D:Respiratory Tract Infection

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Disease Term
Synonyms Infection Respiratory, Infection Respiratory Tract, Infection Upper Respiratory, Infections Respiratory, Infections Respiratory Tract, INFECTIONS UPPER RESPIRATORY, Respiratory Infection, RESPIRATORY INFECTION UPPER, Respiratory Infections, Respiratory Infections Upper, RESPIRATORY TRACT INFECTIONS
Documents 97
Hot Single Events 39
Hot Interactions 3

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Respiratory Tract Infection. They are ordered first by their relevance to Respiratory Tract Infection and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT52955 Binding of Slc6a3 and Pdpn 1 0.17 1.11 1.22 100.00
2 INT73311 Binding of Oprm1 and Pdpn 1 0.08 0.71 1.06 100.00
3 INT52954 Binding of Pdpn and Flvcr2 1 0.05 0.42 0.41 100.00
4 INT99292 Pth Positive_regulation of Jun 1 0.10 0.13 0.36 77.96
5 INT164476 Negative_regulation of Binding of Bche and Frl 1 0.02 0.48 0.51 50.96
6 INT164475 Binding of Bche and Frl 1 0.02 0.48 0.51 50.96
7 INT317959 Negative_regulation of Ephb1 Negative_regulation of Cldn4 1 0.10 0.27 0.03 5.00
8 INT317961 Negative_regulation of Ephb1 Negative_regulation of Negative_regulation of Cldn4 1 0.10 0.27 0.03 5.00
9 INT317955 Negative_regulation of Ephb1 Negative_regulation of Tecr 1 0.08 0.28 0.03 5.00
10 INT317960 Negative_regulation of Ephb1 Positive_regulation of Gene_expression of Tecr 1 0.15 0.08 0 5.00
11 INT317956 Mapk8 Positive_regulation of Gene_expression of Tecr 1 0.07 0.08 0 5.00
12 INT317957 Mapk8 Negative_regulation of Gene_expression of Cldn18 1 0.06 0.08 0 5.00
13 INT317962 Negative_regulation of Ephb1 Positive_regulation of Tecr 1 0.11 0.08 0 5.00
14 INT317958 Negative_regulation of Mapk8 Positive_regulation of Tecr 1 0.08 0.08 0 5.00
15 INT317963 Negative_regulation of Mapk8 Positive_regulation of Gene_expression of Tecr 1 0.08 0.08 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Respiratory Tract Infection. They are ordered first by their pain relevance and then by number of times they were reported in Respiratory Tract Infection. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT52952 Binding of Pdpn 8 0.13 3.57 4.79 100.00
2 INT52951 Negative_regulation of Binding of Pdpn 1 0.16 0.63 0.66 100.00
3 INT57735 Negative_regulation of Binding of LEPREL4 1 0.05 0.29 0.55 100.00
4 INT57736 Binding of LEPREL4 1 0.04 0.29 0.55 100.00
5 INT57737 Negative_regulation of LEPREL4 1 0.05 0.29 0.55 100.00
6 INT4637 Binding of Adarb1 132 0.41 14.48 67.76 100.00
7 INT178053 Positive_regulation of STIP1 7 0.44 5.09 0.11 99.60
8 INT6042 Binding of Oprm1 248 0.48 31.77 154.34 99.34
9 INT29105 Positive_regulation of OPRK1 68 0.70 7.06 44.69 99.00
10 INT47742 Binding of Flvcr2 26 0.42 3.28 15.87 98.84
11 INT203646 Gene_expression of STIP1 26 0.63 23.57 1.14 98.74
12 INT6406 Binding of Oprm1 280 0.48 40.54 226.26 98.56
13 INT57253 Negative_regulation of Binding of Oprm1 24 0.43 5.27 22.67 98.56
14 INT30386 Negative_regulation of OPRD1 33 0.52 4.34 23.06 98.28
