D:Relapsing Polychondritis

From wiki-pain
Jump to: navigation, search

pChart

Disease Term
Synonyms Atrophic Polychondritides Chronic, Atrophic Polychondritis Chronic, CHRONIC ATROPHIC POLYCHONDRITIDES, Chronic Atrophic Polychondritis, Chronic Polychondritis, Meyenburg Altherr Uehlinger Syndrome, Meyenburg S Disease, Myenberg Altherr Uehlinger Syndrome, Panchondritis, POLYCHONDRITIDES CHRONIC ATROPHIC, Polychondritides Relapsing
Documents 83
Hot Single Events 25
Hot Interactions 2

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Relapsing Polychondritis. They are ordered first by their relevance to Relapsing Polychondritis and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT336341 Binding of RTCA and ELOVL1 1 0.02 2.15 0.07 100.00
2 INT172022 Binding of F13A1 and FN1 1 0.00 1.33 0.24 83.88
3 INT172023 Binding of FN1 and PRTN3 1 0.00 1.05 0.37 35.60
4 INT185490 Atp5o Negative_regulation of Gene_expression of P2rx7 1 0.01 0.87 0.53 5.00
5 INT185489 Atp5o Negative_regulation of P2rx7 1 0.01 0.29 0.24 5.00
6 INT277053 Protein_catabolism of TIMP1 Positive_regulation of COL5A2 1 0.01 0.14 0.07 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Relapsing Polychondritis. They are ordered first by their pain relevance and then by number of times they were reported in Relapsing Polychondritis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT79167 Localization of TNC 8 0.78 4.15 1.44 100.00
2 INT2120 Gene_expression of CD79A 159 0.78 111.69 17.16 99.88
3 INT66423 Binding of ELOVL1 52 0.40 61.63 5.16 99.56
4 INT172070 Binding of Matn1 1 0.26 4.95 0.79 99.40
5 INT124815 Binding of Col2a1 9 0.37 10.27 3.93 99.40
6 INT13170 Gene_expression of Comp 25 0.74 8.68 5.62 99.40
7 INT13520 Binding of HLA-DRB4 30 0.42 32.65 6.74 98.60
8 INT43907 Binding of CD79A 28 0.48 28.11 3.04 98.54
9 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65 96.04
10 INT43719 Positive_regulation of Vegfa 21 0.69 5.15 2.64 96.04
11 INT105247 Positive_regulation of Gene_expression of Vegfa 12 0.67 12.07 2.05 96.04
12 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 95.52
13 INT43721 Gene_expression of Vegfa 49 0.77 36.18 6.63 95.28
14 INT172071 Positive_regulation of Binding of Matn1 1 0.35 1.53 0.29 95.16
15 INT1721 Negative_regulation of HP 148 0.42 86.82 16.89 93.88
16 INT1123 Positive_regulation of CD79A 74 0.70 51.96 7.14 90.08
17 INT71601 Positive_regulation of ACD 11 0.60 6.55 0.9 89.80
18 INT116228 Binding of C1qa 26 0.47 15.72 3 87.48
19 INT46695 Positive_regulation of TNC 28 0.67 17.06 12.04 85.56
20 INT173587 Protein_catabolism of COL5A2 59 0.32 32.73 8.96 84.96
21 INT4004 Gene_expression of IGHG3 321 0.71 221.03 42.33 84.12
22 INT61500 Binding of FN1 39 0.48 27.33 3.13 83.88
23 INT11587 Gene_expression of CSF2 645 0.78 544.38 93.89 83.12
24 INT64777 Negative_regulation of COL5A2 32 0.38 17.4 2.28 83.08
25 INT10832 Gene_expression of IL8 1050 0.78 698.72 270 80.36
26 INT171747 Gene_expression of ACD 4 0.57 4.44 0.68 76.40
27 INT144054 Gene_expression of Serpina3j 1 0.53 2.6 0.36 74.88
28 INT82878 Gene_expression of Ccl2 201 0.78 164.95 101.35 73.88
29 INT72188 Gene_expression of Cxcl10 22 0.65 12.93 15.35 73.88
30 INT185482 Binding of Cxcl10 5 0.30 3.76 3.13 73.32
31 INT106200 Binding of Ccl2 22 0.42 16.7 9.75 72.92
32 INT29094 Binding of C3 39 0.37 12.65 2.27 71.52
33 INT67279 Localization of PRTN3 11 0.50 14.18 4.3 67.36
34 INT16772 Gene_expression of MPO 81 0.78 90.98 11.9 63.48
35 INT56221 Regulation of MPO 8 0.61 8.44 1.84 63.48
36 INT270857 Protein_catabolism of ACD 1 0.07 0.77 0.07 63.20
37 INT16996 Gene_expression of PRTN3 113 0.75 85.61 22.57 57.92
38 INT16997 Binding of PRTN3 34 0.48 33.44 6.45 57.92
39 INT49519 Gene_expression of P2rx7 84 0.76 36.88 34.69 55.08
40 INT172035 Binding of HMGB2 1 0.09 1.67 0.28 51.04
41 INT173592 Binding of COL5A2 32 0.33 9.14 2.48 32.60
42 INT213669 Positive_regulation of COL4A3 2 0.00 1.24 0.23 17.56
43 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 5.00
44 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 5.00
45 INT12339 Localization of IL8 437 0.81 251.87 117.39 5.00
46 INT170025 Gene_expression of Fig4 588 0.67 183.27 113.32 5.00
47 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 5.00
48 INT171145 Positive_regulation of Fig4 274 0.59 93.55 69.81 5.00
49 INT62960 Gene_expression of P2rx2 149 0.77 58.31 59.16 5.00
50 INT48901 Negative_regulation of IL6 186 0.57 136.33 57.87 5.00
51 INT9408 Positive_regulation of Crp 296 0.69 242.27 57.35 5.00
52 INT157666 Positive_regulation of GOPC 335 0.60 120.19 42.75 5.00
53 INT52732 Negative_regulation of CRP 169 0.59 138.47 40.33 5.00
54 INT6105 Positive_regulation of IL2 133 0.69 82.76 34.67 5.00
55 INT12161 Positive_regulation of P2rx2 70 0.69 34.22 34.4 5.00
56 INT8905 Gene_expression of EDN1 215 0.78 157.1 34.19 5.00
57 INT84170 Positive_regulation of Gene_expression of Ccl2 58 0.69 48.79 32.43 5.00
58 INT9347 Localization of Il1b 58 0.81 26.13 31.53 5.00
59 INT82882 Localization of Ccl2 61 0.80 41.96 28 5.00
60 INT19856 Gene_expression of CD8A 240 0.75 147.86 26.39 5.00
61 INT5055 Positive_regulation of IFNG 89 0.69 64.03 23.05 5.00
62 INT11659 Gene_expression of COL2A1 164 0.78 78.49 22.58 5.00
63 INT11161 Gene_expression of HLA-DRB1 121 0.78 75.33 20.96 5.00
64 INT85952 Positive_regulation of AR 168 0.67 64.36 20.66 5.00
65 INT105021 Binding of GOPC 187 0.40 60.39 20.38 5.00
66 INT8662 Positive_regulation of EDN1 144 0.70 125.34 19.59 5.00
67 INT84171 Negative_regulation of Gene_expression of Ccl2 30 0.58 26.37 18.28 5.00
68 INT72564 Localization of Il10 41 0.78 28.62 17.6 5.00
69 INT143230 Gene_expression of CRYGD 61 0.65 52.11 15.93 5.00
70 INT170855 Negative_regulation of GOPC 188 0.38 70.92 15.41 5.00
71 INT8904 Positive_regulation of Gene_expression of EDN1 66 0.70 65.4 14.42 5.00
72 INT158124 Gene_expression of COL5A2 136 0.69 72.3 12.44 5.00
73 INT48335 Negative_regulation of NOSTRIN 38 0.56 16.22 12.05 5.00
74 INT73427 Localization of P2rx7 24 0.79 8.65 9.87 5.00
75 INT48257 Negative_regulation of P2rx7 18 0.41 7.82 8.42 5.00
76 INT173808 Positive_regulation of CYP27A1 35 0.68 23.7 7.87 5.00
77 INT171146 Negative_regulation of Gene_expression of Fig4 38 0.37 11.41 7.42 5.00
78 INT48626 Positive_regulation of Csf3 33 0.66 29.79 7.34 5.00
79 INT91351 Gene_expression of P2rx1 28 0.75 5.89 6.78 5.00
80 INT120261 Binding of P2rx2 19 0.28 5.8 6.72 5.00
81 INT22450 Gene_expression of GPI 31 0.58 18.77 6.71 5.00
82 INT57720 Localization of IGHG3 33 0.74 20.24 6.25 5.00
83 INT68882 Binding of P2rx7 16 0.23 4.33 6.17 5.00
84 INT91657 Negative_regulation of IL18 20 0.48 15.97 6.12 5.00
85 INT187133 Protein_catabolism of TIMP1 19 0.73 11.3 5.51 5.00
86 INT174851 Positive_regulation of COL5A2 46 0.54 12.73 5.48 5.00
87 INT53184 Negative_regulation of CYP27A1 46 0.57 16.04 5.28 5.00
88 INT45753 Localization of CD40LG 45 0.79 32.31 5.28 5.00
89 INT185484 Positive_regulation of Gene_expression of P2rx7 8 0.31 7.44 4.28 5.00
90 INT33739 Gene_expression of ITGA2B 25 0.75 8.19 3.6 5.00
91 INT14281 Gene_expression of Hspa5 44 0.63 34.19 3.31 5.00
92 INT47949 Positive_regulation of ELOVL1 19 0.42 29.78 3.3 5.00
93 INT185487 Localization of Cxcl10 6 0.61 3.21 3.21 5.00
94 INT28893 Positive_regulation of Atp5o 3 0.43 0.27 2.9 5.00
95 INT14448 Localization of COL5A2 34 0.67 17.35 2.85 5.00
96 INT41874 Positive_regulation of GPI 9 0.49 9.97 2.79 5.00
97 INT107216 Negative_regulation of Gene_expression of P2rx7 10 0.56 3.39 2.61 5.00
98 INT100492 Positive_regulation of Gene_expression of Cxcl10 5 0.49 1.71 2.56 5.00
99 INT102659 Gene_expression of CSF3 32 0.77 21.93 2.39 5.00
100 INT19131 Localization of CYP27A1 14 0.80 8.19 2.15 5.00
101 INT41775 Gene_expression of NEUROG1 10 0.71 5.46 2.14 5.00
102 INT174541 Positive_regulation of Gene_expression of COL5A2 18 0.36 14.17 2.12 5.00
103 INT48444 Localization of Csf3 28 0.72 14.85 2.11 5.00
104 INT48141 Binding of Csf3 18 0.39 9.93 1.71 5.00
105 INT51840 Positive_regulation of Localization of CD40LG 8 0.69 9.59 1.58 5.00
106 INT172041 Gene_expression of FLG 6 0.65 3.55 1.58 5.00
107 INT47950 Negative_regulation of ELOVL1 15 0.41 20.33 1.41 5.00
108 INT264337 Positive_regulation of NCOA5 4 0.03 4.28 1.23 5.00
109 INT169363 Negative_regulation of PTGIS 4 0.20 3.35 1.22 5.00
110 INT172039 Gene_expression of AFA 1 0.23 3.02 1.1 5.00
111 INT118054 Regulation of ARMC9 23 0.34 11.32 1.06 5.00
112 INT114664 Binding of BMP2 12 0.37 6.54 0.91 5.00
113 INT148291 Positive_regulation of CSF3 9 0.61 6.37 0.7 5.00
114 INT180554 Binding of NCOA5 3 0.14 2.17 0.68 5.00
115 INT277052 Negative_regulation of Abpd 1 0.42 0.91 0.68 5.00
116 INT3503 Localization of COL11A1 3 0.65 2.17 0.63 5.00
117 INT194560 Binding of Abpd 5 0.47 1.31 0.62 5.00
118 INT185485 Negative_regulation of Localization of P2rx7 1 0.26 0.95 0.62 5.00
119 INT25602 Positive_regulation of THPO 5 0.69 4.55 0.57 5.00
120 INT172043 Negative_regulation of CAST 2 0.15 1.03 0.49 5.00
121 INT172042 Positive_regulation of Gene_expression of GPI 2 0.32 1.26 0.46 5.00
122 INT150488 Gene_expression of CAST 4 0.73 1.33 0.43 5.00
123 INT185483 Gene_expression of Dhx36 1 0.01 0.12 0.38 5.00
124 INT172038 Binding of FLG 1 0.47 0.73 0.36 5.00
125 INT277061 Positive_regulation of COL11A1 2 0.43 1.56 0.28 5.00
126 INT270115 Negative_regulation of Localization of CYP27A1 2 0.02 1.11 0.26 5.00
127 INT212362 Positive_regulation of Gene_expression of CSF3 3 0.32 4.85 0.26 5.00
128 INT172046 Transcription of NEUROG1 1 0.05 0.43 0.21 5.00
129 INT185486 Gene_expression of Atp5o 1 0.02 0.14 0.21 5.00
130 INT185481 Negative_regulation of Gene_expression of Atp5o 1 0.01 0.14 0.21 5.00
131 INT172021 Localization of Hspa5 2 0.18 0.93 0.2 5.00
132 INT172044 Localization of FLG 1 0.73 0.35 0.17 5.00
133 INT172037 Regulation of FLG 1 0.08 0.24 0.12 5.00
134 INT172036 Gene_expression of PHAX 1 0.01 0.21 0.11 5.00
135 INT172034 Phosphorylation of FLG 1 0.80 0.15 0.08 5.00
136 INT172045 Protein_catabolism of FLG 1 0.64 0.15 0.08 5.00
137 INT193358 Localization of ST3GAL4 2 0.52 1.65 0.05 5.00
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox