D:Rare Diseases

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Disease Term
Synonyms Disease Orphan, Disease Rare, Diseases Orphan, DISEASES RARE, Orphan Disease, Orphan Diseases, Rare Disease
Documents 1202
Hot Single Events 95
Hot Interactions 2

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Rare Diseases. They are ordered first by their relevance to Rare Diseases and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT331628 Binding of HLA-DQA2 and Pain1 1 0.01 2.13 0.14 87.16
2 INT331627 Binding of HLA-DRB3 and Pain1 1 0.00 2.15 0.14 87.16
3 INT291041 IL6 Regulation of IL36RN 1 0.00 1.09 0.17 69.12
4 INT239080 Binding of PPY and KAT2B 1 0.02 2.38 0 65.84
5 INT150393 Binding of CASP1 and MEFV 2 0.16 2.48 0.45 59.56
6 INT334879 CASP1 Regulation of IL1B 1 0.03 1.63 0.31 58.36
7 INT317833 Nlrp3 Positive_regulation of Localization of Il1 1 0.06 1.38 0.26 56.52
8 INT231521 Binding of IARS and POMT1 1 0.03 0.72 0 36.40
9 INT289294 Binding of CD59 and Atp6ap1 1 0.10 0.51 0 32.00
10 INT289298 Negative_regulation of Binding of CD59 and Atp6ap1 1 0.12 0.51 0 32.00
11 INT289296 Binding of CD59 and C6 1 0.02 0.5 0 31.68
12 INT289297 Negative_regulation of Binding of CD59 and C6 1 0.02 0.51 0 31.68
13 INT206764 Binding of AQP4 and Nqo1 8 0.05 13.45 2.84 25.00
14 INT97188 Gh Positive_regulation of Localization of Igf1 1 0.02 0.54 0.25 25.00
15 INT246640 GAST Positive_regulation of NFASC 1 0.00 1.26 0.03 18.72
16 INT317832 Binding of Mefv and Il1 1 0.03 3.89 0.7 6.32
17 INT317834 Binding of Pstpip1 and Il1 1 0.00 2.03 0.48 6.32
18 INT197051 Binding of HLA-E and ATP8A1 1 0.00 6.52 1.14 5.00
19 INT317836 Binding of Fibp and Pycard 1 0.00 2.68 0.98 5.00
20 INT166983 Binding of HLA-B and HSPG2 4 0.08 4.66 0.88 5.00
21 INT332699 Binding of KNG1 and TRGC1 1 0.16 3.37 0.75 5.00
22 INT267625 Binding of KNG1 and Klk1 2 0.21 2.23 0.61 5.00
23 INT197050 Binding of HLA-DOA and HLA-E 2 0.08 1.73 0.58 5.00
24 INT340212 Csf2 Positive_regulation of Pttg1ip 1 0.02 0.46 0.49 5.00
25 INT278379 Binding of Pstpip1 and Mefv 3 0.03 2.02 0.48 5.00
26 INT291018 Binding of NSF and USE1 1 0.03 0.98 0.46 5.00
27 INT230437 Binding of PDX1 and HRCT1 1 0.04 2.45 0.43 5.00
28 INT332701 Binding of BDKRB1 and BDKRB2 1 0.01 0.5 0.39 5.00
29 INT332707 Binding of TRGC1 and Klk1 1 0.32 1.64 0.36 5.00
30 INT230438 Binding of PDX1 and HAUS7 1 0.02 2.29 0.35 5.00
31 INT322208 HRCT1 Positive_regulation of PDX1 1 0.01 1.31 0.34 5.00
32 INT317835 Nlrp3 Positive_regulation of Il18 1 0.08 1.49 0.31 5.00
33 INT278018 Gh Negative_regulation of Phosphorylation of Ins1 1 0.13 1.5 0.29 5.00
34 INT278015 Gh Regulation of Ins1 1 0.10 1.47 0.27 5.00
35 INT278012 Gh Positive_regulation of Gene_expression of Ins1 1 0.11 1.24 0.26 5.00
36 INT177961 Binding of CCR3 and CCL11 1 0.04 0.73 0.26 5.00
37 INT278016 Gh Positive_regulation of Localization of Ins1 1 0.16 1.22 0.26 5.00
38 INT291019 Negative_regulation of Binding of NSF and USE1 1 0.03 0.59 0.26 5.00
39 INT235013 Binding of DSG1 and Adam17 1 0.07 1.34 0.26 5.00
40 INT234980 Positive_regulation of Egfr Positive_regulation of Adam17 1 0.09 1.33 0.26 5.00
41 INT206763 Binding of CSF2 and Nqo1 1 0.00 1.7 0.25 5.00