15 INT12602 Negative_regulation of Oprm1 190 0.59 36.11 177.85 98.24
16 INT47741 Negative_regulation of Flvcr2 43 0.51 5.72 23.37 97.84
17 INT56122 Positive_regulation of Abcc3 7 0.47 2.25 4.9 97.16
18 INT71634 Gene_expression of SLC6A3 45 0.78 13.48 15.23 95.72
19 INT11279 Positive_regulation of Penk 65 0.70 18.72 30.29 95.44
20 INT5851 Positive_regulation of Gene_expression of Penk 52 0.70 14.57 25.05 95.44
21 INT17825 Gene_expression of Flvcr2 44 0.68 12.58 28.08 95.36
22 INT111056 Negative_regulation of Gene_expression of Flvcr2 9 0.13 4.15 7.18 95.36
23 INT6165 Gene_expression of Adarb1 85 0.58 18.39 51.03 95.26
24 INT5852 Gene_expression of Penk 167 0.78 44.44 71.13 94.96
25 INT1614 Gene_expression of Oprl1 164 0.78 31.43 127.74 94.92
26 INT720 Positive_regulation of POMC 807 0.70 237.37 353.83 94.88
27 INT57734 Binding of SLC6A4 36 0.48 11.94 15.42 94.64
28 INT152064 Negative_regulation of Binding of Sert1 2 0.51 1.36 0.68 92.96
29 INT55185 Binding of Sert1 26 0.48 4.43 7.57 92.48
30 INT97583 Negative_regulation of PILRB 1 0.01 0.26 0.56 88.32
31 INT55284 Regulation of CTPP 3 0.60 1.07 1.31 88.32
32 INT164474 Gene_expression of Frl 1 0.04 1.13 1.49 86.08
33 INT164477 Gene_expression of FSTL1 1 0.00 0.57 0.75 86.08
34 INT49975 Binding of SLC6A3 34 0.47 9.86 12.41 84.88
35 INT131344 Binding of CIT 1 0.16 0.16 0.98 84.64
36 INT201131 Localization of QRFPR 1 0.24 0.9 0.08 83.56
37 INT62570 Binding of Pth 48 0.48 26.45 4.85 81.44
38 INT5593 Positive_regulation of Gene_expression of Pdyn 114 0.70 29.1 74.46 81.12
39 INT5597 Gene_expression of Pdyn 433 0.78 62.97 235.47 81.12
40 INT97584 Regulation of PILRB 2 0.03 0.73 0.62 78.88
41 INT5931 Regulation of Oprm1 149 0.62 18.15 125.93 78.48
42 INT26472 Regulation of Oprm1 191 0.62 35.84 173.1 78.44
43 INT20976 Binding of CRYGS 39 0.46 5.4 20.09 76.88
44 INT2758 Binding of Dbp 36 0.44 8.3 14.47 75.68
45 INT2650 Positive_regulation of Slc3a1 50 0.57 2.95 27.52 75.04
46 INT15091 Gene_expression of SLC6A4 101 0.78 29.91 53.64 72.04
47 INT99291 Transcription of Slc6a4 7 0.46 1.16 3.28 71.84
48 INT62154 Gene_expression of Datd 8 0.67 1.28 3.91 70.08
49 INT5690 Negative_regulation of Binding of Oprd1 36 0.59 8.29 24.52 69.84
50 INT5660 Binding of Oprd1 477 0.48 71.86 342.06 69.44
51 INT70173 Gene_expression of SLC6A2 6 0.65 5.26 1.76 68.56
52 INT204081 Positive_regulation of Gene_expression of PTPLA 1 0.02 0.67 0 67.88
53 INT3359 Regulation of YY1 32 0.60 8.19 19.2 67.36
54 INT32107 Gene_expression of PTPLA 14 0.47 8.06 6.76 67.12
55 INT117710 Binding of Slc12a2 4 0.19 0.13 1.48 66.76
56 INT91360 Negative_regulation of Slc12a2 16 0.54 10.46 12.89 66.76
57 INT9355 Binding of pcp 81 0.46 10.41 24.22 64.52
58 INT124930 Positive_regulation of Binding of SLC6A4 1 0.40 0.06 0.33 62.60
59 INT131346 Negative_regulation of CIT 1 0.19 0.06 0.55 60.08
60 INT20551 Negative_regulation of COL2A1 31 0.55 21.98 2.66 58.80
61 INT158998 Negative_regulation of PTPLA 4 0.41 4.33 0 58.16
62 INT76743 Gene_expression of Slc6a4 55 0.76 13.53 24.9 57.60
