D:Quadriplegia

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Disease Term
Synonyms FLACCID QUADRIPLEGIA, Flaccid Quadriplegias, Flaccid Tetraplegia, Flaccid Tetraplegias, Locked In Syndrome, Locked In Syndromes, Paralysis Spinal Quadriplegic, QUADRIPARESES, Quadriparesis, Quadriplegia Flaccid, QUADRIPLEGIA SPASTIC
Documents 533
Hot Single Events 37
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Quadriplegia. They are ordered first by their relevance to Quadriplegia and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT65185 Binding of ATRX and Ssr1 1 0.03 1.68 0.49 75.00
2 INT65184 Binding of CSCI and Ssr1 1 0.04 1.67 0.48 75.00
3 INT196592 Binding of CFD and GHRH 1 0.02 1.88 0.07 24.48
4 INT320701 Binding of SMARCC1 and C1QL3 1 0.00 0.71 0 12.48
5 INT355018 Binding of FAS and Faslg 1 0.12 1.34 0.37 5.00
6 INT262307 CAPNS1 Regulation of TAF9 1 0.04 1.23 0.33 5.00
7 INT259023 CADPS Positive_regulation of Binding of SH2B2 1 0.06 2.05 0.14 5.00
8 INT355023 Phosphorylation of Rtn4r Negative_regulation of Binding of Mag and Rtn4r 1 0.00 0.38 0.11 5.00
9 INT355008 Binding of Mag and Rtn4r 1 0.02 0.36 0.1 5.00
10 INT226044 Lta Positive_regulation of Ecm1 1 0.02 0.44 0.08 5.00
11 INT355019 Lif Positive_regulation of JAK1 1 0.00 0.69 0.08 5.00
12 INT355021 Cntf Positive_regulation of SOAT1 1 0.02 0.7 0.08 5.00
13 INT355022 Cntf Positive_regulation of JAK1 1 0.00 0.69 0.08 5.00
14 INT355009 Cntf Positive_regulation of Il6st 1 0.02 0.69 0.08 5.00
15 INT355020 Lif Positive_regulation of SOAT1 1 0.02 0.7 0.08 5.00
16 INT355010 Lif Positive_regulation of Il6st 1 0.02 0.69 0.08 5.00
17 INT226043 Epo Positive_regulation of Ecm1 1 0.04 1.35 0.05 5.00
18 INT340648 Binding of Mkrn1 and Tg(CAG-EGFP)D4Nagy 1 0.12 0.57 0.03 5.00
19 INT340647 Regulation of Binding of Mkrn1 and Tg(CAG-EGFP)D4Nagy 1 0.09 0.38 0.03 5.00
20 INT226045 Binding of Casp1 and Lta 1 0.04 0.73 0 5.00
21 INT226042 Binding of Casp1 and Casp3 1 0.02 0.73 0 5.00
22 INT345060 Binding of SGCG and C2 1 0.00 0.93 0 5.00
23 INT320702 Binding of PMVK and C1QL3 1 0.01 0.06 0 5.00
24 INT345059 Binding of C3 and C2 1 0.00 0 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Quadriplegia. They are ordered first by their pain relevance and then by number of times they were reported in Quadriplegia. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT90291 Gene_expression of LMNB1 6 0.38 7.75 0.86 100.00
2 INT28929 Negative_regulation of PVR 22 0.57 16.64 1.07 100.00
3 INT39819 Localization of C4A 4 0.62 3.1 0.72 99.40
4 INT1166 Negative_regulation of Dbh 56 0.59 12.54 28.26 99.22
5 INT12265 Positive_regulation of IgG 168 0.63 104.89 19.76 98.96
6 INT55309 Positive_regulation of Ssr1 20 0.46 5.97 5.74 97.74
7 INT55310 Gene_expression of Ssr1 20 0.67 3.47 2.56 97.74
8 INT5361 Positive_regulation of CPM 4 0.60 1.61 0.09 97.56
9 INT8959 Binding of Gnb5 17 0.40 31.38 5.1 97.44
10 INT41789 Negative_regulation of Moxd2 6 0.57 4.03 2.49 97.44
11 INT58192 Positive_regulation of MRI1 86 0.61 53.81 24.68 96.72
