D:Retroviridae Infections

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Disease Term
Synonyms Infection Retroviridae, Infection Retrovirus, INFECTIONS RETROVIRIDAE, INFECTIONS RETROVIRUS, Retroviridae Infection, Retrovirus Infection, RETROVIRUS INFECTIONS
Documents 23
Hot Single Events 13
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Retroviridae Infections. They are ordered first by their relevance to Retroviridae Infections and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT178576 CNTN2 Positive_regulation of DPYD 1 0.05 2.18 0.76 50.00
2 INT178581 CNTN2 Positive_regulation of PTHLH 1 0.24 2.16 0.75 50.00
3 INT178577 CNTN2 Positive_regulation of IL2RA 1 0.03 2.16 0.75 50.00
4 INT178579 CNTN2 Positive_regulation of IL6 1 0.07 2.17 0.75 50.00
5 INT178575 CNTN2 Positive_regulation of PTHLH Positive_regulation of Positive_regulation of PTHLH 1 0.26 2.16 0.75 50.00
6 INT178578 Binding of PTHLH and CALCRL 1 0.01 0.68 0.27 50.00
7 INT299538 Lifr Positive_regulation of Ak5 1 0.07 0.23 0.09 15.64
8 INT299555 Lifr Positive_regulation of Gene_expression of TGFB1 1 0.03 0.23 0.09 15.64
9 INT299549 Binding of TGFB1 and Egf 1 0.02 0.32 0.32 5.00
10 INT299550 TGFB1 Negative_regulation of Glul 1 0.01 0.34 0.14 5.00
11 INT228111 Il10 Negative_regulation of Gene_expression of Ik 1 0.01 0.44 0.13 5.00
12 INT228119 Il10 Negative_regulation of H2 1 0.07 0.38 0.13 5.00
13 INT228110 Chrm2 Positive_regulation of Localization of Il10 1 0.33 0.66 0.13 5.00
14 INT299553 GOPC Positive_regulation of Stat3 1 0.02 0 0.13 5.00
15 INT228113 H2 Negative_regulation of Gene_expression of Ik 1 0.00 0.33 0.13 5.00
16 INT299547 Negative_regulation of Binding of TGFB1 and Egf 1 0.02 0.1 0.13 5.00
17 INT299551 Regulation of Binding of TGFB1 and Egf 1 0.03 0.21 0.11 5.00
18 INT228116 Tlr4 Positive_regulation of Localization of Il10 1 0.09 0.06 0.08 5.00
19 INT299539 Lif Positive_regulation of Phosphorylation of Stat3 1 0.08 0 0.08 5.00
20 INT299548 Binding of TGFB1 and Lif 1 0.02 0 0.07 5.00
21 INT299535 Binding of Egf and Lif 1 0.07 0 0.07 5.00
22 INT245369 Gpm6a Negative_regulation of Phosphorylation of Prkca 1 0.20 0.08 0.05 5.00
23 INT228120 PDLIM7 Positive_regulation of Localization of Il10 1 0.51 1.37 0 5.00
24 INT228117 Chrm2 Positive_regulation of Positive_regulation of Il10 1 0.22 0.61 0 5.00
25 INT299554 CLTCL1 Regulation of Gene_expression of Egf 1 0.00 0.16 0 5.00
26 INT228108 Il10 Negative_regulation of H2-Eb1 1 0.04 1.38 0 5.00
27 INT228118 Binding of Fyn and Vav1 1 0.11 0.21 0 5.00
28 INT228112 Gene_expression of Chrm2 Positive_regulation of Positive_regulation of Rac1 1 0.14 0.26 0 5.00
29 INT228109 Binding of Atm and Chrm2 1 0.09 0.21 0 5.00
30 INT308053 PLAT Positive_regulation of KRT20 1 0.00 0.24 0 5.00
