D:Retinal Dystrophies

From wiki-pain
Jump to: navigation, search

pChart

Disease Term
Synonyms Dystrophies Retinal, Dystrophy Retinal, Retinal Dystrophy
Documents 17
Hot Single Events 5
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Retinal Dystrophies. They are ordered first by their relevance to Retinal Dystrophies and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT233397 Binding of ABCA4 and COL2A1 1 0.38 3.59 0.03 19.92
2 INT227399 Binding of D5Mit424 and Alms1 1 0.01 0.71 0 14.32
3 INT227398 Binding of H2afy and Alms1 1 0.01 1.42 0 14.32
4 INT212139 Slc4a3 Positive_regulation of Cl 1 0.07 0 0.12 5.00
5 INT212138 Slc4a3 Positive_regulation of Gene_expression of Cl 1 0.07 0 0.12 5.00
6 INT200761 Binding of Tfam and Gopc 1 0.01 0.1 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Retinal Dystrophies. They are ordered first by their pain relevance and then by number of times they were reported in Retinal Dystrophies. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT85640 Gene_expression of Tg(CAG-EGFP)D4Nagy 1138 0.72 311.58 119.18 99.56
2 INT169778 Positive_regulation of Opn4 8 0.68 1.63 0.63 99.40
3 INT233399 Binding of ABCA4 9 0.46 9.49 0.07 99.16
4 INT205040 Gene_expression of CLTA 7 0.19 7.64 0.25 90.88
5 INT192791 Negative_regulation of MVK 3 0.16 5.64 0.25 83.76
6 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 71.36
7 INT24225 Gene_expression of Alms1 93 0.62 52.75 16.93 71.28
8 INT11659 Gene_expression of COL2A1 164 0.78 78.49 22.58 70.24
9 INT197512 Gene_expression of ABCA4 19 0.75 7.08 0.57 70.24
10 INT117232 Localization of COL2A1 11 0.72 7.34 1.3 69.64
11 INT197511 Localization of ABCA4 3 0.68 1.47 0.03 69.64
12 INT72334 Negative_regulation of LRP5 7 0.35 1.71 0.81 69.04
13 INT212140 Gene_expression of CA14 1 0.11 1.66 0.06 68.72
14 INT176609 Gene_expression of Dpep1 8 0.03 2.37 1.07 68.36
15 INT158124 Gene_expression of COL5A2 136 0.69 72.3 12.44 65.96
16 INT82866 Localization of Atp9a 13 0.78 6.95 1.56 59.32
17 INT216110 Binding of AAVS1 13 0.36 3.24 0.3 59.32
18 INT61684 Localization of COL1A2 20 0.73 9.31 2.26 59.16
19 INT243453 Negative_regulation of Opn4 13 0.50 2.37 0.09 53.60
20 INT105670 Gene_expression of AAVS1 131 0.75 49.24 12.95 51.04
21 INT10373 Gene_expression of ADI1 8 0.25 5.97 0.92 50.84
22 INT192537 Gene_expression of AIPL1 2 0.42 1.36 0 49.92
23 INT209418 Negative_regulation of CLTA 2 0.06 1.62 0.03 41.68
24 INT113806 Transcription of CYP2B6 7 0.67 1.75 1.73 38.08
25 INT177551 Negative_regulation of Tg(CAG-EGFP)D4Nagy 31 0.37 11.16 2.65 36.88
26 INT200752 Negative_regulation of Tfam 1 0.13 0.3 0.03 36.88
27 INT200756 Gene_expression of Tfam 8 0.51 0.65 0.03 31.36
28 INT155033 Gene_expression of Phlda2 18 0.30 9.45 0.5 21.48
29 INT96693 Binding of COL2A1 45 0.46 37.11 2.61 19.92
30 INT212125 Regulation of Gene_expression of Cl 2 0.06 1.88 1.05 13.04