63 INT7090 Gene_expression of pcp 50 0.66 13.54 8.96 56.12
64 INT201132 Gene_expression of QRFPR 1 0.23 1.77 0.11 54.56
65 INT156794 Gene_expression of CISH 41 0.58 23.09 5.03 48.40
66 INT131345 Negative_regulation of C1orf172 1 0.00 0 0.4 48.24
67 INT131342 Negative_regulation of Y95m1f5 1 0.00 0 0.4 48.24
68 INT124929 Gene_expression of ZNF74 1 0.04 0 0.2 45.36
69 INT11659 Gene_expression of COL2A1 164 0.78 78.49 22.58 44.92
70 INT796 Gene_expression of Penk 1902 0.78 275.47 1057.59 43.76
71 INT143398 Regulation of ELL 2 0.44 2.17 0.59 38.80
72 INT65081 Binding of TPM3 9 0.35 0.62 2.58 34.52
73 INT17110 Gene_expression of PSMD1 60 0.65 19.57 4.69 23.28
74 INT186995 Gene_expression of RBFOX3 17 0.30 2.31 1.3 7.60
75 INT230963 Positive_regulation of Gene_expression of RBFOX3 2 0.11 0.3 0.64 7.60
76 INT63932 Positive_regulation of Ephb1 537 0.70 259.67 296.14 5.00
77 INT9158 Gene_expression of Tnf 722 0.78 522.01 277.68 5.00
78 INT16868 Gene_expression of Il6 807 0.78 499.48 256.57 5.00
79 INT798 Positive_regulation of Gene_expression of Penk 394 0.70 78.53 203.07 5.00
80 INT11313 Positive_regulation of Il6 526 0.70 331.27 201.59 5.00
81 INT63934 Phosphorylation of Ephb1 377 0.82 150.52 188.66 5.00
82 INT94952 Positive_regulation of Mapk14 305 0.70 197.83 186.61 5.00
83 INT170025 Gene_expression of Fig4 588 0.67 183.27 113.32 5.00
84 INT48923 Gene_expression of Ephb1 211 0.77 106.23 109.9 5.00
85 INT97701 Phosphorylation of Mapk14 191 0.82 115.33 100.46 5.00
86 INT10534 Positive_regulation of Trib3 209 0.60 78.75 81.48 5.00
87 INT63936 Positive_regulation of Phosphorylation of Ephb1 131 0.70 49.38 73.16 5.00
88 INT217 Negative_regulation of Th 134 0.59 26.83 62.63 5.00
89 INT48891 Positive_regulation of Il10 143 0.70 101.42 56.72 5.00
90 INT52800 Negative_regulation of Gene_expression of Tnf 142 0.59 92.27 55.47 5.00
91 INT84495 Positive_regulation of Positive_regulation of Ephb1 85 0.70 46.12 54.11 5.00
92 INT50405 Negative_regulation of CYP3A4 238 0.59 53.65 51.51 5.00
93 INT48920 Negative_regulation of Ephb1 107 0.57 43.6 51.02 5.00
94 INT170646 Negative_regulation of Fig4 213 0.37 81.29 46.92 5.00
95 INT48929 Regulation of Ephb1 71 0.62 24.42 42.11 5.00
96 INT84260 Positive_regulation of Mapk8 124 0.69 72.84 35.98 5.00
97 INT95734 Phosphorylation of Mapk8 108 0.82 49.92 33.52 5.00
98 INT56290 Negative_regulation of Gene_expression of Il6 79 0.59 47.98 31.07 5.00
99 INT177581 Regulation of Fig4 113 0.41 39.26 27.75 5.00
100 INT5135 Negative_regulation of GNRH1 106 0.58 36.63 27.71 5.00
101 INT12129 Gene_expression of CYP3A4 107 0.78 23.11 27.6 5.00
102 INT13334 Gene_expression of Drd1a 43 0.62 7.73 24.43 5.00
103 INT4781 Gene_expression of TH 68 0.73 26.92 24.01 5.00
104 INT99068 Gene_expression of Mapk8 62 0.78 33.57 21.25 5.00
105 INT50579 Binding of CYP3A4 84 0.48 17.52 17.45 5.00
106 INT104493 Negative_regulation of Mapk8 56 0.53 27.76 16.86 5.00
107 INT128921 Negative_regulation of Gene_expression of Ephb1 18 0.49 9.54 14.93 5.00
108 INT95738 Positive_regulation of Phosphorylation of Mapk8 40 0.70 23.46 13.88 5.00
