D:Retinoblastoma

From wiki-pain
Jump to: navigation, search

pChart

Disease Term
Synonyms Familial Retinoblastoma, FAMILIAL RETINOBLASTOMAS, Glioblastoma Retinal, Glioblastomas Retinal, Glioma Retinal, Gliomas Retinal, HEREDITARY RETINOBLASTOMA, Hereditary Retinoblastomas, Neuroblastoma Retinal, NEUROBLASTOMAS RETINAL, RETINAL GLIOBLASTOMA
Documents 190
Hot Single Events 200
Hot Interactions 68

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Retinoblastoma. They are ordered first by their relevance to Retinoblastoma and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT330696 Phosphorylation of RB1 Positive_regulation of Gene_expression of E2F2 1 0.01 1 0 100.00
2 INT94159 Positive_regulation of CDK1 Negative_regulation of RB1 1 0.45 0.93 0.03 100.00
3 INT94157 CDCP1 Negative_regulation of RB1 1 0.02 0.92 0.03 100.00
4 INT94158 CDK1 Negative_regulation of RB1 1 0.41 0.92 0.03 100.00
5 INT196961 Binding of Hmga2 and Rb1 1 0.48 6.47 0 100.00
6 INT330698 PCNA Regulation of RB1 1 0.00 0.3 0 100.00
7 INT255258 Binding of Rb1 and Tsp1 1 0.38 0.95 0.15 100.00
8 INT116107 CDK4 Positive_regulation of Phosphorylation of EID1 1 0.01 0.32 0.86 100.00
9 INT238392 RB1 Regulation of E2F2 1 0.01 0.36 0.08 100.00
10 INT255255 Binding of Nsg1 and Tsp1 1 0.08 0.48 0.08 100.00
11 INT255256 Positive_regulation of Binding of Rb1 and Tsp1 1 0.50 0.48 0.08 100.00
12 INT238397 EID1 Regulation of E2F2 1 0.00 0.36 0.08 100.00
13 INT305542 Binding of Rb1 and Trp53 1 0.00 0.9 0 100.00
14 INT305540 Binding of Trp53 and Tpt1 1 0.07 0.9 0 100.00
15 INT305539 Binding of Mki67 and Trp53 1 0.20 0.91 0 100.00
16 INT305543 Binding of Top2a and Trp53 1 0.37 0.91 0 100.00
17 INT247427 CDKN2A Negative_regulation of Negative_regulation of RB1 1 0.07 1.16 0 99.92
18 INT305541 Binding of Bcl2 and Trp53 1 0.05 0.9 0 99.92
19 INT330697 PCNA Regulation of INCENP 1 0.00 0.3 0 99.36
20 INT298828 Binding of PPARA and Lpl 1 0.05 0.77 0.11 98.08
21 INT354833 Csf2 Positive_regulation of Cd8a 1 0.01 0.98 0 97.92
22 INT172977 Cdkn1a Negative_regulation of Positive_regulation of Inca1 1 0.00 1.39 0.27 97.88
23 INT116108 VEGFA Positive_regulation of SEC23IP 1 0.10 0.3 0.83 97.56
24 INT116109 VEGFA Positive_regulation of PTK2 1 0.13 0.3 0.83 97.56
25 INT116106 VEGFA Positive_regulation of AKT1 1 0.12 0.3 0.83 97.56
26 INT225229 Binding of Cdk6 and Cdkn2a 1 0.19 1.25 0 97.36
27 INT229007 MIA3 Positive_regulation of Gene_expression of Ccnd1 1 0.01 0.55 0 97.20
28 INT225228 Binding of Cdk4 and Cdkn2a 1 0.21 1.24 0 97.00
29 INT302159 TSC1 Positive_regulation of Transcription of CDKN1A 1 0.00 0.28 0.03 96.96
30 INT302134 TP53 Positive_regulation of Transcription of CDKN1A 1 0.04 0.28 0.03 96.96
31 INT196434 Binding of Ccne2 and Cdc25a 1 0.01 0.48 0 96.52
32 INT178443 Negative_regulation of Mapk8 Positive_regulation of Negative_regulation of Mapk14 1 0.13 0.76 0.04 96.16
33 INT172975 Trp53 Positive_regulation of Cdkn1a 1 0.03 1.35 0.26 95.36
34 INT185279 Binding of CCND1 and CDK4 4 0.13 2.05 0.08 94.96
35 INT185278 Binding of CCND1 and CDK6 3 0.13 1.62 0.08 94.96
36 INT185277 CDK6 Negative_regulation of Binding of CDK4 and CDK6 1 0.20 0.87 0 93.76
37 INT185280 Binding of CDK4 and CDK6 1 0.20 0.87 0 93.76
38 INT185276 CDK4 Negative_regulation of Binding of CDK4 and CDK6 1 0.20 0.87 0 93.76
39 INT147593 Binding of CDK4 and CDKN2A 1 0.42 0.23 0.26 92.72
40 INT147592 Positive_regulation of Binding of CDK4 and CDKN2A 1 0.44 0.23 0.26 92.72
41 INT185281 Binding of CDK6 and CDKN2A 1 0.29 0.87 0 91.44
42 INT225158 Binding of CDK2 and CDKN1A 7 0.30 3.26 1.02 90.68
43 INT298000 MAP3K4 Positive_regulation of Gene_expression of Gadd45b 1 0.27 0.72 0.03 88.96
44 INT298001 Gene_expression of Gadd45b Positive_regulation of MAP3K4 1 0.25 0.72 0.03 88.96
45 INT297962 MAP3K4 Positive_regulation of MAPK14 1 0.21 0.66 0.03 88.96
46 INT196955 Binding of E2f1 and Rb1 1 0.36 1 0 88.32
47 INT196944 Binding of Rb1 and Hdac1 1 0.24 0.4 0 88.32
48 INT298002 Gene_expression of Gadd45b Positive_regulation of MAPK14 1 0.29 0.67 0.03 88.24
49 INT298806 Binding of Hdac3 and Rb1 1 0.02 0.77 0.05 87.16
50 INT170858 Binding of IFI27 and Ccne2 1 0.01 0.17 0 85.92
51 INT302146 CDKN2A Regulation of CDKN1B 1 0.11 0.51 0.14 84.96
52 INT302144 CDKN2A Regulation of CDKN1A 1 0.11 0.51 0.14 84.96
53 INT302178 CDKN1C Regulation of CDKN2A 1 0.09 0.26 0.08 84.96
54 INT302158 CDKN1A Regulation of CDKN2A 1 0.04 0.26 0.08 84.96
55 INT302139 LAMTOR1 Regulation of CDKN2A 1 0.08 0.26 0.08 84.96
56 INT302157 MRPL28 Regulation of CDKN2A 1 0.09 0.26 0.08 84.96
57 INT302148 IFI27 Regulation of CDKN2A 1 0.11 0.26 0.08 84.96
58 INT302160 LAMTOR1 Regulation of CDKN1A 1 0.08 0.26 0.06 84.96
59 INT302150 MRPL28 Regulation of CDKN1B 1 0.09 0.26 0.06 84.96
60 INT302136 LAMTOR1 Regulation of CDKN1B 1 0.08 0.26 0.06 84.96
61 INT302127 MRPL28 Regulation of CDKN1A 1 0.09 0.26 0.06 84.96
62 INT302133 IFI27 Regulation of CDKN1B 1 0.11 0.26 0.05 84.96
63 INT302130 CDKN1A Regulation of CDKN1B 1 0.04 0.26 0.05 84.96
64 INT302176 CDKN1C Regulation of CDKN1A 1 0.09 0.26 0.05 84.96
65 INT302141 CDKN1C Regulation of CDKN1B 1 0.09 0.26 0.05 84.96
66 INT302163 IFI27 Regulation of CDKN1A 1 0.11 0.26 0.05 84.96
67 INT252330 Binding of Cd36 and Cd47 2 0.10 0.72 0.19 81.28
68 INT229006 MIA3 Positive_regulation of Phosphorylation of Src 1 0.02 0.44 0.03 80.64
69 INT196950 Binding of Rb1 and E2f2 1 0.01 0.6 0 78.96
70 INT196953 Hmga2 Negative_regulation of Rb1 1 0.59 0.35 0 77.64
71 INT213019 Hdl1 Positive_regulation of Tgoln1 1 0.03 1.01 0.07 75.84
72 INT196943 E2f1 Negative_regulation of Rb1 1 0.42 0.44 0 75.64
73 INT196941 Hdac1 Negative_regulation of Rb1 1 0.27 0.44 0 75.64
74 INT256629 Binding of Ptch1 and Shh 7 0.42 4.22 0.19 75.44
75 INT113844 CDKN1A Negative_regulation of CDK2 4 0.49 1.18 1.27 75.40
76 INT289608 Binding of CDK2 and CCNE2 5 0.06 4.89 0 74.76
77 INT348534 ELMO1 Positive_regulation of RAC1 1 0.02 0.7 0 74.52
78 INT325056 Binding of E2f1 and Ang 1 0.06 1.3 0.12 73.92
79 INT302168 YWHAQ Regulation of TP53 1 0.01 0.41 0.09 73.48
80 INT236936 Ppara Positive_regulation of Mapk1 1 0.09 0.64 0.07 72.72
81 INT325057 Binding of Hand1 and Ang 1 0.01 1.29 0.12 71.84
82 INT255260 Binding of Cd47 and Tsp1 1 0.20 1.42 0.67 70.32
83 INT196964 Binding of E2f1 and Rb1 Negative_regulation of Transcription of E2f1 1 0.46 0.6 0 68.84
84 INT196963 Binding of E2f1 and Rb1 Negative_regulation of E2f1 1 0.46 0.6 0 68.36
85 INT314867 Binding of Cdc7 and Cdkn2b 1 0.25 1.16 0.14 68.24
86 INT314859 Binding of Cdkn2b and Tgfbr3 1 0.33 1.16 0.14 68.24
87 INT314856 Binding of Cdc7 and Cdkn2a 1 0.28 1.34 0.14 67.96
88 INT314852 Binding of Cdkn2a and Tgfbr3 1 0.28 1.15 0.14 67.96
89 INT282286 Akt1 Positive_regulation of Pak1 1 0.15 0.24 0.61 67.36
90 INT196945 Rb1 Negative_regulation of Transcription of E2f1 1 0.42 0.35 0 67.08
91 INT225585 Regulation of Binding of Med1 and Tpr 1 0.00 0.07 0 66.64
92 INT196954 Binding of Atp8a1 and E2f1 1 0.40 0.49 0 66.40
93 INT196946 Binding of E2f1 and Hdac1 1 0.26 0.65 0 66.40
94 INT225583 Binding of Ncoa1 and Tpr 1 0.00 0.07 0 66.20
