 1 0.00 1.01 0.57 59.12
56 INT352588 Regulation of CAMKK2 1 0.17 1.24 0.15 58.48
57 INT352589 Regulation of Regulation of CAMKK2 1 0.17 1.24 0.15 58.48
58 INT11685 Regulation of CSF2 99 0.59 58.82 15.9 57.92
59 INT3793 Regulation of CEBPZ 59 0.61 20.91 15.83 57.24
60 INT111607 Gene_expression of CDH1 103 0.75 90.45 7.77 55.68
61 INT128030 Gene_expression of GJA1 23 0.75 7.81 1.88 55.68
62 INT80498 Gene_expression of DSP 15 0.75 7.06 0.79 55.68
63 INT8188 Positive_regulation of Adrb3 27 0.68 7.32 10.44 54.64
64 INT62124 Gene_expression of NOS1 444 0.78 218.08 114.85 54.16
65 INT90909 Negative_regulation of Gene_expression of NOS1 44 0.55 23.83 12.47 54.16
66 INT48908 Transcription of NOS1 27 0.55 13.46 8.39 54.16
67 INT48767 Negative_regulation of NOS1 312 0.59 154.25 90.32 51.60
68 INT1893 Localization of Gh 1041 0.79 340.23 256.58 49.80
69 INT63349 Gene_expression of PECAM1 199 0.75 166.03 36.76 48.24
70 INT188173 Gene_expression of CDH5 14 0.49 3.17 0.44 48.24
71 INT5865 Positive_regulation of Localization of Gh 282 0.69 84.86 93.5 47.16
72 INT14714 Negative_regulation of NPY 10 0.58 4.41 4.52 46.80
73 INT5095 Localization of Ghrh 185 0.81 28.09 62.08 46.56
74 INT9179 Positive_regulation of Localization of Ghrh 42 0.70 7.05 18.1 46.56
75 INT181868 Localization of ACLY 5 0.62 6.36 1.4 46.44
76 INT4216 Gene_expression of CD40LG 328 0.78 256.02 44.23 42.92
77 INT9100 Negative_regulation of CAMKK2 3 0.48 4.89 0.93 41.52
78 INT142078 Negative_regulation of IDO1 3 0.14 2.59 1.23 40.64
79 INT259030 Negative_regulation of Gene_expression of ACLY 1 0.07 1.95 0.08 34.80
80 INT58192 Positive_regulation of MRI1 86 0.61 53.81 24.68 32.04
81 INT13454 Positive_regulation of Positive_regulation of Gh 49 0.68 14.53 18.49 25.20
82 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 25.00
83 INT5056 Gene_expression of IFNG 216 0.78 137.52 74.57 25.00
84 INT73502 Positive_regulation of IL10 154 0.69 124.87 43.5 25.00
85 INT62042 Positive_regulation of Gene_expression of IL4 67 0.56 42.05 20.39 25.00
86 INT56301 Positive_regulation of IL4 68 0.56 54.51 18.65 25.00
87 INT25223 Positive_regulation of Gene_expression of IFNG 41 0.67 36.97 15.89 25.00
88 INT110 Regulation of Adrb3 33 0.60 8.09 13.84 25.00
89 INT5057 Negative_regulation of Gene_expression of IFNG 23 0.58 8.33 12.3 25.00
90 INT61628 Negative_regulation of Gene_expression of IL4 31 0.55 20.96 8.18 25.00
91 INT77146 Binding of IL4 23 0.36 13.69 5.39 25.00
92 INT142080 Protein_catabolism of IDO1 2 0.27 1.47 0.55 25.00
93 INT15458 Gene_expression of NPY 50 0.76 22.67 23.03 24.00
94 INT17544 Negative_regulation of Gene_expression of NPY 3 0.42 1.97 1.05 24.00
95 INT3448 Positive_regulation of Gh 521 0.69 180.03 161.18 23.40
96 INT17401 Gene_expression of IGF1 475 0.78 232.18 62.07 19.60
97 INT246465 Regulation of GHS 3 0.15 2.85 0.28 17.52
98 INT9178 Regulation of Localization of Ghrh 13 0.45 2.28 5.08 15.40
99 INT128868 Positive_regulation of Mcrs1 3 0.03 3.26 2.31 13.28
100 INT7364 Regulation of Ghrh 49 0.58 8.05 19.05 7.80
101 INT812 Localization of INS 1026 0.81 515.6 145.31 5.00
102 INT1530 Regulation of Gh 382 0.61 115.96 112.47 5.00
103 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 5.00
