D:Restrictive Cardiomyopathy

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pChart

Disease Term
Synonyms Cardiomyopathies Restrictive, Cardiomyopathy Restrictive, CONSTRICTIVE CARDIOMYOPATHY, Primary Restrictive Cardiomyopathy, Primary Restrictive Cardiomyopathy Disorder, Restrictive Cardiomyopathies, RESTRICTIVE CONSTRICTIVE CARDIOMYOPATHY
Documents 43
Hot Single Events 7
Hot Interactions 1

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Restrictive Cardiomyopathy. They are ordered first by their relevance to Restrictive Cardiomyopathy and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT85816 Binding of CEL and TTR 1 0.39 0.77 0.14 80.08
2 INT224922 Binding of FAP and TARM1 1 0.06 1.4 0.06 50.00
3 INT224921 Binding of TTR and TARM1 1 0.06 1.06 0 50.00
4 INT177958 IGHE Positive_regulation of TNF 1 0.03 2.23 0 48.52
5 INT177959 Positive_regulation of IGHE Positive_regulation of TNF 1 0.03 2.23 0 48.52
6 INT177961 Binding of CCR3 and CCL11 1 0.04 0.73 0.26 5.00
7 INT177957 CCL11 Regulation of Binding of IL5 and CCL11 1 0.01 0.71 0.25 5.00
8 INT177960 Binding of IL5 and CCL11 1 0.03 0.71 0.25 5.00
9 INT177962 IL4 Positive_regulation of VCAM1 1 0.02 0.97 0.2 5.00
10 INT296893 Nps Negative_regulation of Gene_expression of REN 1 0.00 1.05 0.04 5.00
11 INT214886 Binding of Atcay and FIP1L1 1 0.08 4.06 0 5.00
12 INT214885 Binding of PDGFRA and Atcay 1 0.08 4.05 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Restrictive Cardiomyopathy. They are ordered first by their pain relevance and then by number of times they were reported in Restrictive Cardiomyopathy. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT9082 Positive_regulation of ESR1 238 0.69 148.51 36.69 99.68
2 INT9550 Gene_expression of TNNI3 113 0.78 86.79 10.56 99.50
3 INT131788 Positive_regulation of NPPB 87 0.67 86.1 8.81 96.88
4 INT56342 Gene_expression of TTR 34 0.78 16.5 2.05 94.16
5 INT9801 Regulation of TTR 3 0.45 1.4 0.48 94.16
6 INT62950 Gene_expression of NPPB 73 0.75 65.91 6.54 80.56
7 INT93789 Gene_expression of Tnnc1 28 0.76 17.3 1.99 80.56
8 INT122196 Gene_expression of TAL1 5 0.47 2.07 0.63 68.96
9 INT69160 Positive_regulation of IL5 41 0.65 36.04 7.75 68.56
10 INT16068 Gene_expression of SERPINB1 27 0.60 20.51 6.56 68.32
11 INT25493 Gene_expression of TFPI 74 0.76 39.44 14.78 67.60
12 INT3550 Negative_regulation of GLA 52 0.59 33.93 5.26 67.28
13 INT46320 Negative_regulation of Ttr 4 0.15 2.54 1 66.60
14 INT822 Gene_expression of ESR1 529 0.78 302.16 63.64 66.48
15 INT192423 Positive_regulation of TARM1 5 0.34 10.77 0.51 66.32
16 INT224924 Binding of TARM1 4 0.18 3.42 0.39 66.32
17 INT44223 Positive_regulation of TTR 10 0.70 10.98 1.95 64.44
18 INT25152 Gene_expression of SAA1 37 0.75 53.56 8.07 61.44
19 INT12890 Gene_expression of Ttr 15 0.63 7.68 1.6 61.44
20 INT1724 Negative_regulation of ACE 437 0.59 315.64 74.48 52.44
21 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 49.12
22 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210 49.12
23 INT3987 Positive_regulation of IGHE 316 0.70 283.2 40.16 49.12
24 INT3988 Positive_regulation of Gene_expression of IGHE 98 0.68 91.46 9.61 49.12
25 INT3375 Gene_expression of IGHE 535 0.77 387.47 65.46 48.52
26 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 47.96
27 INT88640 Localization of TTR 5 0.75 1.71 0.3 39.52
28 INT210066 Negative_regulation of Regulation of SH3GL3 1 0.03 0.28 0.14 37.68
29 INT37485 Regulation of RAPGEF5 10 0.44 6.64 1.51 36.56
30 INT210061 Regulation of SH3GL3 6 0.20 1.81 0.5 36.56
31 INT47734 Positive_regulation of RAPGEF5 19 0.56 13.16 1.41 21.56
32 INT3758 Gene_expression of ALB 326 0.78 184.65 38.75 20.24
33 INT3952 Negative_regulation of ALB 116 0.59 72.18 18.35 20.24
34 INT30738 Negative_regulation of Gene_expression of ALB 32 0.59 19.01 5.04 20.24
35 INT156639 Localization of Hcm 5 0.64 7.65 0.16 13.52
36 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97 5.00
37 INT11587 Gene_expression of CSF2 645 0.78 544.38 93.89 5.00
38 INT5056 Gene_expression of IFNG 216 0.78 137.52 74.57 5.00
39 INT56298 Gene_expression of IL4 306 0.78 182.18 72.92 5.00
40 INT9408 Positive_regulation of Crp 296 0.69 242.27 57.35 5.00
41 INT5623 Positive_regulation of Nppa 174 0.70 69.96 52.33 5.00
42 INT6473 Positive_regulation of Gene_expression of IL1B 204 0.70 117.23 50.86 5.00
43 INT375 Positive_regulation of REN 293 0.70 152.46 47.55 5.00
44 INT63349 Gene_expression of PECAM1 199 0.75 166.03 36.76 5.00
45 INT73498 Gene_expression of IL13 117 0.44 83.85 32.26 5.00
46 INT10915 Gene_expression of ITGAM 164 0.78 92.42 29.78 5.00
47 INT69157 Gene_expression of IL5 127 0.77 102.58 26.81 5.00
48 INT5622 Gene_expression of Nppa 101 0.78 49.46 25.31 5.00
49 INT3299 Positive_regulation of AGT 126 0.68 79.45 21.91 5.00
50 INT62042 Positive_regulation of Gene_expression of IL4 67 0.56 42.05 20.39 5.00
51 INT125312 Positive_regulation of COPD 134 0.59 162.55 20.27 5.00
52 INT70970 Binding of COPD 144 0.42 180.34 18.29 5.00
53 INT25223 Positive_regulation of Gene_expression of IFNG 41 0.67 36.97 15.89 5.00
54 INT90766 Gene_expression of PCS 93 0.77 40.48 14.51 5.00
55 INT159127 Gene_expression of Nps 49 0.75 16.91 12.06 5.00
56 INT9084 Positive_regulation of Nppb 74 0.70 69.77 11.85 5.00
57 INT1190 Positive_regulation of F2 53 0.70 46.41 11.64 5.00
58 INT661 Gene_expression of REN 100 0.78 48.21 11.36 5.00
59 INT8903 Gene_expression of IFNA2 58 0.71 38.23 8.68 5.00
60 INT3757 Positive_regulation of Gene_expression of ALB 45 0.69 23.73 6.85 5.00
61 INT57562 Gene_expression of GLA 52 0.77 24.62 6.14 5.00
62 INT8803 Gene_expression of IL3 32 0.78 21.06 6.01 5.00
63 INT77955 Negative_regulation of PCS 55 0.43 39.32 5.76 5.00
64 INT69153 Positive_regulation of Gene_expression of IL5 22 0.32 23.59 5.7 5.00
65 INT103260 Positive_regulation of Nps 35 0.48 23.8 5.67 5.00
66 INT53684 Negative_regulation of Gene_expression of ITGAM 23 0.59 14.36 5.66 5.00
67 INT56299 Transcription of IL4 15 0.64 10.2 5.44 5.00
68 INT2725 Positive_regulation of FCER2 23 0.69 23.08 4.7 5.00
69 INT82354 Positive_regulation of PECAM1 25 0.34 22.93 4.69 5.00
70 INT87322 Binding of ITGAL 23 0.47 15.73 4.68 5.00
71 INT87632 Positive_regulation of Gene_expression of PECAM1 32 0.45 29.47 4.66 5.00
72 INT45159 Regulation of Nppb 16 0.54 13.57 4.46 5.00
73 INT73503 Positive_regulation of Gene_expression of IL13 16 0.37 14.6 4.23 5.00
74 INT48518 Gene_expression of ANPEP 51 0.78 22.88 4.18 5.00
75 INT172677 Gene_expression of SHE 65 0.59 25.86 3.85 5.00
76 INT40712 Gene_expression of EPX 9 0.78 5.93 3.6 5.00
77 INT159472 Localization of NPPB 32 0.79 33.67 3.59 5.00
78 INT131877 Negative_regulation of Nps 12 0.39 8.19 3.56 5.00
79 INT28802 Binding of F2 15 0.47 8.8 3.47 5.00
80 INT45272 Regulation of Nps 15 0.39 8.08 2.69 5.00
81 INT155889 Binding of Nps 22 0.42 9.79 2.6 5.00
82 INT210058 Regulation of ELF3 11 0.29 7.93 2.51 5.00
83 INT150476 Positive_regulation of ELF3 32 0.56 13.61 2.39 5.00
84 INT62511 Negative_regulation of MCS 20 0.50 6.77 2.35 5.00
85 INT27230 Gene_expression of LTBR 10 0.75 8.57 2.34 5.00
86 INT84018 Gene_expression of RNASE3 15 0.65 8.27 2.12 5.00
87 INT84264 Regulation of NPPB 22 0.61 21.18 1.94 5.00
88 INT22335 Regulation of Negative_regulation of ACE 10 0.44 7.01 1.77 5.00
