D:Psoriasis

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Disease Term
Synonyms ANTIPSORIATIC, Dermal Erythematous Plaques, ERYTHRODERMIC PSORIASIS, Keratinocyte Hyperproliferation, Palmoplantar Pustulosis, Palmoplantaris Pustulosis, Papulosquamous Disease, Papulosquamous Disorder, PSORIASES, Psoriatic, Pustular Psoriasis
Documents 1327
Hot Single Events 200
Hot Interactions 107

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Psoriasis. They are ordered first by their relevance to Psoriasis and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT329170 DCPS Positive_regulation of Gene_expression of IFN1@ 1 0.04 1.55 0.36 100.00
2 INT325315 Binding of STAT3 and TH1L 1 0.16 0.6 0.23 100.00
3 INT325314 Binding of IL12A and STAT3 1 0.19 0.6 0.22 100.00
4 INT122096 Binding of HLA-B and SFTPA1 2 0.04 1.81 0.6 100.00
5 INT349290 Binding of HLA-B and SPATA19 1 0.00 1.25 0.4 100.00
6 INT349289 Binding of SPATA19 and SFTPA1 1 0.03 1.2 0.4 100.00
7 INT328205 Binding of PSG5 and PSORS4 1 0.01 0.5 0.25 100.00
8 INT328204 Binding of DSG3 and PSORS4 1 0.00 0.5 0.25 100.00
9 INT306732 Il17a Positive_regulation of Gene_expression of Il2 1 0.09 1.07 0.46 99.78
10 INT131163 Negative_regulation of Binding of CD58 and Cd2 1 0.01 0.6 0.09 99.78
11 INT325317 Binding of IL12A and TH1L 1 0.18 0.59 0.22 99.60
12 INT306731 Il22 Positive_regulation of Gene_expression of Il2 1 0.12 1.07 0.46 99.58
13 INT131162 Binding of CD58 and Cd2 1 0.01 1.21 0.18 99.56
14 INT162396 Binding of LCE3B and LCE3C 1 0.32 1.08 0.45 99.36
15 INT152035 Binding of HLA-A and MRAP 2 0.31 6.95 3.4 99.32
16 INT232653 Binding of CD2 and MLL 1 0.02 0.27 0.1 99.16
17 INT172047 Binding of HLA-A and LRRC23 1 0.22 3.32 1.64 99.00
18 INT306745 Binding of Il12a and IL23A 1 0.10 3.25 1.56 98.96
19 INT172048 Binding of TNF and MICA 1 0.29 1.63 0.62 98.92
20 INT283980 Binding of IL12A and IL23A 2 0.24 1.33 0.57 98.88
21 INT263007 Binding of HLA-DRB6 and IL23R 1 0.01 1.09 0.21 98.66
22 INT325312 IL20 Positive_regulation of Phosphorylation of STAT3 1 0.13 0.58 0.24 98.44
23 INT325316 IL22 Positive_regulation of Phosphorylation of STAT3 1 0.19 0.58 0.24 98.44
24 INT110960 Binding of CD2 and GYPA 1 0.01 0.19 0.05 98.28
25 INT189197 RASGRP1 Positive_regulation of JUN 1 0.07 1.26 0.43 98.04
26 INT189196 RASGRP1 Positive_regulation of SP1 1 0.05 0.63 0.21 98.04
27 INT277828 Negative_regulation of Binding of ICAM1 and ITGAL 2 0.22 1.27 0.57 97.24
28 INT289625 Binding of RS1 and PSORS1C1 1 0.02 1.15 0.17 97.20
29 INT175329 Binding of ICAM1 and ITGAL 14 0.18 10.06 2.81 96.92
30 INT275549 Il10 Positive_regulation of Localization of Hand2 1 0.01 1.3 0.46 96.90
31 INT189199 JUN Positive_regulation of KRT16 1 0.31 0.58 0.22 96.80
32 INT289630 Binding of CDSN and RS1 1 0.02 1.1 0.17 96.68
33 INT275550 Hand1 Positive_regulation of Localization of Hand2 1 0.00 1.29 0.46 96.62
34 INT329173 Binding of PDC and RARRES2 1 0.07 1.02 0.3 96.52
35 INT149117 Binding of CD80 and CTLA4 31 0.52 12.7 7.73 96.12
36 INT155484 Binding of CD86 and CTLA4 15 0.52 8.85 6.09 96.12
37 INT186126 Binding of CD28 and CTLA4 9 0.52 4.13 3.12 96.12
38 INT221847 Binding of Calca and Ntrk1 1 0.03 0.9 0.65 96.12
39 INT186128 Binding of CD2 and CD58 8 0.10 7.59 2.76 95.92
40 INT307765 Myoz1 Positive_regulation of Gene_expression of Il6 1 0.01 0.71 0.21 95.88
41 INT307764 Myoz1 Positive_regulation of Transcription of Il6 1 0.01 0.72 0.21 95.88
42 INT289958 Binding of IL2 and IL2RB 1 0.02 0.59 0.12 95.88
43 INT177977 RUNX1 Regulation of CSF1R 1 0.14 1 0.27 95.84