95 INT225541 Binding of Med1 and Tpr 1 0.00 0.07 0 66.20
96 INT255261 Tsp1 Positive_regulation of Binding of Cd47 1 0.27 0.5 0.23 65.04
97 INT214919 Pkd1 Positive_regulation of CDKN1A 1 0.51 2.6 0 63.48
98 INT196965 Hmga2 Positive_regulation of Binding of Hmga2 and Rb1 1 0.53 0.36 0 62.40
99 INT213031 Positive_regulation of Pik3r1 Positive_regulation of Gene_expression of Nos3 1 0.10 0.8 0.04 61.48
100 INT259051 Binding of TP53 and UBE3A 1 0.01 3.48 0 61.28
101 INT196958 Phosphorylation of Rb1 Positive_regulation of Localization of E2f1 1 0.45 0.44 0 59.56
102 INT213014 Regulation of Hdl1 Positive_regulation of Akt1 1 0.12 0.97 0.05 59.28
103 INT213016 Regulation of Hdl1 Positive_regulation of Pik3r1 1 0.09 0.97 0.05 59.28
104 INT282284 Cpox Positive_regulation of Akt1 1 0.02 0.47 0.54 58.48
105 INT282282 Ptger2 Positive_regulation of Akt1 1 0.03 0.47 0.54 58.08
106 INT220445 Bcl2 Negative_regulation of Positive_regulation of Casp9 1 0.01 1.37 0.03 57.60
107 INT213005 Hdl1 Positive_regulation of Akt1 3 0.19 3.81 0.14 57.44
108 INT213051 Hdl1 Positive_regulation of Pik3r1 1 0.13 1.93 0.09 57.44
109 INT213036 Hdl1 Positive_regulation of Phosphorylation of Mapk14 1 0.22 0.78 0.03 57.28
110 INT96563 Binding of ADRA1D and UCN2 1 0.19 1.34 0.1 57.12
111 INT225623 Negative_regulation of Binding of nr and IGHD6-13 1 0.15 0.05 0 53.48
112 INT225615 Binding of nr and IGHD6-13 1 0.12 0.05 0 53.48
113 INT259050 Binding of HPV18I1 and OPN1LW 1 0.01 1.19 0 52.24
114 INT259049 Binding of BAK1 and HPV18I1 1 0.00 1.19 0 52.24
115 INT322487 PTPN6 Positive_regulation of Binding of CDK2 and CCNE2 1 0.00 0.13 0 51.84
116 INT322546 Negative_regulation of PTPN6 Positive_regulation of Gene_expression of Cdkn1b 1 0.03 0.07 0 48.96
117 INT322545 PTPN6 Positive_regulation of Gene_expression of Cdkn1b 1 0.03 0.07 0 48.96
118 INT314858 Binding of Gdf11 and Ltbp3 1 0.39 0.31 0 47.12
119 INT213023 Hdl1 Regulation of Nos3 2 0.09 4.06 0.09 47.08
120 INT213050 Hdl1 Regulation of Bgn 1 0.00 0.79 0.03 47.08
121 INT213059 Hdl1 Regulation of BGN 1 0.16 0.79 0.03 47.08
122 INT196947 Binding of Rb1 and Positive_regulation of Hmga2 1 0.50 0.3 0 47.04
123 INT172976 Mras Regulation of Gene_expression of Smad4 1 0.00 0.83 0.12 46.92
124 INT88279 Ngf Positive_regulation of Ntrk1 5 0.76 3.06 5.23 43.84
125 INT73538 Ngf Positive_regulation of Ngfr 2 0.41 1.05 0.85 43.84
126 INT201740 Positive_regulation of Ngf Positive_regulation of Nfkb1 1 0.01 1.07 0.51 43.84
127 INT201727 Ngf Positive_regulation of Nfkb1 1 0.01 1 0.48 43.84
128 INT236938 Binding of Akt1 and SPNS1 1 0.00 0.72 0.06 43.76
129 INT225157 CDKN1A Regulation of CHKA 1 0.12 0.58 0 42.28
130 INT178437 Mapk8 Positive_regulation of Jun 3 0.40 2.69 0.58 41.24
131 INT322547 FOXO3 Regulation of Transcription of Cdkn1b 1 0.12 0.32 0 39.12
132 INT322548 FOXO3 Regulation of Cdkn1b 1 0.09 0.23 0 39.12
133 INT282285 Cpox Regulation of Gene_expression of Ptger2 1 0.00 0.84 0.5 37.48
134 INT94331 IFNG Positive_regulation of CXCL10 4 0.11 1.31 0.82 35.92
135 INT213047 Hdl1 Positive_regulation of Gene_expression of Nos3 1 0.14 0.94 0.04 35.84
136 INT322543 Binding of FOXO3 and Cdkn1b 1 0.08 0.84 0.19 35.76
137 INT214917 Pkd1 Positive_regulation of Negative_regulation of CDKN1A 1 0.37 1.46 0 35.04
138 INT225500 Negative_regulation of Ncoa6 Positive_regulation of gr 1 0.09 0 0 32.80
139 INT225575 Ncoa6 Positive_regulation of gr 1 0.10 0 0 32.80
140 INT225618 TARBP2 Positive_regulation of gr 1 0.01 0 0 32.80
141 INT196948 Hmga2 Positive_regulation of Hdac1 1 0.36 0.23 0 32.68
