D:Retinal Detachment

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Disease Term
Synonyms Detachment Retinal, Detachments Retinal, Retinal Detachments, Retinal Pigment Epithelial Detachment
Documents 50
Hot Single Events 8
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Retinal Detachment. They are ordered first by their relevance to Retinal Detachment and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT340505 Binding of Twist1 and Mgat4b 1 0.01 0.45 0.08 48.16
2 INT211492 Positive_regulation of GRIN1 Positive_regulation of Prkca 1 0.01 0.87 0.36 5.00
3 INT259023 CADPS Positive_regulation of Binding of SH2B2 1 0.06 2.05 0.14 5.00
4 INT243233 Positive_regulation of Ighmbp2 Negative_regulation of Rs1 1 0.11 0.31 0 5.00
5 INT243235 Ighmbp2 Negative_regulation of Rs1 1 0.11 0.31 0 5.00
6 INT243232 Ighmbp2 Negative_regulation of Ptch1 1 0.02 0.22 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Retinal Detachment. They are ordered first by their pain relevance and then by number of times they were reported in Retinal Detachment. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT146024 Negative_regulation of Ped 4 0.16 3.06 1.12 99.86
2 INT297602 Positive_regulation of Tsv 3 0.07 3.36 0.33 98.60
3 INT13556 Gene_expression of CD4 367 0.78 230.82 41.74 92.64
4 INT96533 Gene_expression of Slc1a3 72 0.78 26.85 55.31 91.52
5 INT74826 Gene_expression of Slc1a2 131 0.78 61.83 100.84 89.08
6 INT260525 Gene_expression of AMD1 25 0.66 24.58 1.32 86.24
7 INT99538 Gene_expression of Slc1a1 26 0.75 9.3 21.57 86.16
8 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 84.16
9 INT60766 Gene_expression of COL4A4 10 0.77 13.46 1.14 78.88
10 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73 78.52
11 INT23045 Positive_regulation of Hbb 31 0.64 19.35 4.54 77.68
12 INT243226 Positive_regulation of Rs1 3 0.70 5.6 0.31 72.88
13 INT243221 Positive_regulation of Localization of Xmmv63 1 0.49 1.19 0.04 72.88
14 INT243230 Positive_regulation of Localization of Rs1 1 0.44 1.18 0.04 72.88
15 INT243231 Localization of Rs1 2 0.67 2.15 0.1 72.60
16 INT243229 Localization of Xmmv63 1 0.73 1.18 0.04 72.36
17 INT211489 Gene_expression of ARHGAP4 6 0.65 2.88 0.61 69.12
18 INT211491 Positive_regulation of Gene_expression of ARHGAP4 1 0.49 1.18 0.29 69.12
19 INT272415 Negative_regulation of Gene_expression of NARFL 14 0.34 17.62 0.73 65.60
20 INT272273 Gene_expression of NARFL 89 0.54 121.19 4.47 63.00
21 INT243225 Binding of Rs1 2 0.33 1.32 0.03 58.28
22 INT79395 Gene_expression of Twist1 193 0.77 100.06 26.34 56.80
23 INT10873 Localization of Twist1 21 0.74 10.43 1.37 56.40
24 INT39153 Positive_regulation of PTGS2 182 0.70 96.16 60.6 55.24
25 INT1982 Regulation of NARFL 119 0.49 116.2 14.35 51.76
26 INT99688 Negative_regulation of Gene_expression of VEGFA 274 0.58 201.8 31.1 50.76
27 INT243222 Gene_expression of Rs1 6 0.78 8.49 0.17 49.16
28 INT43820 Positive_regulation of Twist1 75 0.59 42.15 8.47 44.92
29 INT202939 Regulation of AMD1 4 0.38 2.68 0 39.12
30 INT94165 Negative_regulation of RB1 30 0.52 27.29 0.51 36.16
31 INT48692 Binding of VEGFA 345 0.48 210.3 21.31 34.64
32 INT50016 Positive_regulation of ARHGAP4 3 0.49 1.8 0.58 29.44
33 INT80124 Negative_regulation of VEGFA 450 0.58 311.19 44.53 25.60
34 INT1981 Negative_regulation of NARFL 219 0.47 223.48 16.41 13.92
35 INT99539 Positive_regulation of Slc1a2 25 0.67 5.46 23.38 12.92
36 INT17401 Gene_expression of IGF1 475 0.78 232.18 62.07 8.32
37 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 5.00
38 INT9987 Gene_expression of Abat 296 0.78 95.46 226.34 5.00
39 INT2391 Negative_regulation of PTGS1 501 0.59 207.62 205.6 5.00
40 INT5116 Gene_expression of IL2 670 0.78 291.13 146.69 5.00
41 INT9235 Negative_regulation of Gene_expression of TNF 346 0.59 252.98 118.61 5.00
42 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65 5.00
43 INT14049 Positive_regulation of GRIN1 102 0.70 48.31 71.06 5.00
44 INT4216 Gene_expression of CD40LG 328 0.78 256.02 44.23 5.00
45 INT935 Localization of Gtf3a 124 0.70 35.72 43.3 5.00
46 INT101992 Localization of VEGFA 413 0.81 258.23 36.15 5.00
47 INT48693 Regulation of VEGFA 268 0.62 191.88 31.52 5.00
48 INT5117 Negative_regulation of Gene_expression of IL2 118 0.59 52.33 29.96 5.00
49 INT3777 Positive_regulation of NARFL 256 0.56 302.43 25.74 5.00
50 INT5328 Positive_regulation of CD4 191 0.69 133.43 21.31 5.00
51 INT2006 Gene_expression of fc 104 0.34 64.91 19.08 5.00
52 INT78024 Gene_expression of ACLY 73 0.75 59.15 18.54 5.00
53 INT18010 Positive_regulation of CD40LG 122 0.70 100.8 18.46 5.00
54 INT49975 Binding of SLC6A3 34 0.47 9.86 12.41 5.00
55 INT182574 Localization of Slc1a3 10 0.73 5.47 11.44 5.00
56 INT10874 Negative_regulation of Twist1 89 0.50 36.84 11.32 5.00
57 INT62919 Regulation of Gnas 22 0.43 5.61 9.55 5.00
58 INT59165 Binding of fc 67 0.36 37.51 8.68 5.00
59 INT22383 Binding of IL2 59 0.48 39.06 8.56 5.00
60 INT17501 Negative_regulation of F2 70 0.58 32.23 7.51 5.00
61 INT35584 Binding of ACLY 22 0.35 31.78 7.17 5.00
62 INT8683 Positive_regulation of F3 31 0.67 42.89 6.21 5.00
63 INT223568 Gene_expression of GYPE 21 0.65 5.83 6.12 5.00
64 INT102836 Binding of LRP2 12 0.38 11.27 5.58 5.00
65 INT111055 Localization of Slc1a2 4 0.71 2.04 4.41 5.00
66 INT102187 Gene_expression of SH2B2 23 0.59 26.54 4.39 5.00
67 INT19449 Binding of FANCB 22 0.47 7.4 4.27 5.00
68 INT173910 Gene_expression of LRP2 24 0.75 19.99 4.09 5.00
69 INT87517 Gene_expression of LDLR 73 0.69 37.35 3.32 5.00
70 INT132239 Localization of Slc1a1 4 0.77 1.93 3.27 5.00
71 INT175262 Binding of SH2B2 18 0.36 22.85 3.18 5.00
72 INT77670 Positive_regulation of ACLY 24 0.49 21.68 3.12 5.00
73 INT61791 Positive_regulation of SH2B2 9 0.50 8.36 2.99 5.00
74 INT116540 Binding of Twist1 35 0.48 16.32 2.85 5.00
75 INT4114 Gene_expression of Srf 9 0.70 6.11 2.63 5.00
76 INT113164 Regulation of Regulation of VEGFA 6 0.36 5.96 2.43 5.00
77 INT209501 Gene_expression of CADPS 15 0.65 20.7 2.22 5.00
78 INT11183 Negative_regulation of SH2B2 4 0.34 6.99 2.12 5.00
79 INT262364 Positive_regulation of LRP2 6 0.39 4.44 1.97 5.00
80 INT92774 Gene_expression of PVALB 3 0.37 3.47 1.63 5.00
81 INT17885 Negative_regulation of YWHAZ 6 0.56 2.74 1.58 5.00
82 INT185649 Regulation of ERG 17 0.20 10.14 1.49 5.00
83 INT12035 Regulation of F2 21 0.45 12.66 1.47 5.00
84 INT259036 Transcription of SH2B2 2 0.55 7.01 1.46 5.00
85 INT114808 Positive_regulation of Binding of SLC6A3 4 0.50 0.63 1.45 5.00
86 INT181868 Localization of ACLY 5 0.62 6.36 1.4 5.00
87 INT24519 Negative_regulation of ERG 15 0.38 6.98 1.33 5.00
88 INT236277 Positive_regulation of Gene_expression of CADPS 5 0.42 9.17 1.29 5.00
89 INT15896 Gene_expression of FANCB 18 0.65 6.44 1.18 5.00
90 INT209503 Positive_regulation of CADPS 3 0.42 7 1.11 5.00
91 INT158651 Gene_expression of Plxna2 9 0.66 1.98 0.98 5.00
92 INT39369 Binding of NARFL 14 0.29 16.7 0.93 5.00
93 INT92778 Negative_regulation of Gene_expression of PVALB 2 0.24 1.71 0.92 5.00
94 INT211488 Regulation of Binding of VEGFA 5 0.43 3.72 0.83 5.00
95 INT202940 Binding of AMD1 13 0.41 16.43 0.56 5.00
96 INT52740 Binding of ACLS 5 0.31 3 0.54 5.00
97 INT211487 Gene_expression of Slc1a6 1 0.17 0.3 0.54 5.00
98 INT9020 Binding of Tsv 2 0.25 1.28 0.48 5.00
99 INT200435 Binding of polymerase 6 0.16 5.56 0.47 5.00
100 INT259035 Localization of SH2B2 3 0.43 1.77 0.42 5.00
101 INT259031 Negative_regulation of Gene_expression of CADPS 1 0.07 3.04 0.35 5.00
102 INT243843 Negative_regulation of FMT 3 0.07 1.4 0.32 5.00
103 INT18821 Positive_regulation of Gene_expression of Srf 2 0.35 0.63 0.31 5.00
104 INT269748 Positive_regulation of AMD1 4 0.43 3.56 0.28 5.00
105 INT7610 Localization of Srf 3 0.67 0.98 0.27 5.00
106 INT17009 Regulation of CADPS 2 0.08 1.97 0.24 5.00
107 INT175260 Negative_regulation of Gene_expression of SH2B2 2 0.25 4.41 0.21 5.00
108 INT157725 Gene_expression of ACLS 2 0.13 2.89 0.17 5.00
109 INT243842 Localization of FMT 2 0.11 1.17 0.17 5.00
110 INT259033 Gene_expression of LCA5L 1 0.01 2.71 0.16 5.00
111 INT259032 Binding of PEX1 2 0.01 4.67 0.15 5.00
112 INT5433 Regulation of polymerase 8 0.03 4.2 0.15 5.00
113 INT259037 Negative_regulation of Binding of ACLY 1 0.07 1.54 0.13 5.00
114 INT243228 Protein_catabolism of Ighmbp2 3 0.16 0.83 0.1 5.00
115 INT259038 Negative_regulation of Positive_regulation of SH2B2 1 0.25 1.83 0.09 5.00
116 INT259039 Positive_regulation of Binding of ACLY 1 0.09 1.85 0.09 5.00
117 INT185394 Binding of PVRL1 5 0.14 2.94 0.09 5.00
118 INT259030 Negative_regulation of Gene_expression of ACLY 1 0.07 1.95 0.08 5.00
119 INT273763 Gene_expression of PSMB5 1 0.65 0.36 0.06 5.00
120 INT346651 Gene_expression of Tsv 1 0.10 0.59 0.06 5.00
121 INT260527 Negative_regulation of AMD1 6 0.37 5 0.05 5.00
122 INT259040 Phosphorylation of SH2B2 1 0.47 0.85 0.03 5.00
123 INT259029 Regulation of Phosphorylation of SH2B2 1 0.26 0.85 0.03 5.00
124 INT243224 Regulation of Plxna2 2 0.13 1.58 0 5.00
125 INT212586 Phosphorylation of polymerase 3 0.08 2.64 0 5.00
126 INT243223 Negative_regulation of Rs1 1 0.43 1.3 0 5.00
127 INT243227 Transcription of Rs1 1 0.69 1.79 0 5.00
128 INT308254 Negative_regulation of Binding of PVRL1 1 0.01 1.02 0 5.00
129 INT243220 Binding of Plxna2 1 0.06 0.87 0 5.00
130 INT308253 Regulation of Phosphorylation of polymerase 1 0.01 1.19 0 5.00
131 INT259024 Regulation of Anxa5 1 0.44 1.25 0 5.00
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