31 INT212124 Gene_expression of Cl 18 0.11 6.72 1.93 12.80
32 INT188168 Binding of Slc4a3 4 0.47 1.06 0.07 9.40
33 INT212142 Binding of CA14 1 0.08 0 0 9.24
34 INT125391 Gene_expression of Rim5 2 0.01 1.94 0.11 6.32
35 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 5.00
36 INT6852 Localization of TNF 883 0.81 705.95 270.84 5.00
37 INT120811 Gene_expression of Gopc 1174 0.59 428.49 150.55 5.00
38 INT92669 Gene_expression of Bdnf 309 0.78 178.26 116.68 5.00
39 INT30170 Gene_expression of Car2 330 0.66 77.26 46.76 5.00
40 INT3987 Positive_regulation of IGHE 316 0.70 283.2 40.16 5.00
41 INT10796 Gene_expression of CYP2B6 131 0.77 30.14 35.27 5.00
42 INT66200 Gene_expression of Gfap 215 0.78 88.04 28.25 5.00
43 INT111401 Positive_regulation of Gene_expression of Tg(CAG-EGFP)D4Nagy 134 0.61 34.87 20.15 5.00
44 INT12922 Gene_expression of Atp9a 115 0.75 50.95 17.01 5.00
45 INT14587 Positive_regulation of Cl 44 0.20 20.37 16.72 5.00
46 INT104441 Binding of NOVA2 72 0.42 16.41 10.51 5.00
47 INT148703 Gene_expression of NOVA2 73 0.65 18.05 8.3 5.00
48 INT7813 Regulation of SRI 25 0.61 6.18 8.13 5.00
49 INT11258 Gene_expression of Gnas 58 0.58 21.6 6.33 5.00
50 INT16573 Regulation of Cl 18 0.07 8.69 6.03 5.00
51 INT147263 Regulation of Gene_expression of Tg(CAG-EGFP)D4Nagy 51 0.53 15.32 5.86 5.00
52 INT125534 Regulation of Tg(CAG-EGFP)D4Nagy 31 0.39 13.88 5.58 5.00
53 INT72703 Gene_expression of Ide 79 0.70 45.04 4.47 5.00
54 INT4360 Gene_expression of Hypism 29 0.22 38.1 4.07 5.00
55 INT229153 Gene_expression of Esyt2 12 0.21 2.14 3.76 5.00
56 INT108761 Localization of Alms1 24 0.70 13.92 3.74 5.00
57 INT36142 Negative_regulation of Hmgcr 33 0.46 15.91 3.54 5.00
58 INT53021 Positive_regulation of COL2A1 29 0.55 27.75 3.47 5.00
59 INT181804 Negative_regulation of Gene_expression of Tg(CAG-EGFP)D4Nagy 57 0.50 12.54 3 5.00
60 INT98686 Gene_expression of Calb2 28 0.51 12.07 2.84 5.00
61 INT149125 Gene_expression of Slc4a3 25 0.78 3.45 2.41 5.00
62 INT73266 Gene_expression of RB1 50 0.70 29.09 2.31 5.00
63 INT64777 Negative_regulation of COL5A2 32 0.38 17.4 2.28 5.00
64 INT174541 Positive_regulation of Gene_expression of COL5A2 18 0.36 14.17 2.12 5.00
65 INT173512 Positive_regulation of Gene_expression of Alms1 12 0.44 8.66 1.95 5.00
66 INT39376 Positive_regulation of HK1 6 0.53 2.44 1.49 5.00
67 INT185649 Regulation of ERG 17 0.20 10.14 1.49 5.00
68 INT109536 Negative_regulation of Vegfa 15 0.46 10.35 1.39 5.00
69 INT169776 Gene_expression of Opn4 52 0.77 8.75 1.38 5.00
70 INT268009 Gene_expression of Gpsm2 12 0.54 0.23 1.34 5.00
71 INT192982 Binding of Calb2 8 0.33 1.61 1.22 5.00
72 INT275292 Positive_regulation of Gpsm2 7 0.55 0.33 1.19 5.00
73 INT147909 Gene_expression of Lpl 21 0.58 9.35 1.14 5.00
74 INT182454 Binding of Tg(CAG-EGFP)D4Nagy 28 0.29 3.29 1.11 5.00
75 INT176528 Regulation of Spp1 9 0.45 9.05 0.77 5.00
76 INT212128 Binding of Cl 5 0.11 0.92 0.75 5.00
77 INT200750 Gene_expression of Rho 19 0.65 6.52 0.69 5.00
78 INT280946 Positive_regulation of Sema5b 6 0.05 1.36 0.58 5.00
79 INT200754 Gene_expression of Rpe 35 0.51 6.3 0.58 5.00
80 INT243864 Gene_expression of DLG4 5 0.34 0.22 0.54 5.00
81 INT248207 Positive_regulation of Calb2 3 0.20 0.49 0.46 5.00
82 INT347090 Positive_regulation of Smarcc1 1 0.01 0.56 0.37 5.00
83 INT200757 Gene_expression of Fig4 2 0.20 1.27 0.37 5.00
84 INT45429 Binding of Tfam 3 0.41 0.74 0.33 5.00
85 INT57902 Localization of RHO 3 0.36 0.77 0.31 5.00
86 INT212132 Negative_regulation of Slc4a3 1 0.43 1.17 0.3 5.00
87 INT200760 Positive_regulation of Gene_expression of Fig4 1 0.16 0.96 0.29 5.00
88 INT233398 Localization of TIMP3 2 0.45 1.31 0.26 5.00
89 INT200753 Gene_expression of Ocm 2 0.15 1.6 0.24 5.00
90 INT212127 Positive_regulation of Gene_expression of Slc4a3 1 0.50 0.93 0.23 5.00
91 INT208539 Positive_regulation of Gene_expression of Gnas 4 0.08 2.76 0.18 5.00
92 INT275291 Regulation of Gpsm2 3 0.36 0.43 0.17 5.00
93 INT212136 Positive_regulation of Slc4a3 1 0.70 0.54 0.17 5.00
94 INT183817 Localization of BEST1 6 0.26 5.22 0.16 5.00
95 INT212129 Transcription of Slc4a3 1 0.69 0.07 0.13 5.00
96 INT212135 Localization of Slc4a3 2 0.73 0.35 0.13 5.00
97 INT212131 Positive_regulation of Gene_expression of Cl 4 0.08 0.88 0.12 5.00
98 INT192533 Positive_regulation of CLTA 4 0.13 4.98 0.1 5.00
99 INT212130 Gene_expression of Vsx1 2 0.61 0.1 0.1 5.00
100 INT264282 Positive_regulation of Gene_expression of Opn4 3 0.50 0.25 0.08 5.00
101 INT212126 Gene_expression of Slc4a4 7 0.55 0.19 0.06 5.00
102 INT348907 Negative_regulation of Gpsm2 1 0.18 0 0.05 5.00
103 INT243451 Negative_regulation of Igl 2 0.28 0.12 0.05 5.00
104 INT200759 Positive_regulation of Gene_expression of Rpe 5 0.21 0.88 0.03 5.00
105 INT192540 Binding of CLTA 4 0.09 2.28 0.03 5.00
106 INT212137 Transcription of Slc4a4 1 0.55 0 0 5.00
107 INT334169 Localization of Calb2 2 0.40 0 0 5.00
108 INT348909 Regulation of Igl 1 0.16 0.2 0 5.00
109 INT347093 Gene_expression of Vmn2r122 1 0.05 3.88 0 5.00
110 INT200758 Regulation of Gene_expression of Tfam 1 0.14 0.07 0 5.00
111 INT227397 Localization of Rim5 1 0.02 0.49 0 5.00
112 INT212133 Positive_regulation of Slc4a4 1 0.40 0 0 5.00
113 INT212141 Positive_regulation of Gene_expression of CA14 1 0.08 0.32 0 5.00
114 INT200755 Positive_regulation of Gene_expression of Tfam 1 0.16 0.1 0 5.00
115 INT212134 Regulation of Slc4a3 1 0.62 0.34 0 5.00
116 INT347091 Binding of Opn4 1 0.37 0.48 0 5.00
117 INT200751 Positive_regulation of Binding of Tg(CAG-EGFP)D4Nagy 3 0.33 0.39 0 5.00
118 INT347094 Regulation of Gene_expression of Vmn2r122 1 0.02 0.5 0 5.00
119 INT347092 Positive_regulation of Gene_expression of Vmn2r122 1 0.03 0.55 0 5.00
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox