D:Retina Disease

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Disease Term
Synonyms CENTRAL RETINAL ARTERY OCCLUSION, Central Retinal Vein Occlusion, Hypertensive Retinopathy, Nonrhegmatogenous Detachment, RETINAL DEGENERATION, RETINAL DETACHMENT, Retinal Edema, Retinal Edemas, Retinal Exudate, Retinal Haemorrhage, Retinal Haemorrhages
Documents 775
Hot Single Events 200
Hot Interactions 31

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Retina Disease. They are ordered first by their relevance to Retina Disease and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT339585 Binding of AMD1 and MDM1 1 0.06 2.02 0 99.70
2 INT285022 Regulation of Bak1 Regulation of Bcl2 1 0.09 0.71 0.17 98.96
3 INT285026 Bak1 Regulation of Bcl2 1 0.09 0.71 0.17 98.96
4 INT285024 Bcl2 Regulation of Bak1 1 0.09 0.71 0.17 98.96
5 INT262820 Binding of Aif1 and Serpinf1 1 0.01 1.3 0.27 98.48
6 INT339582 AMD1 Regulation of C1QTNF5 1 0.07 2 0 97.76
7 INT167565 Binding of ERG and LRP5 1 0.02 0.94 0.03 97.28
8 INT237745 Binding of Lgals3 and Lgals3bp 1 0.24 1.36 0.28 96.80
9 INT237750 Lgals3bp Positive_regulation of Binding of Lgals3 and Lgals3 1 0.30 1.36 0.28 96.80
10 INT237752 Lgals3bp Positive_regulation of Binding of Lgals3 and Lgals3bp 1 0.26 1.36 0.28 96.80
11 INT237753 Lgals3 Positive_regulation of Binding of Lgals3 and Lgals3bp 1 0.30 1.36 0.28 96.80
12 INT285023 Casp3 Negative_regulation of Casp7 1 0.07 0.44 0.1 94.40
13 INT254433 Binding of Lrp5 and Sost 2 0.39 1.51 0.03 91.24
14 INT335891 Binding of Dkk1 and Lrp5 1 0.39 0.57 0 91.24
15 INT277555 Clrn1 Regulation of Localization of Pdc 1 0.05 0.7 0 90.80
16 INT245722 Binding of Vsx2 and Mfrp 1 0.24 1.2 0 90.56
17 INT285077 CCL16 Positive_regulation of ITK 1 0.05 1.95 0.31 89.80
18 INT285076 CCL16 Positive_regulation of Gene_expression of ITK 1 0.05 1.8 0.14 89.80
19 INT252145 Binding of Napb and Snap25 9 0.19 0.85 0.75 89.64
20 INT300986 Negative_regulation of MAPK8 Negative_regulation of Localization of TNF 1 0.01 1.25 0.03 89.16
21 INT235168 Binding of Crx and Atxn7 1 0.11 0.81 0.03 87.88
22 INT283126 Dag1 Positive_regulation of Localization of Aqp4 1 0.47 0.2 0.07 87.56
23 INT266225 Bhlhe23 Regulation of Gene_expression of Gtf3a 1 0.01 0.33 0 86.84
24 INT19922 Binding of F13A1 and Plat 1 0.01 0.46 0.1 86.76
25 INT273466 Binding of ELOVL4 and Elovl4 1 0.14 0.3 0 86.32
26 INT288026 PROC Positive_regulation of Gene_expression of VEGFA 1 0.01 0.5 0.15 86.08
27 INT283125 Gtf3a Positive_regulation of Gfap 1 0.02 0.43 0 85.24
28 INT338162 Positive_regulation of Binding of YWHAQ and Nxnl1 1 0.49 0.26 0 83.08
29 INT301054 Tfap2a Regulation of Gene_expression of Faslg 1 0.00 1.23 0.34 82.88
30 INT173059 Binding of KDR and VEGFA 43 0.43 29.63 1.1 82.64
31 INT338161 Binding of YWHAQ and Nxnl1 1 0.37 0.26 0 82.52
32 INT342355 Arrd1 Positive_regulation of Osbpl1a 1 0.01 0.8 0.04 72.48
33 INT342359 Arrd1 Positive_regulation of Scd1 1 0.01 0.8 0.04 72.48
34 INT342356 Arrd1 Positive_regulation of Negative_regulation of Ppara 1 0.01 0.81 0.04 72.48
35 INT260495 VEGFA Positive_regulation of Grin1 1 0.08 1.08 0.12 69.20
36 INT260497 VEGFA Positive_regulation of Gria2 1 0.03 1.08 0.12 69.20
37 INT285030 Binding of Bax and Slc25a4 1 0.03 0.84 0.11 65.72
38 INT335890 Binding of Dkk1 and Lrp4 1 0.37 0.64 0.07 65.44
39 INT335886 Binding of Sost and Lrp4 1 0.28 0.65 0.07 65.44
40 INT273770 VEGFA Negative_regulation of Localization of Twist1 1 0.07 0.58 0 64.92
41 INT227398 Binding of H2afy and Alms1 1 0.01 1.42 0 63.64
42 INT227399 Binding of D5Mit424 and Alms1 1 0.01 0.71 0 63.64