12 INT2152 Transcription of Cpm 2 0.66 1.3 0.5 96.32
13 INT156427 Localization of FOXC1 2 0.73 1.36 1.07 94.52
14 INT125980 Binding of CFD 8 0.42 10.96 1.39 93.84
15 INT2280 Negative_regulation of TNFAIP1 70 0.43 69.43 8.36 93.56
16 INT3758 Gene_expression of ALB 326 0.78 184.65 38.75 91.76
17 INT3952 Negative_regulation of ALB 116 0.59 72.18 18.35 91.76
18 INT2393 Positive_regulation of Mb 174 0.69 93.59 26.79 91.28
19 INT505 Positive_regulation of GPT 89 0.67 69.38 14.94 91.28
20 INT1934 Positive_regulation of Cys1 68 0.68 60.56 10.47 91.28
21 INT2072 Localization of AMBP 33 0.65 37.58 4.84 91.24
22 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74 90.12
23 INT19396 Regulation of Rac1 66 0.53 37.41 30.01 89.88
24 INT46827 Negative_regulation of ADAMTS1 2 0.42 0.93 0.26 89.12
25 INT62689 Negative_regulation of PPOX 7 0.58 4.66 0.28 88.36
26 INT61316 Gene_expression of Coq10a 59 0.73 32.81 3.95 87.32
27 INT58208 Negative_regulation of Ctsl 8 0.53 3.49 1.91 87.12
28 INT100375 Gene_expression of Vhl 14 0.15 22.3 1.69 86.32
29 INT100376 Positive_regulation of Gene_expression of Vhl 4 0.10 6.47 1.47 86.32
30 INT48246 Gene_expression of PLP1 18 0.64 10.33 4.73 86.00
31 INT48308 Binding of PLP1 7 0.48 9.59 6.09 85.36
32 INT27534 Negative_regulation of Gba 10 0.57 6.23 0.38 85.16
33 INT85640 Gene_expression of Tg(CAG-EGFP)D4Nagy 1138 0.72 311.58 119.18 83.52
34 INT102545 Gene_expression of Ccr2 42 0.78 61.43 19.81 83.52
35 INT168642 Gene_expression of Cx3cr1 15 0.77 21.73 8.1 83.52
36 INT199692 Gene_expression of Mkrn1 48 0.75 15.2 3.84 83.52
37 INT48406 Gene_expression of Icam1 277 0.78 238.28 81.71 83.00
38 INT102187 Gene_expression of SH2B2 23 0.59 26.54 4.39 79.52
39 INT62690 Gene_expression of PPOX 7 0.77 3.3 0.13 79.44
40 INT11051 Positive_regulation of Gene_expression of IL6 415 0.69 319.21 109.3 78.44
41 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 78.44
42 INT9234 Negative_regulation of Gene_expression of IL6 171 0.59 101.61 53.15 78.44
43 INT60526 Gene_expression of IL10 449 0.78 292.71 107.84 78.44
44 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 78.04
45 INT48901 Negative_regulation of IL6 186 0.57 136.33 57.87 78.04
46 INT256411 Phosphorylation of AMBP 1 0.08 10.3 0.73 77.96
47 INT73502 Positive_regulation of IL10 154 0.69 124.87 43.5 77.32
48 INT70050 Negative_regulation of IL10 56 0.58 37.45 12.39 77.32
49 INT25 Positive_regulation of LAMC2 19 0.67 8.64 7.06 76.52
50 INT204019 Negative_regulation of C2 10 0.26 6.23 2.44 76.36
51 INT2805 Negative_regulation of C7 1 0.26 0.73 0.11 75.32
52 INT196595 Regulation of Localization of CFD 1 0.39 2.03 0.04 75.20
53 INT1704 Positive_regulation of PCa 68 0.59 34.92 23.36 75.00
54 INT10917 Positive_regulation of ITGAM 31 0.67 16.39 6.69 74.40
55 INT196594 Localization of CFD 4 0.65 4.36 0.39 74.40
56 INT4420 Positive_regulation of GOT1 103 0.64 88.4 18.38 71.28
57 INT54848 Protein_catabolism of SGCG 12 0.96 3.8 3.78 70.88
58 INT45352 Negative_regulation of THTPA 2 0.37 1.45 0.45 70.32
59 INT49750 Negative_regulation of CPOX 735 0.58 360.06 274.19 69.88