142 INT196959 Hmga2 Positive_regulation of Localization of E2f1 1 0.54 0.24 0 32.68
143 INT225160 Negative_regulation of Binding of CDK2 and CDKN1A 1 0.35 0 0.25 29.48
144 INT314869 Binding of Gdf11 and Tgfbr3 1 0.29 0.14 0 29.12
145 INT314855 Binding of Gdf11 and Atoh7 1 0.40 0.14 0 29.12
146 INT314871 Binding of Tgfbr3 and Atoh7 1 0.33 0.09 0 28.24
147 INT169962 Binding of Rb1 and E2f4 1 0.25 0.56 0.04 27.56
148 INT169960 Binding of Rbl2 and E2f4 1 0.27 1.06 0.04 27.32
149 INT226527 Il1rl1 Positive_regulation of Gene_expression of IK 1 0.00 0.42 0.15 23.72
150 INT241401 VEGFA Positive_regulation of Gene_expression of Gopc 1 0.11 0.85 0.25 23.20
151 INT196956 Binding of Hmga2 and Hdac1 1 0.25 0.23 0 23.08
152 INT213001 Hdl1 Positive_regulation of Trib3 1 0.00 2 0.06 21.76
153 INT213002 Binding of Scarb1 and Trib3 1 0.00 1.02 0.03 21.76
154 INT212938 Binding of Scarb1 and Hdl1 Positive_regulation of Trib3 1 0.00 1.02 0.03 21.76
155 INT338167 Binding of CDKN2A and MC1R 1 0.42 6.14 5.76 21.68
156 INT175700 Nos3 Negative_regulation of smc 1 0.01 1.05 0.59 20.64
157 INT213057 Hdl1 Positive_regulation of Binding of Scarb1 and Hdl1 1 0.08 0.96 0.03 20.32
158 INT213011 Binding of Scarb1 and Hdl1 1 0.13 0.96 0.03 19.60
159 INT325059 Insr Positive_regulation of Ang 1 0.02 1.4 0.08 14.04
160 INT325058 Igf1 Positive_regulation of Ang 1 0.04 1.4 0.08 13.56
161 INT314866 Binding of Six1 and Sall1 1 0.39 0.76 0 12.88
162 INT225516 Ncoa6 Positive_regulation of D0Nrs1 1 0.04 0.3 0 11.96
163 INT225508 Ncoa6 Positive_regulation of Jun 1 0.13 0 0 11.96
164 INT225528 Ncoa6 Positive_regulation of Nfkb1 1 0.08 0 0 11.96
165 INT225527 Ncoa6 Positive_regulation of Creb1 1 0.12 0 0 11.96
166 INT178438 Mapk8 Positive_regulation of Plau 1 0.06 0.52 0.06 10.16
167 INT236937 Map2k1 Negative_regulation of Ppara Positive_regulation of Itk 1 0.00 0.31 0 6.96
168 INT236933 Ppara Positive_regulation of Itk 1 0.01 0.31 0 6.96
169 INT236935 Negative_regulation of Ppara Positive_regulation of Itk 1 0.01 0.31 0 6.96
170 INT69872 Binding of MC1R and POMC 52 0.54 8.87 18.3 5.00
171 INT77646 Binding of Ngf and Ntrk1 23 0.40 7.85 9.26 5.00
172 INT73539 Binding of Ngf and Ngfr 5 0.45 3.99 4 5.00
173 INT69032 IL18 Positive_regulation of IFNA1 12 0.23 7.87 3.83 5.00
174 INT139190 Binding of Fadd and Fas 4 0.38 2.65 1.71 5.00
175 INT127997 Binding of MC1R and RHCE 2 0.28 0.41 1.02 5.00
176 INT226337 Binding of IL10 and IL10RA 2 0.24 2.51 0.85 5.00
177 INT226340 Binding of CD4 and IFNA1 3 0.03 3.84 0.85 5.00
178 INT226371 IL18 Positive_regulation of IL4 4 0.05 2.49 0.79 5.00
179 INT170992 Binding of FN1 and MMRN1 3 0.01 2.13 0.73 5.00
180 INT213026 Hdl1 Positive_regulation of Nos3 5 0.16 7.92 0.73 5.00
181 INT226540 Binding of IL24 and Il20ra 1 0.00 0.97 0.71 5.00
182 INT139901 Ins1 Positive_regulation of Akt1 9 0.31 4.58 0.6 5.00
183 INT190702 CD40 Positive_regulation of Gene_expression of F3 1 0.00 1.4 0.55 5.00
184 INT226360 IL18 Positive_regulation of Gene_expression of IL4 1 0.05 2.66 0.54 5.00
185 INT226348 IL18 Positive_regulation of Gene_expression of IL13 1 0.03 2.66 0.54 5.00
186 INT226517 Binding of IL19 and Il20ra 1 0.00 0.69 0.53 5.00
187 INT285688 Cpox Positive_regulation of PPARA 1 0.02 1 0.5 5.00
188 INT305547 VEGFA Positive_regulation of Gtf3a 2 0.00 1.83 0.48 5.00
189 INT177784 PDCD2 Positive_regulation of ASNS 1 0.04 0.76 0.46 5.00
190 INT125568 Binding of Casr and Ncoa6 3 0.50 1.13 0.46 5.00
191 INT177794 BUB1B Positive_regulation of Gene_expression of ASNS 1 0.11 0.77 0.46 5.00
192 INT177791 PDCD2 Positive_regulation of ATF4 1 0.06 0.76 0.46 5.00
193 INT177781 BUB1B Positive_regulation of ATF4 1 0.07 0.76 0.46 5.00
194 INT177780 BUB1B Positive_regulation of ASNS 1 0.05 0.76 0.46 5.00
195 INT177782 PDCD2 Positive_regulation of MTHFD2 1 0.06 0.76 0.46 5.00
196 INT177787 BUB1B Positive_regulation of MTHFD2 1 0.15 0.76 0.46 5.00
197 INT226341 S1PR1 Regulation of MBTPS1 1 0.00 0.76 0.44 5.00
198 INT213027 Binding of Apoa1 and Scarb1 6 0.09 7.52 0.43 5.00
199 INT226381 S1PR1 Positive_regulation of Gene_expression of IK 1 0.00 0.64 0.38 5.00
200 INT178217 IFNA1 Regulation of Cxcl10 1 0.01 0.86 0.37 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Retinoblastoma. They are ordered first by their pain relevance and then by number of times they were reported in Retinoblastoma. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT94164 Phosphorylation of RB1 83 0.80 48.84 3.21 100.00
2 INT94165 Negative_regulation of RB1 30 0.52 27.29 0.51 100.00
3 INT73266 Gene_expression of RB1 50 0.70 29.09 2.31 100.00
4 INT94168 Positive_regulation of Phosphorylation of RB1 12 0.60 6.6 0.15 100.00
5 INT28215 Gene_expression of CDKN1A 196 0.76 113.9 18.3 100.00
6 INT194993 Binding of RB1 15 0.37 10.96 0.4 100.00
7 INT105330 Gene_expression of CDK2 31 0.63 13.7 0.67 100.00
8 INT78472 Gene_expression of CDKN2A 223 0.78 173.76 13.61 100.00
9 INT22815 Positive_regulation of RB1 20 0.49 14.58 1.26 100.00
10 INT226431 Phosphorylation of INCENP 3 0.04 3.41 0.26 100.00
11 INT94169 Negative_regulation of Phosphorylation of RB1 16 0.41 8.87 1.57 100.00
12 INT63905 Regulation of RB1 13 0.62 12.67 1.28 100.00
13 INT169911 Phosphorylation of Rb1 35 0.73 18.58 0.79 100.00
14 INT169907 Gene_expression of Rb1 25 0.60 21.95 1.32 100.00
15 INT174979 Phosphorylation of GOPC 45 0.51 10.11 2.28 100.00
16 INT57970 Positive_regulation of Rb1 17 0.67 7.03 2.36 100.00
17 INT174197 Negative_regulation of Gene_expression of RB1 4 0.47 4.25 0 100.00
18 INT116114 Phosphorylation of EID1 8 0.12 3.99 1.75 100.00
19 INT94166 Phosphorylation of CDK1 10 0.79 4.75 0.2 100.00
20 INT118955 Phosphorylation of PCNA 4 0.29 1.54 0.33 100.00
21 INT62266 Phosphorylation of Rb1 4 0.71 2.68 0.54 100.00
22 INT75501 Gene_expression of CCND1 90 0.76 60.86 5.93 100.00
23 INT225167 Negative_regulation of Binding of RB1 2 0.34 1.25 0 100.00
24 INT169930 Binding of Rb1 15 0.43 5.91 0.16 100.00
25 INT196426 Gene_expression of Cdkn2b 6 0.67 4.29 0.29 100.00
26 INT80420 Gene_expression of IFI27 145 0.78 63.61 8.83 100.00
27 INT196916 Negative_regulation of Rb1 13 0.42 14.29 0.4 100.00
28 INT297978 Positive_regulation of RBAK 1 0.37 0.75 0.04 100.00
29 INT62269 Gene_expression of Cdkn1a 60 0.73 35.78 9.84 100.00
30 INT99547 Positive_regulation of CDKN1B 18 0.67 8.42 1.96 100.00
31 INT225170 Regulation of Phosphorylation of RB1 2 0.36 1.12 0 100.00
32 INT116112 Negative_regulation of Phosphorylation of EID1 4 0.05 2.65 1.3 100.00
33 INT94161 Negative_regulation of Phosphorylation of CDK1 1 0.41 0.93 0.03 100.00
34 INT94160 Positive_regulation of Phosphorylation of CDK1 2 0.49 0.93 0.03 100.00
35 INT65960 Gene_expression of BCL2 352 0.78 312.03 30.73 100.00
36 INT257732 Regulation of Positive_regulation of RB1 2 0.39 2.35 0.09 100.00
37 INT246285 Gene_expression of Cdkn1c 1 0.03 0.43 0.04 100.00
38 INT41125 Positive_regulation of Localization of Rb1 2 0.38 0.78 0.39 100.00
39 INT935 Localization of Gtf3a 124 0.70 35.72 43.3 100.00
40 INT41126 Localization of Rb1 2 0.61 0.78 0.39 100.00
41 INT77307 Gene_expression of Bcl2 399 0.77 319.77 38 100.00