89 INT40713 Negative_regulation of EPX 7 0.37 2.21 1.73 5.00
90 INT145884 Negative_regulation of SH3GL3 19 0.43 12.67 1.72 5.00
91 INT98984 Localization of RNASE3 5 0.47 4.51 1.68 5.00
92 INT163613 Transcription of CSF2 16 0.60 12.98 1.62 5.00
93 INT237862 Positive_regulation of Gene_expression of Nps 8 0.43 3.82 1.52 5.00
94 INT78704 Binding of CCL11 10 0.37 11.38 1.44 5.00
95 INT210060 Localization of SH3GL3 4 0.59 6.61 1.37 5.00
96 INT61223 Positive_regulation of Negative_regulation of ACE 6 0.49 5.92 1.37 5.00
97 INT207134 Positive_regulation of tryptase 11 0.47 11.16 1.21 5.00
98 INT170979 Transcription of IL5 7 0.33 5.08 1.21 5.00
99 INT36179 Regulation of GLA 11 0.44 6.56 1.12 5.00
100 INT188774 Binding of RAPGEF5 12 0.29 13.55 1.04 5.00
101 INT67156 Binding of ITGA4 6 0.14 2.63 1.03 5.00
102 INT79862 Negative_regulation of Gene_expression of ANPEP 3 0.38 1.67 0.98 5.00
103 INT210065 Positive_regulation of SH3GL3 8 0.45 6.45 0.96 5.00
104 INT210057 Gene_expression of SH3GL3 24 0.50 8.69 0.94 5.00
105 INT23921 Negative_regulation of NPPB 13 0.58 16.19 0.9 5.00
106 INT57560 Positive_regulation of GLA 14 0.54 5.01 0.83 5.00
107 INT119102 Gene_expression of PDGFRA 13 0.75 11.99 0.81 5.00
108 INT177965 Negative_regulation of Transcription of IL4 3 0.25 2.11 0.78 5.00
109 INT132662 Binding of Hcm 11 0.31 14.41 0.73 5.00
110 INT237866 Positive_regulation of Positive_regulation of Nps 5 0.48 2.67 0.69 5.00
111 INT177972 Transcription of IL3 2 0.20 1.81 0.66 5.00
112 INT38252 Positive_regulation of Hcm 7 0.40 9.96 0.59 5.00
113 INT157226 Positive_regulation of Gene_expression of Tnnc1 11 0.49 6.21 0.57 5.00
114 INT114519 Gene_expression of Hcm 10 0.57 13.01 0.57 5.00
115 INT177968 Negative_regulation of Transcription of CSF2 3 0.37 2.8 0.55 5.00
116 INT210064 Negative_regulation of Localization of SH3GL3 3 0.31 1.44 0.54 5.00
117 INT82051 Negative_regulation of RNASE3 8 0.32 6.81 0.53 5.00
118 INT210072 Negative_regulation of Gene_expression of SH3GL3 13 0.31 2.94 0.47 5.00
119 INT11118 Gene_expression of RAPGEF5 13 0.65 9.35 0.43 5.00
120 INT72717 Gene_expression of Nppc 8 0.51 6.25 0.39 5.00
121 INT177970 Negative_regulation of Transcription of IL5 2 0.20 1.62 0.39 5.00
122 INT210073 Regulation of Negative_regulation of SH3GL3 2 0.20 1.24 0.35 5.00
123 INT210063 Negative_regulation of Positive_regulation of SH3GL3 4 0.28 1.84 0.31 5.00
124 INT177969 Localization of PRG2 1 0.09 1.03 0.26 5.00
125 INT177967 Binding of CCR3 1 0.16 0.72 0.25 5.00
126 INT210070 Localization of GLA 1 0.70 1.96 0.24 5.00
127 INT214883 Binding of Atcay 2 0.10 1.1 0.22 5.00
128 INT210059 Negative_regulation of Localization of GLA 1 0.40 0.77 0.12 5.00
129 INT210068 Positive_regulation of Negative_regulation of SH3GL3 1 0.03 0.54 0.12 5.00
130 INT177966 Negative_regulation of Gene_expression of LTBR 1 0.08 0.38 0.12 5.00
131 INT119103 Gene_expression of FIP1L1 2 0.49 2.95 0.11 5.00
132 INT177973 Negative_regulation of Transcription of IL3 1 0.16 0.59 0.1 5.00
133 INT177971 Negative_regulation of Gene_expression of RNASE3 1 0.04 0.47 0.09 5.00
134 INT271793 Regulation of Binding of F2 1 0.03 0.46 0.05 5.00
135 INT210069 Regulation of Gene_expression of SH3GL3 1 0.03 0.45 0.04 5.00
136 INT210071 Positive_regulation of Transcription of GLA 2 0.54 0.67 0.03 5.00
137 INT210062 Transcription of GLA 2 0.56 0.67 0.03 5.00
138 INT214882 Gene_expression of Atcay 2 0.17 0.67 0 5.00
139 INT296884 Negative_regulation of Negative_regulation of NPPB 1 0.01 1.37 0 5.00
140 INT210067 Protein_catabolism of RAPGEF5 1 0.05 0.24 0 5.00
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