43 INT266098 Bdnf Negative_regulation of Negative_regulation of 1190002H23Rik 1 0.05 0.41 0 62.24
44 INT211492 Positive_regulation of GRIN1 Positive_regulation of Prkca 1 0.01 0.87 0.36 60.88
45 INT272301 Negative_regulation of Binding of LPA and PLG 1 0.08 0.68 0 60.56
46 INT272300 Binding of LPA and PLG 1 0.09 0.66 0 60.56
47 INT259716 Loxl1 Regulation of Loxl1 1 0.00 1.84 0.08 59.92
48 INT321968 Rock1 Positive_regulation of EZR 1 0.42 1.02 0 58.72
49 INT239406 Binding of MTTP and TAOK1 1 0.02 0.51 0 56.88
50 INT239408 Binding of PADI1 and TAOK1 1 0.01 0.51 0 56.88
51 INT239407 Binding of MTTP and PADI1 1 0.23 0.5 0 55.68
52 INT295262 Tlr4 Positive_regulation of Positive_regulation of Nos2 1 0.07 0.19 0 54.96
53 INT285025 Bnip3 Positive_regulation of Bak1 1 0.11 0.78 0.07 53.12
54 INT285032 Bnip3 Positive_regulation of Bax 1 0.28 0.77 0.07 53.12
55 INT279620 Negative_regulation of Binding of Grin2a and Grin2b 1 0.18 0.99 0.4 52.96
56 INT212290 Binding of Grin2a and Grin2b 2 0.20 1.36 0.82 51.28
57 INT285031 Binding of Bcl2 and Bcl2l1 1 0.27 0.1 0 50.00
58 INT285029 Binding of Bax and Bcl2l1 1 0.25 0.1 0 50.00
59 INT285028 Binding of Bcl2 and Bax 1 0.32 0.1 0 50.00
60 INT285068 ITK Regulation of CCL16 1 0.02 1.86 0.03 48.44
61 INT285067 Negative_regulation of ITK Regulation of CCL16 1 0.04 1.1 0.03 48.44
62 INT321967 Binding of PDR and PVR 1 0.01 2.32 0 47.76
63 INT233397 Binding of ABCA4 and COL2A1 1 0.38 3.59 0.03 47.12
64 INT285047 WTS Regulation of Gene_expression of Rho 1 0.02 0 0 39.04
65 INT285042 Dbi Regulation of Gene_expression of Rho 1 0.01 0 0 38.88
66 INT212139 Slc4a3 Positive_regulation of Cl 1 0.07 0 0.12 37.84
67 INT212138 Slc4a3 Positive_regulation of Gene_expression of Cl 1 0.07 0 0.12 37.84
68 INT237748 Negative_regulation of Jak3 Negative_regulation of Positive_regulation of Stat3 1 0.25 1.01 0.22 30.64
69 INT256072 Serpina3k Negative_regulation of Positive_regulation of Ros1 1 0.04 0.49 0 29.04
70 INT259556 PLEK Negative_regulation of Gene_expression of VEGFA 1 0.46 2.15 0.73 26.64
71 INT259557 PLEK Negative_regulation of Positive_regulation of VEGFA 1 0.46 2.15 0.73 26.64
72 INT241019 Positive_regulation of Mapk1 Positive_regulation of Protein_catabolism of Hmbs 1 0.07 0.05 0 26.00
73 INT286568 Car2 Positive_regulation of Positive_regulation of Pkd1 1 0.03 0.16 0.09 20.92
74 INT286565 Pkd2 Positive_regulation of Positive_regulation of Pkd1 1 0.21 0.11 0.09 20.92
75 INT288025 VEGFA Regulation of IL6 1 0.36 0.26 0.03 19.32
76 INT288028 VEGFA Regulation of IL8 1 0.36 0.26 0.03 19.08
77 INT288027 VEGFA Regulation of CCL2 1 0.44 0.26 0.03 18.72
78 INT346746 Binding of Cacng2 and Gria2 1 0.21 0.18 0 17.80
79 INT346764 Binding of RBM10 and Gria2 1 0.01 0.18 0 17.40
80 INT175911 Binding of SERPINE1 and CNBP 1 0.01 1.02 0.22 15.48
81 INT175910 SERPINE1 Negative_regulation of PLAU 1 0.06 1.01 0.22 13.52
82 INT260496 Hif1a Regulation of Gene_expression of VEGFA 1 0.12 0.93 0 10.84
83 INT24388 CRH Positive_regulation of Localization of POMC 8 0.51 5.67 3.35 5.00
84 INT134212 CRH Regulation of Localization of POMC 1 0.47 2.89 2.9 5.00
85 INT249013 Gabrg1 Negative_regulation of Per2 1 0.34 0.07 2.31 5.00
86 INT249005 Gabrg1 Positive_regulation of Per2 1 0.39 0 1.7 5.00
87 INT101926 Binding of Dio1 and Drd2 4 0.28 0.39 1.66 5.00
88 INT249014 Gabrg1 Regulation of Per2 1 0.31 0 1.24 5.00
89 INT185321 Tlr4 Positive_regulation of Gene_expression of Il6 5 0.14 1.97 1.15 5.00
90 INT249002 Gabrg1 Positive_regulation of Protein_catabolism of Per1 1 0.35 0.09 1.15 5.00
91 INT269191 Binding of Grin1 and Grin3a 2 0.32 1.05 1.09 5.00
