D:Reprotox - General 1

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pChart

Disease Term
Synonyms Abnormal Ejaculation, Abnormal Flow, Abnormal Menses, ABNORMAL MENSTRUAL CYCLE, ABNORMAL ORGASM, Abnormal Withdrawal Bleeding, ABNORMALITIES IN SEMEN VOLUME VISCOSITY SPERM COUNT MOTILITY, Abortion, Alteration Of The Timing Of The Cycle, Altered Menses, Amenorrhea
Documents 13462
Hot Single Events 200
Hot Interactions 169

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Reprotox - General 1. They are ordered first by their relevance to Reprotox - General 1 and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT220747 Binding of PCa and EGF 1 0.05 1.42 0.8 100.00
2 INT220745 EGF Positive_regulation of Positive_regulation of PCa 1 0.05 0.79 0.52 100.00
3 INT279414 Binding of CPOX and ACTR1B 1 0.04 1.55 0.4 100.00
4 INT220750 EGF Positive_regulation of PCa 1 0.05 0.45 0.23 100.00
5 INT123180 Bmp6 Positive_regulation of Lamtor1 1 0.01 0.61 0.14 100.00
6 INT123192 Bmp6 Positive_regulation of CDKN1A 1 0.18 0.61 0.14 100.00
7 INT123194 Bmp6 Positive_regulation of TAF9 1 0.18 0.61 0.14 100.00
8 INT123193 Bmp6 Positive_regulation of Negative_regulation of TAF9 1 0.18 0.61 0.14 100.00
9 INT126791 RASL12 Positive_regulation of ADRA1D 1 0.24 2.62 0.22 100.00
10 INT126795 RASL12 Positive_regulation of Hal 1 0.01 2.62 0.22 100.00
11 INT178442 Mapk1 Regulation of Gene_expression of Il6 1 0.03 0.59 0.03 100.00
12 INT54460 Binding of Abt1 and Chrna9 1 0.03 0.31 0.26 100.00
13 INT169128 Trove2 Negative_regulation of Gene_expression of AR 1 0.05 0.94 0.13 100.00
14 INT355663 Binding of CA5P and OAS1 1 0.00 0.47 0 100.00
15 INT131020 Binding of GNRH1 and T1DM 1 0.10 0.99 0.08 99.98
16 INT166162 Ccr9 Negative_regulation of Positive_regulation of Casp3 1 0.18 1.49 0.28 99.84
17 INT25036 TRH Regulation of Prl 4 0.27 1.75 1.09 99.84
18 INT315066 AKT1 Negative_regulation of PAR4 1 0.39 1.8 0.03 99.84
19 INT166154 Negative_regulation of Binding of Ccr9 and Ccl25 1 0.46 1.47 0.23 99.78
20 INT315068 Binding of AKT1 and PAR4 1 0.34 4.41 0 99.72
21 INT290443 Gene_expression of TIMP2 Negative_regulation of MMP2 1 0.06 1.56 0.13 99.68
22 INT315060 PAR4 Regulation of BCL2 1 0.53 0.48 0 99.64
23 INT278579 Esr1 Positive_regulation of Negative_regulation of Tac2 1 0.47 0.25 0.03 99.60
24 INT182496 AGT Positive_regulation of Phosphorylation of STAT3 1 0.03 0.79 0.12 99.52
25 INT166160 Binding of Ccr9 and Ccl25 1 0.40 5.06 0.84 99.50
26 INT352751 Pkd2 Regulation of Localization of Vegfa 1 0.11 0.47 0.1 99.36
27 INT352750 Pkd2 Positive_regulation of Vegfa 1 0.20 0.47 0.1 99.36
28 INT69279 Regulation of Binding of TSPO and Gabrg1 1 0.00 2.05 1.26 99.28
29 INT69280 Negative_regulation of Binding of TSPO and Gabrg1 1 0.00 1.03 0.63 99.28
30 INT69278 Binding of TSPO and Gabrg1 1 0.00 1.01 0.62 99.28
31 INT1392 Trh Regulation of Prl 15 0.29 2.47 4.29 99.28
32 INT60536 Gnrh1 Positive_regulation of Localization of Prl 2 0.22 1.12 0.6 99.20
33 INT326744 ARG1 Regulation of ARG2 1 0.50 1.04 0 99.08
34 INT177440 Binding of HPSE and Gnrh1 1 0.00 1.82 0.45 99.04
35 INT1390 Trh Positive_regulation of Prl 14 0.67 4.42 4.39 99.00
36 INT129364 Ea1 Positive_regulation of Localization of Ins1 1 0.02 0.49 0.2 98.80
37 INT160046 INPPL1 Regulation of Gene_expression of PTEN 1 0.41 0.6 0.42 98.72
38 INT160047 PTEN Regulation of Gene_expression of AKT1 1 0.33 0.6 0.42 98.72
39 INT160049 PTEN Regulation of Gene_expression of INPPL1 1 0.41 0.6 0.42 98.72
40 INT160048 INPPL1 Regulation of Gene_expression of AKT1 1 0.28 0.6 0.42 98.72
41 INT316249 DBT Regulation of TRPM8 1 0.08 1.28 0.15 98.64
42 INT60537 Gnrh1 Positive_regulation of Localization of FSHR 1 0.00 0.19 0.6 98.64
43 INT166155 Ccr9 Positive_regulation of Akt1 1 0.58 2.14 0.39 98.56
44 INT338013 Binding of Ngfrap1 and Ngfr 1 0.06 1.3 0 98.56
45 INT301122 Tgm7 Negative_regulation of Akt1 1 0.38 2.78 0.07 98.52
46 INT166157 Ccr9 Positive_regulation of Pik3r1 1 0.55 2.14 0.39 98.40
47 INT121651 Binding of CXCL12 and CXCR4 13 0.48 17.61 3.52 98.40
48 INT301127 Tgm7 Regulation of Positive_regulation of Akt1 1 0.47 0.48 0 98.20
49 INT117639 Serpini1 Negative_regulation of Cpox 1 0.00 0.64 0.72 98.16
50 INT124405 Binding of SST and SSTR1 1 0.01 0.5 0.41 98.04
51 INT166156 Ccr9 Positive_regulation of Mapk3 1 0.49 1.47 0.28 97.52
52 INT60538 Gnrh1 Positive_regulation of Localization of LHB 1 0.00 0.19 0.59 97.44
53 INT166164 Binding of Ccr9 and Ccl25 Positive_regulation of Akt1 1 0.47 1.47 0.28 97.28
54 INT185516 Binding of Igfbp2 and Csf2 1 0.14 0.29 0.17 97.20
55 INT178429 Negative_regulation of Mapk1 Negative_regulation of Positive_regulation of Eno2 1 0.02 0.73 0 97.12
56 INT166163 Binding of Ccr9 and Ccl25 Positive_regulation of Pik3r1 1 0.44 1.47 0.28 97.08
57 INT334025 Binding of CCR9 and Ccl25 1 0.40 0.96 0.4 96.88
58 INT334009 Binding of CCL25 and CCR9 1 0.40 0.96 0.4 96.88
59 INT326740 Gene_expression of AR Negative_regulation of Gene_expression of ARG2 1 0.24 0.8 0 96.84
60 INT326743 Gene_expression of AR Negative_regulation of Gene_expression of ARG1 1 0.32 0.8 0 96.84
61 INT337085 Binding of Cxcr4 and Mif 1 0.21 1.89 0.3 96.80
62 INT326739 IL8 Regulation of Gene_expression of ARG2 1 0.35 0.46 0.17 96.68
63 INT178434 Il6 Positive_regulation of Ar 1 0.01 0.93 0.08 96.52
64 INT235430 Il13 Positive_regulation of Gene_expression of Olr1 1 0.00 2.12 0.33 96.40
65 INT114967 ERI1 Negative_regulation of CPOX 1 0.00 0.25 0.14 95.60
66 INT107910 Binding of Tnfrsf11b and Tnfsf11 6 0.30 5.88 0.7 95.52
67 INT220744 EGF Positive_regulation of Gene_expression of KRT20 1 0.01 1.26 0.9 95.32
68 INT220749 EGF Positive_regulation of Positive_regulation of KRT20 1 0.01 0.61 0.32 95.32
69 INT220740 EGF Positive_regulation of Regulation of NAV1 1 0.31 0.61 0.32 95.32
70 INT221085 GHRH Positive_regulation of Gene_expression of IGF1 2 0.56 1.47 0.41 95.32
71 INT295430 BRD2 Positive_regulation of PLOD1 1 0.02 0.33 0.22 94.72
72 INT183269 Binding of CEBPB and CPOX 1 0.07 1.61 0.89 94.56
73 INT220527 Nme1 Negative_regulation of Positive_regulation of Vegfa 1 0.00 1.23 0.12 94.56
74 INT63103 AVP Regulation of OXT 1 0.28 0.68 1.02 94.32
75 INT107909 Binding of Tnfsf11 and Tnfrsf22 1 0.01 2.12 0.11 94.32
76 INT87922 Gm7869 Negative_regulation of Ptgs2 1 0.01 0.56 0.1 94.24
77 INT224293 AR Positive_regulation of Protein_catabolism of ESR1 1 0.24 0.4 0.07 93.80
78 INT247438 Binding of APOB and SACM1L 1 0.28 2 0 93.20
79 INT247435 Binding of APOB and SNRNP70 1 0.04 2.2 0 93.20
80 INT166153 Pik3r1 Regulation of Gene_expression of Ccr9 1 0.36 0.78 0.12 93.16
81 INT106630 Binding of GRK5 and PRKCA 1 0.16 0.82 0.19 93.08
82 INT178437 Mapk8 Positive_regulation of Jun 3 0.40 2.69 0.58 92.76
83 INT87921 Gm7869 Negative_regulation of Ptgs1 1 0.01 0.55 0.1 92.64
84 INT327198 DBT Positive_regulation of Gene_expression of ESRRA 1 0.00 0.42 0 92.64
85 INT220741 Binding of EGFR and SOAT1 1 0.02 0.37 0.49 92.52
86 INT247437 Binding of HSD11B1 and SACM1L 1 0.01 0.98 0 92.48
87 INT247442 Binding of HSD11B1 and SNRNP70 2 0.04 1.3 0 92.48
88 INT306566 Binding of IGHE and GOPC 1 0.06 0.18 0 92.16
89 INT71904 Binding of ESR1 and PGR 6 0.34 3.79 0.27 92.08
90 INT222301 Binding of ERBB2 and ESR1 5 0.36 5.07 0.29 92.08
91 INT338019 Egf Positive_regulation of AR 1 0.07 1.02 0.05 91.86
92 INT338020 Binding of AR and Ddr1 1 0.03 0.45 0 91.48
93 INT156879 Gene_expression of TP53 Negative_regulation of Positive_regulation of PDF 1 0.45 0.9 0.24 91.36
94 INT69826 Binding of SST and TBC1D4 1 0.08 1.49 0.56 91.24
95 INT187940 PHGDH Regulation of Gene_expression of RNU105A 1 0.32 0.94 0 91.16
96 INT326736 AR Regulation of Gene_expression of ARG2 1 0.34 0.43 0.03 91.12
97 INT220738 EGF Regulation of Gene_expression of EGFR 1 0.09 0.6 0.67 90.68
98 INT326742 AR Regulation of Gene_expression of ARG1 1 0.24 0.43 0.03 90.40
99 INT83410 Oxt Positive_regulation of Avp 1 0.20 0.35 0.28 90.24
100 INT326737 IL8 Positive_regulation of Gene_expression of ARG1 1 0.38 2.41 0.19 90.08
101 INT326749 IL8 Positive_regulation of Gene_expression of ARG2 1 0.39 1.96 0.03 90.08
102 INT338022 Cuedc2 Positive_regulation of Protein_catabolism of AR 1 0.23 0.29 0 90.00
103 INT178428 Regulation of Il6 Positive_regulation of Ar 1 0.01 0.47 0.04 89.64
104 INT222300 Binding of ERBB2 and PGR 2 0.34 1.89 0.17 89.56
105 INT156057 UMOD Regulation of GABRG3 1 0.01 0.54 0.14 89.20
106 INT295552 Binding of Ghrl and Ghsr 7 0.40 1.64 0.88 89.00
107 INT315061 PAR4 Positive_regulation of Gene_expression of TNF 1 0.10 1.95 0 89.00
108 INT279415 Gene_expression of CPOX Positive_regulation of VEGFC 1 0.04 2.23 0.07 88.84
109 INT279420 CPOX Positive_regulation of VEGFC 1 0.04 2.23 0.07 88.84
110 INT246016 Negative_regulation of Timp1 Negative_regulation of Gene_expression of Bcl2 1 0.03 1.07 0.13 88.80
111 INT246017 Timp1 Negative_regulation of Gene_expression of Bcl2 1 0.03 1.07 0.13 88.80
112 INT245076 CXCR4 Regulation of Gene_expression of VEGFA 1 0.16 1.05 0.03 88.80
113 INT301129 Tgm7 Negative_regulation of Akt1 Negative_regulation of Localization of Mmp2 1 0.38 0.55 0 88.80
114 INT75200 Umod Positive_regulation of Transcription of Psma4 1 0.02 1.04 0.92 88.72
115 INT326733 Negative_regulation of IL8 Negative_regulation of Gene_expression of ARG2 1 0.24 0.33 0.14 88.16
116 INT326735 Negative_regulation of IL8 Negative_regulation of Gene_expression of ARG1 1 0.32 0.33 0.14 88.16
117 INT319483 Binding of LCT and HSR 1 0.11 0.23 0 87.92
118 INT191692 Binding of Bag1 and gr 1 0.07 0.76 0.29 87.52
119 INT222466 Gnrh1 Regulation of Prl 1 0.14 1.16 0.07 87.12
120 INT156881 TP53 Positive_regulation of Positive_regulation of PDF 1 0.49 0.89 0.24 86.92
121 INT220743 Binding of AR and EGFR 1 0.01 0.46 0.1 86.76
122 INT338023 Psma7 Positive_regulation of AR 1 0.17 0.38 0 86.76
123 INT267812 Binding of ATF7IP and RLS 1 0.35 2.01 0.21 86.48
124 INT52836 ESR1 Positive_regulation of HSD17B7 1 0.43 0.41 0.09 86.20
125 INT178435 Mapk1 Regulation of Phosphorylation of Src 1 0.03 0.49 0.04 86.16
126 INT166785 NSMAF Negative_regulation of Gene_expression of PCNA 1 0.30 1.26 0.08 85.60
127 INT166786 NSMAF Positive_regulation of Gene_expression of IFI27 1 0.34 1.22 0.08 85.60
128 INT326738 Gene_expression of IL8 Positive_regulation of Gene_expression of ARG1 1 0.26 0.41 0 85.52
129 INT314745 Binding of TP53 and Brca1 1 0.18 1.17 0 85.32
130 INT192913 Binding of ESR1 and HAMP 1 0.02 0.72 0 85.08
131 INT192915 Binding of ESR1 and MIER3 1 0.00 0.72 0 85.08
132 INT312693 Binding of CCR6 and CCL20 2 0.34 2.33 0.53 84.72
133 INT192912 Binding of HAMP and MIER3 1 0.01 0.71 0 84.72
134 INT316250 Negative_regulation of DBT Negative_regulation of Gene_expression of TRPM8 1 0.11 1.06 0 84.44
135 INT44441 GNRH1 Positive_regulation of Localization of FSHR 2 0.15 0.86 0.26 84.40
136 INT270758 GNRHR Positive_regulation of Localization of FSHR 1 0.08 0.68 0 84.40
137 INT291546 St8sia2 Positive_regulation of Sec22b 1 0.02 0.35 0.11 84.24
138 INT291550 St8sia2 Positive_regulation of Pik3cb 1 0.05 0.36 0.11 84.24
139 INT291547 Binding of St8sia2 and Positive_regulation of Sec22b 1 0.02 0.35 0.11 84.24
140 INT211883 Binding of RET and CDCP1 1 0.00 2.12 0 84.16
141 INT203587 MCF2 Negative_regulation of Gene_expression of CPOX 1 0.00 0.6 0 84.00
142 INT220739 EGF Positive_regulation of Transcription of NAV1 1 0.31 0.16 0.83 83.92
143 INT178441 Binding of Ar and Sra1 1 0.00 0.45 0.04 83.84
144 INT260131 CGA Negative_regulation of OFC1 1 0.01 0.17 0 83.52
145 INT312803 F2 Positive_regulation of NPEPPS 1 0.01 1.32 0.32 83.48
146 INT312802 F2 Positive_regulation of Binding of NPEPPS 1 0.01 1.33 0.32 83.48
147 INT211882 Binding of KIT and CDCP1 1 0.00 2.1 0 82.88
148 INT178439 Binding of Ar and Src 1 0.01 0.44 0.04 82.60
149 INT338018 Binding of AR and Flna 1 0.11 0.33 0 82.48
150 INT338021 Binding of Flna and Regulation of Transcription of AR 1 0.14 0.33 0 82.48
151 INT59155 Binding of Adcyap1 and Vip 2 0.34 0.08 0.55 82.48
152 INT213933 AR Negative_regulation of Cyp19a1 1 0.07 0.79 0.07 82.40
153 INT280843 Binding of Crem and Crh 1 0.03 0.22 0.04 82.40
154 INT222299 Binding of CYP19A1 and AIS 2 0.25 1.65 0.31 82.32
155 INT211860 PLOD1 Regulation of AGRP 1 0.07 0.15 0.14 81.96
156 INT278015 Gh Regulation of Ins1 1 0.10 1.47 0.27 81.96
157 INT129074 Binding of GRP and TCHP 1 0.00 0.5 0.12 81.92
158 INT129094 Binding of GRP and Pik3r1 1 0.00 0.49 0.12 81.92
159 INT129073 Binding of GRP and PIK3CG 1 0.00 0.49 0.12 81.92
160 INT129092 Binding of GRP and Lyn 1 0.00 0.48 0.12 81.92
161 INT121314 Tgfb1 Positive_regulation of Egfr 1 0.08 0.16 0 81.88
162 INT272755 Binding of DBI and Ptger2 1 0.00 1.13 0.33 81.52
163 INT140447 Ngf Regulation of Scn9a 1 0.69 0.16 0.84 81.48
164 INT297351 EWSR1 Positive_regulation of PPARA 1 0.41 1.81 0.33 81.40
165 INT280817 Binding of Cdx1 and Crh 1 0.02 0.21 0.04 81.40
166 INT246019 Timp1 Negative_regulation of Localization of TNF 1 0.23 1.05 0.14 81.36
167 INT246018 Timp1 Negative_regulation of Localization of Il1 1 0.01 1.05 0.14 80.96
168 INT263339 Ptger2 Regulation of Ppara 1 0.09 0.44 0.21 80.64
169 INT263337 Ptger4 Regulation of Ppara 1 0.02 0.3 0.04 80.64
170 INT68004 Binding of Hba-a1 and Vim 1 0.00 1.3 0.08 79.92
171 INT68008 Binding of DES and Hba-a1 1 0.03 1.3 0.08 79.52
172 INT198382 Binding of AR and SRD5A1 2 0.06 0.84 0.17 79.44
173 INT121320 Negative_regulation of Egfr Negative_regulation of Tgfb1 Positive_regulation of Ercc1 1 0.07 0.08 0 79.24
174 INT121315 Negative_regulation of Egfr Negative_regulation of Ercc1 1 0.42 0.08 0 79.24
175 INT121319 Negative_regulation of Egfr Negative_regulation of Tgfb1 Positive_regulation of Xrcc1 1 0.07 0.08 0 79.24
176 INT278018 Gh Negative_regulation of Phosphorylation of Ins1 1 0.13 1.5 0.29 79.04
177 INT350106 Binding of SLC4A3 and SLC4A1 1 0.13 2.78 0.09 78.40
178 INT353438 Rnd3 Negative_regulation of Rock1 1 0.26 2.08 0 78.24
179 INT129091 Binding of PIK3CG and Lyn 1 0.00 0.47 0.12 77.68
180 INT129075 Binding of Pik3r1 and Lyn 1 0.00 0.47 0.12 77.68
181 INT129093 Binding of Lyn and TCHP 1 0.00 0.49 0.12 77.68
182 INT240271 Binding of GDNF and RET 1 0.09 1.04 0 77.60
183 INT121316 Tgfb1 Negative_regulation of Xrcc1 1 0.06 0.08 0 77.32
184 INT121318 Tgfb1 Negative_regulation of Ercc1 1 0.06 0.08 0 77.32
185 INT315054 TP53 Positive_regulation of MIR34A 1 0.02 0.47 0 76.96
186 INT268678 Binding of HDAC2 and NCOR2 1 0.18 2.67 0.07 76.88
187 INT156087 Binding of AKR1C3 and Akr1c1 1 0.05 0.31 0.3 76.72
188 INT156083 Binding of AKR1C2 and AKR1C3 1 0.05 0.31 0.3 76.72
189 INT156084 Binding of PTGS2 and AKR1C3 1 0.02 0.31 0.3 76.72