42 INT177957 CCL11 Regulation of Binding of IL5 and CCL11 1 0.01 0.71 0.25 5.00
43 INT177960 Binding of IL5 and CCL11 1 0.03 0.71 0.25 5.00
44 INT239087 Binding of SST and Negative_regulation of Localization of GH1 1 0.19 0.36 0.24 5.00
45 INT332700 Binding of F12 and KNG1 1 0.15 1.05 0.21 5.00
46 INT197811 Binding of SMS and SST 1 0.00 0.98 0.21 5.00
47 INT302712 Binding of Hprt and Hrh1 1 0.25 1.07 0.2 5.00
48 INT234992 Car2 Positive_regulation of Jup 1 0.02 0.27 0.2 5.00
49 INT317831 Binding of Mefv and Nlrx1 1 0.00 1.77 0.2 5.00
50 INT177962 IL4 Positive_regulation of VCAM1 1 0.02 0.97 0.2 5.00
51 INT235014 Car2 Positive_regulation of DSP 1 0.06 0.28 0.2 5.00
52 INT302711 Binding of Hrh1 and Spnb4 1 0.18 1.07 0.2 5.00
53 INT301083 Binding of BCS1L and MYH7 1 0.36 1.53 0.19 5.00
54 INT329068 Tlr9 Positive_regulation of Localization of IFNA1 1 0.03 1.54 0.19 5.00
55 INT318305 Binding of NOD2 and NLRP3 1 0.08 1.76 0.15 5.00
56 INT239081 Binding of GH1 and MAS1 1 0.03 1.41 0.15 5.00
57 INT318306 Binding of DPEP1 and NLRP3 1 0.03 1.77 0.15 5.00
58 INT278020 Binding of Gh and Sst 1 0.18 0.16 0.15 5.00
59 INT197712 Binding of HTLVR and ATF7IP 1 0.01 0.55 0.12 5.00
60 INT331612 ETV4 Positive_regulation of Gene_expression of TGFB1 1 0.00 1.32 0.12 5.00
61 INT199436 Binding of Capns1 and Cysltr1 1 0.00 0.79 0.1 5.00
62 INT199667 Cep290 Regulation of Atf4 1 0.04 1.96 0.09 5.00
63 INT277890 Binding of Ids and Tas2r111-ps2 1 0.08 0.5 0.09 5.00
64 INT277889 Regulation of Binding of Ids and Tas2r111-ps2 1 0.09 0.5 0.09 5.00
65 INT322207 CCL18 Regulation of Gene_expression of COL7A1 1 0.07 0.88 0.09 5.00
66 INT199666 Cntln Regulation of Atf4 1 0.00 1.95 0.09 5.00
67 INT291040 Binding of CFH and INS 1 0.25 1.32 0.08 5.00
68 INT232917 Binding of KRT8 and KRT19 2 0.16 1.04 0.08 5.00
69 INT331626 Edn1 Positive_regulation of Itk 1 0.00 0.57 0.07 5.00
70 INT331629 Binding of TGFB1 and Positive_regulation of Gene_expression of Itk 1 0.00 0.84 0.07 5.00
71 INT320888 Binding of olt and HCC 1 0.00 1.62 0.06 5.00
72 INT234968 IgG Negative_regulation of Jup 1 0.02 1.09 0.06 5.00
73 INT224922 Binding of FAP and TARM1 1 0.06 1.4 0.06 5.00
74 INT322206 CCL18 Positive_regulation of Gene_expression of COL7A1 1 0.05 0.28 0.05 5.00
75 INT329045 Binding of Unc93b1 and Tlr3 1 0.03 0.7 0.05 5.00
76 INT235006 IgG Positive_regulation of SRC 1 0.01 0.82 0.05 5.00
77 INT235010 Positive_regulation of Positive_regulation of SRC 1 0.01 0.84 0.05 5.00
78 INT290676 Binding of CEACAM3 and MUC16 1 0.10 0.7 0.05 5.00
79 INT232914 Binding of KRT2 and KRT7 1 0.15 0.63 0.05 5.00
80 INT232916 Binding of KRT2 and KRT19 1 0.21 0.62 0.05 5.00
81 INT232907 Binding of KRT7 and KRT8 1 0.09 0.63 0.05 5.00
82 INT234990 Binding of Cish and Dsp 1 0.01 0.24 0.04 5.00
83 INT235003 Binding of NKS1 and Rdh2 1 0.00 0.18 0.04 5.00
84 INT234986 Binding of Rdh2 and Dsp 1 0.00 0.24 0.04 5.00
85 INT327162 Binding of SERPING1 and F12 1 0.05 0.29 0.04 5.00
86 INT234994 Binding of NKS1 and Dsg3 1 0.00 0.5 0.04 5.00
87 INT235012 Binding of NKS1 and Dsp 1 0.00 0.24 0.04 5.00
88 INT234998 Binding of NKS1 and Cish 1 0.00 0.18 0.04 5.00
89 INT234991 Binding of Dsg3 and Positive_regulation of Pik3r1 1 0.05 0.32 0.03 5.00
90 INT234981 Binding of Dsg3 and Negative_regulation of Gsk3b 1 0.07 0.3 0.03 5.00
91 INT234984 Binding of Dsg3 and Positive_regulation of Akt1 1 0.03 0.32 0.03 5.00
92 INT234978 Binding of Dsg3 and Positive_regulation of Inppl1 1 0.00 0.32 0.03 5.00
93 INT199665 Binding of Fxn and Lamtor3 1 0.00 0.16 0.03 5.00
94 INT234975 Binding of Dsg3 and Negative_regulation of Gsk3a 1 0.03 0.3 0.03 5.00
95 INT235004 Binding of PKP1 and Dsp 1 0.00 0.14 0 5.00
96 INT197808 Binding of MEN1 and NME1 1 0.00 1.81 0 5.00
97 INT289293 Binding of CD59 and Cd33 1 0.02 1.06 0 5.00
98 INT234995 Binding of CDH16 and Jup 1 0.00 0.27 0 5.00
99 INT277892 IDS Regulation of Ids 1 0.18 0.41 0 5.00
100 INT351466 NMD3 Positive_regulation of Protein_catabolism of UPF1 1 0.00 0.54 0 5.00
101 INT352175 USE1 Regulation of NAGA 1 0.01 0.33 0 5.00
102 INT234972 IgG Positive_regulation of Gene_expression of Dsg3 1 0.05 0.8 0 5.00
103 INT235002 Negative_regulation of Binding of DSG1 and Dsg3 1 0.13 1.08 0 5.00
104 INT197809 Binding of MEN1 and VIM 1 0.04 0.52 0 5.00
105 INT232918 Binding of KRT2 and KRT8 1 0.17 0.59 0 5.00
106 INT278014 Ptprf Regulation of Localization of Gh 1 0.61 0.31 0 5.00
107 INT205989 Binding of SLC7A7 and PDAP1 1 0.02 1.77 0 5.00
108 INT272300 Binding of LPA and PLG 1 0.09 0.66 0 5.00
109 INT235011 Ctnnd1 Positive_regulation of RAC1 1 0.00 0.07 0 5.00
110 INT290678 Binding of CHI3L1 and KRTAP19-9P 1 0.08 1.2 0 5.00
111 INT197810 Binding of MEN1 and MUC1 1 0.06 0.47 0 5.00
112 INT272301 Negative_regulation of Binding of LPA and PLG 1 0.08 0.68 0 5.00
113 INT224921 Binding of TTR and TARM1 1 0.06 1.06 0 5.00
114 INT289301 Binding of CD59 and Cd24a 1 0.02 1.06 0 5.00
115 INT234969 Jup Regulation of Gene_expression of Dsp 1 0.01 0.54 0 5.00
116 INT197816 Binding of MEN1 and NFKB1 1 0.05 0.07 0 5.00
117 INT235007 Binding of DSG1 and Jup 1 0.08 0.36 0 5.00
118 INT197813 Binding of AMBP and MEN1 1 0.00 0.51 0 5.00
119 INT197713 CNTN2 Positive_regulation of ABCB1 1 0.01 0.34 0 5.00
120 INT234996 Ctnnd1 Positive_regulation of CDC42 1 0.01 0.07 0 5.00
121 INT235005 Positive_regulation of Binding of DSG1 and Jup 1 0.08 0.36 0 5.00
122 INT234985 Binding of Dsg3 and Pitx3 1 0.00 0.3 0 5.00
123 INT331611 NKX2-1 Regulation of Transcription of SFTPB 1 0.01 0.49 0 5.00
124 INT239406 Binding of MTTP and TAOK1 1 0.02 0.51 0 5.00
125 INT197812 Binding of AMBP and RDBP 1 0.00 0.51 0 5.00
126 INT234979 IgG Negative_regulation of Binding of Dsg3 1 0.06 1.59 0 5.00
127 INT234983 IgG Positive_regulation of Protein_catabolism of Jup 1 0.03 0.61 0 5.00
128 INT232912 Binding of KRT4 and KRT13 1 0.07 0.06 0 5.00
129 INT232910 Binding of KRT12 and KRT76 1 0.39 0.2 0 5.00
130 INT197817 Binding of JUND and MEN1 1 0.18 0.14 0 5.00
131 INT301082 Binding of BCS1L and TARM1 1 0.17 1.21 0 5.00
132 INT234970 Binding of Jup and Lat 1 0.01 0 0 5.00
133 INT239407 Binding of MTTP and PADI1 1 0.23 0.5 0 5.00
134 INT232911 Binding of KRT18 and PLAT 1 0.05 1.3 0 5.00
135 INT235019 Binding of DSC1 and DSP 1 0.39 0.07 0 5.00
136 INT235018 Binding of DSP and GOPC 1 0.02 0.19 0 5.00