92 INT269189 Binding of Grin2a and Grin3a 2 0.25 1.05 1.09 5.00
93 INT249012 Binding of Akt1 and Gabrg1 1 0.01 0 0.9 5.00
94 INT249023 Gabrg1 Positive_regulation of Csn2 1 0.02 0 0.74 5.00
95 INT222811 Binding of Hand2 and TH1L 4 0.03 8.26 0.69 5.00
96 INT248998 Gabrg1 Regulation of Luc7l3 1 0.05 0 0.69 5.00
97 INT249018 Gabrg1 Regulation of Localization of Per2 1 0.35 0 0.69 5.00
98 INT249010 Gabrg1 Regulation of Positive_regulation of Per1 1 0.33 0 0.67 5.00
99 INT249008 Gabrg1 Regulation of Per1 1 0.33 0 0.67 5.00
100 INT170832 Cftr Regulation of Scnn1a 2 0.16 1.2 0.67 5.00
101 INT254199 Il10 Positive_regulation of Gene_expression of Socs3 2 0.06 0.75 0.63 5.00
102 INT255690 Binding of VEGFA and Flt1 8 0.34 3.44 0.61 5.00
103 INT200808 Binding of Akt1 and Insrr 2 0.00 0.98 0.61 5.00
104 INT249027 Gabrg1 Negative_regulation of Luc7l3 1 0.05 0.07 0.59 5.00
105 INT249029 Binding of Csn2 and Insrr 1 0.00 0 0.59 5.00
106 INT248993 Binding of Csn2 and Ptar1 1 0.00 0 0.59 5.00
107 INT248994 Binding of Akt1 and Ptar1 1 0.00 0 0.58 5.00
108 INT249009 Gabrg1 Regulation of Gene_expression of Per2 1 0.40 0 0.56 5.00
109 INT249022 Gabrg1 Regulation of Gene_expression of Luc7l3 1 0.07 0 0.56 5.00
110 INT249001 Gabrg1 Positive_regulation of Arntl 1 0.29 0 0.55 5.00
111 INT249006 Gabrg1 Positive_regulation of Transcription of Arntl 1 0.31 0 0.55 5.00
112 INT249024 Gabrg1 Positive_regulation of Transcription of Per1 1 0.59 0 0.55 5.00
113 INT249020 Gabrg1 Positive_regulation of Per1 1 0.40 0 0.55 5.00
114 INT248997 Gabrg1 Positive_regulation of Clock 1 0.37 0 0.54 5.00
115 INT259184 Binding of Gria2 and Gria1 2 0.26 0.28 0.54 5.00
116 INT248995 Gabrg1 Regulation of Transcription of Clock 1 0.36 0 0.54 5.00
117 INT249007 Gabrg1 Regulation of Transcription of Per2 1 0.35 0 0.54 5.00
118 INT249016 Gabrg1 Positive_regulation of Transcription of Clock 1 0.37 0 0.54 5.00
119 INT248996 Gabrg1 Negative_regulation of Gene_expression of Per2 1 0.33 0 0.51 5.00
120 INT249025 Gabrg1 Negative_regulation of Gene_expression of Luc7l3 1 0.07 0 0.51 5.00
121 INT249026 Gabrg1 Positive_regulation of Luc7l3 1 0.06 0 0.51 5.00
122 INT215543 Negative_regulation of Trim33 Negative_regulation of Gopc 1 0.15 0.35 0.48 5.00
123 INT295270 S100a8 Regulation of Il6 1 0.01 0.56 0.48 5.00
124 INT249000 Helt Negative_regulation of Per2 1 0.01 0 0.48 5.00
125 INT264136 IFNA1 Positive_regulation of Socs3 1 0.01 0.38 0.46 5.00
126 INT264137 IFNA1 Positive_regulation of Socs1 1 0.01 0.38 0.46 5.00
127 INT262815 Gene_expression of Serpinf1 Negative_regulation of Gene_expression of Gfap 1 0.39 2.73 0.44 5.00
128 INT249021 Gabrg1 Negative_regulation of Th 1 0.08 0.06 0.44 5.00
129 INT353109 Binding of VEGFA and Aes 1 0.02 3.93 0.43 5.00
130 INT262819 Gene_expression of Serpinf1 Negative_regulation of Binding of 1190002H23Rik 1 0.05 2.66 0.43 5.00
131 INT249011 Gabrg1 Regulation of Clock 1 0.19 0 0.43 5.00
132 INT264135 Socs1 Positive_regulation of Protein_catabolism of TOLLIP 1 0.00 0.33 0.41 5.00
133 INT191493 Binding of AGTR1 and NLRP3 2 0.03 2.35 0.39 5.00
134 INT262824 Gene_expression of Serpinf1 Negative_regulation of Gene_expression of Il18 1 0.39 1.56 0.37 5.00
135 INT249004 Helt Regulation of Clock 1 0.01 0.09 0.37 5.00
136 INT249015 Regulation of Helt Regulation of Clock 1 0.01 0.09 0.37 5.00
137 INT249019 Gabrg1 Positive_regulation of Akt1 1 0.02 0 0.34 5.00
138 INT242162 Binding of Ccnd1 and Wnt2 1 0.10 0.23 0.34 5.00
139 INT287380 Binding of VEGFA and Kdr 12 0.18 11.97 0.34 5.00
140 INT242164 Wnt2 Positive_regulation of Localization of Apc 1 0.13 1.53 0.32 5.00