190 INT156082 Binding of PTGS1 and AKR1C3 1 0.01 0.31 0.3 76.72
191 INT121313 Tgfb1 Positive_regulation of Ercc1 1 0.07 0.08 0 76.72
192 INT121317 Tgfb1 Positive_regulation of Xrcc1 1 0.07 0.08 0 76.72
193 INT134311 Tnf Positive_regulation of Protein_catabolism of Nfkbia 1 0.18 0.57 0.88 76.32
194 INT306261 AKT2 Negative_regulation of Phosphorylation of FOXO1 1 0.25 0.41 0.17 76.24
195 INT263340 Ptger2 Positive_regulation of IL8 1 0.01 0.15 0.1 76.20
196 INT268679 Binding of HDAC1 and NCOR2 3 0.17 2.8 0.07 76.08
197 INT268676 Binding of HDAC1 and BCOR 1 0.01 1.31 0.04 76.08
198 INT329745 AKT1 Negative_regulation of BAD 1 0.03 1.43 0 75.96
199 INT289765 Akt1 Regulation of Phosphorylation of Gsk3a 1 0.05 0.45 0.11 75.76
200 INT289768 Akt1 Regulation of Phosphorylation of Gsk3b 1 0.04 0.45 0.11 75.76

Single Events

The table below shows the top 200 pain related interactions that have been reported for Reprotox - General 1. They are ordered first by their pain relevance and then by number of times they were reported in Reprotox - General 1. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT281928 Gene_expression of ARG2 3 0.77 63.17 2.14 100.00
2 INT155 Positive_regulation of Prl 1233 0.70 317.93 457.82 100.00
3 INT162 Regulation of Prl 794 0.62 165.01 322.24 100.00
4 INT1705 Gene_expression of pCA 126 0.65 88.65 34.81 100.00
5 INT156 Negative_regulation of Prl 542 0.59 131.97 192.24 100.00
6 INT5206 Gene_expression of AR 316 0.78 113.83 27.29 100.00
7 INT30610 Localization of PCa 35 0.65 13.91 4.25 100.00
8 INT14724 Negative_regulation of CYP19A1 233 0.59 96.56 18.26 100.00
9 INT46460 Gene_expression of NAV1 288 0.78 135.51 305.75 100.00
10 INT8905 Gene_expression of EDN1 215 0.78 157.1 34.19 100.00
11 INT263822 Positive_regulation of Gene_expression of LOX 8 0.50 11 1.06 100.00
12 INT34869 Negative_regulation of PTGS2 778 0.59 366.76 319.85 100.00
13 INT69648 Positive_regulation of CA5P 10 0.58 6.41 1.57 100.00
14 INT1168 Binding of PROC 62 0.38 44.15 9.04 100.00
15 INT159 Negative_regulation of Localization of Prl 416 0.59 55.34 171.8 100.00
16 INT32117 Binding of us 5 0.23 3.61 3.91 100.00
17 INT161 Regulation of Localization of Prl 615 0.62 65.37 298.66 100.00
18 INT10754 Positive_regulation of Gene_expression of PCa 18 0.41 21.81 4.17 100.00
19 INT120811 Gene_expression of Gopc 1174 0.59 428.49 150.55 100.00
20 INT5137 Binding of PCa 45 0.47 16.91 18.47 100.00
21 INT129304 Gene_expression of CA5P 8 0.57 4.52 0.57 100.00
22 INT1704 Positive_regulation of PCa 68 0.59 34.92 23.36 100.00
23 INT5204 Positive_regulation of Gene_expression of AR 60 0.67 23.54 3.53 100.00
24 INT27260 Gene_expression of DYNLL1 8 0.75 7.72 2.78 100.00
25 INT10675 Gene_expression of DBI 28 0.67 19.74 6.07 100.00
26 INT1703 Regulation of PCa 52 0.52 23.65 20.6 100.00
27 INT9832 Gene_expression of Shbg 96 0.75 56.71 12.19 100.00
28 INT10753 Regulation of Gene_expression of PCa 8 0.23 7.16 1.49 100.00
29 INT205165 Negative_regulation of ACTR1B 5 0.22 4.94 0.37 100.00
30 INT100046 Gene_expression of BTG2 16 0.20 10.81 1.95 100.00
31 INT175652 Positive_regulation of BPHL 9 0.44 17.98 1.14 100.00
32 INT186523 Binding of ETFDH 10 0.25 5.63 0.72 100.00
33 INT84727 Negative_regulation of Gene_expression of AR 38 0.58 12.46 4.63 100.00
34 INT1893 Localization of Gh 1041 0.79 340.23 256.58 100.00
35 INT244700 Regulation of Gene_expression of ARG1 2 0.60 3.09 0.04 100.00
36 INT355346 Negative_regulation of Gene_expression of NOG 1 0.20 5.87 0.33 100.00
37 INT15390 Positive_regulation of Edn1 64 0.70 47.36 23.8 100.00
38 INT3602 Negative_regulation of Shbg 148 0.53 69.05 11.65 100.00