60 INT128946 Regulation of PNPLA6 1 0.27 2.14 0.36 68.88
61 INT82719 Positive_regulation of ASF1A 2 0.08 9.55 3 67.84
62 INT262317 Binding of TAF9 7 0.31 9.67 2.15 67.56
63 INT144112 Regulation of Binding of CPM 1 0.26 0.75 0.22 64.64
64 INT117796 Binding of CPM 5 0.48 2.79 0.45 64.00
65 INT144113 Binding of STX2 1 0.47 0.75 0.21 64.00
66 INT92678 Positive_regulation of Ecm1 30 0.09 28.41 3.68 62.56
67 INT170854 Gene_expression of CFD 26 0.68 39.77 4.74 60.08
68 INT81929 Negative_regulation of Gene_expression of IL10 41 0.57 27.99 9.87 58.72
69 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 57.52
70 INT2512 Negative_regulation of Cp 27 0.51 10.15 8.37 57.20
71 INT4960 Positive_regulation of CSF2 285 0.70 256.73 65.73 57.12
72 INT70048 Positive_regulation of Gene_expression of IL10 90 0.55 71.34 25.66 57.12
73 INT22301 Positive_regulation of Gene_expression of CSF2 66 0.63 59.49 14.24 57.12
74 INT11587 Gene_expression of CSF2 645 0.78 544.38 93.89 55.20
75 INT2542 Localization of Calca 2008 0.81 518.3 1408.65 54.00
76 INT35584 Binding of ACLY 22 0.35 31.78 7.17 53.20
77 INT34864 Binding of Cp 23 0.47 5.17 1.78 51.36
78 INT1125 Positive_regulation of IGHG3 130 0.69 112.07 13.18 50.76
79 INT8021 Gene_expression of Enpp1 43 0.78 31.46 10.8 49.32
80 INT172851 Gene_expression of YES1 4 0.59 0.96 0.41 48.88
81 INT14501 Gene_expression of CST3 28 0.75 25.77 5.16 45.68
82 INT14500 Positive_regulation of Gene_expression of CST3 9 0.67 7.46 1.87 45.68
83 INT186181 Gene_expression of ZC3H12A 4 0.08 2.91 0.85 41.12
84 INT82918 Binding of AMBP 23 0.39 23.31 1.71 37.36
85 INT11554 Negative_regulation of CSF2 129 0.59 108.55 29.44 37.00
86 INT203558 Binding of TEDDM1 1 0.02 0.05 0.46 36.56
87 INT9408 Positive_regulation of Crp 296 0.69 242.27 57.35 35.72
88 INT56374 Gene_expression of AMBP 34 0.54 35.85 6.25 33.60
89 INT86999 Regulation of DYNLL1 5 0.44 2.85 2.18 33.28
90 INT937 Positive_regulation of Oxt 195 0.70 37.82 49.3 29.80
91 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 29.08
92 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210 29.08
93 INT11313 Positive_regulation of Il6 526 0.70 331.27 201.59 29.08
94 INT49993 Positive_regulation of Gene_expression of Il6 149 0.70 88.07 53.78 29.08
95 INT16868 Gene_expression of Il6 807 0.78 499.48 256.57 28.72
96 INT259865 Gene_expression of Aibl 2 0.07 2.32 0.2 26.96
97 INT256412 Negative_regulation of Localization of AMBP 1 0.04 6.09 1.14 26.32
98 INT188760 Regulation of ZC3H12A 4 0.04 4.02 0.27 24.56
99 INT320703 Binding of SMARCC1 1 0.03 0.77 0 20.16
100 INT320706 Positive_regulation of SMARCC1 1 0.06 0.97 0 19.84
101 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98 15.36
102 INT196593 Phosphorylation of CFD 1 0.55 0.84 0.04 6.92
103 INT174664 Binding of ZC3H12A 1 0.07 0.92 0 5.84
104 INT22764 Localization of Ptger2 81 0.64 24.38 26.77 5.52
105 INT3034 Localization of Ngf 126 0.81 50.81 72.84 5.04
106 INT1912 Gene_expression of Calca 1152 0.78 453.25 739.84 5.00
107 INT5680 Gene_expression of Ngf 530 0.78 264.29 310.56 5.00
108 INT6852 Localization of TNF 883 0.81 705.95 270.84 5.00
109 INT1562 Localization of Crh 499 0.81 126.74 236.68 5.00
110 INT867 Gene_expression of IFNA1 930 0.78 594.85 168.03 5.00
111 INT6042 Binding of Oprm1 248 0.48 31.77 154.34 5.00
112 INT120811 Gene_expression of Gopc 1174 0.59 428.49 150.55 5.00
113 INT15515 Positive_regulation of Crp 700 0.70 604.24 150.15 5.00
114 INT9660 Regulation of TNF 363 0.62 312.94 139.99 5.00
115 INT65600 Positive_regulation of Casp3 376 0.70 198.44 128.03 5.00
116 INT5842 Gene_expression of Gfap 372 0.78 153.71 127.71 5.00
117 INT4824 Positive_regulation of Tacr1 169 0.70 66.1 123.46 5.00
118 INT9235 Negative_regulation of Gene_expression of TNF 346 0.59 252.98 118.61 5.00
119 INT1438 Localization of Pomc 360 0.81 101.26 116.47 5.00
120 INT4936 Localization of Tacr1 125 0.80 35.7 107.7 5.00
121 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 5.00
122 INT82448 Gene_expression of S100a8 246 0.77 236.72 84.02 5.00
123 INT75999 Gene_expression of BDNF 344 0.78 114.19 83.12 5.00
124 INT16254 Positive_regulation of Gene_expression of Ngf 144 0.70 80.61 82.08 5.00
125 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65 5.00
126 INT2893 Localization of Oxt 219 0.80 28.96 79.43 5.00
127 INT12001 Regulation of Ngf 97 0.62 54.64 76.25 5.00
128 INT10359 Gene_expression of Ifng 159 0.78 79.6 72.14 5.00
129 INT5058 Positive_regulation of IFNA1 356 0.70 245.75 60.52 5.00
130 INT31116 Gene_expression of Casp3 192 0.78 78.21 57.43 5.00
131 INT4509 Gene_expression of IgG 426 0.76 293.69 56.64 5.00
132 INT647 Gene_expression of SGCG 211 0.75 78.46 55.82 5.00
133 INT251 Regulation of INS 398 0.62 232.47 55.04 5.00
134 INT22112 Positive_regulation of Localization of TNF 164 0.70 115.66 52.18 5.00
135 INT8690 Localization of Tac1 71 0.80 22.98 50.75 5.00
136 INT4345 Gene_expression of Gtf3a 157 0.67 80.75 48.47 5.00
137 INT42980 Gene_expression of GAD1 139 0.69 94.77 45.11 5.00
138 INT2774 Binding of Crp 241 0.48 195.89 44.39 5.00
139 INT19078 Binding of Ngf 78 0.48 31.03 44.33 5.00
140 INT4216 Gene_expression of CD40LG 328 0.78 256.02 44.23 5.00
141 INT613 Gene_expression of Alb 268 0.78 149.84 42.78 5.00
142 INT11439 Positive_regulation of Csf2 105 0.69 62.63 37.77 5.00
143 INT101992 Localization of VEGFA 413 0.81 258.23 36.15 5.00
144 INT927 Gene_expression of Oxt 184 0.78 44.71 35.79 5.00
145 INT1705 Gene_expression of pCA 126 0.65 88.65 34.81 5.00
146 INT53475 Gene_expression of MRI1 116 0.59 77.68 33.98 5.00
147 INT11325 Gene_expression of HLA-E 209 0.76 98.05 33.72 5.00
148 INT6302 Binding of IFNA1 196 0.48 133.85 32.73 5.00
149 INT22939 Gene_expression of Csf2 164 0.78 85.1 32.22 5.00
150 INT29503 Gene_expression of Mmp2 95 0.77 56.92 31.68 5.00
151 INT719 Negative_regulation of SGCG 96 0.57 47.91 30.22 5.00
152 INT15610 Localization of GOPC 223 0.65 68.26 28.7 5.00
153 INT66200 Gene_expression of Gfap 215 0.78 88.04 28.25 5.00
154 INT78251 Positive_regulation of LBP 38 0.69 39.98 26.73 5.00
155 INT5966 Localization of Il1a 50 0.78 22.91 26.54 5.00
156 INT9682 Positive_regulation of IGF1 238 0.70 120.03 26.36 5.00
157 INT56224 Negative_regulation of Gene_expression of Ifng 40 0.58 23.34 25.08 5.00
158 INT55583 Localization of IFNA1 135 0.78 85.07 24.13 5.00
159 INT11746 Positive_regulation of Il1a 65 0.63 42.94 23.54 5.00
160 INT74423 Localization of IL10 91 0.80 61.6 22.95 5.00
161 INT49196 Gene_expression of SELE 105 0.78 107.29 22.92 5.00
162 INT6270 Binding of HTR1D 55 0.47 9.54 22.86 5.00
163 INT6868 Gene_expression of GFAP 136 0.78 84.65 22.7 5.00
164 INT74682 Positive_regulation of Mmp2 72 0.69 40.46 21.73 5.00
165 INT14700 Regulation of IFNA1 111 0.45 66.16 21.52 5.00
166 INT137767 Gene_expression of Eae1 74 0.34 89.32 20.48 5.00
167 INT111401 Positive_regulation of Gene_expression of Tg(CAG-EGFP)D4Nagy 134 0.61 34.87 20.15 5.00
168 INT48663 Negative_regulation of Gene_expression of Gfap 45 0.59 18.34 19.84 5.00
169 INT9782 Binding of HTR1B 43 0.47 12.08 19.83 5.00
170 INT58477 Gene_expression of Chdh 33 0.74 39.48 19.78 5.00
171 INT7581 Binding of ADHD1 132 0.46 135.1 19.73 5.00
172 INT78694 Positive_regulation of Gene_expression of Casp3 46 0.66 18.64 19.62 5.00
173 INT7994 Gene_expression of Lta 113 0.67 69.81 19.59 5.00
174 INT5398 Positive_regulation of ALPP 178 0.70 110.52 19.18 5.00
175 INT78024 Gene_expression of ACLY 73 0.75 59.15 18.54 5.00
176 INT20260 Positive_regulation of Chkb 41 0.64 21.48 18.53 5.00
177 INT18010 Positive_regulation of CD40LG 122 0.70 100.8 18.46 5.00
178 INT103469 Positive_regulation of Gene_expression of BDNF 59 0.67 24.39 18.36 5.00
179 INT20631 Positive_regulation of CHKB 166 0.69 109.86 17.92 5.00
180 INT24225 Gene_expression of Alms1 93 0.62 52.75 16.93 5.00
181 INT5841 Gene_expression of Vim 181 0.72 138.54 16.33 5.00
182 INT11685 Regulation of CSF2 99 0.59 58.82 15.9 5.00
183 INT85639 Positive_regulation of Tg(CAG-EGFP)D4Nagy 95 0.43 24.83 15.69 5.00
184 INT70265 Regulation of MRI1 42 0.39 30.95 14.18 5.00
185 INT5207 Negative_regulation of Alms1 70 0.41 41.56 13.68 5.00
186 INT20264 Gene_expression of Chkb 29 0.46 13.14 13.65 5.00
187 INT11699 Binding of HLA-E 85 0.47 52.51 13.41 5.00
188 INT100655 Regulation of BDNF 51 0.60 21.49 13.14 5.00
189 INT81629 Positive_regulation of Fas 58 0.70 59.63 12.94 5.00
190 INT49041 Transcription of Tacr1 25 0.72 12.52 12.8 5.00
191 INT41728 Gene_expression of CHAT 65 0.75 42.19 12.73 5.00
192 INT49975 Binding of SLC6A3 34 0.47 9.86 12.41 5.00
193 INT50580 Binding of PPIG 39 0.36 11.17 12.34 5.00
194 INT184853 Gene_expression of ADHD1 87 0.65 89.2 11.8 5.00
195 INT50933 Transcription of Il6 38 0.72 24.31 11.58 5.00
196 INT38255 Localization of Chkb 32 0.80 10.98 11.07 5.00
197 INT158070 Localization of Aes 23 0.65 19.93 10.9 5.00
198 INT74681 Positive_regulation of Gene_expression of Mmp2 23 0.55 15.58 10.74 5.00
199 INT72579 Localization of BDNF 56 0.80 14.84 10.65 5.00
200 INT135022 Gene_expression of Cd14 79 0.76 36.37 10.63 5.00
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