D:Rheumatic Nodule

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Disease Term
Synonyms Aschoff Bodies, Bodies Aschoff, Nodule Rheumatic, Nodules Rheumatic, Rheumatic Nodules
Documents 4
Hot Single Events 0
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Rheumatic Nodule. They are ordered first by their relevance to Rheumatic Nodule and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT122163 Binding of TNF and TNFRSF1B 6 0.44 6.06 2.41 5.00
2 INT271875 IL1RN Negative_regulation of Binding of IL1B 1 0.01 1.3 1.01 5.00
3 INT271874 IL10 Negative_regulation of TNF 1 0.07 0.78 0.5 5.00
4 INT271872 IL10 Regulation of IK 1 0.00 0.81 0.47 5.00
5 INT271873 IL10 Regulation of Gene_expression of IK 1 0.00 0.81 0.47 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Rheumatic Nodule. They are ordered first by their pain relevance and then by number of times they were reported in Rheumatic Nodule. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT56651 Binding of HLA-DRB1 58 0.48 52.25 13.68 67.36
2 INT94082 Regulation of Gene_expression of IK 19 0.23 10.03 7.93 64.28
3 INT52264 Gene_expression of IK 180 0.77 90.87 51.87 63.84
4 INT11699 Binding of HLA-E 85 0.47 52.51 13.41 55.92
5 INT85417 Positive_regulation of Gene_expression of IK 17 0.09 9.38 5.73 28.60
6 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 14.04
7 INT6852 Localization of TNF 883 0.81 705.95 270.84 7.44
8 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 5.00
9 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 5.00
10 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97 5.00
11 INT6481 Binding of TNF 624 0.48 510.2 214.82 5.00
12 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210 5.00
13 INT9660 Regulation of TNF 363 0.62 312.94 139.99 5.00
14 INT11051 Positive_regulation of Gene_expression of IL6 415 0.69 319.21 109.3 5.00
15 INT60526 Gene_expression of IL10 449 0.78 292.71 107.84 5.00
16 INT48901 Negative_regulation of IL6 186 0.57 136.33 57.87 5.00
17 INT48232 Gene_expression of MMP1 245 0.78 96.31 57.72 5.00
18 INT9234 Negative_regulation of Gene_expression of IL6 171 0.59 101.61 53.15 5.00
19 INT9210 Regulation of IL6 166 0.62 125.61 49.95 5.00
20 INT13354 Transcription of TNF 108 0.72 85.81 42.32 5.00
21 INT29496 Gene_expression of MMP3 136 0.75 49.49 41.78 5.00
22 INT6484 Binding of IL1B 122 0.47 75.84 35.07 5.00
23 INT132161 Gene_expression of MTX1 48 0.58 26.55 32.32 5.00
24 INT70048 Positive_regulation of Gene_expression of IL10 90 0.55 71.34 25.66 5.00
25 INT9237 Regulation of Gene_expression of IL1B 49 0.62 30.69 20.34 5.00
26 INT6478 Negative_regulation of Binding of TNF 36 0.58 30.42 13.31 5.00
27 INT52625 Regulation of IL1RN 30 0.61 19.12 11.31 5.00
28 INT23402 Binding of HLA-DOA 74 0.48 52.01 10.89 5.00
29 INT54473 Binding of ABCB1 30 0.48 8.65 10.38 5.00
30 INT103554 Positive_regulation of MTX1 19 0.45 11.23 10 5.00
31 INT73558 Regulation of IK 23 0.23 12.02 8.73 5.00
32 INT122165 Binding of TNFRSF1B 8 0.28 7.46 4.87 5.00
33 INT211133 Negative_regulation of MTX1 8 0.19 3.86 4.87 5.00
34 INT109448 Negative_regulation of MTHFR 8 0.58 7.62 3.11 5.00
35 INT99911 Localization of MTX1 5 0.45 3.81 3.07 5.00
36 INT6479 Negative_regulation of Binding of IL1B 10 0.43 5.1 2.78 5.00
37 INT124063 Gene_expression of MTHFR 9 0.65 6.22 2.67 5.00
38 INT213681 Gene_expression of TYMS 9 0.33 8.96 2.45 5.00
39 INT76226 Binding of SPANXB1 6 0.24 1.16 2.23 5.00
40 INT79606 Negative_regulation of NAT2 5 0.59 0.31 2.1 5.00
41 INT174240 Negative_regulation of TYMS 12 0.57 6.35 1.82 5.00
42 INT271886 Transcription of TNFRSF1B 1 0.51 1.76 1.23 5.00
43 INT191311 Binding of Das 3 0.03 2.56 0.99 5.00
44 INT165401 Phosphorylation of IL1RN 2 0.09 1.51 0.91 5.00
45 INT230087 Binding of TOR1A 6 0.35 2.84 0.68 5.00
46 INT253325 Positive_regulation of Negative_regulation of MTHFR 2 0.44 1.22 0.49 5.00
47 INT113219 Binding of TNFRSF25 12 0.35 9.77 0.46 5.00
48 INT201091 Regulation of HLA-DOA 5 0.20 3.6 0.44 5.00
49 INT271883 Positive_regulation of Localization of ADAMTS5 1 0.02 0.33 0.39 5.00
50 INT271887 Localization of ADAMTS5 1 0.02 0.32 0.38 5.00
51 INT271882 Protein_catabolism of TXN 1 0.09 0.17 0.31 5.00
52 INT258183 Negative_regulation of GCSH 1 0.02 2.33 0.05 5.00
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