141 INT252140 Binding of Cck and Snap25 1 0.30 0.39 0.3 5.00
142 INT215789 Fig4 Positive_regulation of Localization of P2rx7 1 0.03 0.53 0.29 5.00
143 INT182499 Binding of AGTR1 and AGTR2 3 0.20 2.79 0.28 5.00
144 INT262826 Serpinf1 Negative_regulation of Gene_expression of TNF 1 0.29 1.83 0.28 5.00
145 INT172465 Binding of Rab27a and Rab27b 2 0.41 1.71 0.27 5.00
146 INT263587 Pdia3 Negative_regulation of Binding of Esr1 1 0.07 1.86 0.26 5.00
147 INT346745 Binding of Cacng2 and Grip2 1 0.01 0 0.25 5.00
148 INT237749 Prkcg Regulation of Transcription of Pcgf1 1 0.14 0.68 0.25 5.00
149 INT346765 Binding of RBM10 and Grip2 1 0.00 0 0.25 5.00
150 INT295266 S100a8 Regulation of Cxcl10 1 0.01 0.28 0.24 5.00
151 INT295269 S100a8 Regulation of Irf7 1 0.01 0.28 0.24 5.00
152 INT230748 Agtr2 Positive_regulation of Gene_expression of Ros1 2 0.05 1.04 0.23 5.00
153 INT289998 CNTF Negative_regulation of Casp3 1 0.04 0.99 0.22 5.00
154 INT289981 Cntf Negative_regulation of Casp3 1 0.02 1.01 0.22 5.00
155 INT262817 Serpinf1 Regulation of Positive_regulation of 1190002H23Rik 1 0.06 1.3 0.22 5.00
156 INT289997 CNTF Negative_regulation of Binding of CNTF and Casp3 1 0.05 0.99 0.22 5.00
157 INT289999 Binding of CNTF and Casp3 1 0.04 0.99 0.22 5.00
158 INT233929 PPARA Negative_regulation of ras 1 0.02 2.39 0.22 5.00
159 INT264134 Binding of IFNA1 and Tlr4 1 0.01 1.5 0.22 5.00
160 INT335888 Lrp5 Negative_regulation of Gene_expression of Tph1 1 0.22 0.15 0.21 5.00
161 INT274080 Binding of ARHGAP4 and Map3k5 1 0.41 1.92 0.2 5.00
162 INT304882 Agtr2 Positive_regulation of Mapk1 1 0.07 0.95 0.2 5.00
163 INT175909 Binding of ROS1 and CNBP 1 0.01 1.78 0.19 5.00
164 INT175908 Binding of NOS3 and ROS1 1 0.10 1.84 0.19 5.00
165 INT262818 Serpinf1 Negative_regulation of Gene_expression of Gfap 1 0.45 0.71 0.18 5.00
166 INT262822 Serpinf1 Negative_regulation of Negative_regulation of 1190002H23Rik 1 0.07 1.27 0.18 5.00
167 INT295268 S100a8 Positive_regulation of Stat3 1 0.00 0.5 0.18 5.00
168 INT346748 Binding of Shisa9 and Grip2 1 0.00 0 0.17 5.00
169 INT233904 NLRP3 Positive_regulation of AGT 1 0.06 0.81 0.17 5.00
170 INT346766 Negative_regulation of Binding of RBM10 and Grip2 1 0.00 0 0.17 5.00
171 INT234303 Gria3 Negative_regulation of Gria4 1 0.36 0 0.16 5.00
172 INT295273 STAT1 Regulation of Transcription of Hp 1 0.00 0.63 0.15 5.00
173 INT295265 Jun Regulation of Gtf3a 1 0.00 0.34 0.15 5.00
174 INT295272 STAT1 Regulation of Hp 1 0.00 0.63 0.14 5.00
175 INT295271 STAT1 Regulation of Gbp2 1 0.00 0.63 0.14 5.00
176 INT184704 Binding of Prrx2 and Sr1 1 0.21 1.65 0.13 5.00
177 INT295267 Binding of Hmox1 and Gtf3a 1 0.01 0.49 0.13 5.00
178 INT295261 Binding of Hmox1 and Nfe2l2 1 0.17 0.49 0.13 5.00
179 INT242163 Wnt2 Positive_regulation of Regulation of Apc 1 0.13 0.71 0.13 5.00
180 INT295264 Positive_regulation of Binding of Hmox1 and Nfe2l2 1 0.25 0.5 0.13 5.00
181 INT347065 Binding of Gnat2 and Rho 1 0.14 0 0.12 5.00
182 INT262618 Binding of SOAT1 and Kras 1 0.00 0.81 0.12 5.00
183 INT261690 Binding of GSC and TCF23 1 0.10 0 0.12 5.00
184 INT237746 Prkcg Regulation of Pcgf1 1 0.14 0.34 0.12 5.00
185 INT311399 Binding of Celf1 and Uts2r 1 0.08 0.26 0.12 5.00
186 INT228453 Igf1 Positive_regulation of Prkca 2 0.12 1.17 0.12 5.00
187 INT235775 Binding of Tnfrsf1a and Tradd 3 0.31 3 0.12 5.00
188 INT321965 Rock1 Positive_regulation of Nos3 1 0.28 1.99 0.12 5.00
189 INT278423 Binding of Emp1 and Map2 1 0.06 0.46 0.12 5.00
190 INT287381 Cxcl2 Regulation of Gene_expression of VEGFA 1 0.42 1.1 0.1 5.00
191 INT286418 Gtf3a Positive_regulation of Akt1 1 0.01 0.45 0.1 5.00
192 INT234302 Negative_regulation of Gria3 Positive_regulation of Swd1 1 0.01 0.47 0.1 5.00
193 INT241248 Binding of Pkd1 and Pkd2 3 0.22 1.52 0.1 5.00
194 INT286432 Binding of ANTXR2 and Gtf3a 1 0.00 3.56 0.1 5.00
195 INT304881 Ros1 Positive_regulation of Mapk1 1 0.25 0.36 0.1 5.00
196 INT277089 VEGFA Positive_regulation of Icam1 1 0.02 1.74 0.09 5.00
197 INT304887 Agtr2 Positive_regulation of Positive_regulation of Mapk1 1 0.10 0.45 0.09 5.00
198 INT304886 Agtr2 Positive_regulation of Ros1 1 0.03 0.45 0.09 5.00
199 INT199667 Cep290 Regulation of Atf4 1 0.04 1.96 0.09 5.00
200 INT277091 VEGFA Positive_regulation of Fas 1 0.03 1.72 0.09 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Retina Disease. They are ordered first by their pain relevance and then by number of times they were reported in Retina Disease. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT277526 Gene_expression of Clrn1 1 0.78 29.02 0.17 100.00
2 INT5379 Gene_expression of Fos 656 0.78 255.5 292.54 100.00
3 INT80939 Positive_regulation of PDR 8 0.55 5.43 0.67 100.00
4 INT155680 Gene_expression of Slc1a3 22 0.66 6.76 7.23 100.00
5 INT94649 Gene_expression of Grm1 19 0.77 5.11 6.58 100.00
6 INT18681 Gene_expression of Thy1 80 0.71 38.8 5.23 100.00
7 INT26585 Gene_expression of Vim 117 0.77 39.97 6 100.00
8 INT226933 Gene_expression of Rhod 2 0.46 0.2 0.35 100.00
9 INT242144 Regulation of Rp1 2 0.22 1.13 0.05 100.00
10 INT277549 Gene_expression of Leprel2 1 0.01 0.19 0.04 100.00
11 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73 99.98
12 INT283120 Regulation of Gene_expression of Dag1 4 0.52 1.32 0.38 99.98
13 INT283113 Regulation of Transcription of Dag1 1 0.52 0.44 0 99.98
14 INT164117 Positive_regulation of Negative_regulation of 1190002H23Rik 3 0.40 2.16 0.27 99.98
15 INT190479 Positive_regulation of 1190002H23Rik 6 0.07 5.64 0.53 99.98
16 INT105393 Positive_regulation of Localization of VEGFA 66 0.70 45.45 4.9 99.98
17 INT174277 Positive_regulation of Positive_regulation of Gopc 23 0.33 8.08 3.73 99.98
18 INT277537 Transcription of Clrn1 1 0.72 5.06 0 99.94
19 INT277531 Regulation of Transcription of Clrn1 1 0.45 1.48 0 99.94
20 INT1982 Regulation of NARFL 119 0.49 116.2 14.35 99.92
21 INT209418 Negative_regulation of CLTA 2 0.06 1.62 0.03 99.90
22 INT1767 Positive_regulation of PROC 83 0.67 54.14 17 99.84
23 INT3777 Positive_regulation of NARFL 256 0.56 302.43 25.74 99.84
24 INT277529 Positive_regulation of Gmcl1 5 0.19 3.67 0.42 99.84
25 INT277541 Gene_expression of Rp1 1 0.62 0.61 0.12 99.84
26 INT277548 Negative_regulation of Gene_expression of Rp1 1 0.34 0.2 0.04 99.84
27 INT164116 Negative_regulation of 1190002H23Rik 33 0.51 18.73 2.71 99.82
28 INT101992 Localization of VEGFA 413 0.81 258.23 36.15 99.80
29 INT9886 Gene_expression of Ptgs1 92 0.77 40.66 25.31 99.80
30 INT283100 Negative_regulation of Gene_expression of Kcnj14 1 0.02 0.38 0 99.78
31 INT273461 Gene_expression of Elovl4 15 0.75 4.21 0.08 99.76
32 INT169926 Positive_regulation of Gopc 416 0.46 157.8 58.67 99.76
33 INT264114 Binding of Mertk 1 0.07 0.44 0.26 99.76
34 INT260465 Positive_regulation of Hk2 2 0.44 2.95 0.04 99.72
35 INT104912 Gene_expression of Acvr2a 8 0.63 4.48 1.81 99.64
36 INT286082 Positive_regulation of Gene_expression of Acvr2a 1 0.06 1.25 0 99.64
37 INT26295 Positive_regulation of mea 4 0.49 1.08 0.91 99.62
38 INT263573 Negative_regulation of Gmcl1 3 0.20 1.7 0.23 99.56
39 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 99.54
40 INT101474 Positive_regulation of Gene_expression of Gfap 61 0.70 38.3 10.35 99.54