109 INT174844 Binding of Fig4 81 0.41 18.03 12.87 5.00
110 INT11307 Negative_regulation of pcp 30 0.48 7.86 11.53 5.00
111 INT163054 Gene_expression of Msn 20 0.66 0.6 9.06 5.00
112 INT111998 Positive_regulation of Positive_regulation of Mapk8 23 0.69 9.33 8.97 5.00
113 INT22771 Positive_regulation of Egf 44 0.70 16.45 8.64 5.00
114 INT127853 Localization of Ephb1 20 0.74 5.47 7.96 5.00
115 INT14166 Positive_regulation of Ahr 32 0.61 20.78 7.47 5.00
116 INT49136 Gene_expression of Ptgdr 16 0.67 1.66 7.05 5.00
117 INT122896 Negative_regulation of TH 23 0.57 9.27 6.88 5.00
118 INT17997 Positive_regulation of Mch 23 0.49 12.71 6.67 5.00
119 INT3506 Localization of TH 12 0.81 0.78 6.66 5.00
120 INT163052 Regulation of Msn 11 0.38 1.21 6.31 5.00
121 INT188844 Gene_expression of AES 44 0.58 33.94 5.85 5.00
122 INT60032 Negative_regulation of Pla2g2a 29 0.58 12.42 5.75 5.00
123 INT30317 Regulation of TH 14 0.43 7.27 5.38 5.00
124 INT128922 Negative_regulation of Gene_expression of Mapk8 6 0.34 3.93 5.36 5.00
125 INT70980 Negative_regulation of Scnn1g 8 0.23 3.11 5.31 5.00
126 INT201130 Localization of AES 31 0.63 25.45 5.12 5.00
127 INT105284 Gene_expression of Ocln 39 0.78 14.98 5.08 5.00
128 INT21901 Negative_regulation of Egf 25 0.58 10.46 4.99 5.00
129 INT105289 Gene_expression of Tjp1 28 0.76 11.72 4.67 5.00
130 INT139894 Negative_regulation of Msn 11 0.41 0.36 4.52 5.00
131 INT208287 Binding of Msn 10 0.41 0.33 4.31 5.00
132 INT13333 Regulation of Gene_expression of Drd1a 8 0.36 3.37 4.28 5.00
133 INT14165 Negative_regulation of Ahr 14 0.51 8.35 4.17 5.00
134 INT195187 Positive_regulation of Msn 5 0.49 0.38 3.66 5.00
135 INT5603 Regulation of Ptgdr 5 0.45 0.06 3.55 5.00
136 INT16966 Positive_regulation of CRS 23 0.60 22.5 3.49 5.00
137 INT110245 Gene_expression of SNCA 11 0.77 8.29 3.36 5.00
138 INT55002 Gene_expression of ASAP1 46 0.64 22.8 3.2 5.00
139 INT13335 Negative_regulation of Gene_expression of Drd1a 6 0.34 0.8 3.16 5.00
140 INT164633 Gene_expression of EGFL7 23 0.53 10.46 3.1 5.00
141 INT550 Negative_regulation of LDLR 66 0.43 44.71 3.04 5.00
142 INT4782 Positive_regulation of Gene_expression of TH 12 0.47 7.36 2.95 5.00
143 INT22875 Regulation of CRS 16 0.39 14.33 2.69 5.00
144 INT96693 Binding of COL2A1 45 0.46 37.11 2.61 5.00
145 INT166490 Localization of Msn 9 0.80 0.61 2.32 5.00
146 INT191221 Positive_regulation of Amigo2 20 0.12 24.24 2.31 5.00
147 INT56375 Positive_regulation of AMBP 25 0.60 21.24 2.22 5.00
148 INT205216 Gene_expression of Cldn4 47 0.53 9.47 2.08 5.00
149 INT74542 Negative_regulation of Tecr 8 0.55 0.86 1.96 5.00
150 INT45167 Positive_regulation of ASAP1 32 0.60 17.09 1.84 5.00
151 INT124077 Negative_regulation of Ocln 13 0.57 8.62 1.8 5.00
152 INT148266 Positive_regulation of SNCA 5 0.67 3.17 1.74 5.00
153 INT82918 Binding of AMBP 23 0.39 23.31 1.71 5.00
154 INT19747 Regulation of Egf 14 0.46 4.67 1.68 5.00
155 INT114525 Negative_regulation of Positive_regulation of Egf 4 0.35 2.93 1.5 5.00
156 INT7289 Transcription of Ptgdr 3 0.53 0.15 1.47 5.00
157 INT195185 Regulation of Regulation of Msn 3 0.38 0.29 1.46 5.00
158 INT74543 Regulation of Tecr 5 0.26 0.29 1.41 5.00
159 INT94572 Negative_regulation of Pik3c3 5 0.13 1.37 1.41 5.00
160 INT105286 Negative_regulation of Gene_expression of Ocln 7 0.31 2.52 1.35 5.00
161 INT92941 Binding of ASAP1 24 0.39 12.38 1.25 5.00
162 INT29693 Binding of Ahr 11 0.31 13.27 1.23 5.00
163 INT71629 Negative_regulation of Swd1 6 0.15 1.42 1.1 5.00
164 INT105285 Regulation of Gene_expression of Tjp1 6 0.26 2.73 1.08 5.00
165 INT125904 Positive_regulation of Ocln 6 0.45 2.06 1.06 5.00
166 INT125960 Gene_expression of Ptprs 8 0.78 2.87 0.99 5.00
167 INT240461 Regulation of Negative_regulation of Ephb1 4 0.37 1.66 0.96 5.00
168 INT208792 Negative_regulation of Gene_expression of TH 6 0.35 1.11 0.94 5.00
169 INT182851 Localization of AAVS1 7 0.78 0.77 0.87 5.00
170 INT200900 Localization of Mapk8 9 0.40 5.76 0.84 5.00
171 INT296768 Negative_regulation of RBFOX3 3 0.25 0.87 0.84 5.00
172 INT205213 Positive_regulation of Gene_expression of Cldn4 12 0.47 3.37 0.8 5.00
173 INT65286 Binding of ARIH1 10 0.48 4.3 0.76 5.00
174 INT164632 Positive_regulation of EGFL7 8 0.32 3.03 0.71 5.00
175 INT34599 Binding of TST 7 0.32 3.88 0.71 5.00
176 INT55003 Regulation of Gene_expression of ASAP1 2 0.39 0 0.64 5.00
177 INT280866 Negative_regulation of Transcription of Ptgdr 1 0.06 0 0.6 5.00
178 INT158898 Positive_regulation of Gene_expression of Ocln 5 0.22 2.06 0.57 5.00
179 INT84978 Positive_regulation of CHDH 21 0.50 21.97 0.48 5.00
180 INT304644 Positive_regulation of Tecr 2 0.31 0.45 0.43 5.00
181 INT343969 Negative_regulation of Localization of AAVS1 1 0.12 0.33 0.41 5.00
182 INT343972 Negative_regulation of Binding of SNCA 1 0.36 0.2 0.39 5.00
183 INT280865 Positive_regulation of Protein_catabolism of Msn 1 0.35 0 0.38 5.00
184 INT74546 Positive_regulation of Gene_expression of Tecr 2 0.47 0.16 0.37 5.00
185 INT74547 Gene_expression of Tecr 2 0.64 0.41 0.37 5.00
186 INT169628 Binding of SNCA 4 0.47 3.53 0.36 5.00
187 INT165400 Positive_regulation of TST 13 0.68 4.25 0.35 5.00
188 INT280863 Protein_catabolism of Msn 1 0.62 0 0.35 5.00
189 INT343970 Regulation of ZAK 1 0.07 0.14 0.34 5.00
190 INT124076 Binding of Ocln 3 0.37 1.01 0.34 5.00
191 INT280862 Positive_regulation of Localization of Msn 1 0.35 0 0.3 5.00
192 INT343973 Localization of SNCA 1 0.63 0.07 0.3 5.00
193 INT179917 Negative_regulation of Negative_regulation of Ephb1 2 0.25 1.17 0.28 5.00
194 INT343976 Negative_regulation of Negative_regulation of TH 1 0.23 0.19 0.23 5.00
195 INT343975 Negative_regulation of SNAPC1 1 0.00 0.12 0.22 5.00
196 INT130125 Regulation of Ocln 5 0.44 0.87 0.19 5.00
197 INT201127 Positive_regulation of QRFPR 1 0.21 0.59 0.18 5.00
198 INT317945 Gene_expression of Cldn18 1 0.23 0.59 0.17 5.00
199 INT280867 Regulation of Positive_regulation of Msn 1 0.19 0.05 0.17 5.00
200 INT317940 Negative_regulation of Gene_expression of Cldn18 1 0.11 0.31 0.17 5.00
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