D:Rheumatoid Arthritis

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Disease Term
Synonyms ACUTE CHRONIC PAIN RHEUMATOID ARTHRITIS, Arthritis Rheumatoid, BAKER S CYST, JUVENILE RHEUMATOID ARTHRITIS, Ra, Rheumatoid Arthritis Chronic Bronchitis, Rheumatoid Nodule, RHEUMATOID NODULES
Documents 10337
Hot Single Events 200
Hot Interactions 200

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Rheumatoid Arthritis. They are ordered first by their relevance to Rheumatoid Arthritis and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT176368 IL18 Positive_regulation of Gene_expression of IFNA1 1 0.16 2.53 1.35 100.00
2 INT182159 Binding of HGF and DCPS 1 0.01 2.5 1.17 100.00
3 INT207437 Binding of PLA2G7 and ERAL1 1 0.14 3.64 1.11 100.00
4 INT207439 Binding of HCRT and ERAL1 1 0.00 3.06 0.87 100.00
5 INT83427 Binding of IGHG3 and FRTS 3 0.03 1.92 1.12 100.00
6 INT238914 Positive_regulation of CNR1 Positive_regulation of Phosphorylation of MAPK1 1 0.19 3.22 2.35 100.00
7 INT187171 Binding of Tnfrsf1b and Gtf3a 1 0.03 2.15 0.72 100.00
8 INT182156 Binding of HGF and IL3RA 1 0.03 1.31 0.62 100.00
9 INT239064 Binding of Mbl1 and IgG 1 0.03 2.59 0.78 100.00
10 INT176365 IL12A Positive_regulation of Gene_expression of IFNA1 1 0.13 1.35 0.6 100.00
11 INT285569 TNF Negative_regulation of Gene_expression of Il6 1 0.03 2.83 1.46 100.00
12 INT222486 Crem Positive_regulation of Gh1 1 0.00 1.13 0 100.00
13 INT174451 Trav6-3 Regulation of Transcription of Cxcr3 1 0.06 1.86 1 100.00
14 INT346204 Binding of S100A10 and TPPP 1 0.02 1.62 0.97 100.00
15 INT187174 RPS3AP9 Negative_regulation of MMP2 1 0.00 0.9 1.22 100.00
16 INT187172 RPS3AP9 Negative_regulation of MMP9 1 0.00 0.89 1.2 100.00
17 INT264327 IL-17 Positive_regulation of Gene_expression of Tnfsf11 1 0.07 3.19 1.33 100.00
18 INT278693 ERAL1 Positive_regulation of CD4 1 0.05 1.1 0.31 100.00
19 INT278692 ERAL1 Positive_regulation of Positive_regulation of CD4 1 0.05 1.1 0.31 100.00
20 INT206849 ESR1 Regulation of Gene_expression of ALDH1A1 1 0.11 2.26 0.04 100.00
21 INT182158 Binding of IL3RA and DCPS 1 0.06 0.77 0.39 100.00
22 INT333991 Binding of FLNA and SELL 1 0.00 1.69 0.55 100.00
23 INT83422 Binding of FANCB and IGHG3 3 0.12 5.09 1.22 100.00
24 INT188531 Binding of TNF and PDXK 1 0.03 1.99 0.78 100.00
25 INT238916 CNR1 Positive_regulation of Phosphorylation of MAPK1 1 0.19 1.61 1.17 100.00
26 INT206852 ESR1 Regulation of Gene_expression of CRABP2 1 0.08 1.52 0.04 100.00
27 INT285205 Binding of VEGFA and SLEB1 1 0.05 5.12 0.38 100.00
28 INT224726 Negative_regulation of Binding of Fgf2 and Cia1 1 0.01 0.92 0.62 100.00
29 INT182931 VDR Positive_regulation of Gene_expression of CDKN1A 1 0.48 0.86 0 100.00
30 INT224733 Negative_regulation of Binding of VEGFA and Cia1 1 0.01 0.91 0.61 100.00
31 INT224727 Binding of Fgf2 and Cia1 1 0.01 0.91 0.61 100.00
32 INT224731 Binding of VEGFA and Cia1 1 0.01 0.91 0.61 100.00
33 INT192106 Regulation of Binding of Rara and Retsat 1 0.00 0.83 0.13 100.00
34 INT192102 Regulation of Binding of Rxrg and Retsat 1 0.01 0.83 0.13 100.00
35 INT192101 Binding of Rxrg and Regulation of Retsat 1 0.00 0.83 0.13 100.00
36 INT192103 Binding of Rxrg and Retsat 1 0.01 0.83 0.13 100.00
37 INT192105 Binding of Rara and Retsat 1 0.00 0.83 0.13 100.00
38 INT192104 Binding of Rara and Rxrg 1 0.00 0.82 0.1 100.00
39 INT174453 Smcp Positive_regulation of Cxcr3 1 0.17 1.29 0.64 100.00
40 INT258339 Binding of Aicda and Scara3 1 0.05 0.67 0.32 100.00
41 INT222574 Crem Positive_regulation of Pou1f1 1 0.00 0.57 0 100.00
42 INT222672 Crem Positive_regulation of Crem Positive_regulation of Gh1 1 0.00 0.56 0 100.00
43 INT176479 IL17A Positive_regulation of Gene_expression of TIMP1 1 0.02 1.33 0.74 100.00
44 INT346226 Binding of TPPP and Braf 1 0.06 0.6 0.33 100.00
45 INT239501 Binding of Adora2a and Mtx1 1 0.24 0.95 0.64 100.00
46 INT329956 Binding of IL2 and IL23R 1 0.33 4.58 1.21 100.00
47 INT335259 Binding of GSTM1 and RA1 1 0.11 0.78 0.13 100.00
48 INT346150 Binding of ADM and FN1 1 0.10 0.93 0.39 100.00
49 INT346135 Positive_regulation of Binding of ADM and FN1 1 0.13 0.93 0.39 100.00
50 INT346148 Binding of ADM and VTN 1 0.15 0.93 0.39 100.00
51 INT346142 Positive_regulation of Binding of ADM and VTN 1 0.20 0.93 0.39 100.00
52 INT346140 Positive_regulation of Binding of ADM and MMRN1 1 0.04 0.93 0.39 100.00
53 INT346139 Binding of ADM and MMRN1 1 0.03 0.93 0.39 100.00
54 INT302838 TNF Positive_regulation of Sox18 1 0.00 0.71 0.5 100.00
55 INT323702 HGF Regulation of Gene_expression of CRP 1 0.01 0.81 0.43 100.00
56 INT181899 TNF Regulation of ANGPT1 1 0.03 1.22 0.33 100.00
57 INT181893 TNF Regulation of ANGPT2 1 0.04 1.22 0.33 100.00
58 INT181896 TNF Regulation of TEK 1 0.03 1.21 0.33 100.00
59 INT302832 Tnfsf10 Positive_regulation of Akt1 1 0.04 1.63 0.56 100.00
60 INT284433 Kdm5d Regulation of KITLG 1 0.00 0.57 0.23 100.00
61 INT335212 RDH5 Positive_regulation of NFAT5 1 0.00 0.96 0.04 100.00
62 INT335213 RDH5 Positive_regulation of CREM 1 0.00 0.96 0.04 100.00
63 INT284432 KITLG Regulation of Kdm5d 1 0.00 0.57 0.23 100.00
64 INT346134 ADM Regulation of Gene_expression of MMRN1 1 0.04 1.29 0.23 100.00
65 INT346143 ADM Regulation of Gene_expression of TPX2 1 0.02 1.29 0.23 100.00
66 INT207438 Binding of OLR1 and ERAL1 1 0.08 0.5 0.25 100.00
67 INT299745 Binding of Masp1 and IgG 1 0.03 0.69 0.26 100.00
68 INT204551 Binding of Col2a1 and Positive_regulation of Cia1 1 0.03 1.74 1.03 100.00
69 INT180564 HEYL Regulation of Regulation of DMD 1 0.00 0.88 0.28 100.00
70 INT306264 Binding of IL1A and MTX1 1 0.09 0.74 0.61 100.00
71 INT180570 Binding of HEYL and Positive_regulation of DMD 1 0.00 1.08 0.28 100.00
72 INT172138 IL17A Positive_regulation of Gene_expression of TNF 1 0.07 0.5 0.43 100.00
73 INT172149 IL17A Positive_regulation of Gene_expression of IL1B 1 0.01 0.5 0.43 100.00
74 INT207434 LPA Regulation of Gene_expression of PLA2G7 1 0.11 0.73 0.31 100.00
75 INT207391 Il17a Positive_regulation of Gene_expression of Tnfsf11 2 0.05 1.19 0.77 100.00
