D:Retinitis

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Disease Term
Synonyms Neuroretinitis
Documents 155
Hot Single Events 37
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Retinitis. They are ordered first by their relevance to Retinitis and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT280569 Binding of GEM and HIVEP1 1 0.00 1.59 0.03 70.80
2 INT280601 Binding of HIVEP1 and Dbi 1 0.00 1.57 0.03 69.56
3 INT333969 Binding of TNF and Cd4 1 0.03 1.28 0.39 5.00
4 INT353454 Binding of BRCA1 and IL17A 1 0.00 2.55 0.36 5.00
5 INT353452 Binding of AGRP and BRCA1 1 0.00 3.89 0.34 5.00
6 INT353448 BRCA1 Positive_regulation of CCL2 1 0.01 1.37 0.26 5.00
7 INT353449 BRCA1 Positive_regulation of IL4 1 0.00 1.37 0.26 5.00
8 INT353455 BRCA1 Positive_regulation of IL13 1 0.00 1.37 0.26 5.00
9 INT177961 Binding of CCR3 and CCL11 1 0.04 0.73 0.26 5.00
10 INT177957 CCL11 Regulation of Binding of IL5 and CCL11 1 0.01 0.71 0.25 5.00
11 INT177960 Binding of IL5 and CCL11 1 0.03 0.71 0.25 5.00
12 INT177962 IL4 Positive_regulation of VCAM1 1 0.02 0.97 0.2 5.00
13 INT268279 Positive_regulation of Binding of Aggf1 and Alms1 1 0.02 0.15 0.18 5.00
14 INT268280 Binding of Aggf1 and Alms1 1 0.01 0.15 0.18 5.00
15 INT353451 Binding of BRCA1 and CRP 1 0.01 1.18 0.14 5.00
16 INT353453 Binding of BRCA1 and IL4 1 0.00 1.18 0.14 5.00
17 INT186860 MIR181A2HG Regulation of Cd86 1 0.02 1.05 0.07 5.00
18 INT186814 MIR181A2HG Regulation of ICAM1 1 0.01 1.05 0.07 5.00
19 INT353450 Binding of BRCA1 and VEGFA 1 0.01 0.82 0.05 5.00
20 INT319111 Binding of Yy1 and Sap30 1 0.01 0 0.04 5.00
21 INT229098 Binding of TP53 and IER3 1 0.01 1.47 0.03 5.00
22 INT280568 MRAS Positive_regulation of RAF1 1 0.01 0.7 0 5.00
23 INT319094 Binding of polymerase and RNPC3 1 0.00 0.13 0 5.00
24 INT280566 Binding of ARAF and BCL2 1 0.02 0.69 0 5.00
25 INT177958 IGHE Positive_regulation of TNF 1 0.03 2.23 0 5.00
26 INT177959 Positive_regulation of IGHE Positive_regulation of TNF 1 0.03 2.23 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Retinitis. They are ordered first by their pain relevance and then by number of times they were reported in Retinitis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT70503 Regulation of Gene_expression of Nos2 71 0.62 44 24.01 99.40
2 INT48955 Gene_expression of Nos2 753 0.78 403.87 208.08 99.12
3 INT255232 Gene_expression of PRNT 1 0.65 1.64 0.13 97.40
4 INT5328 Positive_regulation of CD4 191 0.69 133.43 21.31 95.44
5 INT719 Negative_regulation of SGCG 96 0.57 47.91 30.22 94.88
6 INT20055 Gene_expression of CRTAC1 19 0.58 15.49 4.73 94.72
7 INT1878 Binding of HLA-B 440 0.48 321.16 127.36 94.40
8 INT308254 Negative_regulation of Binding of PVRL1 1 0.01 1.02 0 93.92
9 INT35009 Binding of CSAD 12 0.41 10.74 3.21 93.88
10 INT200435 Binding of polymerase 6 0.16 5.56 0.47 93.12
11 INT185394 Binding of PVRL1 5 0.14 2.94 0.09 93.12
12 INT89966 Negative_regulation of Fas 26 0.58 24.83 3.5 92.96
13 INT107302 Negative_regulation of Gene_expression of Fasl 7 0.42 8.52 2.54 92.96
14 INT133766 Negative_regulation of Fasl 11 0.56 11.28 2.27 92.96
15 INT89967 Negative_regulation of Gene_expression of Fas 19 0.58 19.28 1.1 92.96
16 INT81627 Gene_expression of Fas 120 0.78 115.51 15.36 92.56
17 INT93626 Gene_expression of Fasl 118 0.75 115.24 25.11 92.24
18 INT5841 Gene_expression of Vim 181 0.72 138.54 16.33 92.12
19 INT1124 Negative_regulation of CD40LG 53 0.57 36.26 7 90.24
20 INT48953 Positive_regulation of Nos2 486 0.70 239.85 131.87 88.48
21 INT17565 Regulation of Gpt 85 0.60 43.64 13.68 87.80
22 INT12097 Regulation of GGT1 8 0.44 5.76 1.95 87.80
23 INT48952 Negative_regulation of Nos2 204 0.59 101.73 53.15 87.12
24 INT280587 Negative_regulation of MT1E 1 0.01 2.56 0 86.96
25 INT64636 Positive_regulation of Gene_expression of Nos2 242 0.70 147.52 79.53 86.24
26 INT221269 Binding of BRCA1 14 0.40 31.77 2.7 85.44
27 INT300184 Gene_expression of BMX 1 0.04 0.69 0 83.96
28 INT141665 Gene_expression of AGRP 83 0.67 43.43 4.24 83.76
29 INT66082 Regulation of CSAD 5 0.27 4.72 1.99 82.80
30 INT81628 Positive_regulation of Gene_expression of Fas 32 0.67 38.13 4.23 82.72
31 INT81629 Positive_regulation of Fas 58 0.70 59.63 12.94 82.72
32 INT237258 Binding of Rhbdl1 2 0.37 1.27 0.28 82.68
33 INT13556 Gene_expression of CD4 367 0.78 230.82 41.74 82.52
34 INT93620 Positive_regulation of Gene_expression of Fasl 51 0.66 59.45 12.04 82.40
35 INT99942 Positive_regulation of Fasl 37 0.68 32.61 6.92 82.40
36 INT53532 Gene_expression of Lcp1 10 0.70 11.57 1.69 81.76
37 INT119063 Gene_expression of BRCA1 24 0.67 30.04 4.17 81.68
38 INT45155 Negative_regulation of Polymerase 18 0.51 15.18 1.38 78.08
39 INT78694 Positive_regulation of Gene_expression of Casp3 46 0.66 18.64 19.62 76.72
40 INT31116 Gene_expression of Casp3 192 0.78 78.21 57.43 75.60
41 INT4420 Positive_regulation of GOT1 103 0.64 88.4 18.38 75.00
42 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74 75.00
43 INT237257 Gene_expression of Rhbdl1 3 0.67 5.15 4.31 73.12
44 INT237259 Positive_regulation of Gene_expression of Rhbdl1 1 0.50 3.58 0 73.12
45 INT3952 Negative_regulation of ALB 116 0.59 72.18 18.35 65.16
46 INT30738 Negative_regulation of Gene_expression of ALB 32 0.59 19.01 5.04 65.16
47 INT3758 Gene_expression of ALB 326 0.78 184.65 38.75 64.72
48 INT237256 Positive_regulation of Rhbdl1 6 0.47 4.64 0.78 64.40
49 INT50255 Regulation of Cd4 39 0.49 29.73 6.77 59.76
50 INT163114 Positive_regulation of Gene_expression of GOT1 7 0.24 8.93 0.5 57.36
51 INT4419 Gene_expression of GOT1 20 0.65 22.53 2.53 56.76
52 INT204112 Gene_expression of GEM 43 0.75 38.74 11.23 55.92
53 INT20345 Gene_expression of Dbi 136 0.78 56.41 46.2 53.88
54 INT15515 Positive_regulation of Crp 700 0.70 604.24 150.15 53.60
55 INT3361 Positive_regulation of Esr1 273 0.69 208.53 44.81 52.96
56 INT70850 Positive_regulation of Transcription of Nos2 30 0.70 18.95 9.68 50.76
57 INT61953 Transcription of Nos2 101 0.72 46.64 25.49 50.32
58 INT89784 Regulation of Transcription of Nos2 14 0.42 8.39 4.24 50.32
59 INT212586 Phosphorylation of polymerase 3 0.08 2.64 0 48.88
60 INT308253 Regulation of Phosphorylation of polymerase 1 0.01 1.19 0 48.88
61 INT36287 Binding of CD4 96 0.47 58.93 11.88 46.44
62 INT5433 Regulation of polymerase 8 0.03 4.2 0.15 46.20
63 INT131359 Positive_regulation of Gene_expression of Cd4 40 0.58 22.43 7.53 41.60
64 INT99001 Negative_regulation of Selp 23 0.59 16.68 4.74 41.52
65 INT136325 Negative_regulation of Binding of Selp 2 0.59 2.26 0.42 41.52
66 INT49214 Gene_expression of Cd4 269 0.78 154.22 34.05 41.24
67 INT165213 Regulation of Gene_expression of Cd4 12 0.40 9.14 1.57 41.24
68 INT96084 Binding of Selp 12 0.48 8.41 2.16 41.20
69 INT822 Gene_expression of ESR1 529 0.78 302.16 63.64 40.40
70 INT9660 Regulation of TNF 363 0.62 312.94 139.99 40.12
71 INT25493 Gene_expression of TFPI 74 0.76 39.44 14.78 39.20
72 INT16068 Gene_expression of SERPINB1 27 0.60 20.51 6.56 39.20
73 INT122196 Gene_expression of TAL1 5 0.47 2.07 0.63 39.20
74 INT6852 Localization of TNF 883 0.81 705.95 270.84 32.52
75 INT27096 Positive_regulation of Nfkb1 325 0.70 195.11 109.06 31.04
76 INT172677 Gene_expression of SHE 65 0.59 25.86 3.85 29.60
77 INT23257 Regulation of CRP 127 0.62 100.05 21.87 18.00
78 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 5.00
79 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 5.00
80 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98 5.00
81 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 5.00
82 INT9659 Gene_expression of Il6 991 0.78 715.11 265.57 5.00
83 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97 5.00
84 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 5.00
85 INT6481 Binding of TNF 624 0.48 510.2 214.82 5.00
86 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210 5.00
87 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 5.00
88 INT867 Gene_expression of IFNA1 930 0.78 594.85 168.03 5.00
89 INT55879 Gene_expression of CCL2 421 0.78 240.74 166.02 5.00
90 INT65600 Positive_regulation of Casp3 376 0.70 198.44 128.03 5.00
91 INT8243 Positive_regulation of Il6 451 0.70 358.24 119.28 5.00
92 INT17612 Gene_expression of CRP 676 0.78 580.61 119.03 5.00
93 INT11051 Positive_regulation of Gene_expression of IL6 415 0.69 319.21 109.3 5.00
94 INT60526 Gene_expression of IL10 449 0.78 292.71 107.84 5.00
95 INT12082 Localization of IL6 365 0.81 241.78 105.78 5.00
96 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 5.00
97 INT11587 Gene_expression of CSF2 645 0.78 544.38 93.89 5.00
98 INT48408 Gene_expression of ICAM1 494 0.78 340.08 88.6 5.00
99 INT5056 Gene_expression of IFNG 216 0.78 137.52 74.57 5.00
100 INT1724 Negative_regulation of ACE 437 0.59 315.64 74.48 5.00
101 INT56298 Gene_expression of IL4 306 0.78 182.18 72.92 5.00
102 INT170332 Gene_expression of IFN1@ 477 0.75 275.21 69.65 5.00
103 INT3375 Gene_expression of IGHE 535 0.77 387.47 65.46 5.00
104 INT67981 Positive_regulation of CCL2 165 0.70 136.84 61.85 5.00
105 INT11318 Gene_expression of Gtf3a 274 0.52 183.82 60.89 5.00
106 INT5058 Positive_regulation of IFNA1 356 0.70 245.75 60.52 5.00
107 INT17564 Gene_expression of Gpt 322 0.75 208.51 60.36 5.00
108 INT546 Binding of ALB 311 0.48 85.98 60.14 5.00
109 INT4509 Gene_expression of IgG 426 0.76 293.69 56.64 5.00
110 INT49017 Negative_regulation of Gene_expression of Nos2 169 0.59 80.64 52.67 5.00
111 INT52264 Gene_expression of IK 180 0.77 90.87 51.87 5.00
112 INT6473 Positive_regulation of Gene_expression of IL1B 204 0.70 117.23 50.86 5.00
113 INT22454 Regulation of Crp 213 0.62 160.67 49.24 5.00
114 INT145266 Gene_expression of IL17A 154 0.75 109.83 45.33 5.00
115 INT81498 Positive_regulation of Gene_expression of CCL2 107 0.70 53.89 45.22 5.00
116 INT80124 Negative_regulation of VEGFA 450 0.58 311.19 44.53 5.00
117 INT2774 Binding of Crp 241 0.48 195.89 44.39 5.00
118 INT4216 Gene_expression of CD40LG 328 0.78 256.02 44.23 5.00
119 INT73502 Positive_regulation of IL10 154 0.69 124.87 43.5 5.00
120 INT25383 Gene_expression of Csf2 222 0.76 152.93 43.32 5.00
121 INT52531 Gene_expression of Nfkb1 153 0.75 82.84 42.9 5.00
122 INT4004 Gene_expression of IGHG3 321 0.71 221.03 42.33 5.00
123 INT52732 Negative_regulation of CRP 169 0.59 138.47 40.33 5.00
124 INT3987 Positive_regulation of IGHE 316 0.70 283.2 40.16 5.00
125 INT77307 Gene_expression of Bcl2 399 0.77 319.77 38 5.00
126 INT63349 Gene_expression of PECAM1 199 0.75 166.03 36.76 5.00
127 INT9082 Positive_regulation of ESR1 238 0.69 148.51 36.69 5.00
128 INT101992 Localization of VEGFA 413 0.81 258.23 36.15 5.00
129 INT59466 Gene_expression of ISYNA1 204 0.77 112.57 35.48 5.00
130 INT72651 Gene_expression of TH1L 114 0.75 80.15 35.15 5.00
131 INT9694 Positive_regulation of Csf2 102 0.68 70.09 33.07 5.00
132 INT10248 Gene_expression of KRT20 436 0.78 231.96 32.88 5.00
133 INT6302 Binding of IFNA1 196 0.48 133.85 32.73 5.00
134 INT5989 Positive_regulation of Dbi 79 0.49 24.38 32.56 5.00
135 INT73498 Gene_expression of IL13 117 0.44 83.85 32.26 5.00
136 INT73982 Gene_expression of Hmox1 141 0.78 119.43 32.17 5.00
137 INT7538 Negative_regulation of IL2 95 0.57 47.31 31.7 5.00
138 INT35406 Localization of Tnf 94 0.81 64.63 31.65 5.00
139 INT65960 Gene_expression of BCL2 352 0.78 312.03 30.73 5.00
140 INT34729 Positive_regulation of IFN1@ 233 0.67 128.04 30.38 5.00
141 INT10915 Gene_expression of ITGAM 164 0.78 92.42 29.78 5.00
142 INT37296 Binding of Esr1 117 0.43 62.51 27.33 5.00
143 INT69157 Gene_expression of IL5 127 0.77 102.58 26.81 5.00
144 INT19856 Gene_expression of CD8A 240 0.75 147.86 26.39 5.00
145 INT130176 Positive_regulation of Gene_expression of CRP 125 0.66 137.06 25.9 5.00
146 INT70048 Positive_regulation of Gene_expression of IL10 90 0.55 71.34 25.66 5.00
147 INT55583 Localization of IFNA1 135 0.78 85.07 24.13 5.00
148 INT4781 Gene_expression of TH 68 0.73 26.92 24.01 5.00
149 INT93738 Gene_expression of Tnfrsf1a 63 0.74 57.66 23.09 5.00
150 INT5055 Positive_regulation of IFNG 89 0.69 64.03 23.05 5.00
151 INT69322 Negative_regulation of MAPK14 70 0.54 42.92 22.71 5.00
152 INT48692 Binding of VEGFA 345 0.48 210.3 21.31 5.00
153 INT11157 Binding of EGF 88 0.48 53.73 21.25 5.00
154 INT28216 Gene_expression of HRAS 173 0.75 93.97 20.78 5.00
155 INT63340 Positive_regulation of Gene_expression of ICAM1 109 0.70 90.82 20.61 5.00
156 INT62042 Positive_regulation of Gene_expression of IL4 67 0.56 42.05 20.39 5.00
157 INT57257 Gene_expression of IL7 69 0.62 50.24 20.36 5.00
158 INT14701 Negative_regulation of IFNA1 118 0.54 84.19 20.08 5.00
159 INT192409 Positive_regulation of Gene_expression of IFN1@ 102 0.67 64.66 18.8 5.00
160 INT56301 Positive_regulation of IL4 68 0.56 54.51 18.65 5.00
161 INT18010 Positive_regulation of CD40LG 122 0.70 100.8 18.46 5.00
162 INT116978 Gene_expression of CCR6 53 0.78 56 17.73 5.00
163 INT62826 Negative_regulation of Gene_expression of ICAM1 75 0.58 46.39 17.72 5.00
164 INT2120 Gene_expression of CD79A 159 0.78 111.69 17.16 5.00
165 INT25223 Positive_regulation of Gene_expression of IFNG 41 0.67 36.97 15.89 5.00
166 INT153776 Positive_regulation of IL17A 42 0.64 34.58 14.82 5.00
167 INT11340 Positive_regulation of SLC17A5 120 0.67 113.52 14.5 5.00
168 INT11762 Regulation of Dbi 40 0.62 7.83 14.48 5.00
169 INT20665 Gene_expression of ACE 87 0.78 51.71 14.19 5.00
170 INT17035 Positive_regulation of TFPI 55 0.61 34.88 14.18 5.00
171 INT3796 Gene_expression of Ighm 130 0.77 69.61 13.78 5.00
172 INT52905 Gene_expression of Cd4 84 0.78 45.68 12.75 5.00
173 INT27268 Localization of Gtf3a 71 0.21 56.93 12.51 5.00
174 INT69158 Localization of IL4 48 0.71 31.3 11.98 5.00
175 INT3699 Gene_expression of H2-Ab1 24 0.74 12.06 11.82 5.00
176 INT81640 Positive_regulation of Gene_expression of Bcl2 106 0.69 84.58 11.63 5.00
177 INT102272 Regulation of TH1L 41 0.44 30.89 11.63 5.00
178 INT69029 Gene_expression of PTPRC 127 0.75 74.26 11.57 5.00
179 INT65713 Localization of ICAM1 42 0.81 39.55 11.49 5.00
180 INT72221 Localization of PRKCA 17 0.81 1.23 11.47 5.00
181 INT17349 Negative_regulation of Akr1b1 41 0.59 27.03 10.65 5.00
182 INT58904 Localization of TH1L 40 0.68 27.11 10.52 5.00
183 INT69306 Negative_regulation of TH1L 28 0.57 24.81 9.74 5.00
184 INT3988 Positive_regulation of Gene_expression of IGHE 98 0.68 91.46 9.61 5.00
185 INT5512 Negative_regulation of Dbi 32 0.36 7.33 9.1 5.00
186 INT25381 Localization of Csf2 62 0.76 47.48 9.03 5.00
187 INT111133 Negative_regulation of Mapk3 31 0.57 10.89 8.9 5.00
188 INT8903 Gene_expression of IFNA2 58 0.71 38.23 8.68 5.00
189 INT19185 Negative_regulation of Cd4 80 0.51 61.32 8.51 5.00
190 INT70896 Gene_expression of PDGFB 48 0.65 33.55 8.39 5.00
191 INT25392 Positive_regulation of Gene_expression of Csf2 41 0.49 34.28 8.36 5.00
192 INT13085 Positive_regulation of ACE 50 0.70 44.2 8.31 5.00
193 INT65959 Positive_regulation of Gene_expression of BCL2 75 0.70 77.3 8.27 5.00
194 INT69160 Positive_regulation of IL5 41 0.65 36.04 7.75 5.00
195 INT77306 Negative_regulation of Gene_expression of Bcl2 46 0.58 38.05 7.71 5.00
196 INT18524 Regulation of Gene_expression of IFNA1 37 0.44 18.79 7.62 5.00
197 INT153300 Negative_regulation of Gene_expression of CRP 48 0.58 39.97 7.58 5.00
198 INT157959 Binding of AQP4 32 0.48 43.44 7.44 5.00
199 INT91667 Localization of IL12A 39 0.74 25.51 7.36 5.00
200 INT96994 Phosphorylation of EGFR 99 0.82 52.75 7.33 5.00
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