D:Renal Osteodystrophy

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Disease Term
Synonyms Osteodystrophies Renal, Osteodystrophy Renal, RENAL OSTEODYSTROPHIES, Renal Rickets, Rickets Renal
Documents 94
Hot Single Events 20
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Renal Osteodystrophy. They are ordered first by their relevance to Renal Osteodystrophy and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT182775 Binding of PTH and ROS1 1 0.04 1.73 0.04 79.36
2 INT90387 ROS1 Positive_regulation of NFKB1 4 0.32 2.35 0.87 5.00
3 INT182771 ROS1 Positive_regulation of NFKB1 Positive_regulation of CRP 1 0.00 3.83 0.28 5.00
4 INT182772 ROS1 Positive_regulation of NFKB1 Positive_regulation of IL1B 1 0.00 1.89 0.14 5.00
5 INT182773 ROS1 Positive_regulation of NFKB1 Positive_regulation of IL6 1 0.00 1.9 0.14 5.00
6 INT182780 NFKB1 Positive_regulation of IL1B 1 0.00 1.8 0.14 5.00
7 INT182782 NFKB1 Positive_regulation of IL6 1 0.00 1.8 0.14 5.00
8 INT182784 IGF1 Positive_regulation of Gene_expression of INS 1 0.02 1.87 0 5.00
9 INT182804 Binding of ETV3 and T2DM 1 0.10 2.62 0 5.00
10 INT182778 IGF1 Positive_regulation of Gene_expression of ETV3 1 0.03 1.89 0 5.00
11 INT182774 Binding of ETV3 and SAE1 1 0.00 1.17 0 5.00
12 INT182783 INS Positive_regulation of Gene_expression of ETV3 1 0.01 1.89 0 5.00
13 INT182777 IAPP Positive_regulation of Gene_expression of ETV3 1 0.06 1.88 0 5.00
14 INT182776 IAPP Positive_regulation of Gene_expression of INS 1 0.03 1.87 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Renal Osteodystrophy. They are ordered first by their pain relevance and then by number of times they were reported in Renal Osteodystrophy. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT2649 Regulation of Calca 433 0.62 146.05 330.95 98.04
2 INT703 Positive_regulation of Pth 177 0.70 127.09 27.26 97.92
3 INT846 Positive_regulation of B2M 42 0.70 29.78 8.06 96.64
4 INT6624 Gene_expression of Pth 135 0.76 110.27 27.54 96.36
5 INT62570 Binding of Pth 48 0.48 26.45 4.85 96.36
6 INT744 Positive_regulation of PTH 130 0.70 95.02 11.7 95.32
7 INT53927 Positive_regulation of Localization of PTH 8 0.69 5.33 0.09 95.32
8 INT2544 Localization of PTH 39 0.81 30.55 2.22 94.92
9 INT6625 Negative_regulation of Pth 96 0.58 57.6 8.24 94.88
10 INT39911 Negative_regulation of Positive_regulation of Pth 5 0.41 2.57 0.37 94.88
11 INT3824 Negative_regulation of PTH 40 0.59 28.58 3.39 94.24
12 INT743 Negative_regulation of Salpa1 16 0.57 8.75 3.1 91.76
13 INT19395 Negative_regulation of Localization of Pth 11 0.58 10.16 0.55 90.60
14 INT4097 Localization of Pth 66 0.81 47.17 4.36 90.24
15 INT22715 Positive_regulation of Gene_expression of Pth 29 0.64 22.53 2.31 88.96
16 INT39500 Positive_regulation of Positive_regulation of Pth 14 0.48 9.75 1.28 88.96
17 INT36770 Positive_regulation of Localization of Pth 14 0.70 10.42 0.46 88.56
18 INT6514 Positive_regulation of Gene_expression of PTH 28 0.67 30.28 1.37 87.12
19 INT6512 Gene_expression of PTH 103 0.77 76.29 6.33 86.72
20 INT9500 Negative_regulation of Ceacam1 26 0.58 6.89 3.91 83.60
21 INT74563 Positive_regulation of Gene_expression of ROS1 258 0.61 168.18 34.08 79.36
22 INT69440 Gene_expression of ROS1 752 0.78 477.64 103.83 79.36
23 INT85388 Positive_regulation of Bmc1 8 0.25 3.74 0.56 75.00
24 INT172109 Gene_expression of SLC26A3 4 0.53 2.28 0.23 72.80
25 INT118054 Regulation of ARMC9 23 0.34 11.32 1.06 68.72
26 INT51014 Transcription of IL2 42 0.71 21.56 12.7 64.72
27 INT141367 Negative_regulation of Transcription of IL2 9 0.32 2.07 2.43 64.72
28 INT3343 Regulation of PTH 24 0.62 11.18 1.62 63.68
29 INT44638 Regulation of Regulation of PTH 1 0.27 0.74 0 63.68
30 INT52749 Gene_expression of alp 24 0.44 12.84 5.97 61.48
31 INT208004 Localization of RSS 2 0.12 1.62 0.53 42.60
32 INT62774 Positive_regulation of RSS 7 0.67 2 0.59 35.44
33 INT283496 Localization of CASR 2 0.76 2.04 0.41 34.64
34 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 5.00
35 INT17612 Gene_expression of CRP 676 0.78 580.61 119.03 5.00
36 INT60526 Gene_expression of IL10 449 0.78 292.71 107.84 5.00
37 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 5.00
38 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74 5.00
39 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 5.00
40 INT54571 Positive_regulation of NFKB1 263 0.70 138.99 87.32 5.00
41 INT17401 Gene_expression of IGF1 475 0.78 232.18 62.07 5.00
42 INT1199 Positive_regulation of INS 579 0.70 399.64 50.43 5.00
43 INT69437 Positive_regulation of ROS1 328 0.58 222.83 40.56 5.00
44 INT16960 Gene_expression of Crp 166 0.76 116.21 34.07 5.00
45 INT100861 Binding of CRP 179 0.48 175.2 26.45 5.00
46 INT9682 Positive_regulation of IGF1 238 0.70 120.03 26.36 5.00
47 INT130176 Positive_regulation of Gene_expression of CRP 125 0.66 137.06 25.9 5.00
48 INT28216 Gene_expression of HRAS 173 0.75 93.97 20.78 5.00
49 INT89484 Gene_expression of TNFRSF11B 119 0.76 53.57 19.67 5.00
50 INT756 Gene_expression of C3 138 0.75 100.6 19.2 5.00
51 INT83201 Gene_expression of NOS3 93 0.78 47.16 12.48 5.00
52 INT37541 Gene_expression of SPP1 113 0.77 68.54 11.35 5.00
53 INT62895 Gene_expression of NOSTRIN 51 0.75 28.8 10.68 5.00
54 INT110178 Phosphorylation of MAPK14 40 0.68 19.38 10.37 5.00
55 INT94784 Binding of ROS1 113 0.40 71.57 10.26 5.00
56 INT144689 Regulation of RCT 49 0.53 25.91 9.6 5.00
57 INT76091 Positive_regulation of NOS3 48 0.61 18.4 7.92 5.00
58 INT168418 Positive_regulation of RCT 32 0.55 20.2 4.07 5.00
59 INT175555 Gene_expression of CASR 17 0.78 14.83 3.73 5.00
60 INT87517 Gene_expression of LDLR 73 0.69 37.35 3.32 5.00
61 INT16130 Binding of IGF1 67 0.48 27.43 2.95 5.00
62 INT26996 Positive_regulation of Gene_expression of Crp 21 0.68 21.55 2.75 5.00
63 INT12618 Positive_regulation of IAPP 54 0.68 32.03 2.29 5.00
64 INT82166 Regulation of NOS3 14 0.54 7.57 2.08 5.00
65 INT59194 Gene_expression of STS 18 0.59 6.74 1.89 5.00
66 INT182297 Positive_regulation of Phosphorylation of MAPK14 7 0.42 3.36 1.53 5.00
67 INT18844 Binding of IAPP 11 0.36 11.01 1.45 5.00
68 INT158540 Negative_regulation of HTN1 4 0.34 7.25 1.22 5.00
69 INT158542 Gene_expression of HTN1 10 0.75 10.69 1.07 5.00
70 INT158541 Positive_regulation of Gene_expression of HTN1 3 0.40 5.88 0.97 5.00
71 INT99289 Localization of STS 8 0.79 6.5 0.92 5.00
72 INT182792 Regulation of STS 4 0.47 2.91 0.61 5.00
73 INT175558 Positive_regulation of CASR 5 0.47 3.55 0.6 5.00
74 INT158409 Gene_expression of T2DM 3 0.65 9.58 0.56 5.00
75 INT192808 Negative_regulation of Localization of PTH 6 0.59 7.31 0.45 5.00
76 INT182790 Positive_regulation of SAE1 3 0.49 3.18 0.39 5.00
77 INT182787 Binding of ETV3 14 0.37 25.44 0.37 5.00
78 INT182788 Gene_expression of ETV3 8 0.40 11.33 0.36 5.00
79 INT42244 Regulation of Gene_expression of PTH 5 0.45 3.95 0.34 5.00
80 INT131019 Binding of T2DM 6 0.47 6.97 0.31 5.00
81 INT182791 Binding of CPLX1 1 0.04 2.85 0.3 5.00
82 INT182752 Negative_regulation of T2DM 1 0.41 2.06 0.29 5.00
83 INT121834 Gene_expression of IAPP 24 0.66 20.96 0.26 5.00
84 INT6604 Binding of ITGA3 3 0.14 3.37 0.22 5.00
85 INT129762 Binding of HTN1 5 0.03 5.68 0.19 5.00
86 INT258920 Regulation of CASR 3 0.22 2.02 0.18 5.00
87 INT182794 Gene_expression of CPLX1 1 0.06 5.57 0.17 5.00
88 INT322288 Positive_regulation of Regulation of CASR 1 0.38 0.95 0.14 5.00
89 INT182800 Positive_regulation of ETV3 5 0.46 10.01 0.14 5.00
90 INT175557 Negative_regulation of Gene_expression of CASR 2 0.55 1.73 0.07 5.00
91 INT182785 Gene_expression of NHEJ1 1 0.01 1.08 0.06 5.00
92 INT182754 Positive_regulation of T2DM 1 0.67 4.5 0.03 5.00
93 INT182799 Positive_regulation of Gene_expression of CPLX1 1 0.04 1.49 0.03 5.00
94 INT182801 Positive_regulation of CPLX1 1 0.04 2.92 0.03 5.00
95 INT182753 Positive_regulation of Binding of 1 0.49 1.88 0 5.00
96 INT182786 Positive_regulation of Binding of ETV3 1 0.12 1.88 0 5.00
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