31 INT228115 Gene_expression of Chrm2 Positive_regulation of Phosphorylation of Vav1 1 0.16 0.26 0 5.00
32 INT228114 Chrm2 Positive_regulation of Gene_expression of Il10 1 0.22 0.61 0 5.00
33 INT299552 TGFB1 Positive_regulation of Phosphorylation of Alk 1 0.00 0.12 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Retroviridae Infections. They are ordered first by their pain relevance and then by number of times they were reported in Retroviridae Infections. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT1951 Positive_regulation of Tlr4 345 0.70 176.99 62.42 99.44
2 INT15172 Positive_regulation of Itgam 45 0.67 23.54 10.3 98.34
3 INT12265 Positive_regulation of IgG 168 0.63 104.89 19.76 97.84
4 INT148402 Gene_expression of Chrm2 95 0.54 24.25 5.27 96.96
5 INT22967 Positive_regulation of RYBP 94 0.56 37.04 85.92 93.72
6 INT58145 Positive_regulation of Localization of Tnf 20 0.67 13.33 5.44 91.92
7 INT35406 Localization of Tnf 94 0.81 64.63 31.65 91.92
8 INT193042 Positive_regulation of Gene_expression of Chrm2 15 0.28 3.93 0.86 91.72
9 INT7532 Negative_regulation of Gene_expression of Ifng 33 0.59 18.56 13.14 89.52
10 INT7534 Gene_expression of Ifng 193 0.78 111.02 68.6 89.28
11 INT35086 Positive_regulation of Gene_expression of Ifng 40 0.69 22.55 18.35 89.28
12 INT15189 Localization of Npy 26 0.79 9.09 8.28 82.00
13 INT127341 Gene_expression of Gpm6a 44 0.75 3.67 13.32 80.68
14 INT10187 Gene_expression of Il2ra 91 0.78 52.67 16.66 79.44
15 INT10188 Positive_regulation of Il2ra 19 0.45 11.6 3.37 79.44
16 INT61087 Positive_regulation of Gene_expression of Il2ra 12 0.35 9.1 3.25 79.44
17 INT49749 Negative_regulation of Nr3c1 13 0.43 6.25 7.36 78.64
18 INT228084 Localization of Chrm2 8 0.36 1.54 0.11 76.96
19 INT72747 Localization of IgG 55 0.53 30.88 4.19 76.08
20 INT60694 Gene_expression of Il10 567 0.78 369.48 143.69 75.00
21 INT20374 Gene_expression of Il4 515 0.76 306.15 114.12 75.00
22 INT60691 Gene_expression of Il12a 331 0.78 208.03 75.96 75.00
23 INT11807 Gene_expression of Il2 266 0.78 112 64.97 75.00
24 INT60695 Positive_regulation of Gene_expression of Il10 154 0.70 120.28 43.07 75.00
25 INT54302 Positive_regulation of Gene_expression of Il4 126 0.68 86.18 30.75 75.00
26 INT11804 Positive_regulation of Gene_expression of Il2 70 0.70 33 21.63 75.00
27 INT60690 Positive_regulation of Gene_expression of Il12a 69 0.63 41.41 20.85 75.00
28 INT4509 Gene_expression of IgG 426 0.76 293.69 56.64 74.88
29 INT21646 Positive_regulation of Npy 40 0.70 31.31 13.57 72.56
30 INT192404 Localization of Ighm 15 0.48 5.8 0.85 70.44
31 INT28815 Gene_expression of Ighd 18 0.65 11.02 2.48 66.56
32 INT24868 Localization of Ighd 7 0.78 2.08 1.01 66.56
33 INT228101 Localization of GL7 1 0.73 0.15 0 63.68
34 INT228085 Gene_expression of GL7 1 0.65 0.58 0 63.68