41 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65 99.46
42 INT174986 Gene_expression of AIRN 20 0.57 6.13 0.64 99.46
43 INT86111 Positive_regulation of Positive_regulation of VEGFA 38 0.69 33.81 5.78 99.46
44 INT173693 Localization of Gopc 249 0.65 70.49 38.81 99.44
45 INT202817 Gene_expression of Dag1 16 0.75 7.82 1.3 99.40
46 INT283107 Transcription of Dag1 1 0.61 0.44 0 99.40
47 INT273454 Gene_expression of Fat1 21 0.76 6.6 0.18 99.38
48 INT213722 Positive_regulation of PVR 3 0.25 2.4 0.94 99.36
49 INT321960 Regulation of Negative_regulation of PVR 1 0.12 0.93 0.05 99.36
50 INT321963 Positive_regulation of Negative_regulation of PVR 1 0.12 0.93 0.05 99.36
51 INT273613 Negative_regulation of PVR 7 0.17 5.06 1.26 99.36
52 INT155724 Negative_regulation of Transcription of Bcl2 6 0.53 2.35 0.37 99.36
53 INT283112 Gene_expression of Kcnj14 1 0.03 2.48 0.53 99.34
54 INT3361 Positive_regulation of Esr1 273 0.69 208.53 44.81 99.32
55 INT138201 Transcription of PAEP 4 0.67 1.8 1.02 99.28
56 INT91445 Regulation of Bcl2 50 0.56 38.8 7.41 99.26
57 INT101645 Regulation of Gene_expression of Bcl2l1 8 0.36 5.27 2.05 99.24
58 INT66200 Gene_expression of Gfap 215 0.78 88.04 28.25 99.22
59 INT211095 Negative_regulation of Dag1 14 0.57 7.18 1.07 99.20
60 INT283101 Negative_regulation of Gene_expression of Dag1 1 0.57 0.96 0 99.20
61 INT99068 Gene_expression of Mapk8 62 0.78 33.57 21.25 99.20
62 INT328648 Negative_regulation of Gene_expression of Rho 1 0.19 0.54 0 99.16
63 INT101957 Transcription of Bcl2 30 0.69 16.57 4.3 99.12
64 INT237735 Negative_regulation of Lgals3 2 0.30 1.39 0.27 99.08
65 INT235160 Gene_expression of Atxn7 1 0.56 2 0.04 99.00
66 INT254429 Negative_regulation of Lrp5 4 0.57 1.95 0.18 99.00
67 INT100423 Gene_expression of Bax 141 0.75 98.43 24.48 98.96
68 INT285007 Regulation of Bak1 1 0.20 3.46 0.56 98.96
69 INT48692 Binding of VEGFA 345 0.48 210.3 21.31 98.96
70 INT172458 Regulation of Gopc 155 0.53 62.57 24.86 98.96
71 INT1049 Positive_regulation of hpc 18 0.40 3.16 8.45 98.96
72 INT10147 Gene_expression of Serpinc1 28 0.76 17.73 5.77 98.92
73 INT9408 Positive_regulation of Crp 296 0.69 242.27 57.35 98.88
74 INT200750 Gene_expression of Rho 19 0.65 6.52 0.69 98.84
75 INT204805 Regulation of Xiap 3 0.40 3.98 0.17 98.84
76 INT76336 Negative_regulation of PDE5A 192 0.59 112.02 20.09 98.84
77 INT99505 Gene_expression of Bcl2l1 42 0.77 33.12 10.15 98.80
78 INT283116 Regulation of Negative_regulation of Aqp4 1 0.41 0.32 0 98.80
79 INT328647 Negative_regulation of Pkn3 1 0.03 0.64 0 98.76
80 INT328642 Negative_regulation of Trav6n-6 1 0.00 0.57 0 98.76
81 INT287345 Positive_regulation of CORD1 1 0.26 0.71 0 98.76
82 INT283115 Localization of Kcnj14 5 0.04 1.47 0.31 98.74
83 INT57232 Binding of Casp3 22 0.36 9.42 6.2 98.68
84 INT62301 Regulation of EIF4E2 2 0.19 3.2 0.71 98.64
85 INT145929 Regulation of Bax 20 0.60 18.12 5.35 98.52
86 INT277542 Negative_regulation of Pdc 1 0.03 1.61 0 98.50
87 INT283102 Positive_regulation of Dag1 1 0.49 1.31 0.21 98.50
88 INT196319 Binding of Serpinf1 4 0.41 2.46 0.27 98.48
89 INT273455 Positive_regulation of Gene_expression of Elovl4 1 0.67 0.52 0 98.48
90 INT157378 Gene_expression of PDR 14 0.53 11.46 0.64 98.44
91 INT109925 Gene_expression of RPE 11 0.65 12.46 0.68 98.44
92 INT144617 Gene_expression of RHO 13 0.75 1.74 0.38 98.44
93 INT169776 Gene_expression of Opn4 52 0.77 8.75 1.38 98.40
94 INT82448 Gene_expression of S100a8 246 0.77 236.72 84.02 98.36
95 INT266875 Positive_regulation of Narfl 37 0.05 38.43 3.73 98.32
96 INT102106 Positive_regulation of Bax 48 0.67 30.62 9.28 98.32
97 INT116614 Positive_regulation of Gene_expression of Bcl2l1 12 0.67 11.39 4.68 98.32
98 INT69768 Negative_regulation of Pscs 7 0.51 4.76 2.82 98.28
99 INT7533 Gene_expression of Tlr4 720 0.78 343.22 121.57 98.24
100 INT81289 Positive_regulation of Gene_expression of Tlr4 192 0.69 104.5 33.89 98.24
101 INT242145 Regulation of Gene_expression of Sfrp1 1 0.17 0.99 0 98.24
102 INT233399 Binding of ABCA4 9 0.46 9.49 0.07 98.12
103 INT328644 Gene_expression of Trav6n-6 1 0.01 1.68 0 98.08
104 INT14151 Gene_expression of Casp3 311 0.78 140.26 120.68 98.06
105 INT229855 Gene_expression of Casp7 3 0.28 2.3 0.38 98.06
106 INT99070 Gene_expression of Mapk14 147 0.78 103.99 79.59 98.04
107 INT137271 Positive_regulation of PDE6B 4 0.29 1.95 1.53 97.96
108 INT218919 Negative_regulation of Xiap 4 0.32 4.61 0.46 97.96
109 INT192536 Gene_expression of PDE6B 2 0.65 1.18 0 97.96
110 INT174541 Positive_regulation of Gene_expression of COL5A2 18 0.36 14.17 2.12 97.92
111 INT1951 Positive_regulation of Tlr4 345 0.70 176.99 62.42 97.84
112 INT178306 Negative_regulation of Gene_expression of Gopc 71 0.37 26.43 9.74 97.84
113 INT273456 Gene_expression of Pkn3 8 0.06 3.32 0 97.80
114 INT170054 Negative_regulation of Gopc 280 0.38 117.89 42.4 97.76
115 INT84260 Positive_regulation of Mapk8 124 0.69 72.84 35.98 97.72
116 INT152927 Negative_regulation of Mapk1 16 0.41 5.85 2.73 97.72
117 INT10889 Gene_expression of F8 60 0.78 41.36 5.06 97.68
118 INT192537 Gene_expression of AIPL1 2 0.42 1.36 0 97.60
119 INT282798 Binding of Prkd1 2 0.18 2.11 0.19 97.56
120 INT72182 Gene_expression of Mcpt1 167 0.75 123.7 52.15 97.56
121 INT80124 Negative_regulation of VEGFA 450 0.58 311.19 44.53 97.52
122 INT139862 Negative_regulation of amd 8 0.35 10.15 0.6 97.52
123 INT233923 Regulation of Localization of PDR 1 0.08 2.04 0.18 97.52
124 INT342321 Gene_expression of Rdh9 1 0.75 1.1 0.07 97.52
125 INT342337 Positive_regulation of Gene_expression of Rdh18-ps 1 0.44 0.9 0.07 97.52
126 INT342323 Gene_expression of Rdh18-ps 1 0.68 0.9 0.07 97.52
127 INT342334 Positive_regulation of Gene_expression of Rdh9 1 0.48 1.1 0.07 97.52
128 INT158124 Gene_expression of COL5A2 136 0.69 72.3 12.44 97.48
129 INT204795 Gene_expression of Xiap 9 0.60 15.32 0.7 97.44
130 INT165799 Negative_regulation of Gene_expression of Bcl2l1 6 0.41 5.12 0.47 97.40
131 INT30870 Negative_regulation of Adra2b 8 0.44 4.5 2.8 97.40
132 INT283105 Positive_regulation of Gene_expression of Dag1 1 0.67 1.19 0.17 97.36
133 INT102839 Gene_expression of Pdc 15 0.52 6.3 1.87 97.36
134 INT82140 Negative_regulation of Raf1 3 0.14 1.7 1.38 97.28
135 INT109651 Negative_regulation of Aqp4 23 0.53 8.5 10.7 97.26
136 INT289494 Regulation of 1190002H23Rik 1 0.04 1.64 0 97.20
137 INT90897 Regulation of Rab27a 6 0.45 3.28 0.5 97.16
138 INT86673 Positive_regulation of Bcl2 77 0.70 57.74 17.37 97.04
139 INT242136 Gene_expression of Sfrp1 3 0.46 2.75 0.05 97.04
140 INT242146 Positive_regulation of Gene_expression of Sfrp1 2 0.30 1.68 0.05 97.04
141 INT243222 Gene_expression of Rs1 6 0.78 8.49 0.17 97.00
142 INT243226 Positive_regulation of Rs1 3 0.70 5.6 0.31 97.00
143 INT283111 Regulation of Kcnj14 1 0.01 0.38 0 96.96
144 INT102110 Positive_regulation of Gene_expression of Bax 42 0.67 35.77 9.51 96.92
145 INT4991 Positive_regulation of Vim 74 0.69 69.84 8.33 96.88
146 INT83295 Positive_regulation of Cd68 21 0.39 14.55 2.46 96.88
147 INT237733 Binding of Lgals3bp 1 0.26 1.33 0.27 96.80
148 INT213648 Phosphorylation of S100A6 2 0.30 1.43 0.36 96.76
149 INT324655 Gene_expression of Vash1 1 0.78 10.63 0.38 96.76
150 INT235748 Negative_regulation of Yy1 1 0.27 1.34 0.1 96.76
151 INT324647 Positive_regulation of Gene_expression of Vash1 1 0.70 1.04 0.05 96.76
152 INT120811 Gene_expression of Gopc 1174 0.59 428.49 150.55 96.68
153 INT104493 Negative_regulation of Mapk8 56 0.53 27.76 16.86 96.68
154 INT99507 Positive_regulation of Bcl2l1 17 0.69 9.23 4.97 96.64
155 INT164465 Negative_regulation of Sbp 12 0.33 10.31 0.56 96.64
156 INT169670 Gene_expression of PHARC 1 0.14 1.41 0.35 96.52
157 INT123563 Negative_regulation of Rock1 7 0.55 16.56 5.78 96.48
158 INT10448 Positive_regulation of Srf 3 0.47 0.89 1.03 96.48
159 INT8694 Binding of Lgals3 38 0.48 14.82 8.05 96.40
160 INT196967 Gene_expression of mea 9 0.27 1.47 1.55 96.32
161 INT291897 Positive_regulation of Gene_expression of mea 2 0.20 0.61 0.11 96.32
162 INT273464 Gene_expression of ELOVL4 1 0.20 0.37 0 96.32
163 INT158863 Negative_regulation of Ros1 84 0.35 40.3 10.14 96.28
164 INT269748 Positive_regulation of AMD1 4 0.43 3.56 0.28 96.28
165 INT5840 Transcription of Gfap 26 0.71 18.18 10.41 96.24
166 INT5839 Positive_regulation of Transcription of Gfap 10 0.49 11.61 6.74 96.24
167 INT940 Negative_regulation of Ptgs1 219 0.59 104.34 95.97 96.16
168 INT1060 Negative_regulation of Pla2g1b 50 0.57 22.91 18.12 96.16
169 INT235141 Binding of Atxn7 1 0.40 0.81 0 96.08
170 INT33008 Gene_expression of Dync1h1 41 0.68 23.85 3.82 96.04
171 INT130149 Binding of Bre 3 0.26 0.64 0.19 96.04
172 INT159750 Negative_regulation of Gene_expression of Mapk14 15 0.40 10.88 7.81 96.00
173 INT79281 Gene_expression of Tgm2 14 0.76 7.46 2.37 96.00
174 INT6117 Gene_expression of Gmcl1 4 0.49 2.39 2.33 95.96
175 INT219218 Positive_regulation of Negative_regulation of Rgc32 3 0.06 2.96 0.03 95.96
176 INT184692 Positive_regulation of 10S 1 0.02 4.47 1.01 95.84
177 INT22546 Positive_regulation of Gene_expression of Casp3 97 0.70 47.89 51.92 95.76
178 INT285009 Negative_regulation of Gene_expression of Casp7 1 0.16 1 0.26 95.76
179 INT90313 Negative_regulation of Gene_expression of Casp3 57 0.57 22.23 26.77 95.76
180 INT285004 Positive_regulation of Gene_expression of Casp7 1 0.16 0.44 0.1 95.76
181 INT96269 Positive_regulation of Mcpt1 71 0.61 52.38 20.4 95.68
182 INT1981 Negative_regulation of NARFL 219 0.47 223.48 16.41 95.68
183 INT277547 Negative_regulation of Gene_expression of Clrn1 1 0.43 1.03 0 95.68
184 INT159060 Localization of PDR 8 0.65 10.45 0.96 95.64
185 INT233922 Positive_regulation of Localization of PDR 1 0.09 2.01 0.18 95.64
186 INT208140 Localization of PITX1 2 0.73 6.18 0.14 95.60
187 INT128695 Regulation of Gene_expression of Mapk14 14 0.44 11.49 7.14 95.56
188 INT242132 Localization of Sfrp2 3 0.70 5.01 0 95.46
189 INT57187 Positive_regulation of Gfap 49 0.69 27.59 11.46 95.44
190 INT72947 Binding of CHM 9 0.42 5.86 0.06 95.40
191 INT277551 Regulation of Gene_expression of Clrn1 1 0.45 1.18 0 95.36
192 INT288032 Negative_regulation of Localization of PDR 1 0.20 1.24 0.19 95.36
193 INT321961 Gene_expression of Rock1 1 0.51 0.79 0 95.32
194 INT5843 Positive_regulation of Gfap 184 0.70 108.2 70.21 95.28
195 INT290576 Positive_regulation of NPTX2 1 0.06 3.32 0.31 95.28
196 INT116824 Negative_regulation of Rgc32 21 0.31 21.62 2.46 95.24
197 INT338159 Gene_expression of Nxnl1 1 0.56 0.41 0 95.20
198 INT184698 Positive_regulation of Prrx2 1 0.38 3.21 1.01 95.20
199 INT89395 Negative_regulation of AKT1 127 0.58 70.27 12.54 95.12
200 INT300989 Positive_regulation of Negative_regulation of AKT1 2 0.41 1.27 0.03 95.12
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