42 INT62012 Gene_expression of Trafd1 11 0.31 8.53 3.13 100.00
43 INT298778 Phosphorylation of Hdac3 1 0.44 0.67 0.17 100.00
44 INT246232 Gene_expression of Ndrg2 1 0.08 0.65 0 100.00
45 INT251026 Negative_regulation of Phosphorylation of CDKN2A 5 0.42 5.02 0.62 100.00
46 INT251025 Phosphorylation of CDKN2A 4 0.61 3.19 0.32 100.00
47 INT86187 Positive_regulation of AKT1 199 0.69 122.13 19.44 100.00
48 INT41124 Negative_regulation of Rb1 11 0.44 3.17 1.22 100.00
49 INT41123 Positive_regulation of Rb1 12 0.44 3.03 0.73 100.00
50 INT120358 Positive_regulation of Positive_regulation of CDKN1B 2 0.49 1.26 0.55 100.00
51 INT9682 Positive_regulation of IGF1 238 0.70 120.03 26.36 100.00
52 INT125871 Gene_expression of XIAP 5 0.65 11.46 1.46 100.00
53 INT192656 Negative_regulation of EID1 2 0.04 0.93 0.54 100.00
54 INT163035 Gene_expression of E2f1 8 0.71 2.68 0.47 100.00
55 INT197599 Transcription of Rb1 4 0.63 0.87 0.3 100.00
56 INT101620 Gene_expression of TCHP 4 0.02 2.18 0.21 100.00
57 INT191155 Binding of HDAC4 5 0.08 2.79 0.17 100.00
58 INT190563 Regulation of Binding of Rb1 1 0.08 0.7 0.13 100.00
59 INT173175 Phosphorylation of HEPN1 1 0.01 0.71 0.12 100.00
60 INT169940 Positive_regulation of Localization of Rb1 2 0.61 1.74 0.11 100.00
61 INT302301 Binding of EID1 1 0.02 1.1 0.11 100.00
62 INT14446 Binding of TRAFD1 2 0.03 0.93 0.11 100.00
63 INT282707 Positive_regulation of Phosphorylation of EID1 1 0.01 0.53 0.08 100.00
64 INT325054 Positive_regulation of Gene_expression of Trafd1 1 0.01 0.8 0.04 100.00
65 INT325051 Regulation of Hand1 1 0.04 1.87 0.04 100.00
66 INT325049 Regulation of Gene_expression of Trafd1 1 0.01 0.8 0.04 100.00
67 INT245909 Positive_regulation of Transcription of Rb1 1 0.05 0.49 0.04 100.00
68 INT185288 Negative_regulation of Localization of E2F2 1 0.07 1.02 0 100.00
69 INT196429 Negative_regulation of Gene_expression of Cdkn2b 2 0.27 0.8 0 100.00
70 INT331145 Phosphorylation of Ccnb1 1 0.17 0.58 0 100.00
71 INT75502 Positive_regulation of CDKN1A 123 0.68 70.75 14.74 99.96
72 INT255238 Phosphorylation of Nsg1 1 0.12 0.47 0.07 99.96
73 INT331144 Phosphorylation of Ccnd2 1 0.01 0.57 0 99.96
74 INT65856 Positive_regulation of TP53 138 0.67 112.65 16.71 99.92
75 INT247431 Positive_regulation of Negative_regulation of RB1 2 0.45 2.58 0 99.92
76 INT197627 Localization of RB1 3 0.69 4.16 0.13 99.88
77 INT287483 Negative_regulation of Localization of IGH@ 1 0.15 1.3 0.08 99.88
78 INT124850 Gene_expression of Tpt1 42 0.77 14.51 0.79 99.86
79 INT116116 Phosphorylation of CDK4 3 0.56 2.18 1.56 99.84
80 INT252657 Positive_regulation of Phosphorylation of CDKN2A 2 0.45 3.09 0.42 99.84
81 INT185289 Phosphorylation of E2F2 3 0.11 1.39 0 99.82
82 INT129153 Phosphorylation of CDKN1B 2 0.61 1.41 0.33 99.82
83 INT93361 Gene_expression of Trp53 208 0.78 175.35 16.65 99.80
84 INT113850 Negative_regulation of Cdkn1b 4 0.42 3.45 0.6 99.80
85 INT111036 Positive_regulation of Cdkn1b 16 0.45 9 1.06 99.80
86 INT177850 Negative_regulation of MAD2L1 1 0.27 0.85 0 99.80
87 INT226416 Negative_regulation of Mcm4 1 0.13 1.29 0.17 99.76
88 INT325053 Regulation of E2f1 1 0.19 2.02 0.15 99.76
89 INT36798 Gene_expression of Mki67 178 0.77 132 8.24 99.76
90 INT75504 Gene_expression of CDK4 9 0.72 7.43 0.3 99.76
91 INT209607 Localization of IGH@ 3 0.34 2.5 0.22 99.68
92 INT245623 Negative_regulation of Cdk4 2 0.18 1.24 0 99.68
93 INT185036 Regulation of HBP1 1 0.25 0.57 0 99.68
94 INT196923 Binding of Hmga2 1 0.47 2.5 0 99.64
95 INT169931 Localization of Rb1 6 0.70 4.79 0.65 99.64
