D:Pulmonary Disease

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pChart

Disease Term
Synonyms Chronic Obstructive Lung Disease, CHRONIC OBSTRUCTIVE PULMONARY DISEASE, Copd, Disease Lung, Disease Pulmonary, Diseases Lung, Diseases Pulmonary, Lung Disease, LUNG DISEASES, Lung Lung Disorder Nos, Pneumopathy
Documents 3499
Hot Single Events 200
Hot Interactions 147

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Pulmonary Disease. They are ordered first by their relevance to Pulmonary Disease and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT219686 Binding of CEL and COPD 1 0.12 11.35 1.26 100.00
2 INT219685 Binding of MMP12 and COPD 1 0.27 5.59 0.74 100.00
3 INT263100 Binding of EFS and COPD 1 0.14 4.14 0.07 100.00
4 INT219684 Binding of MMP12 and GOPC 1 0.09 3.11 0.38 100.00
5 INT219683 Binding of CEL and GOPC 1 0.04 3.11 0.38 100.00
6 INT306794 Binding of LEP and COPD 1 0.15 3.94 0.09 100.00
7 INT259637 Binding of Mmp12 and COPD 2 0.02 1.71 0.4 100.00
8 INT337536 Binding of Klrk1 and COPD 1 0.03 3.09 0.09 100.00
9 INT315194 Binding of SFRP1 and Slc10a1 1 0.02 8.85 0 100.00
10 INT269013 Binding of CSRP1 and COPD 1 0.08 1.3 0.11 100.00
11 INT221910 Binding of SRI and COPD 1 0.01 1.27 0 100.00
12 INT315187 Binding of SFRP1 and COPD 1 0.01 4.47 0 100.00
13 INT233401 COPD Regulation of HEY1 1 0.07 1.67 0 100.00
14 INT233400 COPD Regulation of CRH 1 0.11 1.67 0 100.00
15 INT259636 Binding of Tbce and COPD 1 0.04 1 0.11 100.00
16 INT335446 Binding of PDX1 and COPD 1 0.02 1.99 0.3 100.00
17 INT224150 Binding of TREM1 and COPD 1 0.07 0.7 0.05 100.00
18 INT272867 Binding of NLRP1 and COPD 1 0.00 1.07 0 100.00
19 INT263176 Binding of PDE4A and COPD 1 0.01 1 0.15 100.00
20 INT263179 PDE3A Regulation of COPD 1 0.00 1 0.15 100.00
21 INT263177 Binding of PDE3A and COPD 1 0.01 1 0.15 100.00
22 INT263180 Binding of PDE5A and COPD 1 0.01 1 0.15 100.00
23 INT263175 PDE5A Regulation of COPD 1 0.00 1 0.15 100.00
24 INT263178 Binding of PDE7A and COPD 1 0.01 1 0.15 100.00
25 INT263174 PDE7A Regulation of COPD 1 0.01 1 0.15 100.00
26 INT335447 PDX1 Regulation of Gene_expression of COPD 1 0.02 1.03 0.24 100.00
27 INT275555 Binding of Ltb4r1 and COPD 1 0.01 1.02 0.3 100.00
28 INT191900 Binding of EXOSC10 and COPD 1 0.01 0.53 0 100.00
29 INT269014 Binding of EGR1 and COPD 1 0.12 0.96 0 100.00
30 INT272930 Positive_regulation of Binding of Mmp1a and COPD 1 0.01 0.79 0.29 100.00
31 INT272929 Positive_regulation of Binding of Mmp9 and COPD 1 0.01 0.79 0.29 100.00
32 INT272928 Positive_regulation of Binding of Mmp12 and COPD 1 0.01 0.79 0.29 100.00
33 INT272933 Binding of Mmp1a and COPD 1 0.01 0.78 0.29 100.00
34 INT272932 Binding of Mmp9 and COPD 1 0.01 0.78 0.29 100.00
35 INT310939 Binding of ELANE and COPD 1 0.08 1.51 0.2 100.00
36 INT259638 COPD Positive_regulation of NFE2L2 1 0.03 1.31 0.05 100.00
37 INT259633 Mmp9 Positive_regulation of Gene_expression of COPD 1 0.01 0.92 0.17 100.00
38 INT259634 Elane Positive_regulation of Gene_expression of COPD 1 0.01 0.92 0.17 100.00
39 INT193204 Binding of TMED4 and COPD 1 0.02 0.29 0 100.00
40 INT310937 Binding of CD8A and COPD 1 0.16 1.21 0.16 100.00
41 INT273197 Binding of BCR and COPD 1 0.03 0.4 0 100.00
42 INT261597 Binding of PAH and COPD 1 0.00 1.08 0.34 100.00
43 INT344135 Negative_regulation of Binding of Col7a1 and Lhyp 1 0.00 0.5 0.13 100.00
44 INT344134 Binding of Col7a1 and Lhyp 1 0.00 0.5 0.13 100.00
45 INT175393 Binding of Ugcg and Ssr1 1 0.04 0.6 0.03 99.68
46 INT263049 Positive_regulation of Binding of Mmp2 and Mmp9 1 0.35 0.83 0.69 99.64
47 INT274170 Il13 Regulation of Il4 3 0.09 2.75 0.51 99.62
48 INT336926 Mir341 Regulation of Tlr4 1 0.02 1.57 0.41 99.52
49 INT273353 Pde4d Regulation of Gene_expression of Twist1 1 0.26 0.25 0.05 99.52
50 INT274167 Il13 Regulation of Il5 2 0.09 2.05 0.59 99.50
51 INT221383 Tlr4 Positive_regulation of Localization of Ptger2 1 0.00 1.78 0.23 99.48
52 INT221386 Tlr4 Positive_regulation of Gene_expression of IL8 6 0.14 3.53 0.9 99.44
53 INT221387 Tlr4 Positive_regulation of Localization of IL8 1 0.05 2.98 0 99.24
54 INT335457 Binding of SRA1 and hb 1 0.00 1.83 0.37 99.24
55 INT27759 Calca Regulation of Sct 1 0.00 0.9 0.08 99.24
56 INT221385 Tlr4 Positive_regulation of IL8 1 0.05 1.79 0.2 99.16
57 INT102160 Binding of Mmp2 and Mmp9 3 0.28 2.87 1.75 99.04
58 INT190183 MAPK1 Regulation of CDCP1 1 0.00 1.19 0.85 98.92
59 INT221382 Tlr4 Positive_regulation of Localization of Ltb4r1 1 0.01 1.38 0.14 98.88
60 INT310938 Binding of ELANE and HRCT1 1 0.02 1.5 0.2 98.84
61 INT275554 Binding of CXCL10 and Cxcr3 1 0.03 2.18 0.71 98.76
62 INT275557 Negative_regulation of Binding of CXCL10 and Cxcr3 1 0.04 1.09 0.35 98.76
63 INT190168 BSG Regulation of CDCP1 1 0.00 1.18 0.84 98.72
64 INT221368 EGFR Regulation of Gene_expression of MUC1 1 0.05 3.82 0.06 98.64
65 INT272951 Binding of TNF and Igf1 1 0.14 1.48 0.36 98.52
66 INT272953 Negative_regulation of Binding of TNF and Igf1 1 0.16 1.48 0.36 98.52
67 INT274168 Egf Positive_regulation of Gene_expression of Muc5ac 1 0.01 2.11 0.17 98.24
68 INT185384 IRF6 Regulation of Gene_expression of CD14 1 0.04 0.99 0 97.96
69 INT275553 Negative_regulation of Binding of Ccr5 and Ccl3 1 0.05 0.73 0.26 97.88
70 INT181450 Binding of Ccr5 and Ccl3 4 0.18 2.19 1.03 97.88
71 INT244232 Binding of Ccr5 and Ccl4 3 0.17 1.48 0.55 97.88
72 INT272852 Binding of SLI2 and IAH1 1 0.05 0.25 0.05 97.84
73 INT274172 Negative_regulation of Pde4a Negative_regulation of Positive_regulation of TNF 1 0.02 0.72 0.28 97.28
74 INT244461 CS Positive_regulation of ESR1 1 0.06 1.15 0.05 96.56
75 INT349659 PYCARD Positive_regulation of ADRB2 1 0.06 0.19 0.17 96.44
76 INT272952 Igf1 Positive_regulation of Localization of TNF 1 0.19 1.53 0.35 96.28
77 INT332251 Il13 Positive_regulation of Stat1 1 0.14 1.4 0.18 95.88
78 INT349668 Binding of HRH1 and PYCARD 1 0.00 0.37 0.21 95.72
79 INT336925 Aggf1 Positive_regulation of Mir341 1 0.00 0.8 0.21 95.56
80 INT259628 Cxcl10 Positive_regulation of Protein_catabolism of Ecm1 1 0.00 0.64 0.15 95.52
81 INT190173 BSG Regulation of MMRN1 1 0.00 0.29 0.35 95.20
82 INT335458 hb Positive_regulation of SRA1 1 0.00 0.87 0.25 95.08
83 INT335456 Binding of PDX1 and hb 1 0.02 2.59 0.66 94.96
84 INT335455 Negative_regulation of Binding of PDX1 and hb 1 0.02 1.3 0.33 94.96
85 INT191899 Binding of EXOSC10 and PNN 1 0.00 0.96 0.03 94.32
86 INT169403 Binding of TRPV1 and Trpv4 1 0.23 0.94 0.05 94.32
87 INT272931 Binding of IL8 and Cxcr1 1 0.07 0.65 0.18 94.20
88 INT203759 Binding of EDN1 and TNF 1 0.16 0.71 0.16 93.60
89 INT176477 Binding of CXCR3 and CXCL10 14 0.25 10.61 5.87 93.20
90 INT203758 Binding of IL6 and TNF 3 0.26 2.03 0.67 93.04
91 INT259627 Cxcl10 Positive_regulation of Gene_expression of Mmp12 1 0.02 0.64 0.15 92.96
92 INT275548 Il10 Regulation of Mmp9 1 0.00 0.86 0.28 92.80
93 INT275552 Tlr4 Positive_regulation of Gene_expression of Il1 1 0.00 1.28 0.59 92.56
94 INT226380 Gene_expression of IL15 Negative_regulation of Positive_regulation of CD8A 1 0.02 1.59 0.18 91.72
95 INT275509 IL8 Positive_regulation of Gene_expression of TIMP1 1 0.00 0.85 0.28 91.64
96 INT284570 Binding of Avp and Il6 1 0.04 2.17 0.13 91.44
97 INT190167 Binding of JUN and MMP12 1 0.26 0.82 2.76 91.28
98 INT190145 Binding of JUN and MMP12 Positive_regulation of Positive_regulation of PIK3CA 1 0.01 0.57 0.57 91.28
99 INT190146 Positive_regulation of PIK3CA Positive_regulation of Binding of JUN and MMP12 1 0.01 0.57 0.57 91.28
100 INT190148 Binding of JUN and MMP12 Positive_regulation of MMP12 1 0.33 0.57 0.57 91.28
101 INT337535 HLA-DRB1 Positive_regulation of Trav6-3 1 0.00 1.14 0.04 91.04
102 INT336835 Binding of CACNG6 and Aia1 1 0.01 3.41 0.75 90.84
103 INT275556 Il10 Positive_regulation of Gene_expression of TIMP1 1 0.00 0.85 0.28 90.80
104 INT261609 Binding of PAH and Hypt 1 0.00 1.26 0.28 90.40
105 INT178723 Binding of ALB and TNNI3 1 0.17 0.91 0 89.84
106 INT288538 Il2 Positive_regulation of Gene_expression of Bcl2 1 0.04 1.96 0.03 89.80
107 INT272925 Ccl2 Positive_regulation of Gene_expression of Col7a1 1 0.00 0.72 0.3 89.76
108 INT303691 KNG1 Positive_regulation of AHR 1 0.03 0.98 0.69 89.08
109 INT303689 Regulation of KNG1 Positive_regulation of AHR 1 0.03 0.99 0.69 89.08
110 INT272927 Mapk14 Positive_regulation of Gene_expression of TNF 1 0.16 0.53 0.14 88.88
111 INT271478 Tacr1 Regulation of Binding of Mthfd1 1 0.09 0.48 0.13 88.56
112 INT259623 Binding of Eln and Elane 1 0.02 1.38 0.23 88.44
113 INT179937 Trib3 Regulation of TNF 1 0.00 0.59 0.2 88.16
114 INT190181 Positive_regulation of PIK3CA Positive_regulation of MMP12 1 0.01 0.54 0.56 87.60
115 INT337537 Binding of MICA and Positive_regulation of Klrk1 1 0.07 0.68 0 87.52
116 INT173059 Binding of KDR and VEGFA 43 0.43 29.63 1.1 87.28
117 INT191718 Binding of FLT1 and VEGFA 35 0.50 12.18 0.27 87.28
118 INT173053 Binding of VEGFA and NRP2 3 0.12 1.36 0.04 87.28
119 INT315913 VEGFA Regulation of KDR 1 0.03 0.32 0.04 87.28
120 INT315915 VEGFA Regulation of NRP1 1 0.22 0.32 0.04 87.28
121 INT173051 Binding of VEGFA and NRP1 16 0.44 1.29 0.04 87.28
122 INT315914 VEGFA Regulation of FLT1 1 0.05 0.32 0.04 87.28
123 INT315912 VEGFA Regulation of NRP2 1 0.04 0.32 0.04 87.28
124 INT193033 Binding of CHRM1 and EGF 1 0.01 1.96 0.22 87.20
125 INT288537 Binding of Ccr3 and Ccl11 1 0.17 2.92 0.35 87.04
126 INT346957 HDAC9 Positive_regulation of Gene_expression of GSR 1 0.03 1.28 0.27 86.72
127 INT332250 Stat6 Positive_regulation of Gene_expression of Pdgfa 1 0.05 1.33 0.12 86.72
128 INT332252 Stat6 Positive_regulation of Gene_expression of Il13 1 0.08 1.32 0.12 86.08
129 INT186729 Csf2 Positive_regulation of PPARA 1 0.06 1.04 0.08 85.76
130 INT186712 INCENP Positive_regulation of PPARA 1 0.01 1.05 0.08 85.76
131 INT302421 IFNA1 Positive_regulation of Cxcl10 1 0.02 1.8 0.45 85.48
132 INT302422 IFNA1 Positive_regulation of Cxcl9 1 0.03 1.81 0.45 85.48
133 INT259621 Serpinc1 Regulation of Gene_expression of Mmp12 1 0.01 0.89 0.03 85.12
134 INT263173 Binding of PDE7A and Prkaca 1 0.01 0.27 0.09 84.40
135 INT135588 Positive_regulation of IKBKE Positive_regulation of NFKB1 1 0.18 1.29 0.48 82.84
136 INT185388 Binding of PVRL1 and TLR2 1 0.15 0.75 0.04 82.80
137 INT185818 SPP1 Positive_regulation of Gene_expression of COL7A1 1 0.10 0.82 0.28 82.72
138 INT135587 IKBKE Positive_regulation of NFKB1 1 0.18 1.28 0.48 82.32
139 INT343719 Nlrp1a Positive_regulation of PAH 1 0.00 1.9 0.04 82.32
140 INT302423 Etohi5 Positive_regulation of IFNA1 1 0.00 1.77 0.44 82.08
141 INT273350 Pde7a Positive_regulation of Localization of Pde4d 1 0.33 1.35 0.49 81.84
142 INT273352 Pde7a Positive_regulation of Localization of Pde4b 1 0.43 0.68 0.24 81.84
143 INT142961 Binding of Nfkb1 and Casp3 1 0.00 1.02 0.11 81.08
144 INT219661 Binding of CYP2D6 and CYP2E1 1 0.30 0.22 0.08 81.00
145 INT273171 PDE4A Regulation of IL8 1 0.05 0.53 0.15 80.88
146 INT311012 SNRPB Positive_regulation of Gene_expression of ROS1 1 0.00 0.27 0 80.72
147 INT306795 Binding of LEP and SFTPD 1 0.08 1.13 0.23 80.56
148 INT273172 Negative_regulation of PDE4A Negative_regulation of Localization of CD4 1 0.11 0.74 0.37 79.56
149 INT300652 Ephb6 Regulation of Gene_expression of Cxcl10 1 0.01 0.59 0.41 79.36
150 INT259639 MAPK14 Regulation of Gene_expression of IL8 1 0.02 1.2 0.32 79.32
151 INT180928 Binding of Col7a1 and Mmp9 1 0.03 0.96 0.32 79.20
152 INT243044 Mmp8 Regulation of Mmp9 1 0.05 1.45 0.91 78.64
153 INT179935 Binding of Jun and Mapk8 1 0.04 0.61 0.19 78.52
154 INT259670 CSE Positive_regulation of Hmox1 1 0.06 0.97 0 78.00
155 INT70037 TNF Regulation of IL10 2 0.09 2.11 1.26 77.80
156 INT185381 TNF Regulation of TLR2 2 0.31 1.9 0.41 77.80
157 INT99241 IFNG Regulation of IL1B 2 0.21 1.26 0.14 77.80
158 INT185376 IFNG Regulation of IL10 1 0.01 0.69 0.04 77.80
159 INT185383 IL10 Regulation of TLR2 1 0.06 0.68 0.04 77.80
160 INT185377 IL1B Regulation of CSF2 1 0.02 0.68 0.04 77.80
161 INT185380 IFNG Regulation of CSF2 1 0.03 0.69 0.04 77.80
162 INT185378 IL1B Regulation of TLR2 1 0.04 0.68 0.04 77.80
163 INT185374 CSF2 Regulation of TLR2 1 0.04 0.68 0.04 77.80
164 INT185382 IFNG Regulation of TLR2 1 0.09 0.69 0.04 77.80
165 INT185387 TNF Regulation of CSF2 1 0.10 0.69 0.04 77.80
166 INT185375 TNF Regulation of IL1B 1 0.02 0.69 0.04 77.80
167 INT185386 IL10 Regulation of CSF2 1 0.02 0.68 0.04 77.80
168 INT284589 Binding of ICAM1 and Crp 1 0.00 1.08 0.22 77.28
169 INT193034 PRKCA Regulation of Positive_regulation of CDK20 1 0.05 0.15 0.37 76.96
170 INT277656 Igf1 Positive_regulation of Igfbp3 1 0.01 0.4 0.34 76.92
171 INT284552 Binding of Cd8a and Mthfd1 2 0.03 1.32 0.1 76.48
172 INT352547 Binding of CFTR and DMD 1 0.01 1.42 0.35 76.24
173 INT296893 Nps Negative_regulation of Gene_expression of REN 1 0.00 1.05 0.04 75.64
174 INT274169 Mapk1 Regulation of Pde4a 1 0.05 0.62 0.17 75.32
175 INT183695 Binding of Tlr3 and Ducm1 1 0.04 2.75 0.56 74.12
176 INT183700 Binding of Pilra and Ducm1 1 0.00 2.35 0.53 74.12
177 INT185804 MMP2 Positive_regulation of SPP1 1 0.15 0.88 0.37 72.84
178 INT185798 SPP1 Positive_regulation of Gene_expression of MMP2 1 0.26 0.87 0.37 72.84
179 INT317778 Binding of ADRB2 and GOPC 1 0.10 0.69 0 72.64
180 INT191814 PDLIM7 Positive_regulation of TNFRSF8 1 0.08 1.16 0.08 69.88
181 INT191813 PDLIM7 Positive_regulation of FUT4 1 0.09 1.16 0.08 69.88
182 INT259622 Elane Positive_regulation of Protein_catabolism of Ecm1 1 0.00 0.38 0.08 69.76
183 INT231769 TNF Negative_regulation of Gene_expression of HMOX1 1 0.26 4.75 1.15 69.08
184 INT179683 Binding of Col7a1 and Eln 2 0.00 3.02 0.19 68.64
185 INT135586 CSF2 Regulation of ICAM1 1 0.13 1.3 0.49 67.32
186 INT318489 Positive_regulation of IRF6 Negative_regulation of Gene_expression of FPR2 1 0.09 1.18 0.38 67.12
187 INT273185 PDE4A Regulation of Gene_expression of Mmp12 1 0.08 0.57 0.13 66.80
188 INT318482 IRF6 Negative_regulation of Gene_expression of FPR2 1 0.09 1.18 0.38 66.72
189 INT185373 IRF6 Positive_regulation of Gene_expression of TLR2 1 0.08 2.96 1.04 66.68
190 INT185811 SPP1 Positive_regulation of MMP3 1 0.14 0.83 0.38 66.60
191 INT185814 Binding of MMP3 and SPP1 1 0.15 0.83 0.38 66.60
192 INT135584 CSF2 Regulation of PTGS2 1 0.06 1.28 0.49 65.64
193 INT135589 CSF2 Regulation of IL6 1 0.08 1.27 0.48 64.92
194 INT135591 CSF2 Regulation of IL8 1 0.09 1.27 0.48 64.68
195 INT185379 Binding of IRF6 and TLR2 4 0.08 2.88 0.35 64.08
196 INT185385 Binding of TLR2 and TLR4 3 0.27 3.63 0.32 64.08
197 INT182124 Binding of IRF6 and TLR4 14 0.10 16.11 4.65 64.08
198 INT183708 Tlr3 Regulation of Binding of Tlr3 and Ducm1 1 0.02 0.99 0.14 63.36
199 INT284587 Binding of Sele and Aecp 1 0.00 0.3 0.07 63.12
200 INT284586 Positive_regulation of Binding of Sele and Aecp 1 0.00 0.3 0.07 63.12

Single Events

The table below shows the top 200 pain related interactions that have been reported for Pulmonary Disease. They are ordered first by their pain relevance and then by number of times they were reported in Pulmonary Disease. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT147792 Gene_expression of COPD 230 0.70 287.13 24.1 100.00
2 INT70970 Binding of COPD 144 0.42 180.34 18.29 100.00
3 INT125312 Positive_regulation of COPD 134 0.59 162.55 20.27 100.00
4 INT147793 Localization of COPD 70 0.64 89.01 7.3 100.00
5 INT60436 Negative_regulation of COPD 76 0.37 84.22 9.08 100.00
6 INT150867 Regulation of COPD 54 0.48 71.38 8.8 100.00
7 INT10832 Gene_expression of IL8 1050 0.78 698.72 270 100.00
8 INT219695 Positive_regulation of Gene_expression of COPD 24 0.40 33.04 3.42 100.00
9 INT10838 Positive_regulation of IL8 381 0.70 295.51 101.62 100.00
10 INT164189 Gene_expression of TREM1 82 0.62 60.77 5.85 100.00
11 INT78057 Localization of Tlr4 140 0.77 67.75 21.72 100.00
12 INT179688 Negative_regulation of Gene_expression of COPD 13 0.35 16.06 0.97 100.00
13 INT244343 Localization of NTM 16 0.73 14.26 0.26 100.00
14 INT157622 Positive_regulation of Localization of Tlr4 34 0.48 22.63 5.09 100.00
15 INT5454 Localization of CRH 124 0.79 79.18 41.53 100.00
16 INT121333 Localization of HEY1 11 0.65 18.17 0.72 100.00
17 INT179686 Regulation of Gene_expression of COPD 10 0.34 14.1 1.52 100.00
18 INT9349 Gene_expression of BBS2 15 0.49 12.77 4.22 100.00
19 INT224154 Positive_regulation of TREM1 14 0.56 22.65 2.71 100.00
20 INT221384 Positive_regulation of Localization of COPD 6 0.29 9.13 0.75 100.00
21 INT171060 Gene_expression of PDX1 72 0.75 72.57 17.97 100.00
22 INT224151 Positive_regulation of Gene_expression of TREM1 14 0.52 13.04 1.36 100.00
23 INT185398 Negative_regulation of Gene_expression of TLR2 34 0.55 27.21 4.73 100.00
24 INT176618 Gene_expression of HEY1 29 0.59 36 4.37 100.00
25 INT263203 Negative_regulation of Localization of COPD 3 0.36 4.09 0.22 100.00
26 INT179684 Protein_catabolism of COPD 4 0.25 4.25 0.27 100.00
27 INT58527 Gene_expression of Prtn3 20 0.71 15.99 2.9 100.00
28 INT7082 Gene_expression of CRH 180 0.78 64.66 31.74 100.00
29 INT57502 Positive_regulation of Gene_expression of CRH 30 0.70 23.37 5.7 100.00
30 INT187288 Positive_regulation of Gene_expression of HEY1 5 0.17 8.42 0.89 100.00
31 INT187286 Binding of HEY1 17 0.32 31.21 4.52 100.00
32 INT6441 Positive_regulation of CRH 98 0.69 57.22 24.12 100.00
33 INT148384 Positive_regulation of HEY1 19 0.43 29.76 5.89 100.00
34 INT259664 Positive_regulation of Positive_regulation of COPD 3 0.36 4.81 0.37 100.00
35 INT10373 Gene_expression of ADI1 8 0.25 5.97 0.92 100.00
36 INT335454 Negative_regulation of Localization of TFPI 1 0.25 3.24 0.93 100.00
37 INT82434 Positive_regulation of LEP 117 0.70 95.45 20.22 100.00
38 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 100.00
39 INT275343 Positive_regulation of Binding of COPD 2 0.42 3.04 0.33 100.00
40 INT270441 Negative_regulation of Negative_regulation of COPD 3 0.36 4.18 0.23 100.00
41 INT105777 Gene_expression of Pde4a 30 0.76 12.67 8.52 100.00
42 INT263095 Transcription of COPD 3 0.53 2.78 0.33 100.00
43 INT259580 Negative_regulation of Binding of COPD 2 0.10 3.44 0.17 100.00
44 INT335452 Regulation of Gene_expression of PDX1 1 0.05 2.56 0.5 100.00
45 INT96269 Positive_regulation of Mcpt1 71 0.61 52.38 20.4 100.00
46 INT22045 Gene_expression of IRF6 158 0.75 58.07 27.81 100.00
47 INT65356 Localization of LEP 46 0.79 41.17 5.43 100.00
48 INT12087 Regulation of Localization of TNF 44 0.62 28.71 15.17 100.00
49 INT272057 Phosphorylation of COPD 2 0.54 4.15 0.22 100.00
50 INT20611 Gene_expression of Asap1 55 0.65 23.71 14.62 100.00
51 INT242321 Negative_regulation of Gene_expression of Asap1 1 0.20 1.96 0 100.00
52 INT115963 Negative_regulation of Gene_expression of CRH 9 0.59 4.53 1.48 100.00
53 INT187287 Negative_regulation of Gene_expression of HEY1 2 0.16 2.96 0.45 100.00
54 INT134841 Regulation of YAP1 2 0.27 3.02 0.09 100.00
55 INT120074 Regulation of Gene_expression of Smad7 1 0.58 2.05 0.5 100.00
56 INT335453 Negative_regulation of Localization of INTU 1 0.13 1.62 0.47 100.00
57 INT335451 Positive_regulation of Localization of TFPI 1 0.29 1.65 0.48 100.00
58 INT274177 Positive_regulation of Gene_expression of BBS2 2 0.36 1.55 0.49 100.00
59 INT274176 Negative_regulation of Gene_expression of BBS2 1 0.31 0.94 0.29 100.00
60 INT259578 Negative_regulation of Positive_regulation of COPD 1 0.26 1.76 0.41 100.00
61 INT9647 Gene_expression of PROC 163 0.65 89.76 26.75 100.00
62 INT336962 Gene_expression of Asthm1 1 0.00 1.84 0 100.00
63 INT336961 Negative_regulation of Asthm1 1 0.00 2.19 0.17 100.00
64 INT272921 Regulation of Localization of COPD 1 0.19 2.82 0.43 100.00
65 INT272917 Positive_regulation of Negative_regulation of COPD 1 0.05 0.93 0.42 100.00
66 INT169926 Positive_regulation of Gopc 416 0.46 157.8 58.67 100.00
67 INT310949 Regulation of Positive_regulation of COPD 1 0.32 1.59 0.5 100.00
68 INT25223 Positive_regulation of Gene_expression of IFNG 41 0.67 36.97 15.89 100.00
69 INT66423 Binding of ELOVL1 52 0.40 61.63 5.16 100.00
70 INT72564 Localization of Il10 41 0.78 28.62 17.6 100.00
71 INT38268 Positive_regulation of BEST1 16 0.17 14.54 1.93 100.00
72 INT92941 Binding of ASAP1 24 0.39 12.38 1.25 100.00
73 INT100051 Binding of MUC5AC 20 0.32 14.21 1.14 100.00
74 INT335450 Positive_regulation of Localization of INTU 1 0.16 0.82 0.24 100.00
75 INT67333 Negative_regulation of ITGB2 10 0.41 6.92 3.06 100.00
76 INT170900 Regulation of Positive_regulation of Gopc 10 0.20 3.44 1.24 100.00
77 INT336921 Positive_regulation of Localization of Mir341 1 0.03 1.24 0.14 100.00
78 INT336915 Localization of Mir341 1 0.06 1.24 0.14 100.00
79 INT336919 Negative_regulation of Localization of Mir341 1 0.03 1.24 0.14 100.00
80 INT100086 Negative_regulation of Localization of Tlr4 15 0.37 5.92 2.47 100.00
81 INT158397 Binding of ARID1A 4 0.29 1.11 0.38 100.00
82 INT275603 Regulation of Negative_regulation of COPD 1 0.03 0.88 0 100.00
83 INT546 Binding of ALB 311 0.48 85.98 60.14 100.00
84 INT133269 Positive_regulation of PDX1 10 0.54 9.77 1.9 100.00
85 INT59790 Binding of BCR 16 0.36 15.34 1.75 100.00
86 INT103020 Gene_expression of SGCA 22 0.56 14.29 2.75 100.00
87 INT325353 Regulation of Binding of COPD 1 0.25 0.56 0.13 100.00
88 INT145281 Gene_expression of hb 89 0.59 63.22 11.96 99.98
89 INT19483 Positive_regulation of Ppcs 3 0.37 14.1 1.36 99.98
90 INT35349 Gene_expression of CENPJ 52 0.57 25.36 2.54 99.98
91 INT90766 Gene_expression of PCS 93 0.77 40.48 14.51 99.98
92 INT63534 Binding of CRH 23 0.47 6.84 3.43 99.98
93 INT132994 Positive_regulation of Localization of Mmp9 12 0.42 9.4 3.75 99.98
94 INT193210 Gene_expression of TCF23 2 0.46 0.44 0 99.98
95 INT22781 Binding of COL7A1 76 0.48 41.59 6.66 99.98
96 INT7995 Positive_regulation of Lta 28 0.66 14.98 9.8 99.98
97 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 99.96
98 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 99.96
99 INT1199 Positive_regulation of INS 579 0.70 399.64 50.43 99.96
100 INT131351 Positive_regulation of Gene_expression of Nppb 2 0.50 13.72 1.14 99.96
101 INT193042 Positive_regulation of Gene_expression of Chrm2 15 0.28 3.93 0.86 99.96
102 INT193067 Positive_regulation of Transcription of CHRM2 1 0.03 1.03 0.13 99.96
103 INT11159 Gene_expression of EGFR 698 0.78 548.93 25.69 99.92
104 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210 99.92
105 INT184384 Gene_expression of DNAI1 8 0.66 5.45 1.05 99.92
106 INT92877 Gene_expression of PDE5A 35 0.76 17.1 2.7 99.92
107 INT17511 Negative_regulation of PRTN3 19 0.41 12 3.3 99.92
108 INT96622 Localization of Trpv1 110 0.81 59.82 63.25 99.92
109 INT12339 Localization of IL8 437 0.81 251.87 117.39 99.90
110 INT54358 Localization of Ltb4r1 13 0.34 14.31 2.6 99.90
111 INT25396 Localization of Ptger2 83 0.78 46.81 14.81 99.90
112 INT10049 Negative_regulation of SERPINA1 56 0.59 44.52 9.93 99.90
113 INT11807 Gene_expression of Il2 266 0.78 112 64.97 99.90
114 INT173693 Localization of Gopc 249 0.65 70.49 38.81 99.90
115 INT11803 Positive_regulation of Il2 62 0.70 31.44 18.93 99.90
116 INT4391 Gene_expression of SERPINA1 47 0.78 41.43 9.7 99.90
117 INT183065 Positive_regulation of Gene_expression of PDX1 7 0.54 6.58 1.29 99.90
118 INT257353 Gene_expression of Defb19 2 0.09 0.73 0 99.90
119 INT49850 Negative_regulation of PDE4A 105 0.58 76.91 26.59 99.88
120 INT30169 Negative_regulation of Pde4a 107 0.58 81 36.23 99.88
121 INT190204 Positive_regulation of Gene_expression of MMP12 22 0.67 31.31 13.69 99.88
122 INT76339 Positive_regulation of Ltb4r1 23 0.45 22.78 3.58 99.88
123 INT8662 Positive_regulation of EDN1 144 0.70 125.34 19.59 99.88
124 INT4985 Positive_regulation of Tac1 81 0.69 35.79 50.67 99.88
125 INT336920 Negative_regulation of Mir341 1 0.03 3.02 0.55 99.88
126 INT5650 Gene_expression of Mpo 117 0.77 80.27 26.42 99.88
127 INT117476 Negative_regulation of Gene_expression of Mpo 10 0.43 8.25 3.33 99.88
128 INT28325 Negative_regulation of Tst 13 0.51 12.41 3.16 99.88
129 INT100498 Negative_regulation of Positive_regulation of Tac1 3 0.41 2.81 2.06 99.88
130 INT4465 Gene_expression of CEL 116 0.77 98.35 23.58 99.84
131 INT133028 Gene_expression of TLR2 209 0.73 131.92 36.17 99.84
132 INT51983 Negative_regulation of Prtn3 23 0.34 12.54 5 99.84
133 INT79456 Gene_expression of PDE4A 35 0.77 19.42 7.42 99.84
134 INT10833 Regulation of Gene_expression of IL8 68 0.62 38.74 18.46 99.84
135 INT113101 Gene_expression of Ccl11 41 0.76 22.36 5.47 99.84
136 INT10837 Positive_regulation of Gene_expression of IL8 294 0.70 190.08 70.34 99.84
137 INT1950 Positive_regulation of Positive_regulation of Tlr4 38 0.49 20.17 7.14 99.84
138 INT23245 Positive_regulation of Gene_expression of CEL 19 0.69 14.81 4.92 99.84
139 INT186738 Positive_regulation of Gene_expression of Ccl11 14 0.67 8.55 1.45 99.84
140 INT72182 Gene_expression of Mcpt1 167 0.75 123.7 52.15 99.84
141 INT127668 Positive_regulation of PDE4A 12 0.68 8.39 5.13 99.84
142 INT10874 Negative_regulation of Twist1 89 0.50 36.84 11.32 99.84
143 INT9083 Gene_expression of Nppb 74 0.78 70.96 12.19 99.84
144 INT259631 Negative_regulation of PDE4B 4 0.10 4.88 1.54 99.84
145 INT179654 Positive_regulation of Eln 5 0.44 4.3 0.43 99.84
146 INT6596 Positive_regulation of HLA-DRB1 33 0.61 27.01 7.26 99.84
147 INT274178 Binding of BBS2 1 0.27 2.12 0.82 99.84
148 INT14557 Negative_regulation of Igf1 96 0.59 54.83 4.45 99.84
149 INT121475 Regulation of Negative_regulation of Twist1 3 0.14 2.43 0.24 99.84
150 INT179362 Gene_expression of Smcp 5 0.54 4.5 0.52 99.84
151 INT259662 Positive_regulation of Regulation of HDAC4 1 0.03 0.77 0.03 99.84
152 INT124568 Regulation of HDAC4 5 0.24 3.03 0.27 99.84
153 INT141502 Positive_regulation of CX3CL1 21 0.55 25.8 8.88 99.84
154 INT22535 Negative_regulation of Glrx 3 0.22 1.31 1.11 99.84
155 INT35536 Negative_regulation of CAT 26 0.57 14.39 5.38 99.84
156 INT78816 Positive_regulation of Positive_regulation of ICAM1 9 0.68 8.36 1.55 99.84
157 INT259607 Positive_regulation of Negative_regulation of Prtn3 1 0.29 0.63 0.12 99.84
158 INT336832 Gene_expression of CACNG6 1 0.78 2.88 1.01 99.84
159 INT148402 Gene_expression of Chrm2 95 0.54 24.25 5.27 99.82
160 INT46722 Regulation of Gene_expression of Csf2 8 0.45 4.84 1.45 99.82
161 INT11048 Gene_expression of CD69 59 0.67 42.85 6.4 99.80
162 INT47075 Positive_regulation of Ptger2 142 0.70 78.55 25.47 99.80
163 INT194611 Gene_expression of Klrk1 28 0.44 19.31 1.28 99.80
164 INT17881 Gene_expression of LEP 278 0.78 221.61 48.31 99.80
165 INT6852 Localization of TNF 883 0.81 705.95 270.84 99.80
166 INT11052 Positive_regulation of Gene_expression of CD69 23 0.43 16.66 2.54 99.80
167 INT66606 Gene_expression of CXCR1 34 0.75 27.79 11.36 99.80
168 INT19929 Negative_regulation of Positive_regulation of TNF 52 0.59 38.16 16.51 99.80
169 INT79395 Gene_expression of Twist1 193 0.77 100.06 26.34 99.80
170 INT259667 Negative_regulation of Hdac2 1 0.13 0.92 0.03 99.80
171 INT172996 Gene_expression of MUC2 14 0.69 11.01 0.42 99.80
172 INT86705 Gene_expression of BTG3 41 0.65 37.29 8.29 99.80
173 INT170854 Gene_expression of CFD 26 0.68 39.77 4.74 99.80
174 INT199798 Positive_regulation of BBS2 2 0.50 5.85 2.55 99.78
175 INT22708 Gene_expression of MUC1 297 0.78 232.71 24.19 99.76
176 INT145279 Regulation of hb 19 0.34 16.58 2.41 99.76
177 INT47949 Positive_regulation of ELOVL1 19 0.42 29.78 3.3 99.76
178 INT172131 Positive_regulation of Gene_expression of fc 20 0.14 14.23 3.84 99.76
179 INT4369 Gene_expression of Ldha 157 0.76 88.12 22.45 99.76
180 INT69239 Negative_regulation of Gene_expression of pcp 2 0.03 0.36 0.2 99.76
181 INT613 Gene_expression of Alb 268 0.78 149.84 42.78 99.74
182 INT272883 Positive_regulation of Gene_expression of Hdac2 5 0.30 4.64 0.7 99.74
183 INT262797 Regulation of Gene_expression of Smad3 2 0.34 2.27 0.25 99.74
184 INT140794 Gene_expression of Smad3 22 0.64 9.41 0.83 99.74
185 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 99.72
186 INT15516 Gene_expression of Crp 711 0.77 615.33 173.09 99.72
187 INT89309 Negative_regulation of Pde4b 21 0.53 12.81 7.32 99.72
188 INT50970 Positive_regulation of Ntrk1 51 0.57 29.38 22.83 99.72
189 INT192225 Gene_expression of HDAC9 35 0.58 32.82 6.36 99.72
190 INT60694 Gene_expression of Il10 567 0.78 369.48 143.69 99.72
191 INT213887 Gene_expression of MICB 10 0.19 15.33 0.39 99.70
192 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 99.70
193 INT57959 Positive_regulation of Prf1 12 0.41 5.29 1.47 99.70
194 INT242445 Positive_regulation of Gene_expression of Prf1 4 0.40 1.31 0.41 99.70
195 INT129612 Positive_regulation of Gene_expression of Id2 4 0.67 3.61 0.22 99.70
196 INT9110 Binding of PAH 32 0.41 42.1 3.1 99.70
197 INT20492 Gene_expression of MMP12 89 0.76 81.36 46.12 99.68
198 INT9951 Gene_expression of ANGPTL5 45 0.53 37.2 6.44 99.68
199 INT69160 Positive_regulation of IL5 41 0.65 36.04 7.75 99.68
200 INT272055 Negative_regulation of NEU3 8 0.06 9.73 0.27 99.68
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