D:Restenosis

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Disease Term
Synonyms Coronary Restenoses, Coronary Restenosis, RESTENOSES CORONARY, Restenosis Coronary
Documents 48
Hot Single Events 32
Hot Interactions 1

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Restenosis. They are ordered first by their relevance to Restenosis and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT115006 Binding of Serpine1 and Cpb2 1 0.09 1.53 0.2 100.00
2 INT308314 Binding of CD34 and Pfpl 1 0.03 0.57 0 60.32
3 INT225158 Binding of CDK2 and CDKN1A 7 0.30 3.26 1.02 5.00
4 INT72445 Binding of AGT and REN 3 0.34 0.88 0.31 5.00
5 INT258017 Binding of AGT and ANGPT2 3 0.11 2.35 0.19 5.00
6 INT258016 AGTR1 Positive_regulation of EGFR 1 0.15 1.24 0.13 5.00
7 INT258014 Binding of ANGPT2 and RASGRP1 1 0.00 1.58 0.1 5.00
8 INT258018 Binding of AGT and RASGRP1 1 0.00 1.59 0.1 5.00
9 INT258021 Positive_regulation of Binding of CDK2 and CDKN1A 1 0.11 0.84 0.07 5.00
10 INT258015 Binding of ANGPT2 and REN 1 0.01 0.59 0.05 5.00
11 INT258012 ANGPT2 Positive_regulation of Binding of AGTR1 and ANGPT2 1 0.00 0.29 0.04 5.00
12 INT258020 Binding of AGTR1 and ANGPT2 1 0.03 0.29 0.04 5.00
13 INT268217 Gopc Positive_regulation of Gene_expression of Ang2 1 0.03 2.28 0.03 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Restenosis. They are ordered first by their pain relevance and then by number of times they were reported in Restenosis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT17056 Gene_expression of DLD 37 0.57 13.15 5.47 100.00
2 INT93343 Gene_expression of Cpb2 10 0.58 4.63 3.24 99.12
3 INT83193 Binding of Olr1 6 0.42 10 2.43 98.88
4 INT15918 Gene_expression of Serpine1 60 0.62 41.73 7.72 98.84
5 INT83190 Gene_expression of Olr1 26 0.59 12.47 2.91 98.60
6 INT167381 Localization of DES 4 0.73 4.15 0.77 98.58
7 INT205618 Gene_expression of Renbp 15 0.26 9.26 1.04 98.22
8 INT296403 Regulation of Positive_regulation of Renbp 1 0.03 1.31 0 96.36
9 INT197143 Positive_regulation of Renbp 15 0.33 9.41 1.31 95.64
10 INT11063 Negative_regulation of CES1 16 0.53 6.92 1.11 95.16
11 INT66857 Regulation of CCL2 39 0.53 28.55 18.35 94.72
12 INT55879 Gene_expression of CCL2 421 0.78 240.74 166.02 94.72
13 INT55878 Regulation of Gene_expression of CCL2 34 0.62 15.71 17.97 94.72
14 INT107585 Gene_expression of CCR2 35 0.71 26.44 14.75 94.04
15 INT148839 Regulation of Gene_expression of CCR2 2 0.26 1.78 0.76 94.04
16 INT277981 Negative_regulation of Pfpl 3 0.03 1.75 0.05 93.98
17 INT83194 Binding of APOH 4 0.17 3.92 0.66 92.88
18 INT83192 Binding of Apoh 1 0.00 1.74 0.61 92.88
19 INT83191 Regulation of Binding of Apoh 1 0.00 0.88 0.31 92.88
20 INT83195 Regulation of Binding of APOH 1 0.13 0.88 0.31 92.88
21 INT22454 Regulation of Crp 213 0.62 160.67 49.24 91.48
22 INT93944 Regulation of FCER2 3 0.40 0.8 0.36 91.48
23 INT50387 Negative_regulation of AR 67 0.45 26.31 6.61 90.72
24 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 82.84
25 INT15516 Gene_expression of Crp 711 0.77 615.33 173.09 82.64
26 INT3375 Gene_expression of IGHE 535 0.77 387.47 65.46 82.64
27 INT104733 Positive_regulation of Gene_expression of Ren1 24 0.67 43.87 2.47 82.60
28 INT44163 Gene_expression of Ren1 69 0.78 97.75 6.27 82.28
29 INT151904 Binding of Ager 4 0.18 8.07 0.6 82.08
30 INT174106 Binding of Renbp 18 0.24 15.82 0.58 81.60
31 INT105974 Positive_regulation of PRKAB1 43 0.67 23.47 4.16 80.48
32 INT212415 Positive_regulation of Positive_regulation of PRKAB1 4 0.36 2.63 0.37 80.48
33 INT152262 Positive_regulation of FASN 3 0.32 1.22 0.09 78.40
34 INT61626 Transcription of IL6 73 0.72 42.04 17.86 78.00
35 INT68099 Positive_regulation of Agtr2 21 0.48 16.63 4.07 76.76
36 INT268213 Positive_regulation of Ang2 8 0.08 18.88 0.58 76.76
37 INT268208 Transcription of Agtr2 1 0.05 3.15 0.17 76.36
38 INT67981 Positive_regulation of CCL2 165 0.70 136.84 61.85 75.92
39 INT268216 Transcription of Ang2 1 0.06 5.28 0.17 75.72
40 INT98784 Gene_expression of Ccnb1 11 0.59 4.53 0.75 75.00
41 INT24643 Gene_expression of Hdlcl1 30 0.73 26.83 1.9 74.44
42 INT53447 Negative_regulation of DLD 17 0.54 12.9 2.48 72.88
43 INT120067 Positive_regulation of Gene_expression of CCR2 10 0.46 5.13 3.02 71.80
44 INT101700 Binding of Ang2 6 0.18 8.34 1.48 67.28
45 INT133647 Negative_regulation of HDAC9 149 0.57 106.84 17.9 63.60
46 INT21682 Binding of CD34 18 0.47 13.19 1.47 60.32
47 INT217928 Binding of Pfpl 2 0.19 0.52 0 59.44
48 INT96850 Negative_regulation of CCL2 42 0.59 24.89 12.55 57.80
49 INT308313 Regulation of Pfpl 1 0.03 0.6 0.04 57.04
50 INT55880 Negative_regulation of Gene_expression of CCL2 49 0.59 22.37 18.09 53.60
51 INT230806 Positive_regulation of Gene_expression of Agt 11 0.55 16.08 0.83 51.64
52 INT148071 Gene_expression of Agt 42 0.74 44.9 2.43 50.20
53 INT10706 Regulation of Il6 150 0.62 93.23 62.34 50.00
54 INT56448 Regulation of ICAM1 52 0.60 55.1 10.96 50.00
55 INT62895 Gene_expression of NOSTRIN 51 0.75 28.8 10.68 50.00
56 INT111594 Positive_regulation of Gene_expression of NOSTRIN 20 0.32 8.69 5 50.00
57 INT67985 Regulation of Saa 9 0.44 9.36 3 50.00
58 INT173116 Regulation of VCAM1 14 0.33 11.85 1.92 50.00
59 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98 42.48
60 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 41.64
61 INT81688 Binding of ras 32 0.41 30.13 4.02 32.68
62 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 25.44
63 INT136280 Transcription of GAPDH 5 0.67 1.13 0.28 10.36
64 INT9659 Gene_expression of Il6 991 0.78 715.11 265.57 5.00
65 INT120811 Gene_expression of Gopc 1174 0.59 428.49 150.55 5.00
66 INT812 Localization of INS 1026 0.81 515.6 145.31 5.00
67 INT86024 Gene_expression of PPARA 736 0.78 497.93 91.14 5.00
68 INT71789 Positive_regulation of MAPK1 396 0.70 234.44 89.27 5.00
69 INT1724 Negative_regulation of ACE 437 0.59 315.64 74.48 5.00
70 INT822 Gene_expression of ESR1 529 0.78 302.16 63.64 5.00
71 INT67614 Positive_regulation of PPARA 438 0.68 293.28 63.61 5.00
72 INT9657 Positive_regulation of Gene_expression of Il6 237 0.70 180.45 63.6 5.00
73 INT18981 Gene_expression of ABAT 78 0.68 38.35 61.36 5.00
74 INT1536 Negative_regulation of NA 244 0.55 52.67 59.79 5.00
75 INT169926 Positive_regulation of Gopc 416 0.46 157.8 58.67 5.00
76 INT1199 Positive_regulation of INS 579 0.70 399.64 50.43 5.00
77 INT48718 Positive_regulation of PRKCA 109 0.69 36.16 46.49 5.00
78 INT71786 Phosphorylation of MAPK1 256 0.82 110.09 46.17 5.00
79 INT1322 Positive_regulation of Localization of INS 293 0.70 120.86 45.98 5.00
80 INT170054 Negative_regulation of Gopc 280 0.38 117.89 42.4 5.00
81 INT3252 Negative_regulation of INS 428 0.59 271.65 39.52 5.00
82 INT103094 Binding of PPARA 308 0.47 177.26 34.75 5.00
83 INT3913 Positive_regulation of ABAT 47 0.69 22.73 33.4 5.00
84 INT56072 Negative_regulation of NFKB1 94 0.59 53.16 28.19 5.00
85 INT21687 Positive_regulation of ras 143 0.58 97.34 27.31 5.00
86 INT11159 Gene_expression of EGFR 698 0.78 548.93 25.69 5.00
87 INT825 Negative_regulation of ADRA1D 54 0.58 20.25 22.78 5.00
88 INT3330 Gene_expression of AGT 149 0.76 98.65 22.73 5.00
89 INT3299 Positive_regulation of AGT 126 0.68 79.45 21.91 5.00
90 INT96269 Positive_regulation of Mcpt1 71 0.61 52.38 20.4 5.00
91 INT1756 Negative_regulation of DNAH8 105 0.59 42.73 20.24 5.00
92 INT23533 Gene_expression of CA2 110 0.75 30.81 19.4 5.00
93 INT70614 Gene_expression of FAS 118 0.75 112.33 19.01 5.00
94 INT28215 Gene_expression of CDKN1A 196 0.76 113.9 18.3 5.00
95 INT6791 Binding of NA 55 0.46 5.36 17.59 5.00
96 INT29555 Positive_regulation of CALM1 58 0.69 14.09 17.37 5.00
97 INT13510 Gene_expression of ERBB2 530 0.78 405.68 16.79 5.00
98 INT65659 Positive_regulation of STAT3 132 0.70 69.56 15.95 5.00
99 INT9783 Gene_expression of INSRR 81 0.50 32.99 15.52 5.00
100 INT170335 Gene_expression of INCENP 176 0.54 91.62 15.31 5.00
101 INT34952 Regulation of ABAT 28 0.61 6.05 14.39 5.00
102 INT42979 Positive_regulation of INSRR 47 0.32 12.24 14.38 5.00
103 INT20665 Gene_expression of ACE 87 0.78 51.71 14.19 5.00
104 INT80688 Positive_regulation of Positive_regulation of MAPK1 72 0.69 39.35 14.11 5.00
105 INT62441 Gene_expression of ABCC1 56 0.78 21.01 12.93 5.00
106 INT661 Gene_expression of REN 100 0.78 48.21 11.36 5.00
107 INT8065 Binding of AGT 54 0.48 20.54 10.85 5.00
108 INT36453 Binding of ABCA1 48 0.45 19.9 10.84 5.00
109 INT79656 Positive_regulation of NR3C1 14 0.68 6.38 10.83 5.00
110 INT13499 Gene_expression of Agtr2 68 0.76 35.64 10.59 5.00
111 INT173159 Localization of PPARA 96 0.74 64.55 10.26 5.00
112 INT98130 Positive_regulation of CASP8 79 0.67 65.29 10.08 5.00
113 INT3846 Positive_regulation of GSR 60 0.50 35.16 9.37 5.00
114 INT28312 Gene_expression of ABCA1 85 0.72 37.69 9.27 5.00
115 INT92777 Positive_regulation of Gene_expression of ABAT 13 0.44 7.49 9.27 5.00
116 INT20664 Binding of ACE 60 0.48 35.27 9.16 5.00
117 INT177831 Gene_expression of HDAC1 24 0.65 21.37 8.37 5.00
118 INT53487 Gene_expression of TSC1 81 0.58 77.71 7.94 5.00
119 INT21685 Gene_expression of ras 115 0.66 85.6 7.76 5.00
120 INT96994 Phosphorylation of EGFR 99 0.82 52.75 7.33 5.00
121 INT83006 Gene_expression of AGTR1 59 0.75 54.46 7.27 5.00
122 INT47994 Negative_regulation of Lipg 45 0.50 27.19 7.24 5.00
123 INT102814 Negative_regulation of CASP3 46 0.43 28.54 6.94 5.00
124 INT84685 Regulation of BCL2 67 0.60 72.96 6.65 5.00
125 INT15775 Positive_regulation of Ren1 50 0.69 22.38 6.19 5.00
126 INT5490 Binding of CA2 52 0.36 9.73 5.53 5.00
127 INT21609 Positive_regulation of RASGRP1 58 0.50 40.78 5.47 5.00
128 INT97145 Positive_regulation of TBK1 14 0.12 15.32 5.43 5.00
129 INT95120 Positive_regulation of CASP9 76 0.67 67.55 5.33 5.00
130 INT102891 Positive_regulation of AGTR1 31 0.67 30.57 5.29 5.00
131 INT60585 Regulation of TP53 59 0.59 54.55 5.21 5.00
132 INT107386 Negative_regulation of AGTR1 37 0.55 35.94 5.15 5.00
133 INT58766 Gene_expression of ANGPT2 41 0.67 21.65 4.82 5.00
134 INT3332 Protein_catabolism of AGT 23 0.87 3.17 4.39 5.00
135 INT85126 Negative_regulation of MAP2K6 19 0.39 12.12 4.39 5.00
136 INT125282 Negative_regulation of Positive_regulation of NR3C1 3 0.57 0.54 4.31 5.00
137 INT21686 Positive_regulation of Gene_expression of ras 19 0.42 13.79 4.28 5.00
138 INT10374 Gene_expression of RARA 39 0.75 22.59 4.28 5.00
139 INT88414 Negative_regulation of CDK2 30 0.57 18.4 3.96 5.00
140 INT28673 Gene_expression of APOB 51 0.73 34.02 3.95 5.00
141 INT103350 Gene_expression of DNMT1 15 0.67 9.77 3.83 5.00
142 INT1722 Protein_catabolism of ACE 10 0.88 2.61 3.76 5.00
143 INT73463 Positive_regulation of Gene_expression of TSC1 20 0.38 14.59 3.53 5.00
144 INT163832 Negative_regulation of Gene_expression of EGFR 50 0.59 39.71 3.45 5.00
145 INT87517 Gene_expression of LDLR 73 0.69 37.35 3.32 5.00
146 INT550 Negative_regulation of LDLR 66 0.43 44.71 3.04 5.00
147 INT41545 Negative_regulation of APRT 8 0.57 2.99 2.88 5.00
148 INT258081 Protein_catabolism of ABAT 5 0.10 2.57 2.86 5.00
149 INT113149 Gene_expression of Tmprss11d 15 0.75 8.51 2.72 5.00
150 INT19177 Negative_regulation of GRHPR 19 0.53 12.65 2.71 5.00
151 INT221097 Negative_regulation of Atp8a1 15 0.57 10.52 2.65 5.00
152 INT92141 Negative_regulation of CDKN2A 53 0.57 44.23 2.48 5.00
153 INT27988 Negative_regulation of Positive_regulation of AGT 11 0.42 5.71 2.27 5.00
154 INT112364 Negative_regulation of HIF1A 22 0.57 16.95 2.13 5.00
155 INT153718 Gene_expression of ANGPT1 15 0.45 10.82 2.13 5.00
156 INT29393 Positive_regulation of APRT 18 0.67 5.28 2.13 5.00
157 INT17890 Negative_regulation of HMGCR 26 0.42 12.05 1.94 5.00
158 INT48792 Regulation of ERBB2 48 0.57 36.56 1.8 5.00
159 INT57018 Gene_expression of GANAB 9 0.08 3.76 1.79 5.00
160 INT173177 Positive_regulation of Localization of PPARA 21 0.49 12.61 1.74 5.00
161 INT53532 Gene_expression of Lcp1 10 0.70 11.57 1.69 5.00
162 INT118292 Negative_regulation of Phosphorylation of EGFR 27 0.59 13.62 1.54 5.00
163 INT60162 Gene_expression of Ie 41 0.58 23.77 1.52 5.00
164 INT258051 Negative_regulation of Protein_catabolism of ABAT 3 0.04 1.86 1.52 5.00
165 INT44164 Localization of Ren1 18 0.49 10.53 1.49 5.00
166 INT108556 Negative_regulation of BCL2L10 8 0.32 7.77 1.49 5.00
167 INT258048 Regulation of TBK1 4 0.05 3.81 1.44 5.00
168 INT8068 Gene_expression of RASGRP1 29 0.54 15.1 1.37 5.00
169 INT130998 Regulation of PRKAB1 11 0.45 5.7 1.33 5.00
170 INT44147 Positive_regulation of Gene_expression of Agtr2 11 0.50 9.02 1.28 5.00
171 INT128176 Regulation of RHOA 13 0.44 4.35 1.26 5.00
172 INT258053 Positive_regulation of Negative_regulation of HDAC9 8 0.27 7.37 1.23 5.00
173 INT45553 Negative_regulation of PCK1 3 0.43 0.73 1.17 5.00
174 INT108559 Gene_expression of Pol 46 0.45 30.07 1.14 5.00
175 INT149144 Gene_expression of Ang2 5 0.46 34.27 1.05 5.00
176 INT106735 Phosphorylation of CDK2 11 0.79 4.03 1.02 5.00
177 INT56972 Regulation of ANGPT2 6 0.44 3.48 0.86 5.00
178 INT58765 Positive_regulation of Gene_expression of ANGPT2 11 0.38 8.2 0.81 5.00
179 INT202683 Localization of FAS 6 0.73 5.86 0.8 5.00
180 INT149145 Positive_regulation of Gene_expression of Ang2 4 0.34 27.89 0.78 5.00
181 INT130599 Negative_regulation of PAICS 4 0.30 2.33 0.7 5.00
182 INT37544 Binding of ANGPT2 9 0.19 6.51 0.69 5.00
183 INT102174 Gene_expression of FASN 11 0.65 6.4 0.67 5.00
184 INT108558 Transcription of Pol 5 0.35 4.67 0.64 5.00
185 INT133589 Negative_regulation of Pol 6 0.25 2.84 0.61 5.00
186 INT158829 Negative_regulation of FAS 5 0.41 4.12 0.48 5.00
187 INT87406 Gene_expression of GSTP1 16 0.77 11.37 0.35 5.00
188 INT130999 Localization of PRKAB1 5 0.57 4.1 0.35 5.00
189 INT162823 Regulation of Gene_expression of Ren1 4 0.62 2.69 0.35 5.00
190 INT258059 Negative_regulation of Positive_regulation of GSR 3 0.41 1.79 0.33 5.00
191 INT258082 Negative_regulation of ABCC3 1 0.07 0.43 0.31 5.00
192 INT258080 Positive_regulation of Negative_regulation of ABCC3 1 0.06 0.44 0.31 5.00
193 INT176039 Regulation of HMGCR 6 0.17 2.32 0.29 5.00
194 INT258074 Negative_regulation of HDLBP 2 0.06 2.76 0.28 5.00
195 INT197016 Positive_regulation of Gene_expression of LDLR 13 0.50 5.82 0.24 5.00
196 INT258055 Positive_regulation of ARG1 7 0.49 3.45 0.19 5.00
197 INT147149 Transcription of CDKN2A 8 0.67 6.85 0.15 5.00
198 INT258046 Binding of DUT 1 0.01 0.63 0.15 5.00
199 INT258072 Binding of RERE 2 0.07 1.14 0.15 5.00
200 INT211384 Negative_regulation of FASN 2 0.41 1.19 0.14 5.00
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