96 INT177834 Negative_regulation of BUB1 1 0.06 0.41 0 99.64
97 INT80421 Positive_regulation of IFI27 26 0.65 15.32 3.93 99.62
98 INT246286 Gene_expression of Ccnb2 1 0.01 0.47 0 99.62
99 INT281256 Positive_regulation of CCND2 1 0.20 1.42 0 99.62
100 INT235686 Gene_expression of Top2a 5 0.60 4.34 0 99.58
101 INT196419 Negative_regulation of Cdkn2b 2 0.12 0.55 0 99.56
102 INT226422 Negative_regulation of Cdk6 3 0.12 1.83 0.19 99.52
103 INT177861 Negative_regulation of CCNG1 1 0.26 0.63 0 99.52
104 INT25392 Positive_regulation of Gene_expression of Csf2 41 0.49 34.28 8.36 99.50
105 INT88414 Negative_regulation of CDK2 30 0.57 18.4 3.96 99.44
106 INT87287 Phosphorylation of CDCP1 20 0.04 5.62 2.43 99.42
107 INT185282 Localization of E2F2 3 0.47 1.92 0.25 99.42
108 INT79212 Gene_expression of Ccnd2 5 0.67 2.32 0.53 99.40
109 INT54565 Binding of SCLC1 12 0.31 20.41 0.81 99.40
110 INT233857 Positive_regulation of Binding of SCLC1 1 0.06 2.37 0.06 99.40
111 INT229004 Phosphorylation of MIA3 3 0.07 1.59 0.09 99.36
112 INT127847 Binding of RPSA 4 0.30 1.46 0.81 99.36
113 INT228997 Phosphorylation of Ccnd1 1 0.10 0.52 0 99.36
114 INT106735 Phosphorylation of CDK2 11 0.79 4.03 1.02 99.34
115 INT169945 Positive_regulation of Phosphorylation of Rb1 4 0.41 1.75 0.03 99.28
116 INT226406 Negative_regulation of Cdc2b 2 0.16 1.13 0.12 99.28
117 INT112867 Positive_regulation of Gene_expression of Ccnd1 15 0.56 13.22 1.77 99.24
118 INT25383 Gene_expression of Csf2 222 0.76 152.93 43.32 99.20
119 INT96912 Positive_regulation of Phosphorylation of Mapk8 29 0.69 18.33 8.14 99.18
120 INT135291 Positive_regulation of Positive_regulation of Mapk8 24 0.64 19.37 5.16 99.18
121 INT34977 Gene_expression of Hmga2 11 0.76 12.39 3.07 99.16
122 INT314842 Phosphorylation of Cdkn2b 1 0.71 0.61 0.03 99.16
123 INT131018 Phosphorylation of Cdkn1a 3 0.61 2.06 0.4 99.16
124 INT220423 Positive_regulation of E2f6 1 0.02 1.31 0 99.14
125 INT188065 Gene_expression of Ccnd3 3 0.45 1.48 0.27 99.12
126 INT102572 Gene_expression of Ccnd1 79 0.69 56.37 7.34 99.10
127 INT96873 Gene_expression of CYP1B1 28 0.78 11.81 1.09 99.04
128 INT226414 Negative_regulation of Ccnb1 2 0.02 2.16 0.08 99.04
129 INT196323 Localization of Cdkn2a 8 0.73 9.1 0.32 99.02
130 INT178196 Gene_expression of Vegfc 7 0.27 7.47 0.64 99.00
131 INT247423 Phosphorylation of Cdk4 1 0.32 1.14 0 99.00
132 INT247426 Negative_regulation of Phosphorylation of Cdk4 1 0.17 1.15 0 99.00
133 INT325047 Gene_expression of Hand1 1 0.07 6.42 1.06 98.96
134 INT62187 Negative_regulation of Positive_regulation of CCNDBP1 1 0.08 1.1 0.32 98.92
135 INT62188 Positive_regulation of CCNDBP1 1 0.09 1.07 0.31 98.92
136 INT201638 Positive_regulation of Cdk4 5 0.58 3.38 0.24 98.92
137 INT201656 Positive_regulation of Positive_regulation of Cdk4 2 0.06 2.34 0.15 98.92
138 INT125592 Negative_regulation of Negative_regulation of CDKN1A 2 0.42 2.07 0.41 98.86
139 INT281254 Negative_regulation of Negative_regulation of CDKN2A 1 0.08 1.44 0 98.86
140 INT281253 Negative_regulation of Negative_regulation of LAMTOR1 1 0.09 1.49 0 98.86
141 INT281250 Negative_regulation of Negative_regulation of CDKN2D 1 0.08 1.49 0 98.86
142 INT147602 Negative_regulation of CDK4 8 0.35 4.6 1.04 98.84
143 INT92141 Negative_regulation of CDKN2A 53 0.57 44.23 2.48 98.80
144 INT695 Binding of POMC 304 0.48 56.66 126.85 98.78
145 INT207289 Gene_expression of G0S2 5 0.59 2 0.07 98.76
146 INT207271 Negative_regulation of Gene_expression of G0S2 2 0.37 0.98 0.03 98.76