44 INT155371 VIP Positive_regulation of Localization of IL6 1 0.64 3.37 1.44 95.56
45 INT279400 GANAB Regulation of ITGAL 1 0.01 0.75 0.09 95.28
46 INT232652 Binding of CD2 and ITGAL 1 0.03 0.28 0.09 95.24
47 INT348174 Binding of STAT3 and IL23R 1 0.40 1.9 0.76 95.04
48 INT325028 TNF Negative_regulation of Ptgs1 1 0.00 1.79 0.23 94.88
49 INT271511 Binding of Phb2 and Glrb 1 0.04 1.7 0.84 94.88
50 INT148556 PPARG Regulation of Gene_expression of PPARA 1 0.30 1.2 0.31 94.76
51 INT265213 Binding of Ctla4 and Cd86 2 0.13 1.93 1.31 94.32
52 INT239037 Binding of Cd28 and Cd86 9 0.16 3.69 2.14 94.32
53 INT291377 Binding of CX3CR1 and Cx3cl1 2 0.36 3.57 1.02 94.16
54 INT265210 Binding of Ctla4 and Cd28 2 0.16 1.45 0.93 93.68
55 INT186123 Binding of GIF and IL10 1 0.23 1.17 0.69 93.60
56 INT279361 Binding of TNF and KLF1 4 0.00 3.72 2.19 93.52
57 INT325008 TNF Negative_regulation of Gene_expression of NOSTRIN 1 0.00 1.78 0.23 93.20
58 INT325007 TNF Negative_regulation of NOSTRIN 1 0.00 1.78 0.23 93.20
59 INT194647 Binding of CD28 and CD80 15 0.40 4.9 3.22 92.88
60 INT289959 Negative_regulation of Binding of CD28 and CD80 1 0.07 0.24 0.23 92.88
61 INT186125 Negative_regulation of Binding of CD2 and CD58 3 0.12 3.04 1.06 92.24
62 INT86637 POMC Regulation of Gene_expression of KRT16 2 0.47 1.22 1.61 91.32
63 INT299785 CTLA4 Negative_regulation of Binding of CD28 2 0.17 1.8 0.5 91.12
64 INT299791 Negative_regulation of Binding of CD28 and CTLA4 1 0.18 0.77 0.32 91.12
65 INT194646 Binding of CD28 and CD86 7 0.40 2.69 2.21 90.60
66 INT86179 TNF Positive_regulation of Localization of IL6 5 0.35 1.66 2.17 90.48
67 INT86636 POMC Positive_regulation of Gene_expression of KRT16 2 0.39 0.83 1.28 89.92
68 INT329801 Binding of CAMP and IFNA1 1 0.03 1.48 0.4 89.68
69 INT86638 POMC Negative_regulation of Gene_expression of OPRM1 1 0.34 0.33 0.68 89.56
70 INT299793 Positive_regulation of Binding of CD86 and CTLA4 1 0.17 1.64 0.63 88.56
71 INT299792 Positive_regulation of Binding of CD80 and CTLA4 1 0.17 1.63 0.63 88.56
72 INT289954 Binding of APC and CD28 1 0.03 0.38 0.28 88.56
73 INT325025 Apoa2 Positive_regulation of Hdl1 1 0.05 1.03 0.04 88.52
74 INT266412 Binding of S100A12 and Ager 1 0.01 1.03 0.15 87.88
75 INT184956 ID1 Negative_regulation of CDKN2A 1 0.42 0.21 0 87.84
76 INT225258 Egf Positive_regulation of Gene_expression of S100a7a 1 0.07 1.7 0 87.40
77 INT158400 Binding of CD80 and CD86 3 0.36 0.76 0.48 87.36
78 INT348175 Binding of NIDDM1 and PTPN22 1 0.01 2.36 0.99 86.96
79 INT289955 Binding of APCS and KLF1 1 0.00 0.21 0.23 86.64
80 INT289953 Binding of CD80 and KLF1 1 0.00 0.21 0.23 86.64
81 INT147755 Binding of GNRH1 and TNF 1 0.32 2.37 0.79 86.64
82 INT177982 Binding of RUNX1 and SNRNP70 1 0.01 0.89 0.21 86.32
83 INT48848 Binding of HLA-B and HLA-E 3 0.34 1.95 0.45 85.96
84 INT299788 INCENP Negative_regulation of Gene_expression of NPEPPS 1 0.00 0.86 0.37 85.68
85 INT174459 IL8 Positive_regulation of Gene_expression of Cd74 1 0.00 0.61 0.35 85.60
86 INT186127 CTLA4 Negative_regulation of CD28 1 0.19 0.74 0.32 85.44
87 INT194857 Positive_regulation of Adora2a Positive_regulation of Gene_expression of Vegfa 1 0.23 0.74 0.67 85.44
88 INT299790 IL4 Negative_regulation of Gene_expression of NPEPPS 1 0.00 0.86 0.37 85.28
89 INT325313 IL23A Positive_regulation of Gene_expression of IL22 1 0.20 0.48 0.23 84.96
90 INT155009 IL23A Positive_regulation of Gene_expression of IL17A 2 0.17 0.62 0.39 84.96
91 INT170128 Binding of ITGAL and ITGB2 2 0.04 1.6 0.28 84.84
92 INT119108 Binding of LTBR and TNF 2 0.15 1.47 1.07 84.80
93 INT119107 Negative_regulation of Binding of LTBR and TNF 1 0.17 1.16 0.68 84.80
94 INT119105 Binding of FCGR1A and TNF 1 0.03 1.16 0.67 84.80
95 INT119106 Negative_regulation of Binding of FCGR1A and TNF 1 0.03 1.16 0.67 84.80
96 INT107937 POMC Regulation of Gene_expression of TGFBR2 1 0.28 0.82 0.81 84.80
97 INT186355 Il23a Positive_regulation of Gene_expression of Il17a 4 0.12 3 1.24 84.40
98 INT285561 Il23a Positive_regulation of Gene_expression of Il22 2 0.06 2.45 0.93 84.40
99 INT285570 Binding of IL8 and Cdkn1c 1 0.11 0.76 0.34 84.00
100 INT311997 Regulation of STAM Regulation of BGLAP 1 0.00 0.61 0.32 83.88
101 INT311991 STAM Regulation of BGLAP 1 0.00 0.61 0.31 83.24
102 INT168256 Binding of MLL and TNFRSF1B 1 0.00 1.2 0.53 83.20
103 INT130721 Binding of IL1B and IL1RN 6 0.05 5.29 2.85 83.00
104 INT285467 Negative_regulation of Binding of IL1B and IL1RN 1 0.05 1.33 0.61 83.00
105 INT274156 Negative_regulation of Cabin1 Negative_regulation of Gene_expression of Vegfa 1 0.08 0.28 0.09 82.32
106 INT168416 MIR146A Regulation of Irak1 1 0.24 0.99 0.59 81.40
107 INT289957 Binding of APCS and CD58 1 0.04 0.35 0.08 80.32
108 INT289956 Binding of APC and ICAM1 1 0.04 0.5 0.13 79.40
109 INT107938 POMC Positive_regulation of Gene_expression of TGFBR2 1 0.42 1.09 1.07 77.36
110 INT167596 Il23a Positive_regulation of Gene_expression of Ifng 1 0.13 0.94 0.32 77.36
111 INT300855 Il1 Regulation of Il6 1 0.01 0.81 0.3 77.28
112 INT313915 Binding of Il12a and Il23a 2 0.16 0.44 0.31 75.64
113 INT313914 Binding of Il12a and Il23r 1 0.14 0.44 0.13 75.64
114 INT150393 Binding of CASP1 and MEFV 2 0.16 2.48 0.45 75.60
115 INT77988 Binding of F13A1 and F13a1 1 0.01 1.44 0.33 75.00
116 INT313913 Binding of Il23a and Il23r 1 0.24 0.43 0.13 75.00
117 INT334879 CASP1 Regulation of IL1B 1 0.03 1.63 0.31 74.40
118 INT71176 Binding of ICAM1 and ITGB2 4 0.21 4.93 1.07 74.20
119 INT277791 Binding of Icam1 and Itgal 1 0.03 0.37 0.17 74.20
120 INT131156 Binding of RUNX1 and TNF 2 0.03 3.44 1.42 73.68
121 INT184955 EGR1 Regulation of Regulation of TGFB1 1 0.39 0.3 0 73.40
122 INT320121 Binding of PTEN and TNF 1 0.05 0.76 0.49 73.36
123 INT226340 Binding of CD4 and IFNA1 3 0.03 3.84 0.85 71.76
124 INT219153 IL6 Positive_regulation of IL23A 1 0.02 0.45 0.21 71.52
125 INT243678 Binding of GSR and Ugcg 2 0.03 2.84 0.83 71.36
126 INT246024 IL23A Positive_regulation of SOCS2 1 0.01 0.99 0.43 71.20
127 INT246023 IL6 Positive_regulation of SOCS2 1 0.18 0.99 0.43 71.20
128 INT266417 Binding of TGM2 and S100a11 1 0.01 0.86 0.16 70.40
129 INT278156 Negative_regulation of Trib3 Negative_regulation of Akt1 1 0.00 0.45 0.1 67.72
130 INT266377 Binding of S100a11 and Trp53 1 0.02 0.89 0.15 65.28
131 INT164517 CABIN1 Positive_regulation of Transcription of IL2 1 0.13 0.35 0.22 65.04
132 INT299789 IL4 Negative_regulation of Gene_expression of RAE1 1 0.00 0.84 0.41 64.80
133 INT299786 IL4 Negative_regulation of Gene_expression of CD5 1 0.07 0.82 0.4 64.80
134 INT307769 TNF Regulation of Gene_expression of Csf2 1 0.03 0.5 0.14 64.64
135 INT307771 TNF Negative_regulation of Gene_expression of Csf2 1 0.03 0.5 0.14 64.64
136 INT307755 TNF Regulation of Gene_expression of IL8 1 0.02 0.5 0.14 64.64
137 INT252294 TNF Regulation of Gene_expression of Il6 2 0.16 1.28 0.49 64.64
138 INT252296 TNF Regulation of Gene_expression of Il1 2 0.03 1.28 0.49 64.64
139 INT299763 Binding of APC and CTLA4 Positive_regulation of Ido1 1 0.11 0.31 0.14 64.28
140 INT299754 Binding of APC and CTLA4 2 0.08 0.97 0.11 64.28
141 INT285940 Binding of IL6 and IL17A 1 0.11 1.42 0.53 63.80
142 INT177978 Binding of CSF1R and SNRNP70 1 0.02 1.49 0.28 63.68
143 INT188692 Binding of Cd40 and Cd40lg 32 0.34 22.95 6.62 63.56
144 INT133021 IRF6 Positive_regulation of Gene_expression of IL8 1 0.11 0.51 0.32 62.32
145 INT311990 FCGR3B Regulation of STAM 1 0.01 0.27 0.09 61.96
146 INT325027 Apoc3 Negative_regulation of Pnlip 1 0.01 1.02 0.04 61.36
147 INT209957 Binding of CD8A and RDBP Positive_regulation of CD8A 1 0.01 0.3 0.71 60.80
148 INT209956 Binding of CD8A and RDBP 1 0.01 0.3 0.7 60.80
149 INT299766 APCS Positive_regulation of Gene_expression of Cd80 1 0.04 0.86 0.5 60.68
150 INT299767 APCS Positive_regulation of Gene_expression of Cd86 1 0.07 0.86 0.5 60.68
151 INT299764 APCS Positive_regulation of Cd86 1 0.02 0.86 0.5 60.68
152 INT299765 APCS Positive_regulation of Cd80 1 0.04 0.85 0.49 60.68
153 INT182150 Binding of APC and DCPS 1 0.02 1.14 0.48 59.72
154 INT225262 Egf Regulation of Gene_expression of S100a7a 1 0.04 3.31 0.06 58.56
155 INT325026 Apoc3 Negative_regulation of Lpl 1 0.03 1.01 0.04 58.08
156 INT323710 TRAF6 Regulation of MIR146A 1 0.06 0.55 0.28 57.72
157 INT176477 Binding of CXCR3 and CXCL10 14 0.25 10.61 5.87 55.68
158 INT346217 Braf Positive_regulation of Phosphorylation of Map2k1 1 0.22 3.23 1.72 53.36
159 INT285569 TNF Negative_regulation of Gene_expression of Il6 1 0.03 2.83 1.46 52.56
160 INT275509 IL8 Positive_regulation of Gene_expression of TIMP1 1 0.00 0.85 0.28 52.28
161 INT334061 Negative_regulation of Binding of TNFRSF11A and Tnfsf11 1 0.01 0.52 0.08 52.24
162 INT275554 Binding of CXCL10 and Cxcr3 1 0.03 2.18 0.71 52.00
163 INT275557 Negative_regulation of Binding of CXCL10 and Cxcr3 1 0.04 1.09 0.35 52.00
164 INT295005 Binding of TNFRSF11A and Tnfsf11 3 0.20 2.02 0.09 51.88
165 INT275548 Il10 Regulation of Mmp9 1 0.00 0.86 0.28 51.44
166 INT275556 Il10 Positive_regulation of Gene_expression of TIMP1 1 0.00 0.85 0.28 51.44
167 INT252352 Binding of THBS1 and Sirpa 1 0.00 0.26 0.15 50.52
168 INT263008 Binding of DEFB1 and DEFB103A 1 0.06 0 0 50.00
169 INT323709 MIR146A Negative_regulation of TNF 1 0.12 0.46 0.23 49.20
170 INT252356 Binding of THBS1 and Cd47 1 0.00 0.44 0.24 48.84
171 INT323698 Gene_expression of MIR146A Regulation of FAF1 1 0.16 1.82 0.86 47.36
172 INT329794 TLR2 Positive_regulation of Positive_regulation of IL12A 1 0.01 1.05 0.44 46.92
173 INT329803 TLR2 Positive_regulation of Positive_regulation of IL6 1 0.01 0.94 0.41 46.92
174 INT329800 TLR2 Positive_regulation of Positive_regulation of IL8 1 0.01 0.99 0.41 46.92
175 INT329648 Flt1 Positive_regulation of Positive_regulation of VEGFA 1 0.03 0.58 0 45.64
176 INT244243 Regulation of Binding of IL8 and Ccl3 1 0.04 0.05 0.18 45.48
177 INT244240 Binding of IL8 and Ccr5 1 0.03 0.05 0.18 45.48
178 INT244241 Binding of IL8 and Ccl3 1 0.05 0.05 0.18 45.48
179 INT244242 Negative_regulation of Binding of IL8 and Ccl3 1 0.06 0.05 0.18 45.48
180 INT329168 MAPK8 Positive_regulation of Localization of JUN 1 0.12 0.56 0.15 44.40
181 INT329172 Phosphorylation of MAPK8 Positive_regulation of Localization of JUN 1 0.12 0.62 0.15 44.40
182 INT181450 Binding of Ccr5 and Ccl3 4 0.18 2.19 1.03 43.08
183 INT252330 Binding of Cd36 and Cd47 2 0.10 0.72 0.19 42.68
184 INT122163 Binding of TNF and TNFRSF1B 6 0.44 6.06 2.41 42.44
185 INT252357 Binding of THBS1 and Cd36 2 0.01 2.4 0.21 42.32
186 INT285939 IL6 Positive_regulation of TEP1 1 0.01 1.76 0.61 40.96
187 INT148704 Binding of TNF and TNFRSF1A 5 0.44 3.3 2.09 40.64
188 INT323704 TNF Positive_regulation of Gene_expression of MIR146A 1 0.13 0.97 0.38 38.32
189 INT342886 Binding of C3 and CD40 1 0.02 0.66 0.05 38.04
190 INT321598 Binding of MLL and TNF 1 0.05 1.07 0.49 34.28
191 INT354923 Binding of VDR and Uvbs1 1 0.00 0.83 0 33.44
192 INT342887 Binding of IFNG and IFNGR1 1 0.02 0.65 0.05 33.36
193 INT296038 TGFB1 Positive_regulation of Gene_expression of IL23R 1 0.02 0.05 0.11 32.84
194 INT127143 Binding of IL6 and TGFB1 2 0.01 0.16 0.08 32.84
195 INT296041 Binding of TGFB1 and IL21 1 0.01 0.05 0.08 32.84
196 INT296036 IL6 Positive_regulation of IL17A 1 0.04 0.05 0.17 31.92
197 INT296037 TGFB1 Positive_regulation of IL17A 1 0.02 0 0.17 31.92
198 INT296032 IL6 Positive_regulation of Gene_expression of IL23R 1 0.02 0.05 0.11 31.84
199 INT296035 IL21 Positive_regulation of Gene_expression of IL23R 1 0.01 0.05 0.08 31.48
200 INT209885 TNFSF11 Positive_regulation of TNFRSF11A 3 0.56 3.41 0.55 30.68

Single Events

The table below shows the top 200 pain related interactions that have been reported for Psoriasis. They are ordered first by their pain relevance and then by number of times they were reported in Psoriasis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 100.00
2 INT123142 Gene_expression of DEFB4A 54 0.76 36.14 10.02 100.00
3 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 100.00
4 INT15516 Gene_expression of Crp 711 0.77 615.33 173.09 100.00
5 INT86639 Gene_expression of KRT16 19 0.68 12.44 7.79 100.00
6 INT10832 Gene_expression of IL8 1050 0.78 698.72 270 100.00
7 INT19330 Binding of HLA-A 99 0.48 76.26 22.85 100.00
8 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210 100.00
9 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 100.00
10 INT48066 Binding of CAMP 3 0.36 2.69 0.93 100.00
11 INT9256 Gene_expression of SELPLG 30 0.75 16.44 3.66 100.00
12 INT19472 Gene_expression of Il1 554 0.76 419.75 175.35 100.00
13 INT23402 Binding of HLA-DOA 74 0.48 52.01 10.89 100.00
14 INT263023 Gene_expression of PI3 6 0.75 2.68 1.39 100.00
15 INT63349 Gene_expression of PECAM1 199 0.75 166.03 36.76 100.00
16 INT94408 Positive_regulation of Gene_expression of IFI27 28 0.65 12.89 3.53 100.00
17 INT55758 Positive_regulation of Apoe 15 0.70 11.71 4.69 100.00
18 INT69452 Positive_regulation of SEPHS1 3 0.41 1.41 0.71 100.00
19 INT1873 Gene_expression of MRAP 51 0.76 31.75 13.92 100.00
20 INT263026 Binding of DEFA6 1 0.02 0.54 0.2 100.00
21 INT46405 Negative_regulation of Gene_expression of ATN1 1 0.41 2.58 0.69 100.00
22 INT46402 Negative_regulation of Gene_expression of DONSON 1 0.04 2.58 0.69 100.00
23 INT46401 Negative_regulation of ATN1 1 0.41 2.57 0.69 100.00
24 INT46410 Negative_regulation of DONSON 1 0.04 2.57 0.69 100.00
25 INT46404 Negative_regulation of NDUFA5 1 0.18 2.57 0.69 100.00
26 INT203186 Localization of DYX1 1 0.03 0.73 0.33 100.00
27 INT597 Positive_regulation of PON1 26 0.62 19.14 2.87 100.00
28 INT168263 Gene_expression of IL23A 57 0.58 47.1 17.67 99.96
29 INT188776 Positive_regulation of IFIH1 10 0.23 9.93 0.35 99.96
30 INT49404 Binding of Itgal 11 0.36 9.16 1.53 99.96
31 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98 99.92
32 INT174117 Gene_expression of Cd1d1 26 0.75 12.07 3.07 99.92
33 INT17686 Negative_regulation of Hdl1 72 0.36 81.85 7.74 99.92
34 INT36287 Binding of CD4 96 0.47 58.93 11.88 99.92
35 INT150022 Positive_regulation of Il17a 69 0.64 70.04 21.87 99.92
36 INT219181 Negative_regulation of ITGA1 1 0.05 1.34 0.32 99.92
37 INT325023 Negative_regulation of Regulation of Hdl1 1 0.10 1.61 0.14 99.92
38 INT212966 Negative_regulation of Gene_expression of Hdl1 8 0.27 10.98 0.49 99.92
39 INT201084 Localization of HLA-C 2 0.73 1.04 0.3 99.92
40 INT52264 Gene_expression of IK 180 0.77 90.87 51.87 99.88
41 INT5058 Positive_regulation of IFNA1 356 0.70 245.75 60.52 99.88
42 INT108480 Gene_expression of CCL21 53 0.77 37.87 14.42 99.86
43 INT226463 Positive_regulation of IL23A 23 0.45 21.58 9.18 99.84
44 INT296054 Positive_regulation of Il22 13 0.33 17.97 4.06 99.84
45 INT159631 Positive_regulation of DCPS 60 0.27 43.23 10.3 99.84
46 INT60526 Gene_expression of IL10 449 0.78 292.71 107.84 99.84
47 INT112967 Regulation of Mcpt1 15 0.54 13.03 8.58 99.84
48 INT44156 Regulation of Scl1 1 0.00 0.91 0.46 99.84
49 INT118817 Positive_regulation of Apoc4 6 0.45 6.44 1.23 99.84
50 INT49995 Positive_regulation of Gene_expression of Tnf 187 0.70 125.07 70.54 99.84
51 INT261227 Gene_expression of Impact 3 0.20 2.38 0.37 99.84
52 INT80420 Gene_expression of IFI27 145 0.78 63.61 8.83 99.84
53 INT97131 Positive_regulation of CD14 25 0.67 12.03 4.21 99.84
54 INT84367 Gene_expression of S100a7a 2 0.15 25.36 1.16 99.84
55 INT186622 Negative_regulation of Chol1 9 0.42 3.86 0.32 99.84
56 INT174118 Regulation of Gene_expression of Cd1d1 1 0.44 1.42 0.4 99.84
57 INT63169 Positive_regulation of Gene_expression of Selp 35 0.69 21.95 7.16 99.84
58 INT155006 Regulation of RETN 9 0.45 7.31 1.7 99.84
59 INT261226 Negative_regulation of Impact 1 0.07 0.73 0.33 99.84
60 INT51017 Positive_regulation of Icam1 113 0.70 81.16 35.55 99.84
61 INT70050 Negative_regulation of IL10 56 0.58 37.45 12.39 99.84
62 INT174420 Positive_regulation of Gene_expression of Cd74 3 0.20 1.92 0.81 99.84
63 INT167039 Gene_expression of Cd74 24 0.40 17.12 2.84 99.84
64 INT18954 Negative_regulation of OLAH 9 0.09 8.31 3.67 99.84
65 INT6489 Positive_regulation of Gene_expression of Tnf 140 0.70 92.31 67.85 99.84
66 INT6486 Positive_regulation of Tnf 168 0.70 123.47 66.05 99.84
67 INT11235 Positive_regulation of IFNA2 27 0.69 15.32 2.57 99.84
68 INT174418 Regulation of Gene_expression of Cd74 1 0.04 0.9 0.46 99.84
69 INT180526 Regulation of S100A9 3 0.41 3.21 0.34 99.84
70 INT222742 Regulation of S100A12 4 0.53 12.09 3.03 99.84
71 INT207852 Positive_regulation of Olr1 9 0.12 9.76 2.26 99.82
72 INT9408 Positive_regulation of Crp 296 0.69 242.27 57.35 99.82
73 INT111377 Positive_regulation of Ifih1 16 0.60 11.22 6.99 99.82
74 INT172171 Gene_expression of IL15 47 0.37 46.23 13.41 99.82
75 INT10838 Positive_regulation of IL8 381 0.70 295.51 101.62 99.80
76 INT118095 Regulation of COMP 7 0.43 9.69 3.33 99.80
77 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 99.80
78 INT12720 Positive_regulation of Il1 246 0.70 195.97 72.05 99.80
79 INT93948 Negative_regulation of Gene_expression of Il12a 48 0.55 27.77 16.87 99.80
80 INT16303 Negative_regulation of Localization of GH1 89 0.59 37.31 22.15 99.80
81 INT67822 Binding of SERPINH1 17 0.36 19.05 7.24 99.80
82 INT252 Localization of GH1 529 0.80 227.4 122.05 99.80
83 INT235510 Binding of Il17a 14 0.34 10.67 3.99 99.78
84 INT131160 Negative_regulation of Binding of CD58 2 0.15 1.83 0.53 99.78
85 INT131159 Negative_regulation of Binding of Cd2 1 0.23 1.38 0.19 99.78
86 INT47517 Binding of Bw16 1 0.16 0.92 0.63 99.76
87 INT146300 Binding of RS1 31 0.22 29.55 3.04 99.76
88 INT10173 Binding of Tnf 45 0.48 35.6 14.32 99.74
89 INT118381 Gene_expression of Il17a 405 0.76 306.97 112.06 99.72
90 INT133028 Gene_expression of TLR2 209 0.73 131.92 36.17 99.72
91 INT133030 Positive_regulation of Gene_expression of TLR2 53 0.65 38.15 10.65 99.72
92 INT111476 Gene_expression of TP63 88 0.76 61.08 11.64 99.72
93 INT222903 Gene_expression of TLR1 20 0.60 8.77 1.9 99.72