137 INT197844 Binding of MEN1 and Nfkb1 1 0.06 0.26 0 5.00
138 INT234997 Binding of DSG1 and Car2 1 0.03 0.1 0 5.00
139 INT232915 Binding of KRT8 and PLAT 1 0.04 1.3 0 5.00
140 INT235000 IgG Negative_regulation of DSG1 1 0.04 0.86 0 5.00
141 INT232909 Binding of KRT1 and KRT9 1 0.16 0.5 0 5.00
142 INT234987 Binding of Jup and Dsp 1 0.01 0.18 0 5.00
143 INT277891 Binding of TPBG and M6pr-ps 1 0.02 0.06 0 5.00
144 INT290679 Binding of SPP1 and KRTAP19-9P 1 0.05 1.2 0 5.00
145 INT289295 Binding of CD59 and Fcgr3 1 0.01 1.06 0 5.00
146 INT354789 Tnc Regulation of HSPG2 1 0.02 1.38 0 5.00
147 INT289300 Binding of CD59 and Fut4 1 0.01 1.06 0 5.00
148 INT188164 Binding of ALPP and HIVEP1 1 0.02 1.15 0 5.00
149 INT290675 SPP1 Positive_regulation of Gene_expression of VEGFA 1 0.16 2.37 0 5.00
150 INT231519 Binding of PAX7 and POMT1 1 0.02 0.78 0 5.00
151 INT351465 PRSS1 Regulation of Gene_expression of IKBKAP 1 0.00 0.65 0 5.00
152 INT193193 Binding of CRS and RAPH1 1 0.12 1.47 0 5.00
153 INT239408 Binding of PADI1 and TAOK1 1 0.01 0.51 0 5.00
154 INT234999 IgG Positive_regulation of Gene_expression of DSG1 1 0.05 0.8 0 5.00
155 INT177958 IGHE Positive_regulation of TNF 1 0.03 2.23 0 5.00
156 INT235015 Binding of DSP and Dsp 1 0.02 0.25 0 5.00
157 INT192044 Binding of DSP and Jup 2 0.24 2.39 0 5.00
158 INT235008 Binding of DSG1 and Dsg3 1 0.11 4.82 0 5.00
159 INT234974 Binding of Lat and Dsp 1 0.00 0 0 5.00
160 INT197815 Binding of MEN1 and TGFB1 1 0.16 0.13 0 5.00
161 INT332159 Gh Positive_regulation of Gene_expression of Igfbp3 1 0.07 1.11 0 5.00
162 INT278017 Ptprf Regulation of Igf1 1 0.48 0.31 0 5.00
163 INT232913 Binding of KRT3 and NBPF14 1 0.01 0.21 0 5.00
164 INT234988 Negative_regulation of Binding of Dsg3 and IgG 1 0.04 0.83 0 5.00
165 INT289299 Binding of CD59 and Cd14 1 0.02 1.06 0 5.00
166 INT234989 IgG Positive_regulation of Positive_regulation of Car2 1 0.01 0.98 0 5.00
167 INT234993 Binding of Car2 and Dsp 1 0.00 0 0 5.00
168 INT232908 Binding of KRT19 and PLAT 1 0.05 1.31 0 5.00
169 INT232906 Binding of KRT1 and KRT10 1 0.18 0.51 0 5.00
170 INT177959 Positive_regulation of IGHE Positive_regulation of TNF 1 0.03 2.23 0 5.00
171 INT284184 Binding of Akt1 and Pdgfrb 1 0.00 0.14 0 5.00
172 INT234966 Phosphorylation of Jup Regulation of Binding of DSP and Jup 1 0.03 0.49 0 5.00
173 INT234982 Binding of Jup and Pkp1 1 0.00 0 0 5.00
174 INT235001 Binding of PKP1 and Sergef 1 0.01 0.06 0 5.00
175 INT235021 PKP1 Regulation of CDC42EP5 1 0.00 0.06 0 5.00
176 INT320887 Binding of TP63 and olt 1 0.01 2.15 0 5.00
177 INT234967 Binding of Dsg3 and IgG 1 0.03 0.83 0 5.00
178 INT197814 Binding of MEN1 and RELA 1 0.42 0.07 0 5.00
179 INT235016 IgG Negative_regulation of Binding of DSG1 1 0.04 2.89 0 5.00
180 INT231520 Binding of PAX7 and GOPC 1 0.09 0.98 0 5.00
181 INT235009 Binding of DSG1 and Cdh1 1 0.02 0.87 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Rare Diseases. They are ordered first by their pain relevance and then by number of times they were reported in Rare Diseases. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT340200 Negative_regulation of Smyd5 1 0.07 1.1 0.43 100.00
2 INT133214 Regulation of PDX1 9 0.34 10.26 3.36 100.00
3 INT136074 Regulation of ELOVL1 5 0.23 3.6 0.49 100.00
4 INT94146 Regulation of SPTLC1 2 0.51 2.39 0.36 100.00
5 INT157991 Regulation of Fgf12 2 0.25 4.11 0.09 100.00
6 INT205994 Transcription of SLC7A7 2 0.70 1.44 0.05 100.00
7 INT28951 Negative_regulation of IGF1 133 0.59 75.77 18.9 99.76
8 INT1893 Localization of Gh 1041 0.79 340.23 256.58 99.72
9 INT2640 Gene_expression of Pomc 424 0.78 120.72 155.37 99.68
10 INT3880 Negative_regulation of Serping1 54 0.58 37.19 4.75 99.68
11 INT128794 Negative_regulation of Gene_expression of HBB 1 0.59 5.98 0.06 99.38
12 INT16618 Negative_regulation of SERPING1 81 0.59 86.28 7.17 99.32
13 INT128793 Gene_expression of HBB 16 0.78 10.69 0.42 99.10
14 INT239410 Regulation of Localization of APOB 1 0.25 0.52 0 98.82
15 INT162564 Gene_expression of KRT2 5 0.59 1.75 0.24 98.80
16 INT232987 Gene_expression of KRT85 1 0.10 1.2 0.11 98.64
17 INT900 Localization of SLC3A2 3 0.70 2.43 0.29 98.60
18 INT228154 Gene_expression of DNAAF1 9 0.57 1.23 0.82 98.36
19 INT111051 Negative_regulation of Nav1 64 0.59 25.51 47.27 98.24
20 INT145975 Binding of TUBA1B 1 0.36 1.2 0.09 98.12
21 INT145976 Positive_regulation of TUBA1B 1 0.49 1.2 0.09 98.12
22 INT27269 Localization of Ghrh 29 0.76 15.42 2.19 98.06
23 INT239411 Localization of APOB 10 0.76 5.71 0.04 98.06
24 INT116763 Gene_expression of IKBKAP 63 0.78 54.53 0.79 97.68
25 INT116760 Gene_expression of Ikbkap 2 0.75 0.95 0.11 97.68
26 INT5871 Binding of IFNA2 38 0.48 20.35 6.46 97.44
27 INT189130 Regulation of AIS 11 0.39 7.64 0.99 97.44
28 INT76336 Negative_regulation of PDE5A 192 0.59 112.02 20.09 96.80
29 INT194022 Negative_regulation of RQCD1 4 0.33 3.18 0.13 96.80
30 INT340209 Negative_regulation of Frg1 1 0.01 0.52 0.6 96.76
31 INT274601 Regulation of PSTPIP1 3 0.45 3.76 0.28 96.72
32 INT176618 Gene_expression of HEY1 29 0.59 36 4.37 96.40
33 INT6557 Gene_expression of Eno2 65 0.77 54.42 8.17 95.80
34 INT47459 Gene_expression of Rac1 101 0.68 45.27 24.33 95.76
35 INT285 Positive_regulation of Salpa1 73 0.68 61.47 9.19 95.36
36 INT222205 Positive_regulation of PSTPIP1 8 0.69 4.69 0.62 95.36
37 INT351509 Positive_regulation of IKBKAP 19 0.70 29.01 0.63 95.16
38 INT57562 Gene_expression of GLA 52 0.77 24.62 6.14 94.92
39 INT229743 Negative_regulation of AOC2 2 0.42 2.03 0.21 94.80
40 INT1498 Gene_expression of Gh 521 0.75 220.84 81.16 94.40
41 INT251815 Negative_regulation of SPECC1 1 0.37 1.95 0.04 94.40
42 INT649 Positive_regulation of Afp 10 0.55 6.5 0.62 93.96
43 INT3987 Positive_regulation of IGHE 316 0.70 283.2 40.16 93.60
44 INT19158 Gene_expression of PAH 35 0.65 35.81 3.88 93.60
45 INT15982 Positive_regulation of NLRP3 25 0.65 23.19 3.57 93.28
46 INT73731 Binding of RAPH1 9 0.33 14.58 0.5 93.12
47 INT8792 Gene_expression of GBA 20 0.78 14.73 1.98 92.88
48 INT69478 Negative_regulation of GBA 16 0.55 7.9 0.59 92.88
49 INT351501 Regulation of IKBKAP 18 0.62 12.5 0 92.56
50 INT49311 Binding of Hprt 3 0.26 0.95 0.26 92.48
51 INT16997 Binding of PRTN3 34 0.48 33.44 6.45 90.84
52 INT14740 Gene_expression of TGFB1 272 0.78 168.48 60.18 90.76
53 INT56342 Gene_expression of TTR 34 0.78 16.5 2.05 89.88
