D:Rheumatic Heart Disease

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Disease Term
Synonyms Bouillaud Disease, Bouillaud S Disease, Bouillauds Disease, Disease Bouillaud, Disease Bouillaud S, Disease Rheumatic Heart, Diseases Rheumatic Heart, Heart Disease Rheumatic, HEART DISEASES RHEUMATIC, Rheumatic Heart Diseases
Documents 100
Hot Single Events 26
Hot Interactions 3

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Rheumatic Heart Disease. They are ordered first by their relevance to Rheumatic Heart Disease and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT68480 Negative_regulation of Gnrh1 Regulation of Lhb 1 0.00 0.67 0.15 99.84
2 INT68479 Gnrh1 Regulation of Lhb 1 0.00 1.58 0.25 98.80
3 INT68482 Cga Regulation of Gh 1 0.00 1.89 0.31 87.32
4 INT348322 Il6 Positive_regulation of Localization of Crp 1 0.06 3.51 0.51 5.00
5 INT348323 Binding of Crp and Il6 1 0.05 0.06 0.03 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Rheumatic Heart Disease. They are ordered first by their pain relevance and then by number of times they were reported in Rheumatic Heart Disease. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT2105 Negative_regulation of Rhd 10 0.41 4.9 3.4 100.00
2 INT2103 Localization of Rhd 35 0.77 3.16 23.5 100.00
3 INT61076 Gene_expression of RHD 9 0.65 3.52 1.39 100.00
4 INT61140 Regulation of Negative_regulation of Rf 1 0.05 1.45 0.1 99.96
5 INT9837 Negative_regulation of Rf 12 0.11 8.41 4.55 99.96
6 INT29424 Negative_regulation of Positive_regulation of Lhb 21 0.56 4.58 4.03 99.84
7 INT9785 Negative_regulation of Positive_regulation of Gnrh1 18 0.43 1.88 7.35 99.84
8 INT28951 Negative_regulation of IGF1 133 0.59 75.77 18.9 99.60
9 INT5128 Positive_regulation of Lhb 232 0.69 44.23 71.26 98.80
10 INT2123 Positive_regulation of Gnrh1 209 0.70 24.2 68.97 98.72
11 INT2093 Gene_expression of GAST 50 0.78 32.32 7.98 97.96
12 INT1530 Regulation of Gh 382 0.61 115.96 112.47 95.76
13 INT4137 Positive_regulation of C3 73 0.69 48.57 12.63 93.80
14 INT1123 Positive_regulation of CD79A 74 0.70 51.96 7.14 93.80
15 INT11109 Positive_regulation of Serpina1a 5 0.68 4.97 1.12 93.68
16 INT71418 Binding of CES1 42 0.40 29.78 5.01 92.60
17 INT17401 Gene_expression of IGF1 475 0.78 232.18 62.07 89.56
18 INT28952 Negative_regulation of Gene_expression of IGF1 75 0.58 41.11 12.32 89.56
19 INT9408 Positive_regulation of Crp 296 0.69 242.27 57.35 88.80
20 INT7224 Positive_regulation of Gene_expression of Lhb 18 0.45 10.22 3.4 87.92
21 INT2261 Gene_expression of Lhb 121 0.77 42.78 26.04 87.92
22 INT3448 Positive_regulation of Gh 521 0.69 180.03 161.18 87.32
23 INT5126 Positive_regulation of Positive_regulation of Lhb 16 0.48 2.12 5.23 86.52
24 INT23367 Positive_regulation of Positive_regulation of Gnrh1 9 0.50 0.97 2.97 84.68
25 INT13556 Gene_expression of CD4 367 0.78 230.82 41.74 82.32
26 INT56985 Gene_expression of MEFV 56 0.71 46.71 9.47 81.12
27 INT636 Binding of MRAP 54 0.48 40.36 18.77 75.00
28 INT16130 Binding of IGF1 67 0.48 27.43 2.95 70.72
29 INT9682 Positive_regulation of IGF1 238 0.70 120.03 26.36 45.92
30 INT28950 Positive_regulation of Gene_expression of IGF1 99 0.69 46.9 16.47 45.92
31 INT158354 Negative_regulation of Binding of Il6 2 0.20 2.21 0.71 42.80
32 INT51474 Binding of Il6 55 0.48 44.99 20.52 36.08
33 INT9973 Binding of MMVP1 14 0.48 22.66 1.79 28.24
34 INT15516 Gene_expression of Crp 711 0.77 615.33 173.09 17.40
35 INT47939 Gene_expression of Selp 171 0.76 87.54 39.03 17.40
36 INT76123 Gene_expression of Lep 193 0.78 94.17 22.76 17.40
37 INT117500 Gene_expression of Adipoq 90 0.74 67.79 16.58 17.40
38 INT15918 Gene_expression of Serpine1 60 0.62 41.73 7.72 17.40
39 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 5.00
40 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 5.00
41 INT16868 Gene_expression of Il6 807 0.78 499.48 256.57 5.00
42 INT17612 Gene_expression of CRP 676 0.78 580.61 119.03 5.00
43 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74 5.00
44 INT2774 Binding of Crp 241 0.48 195.89 44.39 5.00
45 INT17331 Positive_regulation of JUN 132 0.69 60.4 27.03 5.00
46 INT100861 Binding of CRP 179 0.48 175.2 26.45 5.00
47 INT17739 Gene_expression of S100B 226 0.78 132.7 26.4 5.00
48 INT11659 Gene_expression of COL2A1 164 0.78 78.49 22.58 5.00
49 INT23257 Regulation of CRP 127 0.62 100.05 21.87 5.00
50 INT38056 Localization of Crp 71 0.78 53.14 17.03 5.00
51 INT3793 Regulation of CEBPZ 59 0.61 20.91 15.83 5.00
52 INT39507 Positive_regulation of TXNRD1 37 0.68 12.47 14.25 5.00
53 INT18012 Gene_expression of EPO 169 0.78 108.36 13.75 5.00
54 INT15921 Positive_regulation of Serpine1 85 0.68 81.24 13.4 5.00
55 INT10870 Regulation of IgG 67 0.59 43.27 12.74 5.00
56 INT50933 Transcription of Il6 38 0.72 24.31 11.58 5.00
57 INT15449 Positive_regulation of Plat 32 0.69 12.76 9.71 5.00
58 INT11729 Regulation of IGF1 71 0.61 44.58 9.71 5.00
59 INT130731 Protein_catabolism of COL2A1 47 0.96 21.86 9.28 5.00
60 INT64346 Positive_regulation of S100B 95 0.70 63.11 9.17 5.00
61 INT34777 Localization of IGF1 82 0.80 42.68 8.62 5.00
62 INT7125 Gene_expression of PLA2G2A 47 0.78 42.12 7.83 5.00
63 INT153300 Negative_regulation of Gene_expression of CRP 48 0.58 39.97 7.58 5.00
64 INT9951 Gene_expression of ANGPTL5 45 0.53 37.2 6.44 5.00
65 INT21103 Gene_expression of Dbp 48 0.61 22.6 5.59 5.00
66 INT20552 Negative_regulation of Gene_expression of COL2A1 29 0.56 11.92 4.81 5.00
67 INT35765 Gene_expression of TXNRD1 47 0.56 9.16 4.43 5.00
68 INT217742 Positive_regulation of Gene_expression of COL2A1 20 0.67 9.76 4.23 5.00
69 INT61680 Positive_regulation of PVR 23 0.60 23.27 3.86 5.00
70 INT14837 Gene_expression of PLA2G1B 12 0.60 10.69 3.58 5.00
71 INT131187 Regulation of Gene_expression of IGF1 18 0.62 11.18 3.05 5.00
72 INT131929 Positive_regulation of Gene_expression of S100B 25 0.67 12.61 2.83 5.00
73 INT216365 Gene_expression of CASP2 8 0.65 3.27 2.75 5.00
74 INT82966 Transcription of Crp 14 0.70 9.91 2.61 5.00
75 INT2405 Negative_regulation of SGCA 15 0.57 6.04 2.45 5.00
76 INT183668 Binding of SGCA 15 0.36 9.86 2.42 5.00
77 INT193582 Gene_expression of PVR 21 0.58 14 2.39 5.00
78 INT3798 Negative_regulation of GNS 5 0.26 3.18 2.21 5.00
79 INT47804 Negative_regulation of Gspt1 3 0.29 1.94 2.04 5.00
80 INT192295 Protein_catabolism of MMP7 10 0.86 2.68 1.86 5.00
81 INT25544 Positive_regulation of Hapln1 3 0.12 8.58 1.44 5.00
82 INT70615 Binding of TXNRD1 25 0.36 12.15 1.27 5.00
83 INT35148 Regulation of ANGPTL5 12 0.28 6.92 1.14 5.00
84 INT217744 Positive_regulation of GNS 4 0.24 1.39 1 5.00
85 INT71614 Localization of GNS 3 0.78 1.49 0.84 5.00
86 INT171772 Binding of CPB1 13 0.32 9.92 0.75 5.00
87 INT165813 Gene_expression of CES1 31 0.76 6.08 0.66 5.00
88 INT217743 Gene_expression of GNS 3 0.32 1.37 0.65 5.00
89 INT47805 Positive_regulation of Gspt1 5 0.11 1.02 0.47 5.00
90 INT190309 Localization of SGCA 3 0.20 1.94 0.45 5.00
91 INT217745 Positive_regulation of Protein_catabolism of GNS 1 0.01 0.34 0.33 5.00
92 INT217741 Positive_regulation of Localization of GNS 1 0.01 0.34 0.33 5.00
93 INT217740 Protein_catabolism of GNS 1 0.01 0.34 0.32 5.00
94 INT192302 Negative_regulation of Protein_catabolism of MMP7 2 0.01 0.21 0.26 5.00
95 INT303530 Gene_expression of Gspt1 2 0.07 1.23 0.1 5.00
96 INT198611 Binding of PFKFB4 2 0.04 0.37 0.05 5.00
97 INT183747 Positive_regulation of NNT 1 0.44 0.63 0 5.00
98 INT347959 Negative_regulation of Localization of SGCA 1 0.11 0 0 5.00
99 INT239357 Localization of Iars 1 0.06 0.41 0 5.00
100 INT183746 Positive_regulation of Positive_regulation of NNT 1 0.29 0.63 0 5.00
101 INT347958 Regulation of PFKFB4 1 0.03 0.17 0 5.00
102 INT350311 Positive_regulation of Gene_expression of Gspt1 1 0.05 1.09 0 5.00
103 INT347960 Localization of PFKFB4 1 0.08 0 0 5.00
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