35 INT228102 Localization of Il2ra 2 0.52 0.74 0.37 63.28
36 INT62031 Gene_expression of Cd19 27 0.65 10.39 0.93 62.40
37 INT163188 Localization of Cd19 8 0.62 1.27 0.09 62.40
38 INT9780 Regulation of Penk 30 0.60 6.78 17.19 61.52
39 INT89933 Negative_regulation of Tg 2 0.04 1.78 0.06 55.92
40 INT202491 Positive_regulation of Gene_expression of Cd19 3 0.42 1.29 0.09 54.36
41 INT192786 Positive_regulation of Gene_expression of Ighd 2 0.11 2.26 0.05 54.36
42 INT154706 Gene_expression of Tg 9 0.38 4.95 0.64 51.92
43 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 50.00
44 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 50.00
45 INT12082 Localization of IL6 365 0.81 241.78 105.78 50.00
46 INT9210 Regulation of IL6 166 0.62 125.61 49.95 50.00
47 INT50230 Positive_regulation of Localization of IL6 105 0.70 69.21 29.52 50.00
48 INT12084 Regulation of Localization of IL6 36 0.61 20.32 12.34 50.00
49 INT24816 Binding of CD40LG 68 0.47 45.48 11.56 50.00
50 INT5788 Gene_expression of IL2RA 60 0.75 40.67 9.98 50.00
51 INT17701 Gene_expression of PTHLH 103 0.78 64.23 8.85 50.00
52 INT11747 Positive_regulation of IL2RA 22 0.67 16.55 6.95 50.00
53 INT69395 Gene_expression of CNTN2 28 0.68 13.29 4.37 50.00
54 INT62360 Positive_regulation of PTHLH 31 0.70 28.23 3.46 50.00
55 INT94690 Gene_expression of DPYD 12 0.75 4.6 1.07 50.00
56 INT114824 Binding of PTHLH 12 0.42 9.5 0.9 50.00
57 INT178587 Positive_regulation of DPYD 4 0.50 4.7 0.74 50.00
58 INT178590 Regulation of CNTN2 7 0.24 2.91 0.68 50.00
59 INT69392 Positive_regulation of Gene_expression of CNTN2 3 0.44 2.43 0.58 50.00
60 INT178589 Localization of IL2RA 3 0.68 1.99 0.45 50.00
61 INT178591 Binding of CNTN2 4 0.23 1.56 0.44 50.00
62 INT178586 Localization of DPYD 1 0.36 0.76 0.42 50.00
63 INT178585 Regulation of Binding of CNTN2 1 0.21 0.71 0.3 50.00
64 INT178592 Binding of ACP1 1 0.14 1.93 0.25 50.00
65 INT178584 Regulation of Gene_expression of CNTN2 1 0.21 1.39 0.24 50.00
66 INT173716 Positive_regulation of Cd44 7 0.44 4.65 1.45 49.92
67 INT299521 Regulation of Cd44 1 0.12 0.36 0 49.92
68 INT14031 Gene_expression of Npy 107 0.78 36.48 35.4 44.92
69 INT21794 Positive_regulation of Gene_expression of Npy 20 0.70 8.44 9.3 44.92
70 INT185245 Gene_expression of Skull21 7 0.27 1.47 0.4 40.08
71 INT173974 Positive_regulation of Localization of Il10 25 0.68 16.81 5.87 36.32
72 INT90792 Localization of Il10 144 0.80 87.88 30.03 35.96
73 INT228093 Regulation of Gene_expression of Chrm2 1 0.22 0.4 0.19 33.56
74 INT59891 Positive_regulation of GSTK1 46 0.67 17.66 5.33 30.80
75 INT79927 Localization of GSTK1 5 0.40 1.29 1.21 30.80
76 INT299543 Positive_regulation of Localization of GSTK1 1 0.04 0.31 0 30.80
77 INT85640 Gene_expression of Tg(CAG-EGFP)D4Nagy 1138 0.72 311.58 119.18 24.40