39 INT96258 Positive_regulation of Pik3cd 14 0.43 8.74 5.16 100.00
40 INT203610 Protein_catabolism of CPOX 1 0.15 1.92 0 100.00
41 INT110944 Transcription of PCA 3 0.52 2.49 1.13 100.00
42 INT337985 Negative_regulation of Gene_expression of Hmgb2 1 0.37 0.71 0 100.00
43 INT337976 Transcription of Cuedc2 1 0.40 0.9 0 100.00
44 INT337978 Transcription of Psma7 1 0.46 0.9 0 100.00
45 INT1976 Regulation of Gene_expression of Prl 80 0.62 20.19 36 100.00
46 INT35526 Binding of Eef1a2 14 0.34 5.82 1.61 100.00
47 INT1767 Positive_regulation of PROC 83 0.67 54.14 17 100.00
48 INT27687 Regulation of Cp 20 0.53 9.75 10.8 100.00
49 INT68755 Regulation of us 3 0.04 1.24 0.84 100.00
50 INT1706 Negative_regulation of PCa 33 0.47 10.7 15.27 100.00
51 INT104207 Positive_regulation of Gene_expression of Tnfsf11 43 0.69 25.8 7.35 100.00
52 INT69649 Regulation of CA5P 3 0.20 2.56 0.81 100.00
53 INT10676 Negative_regulation of DBI 10 0.37 7 3.65 100.00
54 INT230670 Positive_regulation of Gene_expression of Ccnh 2 0.49 0.87 0 100.00
55 INT45112 Positive_regulation of PRB1 20 0.60 6.49 2.85 100.00
56 INT11728 Binding of NUPL2 3 0.47 3.28 0.42 100.00
57 INT5781 Gene_expression of Edn1 190 0.78 99.1 46 100.00
58 INT135234 Regulation of ETFDH 13 0.29 10.8 3.4 100.00
59 INT60636 Positive_regulation of Mst1 3 0.35 1.11 0.39 100.00
60 INT7675 Gene_expression of ENG 146 0.77 45.35 34.6 100.00
61 INT23375 Binding of ENG 17 0.47 6.02 6.46 100.00
62 INT206749 Gene_expression of ACPP 4 0.40 2.61 0.37 100.00
63 INT9295 Regulation of MAOB 12 0.56 3.32 3.6 100.00
64 INT1894 Negative_regulation of Localization of Gh 168 0.58 64.12 43.56 100.00
65 INT1768 Negative_regulation of Positive_regulation of PROC 5 0.41 2.8 1.51 100.00
66 INT227758 Positive_regulation of Localization of Best1 3 0.07 1.95 0 100.00
67 INT204209 Positive_regulation of Protein_catabolism of PCA 1 0.40 0.73 0.1 100.00
68 INT204210 Protein_catabolism of PCA 1 0.71 0.73 0.1 100.00
69 INT30443 Positive_regulation of AIS 30 0.54 22.59 7.2 100.00
70 INT9146 Gene_expression of FOLH1 26 0.75 10.76 2.85 100.00
71 INT767 Localization of Gnrhr 565 0.80 106.68 214.57 100.00
72 INT69653 Positive_regulation of ABTB1 3 0.42 3.69 0.37 100.00
73 INT9656 Regulation of Gene_expression of Il6 57 0.62 33.3 17.71 100.00
74 INT90762 Regulation of Gene_expression of Pcsk1 2 0.22 0.58 0.44 100.00
75 INT266086 Negative_regulation of Gene_expression of DBI 1 0.07 1.16 0.1 100.00
76 INT15590 Negative_regulation of us 1 0.01 0.51 0.35 100.00
77 INT175653 Localization of PCAP 8 0.59 3.83 2.46 100.00
78 INT42032 Localization of PNLIP 4 0.14 3.44 0.41 100.00
79 INT329263 Localization of Prcc 1 0.11 0.9 0.07 100.00
80 INT355351 Positive_regulation of Localization of NOG 1 0.23 1.11 0.09 100.00
81 INT45672 Negative_regulation of Serpina6 5 0.43 1.66 2.08 100.00
82 INT1448 Binding of Adra1a 23 0.48 1.41 8.01 100.00
83 INT127200 Localization of Mcf2l 7 0.64 4.8 3.25 100.00
84 INT140993 Negative_regulation of Positive_regulation of Stat3 6 0.38 3.39 2.39 100.00
85 INT8949 Negative_regulation of Klra3 4 0.23 0.19 2.34 100.00
86 INT56446 Positive_regulation of Positive_regulation of Icam1 7 0.40 8.84 1.64 100.00
87 INT45674 Regulation of Gene_expression of Serpina6 3 0.14 0.86 1.14 100.00
88 INT45675 Regulation of Gene_expression of Shbg 6 0.15 4.65 1.03 100.00
89 INT59786 Binding of SERPINE2 4 0.32 2.98 0.79 100.00
90 INT18657 Negative_regulation of Binding of Adra1a 2 0.43 0.17 0.56 100.00
91 INT197024 Binding of STIP1 11 0.35 10.84 0.52 100.00
92 INT158 Localization of Prl 2431 0.81 378.96 952.2 99.98
93 INT5131 Gene_expression of GNRH1 109 0.78 28.79 23.94 99.98
94 INT8347 Gene_expression of SST 181 0.78 104.59 65.45 99.98
95 INT159936 Positive_regulation of Shc4 8 0.50 3.43 0.04 99.98
96 INT11519 Negative_regulation of Coc 8 0.50 3.96 2.74 99.98
97 INT38493 Positive_regulation of LOC246267 2 0.00 0.95 0.43 99.98
98 INT132725 Regulation of DDA1 1 0.02 0.45 0.42 99.98
99 INT131019 Binding of T2DM 6 0.47 6.97 0.31 99.98
100 INT1793 Localization of CGA 379 0.81 67.38 114.69 99.96
101 INT467 Gene_expression of POMC 1048 0.78 332.8 394.16 99.96
102 INT57642 Gene_expression of PCSK1 26 0.76 5.09 4.28 99.96
103 INT109806 Positive_regulation of Ppl 3 0.25 2.46 0.99 99.96
104 INT272437 Positive_regulation of Transcription of PROK2 1 0.30 1.67 0 99.96
105 INT110599 Gene_expression of Bglap 49 0.74 41.23 6.97 99.96
106 INT914 Positive_regulation of GH1 292 0.69 100.7 84.91 99.96
107 INT6278 Negative_regulation of Gene_expression of Pomc 35 0.59 11.07 14.8 99.96
108 INT7395 Localization of GNRH1 399 0.81 62.88 117.68 99.92
109 INT528 Gene_expression of Prl 693 0.78 217.18 192.2 99.92
110 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73 99.92
111 INT7394 Positive_regulation of Localization of GNRH1 67 0.69 7.22 25.29 99.92
112 INT52732 Negative_regulation of CRP 169 0.59 138.47 40.33 99.92
113 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65 99.92
114 INT84722 Regulation of Gene_expression of AR 20 0.61 7.73 1.69 99.92
115 INT3546 Binding of Oxt 54 0.48 9.75 10.81 99.92
116 INT54458 Binding of Chrna9 10 0.36 0.88 3.57 99.92
117 INT96142 Binding of ASPSCR1 4 0.36 3.22 1.31 99.92
118 INT201847 Positive_regulation of CYR61 1 0.50 5.22 1.09 99.92
119 INT7397 Negative_regulation of Localization of GNRH1 86 0.59 15.45 29.78 99.90
120 INT148 Positive_regulation of Gnrhr 182 0.70 47.44 79.64 99.90
121 INT4421 Positive_regulation of LAP 12 0.44 11.06 1.74 99.90
122 INT50670 Gene_expression of CPOX 763 0.76 442.13 195.02 99.88
123 INT915 Positive_regulation of PRL 342 0.70 141.96 104.31 99.88
124 INT131415 Gene_expression of POU4F1 1 0.60 1.87 0.36 99.88
125 INT6580 Negative_regulation of Ptgs1 929 0.59 381.53 376.26 99.88
126 INT13499 Gene_expression of Agtr2 68 0.76 35.64 10.59 99.88
127 INT44147 Positive_regulation of Gene_expression of Agtr2 11 0.50 9.02 1.28 99.88
128 INT244704 Gene_expression of ARG1 65 0.75 37.74 1.9 99.86
129 INT86024 Gene_expression of PPARA 736 0.78 497.93 91.14 99.86
130 INT2614 Gene_expression of CGA 187 0.78 105.89 24.77 99.86
131 INT129883 Gene_expression of Dkk1 56 0.77 45.42 12.52 99.86
132 INT937 Positive_regulation of Oxt 195 0.70 37.82 49.3 99.86
133 INT3057 Gene_expression of Ptgfr 60 0.58 14.54 11.73 99.86
134 INT5379 Gene_expression of Fos 656 0.78 255.5 292.54 99.86
135 INT170335 Gene_expression of INCENP 176 0.54 91.62 15.31 99.86
136 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74 99.86
137 INT88318 Gene_expression of CXCR4 208 0.77 189.67 31.72 99.86
138 INT5380 Positive_regulation of Gene_expression of Fos 243 0.70 105.65 131.05 99.86
139 INT8528 Negative_regulation of Gene_expression of Fos 100 0.59 41.15 55.6 99.86
140 INT101592 Gene_expression of TRPM8 82 0.78 70.61 22.89 99.84
141 INT90673 Gene_expression of LOX 66 0.65 69.71 12.18 99.84
142 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 99.84
143 INT85952 Positive_regulation of AR 168 0.67 64.36 20.66 99.84
144 INT326769 Regulation of Gene_expression of ARG2 1 0.61 9.7 0.54 99.84
145 INT281922 Positive_regulation of Gene_expression of ARG2 2 0.69 10.45 0.5 99.84
146 INT326778 Negative_regulation of Gene_expression of ARG2 1 0.58 7.05 0.03 99.84
147 INT912 Localization of FSHR 91 0.79 23.61 15.58 99.84
148 INT96913 Positive_regulation of Mapk8 179 0.69 130.44 32.2 99.84
149 INT10832 Gene_expression of IL8 1050 0.78 698.72 270 99.84
150 INT94388 Gene_expression of GDF15 124 0.77 79.48 31.42 99.84
151 INT103924 Positive_regulation of Akt1 359 0.69 158.94 60.34 99.84
152 INT739 Negative_regulation of POMC 358 0.59 102.28 166.77 99.84
153 INT326781 Transcription of ARG2 1 0.71 3.93 0 99.84
154 INT355345 Localization of NOG 1 0.37 16.14 0.71 99.84
155 INT109315 Gene_expression of Mapk8 70 0.78 45.46 11.65 99.84
156 INT55344 Gene_expression of Ros1 396 0.54 217.64 59.98 99.84
157 INT82434 Positive_regulation of LEP 117 0.70 95.45 20.22 99.84
158 INT5372 Localization of LHB 55 0.68 9.47 19 99.84
159 INT9659 Gene_expression of Il6 991 0.78 715.11 265.57 99.84
160 INT5710 Negative_regulation of Localization of Lhb 146 0.57 20.51 58.33 99.84
161 INT119018 Gene_expression of TREH 22 0.65 12.44 1.95 99.84
162 INT119025 Gene_expression of NOTCH1 46 0.75 31.32 2.64 99.84
163 INT3183 Negative_regulation of MRXS5 15 0.41 6.56 3.45 99.84
164 INT72060 Positive_regulation of Gene_expression of Ros1 127 0.41 76.76 20.91 99.84
165 INT101593 Positive_regulation of Gene_expression of TRPM8 16 0.70 13.79 4.23 99.84
166 INT93534 Gene_expression of Tnfsf11 185 0.77 119.26 33.66 99.84
167 INT117754 Gene_expression of NHS 34 0.57 9.27 3.28 99.84
168 INT17612 Gene_expression of CRP 676 0.78 580.61 119.03 99.84
169 INT2296 Positive_regulation of Gene_expression of Prl 137 0.70 36.96 35.39 99.84
170 INT263824 Positive_regulation of LOX 4 0.34 5.28 0.27 99.84
171 INT94390 Positive_regulation of Gene_expression of GDF15 67 0.69 45.5 14.74 99.84
172 INT173422 Gene_expression of ETFDH 11 0.45 5.78 0.78 99.84
173 INT337998 Gene_expression of Psma7 1 0.68 1.02 0 99.84
174 INT72138 Gene_expression of Pthlh 18 0.75 17.68 1.49 99.84
175 INT102638 Regulation of VDR 21 0.44 9.92 2.54 99.84
176 INT337995 Positive_regulation of Gene_expression of Ngfrap1 1 0.61 1.35 0 99.84
177 INT4612 Positive_regulation of Localization of CGA 64 0.64 8.51 22.39 99.84
178 INT65600 Positive_regulation of Casp3 376 0.70 198.44 128.03 99.84
179 INT6196 Regulation of Nppa 83 0.62 30.31 30.18 99.84
180 INT168409 Positive_regulation of Ccl5 47 0.64 45.84 10.83 99.84
181 INT923 Positive_regulation of Localization of FSHR 14 0.43 2.48 4.96 99.84
182 INT172527 Gene_expression of IGFBP7 6 0.60 4.76 0.36 99.84
183 INT136925 Gene_expression of NOTCH2 2 0.61 0.56 0.05 99.84
184 INT89395 Negative_regulation of AKT1 127 0.58 70.27 12.54 99.84
185 INT6129 Positive_regulation of Localization of AVP 63 0.70 30.44 16.64 99.84
186 INT337984 Gene_expression of Hmgb2 1 0.67 0.35 0 99.84
187 INT120775 Gene_expression of Sp6 7 0.66 0.98 0.81 99.84
188 INT109535 Gene_expression of Vegfa 116 0.75 84.61 14.89 99.84
189 INT130 Negative_regulation of OXTR 19 0.43 4.63 4.96 99.84
190 INT11371 Positive_regulation of Localization of LHB 8 0.47 1.4 2.93 99.84
191 INT165490 Regulation of Lpar1 8 0.45 15.31 5.05 99.84
192 INT120774 Regulation of Gene_expression of Sp6 3 0.39 0.3 0.78 99.84
193 INT172528 Positive_regulation of Gene_expression of IGFBP7 1 0.01 1.23 0.17 99.84
194 INT345113 Regulation of Lpar3 1 0.22 1.04 0.19 99.84
195 INT1275 Gene_expression of AKR1C2 1 0.75 2.92 0.16 99.84
196 INT262963 Negative_regulation of PAX6 4 0.59 4.92 0.04 99.84
197 INT178546 Negative_regulation of Gene_expression of AKR1C2 1 0.42 0.41 0 99.84
198 INT11313 Positive_regulation of Il6 526 0.70 331.27 201.59 99.82
199 INT5940 Negative_regulation of Avp 236 0.59 67.86 101.2 99.82
200 INT19 Regulation of Gnrhr 131 0.62 36.4 55.66 99.82
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