54 INT9801 Regulation of TTR 3 0.45 1.4 0.48 89.88
55 INT231524 Localization of PAX7 5 0.56 4.2 0.39 89.28
56 INT52899 Positive_regulation of TNFRSF1A 16 0.46 19.04 3.34 89.20
57 INT149669 Positive_regulation of MEFV 12 0.46 14.17 2.07 88.40
58 INT531 Gene_expression of GH1 376 0.75 193.45 46.24 88.40
59 INT34741 Positive_regulation of Gene_expression of GH1 58 0.67 35.06 7.8 88.40
60 INT955 Gene_expression of GHRH 126 0.78 59.91 20.74 88.08
61 INT116762 Positive_regulation of Gene_expression of IKBKAP 10 0.70 9.79 0.19 87.96
62 INT351520 Negative_regulation of Gene_expression of IKBKAP 9 0.59 6.4 0.06 87.96
63 INT11340 Positive_regulation of SLC17A5 120 0.67 113.52 14.5 87.68
64 INT11823 Positive_regulation of GGT1 53 0.67 45.84 7.55 87.68
65 INT3823 Positive_regulation of ALPI 27 0.69 19.49 2.15 87.68
66 INT10248 Gene_expression of KRT20 436 0.78 231.96 32.88 86.68
67 INT19472 Gene_expression of Il1 554 0.76 419.75 175.35 86.64
68 INT98018 Protein_catabolism of FGF23 2 0.65 1.58 0.17 85.16
69 INT82646 Gene_expression of malformation 1 0.35 1.06 0.07 85.04
70 INT6512 Gene_expression of PTH 103 0.77 76.29 6.33 84.56
71 INT46383 Negative_regulation of TRGC1 42 0.55 44.03 6.2 84.56
72 INT197720 Negative_regulation of HTLVR 8 0.05 1.75 0.27 84.24
73 INT11325 Gene_expression of HLA-E 209 0.76 98.05 33.72 84.04
74 INT174195 Negative_regulation of HLA-E 31 0.42 11.98 3.88 84.04
75 INT197053 Negative_regulation of Binding of HLA-E 1 0.20 1.07 0.12 84.04
76 INT4873 Positive_regulation of FCGR3A 21 0.49 14.35 2.89 83.72
77 INT59121 Positive_regulation of MYOM2 2 0.17 1.51 0.09 83.72
78 INT48219 Gene_expression of SLC4A1 34 0.75 33.18 2.84 83.64
79 INT144481 Gene_expression of SERPING1 55 0.77 50.4 4.75 83.60
80 INT48217 Gene_expression of SLC4A3 22 0.75 21.12 2.17 83.48
81 INT37351 Negative_regulation of IKBKAP 16 0.58 9.6 0.56 83.44
82 INT1902 Gene_expression of Cck 348 0.78 70.33 241.92 83.20
83 INT2365 Positive_regulation of Cck 354 0.70 87.8 277.41 83.20
84 INT81211 Transcription of Rac1 4 0.54 1.05 0.89 83.08
85 INT340203 Regulation of Smyd5 1 0.07 1.5 1.34 82.80
86 INT78190 Gene_expression of Tnc 10 0.75 21.23 2.91 82.48
87 INT195080 Positive_regulation of Tnc 4 0.45 26.67 2.34 82.48
88 INT11699 Binding of HLA-E 85 0.47 52.51 13.41 82.36
89 INT17739 Gene_expression of S100B 226 0.78 132.7 26.4 82.16
90 INT95944 Binding of Fgf12 11 0.28 8.98 2.53 82.00
91 INT59120 Gene_expression of MYOM2 2 0.22 2.81 0.25 81.96
92 INT3361 Positive_regulation of Esr1 273 0.69 208.53 44.81 81.72
93 INT12243 Positive_regulation of PRSS1 91 0.70 52.87 19.48 80.80
94 INT36554 Gene_expression of PRSS1 70 0.78 50.25 15.33 80.80
95 INT89 Positive_regulation of Gast 187 0.70 80.49 42.07 80.32
96 INT84026 Positive_regulation of SLC7A7 8 0.67 3.12 0.33 79.76
97 INT55114 Gene_expression of CRS 42 0.58 26.86 4.69 79.68
98 INT168374 Negative_regulation of Capns1 2 0.50 5.09 1.1 79.44
99 INT6810 Gene_expression of ENO2 70 0.78 54.8 8.35 78.84
100 INT60423 Positive_regulation of TPSG1 11 0.57 11.02 2.55 78.40
101 INT199433 Negative_regulation of LTA 5 0.17 3.84 0.74 78.40
102 INT199640 Positive_regulation of Positive_regulation of Fxn 2 0.41 2.97 0.14 78.28
103 INT144482 Negative_regulation of Gene_expression of SERPING1 8 0.43 6.06 0.89 78.16
104 INT199642 Positive_regulation of Fxn 3 0.41 3.6 0.14 78.00
105 INT74443 Positive_regulation of PML 11 0.53 12.52 1.21 77.84
106 INT25607 Binding of Il1 82 0.47 64.4 23.9 77.68
107 INT124191 Localization of SDHB 3 0.74 2.4 0.32 77.28
108 INT257453 Positive_regulation of USE1 12 0.20 6.7 0.94 76.64
109 INT892 Regulation of TRH 23 0.60 8.46 8.54 76.56
110 INT62061 Gene_expression of TRGC1 32 0.69 17.43 3.37 76.56
111 INT314337 Negative_regulation of Gene_expression of TRGC1 3 0.52 5.24 0.8 76.56
112 INT64843 Gene_expression of Serping1 19 0.67 8.88 2.72 75.68
113 INT756 Gene_expression of C3 138 0.75 100.6 19.2 75.00
114 INT3550 Negative_regulation of GLA 52 0.59 33.93 5.26 75.00
115 INT124438 Regulation of Gene_expression of Slc6a4 9 0.62 3.5 2.97 74.80
116 INT90 Localization of Gast 400 0.81 137.67 113 74.76
117 INT239412 Binding of ABL1 8 0.28 5.39 0.18 74.68
118 INT75932 Binding of Csf2 45 0.37 33.2 8.01 74.40
119 INT29674 Gene_expression of Ada 16 0.78 4.59 5.69 74.24
120 INT147584 Localization of AIS 38 0.63 12.83 5.27 74.08
121 INT133875 Gene_expression of POMT1 26 0.58 17.1 1.48 74.08
122 INT62509 Gene_expression of MCS 58 0.67 21.46 6.57 73.92
123 INT277886 Localization of Ids 3 0.73 1.09 0.48 73.84
124 INT22429 Positive_regulation of PDAP1 34 0.61 22.58 2.91 73.60
125 INT89928 Gene_expression of CSF2RA 19 0.75 6.78 1.27 73.12
126 INT188034 Positive_regulation of Gene_expression of CSF2RA 2 0.45 1.24 0.15 73.12
127 INT66423 Binding of ELOVL1 52 0.40 61.63 5.16 72.92
128 INT91775 Gene_expression of Slc6a4 102 0.78 26.45 28.23 72.56
129 INT20044 Negative_regulation of Gpi1 50 0.59 29.96 26 72.56
130 INT149138 Binding of PDX1 27 0.37 32.62 9.33 72.44
131 INT105571 Gene_expression of SRGN 33 0.58 14.68 1.19 72.32
132 INT3343 Regulation of PTH 24 0.62 11.18 1.62 72.16
133 INT192653 Binding of Capns1 8 0.26 9.94 0.51 72.08
134 INT59466 Gene_expression of ISYNA1 204 0.77 112.57 35.48 71.80
135 INT14600 Positive_regulation of Tpsab1 51 0.68 22.1 7.7 71.56
136 INT83295 Positive_regulation of Cd68 21 0.39 14.55 2.46 71.56
137 INT50740 Positive_regulation of SPG21 18 0.67 8.3 1.65 71.56
138 INT94438 Gene_expression of OLR1 86 0.78 80.38 11.03 71.40
139 INT15610 Localization of GOPC 223 0.65 68.26 28.7 70.44
140 INT169990 Localization of POMT1 7 0.19 4.09 0.45 70.44
141 INT57958 Positive_regulation of Myo5a 9 0.41 7.52 0.77 69.96
142 INT107307 Transcription of IFNA1 30 0.52 18.16 9.61 69.80
143 INT239084 Localization of KAT2B 4 0.73 3.08 0.36 69.60
144 INT239085 Binding of KAT2B 1 0.18 2.04 0.09 69.60
145 INT74726 Negative_regulation of Slc6a4 61 0.59 21.01 27.84 69.48
146 INT4853 Regulation of Hrh2 42 0.45 22.34 16.65 69.44
147 INT239082 Binding of BCAM 1 0.03 2.03 0.09 69.40
148 INT239086 Localization of BCAM 2 0.54 2.32 0.09 69.40
149 INT196994 Regulation of TMEM200A 9 0.17 2.23 0.61 69.24
150 INT105021 Binding of GOPC 187 0.40 60.39 20.38 68.80
151 INT56817 Regulation of Eno2 16 0.61 10.64 1.99 68.80
152 INT105991 Negative_regulation of IDS 12 0.38 6.31 1.04 67.36
153 INT62784 Gene_expression of NT5E 46 0.65 15.95 3.72 67.16
154 INT1624 Gene_expression of Cea 212 0.76 180.44 34.21 66.96
155 INT4146 Binding of SHBG 49 0.47 31 4.71 66.96
156 INT671 Positive_regulation of Cea 221 0.69 164.5 47.79 66.56
157 INT9408 Positive_regulation of Crp 296 0.69 242.27 57.35 65.88
158 INT14598 Gene_expression of Tpsab1 40 0.73 14.55 5.4 65.68
159 INT374 Positive_regulation of Ldha 212 0.70 107.08 47.43 65.48
160 INT5841 Gene_expression of Vim 181 0.72 138.54 16.33 65.44
161 INT11775 Gene_expression of Ema 39 0.65 38.12 2.99 65.04
162 INT205998 Binding of PDAP1 3 0.33 2.66 0.03 64.92
163 INT57699 Positive_regulation of CD1A 11 0.50 8.49 2.93 64.64
164 INT83896 Gene_expression of CD1A 19 0.68 15.58 2.1 64.64
165 INT211970 Negative_regulation of Best1 49 0.14 37.33 2.32 64.36
166 INT45668 Gene_expression of Il28b 3 0.15 2.66 0.16 64.24
167 INT95652 Gene_expression of Krt20 54 0.61 53.69 3.31 64.20
168 INT64346 Positive_regulation of S100B 95 0.70 63.11 9.17 64.00
169 INT1108 Gene_expression of PPY 58 0.75 36.57 10.76 63.92
170 INT2725 Positive_regulation of FCER2 23 0.69 23.08 4.7 63.72
171 INT317746 Positive_regulation of Gene_expression of FCER2 2 0.01 4.09 0.3 63.72
172 INT899 Gene_expression of F13A1 122 0.70 78.02 16.26 63.60
173 INT94454 Gene_expression of CD68 73 0.72 63.94 10.43 63.60
174 INT149332 Gene_expression of CD163 19 0.75 13.63 3.65 63.60
175 INT162061 Regulation of Gene_expression of FGF23 1 0.45 1.02 0.07 63.44
176 INT3375 Gene_expression of IGHE 535 0.77 387.47 65.46 63.32
177 INT32421 Gene_expression of FCER2 19 0.73 17.23 2.53 63.32
178 INT333278 Negative_regulation of Transcription of Slc6a4 2 0.37 0.56 0.36 63.20
179 INT103021 Transcription of Slc6a4 16 0.70 3.93 3.77 62.92
180 INT135274 Positive_regulation of RQCD1 2 0.36 1.24 0.08 62.40
181 INT14599 Localization of Tpsab1 36 0.79 14.58 7.18 62.36
182 INT98645 Gene_expression of FGF23 9 0.78 10.07 0.8 62.36
183 INT219136 Positive_regulation of Positive_regulation of Nlrp3 3 0.49 2.61 0.58 61.72
184 INT194023 Gene_expression of RQCD1 3 0.52 3.99 0.12 61.28
185 INT231525 Negative_regulation of Localization of PAX7 1 0.12 1.05 0.04 61.24
186 INT52937 Gene_expression of Cd68 37 0.67 31.33 7.54 60.20
187 INT277878 Binding of Ids 4 0.34 0.8 0.24 58.76
188 INT206796 Positive_regulation of VAMP7 2 0.56 4.12 0.07 58.04
189 INT36221 Positive_regulation of Nlrp3 25 0.68 19.7 4.5 57.92
190 INT36798 Gene_expression of Mki67 178 0.77 132 8.24 57.84
191 INT157960 Regulation of AQP4 11 0.48 21.36 3.06 57.68
192 INT38056 Localization of Crp 71 0.78 53.14 17.03 57.64
193 INT162 Regulation of Prl 794 0.62 165.01 322.24 57.52
194 INT16960 Gene_expression of Crp 166 0.76 116.21 34.07 57.12
195 INT105114 Gene_expression of Arigg4 16 0.52 21.88 4.56 57.12
196 INT175002 Positive_regulation of Mki67 10 0.31 5.7 0.26 57.04
197 INT277884 Binding of Tas2r111-ps2 1 0.09 0.95 0.19 56.36
198 INT62400 Positive_regulation of Localization of Il1 34 0.67 35.53 7.96 56.16
199 INT19775 Localization of Il1 183 0.78 145.5 50.91 55.92
200 INT88867 Localization of MCS 19 0.62 28.31 3.88 55.92
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