104 INT397 Localization of SST 232 0.81 58.05 101.19 5.00
105 INT8347 Gene_expression of SST 181 0.78 104.59 65.45 5.00
106 INT3161 Regulation of Localization of Gh 163 0.61 35.43 59.45 5.00
107 INT21737 Binding of MC1R 129 0.48 45.45 56.54 5.00
108 INT251 Regulation of INS 398 0.62 232.47 55.04 5.00
109 INT2463 Localization of CCK 101 0.81 37.54 47.59 5.00
110 INT1894 Negative_regulation of Localization of Gh 168 0.58 64.12 43.56 5.00
111 INT16194 Binding of CNR1 82 0.48 20.75 39.59 5.00
112 INT3252 Negative_regulation of INS 428 0.59 271.65 39.52 5.00
113 INT3253 Negative_regulation of Localization of INS 205 0.59 130.39 36.61 5.00
114 INT2274 Regulation of Localization of INS 101 0.62 41.55 34.79 5.00
115 INT692 Negative_regulation of SST 72 0.59 28.68 34.52 5.00
116 INT5100 Positive_regulation of Ghrh 100 0.64 24.2 30.21 5.00
117 INT9682 Positive_regulation of IGF1 238 0.70 120.03 26.36 5.00
118 INT17625 Localization of GCG 210 0.80 55.69 24.97 5.00
119 INT693 Negative_regulation of Localization of SST 46 0.59 8.57 21.75 5.00
120 INT16396 Negative_regulation of CEBPZ 76 0.48 30.03 21.6 5.00
121 INT14737 Gene_expression of FN1 117 0.78 78.74 18.99 5.00
122 INT7414 Regulation of Localization of SST 31 0.60 4.85 17.46 5.00
123 INT10841 Positive_regulation of Gene_expression of Gh 101 0.59 45.39 16.96 5.00
124 INT2243 Localization of GAST 67 0.81 34.54 16.19 5.00
125 INT62681 Negative_regulation of LEP 93 0.59 66.97 15.77 5.00
126 INT180497 Binding of MRI1 45 0.42 28.35 14.77 5.00
127 INT7366 Negative_regulation of Ghrh 42 0.58 7.72 14.45 5.00
128 INT22301 Positive_regulation of Gene_expression of CSF2 66 0.63 59.49 14.24 5.00
129 INT184890 Regulation of MCRS1 35 0.22 44.35 13.78 5.00
130 INT16530 Gene_expression of Ghrh 45 0.77 6.22 13.44 5.00
131 INT28952 Negative_regulation of Gene_expression of IGF1 75 0.58 41.11 12.32 5.00
132 INT10847 Gene_expression of LAMC2 39 0.75 27 12.09 5.00
133 INT19010 Negative_regulation of Localization of Ghrh 27 0.57 4.85 10.5 5.00
134 INT72924 Negative_regulation of MCRS1 27 0.19 33.59 10.29 5.00
135 INT11729 Regulation of IGF1 71 0.61 44.58 9.71 5.00
136 INT11510 Negative_regulation of Positive_regulation of Gh 28 0.52 12.71 9.16 5.00
137 INT14301 Binding of CSF2 82 0.48 67.95 8.98 5.00
138 INT34777 Localization of IGF1 82 0.80 42.68 8.62 5.00
139 INT175554 Binding of MCRS1 21 0.23 25.2 8.59 5.00
140 INT1499 Negative_regulation of Gene_expression of Gh 58 0.42 25.17 7.86 5.00
141 INT17501 Negative_regulation of F2 70 0.58 32.23 7.51 5.00
142 INT47994 Negative_regulation of Lipg 45 0.50 27.19 7.24 5.00
143 INT8683 Positive_regulation of F3 31 0.67 42.89 6.21 5.00
144 INT63351 Negative_regulation of Gene_expression of PECAM1 19 0.52 16.06 5.73 5.00
145 INT64888 Negative_regulation of HBM 52 0.16 34.33 5.45 5.00
146 INT18661 Localization of Ghsr 32 0.78 3.19 5.2 5.00
147 INT82354 Positive_regulation of PECAM1 25 0.34 22.93 4.69 5.00
148 INT87632 Positive_regulation of Gene_expression of PECAM1 32 0.45 29.47 4.66 5.00
149 INT19008 Positive_regulation of Positive_regulation of Ghrh 15 0.49 2.4 4.55 5.00
150 INT102187 Gene_expression of SH2B2 23 0.59 26.54 4.39 5.00
151 INT2242 Negative_regulation of Localization of GAST 12 0.58 5.55 4.22 5.00
152 INT19104 Regulation of Gene_expression of Gh 24 0.40 8.42 3.88 5.00
153 INT87517 Gene_expression of LDLR 73 0.69 37.35 3.32 5.00
154 INT175262 Binding of SH2B2 18 0.36 22.85 3.18 5.00
155 INT131187 Regulation of Gene_expression of IGF1 18 0.62 11.18 3.05 5.00
156 INT61791 Positive_regulation of SH2B2 9 0.50 8.36 2.99 5.00
157 INT16130 Binding of IGF1 67 0.48 27.43 2.95 5.00
158 INT53906 Positive_regulation of Negative_regulation of Gh 9 0.50 6.72 2.73 5.00
159 INT20028 Positive_regulation of Gene_expression of Ghrh 9 0.50 1.52 2.62 5.00
160 INT60765 Gene_expression of LAMB2 28 0.49 13.93 2.38 5.00
161 INT209501 Gene_expression of CADPS 15 0.65 20.7 2.22 5.00
162 INT144356 Gene_expression of GHS 4 0.57 10.76 2.21 5.00
163 INT100620 Localization of VIM 8 0.76 5.47 2.16 5.00
164 INT11183 Negative_regulation of SH2B2 4 0.34 6.99 2.12 5.00
165 INT9908 Negative_regulation of IAPP 29 0.57 19.37 2.12 5.00
166 INT152771 Gene_expression of TJP1 19 0.75 14.95 1.98 5.00
167 INT70538 Regulation of Localization of CSF2 4 0.54 3.08 1.9 5.00
168 INT124322 Negative_regulation of PNLIP 11 0.31 6.53 1.88 5.00
169 INT77415 Localization of GLP1R 23 0.63 11.1 1.69 5.00
170 INT117033 Gene_expression of JAG1 13 0.65 11.46 1.52 5.00
171 INT12035 Regulation of F2 21 0.45 12.66 1.47 5.00
172 INT259036 Transcription of SH2B2 2 0.55 7.01 1.46 5.00
173 INT352585 Negative_regulation of MCHR1 1 0.23 1.71 1.32 5.00
174 INT236277 Positive_regulation of Gene_expression of CADPS 5 0.42 9.17 1.29 5.00
175 INT18478 Protein_catabolism of CSF2 6 0.88 1.75 1.26 5.00
176 INT209503 Positive_regulation of CADPS 3 0.42 7 1.11 5.00
177 INT72129 Positive_regulation of Positive_regulation of IGF1 11 0.50 4.61 1.05 5.00
178 INT164400 Positive_regulation of CNTF 3 0.49 1.66 0.96 5.00
179 INT352587 Transcription of CNTF 1 0.30 5.18 0.84 5.00
180 INT111289 Regulation of MC4R 4 0.43 1 0.78 5.00
181 INT11919 Regulation of KRT1 9 0.10 4.97 0.77 5.00
182 INT246463 Negative_regulation of GHS 2 0.17 2.73 0.75 5.00
183 INT102377 Binding of GHS 4 0.22 2.62 0.7 5.00
184 INT87445 Localization of TJP1 2 0.45 0.55 0.68 5.00
185 INT29460 Regulation of Gene_expression of Ghrh 3 0.31 0.3 0.68 5.00
186 INT148382 Positive_regulation of JAG1 5 0.23 3.88 0.63 5.00
187 INT352586 Positive_regulation of MCHR1 1 0.27 0.74 0.58 5.00
188 INT52740 Binding of ACLS 5 0.31 3 0.54 5.00
189 INT293957 Localization of PION 1 0.55 2 0.53 5.00
190 INT125578 Positive_regulation of Localization of IGF1 6 0.60 7.59 0.53 5.00
191 INT246464 Positive_regulation of Gene_expression of GHS 2 0.27 4.68 0.51 5.00
192 INT136415 Localization of GHS 6 0.70 3.83 0.49 5.00
193 INT70445 Binding of KRT1 10 0.35 5.38 0.47 5.00
194 INT259035 Localization of SH2B2 3 0.43 1.77 0.42 5.00
195 INT51148 Gene_expression of CDH16 6 0.34 2.42 0.42 5.00
196 INT70449 Binding of SLC4A1 5 0.36 5.1 0.38 5.00
197 INT163489 Binding of CDH1 13 0.19 8.63 0.35 5.00
198 INT259031 Negative_regulation of Gene_expression of CADPS 1 0.07 3.04 0.35 5.00
199 INT257940 Gene_expression of HYDIN 1 0.02 1.46 0.31 5.00
200 INT188760 Regulation of ZC3H12A 4 0.04 4.02 0.27 5.00
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