D:Retinal Artery Occlusion

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pChart

Disease Term
Synonyms Branch Retinal Artery Occlusion, CENTRAL RETINAL ARTERY OCCLUSION, Occlusion Retinal Artery, Occlusions Retinal Artery, Retinal Artery Occlusions
Documents 52
Hot Single Events 11
Hot Interactions 2

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Retinal Artery Occlusion. They are ordered first by their relevance to Retinal Artery Occlusion and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT272301 Negative_regulation of Binding of LPA and PLG 1 0.08 0.68 0 91.40
2 INT272300 Binding of LPA and PLG 1 0.09 0.66 0 91.40
3 INT274080 Binding of ARHGAP4 and Map3k5 1 0.41 1.92 0.2 60.00
4 INT329015 Binding of APCS and SRGN 1 0.08 1.14 0.04 5.00
5 INT274078 Binding of Mapk8 and Gmcl1 1 0.05 0.68 0.04 5.00
6 INT331897 Binding of PDE5A and Pde5a 1 0.02 0.64 0.03 5.00
7 INT274076 Binding of Map3k5 and Gmcl1 1 0.06 1.23 0 5.00
8 INT274077 Binding of Tnfrsf1b and Positive_regulation of Mapk8 1 0.14 0.97 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Retinal Artery Occlusion. They are ordered first by their pain relevance and then by number of times they were reported in Retinal Artery Occlusion. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT242921 Positive_regulation of Aoc2-ps1 1 0.12 1.82 0.04 100.00
2 INT229743 Negative_regulation of AOC2 2 0.42 2.03 0.21 100.00
3 INT9649 Positive_regulation of LPA 105 0.69 74.75 13.89 99.92
4 INT11957 Negative_regulation of LPA 52 0.59 39.09 6.84 86.04
5 INT9650 Gene_expression of LPA 141 0.75 104.57 29 86.04
6 INT35144 Negative_regulation of Gene_expression of PLG 3 0.29 0.98 0.06 85.36
7 INT4561 Gene_expression of PLG 32 0.75 17.59 6.21 84.96
8 INT2921 Positive_regulation of F8 53 0.59 41.56 8.56 84.92
9 INT9900 Positive_regulation of Vwf 80 0.69 51.85 18.13 84.92
10 INT10889 Gene_expression of F8 60 0.78 41.36 5.06 83.20
11 INT44323 Positive_regulation of F8 32 0.60 24.88 3.89 80.24
12 INT107514 Positive_regulation of Akr1b1 6 0.70 7.64 3.21 77.96
13 INT103327 Gene_expression of F8 45 0.71 32.5 2.12 71.60
14 INT188724 Gene_expression of IGLV3-1 29 0.75 20.88 0.51 71.04
15 INT9951 Gene_expression of ANGPTL5 45 0.53 37.2 6.44 63.44
16 INT5913 Binding of OPA1 12 0.41 9.33 2.92 60.40
17 INT9659 Gene_expression of Il6 991 0.78 715.11 265.57 58.08
18 INT8243 Positive_regulation of Il6 451 0.70 358.24 119.28 58.08
19 INT9657 Positive_regulation of Gene_expression of Il6 237 0.70 180.45 63.6 58.08
20 INT272308 Positive_regulation of PFDN4 1 0.67 0.73 0 56.96
21 INT541 Positive_regulation of MBP 31 0.67 28.56 12.24 51.60
22 INT8683 Positive_regulation of F3 31 0.67 42.89 6.21 50.00
23 INT263932 Positive_regulation of PROCR 6 0.67 2.43 0.46 50.00
24 INT109881 Positive_regulation of Gene_expression of F8 11 0.47 12.97 1.54 42.72
25 INT24068 Localization of Hspb1 6 0.78 6.11 2.75 41.88
26 INT24069 Negative_regulation of Localization of Hspb1 3 0.14 3.93 1.3 41.88
27 INT86705 Gene_expression of BTG3 41 0.65 37.29 8.29 38.48
28 INT16996 Gene_expression of PRTN3 113 0.75 85.61 22.57 38.28
29 INT242208 Regulation of Gene_expression of SRGN 7 0.29 3.15 0.52 35.12
30 INT329016 Regulation of Gene_expression of GON4L 1 0.06 1.12 0.05 35.12
31 INT329020 Regulation of GON4L 1 0.06 1.12 0.05 35.12
32 INT105571 Gene_expression of SRGN 33 0.58 14.68 1.19 33.04
33 INT227780 Gene_expression of GON4L 2 0.13 2.72 0.05 32.72
34 INT1033 Positive_regulation of Ca2 507 0.68 131.76 147.64 24.88
35 INT23094 Positive_regulation of Positive_regulation of Ca2 29 0.49 6.8 9.35 24.88
36 INT202360 Positive_regulation of Map2k4 2 0.48 9.89 0.29 23.48
37 INT43997 Positive_regulation of Gene_expression of Esr1 57 0.51 36.66 5.51 14.88
38 INT5374 Gene_expression of Esr1 412 0.77 263.89 67.34 14.48
39 INT274069 Binding of Map3k5 1 0.29 2.68 0.49 12.64
40 INT274074 Binding of Map2k4 1 0.08 1.98 0.36 12.20
41 INT21569 Binding of Mapk8 8 0.48 5.55 3.44 11.80
42 INT1045 Localization of LH 1211 0.81 87.04 456.25 5.00
43 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 5.00
44 INT4259 Positive_regulation of Npr1 262 0.70 49.37 123.11 5.00
45 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73 5.00
46 INT117713 Phosphorylation of Akt1 275 0.82 95.82 54.34 5.00
47 INT157666 Positive_regulation of GOPC 335 0.60 120.19 42.75 5.00
48 INT84260 Positive_regulation of Mapk8 124 0.69 72.84 35.98 5.00
49 INT95734 Phosphorylation of Mapk8 108 0.82 49.92 33.52 5.00
50 INT99068 Gene_expression of Mapk8 62 0.78 33.57 21.25 5.00
51 INT18012 Gene_expression of EPO 169 0.78 108.36 13.75 5.00
52 INT21979 Negative_regulation of EDN1 52 0.58 24.65 12.55 5.00
53 INT32203 Negative_regulation of Crp 48 0.58 32.77 11.89 5.00
54 INT94859 Negative_regulation of Pde5a 67 0.43 33.66 10.28 5.00
55 INT120967 Negative_regulation of Phosphorylation of Akt1 47 0.57 23.67 8.98 5.00
56 INT99071 Positive_regulation of Gene_expression of Mapk8 16 0.55 9.87 7.58 5.00
57 INT15367 Gene_expression of OPA1 35 0.67 24.9 5.45 5.00
58 INT33854 Localization of OPA1 19 0.65 10.55 5.04 5.00
59 INT124655 Negative_regulation of PECAM1 13 0.23 10.32 3.78 5.00
60 INT24883 Regulation of OPA1 14 0.45 9.73 3.44 5.00
61 INT184255 Binding of Tnfrsf1b 4 0.43 4.45 2.78 5.00
62 INT8112 Regulation of EPO 38 0.58 22.04 2.76 5.00
63 INT168188 Gene_expression of PLXNA2 13 0.58 9 2.73 5.00
64 INT92877 Gene_expression of PDE5A 35 0.76 17.1 2.7 5.00
65 INT8111 Localization of EPO 32 0.81 19.53 2.54 5.00
66 INT257299 Binding of Pde5a 14 0.27 4.31 2.45 5.00
67 INT6117 Gene_expression of Gmcl1 4 0.49 2.39 2.33 5.00
68 INT18853 Negative_regulation of APCS 13 0.57 4.51 2.3 5.00
69 INT114746 Gene_expression of Sepp1 15 0.60 3.33 1.86 5.00
70 INT93350 Binding of Lepr 17 0.05 27.21 1.5 5.00
71 INT27762 Positive_regulation of Gene_expression of EPO 18 0.70 17.67 1.45 5.00
72 INT85378 Binding of Pdss1 6 0.28 3.81 1.35 5.00
73 INT242945 Localization of PDE5A 9 0.75 4.57 1.28 5.00
74 INT190067 Binding of Traf2 5 0.20 3.28 1.27 5.00
75 INT79598 Regulation of PDE5A 16 0.60 8.68 1.17 5.00
76 INT103043 Binding of PDE5A 16 0.37 7.79 1.12 5.00
77 INT153129 Positive_regulation of Pdss1 25 0.21 5.83 1.1 5.00
78 INT228770 Gene_expression of amd 16 0.57 21.49 1.05 5.00
79 INT318710 Positive_regulation of Gene_expression of Sept3 2 0.25 3.24 0.71 5.00
80 INT276227 Gene_expression of UBL4A 9 0.20 7.12 0.64 5.00
81 INT212562 Positive_regulation of Adrm1 16 0.10 5.08 0.62 5.00
82 INT293957 Localization of PION 1 0.55 2 0.53 5.00
83 INT274072 Gene_expression of Map3k5 1 0.60 6.69 0.5 5.00
84 INT34976 Positive_regulation of Gene_expression of OPA1 4 0.43 4.21 0.4 5.00
85 INT202347 Gene_expression of Map2k4 13 0.74 11.68 0.4 5.00
86 INT79599 Protein_catabolism of PDE5A 7 1.00 3.16 0.39 5.00
87 INT318712 Gene_expression of Sept3 2 0.34 2.2 0.35 5.00
88 INT303483 Positive_regulation of PDE5A 2 0.39 1.5 0.23 5.00
89 INT274071 Positive_regulation of Map3k5 3 0.38 2.31 0.22 5.00
90 INT261019 Positive_regulation of Gmcl1 10 0.44 5.14 0.15 5.00
91 INT274070 Positive_regulation of Gene_expression of Gmcl1 1 0.13 1.18 0.13 5.00
92 INT59286 Regulation of Gene_expression of EPO 7 0.62 6.13 0.13 5.00
93 INT242922 Positive_regulation of Gene_expression of amd 2 0.43 5.99 0.1 5.00
94 INT293958 Gene_expression of PION 1 0.49 1.69 0.06 5.00
95 INT274075 Positive_regulation of Gene_expression of Map2k4 1 0.16 4.28 0.04 5.00
96 INT177342 Negative_regulation of SRGN 15 0.28 5.66 0.04 5.00
97 INT202363 Phosphorylation of Map2k4 11 0.79 2.94 0.04 5.00
98 INT318720 Regulation of Binding of Pdss1 1 0.02 0.74 0.04 5.00
99 INT329018 Binding of SRGN 1 0.23 1.21 0.03 5.00
100 INT329019 Negative_regulation of Binding of SRGN 1 0.28 1.22 0.03 5.00
101 INT274068 Positive_regulation of Gene_expression of Map3k5 1 0.53 2.85 0.03 5.00
102 INT331894 Localization of SEPT8 1 0.14 0.61 0 5.00
103 INT274073 Negative_regulation of Map3k5 1 0.33 0.28 0 5.00
104 INT329017 Binding of GON4L 1 0.04 0.43 0 5.00
105 INT230372 Negative_regulation of ELL 5 0.03 1.35 0 5.00
106 INT331895 Gene_expression of SEPT4 1 0.27 0.57 0 5.00
107 INT331893 Binding of Sept3 1 0.19 0.59 0 5.00
108 INT331896 Localization of SEPT4 1 0.30 0.14 0 5.00
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