147 INT302260 Negative_regulation of CDK6 1 0.19 0.29 0 98.68
148 INT225182 Negative_regulation of CINP 1 0.08 0.7 0.21 98.64
149 INT90875 Negative_regulation of CCND1 31 0.42 26.22 2.66 98.64
150 INT236705 Phosphorylation of Cdk2 2 0.31 1.39 0 98.64
151 INT302266 Negative_regulation of Phosphorylation of CCNE1 1 0.02 0.29 0.03 98.60
152 INT302253 Phosphorylation of CCNE1 1 0.03 0.29 0 98.60
153 INT96913 Positive_regulation of Mapk8 179 0.69 130.44 32.2 98.56
154 INT174156 Localization of Trp53 16 0.72 13.52 1.18 98.46
155 INT89794 Positive_regulation of CDKN2A 58 0.67 50.18 5.38 98.44
156 INT205497 Binding of NOLC1 13 0.35 15.91 0.91 98.42
157 INT96915 Phosphorylation of Mapk8 73 0.81 40.69 11.44 98.40
158 INT174189 Gene_expression of E2F2 19 0.49 12.58 4.71 98.38
159 INT207288 Negative_regulation of G0S2 2 0.37 0.54 0 98.38
160 INT245901 Positive_regulation of Dlk1 1 0.25 0.48 0.04 98.34
161 INT235287 Negative_regulation of Myb 2 0.33 0.94 0 98.24
162 INT246288 Negative_regulation of Id2 1 0.01 0.45 0 98.24
163 INT182427 Binding of E2F2 7 0.23 2.78 1.49 98.16
164 INT67614 Positive_regulation of PPARA 438 0.68 293.28 63.61 98.08
165 INT103094 Binding of PPARA 308 0.47 177.26 34.75 98.08
166 INT222961 Negative_regulation of Binding of PPARA 22 0.41 10.76 2.72 98.08
167 INT109971 Positive_regulation of Tpt1 23 0.69 13.69 2.14 98.06
168 INT104330 Negative_regulation of CDKN1A 57 0.58 39.93 5.88 98.00
169 INT172970 Positive_regulation of Inca1 1 0.01 1.36 0.27 97.88
170 INT236709 Phosphorylation of Cdk6 1 0.34 0.82 0 97.84
171 INT281251 Negative_regulation of LAMTOR1 1 0.12 1.42 0 97.78
172 INT251628 Negative_regulation of CDKN2D 2 0.15 1.83 0 97.78
173 INT350896 Negative_regulation of TP53I11 1 0.41 0.67 0 97.68
174 INT297985 Positive_regulation of SCUBE3 1 0.01 0.75 0.07 97.64
175 INT153666 Gene_expression of CAV1 156 0.77 120.99 3.9 97.44
176 INT78471 Regulation of Gene_expression of CDKN2A 13 0.45 12.52 3.28 97.44
177 INT163278 Regulation of Gene_expression of CAV1 5 0.45 4.36 0.14 97.44
178 INT236692 Phosphorylation of Cdk4 2 0.35 0.82 0 97.36
179 INT47075 Positive_regulation of Ptger2 142 0.70 78.55 25.47 97.32
180 INT67039 Positive_regulation of Cpox 144 0.65 98.4 33.77 97.32
181 INT8571 Gene_expression of B3GAT1 54 0.75 36.85 15.98 97.20
182 INT147899 Binding of Lpl 6 0.30 2.07 1.82 97.20
183 INT93399 Gene_expression of Ccnd1 38 0.58 21 3.65 97.20
184 INT98554 Positive_regulation of Casp8 20 0.67 21.32 2.9 97.20
185 INT102174 Gene_expression of FASN 11 0.65 6.4 0.67 97.04
186 INT82797 Transcription of CDKN1A 11 0.69 8.01 0.32 96.96
187 INT119838 Positive_regulation of PTEN 25 0.67 21.71 2.5 96.92
188 INT236700 Phosphorylation of Ccnd1 2 0.18 1.89 0 96.88
189 INT20810 Regulation of MYCN 3 0.44 0.91 0.34 96.86
190 INT99549 Gene_expression of CDKN1B 30 0.75 17 5.15 96.80
191 INT99548 Positive_regulation of Gene_expression of CDKN1B 12 0.67 6.79 2.5 96.80
192 INT114877 Gene_expression of Cdk4 12 0.69 5.98 0.79 96.80
193 INT196430 Gene_expression of Ccnd3 5 0.14 1.92 0 96.80
194 INT23533 Gene_expression of CA2 110 0.75 30.81 19.4 96.76
195 INT467 Gene_expression of POMC 1048 0.78 332.8 394.16 96.76
196 INT75500 Negative_regulation of Gene_expression of CCND1 21 0.57 11.59 3.24 96.76
197 INT246229 Regulation of Ndrg2 1 0.03 0.49 0 96.52
198 INT196432 Binding of Ccne2 1 0.03 0.48 0 96.52
199 INT298777 Positive_regulation of Binding of Lpl 1 0.07 0.38 0.09 96.40
200 INT110023 Negative_regulation of Mapk14 127 0.59 84.27 45.42 96.16
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox