D:Renal Disease

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pChart

Disease Term
Synonyms Diabetic Nephropathy, Diabetic Retinopathy Nephropathy, Disease Kidney, Diseases Kidney, DISORDER OF KIDNEY, Disorder Of Kidneys, Glomerulonephritis, Interstitial Nephritis, Kidney Disease, Kidney Diseases, Lupus Nephritis
Documents 4787
Hot Single Events 200
Hot Interactions 117

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Renal Disease. They are ordered first by their relevance to Renal Disease and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT251645 Binding of SERPING1 and CD79A 1 0.10 1.31 0.06 99.96
2 INT284392 Binding of ABCA1 and Vegfa 1 0.00 0.71 0 99.96
3 INT284393 Positive_regulation of Binding of ABCA1 and Vegfa 1 0.00 0.36 0 99.96
4 INT77753 Abnormal Regulation of CACNA1S 1 0.00 0.78 0.28 99.92
5 INT184542 Positive_regulation of Ccl2 Positive_regulation of Gpbar1 1 0.10 1.39 0.09 99.90
6 INT184541 Ccl2 Positive_regulation of Gpbar1 1 0.10 1.37 0.09 99.90
7 INT184539 Spp1 Positive_regulation of Gpbar1 1 0.03 1.37 0.09 99.90
8 INT184537 Ccl2 Positive_regulation of Spp1 1 0.34 1.37 0.09 99.82
9 INT184538 Positive_regulation of Ccl2 Positive_regulation of Spp1 1 0.34 1.38 0.09 99.82
10 INT313224 Negative_regulation of Binding of Cx3cr1 and Mcpt1 1 0.07 0.99 0.56 99.70
11 INT313223 Binding of Cx3cr1 and Mcpt1 1 0.06 0.99 0.56 99.44
12 INT88772 Negative_regulation of Binding of AGT and Agtrap 1 0.02 0.89 0.03 99.04
13 INT291622 HSD11B1 Regulation of CSTA 1 0.00 0.6 0.11 98.70
14 INT88773 Positive_regulation of Binding of AGT and Agtrap 1 0.01 0.88 0.05 98.64
15 INT88774 Binding of AGT and Agtrap 2 0.01 2.13 0.03 98.64
16 INT193693 Binding of Myd88 and Pain1 1 0.14 0.82 0.13 98.52
17 INT215978 Binding of HPT and Pth 1 0.01 0.92 0 97.92
18 INT330598 Binding of Il6 and Fig4 1 0.11 1.78 0.4 97.60
19 INT267116 Binding of Lmx1b and Nps 1 0.30 1.95 0 97.24
20 INT53951 Negative_regulation of Trib3 Negative_regulation of Gene_expression of Ptgs1 1 0.01 0.43 0.26 97.16
21 INT270732 DBP Negative_regulation of SHBG 1 0.00 1.08 0 96.76
22 INT165724 Bdkrb1 Positive_regulation of Adora1 1 0.24 1.65 0.43 96.60
23 INT178334 Binding of Pon1 and Chdh 1 0.11 11.45 0.66 96.56
24 INT344401 Agtr2 Positive_regulation of Gene_expression of Spp1 1 0.01 3.21 0 96.40
25 INT246938 Binding of Tlr4 and Tlr2 3 0.39 2.88 0.46 96.36
26 INT73775 Binding of GH1 and GHR 4 0.35 0.68 0.8 96.34
27 INT336132 Binding of AGTR1 and ANG 1 0.00 0.38 0.05 96.32
28 INT271450 Thy1 Regulation of TGFB1 1 0.00 0.62 0.25 96.08
29 INT306937 Tnfsf12 Positive_regulation of Gene_expression of Vcam1 1 0.05 1.79 0.27 95.56
30 INT84466 DPP4 Regulation of Localization of Naga 1 0.00 0.87 0.78 95.32
31 INT329839 Negative_regulation of Tnfsf13b Negative_regulation of Gene_expression of Ighm 1 0.05 2.28 0.06 95.20
32 INT306942 Tnfsf12 Positive_regulation of Gene_expression of ICAM1 1 0.04 1.78 0.27 95.08
33 INT230745 Negative_regulation of Ace Negative_regulation of Icam1 1 0.05 1.22 0.29 94.92
34 INT271445 Thy1 Regulation of Acta2 1 0.02 0.62 0.25 94.88
35 INT74027 Creb1 Regulation of Jun 4 0.27 1.04 1.02 94.84
36 INT171163 Creb1 Regulation of Sp1 1 0.03 0.62 0.1 94.84
37 INT306935 Tnfsf12 Positive_regulation of Gene_expression of Cxcl10 1 0.03 3.55 0.55 94.72
38 INT183750 Binding of EPO and TF 1 0.42 1.21 0 94.04
39 INT291377 Binding of CX3CR1 and Cx3cl1 2 0.36 3.57 1.02 93.72
40 INT306943 TF Positive_regulation of Gene_expression of Trf 1 0.01 0.9 0 93.68
41 INT196621 PTGER2 Negative_regulation of Gene_expression of DNAH8 1 0.00 0.33 0.28 93.68
42 INT191493 Binding of AGTR1 and NLRP3 2 0.03 2.35 0.39 93.40
43 INT182499 Binding of AGTR1 and AGTR2 3 0.20 2.79 0.28 93.40
44 INT271453 Thy1 Regulation of Thy1 Regulation of Col1a1 1 0.04 0.61 0.25 93.20
45 INT271446 Thy1 Regulation of Col1a1 1 0.05 0.61 0.25 93.20
46 INT254287 Binding of TNFSF13B and TNFRSF13B 1 0.01 1.33 0.3 93.12
47 INT254288 Binding of ZNF623 and TNFSF13B 1 0.00 1.33 0.3 93.12
48 INT233907 Positive_regulation of Binding of AGTR2 and NLRP3 1 0.01 1.09 0.08 93.12
49 INT165190 Binding of IL18 and LCN2 1 0.00 0.28 0 93.00
50 INT165188 Positive_regulation of Binding of IL18 and LCN2 1 0.00 0.28 0 93.00
51 INT263248 Binding of ADD1 and RAPGEF5 1 0.01 0.84 0 92.92
52 INT306941 Tnfsf12 Positive_regulation of Gene_expression of CCL2 1 0.03 1.65 0.27 92.92
53 INT233906 Binding of AGTR2 and NLRP3 1 0.01 1.09 0.08 92.80
54 INT165187 Positive_regulation of Binding of CST3 and IL18 1 0.03 0.28 0 92.76
55 INT165189 Binding of CST3 and IL18 1 0.02 0.28 0 92.76
56 INT263249 Binding of ADD1 and REN 1 0.03 0.82 0 91.84
57 INT236079 Binding of AGER and HLA-DQB1 1 0.25 1.06 0 91.84
58 INT236077 Binding of HLA-DQB1 and TNF 1 0.29 1.06 0 91.84
59 INT236076 Binding of HLA-DQB1 and LTA 1 0.25 1.06 0 91.84
60 INT238825 LTF Regulation of Localization of RBP4 1 0.05 1.08 0.16 91.52
61 INT165197 Positive_regulation of Binding of IL18 and Havcr1 1 0.00 0.28 0 90.92
62 INT165195 Binding of IL18 and Havcr1 1 0.00 0.28 0 90.92
63 INT165198 Positive_regulation of Binding of IL18 and Fabp1 1 0.01 0.55 0 90.60
64 INT165196 Binding of IL18 and Fabp1 1 0.01 0.55 0 90.60
65 INT333393 CFD Positive_regulation of Gene_expression of Timp1 1 0.07 0.82 0.16 90.24
66 INT225082 Binding of IGHG3 and fc 6 0.01 3.6 0.55 90.12
67 INT295616 ACACB Regulation of INS 1 0.02 0.6 0 89.92
68 INT270667 Binding of Bcat1 and Prh1 1 0.01 0.89 0.12 89.92
69 INT196631 PTGER2 Negative_regulation of NFKB1 1 0.00 0.32 0.28 89.68
70 INT246217 Cdkn1b Positive_regulation of VEGFA 1 0.03 1.13 0 89.56
71 INT246218 Fn1 Positive_regulation of VEGFA 1 0.03 1.13 0 89.56
72 INT317832 Binding of Mefv and Il1 1 0.03 3.89 0.7 88.84
73 INT317831 Binding of Mefv and Nlrx1 1 0.00 1.77 0.2 88.84
74 INT349653 Nfe2l2 Positive_regulation of Itk 1 0.00 0.79 0.22 87.52
75 INT344591 C1qa Positive_regulation of Gene_expression of IFN1@ 1 0.50 0.27 0.15 87.52
76 INT344402 Binding of Crp and Spp1 1 0.05 2.92 0.28 87.44
77 INT189488 Binding of Ccr1 and Ccl5 8 0.40 9.26 3.27 87.32
78 INT222185 Binding of Ccr1 and Ccl3 4 0.23 2.7 1.47 87.32
79 INT297307 Negative_regulation of Binding of Ccr1 and Ccl3 1 0.27 0.73 0.67 87.32
80 INT297313 Negative_regulation of Binding of Ccr1 and Ccl5 1 0.28 0.74 0.67 87.32
81 INT323675 Binding of THBD and BDNF-AS 1 0.02 2.45 0.04 87.08
82 INT323674 Binding of TFPI and THBD 1 0.02 2.45 0.04 87.08
83 INT299158 Binding of Lgals3 and Renbp 1 0.00 0.64 0.11 86.96
84 INT74014 Binding of TSC1 and XRCC1 1 0.02 1.98 0.09 86.92
85 INT74015 Binding of VHL and XRCC1 1 0.07 3.51 0.09 86.92
86 INT349652 Positive_regulation of Hmox1 Negative_regulation of Positive_regulation of Itk 1 0.01 0.85 0.25 86.80
87 INT126944 Binding of PKD2 and Pkd1 2 0.08 2.09 0.19 86.04
88 INT126943 Binding of Pkd1 and ZACN 1 0.00 0.69 0.14 86.04
89 INT291625 Binding of CSTA and RAPGEF5 1 0.03 4.81 0.37 85.76
90 INT126942 Binding of PKD2 and ZACN 1 0.00 1.38 0.28 85.68
91 INT214919 Pkd1 Positive_regulation of CDKN1A 1 0.51 2.6 0 85.12
92 INT335492 CREM Positive_regulation of Transcription of HMOX1 1 0.00 0.9 0.03 84.96
93 INT241853 Binding of SLC40A1 and HAMP 3 0.41 5.35 0.43 84.88
94 INT188692 Binding of Cd40 and Cd40lg 32 0.34 22.95 6.62 84.88
95 INT181583 Binding of Edn1 and Positive_regulation of NOS1 1 0.02 0.86 0.08 84.84
96 INT181584 Binding of EDNRB and Edn1 1 0.46 0.85 0.08 84.84
97 INT295617 UBXN11 Negative_regulation of SPTLC1 1 0.03 0.57 0 84.60
98 INT242400 Binding of Bdkrb2 and Ros1 1 0.02 0.84 0.15 84.56
99 INT247656 Binding of Tnnc1 and Gdf15 1 0.02 0.94 0.16 84.52
100 INT107028 KNG1 Regulation of Des 1 0.01 1.7 0.76 84.52
101 INT344590 Binding of IFN1@ and C3 1 0.32 0.3 0.16 83.60
102 INT302379 Crp Positive_regulation of Gene_expression of Ccl2 1 0.10 4.58 0.84 83.16
103 INT306925 IL36RN Positive_regulation of HAMP 1 0.01 1.39 0.1 83.12
104 INT279239 ELF3 Regulation of SH3GL3 1 0.11 0.44 0 83.12
105 INT271451 TGFB1 Regulation of Serpine1 1 0.00 0.68 0.18 83.04
106 INT230749 Crp Regulation of Agtr1a 1 0.07 1.33 0.19 82.24
107 INT215096 Binding of Hmgb1 and Tlr2 9 0.38 11.61 1.61 81.92
108 INT253585 Binding of IFN1@ and Csnk2a2 1 0.24 1.35 0.64 81.84
109 INT155484 Binding of CD86 and CTLA4 15 0.52 8.85 6.09 81.76
110 INT194538 Binding of PAEP and Negative_regulation of Uox 1 0.13 0.31 0 81.76
111 INT306924 IL6 Positive_regulation of HAMP 1 0.02 1.38 0.1 81.68
112 INT21649 ANG Regulation of Alb 1 0.04 0.64 0.07 81.52
113 INT308653 Proc Regulation of Gene_expression of Mapk8 1 0.00 1.48 0.36 80.60
114 INT231796 Binding of Fcr and Sle1 1 0.01 1.62 0.33 80.32
115 INT196629 PTGER2 Negative_regulation of Gene_expression of NA 1 0.00 0.24 0.22 80.24
116 INT177958 IGHE Positive_regulation of TNF 1 0.03 2.23 0 80.08
117 INT177959 Positive_regulation of IGHE Positive_regulation of TNF 1 0.03 2.23 0 80.08
118 INT182775 Binding of PTH and ROS1 1 0.04 1.73 0.04 79.56
119 INT306936 Binding of Tnfsf12 and Tnfrsf12a 1 0.05 4.84 0.45 79.36
120 INT181570 Binding of Edn1 and Mapk1 1 0.13 2.72 0.1 78.72
121 INT181571 Binding of Mapk8 and Mapk1 1 0.04 1.24 0.05 78.72
122 INT334893 ACE Negative_regulation of Gene_expression of AGT 1 0.03 1.41 0.1 78.48
123 INT181569 Binding of Edn1 and Mapk8 1 0.09 2.7 0.1 78.20
124 INT202310 Binding of PDGFB and Pdgfrb 1 0.11 0.39 0.04 77.80
125 INT330120 Bdkrb2 Regulation of Bdkrb1 1 0.19 1.26 0.38 77.72
126 INT291041 IL6 Regulation of IL36RN 1 0.00 1.09 0.17 76.08
127 INT82023 Binding of Ntrk1 and Ngf 5 0.53 3.48 3.92 75.00
128 INT288910 REN Regulation of Gene_expression of AGT 1 0.40 1.34 0 74.76
129 INT285568 Binding of TNF and Tnfsf10 1 0.12 1.39 0.36 74.64
130 INT332688 Ros1 Positive_regulation of Binding of Edn1 1 0.10 0.57 0.09 74.52
131 INT205159 SPP1 Positive_regulation of Gene_expression of TNFSF11 1 0.11 0.8 0 73.88
132 INT249665 Binding of GOPC and PSS 1 0.02 3.13 0.21 73.72
133 INT316375 Ang Positive_regulation of Nfkb1 1 0.08 0.73 0.23 73.60
134 INT205156 CD44 Positive_regulation of MMP9 1 0.51 0.24 0 72.96
135 INT181568 Positive_regulation of Mapk1 Positive_regulation of Gene_expression of Nos2 1 0.16 1.35 0.05 72.72
136 INT77083 Das Negative_regulation of Cyp2e1 1 0.20 0.59 1.06 72.72
137 INT246809 Negative_regulation of Tsc2 Positive_regulation of Positive_regulation of Ogg1 1 0.20 0.45 0 72.64
138 INT287145 Binding of PNN and Shbg 1 0.07 0.14 0.18 72.16
139 INT227398 Binding of H2afy and Alms1 1 0.01 1.42 0 72.12
140 INT227399 Binding of D5Mit424 and Alms1 1 0.01 0.71 0 72.12
141 INT269838 Binding of Hsp90b1 and Tlr2 1 0.26 1.75 0.03 71.56
142 INT149117 Binding of CD80 and CTLA4 31 0.52 12.7 7.73 70.72
143 INT203040 Binding of PDCD1 and PDCD1LG2 3 0.40 4.86 0.98 70.64
144 INT203056 Binding of Cd274 and PDCD1LG2 1 0.13 1.61 0.57 70.64
145 INT203041 Binding of CD274 and PDCD1LG2 1 0.03 1.61 0.57 70.64
146 INT203046 Binding of PDCD1 and CD274 2 0.40 3.97 0.68 70.64
147 INT203055 Binding of PDCD1 and Cd274 1 0.40 0.8 0.29 70.64
148 INT246784 Negative_regulation of Tsc2 Positive_regulation of Negative_regulation of Ogg1 1 0.20 0.43 0 70.64
149 INT252426 Binding of SLURP1 and Negative_regulation of Gene_expression of TNF 1 0.01 1.13 0.49 70.12
150 INT231769 TNF Negative_regulation of Gene_expression of HMOX1 1 0.26 4.75 1.15 70.08
151 INT193691 Positive_regulation of Positive_regulation of Bcr 1 0.01 0.07 0.08 69.84
152 INT165191 Fabp1 Positive_regulation of Havcr1 1 0.03 0.21 0 69.68
153 INT193692 IgG2a Positive_regulation of Bcr 1 0.02 0.07 0.08 69.28
154 INT193694 IgG2a Positive_regulation of Tlr9 1 0.05 0.07 0.08 69.28
155 INT283252 IRF6 Regulation of MIR155 1 0.01 1.04 0.03 69.04
156 INT283255 IRF6 Regulation of MIR15B 1 0.00 1.04 0.03 69.04
157 INT333396 CFD Positive_regulation of Bcl2l1 1 0.05 0.98 0.13 68.56
158 INT231797 Glrb Regulation of Negative_regulation of TNF 1 0.02 1.49 0.25 68.20
159 INT283260 TNF Positive_regulation of TNF Regulation of MIR15B 1 0.01 1.03 0.03 67.68
160 INT283253 TNF Regulation of MIR15B 1 0.01 1.03 0.03 67.68
161 INT283257 TNF Regulation of MIR155 1 0.04 1.03 0.03 67.68
162 INT291621 RAPGEF5 Regulation of CSTA 1 0.04 0.43 0.03 66.56
163 INT241772 AVP Positive_regulation of ADCY1 1 0.09 1.08 0.15 66.20
164 INT349219 PTPRC Positive_regulation of Gene_expression of SLC3A2 1 0.11 0.53 0 66.00
165 INT254286 Binding of TNFSF13B and TNFRSF13C 1 0.07 1.26 0.08 66.00
166 INT111221 MMEL1 Negative_regulation of HMOX1 1 0.01 1 1.16 65.88
167 INT331627 Binding of HLA-DRB3 and Pain1 1 0.00 2.15 0.14 65.76
168 INT337572 TREM1 Regulation of CRP 1 0.05 0.99 0.07 65.20
169 INT294708 CRP Positive_regulation of Gene_expression of VCAM1 2 0.31 1.92 0.56 65.12
170 INT316371 Ang Negative_regulation of Ren1 1 0.16 0.64 0.05 65.12
171 INT331628 Binding of HLA-DQA2 and Pain1 1 0.01 2.13 0.14 64.48
172 INT213390 Positive_regulation of Binding of CHKB and SELPLG 1 0.01 0.46 0 64.40
173 INT213393 Binding of CHKB and SELPLG 1 0.01 0.46 0 64.40
174 INT213391 Positive_regulation of Binding of CHKB and XPO1 1 0.04 0.46 0 64.08
175 INT213394 Binding of CHKB and XPO1 1 0.03 0.46 0 64.08
176 INT316376 Binding of Ang and Atp6ap2 1 0.06 0.87 0.16 63.80
177 INT299783 Binding of Cd28 and Cd80 7 0.14 6.49 2.49 63.44
178 INT101942 Binding of CD40 and CD40LG 16 0.23 15.24 4.01 63.20
179 INT214902 Binding of Pcna and Trib3 1 0.00 1.51 0 63.08
180 INT140813 Binding of Retn and Adipoq 1 0.03 1.18 0.06 63.04
181 INT233304 Binding of SRY and SLC22A8 1 0.34 0.93 0 62.96
182 INT336134 Binding of EXTL3 and ATP6AP2 1 0.00 0.37 0 62.88
183 INT336129 Binding of ANG and EXTL3 1 0.01 0.38 0 62.88
184 INT336133 Binding of EXTL3 and REN 1 0.03 0.37 0 62.88
185 INT242858 Binding of HFE and INS 1 0.06 1.64 0 62.64
186 INT336131 Binding of ANG and ATP6AP2 1 0.00 0.38 0 62.00
187 INT354889 Binding of TNF and Gtf3a 1 0.00 2.05 0 61.96
188 INT331155 Akt1 Positive_regulation of Binding of Bad 1 0.04 0.93 0.04 61.84
189 INT354890 Binding of TNF and Tnfsf13b 1 0.01 2.05 0 61.64
190 INT354887 Binding of Tnfsf13b and Gtf3a 1 0.01 2.05 0 61.64
191 INT336130 Binding of ANG and REN 1 0.06 0.38 0 61.28
192 INT331153 Akt1 Positive_regulation of Bad 1 0.03 0.92 0.04 61.20
193 INT220905 Cfb Positive_regulation of C3 1 0.06 0.91 0.11 60.84
194 INT276586 Binding of Wt1 and Actn1 1 0.34 0.41 0 60.72
195 INT276591 Binding of Actn1 and KTWS 1 0.02 0.41 0 60.72
196 INT236078 Binding of AGER and HLA-DMA 1 0.08 0.81 0 60.08
197 INT331156 Akt1 Positive_regulation of Phosphorylation of Bad 1 0.02 0.91 0.04 59.84
198 INT172838 Binding of ISL1 and T2dm2 1 0.00 2.41 0 59.84
199 INT270661 Regulation of Wnk1 Regulation of Napg 1 0.04 1.13 0.04 59.76
200 INT270659 Wnk1 Regulation of Napg 1 0.04 1.12 0.04 59.76

Single Events

The table below shows the top 200 pain related interactions that have been reported for Renal Disease. They are ordered first by their pain relevance and then by number of times they were reported in Renal Disease. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT4679 Negative_regulation of RAPGEF5 55 0.57 47.51 4.55 100.00
2 INT110427 Gene_expression of Spp1 199 0.78 176.11 23.31 100.00
3 INT142593 Positive_regulation of Tlr2 85 0.70 75.9 13.62 100.00
4 INT306931 Binding of Tnfsf12 1 0.19 7.53 0.35 100.00
5 INT42994 Binding of BDNF-AS 21 0.35 14.17 4 100.00
6 INT9429 Positive_regulation of Clcn1 18 0.58 10.03 2.07 100.00
7 INT177434 Gene_expression of IGAN 4 0.42 2.52 0.22 100.00
8 INT43907 Binding of CD79A 28 0.48 28.11 3.04 100.00
9 INT36064 Binding of CST3 14 0.47 16.38 1.12 100.00
10 INT2120 Gene_expression of CD79A 159 0.78 111.69 17.16 100.00
11 INT724 Negative_regulation of Alb 151 0.59 93.57 29.65 100.00
12 INT152808 Positive_regulation of Rcn1 1 0.52 1.19 1.08 100.00
13 INT279951 Negative_regulation of Negative_regulation of RAPGEF5 1 0.18 2.57 0 100.00
14 INT79928 Positive_regulation of Localization of ALB 10 0.60 8.96 1.05 100.00
15 INT81293 Positive_regulation of Gene_expression of Hmox1 53 0.70 41.54 7.25 100.00
16 INT17381 Gene_expression of Tbxa2r 146 0.78 65.01 34.15 100.00
17 INT16408 Negative_regulation of Nppb 14 0.53 5.49 3.74 100.00
18 INT45159 Regulation of Nppb 16 0.54 13.57 4.46 100.00
19 INT349045 Gene_expression of ANXA7 1 0.03 1.22 0.03 100.00
20 INT9884 Localization of CD79A 41 0.78 21.75 3.06 100.00
21 INT142873 Positive_regulation of IGAN 2 0.50 1.19 0.27 100.00
22 INT16234 Positive_regulation of CFH 25 0.50 26.05 3.33 100.00
23 INT40053 Positive_regulation of Positive_regulation of Ren1 4 0.54 4.41 0.81 100.00
24 INT314777 Negative_regulation of Gene_expression of CST3 1 0.41 1.32 0 100.00
25 INT262262 Negative_regulation of LRSAM1 2 0.03 1.34 0 100.00
26 INT9239 Regulation of Gene_expression of IL6 106 0.61 75.24 36.53 100.00
27 INT86411 Negative_regulation of Negative_regulation of TNF 24 0.42 17.6 7.89 100.00
28 INT19188 Binding of Igh-6 11 0.48 2.97 4.88 100.00
29 INT45503 Binding of EPO 42 0.48 24.85 2.88 100.00
30 INT170853 Positive_regulation of Gene_expression of CFD 7 0.23 9.89 1.41 100.00
31 INT297322 Binding of Apoa2 3 0.36 1.7 0.27 100.00
32 INT226195 Regulation of Gene_expression of Mstn 2 0.48 1.23 0.2 100.00
33 INT276549 Binding of Actn4 1 0.32 0.61 0 100.00
34 INT309803 Negative_regulation of Binding of Apoa2 1 0.41 1.02 0 100.00
35 INT309802 Positive_regulation of Binding of Apoa2 1 0.49 1.03 0 100.00
36 INT276542 Binding of Myh9 1 0.40 0.61 0 100.00
37 INT16997 Binding of PRTN3 34 0.48 33.44 6.45 99.98
38 INT15872 Positive_regulation of EPO 74 0.70 45.35 6.67 99.98
39 INT20664 Binding of ACE 60 0.48 35.27 9.16 99.98
40 INT25958 Regulation of Ace 26 0.59 11.88 7.87 99.98
41 INT121338 Binding of MTUS1 5 0.07 3.41 0.16 99.98
42 INT122902 Positive_regulation of Gene_expression of Spp1 54 0.70 56.3 6.33 99.96
43 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 99.96
44 INT66280 Gene_expression of Nos2 534 0.78 330.78 157.07 99.96
45 INT81498 Positive_regulation of Gene_expression of CCL2 107 0.70 53.89 45.22 99.96
46 INT28088 Binding of Alb 34 0.47 11.06 5.48 99.96
47 INT86183 Binding of Igha 2 0.47 1.5 0.27 99.96
48 INT28872 Positive_regulation of CSRP1 49 0.70 47.23 11.7 99.96
49 INT375 Positive_regulation of REN 293 0.70 152.46 47.55 99.92
50 INT660 Negative_regulation of REN 194 0.59 82.06 29.46 99.92
51 INT1734 Negative_regulation of HSD11B1 116 0.57 125.13 10.52 99.92
52 INT37734 Positive_regulation of Ang 18 0.46 9.17 2.87 99.92
53 INT61117 Gene_expression of Ppara 158 0.68 69.3 15.98 99.92
54 INT139263 Gene_expression of Mstn 10 0.62 6.67 1.51 99.92
55 INT25634 Binding of Mpo 21 0.48 14.78 4.39 99.92
56 INT22502 Gene_expression of Hal 21 0.53 9.8 3.32 99.92
57 INT322712 Negative_regulation of Binding of Ccl2 4 0.32 1.29 1.44 99.92
58 INT96860 Positive_regulation of Binding of Ang 3 0.33 1.4 0.21 99.92
59 INT84646 Binding of PDHA1 2 0.32 1.36 0.8 99.90
60 INT11118 Gene_expression of RAPGEF5 13 0.65 9.35 0.43 99.88
61 INT164479 Positive_regulation of Gene_expression of RAPGEF5 2 0.49 1.3 0.08 99.88
62 INT112016 Negative_regulation of IgG2a 9 0.32 4.62 1.28 99.88
63 INT136271 Gene_expression of PNN 9 0.63 5.44 1 99.88
64 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98 99.86
65 INT158083 Gene_expression of FGD1 24 0.67 6.82 2.83 99.86
66 INT122323 Positive_regulation of NOTCH1 36 0.70 35.63 3.7 99.86
67 INT146758 Gene_expression of LCN2 45 0.78 38.29 2.97 99.84
68 INT24326 Gene_expression of Ngf 346 0.78 218.67 184.71 99.84
69 INT2391 Negative_regulation of PTGS1 501 0.59 207.62 205.6 99.84
70 INT7475 Positive_regulation of Hdl1 138 0.67 175.81 15.05 99.84
71 INT615 Regulation of Alb 66 0.62 33.43 15.33 99.84
72 INT309692 Gene_expression of MIR638 1 0.07 2.17 0 99.84
73 INT309695 Gene_expression of MIR663A 1 0.58 2.14 0 99.84
74 INT309693 Gene_expression of MIR371A 1 0.58 2.05 0 99.84
75 INT309696 Gene_expression of MIR423 1 0.58 2.11 0 99.84
76 INT58288 Positive_regulation of Gene_expression of Crp 83 0.61 82.23 23.7 99.84
77 INT178198 Gene_expression of C3 62 0.78 39.5 7.69 99.84
78 INT11859 Positive_regulation of Tbxa2r 44 0.61 22.62 9.61 99.84
79 INT105248 Negative_regulation of Vegfa 8 0.47 6.19 1.61 99.84
80 INT5207 Negative_regulation of Alms1 70 0.41 41.56 13.68 99.84
81 INT7678 Localization of Alb 142 0.81 80.93 22.49 99.80
82 INT122812 Gene_expression of SNRNP70 130 0.75 67 12.5 99.80
83 INT156130 Binding of SERPING1 29 0.42 26.16 2.52 99.80
84 INT711 Positive_regulation of PIK3C2A 83 0.70 76.87 13.18 99.80
85 INT282633 Gene_expression of UGT2B17 2 0.67 0.39 0 99.80
86 INT176519 Regulation of Gene_expression of Spp1 7 0.58 8.54 0.35 99.80
87 INT170854 Gene_expression of CFD 26 0.68 39.77 4.74 99.80
88 INT192673 Gene_expression of Hdac5 6 0.61 2.84 1.51 99.80
89 INT192675 Positive_regulation of Gene_expression of Hdac5 2 0.33 2.52 1.13 99.80
90 INT40844 Localization of Naga 2 0.53 2.88 3.42 99.78
91 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 99.76
92 INT55879 Gene_expression of CCL2 421 0.78 240.74 166.02 99.76
93 INT273675 Binding of ACACB 7 0.42 8.69 0.09 99.76
94 INT169180 Binding of SNRNP70 204 0.47 119.1 29.3 99.76
95 INT276523 Negative_regulation of Gene_expression of Flna 2 0.48 0.8 0 99.76
96 INT84595 Negative_regulation of Aqp2 11 0.58 4.88 1.78 99.76
97 INT27574 Binding of ZFPL1 1 0.07 1.01 0.31 99.76
98 INT113371 Binding of Neil1 1 0.29 1.34 0.18 99.76
99 INT5759 Positive_regulation of Ptgs1 127 0.69 53.45 53.04 99.74
100 INT306930 Gene_expression of Tnfsf12 1 0.31 21.25 1.65 99.72
101 INT146759 Positive_regulation of LCN2 18 0.69 18.44 1.08 99.72
102 INT146757 Positive_regulation of Gene_expression of LCN2 5 0.69 7.21 0.72 99.72
103 INT65642 Binding of Dync1h1 27 0.41 15.83 2.68 99.72
104 INT184280 Positive_regulation of AGER 8 0.52 9.05 2.43 99.72
105 INT82878 Gene_expression of Ccl2 201 0.78 164.95 101.35 99.72
106 INT7675 Gene_expression of ENG 146 0.77 45.35 34.6 99.72
107 INT20006 Gene_expression of MT1F 27 0.68 19.55 3.18 99.72
108 INT106760 Positive_regulation of Dusp1 16 0.59 8.5 3.35 99.72
109 INT1038 Negative_regulation of F2 26 0.58 15.12 6.75 99.72
110 INT703 Positive_regulation of Pth 177 0.70 127.09 27.26 99.68
111 INT573 Negative_regulation of C3 60 0.59 41.37 7.78 99.68
112 INT349145 Negative_regulation of Negative_regulation of Hspb1 1 0.37 1.47 0 99.68
113 INT82894 Positive_regulation of Fcer2 4 0.05 1.27 0.14 99.68
114 INT27670 Negative_regulation of Ace 122 0.57 79.21 18.08 99.66
115 INT654 Localization of REN 250 0.81 75.12 47.86 99.66
116 INT18773 Localization of ALB 117 0.80 69.18 13.8 99.64
117 INT15516 Gene_expression of Crp 711 0.77 615.33 173.09 99.64
118 INT138785 Gene_expression of Lcn2 9 0.56 9.88 2.41 99.64
119 INT100384 Regulation of SNRNP70 24 0.60 11 3.56 99.64
120 INT349041 Binding of Cnn3 1 0.23 0.19 0 99.64
121 INT122041 Binding of Ppara 308 0.48 189.17 51.48 99.62
122 INT150476 Positive_regulation of ELF3 32 0.56 13.61 2.39 99.60
123 INT67981 Positive_regulation of CCL2 165 0.70 136.84 61.85 99.58
124 INT756 Gene_expression of C3 138 0.75 100.6 19.2 99.58
125 INT3952 Negative_regulation of ALB 116 0.59 72.18 18.35 99.58
126 INT82883 Positive_regulation of Ccl2 105 0.69 84.96 42.27 99.58
127 INT117518 Transcription of Ccl2 12 0.68 11.12 3.61 99.58
128 INT117519 Positive_regulation of Transcription of Ccl2 5 0.49 6.01 2.54 99.58
129 INT96861 Binding of Ang 11 0.32 4.46 1.1 99.58
130 INT246761 Positive_regulation of Gene_expression of Tsc2 2 0.41 1.17 0 99.58
131 INT1123 Positive_regulation of CD79A 74 0.70 51.96 7.14 99.56
132 INT169475 Localization of HRAS 14 0.73 9.02 3.9 99.56
133 INT96850 Negative_regulation of CCL2 42 0.59 24.89 12.55 99.54
134 INT9084 Positive_regulation of Nppb 74 0.70 69.77 11.85 99.52
135 INT1179 Negative_regulation of Ace 157 0.59 67.03 30.46 99.52
136 INT37193 Negative_regulation of BDNF-AS 21 0.37 15.06 3.12 99.52
137 INT17028 Positive_regulation of Scn7a 35 0.41 9.83 7.44 99.52
138 INT19993 Negative_regulation of Ren1 43 0.58 20.89 5.04 99.50
139 INT9083 Gene_expression of Nppb 74 0.78 70.96 12.19 99.50
140 INT5408 Localization of Alb 30 0.73 12.1 3.84 99.50
141 INT119227 Gene_expression of Tsc2 8 0.68 10.67 0.03 99.50
142 INT7205 Positive_regulation of HBG1 65 0.69 40.35 6.37 99.48
143 INT19023 Localization of B2m 6 0.75 5.15 0.46 99.48
144 INT12324 Positive_regulation of PRTN3 26 0.70 18.82 4.55 99.48
145 INT21609 Positive_regulation of RASGRP1 58 0.50 40.78 5.47 99.48
146 INT242865 Binding of HFE 7 0.42 6.01 0.12 99.48
147 INT188774 Binding of RAPGEF5 12 0.29 13.55 1.04 99.46
148 INT172328 Negative_regulation of Phl1 1 0.03 61.51 0.97 99.46
149 INT11679 Negative_regulation of F13A1 55 0.54 33.69 9.43 99.46
150 INT172323 Gene_expression of Phl1 1 0.03 14 0.16 99.46
151 INT10586 Localization of B2M 15 0.68 8.67 3.46 99.44
152 INT41549 Positive_regulation of Localization of B2M 5 0.59 4.26 2.42 99.44
153 INT899 Gene_expression of F13A1 122 0.70 78.02 16.26 99.44
154 INT545 Binding of GC 15 0.45 10.74 3.47 99.44
155 INT147518 Regulation of Gene_expression of Ppara 7 0.42 4.59 0.97 99.44
156 INT934 Regulation of Gtf3a 25 0.35 11.35 6.34 99.44
157 INT154455 Gene_expression of dds 4 0.58 3.84 0.46 99.44
158 INT276544 Gene_expression of Flna 3 0.63 1.97 0 99.42
159 INT279246 Positive_regulation of Gene_expression of SH3GL3 1 0.12 0.59 0 99.42
160 INT106200 Binding of Ccl2 22 0.42 16.7 9.75 99.42
161 INT8112 Regulation of EPO 38 0.58 22.04 2.76 99.40
162 INT127363 Binding of Cpb1 8 0.32 2.5 1.14 99.38
163 INT88133 Positive_regulation of Spp1 8 0.66 10.07 1.33 99.38
164 INT121141 Transcription of Spp1 6 0.34 5.02 0.38 99.38
165 INT1724 Negative_regulation of ACE 437 0.59 315.64 74.48 99.36
166 INT142594 Gene_expression of Tlr2 165 0.78 139.73 22.26 99.36
167 INT77538 Gene_expression of Cnn3 2 0.55 10.24 1.55 99.36
168 INT122901 Positive_regulation of Spp1 67 0.67 58.03 7.49 99.36
169 INT39712 Binding of pad 82 0.48 110.92 10.33 99.36
170 INT5793 Binding of CTS 110 0.48 63.91 40.62 99.36
171 INT120811 Gene_expression of Gopc 1174 0.59 428.49 150.55 99.36
172 INT170051 Positive_regulation of Gene_expression of Gopc 150 0.43 56.75 16.93 99.36
173 INT109415 Negative_regulation of Positive_regulation of RASGRP1 5 0.34 2.16 0.22 99.34
174 INT17618 Gene_expression of B2M 36 0.66 16.39 6.68 99.28
175 INT91703 Negative_regulation of Myoz1 78 0.58 53.78 13.5 99.28
176 INT100861 Binding of CRP 179 0.48 175.2 26.45 99.28
177 INT4680 Positive_regulation of Negative_regulation of RAPGEF5 2 0.45 1.66 0.07 99.28
178 INT121985 Positive_regulation of SLEB1 10 0.29 10.52 0.64 99.28
179 INT150875 Negative_regulation of Localization of Alb 3 0.35 2.72 0.51 99.28
180 INT114220 Negative_regulation of Gene_expression of Cdkn1b 4 0.33 4.11 1.23 99.28
181 INT161749 Regulation of VUR 9 0.39 9.3 0.46 99.28
182 INT44873 Negative_regulation of LCAT 16 0.59 6.92 3.13 99.26
183 INT170335 Gene_expression of INCENP 176 0.54 91.62 15.31 99.26
184 INT142596 Positive_regulation of Gene_expression of Tlr2 42 0.69 38.41 6.67 99.24
185 INT16236 Negative_regulation of CFH 31 0.57 19.59 3.36 99.24
186 INT15723 Gene_expression of Fn1 47 0.78 37.59 8.51 99.22
187 INT169697 Negative_regulation of Ephx2 35 0.59 38.21 5.92 99.22
188 INT91544 Gene_expression of CHI3L1 60 0.75 77.72 13.9 99.22
189 INT125885 Positive_regulation of Gene_expression of CHI3L1 8 0.49 10.8 2.64 99.22
190 INT613 Gene_expression of Alb 268 0.78 149.84 42.78 99.20
191 INT210057 Gene_expression of SH3GL3 24 0.50 8.69 0.94 99.20
192 INT3550 Negative_regulation of GLA 52 0.59 33.93 5.26 99.20
193 INT52611 Negative_regulation of Ptgs2 142 0.59 66.31 52.71 99.20
194 INT699 Positive_regulation of A2M 16 0.66 10.49 2.5 99.20
195 INT17489 Regulation of F13A1 28 0.45 15.79 4.93 99.20
196 INT281429 Regulation of Gene_expression of FTL 1 0.22 1.27 0.15 99.20
197 INT16996 Gene_expression of PRTN3 113 0.75 85.61 22.57 99.18
198 INT47734 Positive_regulation of RAPGEF5 19 0.56 13.16 1.41 99.16
199 INT15515 Positive_regulation of Crp 700 0.70 604.24 150.15 99.16
200 INT20622 Gene_expression of LDHA 107 0.76 77.97 16.3 99.16
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