94 INT46409 Gene_expression of NDUFA5 2 0.29 4.76 1.18 99.72
95 INT242887 Positive_regulation of Gene_expression of TLR1 2 0.28 1.87 0.49 99.72
96 INT56286 Binding of HLA-DRB6 2 0.01 2.12 0.52 99.72
97 INT74818 Transcription of KNG1 6 0.67 2.71 1.59 99.70
98 INT8357 Gene_expression of KNG1 153 0.75 77.26 68.66 99.70
99 INT5116 Gene_expression of IL2 670 0.78 291.13 146.69 99.68
100 INT7336 Positive_regulation of VIP 60 0.70 24.2 19.62 99.68
101 INT61619 Gene_expression of IL12A 194 0.77 146.07 41.97 99.68
102 INT31582 Gene_expression of Hdl1 103 0.66 118.95 6.42 99.68
103 INT171117 Binding of Itgam 35 0.36 14.87 2.76 99.68
104 INT70860 Binding of SNRPB 17 0.35 7 1.46 99.68
105 INT82828 Positive_regulation of COMP 45 0.61 35.12 6.2 99.64
106 INT621 Positive_regulation of SERPINH1 19 0.57 21.52 8.44 99.64
107 INT181886 Gene_expression of Apoa1 40 0.64 40.53 4.56 99.64
108 INT10827 Gene_expression of Apob 16 0.78 13.08 0.9 99.64
109 INT190882 Regulation of Gene_expression of Apoa1 4 0.23 3.67 0.43 99.64
110 INT325024 Regulation of Gene_expression of Apoa2 1 0.21 1.23 0.03 99.64
111 INT325018 Regulation of Gene_expression of Apob 2 0.16 1.59 0.03 99.64
112 INT174753 Gene_expression of Apoa2 15 0.75 13.82 0.41 99.64
113 INT49214 Gene_expression of Cd4 269 0.78 154.22 34.05 99.62
114 INT217388 Negative_regulation of Gene_expression of Apoe 11 0.59 6.07 1.4 99.62
115 INT77945 Regulation of Gene_expression of Il12a 19 0.58 6.55 6.4 99.62
116 INT306723 Binding of Il22 3 0.11 2.44 0.97 99.58
117 INT11624 Gene_expression of OPRM1 445 0.78 72.36 294.36 99.56
118 INT76863 Negative_regulation of Gene_expression of OPRM1 21 0.57 6.56 13.69 99.56
119 INT131161 Binding of CD58 5 0.17 3.54 1.03 99.56
120 INT46435 Gene_expression of NDUFB6 1 0.65 2.21 0.49 99.56
121 INT14600 Positive_regulation of Tpsab1 51 0.68 22.1 7.7 99.54
122 INT9660 Regulation of TNF 363 0.62 312.94 139.99 99.52
123 INT867 Gene_expression of IFNA1 930 0.78 594.85 168.03 99.52
124 INT80806 Gene_expression of PDC 12 0.75 4.34 5.73 99.52
125 INT174428 Positive_regulation of Cxcr1 8 0.53 8.1 4.79 99.52
126 INT299802 Negative_regulation of Transcription of IFNA1 2 0.09 0.54 0.41 99.52
127 INT107307 Transcription of IFNA1 30 0.52 18.16 9.61 99.52
128 INT99785 Positive_regulation of Cxcr2 10 0.53 8.03 4.89 99.52
129 INT174444 Positive_regulation of Transcription of Cxcr1 1 0.36 0.79 0.42 99.52
130 INT175312 Positive_regulation of Gene_expression of IL23A 17 0.45 14.8 5.05 99.50
131 INT306735 Positive_regulation of Positive_regulation of IL23A 4 0.26 3.25 1.04 99.50
132 INT113985 Positive_regulation of TP63 9 0.50 8.79 1.62 99.50
133 INT306741 Positive_regulation of Positive_regulation of TP63 2 0.05 1.16 0.49 99.50
134 INT60691 Gene_expression of Il12a 331 0.78 208.03 75.96 99.48
135 INT48406 Gene_expression of Icam1 277 0.78 238.28 81.71 99.48
136 INT49487 Gene_expression of Sele 65 0.76 68.11 19.41 99.48
137 INT230086 Negative_regulation of Localization of IFN1@ 9 0.57 6.06 1.25 99.48
138 INT28265 Positive_regulation of Calca 62 0.70 29.1 41.17 99.48
139 INT2289 Gene_expression of PENK 203 0.78 55.62 79.49 99.48
140 INT63975 Positive_regulation of Il10 175 0.68 134.13 54.69 99.48
141 INT85426 Transcription of CSPG4 1 0.23 1.03 0.3 99.48
142 INT53574 Regulation of Tnf 45 0.62 40.68 19.71 99.48
143 INT160241 Negative_regulation of Positive_regulation of Il10 6 0.39 6.33 1.92 99.48
144 INT6481 Binding of TNF 624 0.48 510.2 214.82 99.44
145 INT170754 Localization of IFN1@ 121 0.78 66.78 15.6 99.44
146 INT103757 Negative_regulation of Il12a 37 0.55 21.62 16.38 99.44
147 INT45142 Gene_expression of DCPS 109 0.56 84.71 16.87 99.44
148 INT250888 Negative_regulation of IL23A 4 0.30 6.13 2.15 99.44
149 INT95565 Positive_regulation of IL12A 47 0.56 33.96 10.16 99.44
150 INT190387 Regulation of DEFB4A 4 0.42 3.95 1.27 99.44
151 INT167478 Positive_regulation of Gene_expression of DCPS 23 0.27 14.75 3.37 99.44
152 INT54234 Binding of Cd2 6 0.35 2.14 1.99 99.44
153 INT46406 Binding of DONSON 1 0.03 2.54 0.68 99.42
154 INT46408 Gene_expression of DONSON 1 0.06 2.54 0.68 99.42
155 INT125138 Positive_regulation of RETN 13 0.67 11.94 2.34 99.42
156 INT3841 Gene_expression of FCGR3B 117 0.75 58.99 28.87 99.40
157 INT3839 Positive_regulation of Gene_expression of FCGR3B 10 0.67 13.58 6.25 99.40
158 INT86641 Regulation of Gene_expression of KRT16 1 0.40 0.42 0.74 99.40
159 INT82398 Binding of HLA-DMB 3 0.35 3.82 1.66 99.40
160 INT9158 Gene_expression of Tnf 722 0.78 522.01 277.68 99.38
161 INT263020 Regulation of DEFB103A 1 0.20 1.22 0.47 99.38
162 INT10828 Regulation of Apob 7 0.39 7.55 0.83 99.36
163 INT12163 Positive_regulation of OLAH 8 0.68 6.91 1.67 99.36
164 INT80419 Gene_expression of Kdm5d 50 0.62 22.49 6.1 99.36
165 INT58904 Localization of TH1L 40 0.68 27.11 10.52 99.34
166 INT244123 Localization of Defa1 5 0.78 3.42 1.23 99.34
167 INT186914 Localization of DEFB1 4 0.78 1.27 0.44 99.34
168 INT636 Binding of MRAP 54 0.48 40.36 18.77 99.32
169 INT251820 Binding of PDC 4 0.28 2.37 0.68 99.32
170 INT116861 Gene_expression of Apoe 182 0.78 100.41 27.26 99.32
171 INT17049 Localization of CD4 57 0.75 35.33 6.89 99.32
172 INT172055 Positive_regulation of Binding of MRAP 1 0.33 1.69 0.84 99.32
173 INT190883 Gene_expression of Apoc3 16 0.38 14.18 1.93 99.32
174 INT24332 Regulation of Hdl1 28 0.45 45.45 4.26 99.32
175 INT467 Gene_expression of POMC 1048 0.78 332.8 394.16 99.32
176 INT7527 Gene_expression of SLTM 12 0.25 2.9 6.07 99.32
177 INT38056 Localization of Crp 71 0.78 53.14 17.03 99.30
178 INT82829 Gene_expression of COMP 104 0.78 57 9.81 99.28
179 INT200470 Positive_regulation of Gene_expression of COMP 13 0.69 13.73 2.93 99.28
180 INT744 Positive_regulation of PTH 130 0.70 95.02 11.7 99.28
181 INT7692 Positive_regulation of PENK 71 0.70 20.34 32.54 99.28
182 INT46407 Binding of ATN1 4 0.36 5.85 1.81 99.26
183 INT46403 Gene_expression of ATN1 2 0.75 3.33 0.93 99.26
184 INT115386 Gene_expression of Ppara 779 0.77 549.99 128.36 99.24
185 INT122039 Positive_regulation of Gene_expression of Ppara 144 0.68 113.55 28.55 99.24
186 INT329189 Gene_expression of RARRES2 1 0.27 1 0.33 99.24
187 INT111155 Positive_regulation of G0s2 9 0.46 9.54 1.53 99.24
188 INT9257 Positive_regulation of SELPLG 5 0.45 3.57 1.16 99.24
189 INT82354 Positive_regulation of PECAM1 25 0.34 22.93 4.69 99.24
190 INT162398 Regulation of LCE3A 1 0.43 2.11 0.93 99.22
191 INT207583 Negative_regulation of RETN 13 0.43 6.97 1.05 99.22
192 INT81722 Regulation of Gene_expression of FCGR3B 5 0.44 3.42 2.47 99.20
193 INT160564 Gene_expression of Il22 64 0.55 59.29 20.9 99.16
194 INT135411 Gene_expression of Il23a 76 0.72 72.87 26.15 99.16
195 INT34644 Binding of HLA-C 19 0.47 9.41 2.2 99.16
196 INT189092 Gene_expression of Tap1 56 0.76 14.09 1.33 99.16
197 INT263017 Positive_regulation of Gene_expression of PI3 2 0.45 0.82 0.26 99.16
198 INT11699 Binding of HLA-E 85 0.47 52.51 13.41 99.16
199 INT146524 Negative_regulation of AADAC 5 0.04 4.2 0.28 99.16
200 INT18311 Positive_regulation of CD8A 145 0.69 113.48 19.44 99.14
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