D:Renal Failure

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pChart

Disease Term
Synonyms Capd, Continuous Ambulatory Peritoneal Dialysis, Failure Kidney, Failure Renal, Failures Kidney, Failures Renal, Kidney Failure, Kidney Failures, Peritoneal Dialysis, Renal Dialysis, Renal Failures
Documents 4049
Hot Single Events 200
Hot Interactions 20

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Renal Failure. They are ordered first by their relevance to Renal Failure and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT251645 Binding of SERPING1 and CD79A 1 0.10 1.31 0.06 97.08
2 INT210597 Negative_regulation of Binding of TNFSF11 and TNFRSF11A 3 0.26 5.66 0.33 96.72
3 INT182636 Binding of TNFSF11 and TNFRSF11A 16 0.29 17.5 0.84 96.08
4 INT298733 INS Regulation of ACSBG1 1 0.00 0.97 0.05 93.08
5 INT298734 USE1 Regulation of ACSBG1 1 0.00 0.97 0.05 93.08
6 INT325489 Agtr2 Positive_regulation of Ephx2 1 0.04 0.51 0.08 91.28
7 INT307075 Tbxas1 Negative_regulation of Negative_regulation of PLG 1 0.01 1.22 0.11 90.24
8 INT155839 Binding of GGT1 and Shbg 1 0.07 1.21 0.12 89.40
9 INT19535 Binding of ADRA1D and ALB 3 0.42 0.8 1.15 88.32
10 INT317602 Binding of TNC and PAH 1 0.02 1.74 0 85.92
11 INT16891 GHRH Regulation of GH1 5 0.37 1.94 1.82 85.20
12 INT215978 Binding of HPT and Pth 1 0.01 0.92 0 84.12
13 INT296893 Nps Negative_regulation of Gene_expression of REN 1 0.00 1.05 0.04 82.96
14 INT224423 Binding of TNFRSF11B and TNFRSF11A 3 0.19 2.36 0.37 82.76
15 INT209881 Binding of TNFRSF11B and TNFSF11 8 0.36 8.92 0.86 82.04
16 INT55809 Binding of Ttr and Fap 1 0.12 2.56 0.19 82.00
17 INT184543 Agt Positive_regulation of Ccl2 1 0.16 3.18 0.43 81.84
18 INT92247 Binding of F13a1 and Fgg 1 0.00 0.68 0.14 81.52
19 INT328380 AR Negative_regulation of Gene_expression of Ghrl 1 0.01 0.55 0.07 80.64
20 INT220117 Il6 Positive_regulation of TNF 1 0.01 2.45 0.63 80.40
21 INT276590 Binding of Wt1 and KTWS 1 0.02 0.3 0 78.36
22 INT92246 Binding of Hgfac and F13a1 1 0.00 0.65 0.13 76.76
23 INT177714 Binding of GALNT3 and REN 1 0.01 2.36 0.12 76.36
24 INT328299 Binding of GHRH and GHS 1 0.07 2.21 0.31 75.32
25 INT301178 UCP2 Negative_regulation of ROS1 1 0.29 1.41 0 74.40
26 INT210596 TNFRSF11B Negative_regulation of Binding of TNFSF11 2 0.11 1.62 0.04 73.88
27 INT210593 TNFRSF11B Negative_regulation of Binding of TNFSF11 and TNFRSF11A 2 0.10 1.62 0.04 73.88
28 INT254232 Binding of Tlr4 and TRAM1 2 0.07 1.11 0 73.24
29 INT207783 Binding of MRC1 and Ap3d1 1 0.00 2.54 0.22 72.92
30 INT355504 ANGPT2 Positive_regulation of CYBB 1 0.01 0.81 0.18 72.40
31 INT173059 Binding of KDR and VEGFA 43 0.43 29.63 1.1 69.12
32 INT210990 Binding of KCNMA1 and PKDREJ 1 0.00 0.6 0.19 66.24
33 INT294091 Binding of PGF and VEGFA 1 0.02 1.21 0 65.60
34 INT239355 Binding of Nr1h2 and Positive_regulation of Gene_expression of CETP 1 0.17 3.75 0.14 64.80
35 INT225082 Binding of IGHG3 and fc 6 0.01 3.6 0.55 64.56
36 INT239323 Binding of Nr1h2 and Positive_regulation of Positive_regulation of Tgfb1 1 0.00 3.71 0.14 63.92
37 INT171162 Negative_regulation of Ace Negative_regulation of Gene_expression of Ccl2 1 0.02 1.18 0.1 63.72
38 INT271348 Binding of CHKB and MB 1 0.01 1.01 0 62.44
39 INT294095 Binding of TXK and Gtf3a 1 0.00 2.33 0 61.80
40 INT155484 Binding of CD86 and CTLA4 15 0.52 8.85 6.09 61.28
41 INT149117 Binding of CD80 and CTLA4 31 0.52 12.7 7.73 60.56
42 INT207255 INS Negative_regulation of Gene_expression of NCKIPSD 1 0.02 0.94 0 60.56
43 INT207261 ZNF236 Positive_regulation of Gene_expression of NCKIPSD 1 0.00 0.93 0 60.56
44 INT344402 Binding of Crp and Spp1 1 0.05 2.92 0.28 60.20
45 INT207260 INS Negative_regulation of Gene_expression of TXNIP 1 0.39 1.71 0 59.72
46 INT207265 ZNF236 Positive_regulation of Gene_expression of TXNIP 1 0.04 1.6 0 59.72
47 INT329479 Binding of TNFRSF11B and TNF 1 0.04 0.71 0 59.20
48 INT329480 Binding of TNFRSF11B and TNFSF10 1 0.03 0.71 0 59.20
49 INT49283 Binding of IGLL1 and IFNK 1 0.02 0.9 0.1 58.08
50 INT274387 Binding of POLA1 and IGSF9 1 0.01 0.58 0 57.44
51 INT239327 Positive_regulation of Binding of Lcat and Hdl1 1 0.06 1.52 0.06 56.08
52 INT239326 Binding of Lcat and Hdl1 1 0.05 1.52 0.06 56.08
53 INT210993 Binding of SEA and PKDREJ 1 0.05 0.17 0.1 55.56
54 INT210988 Binding of SP3 and PKDREJ 1 0.01 0.17 0.1 55.56
55 INT210991 Binding of FSCN1 and PKDREJ 1 0.00 0.17 0.1 55.56
56 INT210992 Binding of KCNMA1 and SP3 1 0.00 0.17 0.1 55.20
57 INT210989 Binding of FSCN1 and SP3 1 0.00 0.17 0.1 55.20
58 INT210994 Binding of SEA and SP3 1 0.00 0.17 0.1 55.20
59 INT349077 Binding of HLA-E and KLRD1 1 0.00 0.16 0 53.52
60 INT261883 PKD2 Positive_regulation of Localization of Ca2 1 0.02 0.67 0 50.04
61 INT222284 Negative_regulation of Casp1 Negative_regulation of Il18 1 0.01 0.79 0.46 50.00
62 INT222283 Negative_regulation of Casp1 Negative_regulation of Il1a 1 0.00 0.78 0.46 50.00
63 INT222295 Binding of CPP and Cebpz 1 0.00 0.73 0.05 50.00
64 INT328368 Ghrl Positive_regulation of INS 1 0.04 0.22 0 49.04
65 INT192678 PTEN Regulation of Dync1h1 1 0.02 0.5 0.03 47.76
66 INT183750 Binding of EPO and TF 1 0.42 1.21 0 47.36
67 INT186126 Binding of CD28 and CTLA4 9 0.52 4.13 3.12 46.00
68 INT82023 Binding of Ntrk1 and Ngf 5 0.53 3.48 3.92 45.28
69 INT270682 Binding of OLR1 and RENBP 1 0.00 0.76 0.08 45.20
70 INT132318 Ghrl Positive_regulation of Localization of GH1 5 0.32 4.49 0.84 44.52
71 INT214481 ROS1 Negative_regulation of Gene_expression of INS 1 0.00 0.37 0.22 42.56
72 INT198594 Binding of CFH and MIR1197 1 0.01 0.48 0 42.24
73 INT95552 Binding of Dbp and Shbg 3 0.01 2.09 0.32 40.80
74 INT191240 SAE1 Regulation of Localization of INS 1 0.08 1.15 0.3 39.12
75 INT313224 Negative_regulation of Binding of Cx3cr1 and Mcpt1 1 0.07 0.99 0.56 38.84
76 INT313223 Binding of Cx3cr1 and Mcpt1 1 0.06 0.99 0.56 38.32
77 INT246640 GAST Positive_regulation of NFASC 1 0.00 1.26 0.03 37.24
78 INT328381 Ghrl Positive_regulation of NPY 1 0.06 0.15 0.03 36.56
79 INT328369 Ghrl Negative_regulation of CRH 1 0.16 0.15 0 36.56
80 INT328375 Ghrl Negative_regulation of LEP 1 0.07 0.15 0 36.56
81 INT311223 GLP1R Regulation of Localization of GCG 1 0.16 0.74 0 36.12
82 INT344401 Agtr2 Positive_regulation of Gene_expression of Spp1 1 0.01 3.21 0 35.92
83 INT158400 Binding of CD80 and CD86 3 0.36 0.76 0.48 35.64
84 INT349079 Binding of CD80 and Cd86 1 0.22 0 0 35.64
85 INT328309 GHS Positive_regulation of Localization of GH1 1 0.04 0.99 0.12 33.60
86 INT277808 Binding of APCS and CD80 1 0.11 0.07 0 33.00
87 INT194647 Binding of CD28 and CD80 15 0.40 4.9 3.22 32.24
88 INT293312 CTLA4 Negative_regulation of Binding of CD28 and CD80 1 0.01 0.29 0.12 32.24
89 INT285748 PRL Positive_regulation of Positive_regulation of C6orf25 1 0.01 1.01 0.31 28.88
90 INT333393 CFD Positive_regulation of Gene_expression of Timp1 1 0.07 0.82 0.16 28.40
91 INT204159 Slc11a2 Regulation of Gene_expression of HAMP 1 0.11 1.08 0.14 26.24
92 INT198593 Binding of CFH and VHL 1 0.02 0.27 0 25.00
93 INT109502 GBE1 Negative_regulation of HIVEP1 1 0.00 1.85 0 25.00
94 INT207258 TXNIP Regulation of ZNF236 1 0.04 1.87 0 25.00
95 INT194927 Binding of CD40LG and Positive_regulation of CD79B 1 0.01 0.4 0 24.24
96 INT202985 Binding of F13A1 and TEX261 1 0.01 0.08 0 24.04
97 INT194926 Binding of CD40LG and Positive_regulation of BCR 1 0.04 0.39 0 23.24
98 INT334107 Binding of APC and APCS 1 0.16 1.52 0.04 21.48
99 INT172816 Crp Positive_regulation of Transcription of Nos3 1 0.06 0.91 0.1 17.00
100 INT172817 Crp Positive_regulation of Regulation of Nos3 1 0.09 0.84 0.1 17.00
101 INT172819 Crp Positive_regulation of Gene_expression of Nos3 1 0.06 0.91 0.1 17.00
102 INT172821 Crp Positive_regulation of Negative_regulation of Nos3 1 0.06 0.84 0.1 17.00
103 INT178097 Binding of EDN1 and EDNRA 7 0.21 5.97 0.62 16.96
104 INT194646 Binding of CD28 and CD86 7 0.40 2.69 2.21 16.00
105 INT293359 Binding of CD86 and KLRD1 1 0.00 0.38 0.16 16.00
106 INT54972 Binding of EDNRA and EDNRB 7 0.52 3.31 0.97 15.40
107 INT318298 MECOM Negative_regulation of Binding of CD28 1 0.00 1.08 0.18 15.20
108 INT223482 CRP Positive_regulation of GOPC 1 0.08 0.8 0.1 15.16
109 INT293361 Binding of CD80 and KLRD1 1 0.00 0.38 0.16 14.64
110 INT299785 CTLA4 Negative_regulation of Binding of CD28 2 0.17 1.8 0.5 14.48
111 INT274096 Binding of EDN1 and EDNRA Positive_regulation of Positive_regulation of EDN1 1 0.22 0.78 0 13.76
112 INT328373 Negative_regulation of Ghrl Positive_regulation of Localization of GH1 1 0.05 0.31 0.08 13.32
113 INT215096 Binding of Hmgb1 and Tlr2 9 0.38 11.61 1.61 13.00
114 INT355503 Positive_regulation of SCN10A Positive_regulation of Localization of NPY 1 0.17 1.32 0.22 12.16
115 INT202986 ANGPTL5 Positive_regulation of F13A1 1 0.01 0.07 0 11.36
116 INT202987 Binding of F2 and ANGPTL5 1 0.07 0.07 0 11.36
117 INT311227 INS Negative_regulation of HBA1 1 0.01 0.52 0.16 9.84
118 INT207785 Binding of RYR1 and Ap3d1 1 0.06 3.24 0.13 8.84
119 INT316373 Binding of Ren1 and Gopc 1 0.05 0.44 0 6.32
120 INT191590 Binding of AMBP and Arsb 1 0.00 1.82 0.04 5.92
121 INT195668 Binding of F2 and THBD 7 0.08 5.67 0.98 5.80
122 INT188692 Binding of Cd40 and Cd40lg 32 0.34 22.95 6.62 5.00
123 INT101942 Binding of CD40 and CD40LG 16 0.23 15.24 4.01 5.00
124 INT334928 Binding of pr and Aes 1 0.00 1.49 3.38 5.00
125 INT24388 CRH Positive_regulation of Localization of POMC 8 0.51 5.67 3.35 5.00
126 INT175329 Binding of ICAM1 and ITGAL 14 0.18 10.06 2.81 5.00
127 INT239037 Binding of Cd28 and Cd86 9 0.16 3.69 2.14 5.00
128 INT70043 IL6 Regulation of IL10 3 0.18 3.59 2.01 5.00
129 INT201940 Binding of IL8 and CXCL10 2 0.28 2.46 1.86 5.00
130 INT66504 Binding of Agt and Agtr1a 8 0.39 3.78 1.78 5.00
131 INT213071 IL6 Positive_regulation of Gene_expression of CRP 4 0.52 6.58 1.68 5.00
132 INT174503 Binding of HLA-B and KIR3DL1 6 0.37 3.48 1.61 5.00
133 INT198653 TNF Positive_regulation of MIF 1 0.15 3.81 1.55 5.00
134 INT172834 Binding of IL6 and T2dm2 1 0.00 6.4 1.4 5.00
135 INT265213 Binding of Ctla4 and Cd86 2 0.13 1.93 1.31 5.00
136 INT194513 Timp1 Negative_regulation of Cpox 1 0.00 0.9 1.31 5.00
137 INT186393 Binding of TNF and Tnfrsf1a 9 0.37 8.55 1.29 5.00
138 INT177232 ICAM1 Regulation of Gene_expression of Vcam1 1 0.03 5.52 1.28 5.00
139 INT172141 IL10 Negative_regulation of Gene_expression of HLA-DRA 2 0.14 0.89 1.23 5.00
140 INT83422 Binding of FANCB and IGHG3 3 0.12 5.09 1.22 5.00
141 INT225067 Binding of ETF1 and IGHG3 1 0.03 4.52 1.17 5.00
142 INT260810 Binding of CXCL10 and CCL2 1 0.10 1.37 1.12 5.00
143 INT225158 Binding of CDK2 and CDKN1A 7 0.30 3.26 1.02 5.00
144 INT74027 Creb1 Regulation of Jun 4 0.27 1.04 1.02 5.00
145 INT316128 TCF21 Negative_regulation of Gene_expression of HLA-DRA 1 0.07 0.13 0.99 5.00
146 INT265210 Binding of Ctla4 and Cd28 2 0.16 1.45 0.93 5.00
147 INT295552 Binding of Ghrl and Ghsr 7 0.40 1.64 0.88 5.00
148 INT189671 DAG1 Positive_regulation of PRKCA 3 0.12 0.71 0.82 5.00
149 INT73775 Binding of GH1 and GHR 4 0.35 0.68 0.8 5.00
150 INT81716 ITGAL Regulation of ITGB2 2 0.30 1.24 0.78 5.00
151 INT180496 Binding of CTS and PDXK 1 0.04 0.69 0.77 5.00
152 INT170127 Binding of ITGAL and PECAM1 2 0.01 2.71 0.75 5.00
153 INT152429 Ghrh Positive_regulation of Localization of Gh 4 0.37 0.56 0.75 5.00
154 INT213026 Hdl1 Positive_regulation of Nos3 5 0.16 7.92 0.73 5.00
155 INT205120 Binding of CD4 and CD8A 3 0.15 2.83 0.72 5.00
156 INT172097 Binding of HLA-E and Trav6-3 10 0.02 3.71 0.71 5.00
157 INT278077 Binding of BPHL and AURKC 1 0.16 4.29 0.69 5.00
158 INT28947 GH1 Positive_regulation of Gene_expression of IGF1 4 0.22 3.78 0.69 5.00
159 INT391 Binding of Agt and Ace 2 0.33 1.5 0.68 5.00
160 INT278827 Binding of EDN1 and EDNRB 3 0.17 2.7 0.67 5.00
161 INT170832 Cftr Regulation of Scnn1a 2 0.16 1.2 0.67 5.00
162 INT185997 Binding of FANCB and fc 2 0.01 2.51 0.63 5.00
163 INT172825 Binding of Crp and T2dm2 1 0.00 4.5 0.62 5.00
164 INT310712 Gabrg1 Positive_regulation of Gene_expression of PMP22 1 0.35 0.56 0.61 5.00
165 INT225065 Binding of ETF1 and FANCB 1 0.01 2.07 0.59 5.00
166 INT225083 Binding of ETF1 and fc 1 0.00 2.13 0.57 5.00
167 INT294708 CRP Positive_regulation of Gene_expression of VCAM1 2 0.31 1.92 0.56 5.00
168 INT195666 Binding of PROC and THBD 2 0.40 2.42 0.56 5.00
169 INT351581 Binding of ALB and GOPC 1 0.11 0 0.55 5.00
170 INT310701 RPLP0 Regulation of Positive_regulation of PGR 1 0.01 0.49 0.53 5.00
171 INT194595 Binding of TNFSF10 and TNFRSF10B 4 0.15 9.3 0.53 5.00
172 INT241247 Binding of Pkd2 and Trpv4 1 0.54 1.22 0.52 5.00
173 INT271344 MPO Regulation of Protein_catabolism of ACCS 1 0.02 2.42 0.51 5.00
174 INT254125 Binding of Bcl2a1a and Tlr4 Positive_regulation of Localization of Il6 1 0.00 1.23 0.5 5.00
175 INT254119 Binding of Bcl2a1a and Tlr4 1 0.01 1.34 0.49 5.00
176 INT278825 Positive_regulation of Binding of EDN1 and EDNRB 3 0.16 1.24 0.49 5.00
177 INT341428 EPO Positive_regulation of NGF 1 0.52 0.37 0.48 5.00
178 INT341427 EPO Positive_regulation of BDNF 1 0.52 0.36 0.48 5.00
179 INT328936 Binding of HLA-B and KIR3DS1 1 0.25 0.7 0.48 5.00
180 INT132792 IL4 Positive_regulation of IL6 4 0.28 1.81 0.47 5.00
181 INT341426 EPO Regulation of NGF 1 0.51 0.5 0.47 5.00
182 INT341425 EPO Regulation of BDNF 1 0.51 0.5 0.47 5.00
183 INT310711 Binding of RPLP0 and Gabrg1 1 0.04 0.37 0.45 5.00
184 INT328385 Binding of GHS and Ghrl 1 0.15 1.89 0.45 5.00
185 INT254120 Aliq1 Positive_regulation of Tbce 1 0.00 0.68 0.43 5.00
186 INT323484 Ghsr Positive_regulation of Localization of Ins1 1 0.27 0.87 0.43 5.00
187 INT213027 Binding of Apoa1 and Scarb1 6 0.09 7.52 0.43 5.00
188 INT241853 Binding of SLC40A1 and HAMP 3 0.41 5.35 0.43 5.00
189 INT328377 Binding of GAST and Ghrl 1 0.03 0.62 0.43 5.00
190 INT316121 IL10 Regulation of Gene_expression of HLA-DRA 1 0.09 0.46 0.42 5.00
191 INT328933 Binding of KIR2DS4 and TRGC1 1 0.09 0.76 0.41 5.00
192 INT328934 Binding of C2 and KIR2DS4 1 0.11 0.76 0.41 5.00
193 INT328935 Binding of HLA-G and KIR2DS4 1 0.39 0.75 0.41 5.00
194 INT209918 Positive_regulation of Nlrp3 Positive_regulation of Localization of Il1 1 0.42 1.06 0.4 5.00
195 INT323491 Olfr781 Positive_regulation of Localization of Ins1 1 0.01 0.87 0.4 5.00
196 INT275156 Agt Positive_regulation of Rac1 1 0.03 2.89 0.4 5.00
197 INT248146 PLA2G6 Negative_regulation of Phosphorylation of PLA2G4A 1 0.07 0.72 0.4 5.00
198 INT285746 IL6 Regulation of Localization of PRL 1 0.08 1.51 0.39 5.00
199 INT285749 IL6 Positive_regulation of Localization of PRL 1 0.08 1.51 0.39 5.00
200 INT173977 Binding of TNF and Ighg1 1 0.03 0.28 0.39 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Renal Failure. They are ordered first by their pain relevance and then by number of times they were reported in Renal Failure. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT45225 Localization of Hd 2 0.53 2.79 0.09 100.00
2 INT237355 Binding of Hd 1 0.09 1.99 0 100.00
3 INT192287 Gene_expression of Cpd 7 0.49 4.6 0 100.00
4 INT55315 Gene_expression of Tbp 32 0.74 14.6 1.17 100.00
5 INT1474 Regulation of Localization of Ins1 132 0.61 25.96 43.07 100.00
6 INT45226 Positive_regulation of Hd 8 0.31 3.78 0.16 100.00
7 INT9552 Positive_regulation of TNNI3 209 0.70 128.67 19.15 100.00
8 INT15872 Positive_regulation of EPO 74 0.70 45.35 6.67 100.00
9 INT169594 Binding of Cpd 1 0.41 2.79 0.17 100.00
10 INT1472 Positive_regulation of Ins1 349 0.69 146.2 86.36 100.00
11 INT251523 Localization of Nr6a1 1 0.08 1.07 0.15 100.00
12 INT251524 Gene_expression of Nr6a1 1 0.06 0.43 0 100.00
13 INT192288 Negative_regulation of Cpd 2 0.31 3.45 0.07 100.00
14 INT667 Negative_regulation of Hrh2 38 0.58 18.11 18.01 100.00
15 INT94026 Regulation of SERPING1 12 0.61 10.28 0.37 100.00
16 INT183842 Regulation of Nr6a1 1 0.06 0.73 0 100.00
17 INT27313 Negative_regulation of OAT 2 0.17 0.69 0.46 100.00
18 INT70955 Negative_regulation of Negative_regulation of Cd3e 1 0.41 0.47 0.09 100.00
19 INT70956 Negative_regulation of Negative_regulation of OAT 1 0.13 0.47 0.09 100.00
20 INT231889 Regulation of Positive_regulation of IAPP 1 0.26 0.55 0 100.00
21 INT914 Positive_regulation of GH1 292 0.69 100.7 84.91 99.98
22 INT242293 Positive_regulation of Positive_regulation of NPPB 5 0.56 2.92 0.33 99.98
23 INT5180 Binding of Serpinc1 27 0.36 13.39 2.47 99.98
24 INT70954 Negative_regulation of Cd3e 11 0.41 4.22 1.31 99.98
25 INT654 Localization of REN 250 0.81 75.12 47.86 99.96
26 INT14306 Positive_regulation of Gal 36 0.70 21.66 18.51 99.96
27 INT48004 Positive_regulation of Negative_regulation of PTGS1 12 0.49 4.07 5.87 99.96
28 INT69966 Positive_regulation of Negative_regulation of CPOX 11 0.45 6.18 4.64 99.96
29 INT12618 Positive_regulation of IAPP 54 0.68 32.03 2.29 99.92
30 INT24889 Negative_regulation of CABIN1 36 0.48 16.76 4.73 99.92
31 INT219646 Transcription of Hd 2 0.15 1.45 0.1 99.92
32 INT219644 Positive_regulation of Gene_expression of Hd 2 0.11 0.6 0.11 99.92
33 INT8465 Regulation of Ptgs1 100 0.57 36.03 44.41 99.92
34 INT155 Positive_regulation of Prl 1233 0.70 317.93 457.82 99.90
35 INT18897 Binding of CHGA 11 0.36 10.12 1.17 99.90
36 INT60966 Positive_regulation of Chn2 1 0.11 6.03 0.69 99.88
37 INT2649 Regulation of Calca 433 0.62 146.05 330.95 99.88
38 INT921 Regulation of GH1 172 0.60 52.88 51.04 99.84
39 INT18898 Positive_regulation of CHGA 38 0.67 28.99 4.86 99.84
40 INT16214 Localization of F13A1 36 0.74 21.8 4.87 99.84
41 INT15742 Negative_regulation of EPO 37 0.59 17.44 1.84 99.84
42 INT55611 Negative_regulation of H2-M3 6 0.46 0.59 3.84 99.84
43 INT985 Negative_regulation of GH1 213 0.57 89.53 32.39 99.84
44 INT60600 Binding of PSS 5 0.32 3.59 1.42 99.80
45 INT18012 Gene_expression of EPO 169 0.78 108.36 13.75 99.78
46 INT41892 Gene_expression of HBM 48 0.64 28.32 5.64 99.76
47 INT20631 Positive_regulation of CHKB 166 0.69 109.86 17.92 99.68
48 INT54238 Positive_regulation of UFM1 7 0.32 3.17 1.43 99.68
49 INT74446 Positive_regulation of Dync1h1 25 0.59 13 2.38 99.68
50 INT591 Negative_regulation of Serpinc1 44 0.57 31.73 8.82 99.66
51 INT219648 Gene_expression of Hd 16 0.27 8.78 0.68 99.64
52 INT307138 Positive_regulation of Negative_regulation of Ppig 2 0.06 1.01 0.18 99.64
53 INT17742 Localization of S100B 44 0.80 17.14 4.65 99.64
54 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73 99.62
55 INT1177 Positive_regulation of Positive_regulation of Ren 16 0.70 6.11 3 99.62
56 INT2296 Positive_regulation of Gene_expression of Prl 137 0.70 36.96 35.39 99.60
57 INT528 Gene_expression of Prl 693 0.78 217.18 192.2 99.60
58 INT1976 Regulation of Gene_expression of Prl 80 0.62 20.19 36 99.60
59 INT172328 Negative_regulation of Phl1 1 0.03 61.51 0.97 99.56
60 INT1190 Positive_regulation of F2 53 0.70 46.41 11.64 99.56
61 INT812 Localization of INS 1026 0.81 515.6 145.31 99.54
62 INT20509 Positive_regulation of Negative_regulation of Ins1 7 0.48 2.8 1.46 99.54
63 INT711 Positive_regulation of PIK3C2A 83 0.70 76.87 13.18 99.54
64 INT2890 Positive_regulation of MB 39 0.70 29.58 6.01 99.54
65 INT8112 Regulation of EPO 38 0.58 22.04 2.76 99.52
66 INT169697 Negative_regulation of Ephx2 35 0.59 38.21 5.92 99.50
67 INT724 Negative_regulation of Alb 151 0.59 93.57 29.65 99.48
68 INT107291 Positive_regulation of Ghrl 58 0.67 44.6 9.68 99.48
69 INT135720 Gene_expression of War 7 0.34 3.99 0.28 99.48
70 INT1126 Negative_regulation of CD79A 46 0.59 31.07 6 99.46
71 INT131788 Positive_regulation of NPPB 87 0.67 86.1 8.81 99.44
72 INT67868 Negative_regulation of Gene_expression of Tgfb1 18 0.43 14.27 5.16 99.44
73 INT13063 Binding of RHCE 16 0.38 6.54 1.22 99.44
74 INT126583 Positive_regulation of PARP1 50 0.68 41.44 7.78 99.44
75 INT546 Binding of ALB 311 0.48 85.98 60.14 99.42
76 INT1850 Binding of OXA1L 77 0.48 7.61 15.22 99.42
77 INT933 Regulation of Localization of Gtf3a 6 0.11 2.3 1.47 99.40
78 INT934 Regulation of Gtf3a 25 0.35 11.35 6.34 99.40
79 INT8662 Positive_regulation of EDN1 144 0.70 125.34 19.59 99.40
80 INT306913 Regulation of Ephx2 2 0.45 2.36 0.31 99.40
81 INT325481 Positive_regulation of Regulation of Ephx2 1 0.47 0.58 0.08 99.40
82 INT70242 Localization of HCC 18 0.66 23.95 2.35 99.38
83 INT30370 Negative_regulation of AMY2A 7 0.49 3.36 0.36 99.36
84 INT129539 Localization of SDMA 1 0.61 0.15 0.12 99.36
85 INT1199 Positive_regulation of INS 579 0.70 399.64 50.43 99.32
86 INT188760 Regulation of ZC3H12A 4 0.04 4.02 0.27 99.32
87 INT50580 Binding of PPIG 39 0.36 11.17 12.34 99.30
88 INT375 Positive_regulation of REN 293 0.70 152.46 47.55 99.28
89 INT10924 Positive_regulation of Sysbp1 25 0.04 11.12 7.35 99.28
90 INT46383 Negative_regulation of TRGC1 42 0.55 44.03 6.2 99.28
91 INT77490 Positive_regulation of Tnnc1 85 0.68 43.54 9.07 99.28
92 INT118371 Positive_regulation of Fgf23 15 0.69 25.34 0.85 99.28
93 INT135880 Positive_regulation of Gene_expression of Fgf23 4 0.46 7.52 0.29 99.28
94 INT43931 Binding of CFH 49 0.48 31.85 3.96 99.24
95 INT146898 Positive_regulation of Binding of CFH 3 0.44 2.01 0.17 99.24
96 INT48202 Gene_expression of Tgfb1 146 0.78 89.93 27.76 99.22
97 INT49610 Positive_regulation of Gene_expression of CTS 7 0.43 7.45 3.58 99.20
98 INT19763 Gene_expression of CTs 69 0.78 32.92 18.87 99.20
99 INT3987 Positive_regulation of IGHE 316 0.70 283.2 40.16 99.20
100 INT306910 Negative_regulation of Gene_expression of Ephx2 4 0.55 3.8 0.67 99.20
101 INT12163 Positive_regulation of OLAH 8 0.68 6.91 1.67 99.20
102 INT1200 Negative_regulation of Ins1 274 0.58 155.17 56.14 99.18
103 INT655 Positive_regulation of Localization of REN 86 0.70 32.41 13.56 99.18
104 INT4261 Positive_regulation of Localization of Adh1 11 0.61 2.04 3.49 99.18
105 INT2275 Negative_regulation of Localization of Ins1 183 0.59 51.02 44.94 99.16
106 INT28872 Positive_regulation of CSRP1 49 0.70 47.23 11.7 99.16
107 INT2604 Positive_regulation of Got1 223 0.70 154.78 49.51 99.08
108 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 99.08
109 INT7909 Positive_regulation of Positive_regulation of Got1 8 0.49 6.44 3.06 99.08
110 INT127039 Negative_regulation of Ppig 13 0.21 5.29 3.87 99.06
111 INT130765 Positive_regulation of ERAL1 7 0.49 7.07 1.54 99.04
112 INT219645 Regulation of Hd 2 0.10 1.26 0 99.00
113 INT107129 Positive_regulation of RLS 46 0.60 40.1 8.09 99.00
114 INT57562 Gene_expression of GLA 52 0.77 24.62 6.14 98.96
115 INT3971 Positive_regulation of Alb 175 0.70 98.46 36.45 98.96
116 INT2276 Regulation of Ins1 234 0.61 103.78 54.05 98.96
117 INT1261 Localization of Adh1 63 0.81 19.36 16.09 98.96
118 INT34869 Negative_regulation of PTGS2 778 0.59 366.76 319.85 98.92
119 INT122902 Positive_regulation of Gene_expression of Spp1 54 0.70 56.3 6.33 98.92
120 INT122901 Positive_regulation of Spp1 67 0.67 58.03 7.49 98.92
121 INT16357 Negative_regulation of NPPA 23 0.58 12.37 2.98 98.88
122 INT48766 Regulation of NOS1 73 0.61 37.01 24.59 98.84
123 INT28576 Binding of MLN 18 0.48 5.45 2.26 98.84
124 INT237356 Negative_regulation of Localization of Hd 1 0.09 0.82 0 98.80
125 INT161105 Gene_expression of Ephx2 20 0.78 17.84 3.58 98.80
126 INT34863 Positive_regulation of Negative_regulation of MTHFS 1 0.49 1.02 0.86 98.80
127 INT75742 Binding of RLS 86 0.42 95.27 19.04 98.80
128 INT5298 Negative_regulation of MTHFS 70 0.57 27.07 28.11 98.80
129 INT252 Localization of GH1 529 0.80 227.4 122.05 98.76
130 INT255 Regulation of Localization of GH1 89 0.62 18.71 35.3 98.76
131 INT249 Localization of GHRH 215 0.80 78.02 51.87 98.76
132 INT8111 Localization of EPO 32 0.81 19.53 2.54 98.76
133 INT673 Positive_regulation of B2m 24 0.68 24.24 4.82 98.76
134 INT254 Regulation of Localization of GHRH 30 0.60 5.17 11.46 98.76
135 INT3550 Negative_regulation of GLA 52 0.59 33.93 5.26 98.72
136 INT4683 Negative_regulation of PDXK 17 0.55 12.81 4.39 98.72
137 INT70134 Negative_regulation of TXK 124 0.23 81.96 9.59 98.72
138 INT670 Gene_expression of B2m 31 0.66 27.32 8.49 98.68
139 INT49706 Positive_regulation of TNNT2 22 0.69 12.65 1.56 98.68
140 INT158 Localization of Prl 2431 0.81 378.96 952.2 98.66
141 INT27710 Binding of B2m 5 0.36 3.54 0.53 98.66
142 INT188396 Positive_regulation of Positive_regulation of GOPC 13 0.42 1.78 1.21 98.66
143 INT2442 Localization of Mb 38 0.80 24.74 6.33 98.64
144 INT352801 Gene_expression of FGF21 1 0.73 22.78 0.05 98.64
145 INT10171 Binding of Gtf3a 33 0.36 19.84 5.1 98.64
146 INT17905 Binding of Fgg 9 0.05 4.79 1.68 98.64
147 INT10890 Binding of F8 11 0.36 7.27 1.15 98.64
148 INT84180 Binding of F5 22 0.48 18.6 0.49 98.64
149 INT92242 Binding of Plg 2 0.32 1.09 0.37 98.64
150 INT92243 Binding of F13a1 3 0.31 1.79 0.19 98.64
151 INT80187 Negative_regulation of Hd 3 0.58 2.45 0.09 98.62
152 INT703 Positive_regulation of Pth 177 0.70 127.09 27.26 98.60
153 INT132411 Positive_regulation of Ghrl 25 0.69 12.05 2.59 98.60
154 INT244571 Positive_regulation of HERPUD1 2 0.32 0.39 0.33 98.60
155 INT1114 Localization of Ins1 748 0.80 192.95 165.48 98.56
156 INT49750 Negative_regulation of CPOX 735 0.58 360.06 274.19 98.56
157 INT1988 Positive_regulation of Localization of Ins1 254 0.69 59.25 68.37 98.56
158 INT314 Positive_regulation of Ren 212 0.70 66.68 55.56 98.52
159 INT1793 Localization of CGA 379 0.81 67.38 114.69 98.52
160 INT162 Regulation of Prl 794 0.62 165.01 322.24 98.52
161 INT4612 Positive_regulation of Localization of CGA 64 0.64 8.51 22.39 98.52
162 INT136085 Binding of NSF 2 0.35 3.02 0.75 98.52
163 INT935 Localization of Gtf3a 124 0.70 35.72 43.3 98.40
164 INT147793 Localization of COPD 70 0.64 89.01 7.3 98.40
165 INT957 Positive_regulation of GHRH 136 0.70 36.84 40.52 98.32
166 INT110427 Gene_expression of Spp1 199 0.78 176.11 23.31 98.32
167 INT41721 Negative_regulation of MTOR 40 0.58 32.49 2.83 98.32
168 INT68187 Gene_expression of TNNT2 21 0.67 10.22 1.64 98.28
169 INT9126 Negative_regulation of Xdh 20 0.58 8.58 3.28 98.24
170 INT278981 Negative_regulation of JAK3 5 0.46 2.12 1.69 98.24
171 INT85829 Gene_expression of CA9 14 0.68 12.59 1.4 98.24
172 INT157666 Positive_regulation of GOPC 335 0.60 120.19 42.75 98.22
173 INT54924 Gene_expression of RLS 67 0.62 83.2 14.25 98.20
174 INT118373 Gene_expression of Fgf23 16 0.77 29.62 1.04 98.20
175 INT158693 Regulation of HDLBP 1 0.01 1.02 0.18 98.20
176 INT374 Positive_regulation of Ldha 212 0.70 107.08 47.43 98.20
177 INT13240 Gene_expression of TF 94 0.76 57.81 10.99 98.20
178 INT13085 Positive_regulation of ACE 50 0.70 44.2 8.31 98.16
179 INT2393 Positive_regulation of Mb 174 0.69 93.59 26.79 98.16
180 INT5793 Binding of CTS 110 0.48 63.91 40.62 98.16
181 INT613 Gene_expression of Alb 268 0.78 149.84 42.78 98.12
182 INT4853 Regulation of Hrh2 42 0.45 22.34 16.65 98.10
183 INT121513 Positive_regulation of A4GALT 21 0.63 16.06 1.59 98.08
184 INT1159 Negative_regulation of Agt 133 0.59 40.14 31.67 98.08
185 INT60279 Gene_expression of VHL 70 0.78 75.21 2.21 98.08
186 INT11685 Regulation of CSF2 99 0.59 58.82 15.9 98.00
187 INT20622 Gene_expression of LDHA 107 0.76 77.97 16.3 98.00
188 INT241236 Negative_regulation of Pkd2 11 0.43 1.82 0.39 98.00
189 INT351955 Gene_expression of Tro 1 0.44 1.38 0.33 98.00
190 INT78248 Negative_regulation of Cdkn2a 17 0.59 15.15 2.8 97.96
191 INT273501 Negative_regulation of HERPUD1 1 0.00 0.31 0.04 97.96
192 INT273604 Regulation of Negative_regulation of Cdkn2a 1 0.12 0.68 0.09 97.96
193 INT104298 Negative_regulation of ARSA 2 0.28 0.56 0.89 97.96
194 INT1533 Negative_regulation of AGT 105 0.42 46.54 16.92 97.92
195 INT34768 Negative_regulation of Negative_regulation of AGT 10 0.25 2.79 1.42 97.92
196 INT214619 Positive_regulation of Negative_regulation of AGT 1 0.04 0.98 0.13 97.92
197 INT32572 Gene_expression of Hctq1 4 0.38 1.49 0.87 97.84
198 INT7533 Gene_expression of Tlr4 720 0.78 343.22 121.57 97.72
199 INT7678 Localization of Alb 142 0.81 80.93 22.49 97.72
200 INT11567 Negative_regulation of Localization of Alb 17 0.48 7.69 1.56 97.72
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