78 INT111401 Positive_regulation of Gene_expression of Tg(CAG-EGFP)D4Nagy 134 0.61 34.87 20.15 24.40
79 INT85639 Positive_regulation of Tg(CAG-EGFP)D4Nagy 95 0.43 24.83 15.69 24.40
80 INT8243 Positive_regulation of Il6 451 0.70 358.24 119.28 16.48
81 INT63975 Positive_regulation of Il10 175 0.68 134.13 54.69 16.48
82 INT11803 Positive_regulation of Il2 62 0.70 31.44 18.93 16.48
83 INT14733 Positive_regulation of Gene_expression of TGFB1 71 0.69 49.89 22.2 15.64
84 INT149594 Positive_regulation of Gene_expression of Lif 2 0.47 0.89 1 15.64
85 INT299517 Positive_regulation of Gene_expression of Il6st 1 0.06 0.23 0.09 15.64
86 INT299520 Positive_regulation of Gene_expression of Lifr 1 0.18 0.23 0.09 15.64
87 INT299522 Positive_regulation of Gene_expression of Ak5 1 0.18 0.23 0.09 15.64
88 INT14740 Gene_expression of TGFB1 272 0.78 168.48 60.18 15.00
89 INT32208 Gene_expression of Lif 23 0.74 6.23 3.7 15.00
90 INT89986 Gene_expression of Il6st 5 0.56 2.35 3.15 15.00
91 INT148637 Gene_expression of Lifr 5 0.75 0.92 0.18 15.00
92 INT299518 Gene_expression of Ak5 1 0.24 0.23 0.09 15.00
93 INT124954 Gene_expression of Egfr 26 0.75 15.08 3.12 8.84
94 INT9659 Gene_expression of Il6 991 0.78 715.11 265.57 5.00
95 INT5842 Gene_expression of Gfap 372 0.78 153.71 127.71 5.00
96 INT1878 Binding of HLA-B 440 0.48 321.16 127.36 5.00
97 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 5.00
98 INT5843 Positive_regulation of Gfap 184 0.70 108.2 70.21 5.00
99 INT11937 Localization of Il6 228 0.81 139.83 64.39 5.00
100 INT9657 Positive_regulation of Gene_expression of Il6 237 0.70 180.45 63.6 5.00
101 INT55671 Gene_expression of Ik 151 0.27 80.1 48.49 5.00
102 INT6864 Positive_regulation of Gene_expression of Gfap 110 0.70 59.01 47.07 5.00
103 INT16364 Gene_expression of HLA-DRA 234 0.78 118.81 45.01 5.00
104 INT4216 Gene_expression of CD40LG 328 0.78 256.02 44.23 5.00
105 INT57442 Phosphorylation of Prkca 98 0.70 31.58 41.04 5.00
106 INT49214 Gene_expression of Cd4 269 0.78 154.22 34.05 5.00
107 INT10248 Gene_expression of KRT20 436 0.78 231.96 32.88 5.00
108 INT15610 Localization of GOPC 223 0.65 68.26 28.7 5.00
109 INT9155 Gene_expression of Glul 60 0.77 17.97 23.95 5.00
110 INT49553 Regulation of Gene_expression of Gfap 42 0.62 17.04 23.65 5.00
111 INT14731 Positive_regulation of TGFB1 78 0.67 52.57 22.23 5.00
112 INT5328 Positive_regulation of CD4 191 0.69 133.43 21.31 5.00
113 INT66923 Localization of Ik 54 0.07 19.78 20.84 5.00
114 INT86751 Negative_regulation of Il10 62 0.59 40.1 20.51 5.00
115 INT105021 Binding of GOPC 187 0.40 60.39 20.38 5.00
116 INT88949 Positive_regulation of Il12a 79 0.60 47.68 19.98 5.00
117 INT48663 Negative_regulation of Gene_expression of Gfap 45 0.59 18.34 19.84 5.00
118 INT12081 Localization of TGFB1 64 0.81 35.4 17.47 5.00
119 INT22900 Positive_regulation of Cd4 126 0.67 82.77 16.43 5.00
120 INT3796 Gene_expression of Ighm 130 0.77 69.61 13.78 5.00
121 INT20381 Localization of Il2 71 0.77 34.23 13.03 5.00
122 INT13823 Gene_expression of Egf 97 0.78 39.99 12.99 5.00
123 INT107875 Phosphorylation of Stat3 49 0.80 13.18 12.66 5.00
124 INT87239 Localization of Il12a 51 0.75 31.95 12.05 5.00
125 INT71768 Regulation of Gene_expression of Il10 27 0.62 19.17 10.4 5.00
126 INT71769 Negative_regulation of Gene_expression of Il10 40 0.57 22.53 10.37 5.00
127 INT20371 Gene_expression of Cd8a 125 0.60 67.59 8.97 5.00
128 INT22771 Positive_regulation of Egf 44 0.70 16.45 8.64 5.00
129 INT4991 Positive_regulation of Vim 74 0.69 69.84 8.33 5.00
130 INT36798 Gene_expression of Mki67 178 0.77 132 8.24 5.00
131 INT131359 Positive_regulation of Gene_expression of Cd4 40 0.58 22.43 7.53 5.00
132 INT18909 Positive_regulation of Cd8a 92 0.60 56.55 7.35 5.00
133 INT6861 Negative_regulation of Gfap 32 0.58 13.71 7.22 5.00
134 INT8793 Gene_expression of H2 58 0.75 26.36 7.07 5.00
135 INT1926 Positive_regulation of PLAT 54 0.66 31.42 6.49 5.00
136 INT3795 Positive_regulation of Ighm 46 0.68 22.43 6.47 5.00
137 INT25385 Positive_regulation of Localization of Il2 17 0.45 9.53 6.45 5.00
138 INT13822 Localization of Egf 30 0.81 13.79 6.4 5.00
139 INT129918 Positive_regulation of Phosphorylation of Stat3 17 0.63 5.42 6.28 5.00
140 INT39416 Gene_expression of Cd79a 81 0.64 45.17 6.08 5.00
141 INT17551 Positive_regulation of Gene_expression of HLA-DRA 31 0.70 15.39 6 5.00
142 INT186063 Phosphorylation of SOAT1 29 0.28 11.77 5.34 5.00
143 INT18681 Gene_expression of Thy1 80 0.71 38.8 5.23 5.00
144 INT89104 Binding of TGFB1 29 0.44 13.67 5.12 5.00
145 INT21901 Negative_regulation of Egf 25 0.58 10.46 4.99 5.00
146 INT178754 Positive_regulation of Localization of GOPC 32 0.43 10.1 4.73 5.00
147 INT209566 Negative_regulation of Localization of Ik 7 0.01 3.83 4.71 5.00
148 INT35765 Gene_expression of TXNRD1 47 0.56 9.16 4.43 5.00
149 INT137178 Gene_expression of TLR3 46 0.72 24.97 4.33 5.00
150 INT57645 Gene_expression of GSTK1 54 0.62 21.05 4.2 5.00
151 INT65926 Positive_regulation of Gene_expression of Egf 26 0.70 12.91 4.18 5.00
152 INT97392 Gene_expression of Stat3 27 0.65 14.21 4.06 5.00
153 INT81213 Binding of Gpm6a 6 0.35 0.72 3.87 5.00
154 INT49006 Gene_expression of Neu3 13 0.08 1.22 3.63 5.00
155 INT50648 Negative_regulation of Gene_expression of Glul 9 0.58 2.7 3.53 5.00
156 INT51848 Transcription of TGFB1 17 0.69 9.57 3.53 5.00
157 INT194848 Negative_regulation of Localization of Il10 11 0.36 8.29 3.38 5.00
158 INT9130 Negative_regulation of TGFB1 16 0.41 12.21 2.92 5.00
159 INT239596 Positive_regulation of POMT1 29 0.40 9.92 2.8 5.00
160 INT57957 Localization of TXNRD1 14 0.64 4.01 2.7 5.00
161 INT77636 Phosphorylation of Egf 11 0.61 1.69 2.56 5.00
162 INT191017 Localization of Cd79a 28 0.56 13.94 2.55 5.00
163 INT90791 Regulation of Localization of Il10 6 0.44 2.94 2.5 5.00
164 INT55123 Binding of Ceacam1 4 0.30 4.86 2.44 5.00
165 INT8466 Binding of Plp1 5 0.48 5.07 2.29 5.00
166 INT24740 Positive_regulation of Cd79a 36 0.48 14.71 2.17 5.00
167 INT3797 Positive_regulation of Gene_expression of Ighm 16 0.47 9.4 2.01 5.00
168 INT44027 Positive_regulation of Lif 7 0.40 2.76 1.9 5.00
169 INT26850 Negative_regulation of H2 13 0.32 9.4 1.82 5.00
170 INT223746 Binding of Il10 12 0.36 9.49 1.73 5.00
171 INT94827 Gene_expression of HBS1L 24 0.67 26.11 1.61 5.00
172 INT161371 Gene_expression of Glul 7 0.61 2.44 1.58 5.00
173 INT110992 Positive_regulation of Positive_regulation of TGFB1 4 0.50 3.01 1.51 5.00
174 INT63328 Binding of Fgf1 10 0.37 1.5 1.4 5.00
175 INT103755 Positive_regulation of Negative_regulation of Il10 3 0.49 2.64 1.4 5.00
176 INT72916 Binding of Npy 2 0.41 1.5 1.37 5.00
177 INT173892 Phosphorylation of TGFB1 8 0.79 2.63 1.3 5.00
178 INT60542 Positive_regulation of Gene_expression of GSTK1 11 0.39 6.21 1.13 5.00
179 INT22770 Regulation of Gene_expression of Egf 5 0.44 2.56 1.12 5.00
180 INT186807 Positive_regulation of Gene_expression of TLR3 8 0.53 7.19 1.08 5.00
181 INT61643 Gene_expression of ACVRL1 9 0.51 9.04 1.03 5.00
182 INT184051 Binding of Ik 3 0.01 0.25 1.01 5.00
183 INT264171 Positive_regulation of Positive_regulation of CD4 5 0.49 4.74 0.94 5.00
184 INT228088 Localization of Ceacam1 6 0.54 4.64 0.85 5.00
185 INT180534 Gene_expression of SARS 40 0.59 35.47 0.81 5.00
186 INT186804 Binding of TLR3 14 0.45 8.41 0.79 5.00
187 INT178175 Positive_regulation of Gene_expression of Cd8a 17 0.43 13.05 0.78 5.00
188 INT228105 Negative_regulation of Gene_expression of Chrm2 5 0.25 3.17 0.75 5.00
189 INT227949 Negative_regulation of Chrm2 8 0.25 4.23 0.73 5.00
190 INT15264 Gene_expression of TRAFD1 5 0.23 3.56 0.71 5.00
191 INT200750 Gene_expression of Rho 19 0.65 6.52 0.69 5.00
192 INT28118 Binding of Atm 13 0.38 12.24 0.68 5.00
193 INT96840 Negative_regulation of H2-K1 7 0.33 1.35 0.67 5.00
194 INT193037 Regulation of Chrm2 7 0.19 8.82 0.64 5.00
195 INT78495 Negative_regulation of Art2a-ps 2 0.23 1.03 0.59 5.00
196 INT78494 Negative_regulation of Oas1b 2 0.22 1.02 0.59 5.00
197 INT173891 Positive_regulation of Phosphorylation of TGFB1 4 0.49 2 0.59 5.00
198 INT228103 Positive_regulation of Rac1 25 0.67 18.92 0.57 5.00
199 INT189289 Negative_regulation of Gene_expression of H2 4 0.18 1.27 0.56 5.00
200 INT194335 Gene_expression of Nefl 15 0.51 5.64 0.51 5.00
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