D:Pycnodysostosis

From wiki-pain
Jump to: navigation, search

pChart

Disease Term
Synonyms PYCNODYSOSTOSES, Pyknodysostoses, Pyknodysostosis
Documents 8
Hot Single Events 12
Hot Interactions 2

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Pycnodysostosis. They are ordered first by their relevance to Pycnodysostosis and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT97188 Gh Positive_regulation of Localization of Igf1 1 0.02 0.54 0.25 97.72
2 INT181998 TNFRSF11B Negative_regulation of Gene_expression of CTSK 1 0.07 1.98 0.27 86.20
3 INT264148 Binding of CLCN7 and Ostm1 1 0.17 0.72 0.03 22.24
4 INT264144 CLCN7 Regulation of ADO 1 0.04 0.71 0 16.48
5 INT181996 TNFRSF11B Positive_regulation of Gene_expression of TIMP1 1 0.00 0.67 0.18 5.00
6 INT181997 TNFRSF11B Negative_regulation of CTSK 1 0.05 0.58 0.14 5.00
7 INT264143 TCIRG1 Regulation of BSND 1 0.02 0.74 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Pycnodysostosis. They are ordered first by their pain relevance and then by number of times they were reported in Pycnodysostosis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT146660 Negative_regulation of Ctsk 9 0.43 6.01 2.07 99.74
2 INT1497 Negative_regulation of Gh 415 0.59 192.95 74.71 99.72
3 INT49362 Positive_regulation of Localization of Igf1 4 0.65 2.26 0.53 96.92
4 INT49360 Localization of Igf1 22 0.76 6.96 4.26 96.52
5 INT17539 Positive_regulation of Igf1 68 0.69 28.47 13.02 93.08
6 INT173578 Negative_regulation of CTSK 8 0.44 6.29 1.15 91.56
7 INT1498 Gene_expression of Gh 521 0.75 220.84 81.16 89.92
8 INT1894 Negative_regulation of Localization of Gh 168 0.58 64.12 43.56 87.24
9 INT1893 Localization of Gh 1041 0.79 340.23 256.58 86.84
10 INT91527 Gene_expression of CTSK 38 0.78 22.21 7.42 84.36
11 INT97152 Protein_catabolism of COL1A1 11 0.74 8.03 2.3 82.88
12 INT179788 Gene_expression of Sparc 42 0.77 19.96 2.57 81.20
13 INT11659 Gene_expression of COL2A1 164 0.78 78.49 22.58 79.92
14 INT19963 Gene_expression of COL1A1 118 0.59 42.11 15.15 78.48
15 INT71047 Gene_expression of CYP19A1 122 0.78 68.78 22.21 59.28
16 INT23533 Gene_expression of CA2 110 0.75 30.81 19.4 58.72
17 INT108306 Positive_regulation of TNFRSF11B 28 0.60 12.74 4.46 47.84
18 INT17612 Gene_expression of CRP 676 0.78 580.61 119.03 10.28
19 INT1759 Gene_expression of TIMP1 267 0.77 133.87 59.29 5.00
20 INT100861 Binding of CRP 179 0.48 175.2 26.45 5.00
21 INT23257 Regulation of CRP 127 0.62 100.05 21.87 5.00
22 INT46619 Gene_expression of CSF1 80 0.73 36.63 12.94 5.00
23 INT17283 Positive_regulation of CSF1 37 0.59 24.16 10.01 5.00
24 INT19965 Positive_regulation of COL1A1 23 0.45 14.49 4.38 5.00
25 INT158978 Localization of TNFRSF11B 19 0.78 11.8 3.32 5.00
26 INT130865 Positive_regulation of TNFSF11 29 0.69 12.82 2.99 5.00
27 INT49250 Regulation of Atp6v0d2 5 0.08 1.54 2.04 5.00
28 INT216848 Gene_expression of TCIRG1 8 0.52 2.59 1.95 5.00
29 INT153775 Positive_regulation of CTSK 9 0.52 5.44 1.9 5.00
30 INT182005 Positive_regulation of Gene_expression of CTSK 7 0.52 4.01 1.08 5.00
31 INT153773 Regulation of Gene_expression of CTSK 2 0.34 1.36 0.62 5.00
32 INT259408 Gene_expression of Atp6v0d2 5 0.09 2.01 0.54 5.00
33 INT133316 Localization of CTSK 5 0.52 2.43 0.43 5.00
34 INT90090 Gene_expression of ADO 4 0.58 1.41 0.42 5.00
35 INT182004 Regulation of Localization of CTSK 1 0.20 0.58 0.18 5.00
36 INT264145 Gene_expression of BSND 1 0.04 1.25 0 5.00
37 INT264146 Gene_expression of MYO7A 1 0.05 1.36 0 5.00
38 INT264147 Gene_expression of CLCN7 1 0.35 0.73 0 5.00
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox