D:Renal Cancer

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Disease Term
Synonyms Cancer Kidney, Cancer Of Kidney, Cancer Of The Kidney, CANCER RENAL, Cancers Kidney, Cancers Renal, Kidney Cancer, Kidney Cancers, Kidney Neoplasm, Kidney Neoplasms, Neoplasm Kidney
Documents 1531
Hot Single Events 200
Hot Interactions 66

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Renal Cancer. They are ordered first by their relevance to Renal Cancer and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT278068 Binding of XRCC1 and Vhl 1 0.02 2.3 0 100.00
2 INT74014 Binding of TSC1 and XRCC1 1 0.02 1.98 0.09 100.00
3 INT74015 Binding of VHL and XRCC1 1 0.07 3.51 0.09 100.00
4 INT278059 XRCC1 Positive_regulation of Gene_expression of IL2 1 0.01 1.06 0.07 100.00
5 INT260342 Binding of Esr1 and Rcc1 1 0.05 0.99 0 100.00
6 INT339096 Ezh2 Regulation of Rcc1 1 0.02 1.1 0 100.00
7 INT313886 RPS6KB1 Positive_regulation of Gene_expression of XRCC1 1 0.01 0.8 0.05 100.00
8 INT313890 Akt1 Positive_regulation of Gene_expression of XRCC1 1 0.00 0.79 0.05 100.00
9 INT268674 IL2 Positive_regulation of XRCC1 1 0.08 0.75 0.05 100.00
10 INT268677 IFNA2 Positive_regulation of XRCC1 1 0.05 0.75 0.05 100.00
11 INT313885 XRCC1 Positive_regulation of Localization of PTEN 1 0.00 0.65 0 100.00
12 INT313884 XRCC1 Positive_regulation of Localization of HIF1A 1 0.00 0.65 0 100.00
13 INT350981 VHL Regulation of XRCC1 1 0.01 1.42 0 100.00
14 INT7204 Binding of IFNA1 and IFNG 1 0.01 1.34 0.11 100.00
15 INT350984 Positive_regulation of VHL Positive_regulation of VEGFA 1 0.27 2.74 0 99.92
16 INT332795 Negative_regulation of Vhl Positive_regulation of Positive_regulation of Cxcr4 1 0.02 1.64 0.05 99.88
17 INT110855 Pkia Negative_regulation of Egf 1 0.15 1.2 0.08 99.00
18 INT110856 TXK Negative_regulation of Egf 1 0.02 1.2 0.08 98.28
19 INT244641 PDGFA Regulation of MTOR 1 0.07 2.55 0.06 98.24
20 INT315066 AKT1 Negative_regulation of PAR4 1 0.39 1.8 0.03 97.64
21 INT237921 ROS1 Positive_regulation of TNFRSF10B 1 0.08 1.24 0.03 97.20
22 INT196523 Binding of MMP2 and TIMP1 3 0.43 1.94 0.85 97.04
23 INT268679 Binding of HDAC1 and NCOR2 3 0.17 2.8 0.07 96.72
24 INT268673 Binding of NCOR2 and BCOR 1 0.01 2.54 0.07 96.72
25 INT268675 Binding of NCOR2 and SIN3A 1 0.27 2.54 0.07 96.72
26 INT268678 Binding of HDAC2 and NCOR2 1 0.18 2.67 0.07 96.72
27 INT196526 Binding of TIMP1 and TIMP2 1 0.45 1.49 0.71 95.52
28 INT268676 Binding of HDAC1 and BCOR 1 0.01 1.31 0.04 95.20
29 INT241120 Binding of Sdhc and Sdhd 1 0.00 1.28 0 94.88
30 INT178986 Binding of MMP9 and TIMP1 4 0.47 2.58 1.33 94.72
31 INT315068 Binding of AKT1 and PAR4 1 0.34 4.41 0 94.48
32 INT347257 Binding of LOX and PPARA 1 0.15 0.6 0 94.16
33 INT241119 Binding of Sdhc and Sdhb 1 0.00 1.29 0 94.16
34 INT347258 PPARA Negative_regulation of Localization of VEGFA 1 0.16 1.36 0 93.80
35 INT279145 Binding of VHL and RNF139 1 0.30 1.87 0 93.60
36 INT191814 PDLIM7 Positive_regulation of TNFRSF8 1 0.08 1.16 0.08 93.60
37 INT191813 PDLIM7 Positive_regulation of FUT4 1 0.09 1.16 0.08 93.60
38 INT244116 ELAVL3 Negative_regulation of MUC1 1 0.09 3.41 0.15 93.36
39 INT267156 Binding of VDR and SUGT1 1 0.04 3.4 0.09 93.08
40 INT244640 AGK Negative_regulation of KIT 1 0.00 0.69 0.08 92.88
41 INT245074 Gene_expression of VHL Negative_regulation of Gene_expression of CXCR4 1 0.31 1.84 0 92.40
42 INT244639 AGK Negative_regulation of PDGFRB 1 0.01 0.69 0.08 92.00
43 INT315868 Vhl Positive_regulation of Transcription of PDGFA 1 0.00 1.39 0 91.40
44 INT315867 Vhl Positive_regulation of Transcription of VEGFA 1 0.01 1.39 0 91.40
45 INT124405 Binding of SST and SSTR1 1 0.01 0.5 0.41 91.36
46 INT244638 AGK Negative_regulation of KDR 1 0.00 0.68 0.08 91.12
47 INT87026 ZAK Positive_regulation of Gene_expression of IL12A 3 0.12 2.55 1.26 88.80
48 INT213816 Binding of Tcf12 and Tfeb 1 0.01 1.91 0.27 88.16
49 INT213801 Binding of Tcf12 and Tfe3 1 0.01 1.11 0.03 88.16
50 INT350982 TSHB Regulation of VEGFA 1 0.01 0.64 0 88.16
51 INT210707 Binding of IFNA2 and IL2 1 0.06 0.91 0 87.68
52 INT196436 Cdk4 Negative_regulation of Ccnd1 Positive_regulation of Ccnd1 1 0.04 1.18 0.13 87.52
53 INT312372 Binding of MME and TCHP 1 0.06 1.56 0 86.44
54 INT196433 Cdk4 Negative_regulation of Ccnd1 1 0.10 1.17 0.13 86.32
55 INT213803 Binding of Foxm1 and Tfe3 1 0.00 1.09 0.03 86.24
56 INT213810 Binding of Foxm1 and Tfeb 1 0.00 1.09 0.03 86.24
57 INT351098 MTOR Regulation of Binding of EPAS1 1 0.08 0.95 0 85.32
58 INT334323 IL8 Positive_regulation of EGFR 1 0.50 1.29 0 85.28
59 INT334319 IL8 Positive_regulation of MAPK1 1 0.25 1.29 0 85.28
60 INT350980 ESR1 Regulation of VEGFA 1 0.01 0.62 0 84.96
61 INT279144 RNF139 Regulation of TSN 1 0.24 3.47 0 83.08
62 INT350983 TP53 Regulation of VEGFA 1 0.03 0.61 0 82.72
63 INT315061 PAR4 Positive_regulation of Gene_expression of TNF 1 0.10 1.95 0 81.20
64 INT149117 Binding of CD80 and CTLA4 31 0.52 12.7 7.73 81.08
65 INT299754 Binding of APC and CTLA4 2 0.08 0.97 0.11 81.08
66 INT34727 TNF Positive_regulation of Gene_expression of IL2 1 0.56 0.81 0.31 80.44
67 INT236235 HLA-A Positive_regulation of CD8A 1 0.01 1 0.03 78.80
68 INT237979 PPARA Negative_regulation of Birc5 1 0.49 1.26 0 78.24
69 INT291329 Binding of NOTCH1 and CERS1 1 0.06 1.42 0 77.68
70 INT194647 Binding of CD28 and CD80 15 0.40 4.9 3.22 76.80
71 INT301674 Binding of APC and CD80 1 0.01 0.53 0 76.56
72 INT178503 Binding of Cd36 and ecs 1 0.01 0.34 0.04 75.44
73 INT211883 Binding of RET and CDCP1 1 0.00 2.12 0 75.28
74 INT211882 Binding of KIT and CDCP1 1 0.00 2.1 0 75.28
75 INT291330 Binding of ENO1 and NOTCH1 1 0.03 1.33 0 74.96
76 INT291333 Binding of CSHL1 and NOTCH1 1 0.05 1.16 0 72.64
77 INT331172 Binding of IFNA1 and IL2 1 0.00 0.46 0.04 72.24
78 INT213800 Kit Positive_regulation of Mitf 1 0.30 1.24 0.15 71.48
79 INT213797 Kit Positive_regulation of Tfe3 1 0.28 1.24 0.14 71.48
80 INT213817 Phosphorylation of Tfe3 Positive_regulation of Mitf 1 0.22 1.22 0.15 70.20
81 INT213811 Tfe3 Positive_regulation of Spg21 1 0.05 1.21 0.15 68.24
82 INT213807 Mitf Positive_regulation of Spg21 1 0.05 1.2 0.15 67.88
83 INT168549 Binding of MME and NCAM1 1 0.00 1.43 0.08 67.84
84 INT315856 FLT3 Positive_regulation of Gene_expression of PDGFA 1 0.01 1.15 0 65.16
85 INT299295 OR3A4P Negative_regulation of Phosphorylation of AKT1 1 0.00 0.22 0 64.40
86 INT183721 HPN Positive_regulation of MYO7A 1 0.02 1.55 0 64.00
87 INT218784 Binding of TCEB2 and VHL 1 0.04 3.81 0.1 61.60
88 INT178502 Col18a1 Negative_regulation of ecs 1 0.01 0.52 0.03 59.68
89 INT200212 Binding of EPAS1 and VHL 3 0.06 4.1 0.05 58.88
90 INT299282 PTPN3 Negative_regulation of Positive_regulation of RPTOR 1 0.07 0.48 0.67 58.68
91 INT299264 PTPN3 Negative_regulation of VEGFA Positive_regulation of PI3 1 0.03 0.12 0.05 58.68
92 INT262809 Il10 Positive_regulation of Regulation of Slc11a1 1 0.17 1.12 0.27 58.20
93 INT208152 Binding of CDK4 and MDM2 1 0.01 1.11 0 57.36
94 INT292088 Binding of AMELX and ANGPT1 1 0.00 0.9 0 57.28
95 INT309906 Binding of EGF and SRC 1 0.11 0.64 0 57.00
96 INT299299 VEGFA Positive_regulation of SRC 1 0.20 0.91 1.2 56.88
97 INT299286 VEGFA Positive_regulation of PI3 1 0.16 0.46 0.6 56.88
98 INT258529 Binding of JAG1 and NOTCH1 3 0.06 2.44 0 54.88
99 INT258528 Binding of NOTCH1 and DLL1 2 0.07 1.6 0 54.16
100 INT272013 Binding of OGG1 and Tsc2 1 0.09 0.67 0 53.20
101 INT299302 Negative_regulation of RPTOR Regulation of AKT1 1 0.30 0.1 0.05 51.76
102 INT327336 Binding of VEGFA and Elavl1 1 0.06 0.94 0.04 51.36
103 INT299304 RPTOR Regulation of AKT1 1 0.19 0.1 0.05 50.84
104 INT232911 Binding of KRT18 and PLAT 1 0.05 1.3 0 49.56
105 INT232915 Binding of KRT8 and PLAT 1 0.04 1.3 0 49.56
106 INT232908 Binding of KRT19 and PLAT 1 0.05 1.31 0 49.56
107 INT190045 Binding of Ebp and Scrib 1 0.10 0.79 0.22 49.28
108 INT190052 Binding of Cdx2 and Ebp 1 0.08 0.82 0.24 48.80
109 INT258564 Binding of NOTCH1 and Crlf2 1 0.27 0.67 0 47.84
110 INT262752 IGHA1 Positive_regulation of IGKV2D-19 1 0.00 1.39 0 46.44
111 INT262810 Slc11a1 Positive_regulation of Gene_expression of Il10 1 0.20 0.97 0.27 44.72
112 INT237980 CCND3 Regulation of Gene_expression of Birc5 1 0.06 0.96 0 42.68
113 INT218785 Binding of FN1 and VHL 1 0.06 1.12 0 42.20
114 INT285290 TNF Positive_regulation of Gene_expression of H2-D1 1 0.01 1.41 0.06 40.96
115 INT116124 Binding of AFP and HCC 2 0.20 1.72 0.15 40.48
116 INT87025 ZAK Positive_regulation of Gene_expression of IL6 2 0.11 1.59 1.02 40.16
117 INT87023 ZAK Positive_regulation of Gene_expression of IL36RN 1 0.03 0.62 0.36 38.96
118 INT351099 EPAS1 Regulation of Gene_expression of CRTC1 1 0.00 0.8 0 38.80
119 INT272010 Tsc2 Negative_regulation of OGG1 1 0.17 0.6 0 37.52
120 INT213814 F3 Positive_regulation of Pars2 1 0.01 0.58 0.21 36.08
121 INT334423 Binding of SPINK1 and Cea 1 0.02 2.53 0.17 35.84
122 INT237920 PPARA Negative_regulation of STAT3 1 0.16 0.91 0.03 35.84
123 INT271280 Stat1 Regulation of Mcl1 1 0.28 0.67 0 28.44
124 INT271282 Stat1 Regulation of Usp18 1 0.30 1.37 0 28.44
125 INT272016 Mtor Negative_regulation of INS 1 0.00 0.61 0 27.04
126 INT87024 Positive_regulation of ZAK Positive_regulation of Localization of IFNG 2 0.05 0.81 0.58 25.00
127 INT299303 SRC Regulation of Phosphorylation of VEGFA 1 0.12 0.05 0 24.00
128 INT232918 Binding of KRT2 and KRT8 1 0.17 0.59 0 21.88
129 INT299296 SRC Regulation of RPTOR 1 0.32 0 0 20.48
130 INT176326 IL2 Positive_regulation of Gene_expression of MUC1 1 0.08 0.71 0.04 19.72
131 INT299308 SRC Regulation of PI3 1 0.20 0 0 19.20
132 INT299294 SRC Regulation of VEGFA 1 0.20 0 0 18.80
133 INT255690 Binding of VEGFA and Flt1 8 0.34 3.44 0.61 17.92
134 INT351096 Binding of FKBP1A and MTOR 1 0.28 1.35 0 17.80
135 INT237924 PTPN1 Regulation of Gene_expression of CFLAR 1 0.01 0.7 0.19 14.36
136 INT351095 Binding of FKBP1A and RPS6KB1 1 0.24 0.36 0 11.64
137 INT351101 Negative_regulation of Binding of FKBP1A and RPS6KB1 1 0.27 0.36 0 11.64
138 INT299285 SRC Regulation of Gene_expression of QPCT 1 0.03 0 0 10.32
139 INT232914 Binding of KRT2 and KRT7 1 0.15 0.63 0.05 9.64
140 INT232907 Binding of KRT7 and KRT8 1 0.09 0.63 0.05 9.64
141 INT232917 Binding of KRT8 and KRT19 2 0.16 1.04 0.08 7.84
142 INT232916 Binding of KRT2 and KRT19 1 0.21 0.62 0.05 7.84
143 INT121651 Binding of CXCL12 and CXCR4 13 0.48 17.61 3.52 5.00
144 INT157767 Binding of TLR4 and LY96 8 0.54 4.05 1.95 5.00
145 INT213071 IL6 Positive_regulation of Gene_expression of CRP 4 0.52 6.58 1.68 5.00
146 INT299311 Binding of RPTOR and RICTOR 1 0.38 0.21 1.4 5.00
147 INT299281 Binding of RPTOR and MAPKAP1 1 0.23 0.21 1.3 5.00
148 INT260833 Binding of NRP2 and Flt1 1 0.00 3.61 1.22 5.00
149 INT330379 Gene_expression of IL10 Negative_regulation of Positive_regulation of MAPK14 1 0.00 1.95 1.18 5.00
150 INT207116 F2 Positive_regulation of F2r 5 0.12 2.16 1.16 5.00
151 INT173059 Binding of KDR and VEGFA 43 0.43 29.63 1.1 5.00
152 INT225158 Binding of CDK2 and CDKN1A 7 0.30 3.26 1.02 5.00
153 INT249347 Binding of FOS and JUN 4 0.19 6.15 0.89 5.00
154 INT260842 Binding of NRP2 and Kdr 1 0.00 2.28 0.85 5.00
155 INT306271 IL1A Positive_regulation of Gene_expression of IL6 1 0.30 0.85 0.8 5.00
156 INT306259 HDAC9 Negative_regulation of Gene_expression of TNF 1 0.21 0.89 0.78 5.00
157 INT196525 Binding of MMP2 and MMP9 2 0.32 2.49 0.78 5.00
158 INT306258 HDAC4 Negative_regulation of Gene_expression of TNF 1 0.09 0.89 0.78 5.00
159 INT172097 Binding of HLA-E and Trav6-3 10 0.02 3.71 0.71 5.00
160 INT306263 Binding of NFIB and TFAM 1 0.00 1.74 0.7 5.00
161 INT260832 Binding of NRP2 and Nrp1 1 0.00 2.32 0.7 5.00
162 INT306264 Binding of IL1A and MTX1 1 0.09 0.74 0.61 5.00
163 INT327334 Il10 Negative_regulation of TNF 1 0.02 1.46 0.6 5.00
164 INT327323 Il10 Positive_regulation of Gene_expression of Ttpa 1 0.02 1.43 0.58 5.00
165 INT327339 Gtf3a Positive_regulation of VEGFA 1 0.00 2.34 0.58 5.00
166 INT299263 PTPN3 Negative_regulation of VEGFA Positive_regulation of SRC 1 0.03 0.35 0.57 5.00
167 INT115146 MAPK1 Positive_regulation of EGR1 3 0.13 2.43 0.57 5.00
168 INT260821 NRP2 Positive_regulation of Gene_expression of TNF 1 0.01 1.48 0.56 5.00
169 INT260830 Binding of NRP2 and Flt1 Positive_regulation of Gene_expression of TNF 1 0.01 1.5 0.56 5.00
170 INT260845 Binding of Flt1 and Positive_regulation of Gene_expression of TNF 1 0.36 1.5 0.56 5.00
171 INT190702 CD40 Positive_regulation of Gene_expression of F3 1 0.00 1.4 0.55 5.00
172 INT339532 FGF2 Positive_regulation of YWHAZ 1 0.00 1.26 0.54 5.00
173 INT196522 Binding of MMP1 and TIMP1 1 0.39 0.29 0.53 5.00
174 INT196521 Binding of MMP2 and TIMP2 1 0.30 0.68 0.52 5.00
175 INT196527 Positive_regulation of Binding of MMP1 and MMP2 1 0.44 0.74 0.51 5.00
176 INT196524 Binding of MMP1 and MMP9 1 0.31 0.74 0.51 5.00
177 INT196519 Positive_regulation of Binding of MMP1 and MMP9 1 0.42 0.74 0.51 5.00
178 INT196520 Binding of MMP1 and MMP2 1 0.33 0.74 0.51 5.00
179 INT213809 F2 Positive_regulation of F2rl3 2 0.12 0.61 0.5 5.00
180 INT327332 VEGFA Positive_regulation of Gene_expression of Hgfac 1 0.00 2.02 0.49 5.00
181 INT321598 Binding of MLL and TNF 1 0.05 1.07 0.49 5.00
182 INT260836 Il18 Positive_regulation of Localization of VEGFA 1 0.06 1.67 0.48 5.00
183 INT327333 Binding of TNF and Fxr1 1 0.06 3.74 0.48 5.00
184 INT260843 Il6 Positive_regulation of Localization of VEGFA 1 0.06 1.67 0.47 5.00
185 INT260838 Il17a Positive_regulation of Localization of VEGFA 1 0.06 1.67 0.47 5.00
186 INT260839 Hivep3 Positive_regulation of Gene_expression of TNF 1 0.01 1.21 0.47 5.00
187 INT263917 Binding of SST and Sstr5 2 0.02 0.56 0.45 5.00
188 INT185381 TNF Regulation of TLR2 2 0.31 1.9 0.41 5.00
189 INT230724 EDN1 Positive_regulation of EDNRA 3 0.24 4.12 0.39 5.00
190 INT178217 IFNA1 Regulation of Cxcl10 1 0.01 0.86 0.37 5.00
191 INT262760 Binding of TEP1 and CD163L1 1 0.00 1.65 0.37 5.00
192 INT178218 IFNA1 Regulation of Tlr7 1 0.04 0.87 0.37 5.00
193 INT299288 AKT1 Positive_regulation of RPTOR 1 0.34 0.05 0.36 5.00
194 INT306254 Binding of TLR2 and LY96 1 0.25 1.29 0.36 5.00
195 INT287380 Binding of VEGFA and Kdr 12 0.18 11.97 0.34 5.00
196 INT327308 Binding of Elavl1 and Ttpa 1 0.02 1.73 0.34 5.00
197 INT330377 Positive_regulation of Binding of TLR2 and TLR9 1 0.09 2.79 0.32 5.00
198 INT330381 Binding of TLR2 and TLR9 1 0.07 2.77 0.32 5.00
199 INT330389 Positive_regulation of Binding of TLR2 and TLR8 1 0.08 2.78 0.32 5.00
200 INT72445 Binding of AGT and REN 3 0.34 0.88 0.31 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Renal Cancer. They are ordered first by their pain relevance and then by number of times they were reported in Renal Cancer. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT121493 Gene_expression of XRCC1 55 0.65 73.43 2.76 100.00
2 INT97973 Positive_regulation of XRCC1 24 0.40 30.95 2.26 100.00
3 INT74018 Binding of XRCC1 19 0.31 24.78 1.24 100.00
4 INT241104 Gene_expression of FH 7 0.66 20.35 0.31 100.00
5 INT100375 Gene_expression of Vhl 14 0.15 22.3 1.69 100.00
6 INT120519 Localization of XRCC1 15 0.78 17.03 1.51 100.00
7 INT74021 Regulation of XRCC1 15 0.44 16.91 0.88 100.00
8 INT74020 Negative_regulation of XRCC1 16 0.35 17.18 1.06 100.00
9 INT127654 Positive_regulation of Gene_expression of XRCC1 11 0.38 13.7 0.26 100.00
10 INT5116 Gene_expression of IL2 670 0.78 291.13 146.69 100.00
11 INT339092 Gene_expression of Rcc1 1 0.04 6.37 0 100.00
12 INT5058 Positive_regulation of IFNA1 356 0.70 245.75 60.52 100.00
13 INT7133 Negative_regulation of MME 85 0.59 29.22 33.1 100.00
14 INT121495 Transcription of XRCC1 7 0.49 6.11 0.09 100.00
15 INT263822 Positive_regulation of Gene_expression of LOX 8 0.50 11 1.06 100.00
16 INT210708 Regulation of Gene_expression of XRCC1 3 0.34 3.11 0 100.00
17 INT5841 Gene_expression of Vim 181 0.72 138.54 16.33 100.00
18 INT260340 Gene_expression of Rcc1 4 0.58 5.36 0.21 100.00
19 INT100376 Positive_regulation of Gene_expression of Vhl 4 0.10 6.47 1.47 100.00
20 INT132036 Negative_regulation of DPP4 126 0.59 63.24 9.51 100.00
21 INT241101 Negative_regulation of Gene_expression of FH 2 0.42 3.16 0 100.00
22 INT241114 Transcription of Vhl 1 0.11 2.3 0.05 100.00
23 INT312377 Transcription of DPP4 1 0.72 3.38 0.05 100.00
24 INT206929 Negative_regulation of Gene_expression of XRCC1 4 0.25 6.14 0.74 100.00
25 INT278063 Regulation of Positive_regulation of XRCC1 1 0.03 1.2 0.05 100.00
26 INT197135 Transcription of MME 4 0.69 3.23 0.13 100.00
27 INT251953 Positive_regulation of Transcription of XRCC1 1 0.29 1.07 0.04 100.00
28 INT260339 Positive_regulation of Gene_expression of Rcc1 1 0.11 2.28 0.15 100.00
29 INT199551 Regulation of Rcc1 2 0.01 2.63 0.05 100.00
30 INT241117 Regulation of Gene_expression of Vhl 1 0.06 2.5 0.07 100.00
31 INT260341 Positive_regulation of Rcc1 1 0.10 1.18 0.05 100.00
32 INT111986 Binding of IL24 2 0.34 0.83 0.09 100.00
33 INT111985 Binding of Il24 1 0.05 0.83 0.09 100.00
34 INT312376 Negative_regulation of Transcription of MME 1 0.43 1.65 0 100.00
35 INT339087 Binding of Ezh2 1 0.37 1.14 0 100.00
36 INT339093 Positive_regulation of Gene_expression of Rcc1 1 0.02 1.21 0 100.00
37 INT110579 Negative_regulation of Gene_expression of MME 15 0.58 12.8 1.81 100.00
38 INT278064 Positive_regulation of Localization of XRCC1 1 0.05 1.17 0.05 100.00
39 INT26434 Localization of MME 17 0.81 8.67 2.3 100.00
40 INT179036 Gene_expression of Fez1 1 0.70 13.28 0.11 100.00
41 INT123733 Gene_expression of Fhit 5 0.78 12.34 0.26 100.00
42 INT15511 Gene_expression of Tnfrsf1a 84 0.76 63.3 24.03 100.00
43 INT93361 Gene_expression of Trp53 208 0.78 175.35 16.65 100.00
44 INT98782 Gene_expression of Cdkn1b 70 0.75 36.43 1.9 100.00
45 INT339088 Negative_regulation of Gene_expression of Rcc1 1 0.02 1.37 0 100.00
46 INT77307 Gene_expression of Bcl2 399 0.77 319.77 38 100.00
47 INT193016 Regulation of EPAS1 9 0.15 7.38 0.06 100.00
48 INT322778 Localization of Rcc1 1 0.61 1.43 0 100.00
49 INT54565 Binding of SCLC1 12 0.31 20.41 0.81 100.00
50 INT61973 Positive_regulation of Gene_expression of TBP 2 0.49 1.5 0.18 100.00
51 INT329263 Localization of Prcc 1 0.11 0.9 0.07 100.00
52 INT152215 Binding of FH 10 0.41 14.13 0.19 99.98
53 INT83479 Gene_expression of KRT18 30 0.65 27.29 1 99.98
54 INT148121 Gene_expression of KRT8 35 0.65 29.07 1.05 99.98
55 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 99.98
56 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 99.98
57 INT48895 Gene_expression of Il10 333 0.78 221.2 138.52 99.98
58 INT48202 Gene_expression of Tgfb1 146 0.78 89.93 27.76 99.98
59 INT339094 Gene_expression of Ezh2 1 0.78 67.79 0.05 99.96
60 INT2843 Gene_expression of Epo 100 0.78 62.01 14.66 99.96
61 INT158755 Localization of XPA 1 0.39 2.73 0.26 99.96
62 INT18012 Gene_expression of EPO 169 0.78 108.36 13.75 99.96
63 INT122323 Positive_regulation of NOTCH1 36 0.70 35.63 3.7 99.96
64 INT654 Localization of REN 250 0.81 75.12 47.86 99.96
65 INT50010 Negative_regulation of CHR 5 0.42 3.64 1.41 99.96
66 INT57922 Gene_expression of CYP2C9 65 0.78 22.24 7.53 99.96
67 INT60695 Positive_regulation of Gene_expression of Il10 154 0.70 120.28 43.07 99.96
68 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65 99.92
69 INT68665 Binding of Vhl 9 0.48 10.3 0.82 99.92
70 INT200219 Positive_regulation of VHL 18 0.50 15.38 0.67 99.92
71 INT241099 Positive_regulation of Gene_expression of FH 3 0.43 5.17 0.11 99.92
72 INT74016 Binding of VHL 20 0.48 15.49 0.54 99.92
73 INT241113 Negative_regulation of Binding of Vhl 1 0.07 3.31 0.03 99.92
74 INT18522 Positive_regulation of Gene_expression of IFNA1 248 0.67 160.85 44.87 99.92
75 INT67039 Positive_regulation of Cpox 144 0.65 98.4 33.77 99.92
76 INT69993 Positive_regulation of Gene_expression of Cpox 93 0.55 69.4 22.05 99.92
77 INT15872 Positive_regulation of EPO 74 0.70 45.35 6.67 99.90
78 INT11775 Gene_expression of Ema 39 0.65 38.12 2.99 99.88
79 INT241118 Negative_regulation of Vhl 3 0.11 4.01 0.08 99.88
80 INT90673 Gene_expression of LOX 66 0.65 69.71 12.18 99.86
81 INT130057 Positive_regulation of CAV1 12 0.65 8.96 0.77 99.86
82 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 99.84
83 INT50670 Gene_expression of CPOX 763 0.76 442.13 195.02 99.84
84 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73 99.84
85 INT4877 Gene_expression of MME 184 0.78 122.82 24.78 99.84
86 INT84464 Gene_expression of DPP4 101 0.78 56.15 17.53 99.84
87 INT867 Gene_expression of IFNA1 930 0.78 594.85 168.03 99.84
88 INT48693 Regulation of VEGFA 268 0.62 191.88 31.52 99.84
89 INT50673 Positive_regulation of Gene_expression of CPOX 156 0.54 97.31 37.03 99.84
90 INT85829 Gene_expression of CA9 14 0.68 12.59 1.4 99.84
91 INT339095 Negative_regulation of Gene_expression of Ezh2 1 0.59 4.48 0 99.84
92 INT27268 Localization of Gtf3a 71 0.21 56.93 12.51 99.84
93 INT1759 Gene_expression of TIMP1 267 0.77 133.87 59.29 99.84
94 INT1758 Positive_regulation of Gene_expression of TIMP1 62 0.69 31.72 13.98 99.84
95 INT223599 Regulation of MTOR 14 0.42 8.52 0.49 99.84
96 INT150237 Localization of Ccr1 10 0.75 9.25 4.72 99.84
97 INT46619 Gene_expression of CSF1 80 0.73 36.63 12.94 99.84
98 INT138915 Gene_expression of Stat1 144 0.77 69.53 5.85 99.84
99 INT138917 Positive_regulation of Gene_expression of Stat1 63 0.69 36.76 1.71 99.84
100 INT174873 Regulation of Transcription of VEGFA 8 0.43 3.71 0.55 99.84
101 INT2673 Negative_regulation of PROC 93 0.57 50.34 12.79 99.84
102 INT69029 Gene_expression of PTPRC 127 0.75 74.26 11.57 99.84
103 INT294150 Regulation of Gene_expression of PTPRC 6 0.32 3.3 0.88 99.84
104 INT247569 Positive_regulation of Regulation of VEGFA 6 0.48 4.15 0.07 99.84
105 INT55737 Positive_regulation of MMP2 101 0.68 59.11 27.71 99.82
106 INT199793 Gene_expression of CYP2J2 18 0.68 19.6 0.67 99.82
107 INT86187 Positive_regulation of AKT1 199 0.69 122.13 19.44 99.80
108 INT268697 Positive_regulation of TCHP 1 0.07 1.86 0 99.80
109 INT42032 Localization of PNLIP 4 0.14 3.44 0.41 99.80
110 INT241100 Negative_regulation of Binding of FH 1 0.11 2.76 0.05 99.76
111 INT70613 Negative_regulation of Gene_expression of BCL2 48 0.59 38.91 5.22 99.76
112 INT60694 Gene_expression of Il10 567 0.78 369.48 143.69 99.76
113 INT278062 Negative_regulation of Vhl 2 0.33 2.72 0.04 99.72
114 INT85830 Positive_regulation of Gene_expression of CA9 4 0.41 5.47 1.02 99.72
115 INT266575 Negative_regulation of Gene_expression of CA9 1 0.37 0.69 0 99.72
116 INT111477 Gene_expression of KRT7 90 0.74 86.76 4.07 99.70
117 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 99.70
118 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 99.70
119 INT48891 Positive_regulation of Il10 143 0.70 101.42 56.72 99.70
120 INT48203 Positive_regulation of Tgfb1 67 0.70 41.31 11.07 99.70
121 INT10214 Gene_expression of VIM 153 0.78 115.88 16.29 99.68
122 INT14701 Negative_regulation of IFNA1 118 0.54 84.19 20.08 99.68
123 INT28083 Negative_regulation of Gene_expression of VIM 9 0.41 7.23 1.17 99.68
124 INT143443 Localization of HIF1A 14 0.78 10.93 1.49 99.68
125 INT161322 Localization of PTEN 9 0.73 5.65 0.57 99.68
126 INT213788 Gene_expression of Tfeb 18 0.66 7.9 2.07 99.64
127 INT213762 Gene_expression of Tfe3 1 0.47 1.34 0 99.64
128 INT9158 Gene_expression of Tnf 722 0.78 522.01 277.68 99.64
129 INT49995 Positive_regulation of Gene_expression of Tnf 187 0.70 125.07 70.54 99.64
130 INT101992 Localization of VEGFA 413 0.81 258.23 36.15 99.60
131 INT11159 Gene_expression of EGFR 698 0.78 548.93 25.69 99.60
132 INT74013 Binding of Met 1 0.06 2.01 0.09 99.60
133 INT268685 Negative_regulation of Phosphorylation of SLC25A5 1 0.31 1.28 0.05 99.60
134 INT268701 Negative_regulation of SLC25A5 2 0.31 2.61 0.08 99.60
135 INT268689 Negative_regulation of Gene_expression of SLC25A5 1 0.31 1.16 0.05 99.60
136 INT11158 Positive_regulation of Gene_expression of EGFR 165 0.70 131.26 4.93 99.60
137 INT28084 Positive_regulation of VIM 49 0.67 35.12 5.15 99.60
138 INT24672 Localization of FGF2 27 0.71 14.59 2.48 99.60
139 INT101517 Negative_regulation of PPARA 168 0.57 112.24 21.41 99.58
140 INT90674 Negative_regulation of LOX 56 0.57 38.01 8.58 99.56
141 INT65960 Gene_expression of BCL2 352 0.78 312.03 30.73 99.56
142 INT55736 Transcription of MMP2 11 0.68 5.78 2.28 99.56
143 INT302533 Gene_expression of Mest 2 0.65 1.86 0.05 99.56
144 INT6510 Gene_expression of AFP 130 0.78 119.2 9.19 99.54
145 INT95652 Gene_expression of Krt20 54 0.61 53.69 3.31 99.54
146 INT339091 Positive_regulation of Gene_expression of Ezh2 1 0.70 11.65 0 99.52
147 INT53475 Gene_expression of MRI1 116 0.59 77.68 33.98 99.52
148 INT328097 Positive_regulation of MBOAT7 1 0.02 3.57 0.38 99.52
149 INT48216 Gene_expression of Mak 2 0.58 1.89 0.34 99.52
150 INT48217 Gene_expression of SLC4A3 22 0.75 21.12 2.17 99.52
151 INT48219 Gene_expression of SLC4A1 34 0.75 33.18 2.84 99.52
152 INT48218 Gene_expression of KRIT1 16 0.75 7.59 1.8 99.52
153 INT201959 Positive_regulation of Gene_expression of DPP4 13 0.53 6.24 3.4 99.52
154 INT4879 Positive_regulation of Gene_expression of MME 17 0.69 12.48 2.46 99.52
155 INT6302 Binding of IFNA1 196 0.48 133.85 32.73 99.48
156 INT49439 Gene_expression of Cpox 508 0.73 326.97 130.17 99.48
157 INT60279 Gene_expression of VHL 70 0.78 75.21 2.21 99.44
158 INT58884 Gene_expression of SLC25A5 4 0.75 4.53 1.43 99.44
159 INT24080 Negative_regulation of Mtor 64 0.37 41.56 5.19 99.44
160 INT22383 Binding of IL2 59 0.48 39.06 8.56 99.42
161 INT5871 Binding of IFNA2 38 0.48 20.35 6.46 99.42
162 INT80124 Negative_regulation of VEGFA 450 0.58 311.19 44.53 99.40
163 INT241115 Regulation of Vhl 5 0.15 8.36 0.11 99.40
164 INT68681 Transcription of VEGFA 132 0.71 80.47 17.03 99.40
165 INT158754 Gene_expression of XPA 3 0.57 4.24 0.2 99.40
166 INT85084 Gene_expression of KRT19 66 0.73 42.56 1.82 99.38
167 INT99608 Transcription of MMP9 18 0.65 9.67 4.11 99.36
168 INT49750 Negative_regulation of CPOX 735 0.58 360.06 274.19 99.30
169 INT86024 Gene_expression of PPARA 736 0.78 497.93 91.14 99.28
170 INT6105 Positive_regulation of IL2 133 0.69 82.76 34.67 99.28
171 INT91891 Gene_expression of Kit 268 0.78 158.89 22.67 99.28
172 INT241116 Negative_regulation of Localization of Vhl 1 0.06 2.23 0 99.24
173 INT139331 Localization of Vhl 2 0.65 2.34 0.15 99.24
174 INT268705 Phosphorylation of SLC25A5 1 0.46 1.22 0.05 99.24
175 INT218956 Regulation of RNF123 3 0.01 1.06 0.03 99.22
176 INT141611 Positive_regulation of Gene_expression of Ccr1 25 0.69 20.32 6.42 99.20
177 INT279150 Gene_expression of RNF139 1 0.71 11.45 0 99.20
178 INT190023 Negative_regulation of Mrc1 15 0.25 12.36 0.16 99.20
179 INT170754 Localization of IFN1@ 121 0.78 66.78 15.6 99.18
180 INT53131 Transcription of TIMP1 8 0.68 3.89 1.5 99.18
181 INT86383 Negative_regulation of EGFR 258 0.59 173.94 13.32 99.16
182 INT350987 Positive_regulation of Positive_regulation of VHL 1 0.34 0.61 0 99.16
183 INT74017 Regulation of VHL 4 0.43 7.59 0.16 99.14
184 INT74019 Regulation of TSC1 27 0.35 23.61 0.79 99.14
185 INT11386 Positive_regulation of RAE1 3 0.11 1.53 0.83 99.12
186 INT61971 Gene_expression of TBP 9 0.65 5.14 0.8 99.12
187 INT173086 Negative_regulation of VHL 14 0.59 12.54 0.29 99.08
188 INT11062 Positive_regulation of MME 24 0.63 14.37 5.26 99.08
189 INT182319 Localization of Birc5 6 0.75 5.13 0.34 99.08
190 INT185370 Gene_expression of ANC 28 0.65 13.28 0.4 99.04
191 INT175653 Localization of PCAP 8 0.59 3.83 2.46 99.04
192 INT173089 Negative_regulation of VHLL 3 0.09 2.48 0.09 99.02
193 INT27243 Positive_regulation of SPINK1 13 0.68 26.71 2.92 99.00
194 INT110853 Negative_regulation of Pkia 1 0.14 1.19 0.08 99.00
195 INT4498 Gene_expression of F2 83 0.65 57.4 10.8 99.00
196 INT334415 Positive_regulation of Positive_regulation of SPINK1 1 0.53 3.83 0.04 99.00
197 INT94429 Transcription of TIMP2 3 0.61 4.05 0.67 98.96
198 INT131286 Binding of Egfr 26 0.44 13.58 0.78 98.96
199 INT235467 Negative_regulation of Gene_expression of VHL 9 0.43 8.67 0 98.96
200 INT17739 Gene_expression of S100B 226 0.78 132.7 26.4 98.92
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