76 INT329568 GOPC Positive_regulation of Phosphorylation of MAPK1 1 0.04 0.79 0 100.00
77 INT207394 IL1B Positive_regulation of Gene_expression of Tnfsf11 1 0.05 0.95 0.51 100.00
78 INT207396 IL6 Positive_regulation of Gene_expression of Tnfsf11 1 0.03 0.95 0.51 100.00
79 INT329963 Binding of IL21 and IL23R 1 0.30 2.28 0.6 100.00
80 INT335215 RDH5 Positive_regulation of Negative_regulation of ERBB3 1 0.03 0.98 0 100.00
81 INT249665 Binding of GOPC and PSS 1 0.02 3.13 0.21 100.00
82 INT182952 KCNIP3 Positive_regulation of HNF4A 1 0.02 0.45 0 100.00
83 INT178593 Binding of CPOX and TPX2 1 0.02 0.88 0.12 100.00
84 INT182917 Binding of VDR and Positive_regulation of Gene_expression of CDKN1A 1 0.35 0.31 0 100.00
85 INT348175 Binding of NIDDM1 and PTPN22 1 0.01 2.36 0.99 100.00
86 INT340437 Binding of SERPINH1 and HLA-DRB4 1 0.00 2.26 0.84 100.00
87 INT194134 Binding of HLA-E and IGAD1 1 0.02 1.01 0.15 100.00
88 INT194135 Binding of CD79A and HLA-E 1 0.07 1.01 0.15 100.00
89 INT182938 Binding of HNF4A and KCNIP3 1 0.01 0.2 0 100.00
90 INT231753 Il7 Positive_regulation of TNF 1 0.03 0.66 0.39 100.00
91 INT225067 Binding of ETF1 and IGHG3 1 0.03 4.52 1.17 100.00
92 INT225065 Binding of ETF1 and FANCB 1 0.01 2.07 0.59 100.00
93 INT225082 Binding of IGHG3 and fc 6 0.01 3.6 0.55 100.00
94 INT36143 Binding of SERPINH1 and HLA-B 1 0.00 0.66 0.49 100.00
95 INT224700 TNF Positive_regulation of Angpt1 1 0.00 0.63 0.34 100.00
96 INT231797 Glrb Regulation of Negative_regulation of TNF 1 0.02 1.49 0.25 100.00
97 INT181841 Binding of CD8A and PHB2 1 0.01 0.75 0.13 100.00
98 INT271512 Binding of Glrb and Traf1 1 0.09 0.1 0.05 100.00
99 INT182902 Binding of HNF4A and KCNIP3 Positive_regulation of HNF4A 1 0.00 0.1 0 100.00
100 INT221034 IL10 Positive_regulation of Localization of CCL18 1 0.19 1.3 0.84 99.98
101 INT260833 Binding of NRP2 and Flt1 1 0.00 3.61 1.22 99.96
102 INT260842 Binding of NRP2 and Kdr 1 0.00 2.28 0.85 99.96
103 INT260832 Binding of NRP2 and Nrp1 1 0.00 2.32 0.7 99.96
104 INT254344 Binding of Col2a1 and Ncoa5 1 0.00 0.98 0.35 99.92
105 INT182813 EEF1A2 Negative_regulation of ITGAL 1 0.10 1.53 0.51 99.92
106 INT240131 Binding of Crp and Nppb 7 0.07 11.53 2.12 99.90
107 INT221026 ELANE Positive_regulation of Gene_expression of CCL18 1 0.01 0.57 0.45 99.86
108 INT264295 Binding of DMD and IGF1 1 0.07 1.38 0.44 99.84
109 INT302833 Gene_expression of Mir155 Negative_regulation of Gene_expression of Mmp3 1 0.03 1 0.57 99.84
110 INT289254 Il6 Regulation of Gene_expression of VEGFA 1 0.05 1.32 0.09 99.84
111 INT149121 Binding of CD80 and Cd28 2 0.04 0.95 0.46 99.84
112 INT329961 Binding of IL2RA and PTPN22 1 0.35 1.87 0.63 99.84
113 INT336017 Vip Regulation of Tlr4 1 0.22 1.23 0.93 99.84
114 INT59166 Binding of fc and IgG 2 0.00 1.23 0.17 99.84
115 INT285943 IL17A Positive_regulation of Localization of IL6 3 0.20 2.02 0.65 99.84
116 INT182942 VDR Positive_regulation of CDKN1A 1 0.35 0.38 0 99.84
117 INT227910 TNF Positive_regulation of Gene_expression of IL10 1 0.22 0.68 0.29 99.84
118 INT182201 Binding of CXCR5 and CXCR4 1 0.36 1.15 0.72 99.82
119 INT182202 Binding of CXCR2 and CXCR4 1 0.31 1.15 0.72 99.82
120 INT288266 Binding of AFA and CRYGD 1 0.08 1.85 0.64 99.80
121 INT45035 Binding of HLA-B and HLA-DRB4 2 0.16 0.74 0.44 99.80
122 INT182953 Binding of VDR and KCNIP3 1 0.24 0.1 0 99.80
123 INT187170 Binding of Ltbr and Tnfrsf1b 1 0.06 0.88 0.28 99.76
124 INT186128 Binding of CD2 and CD58 8 0.10 7.59 2.76 99.76
125 INT316791 Binding of HLA-DRB1 and Traf1 1 0.01 0.96 0.27 99.76
126 INT264555 IL15 Positive_regulation of Gene_expression of BCL2 1 0.02 0.92 0.35 99.76
127 INT187225 Vip Negative_regulation of Gene_expression of Tnfrsf11a 1 0.27 1.92 0.87 99.72
128 INT281981 Binding of MDK and Gtf3a 1 0.00 0.76 0.31 99.72
129 INT187227 Vip Negative_regulation of Gene_expression of Tnfsf11 1 0.35 1.23 0.51 99.72
130 INT222922 Negative_regulation of Pde4a Negative_regulation of Gene_expression of Il1 1 0.01 0.56 0.44 99.72
131 INT354455 Il11 Negative_regulation of Gene_expression of Tnf 1 0.31 1.21 0.74 99.70
132 INT333993 Binding of Vcam1 and Vwf 1 0.00 1.32 0.33 99.70
133 INT150232 Samhd1 Positive_regulation of Gene_expression of TNFSF13B 1 0.01 1.74 1.67 99.68
134 INT182022 TNF Positive_regulation of Gene_expression of Tnfrsf11b 1 0.06 1.56 0.98 99.68
135 INT182024 TNF Positive_regulation of Gene_expression of Il6 1 0.05 1.58 0.94 99.68
136 INT218309 Binding of CRP and IL6 3 0.23 4.78 1.36 99.68
137 INT262643 Binding of HLA-DQB1 and HLA-DRB1 1 0.10 0.45 0.05 99.66
138 INT27872 Positive_regulation of Binding of FCGR1B and HSPD1 1 0.01 1.93 0.56 99.64
139 INT174455 Smcp Positive_regulation of Gene_expression of Cxcr3 1 0.17 1.31 0.71 99.64
140 INT91456 IL1B Positive_regulation of Gene_expression of CPOX 6 0.17 3.36 1.53 99.64
141 INT62299 Binding of CD4 and SGCG 1 0.39 1.23 0.51 99.64
142 INT203101 Binding of Aes and Mtx1 2 0.25 0.24 0.88 99.64
143 INT187112 Binding of TIMP2 and Positive_regulation of TIMP1 1 0.32 0.26 0.1 99.64
144 INT224410 Binding of CRP and CIMT 3 0.42 10.46 1.2 99.60
145 INT297152 Binding of PRTN3 and SNRNP70 1 0.40 1.27 0.5 99.60
146 INT297153 Binding of PRTN3 and NPSR1 1 0.39 0.85 0.19 99.60
147 INT239500 Binding of Aes and Atic 1 0.20 0.4 0.56 99.60
148 INT171870 Binding of Ltbr and Sumo1 1 0.00 1.44 0.16 99.56
149 INT171871 Binding of FAS and Sumo1 1 0.02 1.43 0.16 99.56
150 INT289257 Il6 Regulation of VEGFA 1 0.03 1.27 0.09 99.56
151 INT320554 Mapk14 Positive_regulation of MEF2A 1 0.26 1.31 0 99.54
152 INT239041 Binding of Sqle and Gtf3a 1 0.00 1.08 0.27 99.54
153 INT264333 IL-17 Positive_regulation of Gene_expression of Mmp1a 1 0.05 2.88 1.18 99.52
154 INT281982 Cyp3a23/3a1 Negative_regulation of Gene_expression of MDK 1 0.00 0.67 0.47 99.50
155 INT334013 Ccl25 Positive_regulation of Gene_expression of Lrp1 1 0.07 0.98 0.56 99.48
156 INT105542 PTGES Positive_regulation of DNTT 1 0.00 0.62 0.25 99.48
157 INT27871 Binding of FCGR1B and HSPD1 1 0.01 1.93 0.56 99.44
158 INT139901 Ins1 Positive_regulation of Akt1 9 0.31 4.58 0.6 99.40
159 INT139900 Kcne2 Positive_regulation of Akt1 1 0.06 2.95 0.44 99.40
160 INT174467 IL7 Positive_regulation of IFNA1 1 0.11 1.53 0.53 99.40
161 INT240729 Binding of CRP and HLA-A 1 0.11 2.18 0.71 99.38
162 INT239503 Binding of Adora2a and Aes 1 0.24 0.85 0.35 99.36
163 INT184292 Binding of AGER and chromosomal protein 1 1 0.01 0.87 0.41 99.36
164 INT333917 MDM2 Positive_regulation of Protein_catabolism of Trp53 1 0.01 1.23 0.3 99.36
165 INT171910 MAPK1 Positive_regulation of MAPK9 1 0.10 1.55 0.52 99.36
166 INT251528 Binding of CRYGD and NEUROG1 1 0.00 0.38 0.15 99.36
167 INT171912 MAPK8IP3 Positive_regulation of MAPK9 1 0.06 0.78 0.26 99.36
168 INT171913 MAPK8 Positive_regulation of MAPK9 1 0.07 0.78 0.26 99.36
169 INT187175 Binding of BSG and PPIA 1 0.14 2.23 1.64 99.32
170 INT281970 Cyp3a23/3a1 Negative_regulation of Gene_expression of Tie1 1 0.00 0.46 0.3 99.32
171 INT240730 Binding of CRYGD and MTRF1 4 0.03 4.18 1.39 99.28
172 INT288263 Binding of AFA and MTRF1 1 0.02 1.28 0.49 99.28
173 INT36084 Binding of HLA-DRB4 and Igkv16-104 1 0.04 1.01 0.51 99.28
174 INT329448 IL17A Positive_regulation of Gene_expression of Vegfa 1 0.45 0.59 0.32 99.28
175 INT299789 IL4 Negative_regulation of Gene_expression of RAE1 1 0.00 0.84 0.41 99.28
176 INT174456 Binding of Cxcr3 and Cxcr1 1 0.31 1.24 0.58 99.24
177 INT316793 Binding of HLA-DRB1 and Stat4 1 0.07 0.33 0.08 99.24
178 INT177981 Binding of RUNX1 and SLC22A4 1 0.08 1.04 0.5 99.24
179 INT205120 Binding of CD4 and CD8A 3 0.15 2.83 0.72 99.20
180 INT178578 Binding of PTHLH and CALCRL 1 0.01 0.68 0.27 99.20
181 INT201940 Binding of IL8 and CXCL10 2 0.28 2.46 1.86 99.18
182 INT182200 Binding of CXCR5 and CXCL13 1 0.37 2.89 2.07 99.16
183 INT221031 IL10 Positive_regulation of Binding of TNF 1 0.05 0.28 0.14 99.16
184 INT176474 Binding of CXCR3 and CXCL9 3 0.22 1.9 1.05 99.12
185 INT176469 Binding of CXCL10 and CXCL9 1 0.01 0.84 0.46 99.12
186 INT174508 Binding of CD4 and HLA-B 1 0.14 4.68 1.53 99.12
187 INT174452 Binding of Cxcr2 and Cxcr3 1 0.31 1.23 0.58 99.10
188 INT174450 Positive_regulation of Binding of Cxcr3 and Smcp 1 0.18 2.83 1.49 99.08
189 INT174454 Binding of Cxcr3 and Smcp 1 0.14 1.41 0.74 99.08
190 INT183924 Binding of CHI3L1 and HLA-E 1 0.08 0.9 0.39 99.08
191 INT182912 Binding of CDKN1A and FRA8E 1 0.02 0.37 0 99.08
192 INT177977 RUNX1 Regulation of CSF1R 1 0.14 1 0.27 99.08
193 INT174468 IL7 Positive_regulation of Gene_expression of IL4 1 0.40 1.88 1.02 99.04
194 INT182124 Binding of IRF6 and TLR4 14 0.10 16.11 4.65 99.04
195 INT300544 Il22 Positive_regulation of Gene_expression of Mcpt1 1 0.02 1.15 0.47 99.04
196 INT260836 Il18 Positive_regulation of Localization of VEGFA 1 0.06 1.67 0.48 98.98
197 INT260843 Il6 Positive_regulation of Localization of VEGFA 1 0.06 1.67 0.47 98.98
198 INT260838 Il17a Positive_regulation of Localization of VEGFA 1 0.06 1.67 0.47 98.98
199 INT172137 IL11 Negative_regulation of Gene_expression of TNF 1 0.09 0.73 0.47 98.98
200 INT187117 Negative_regulation of TIMP2 Negative_regulation of MMP9 1 0.36 0.6 0.22 98.98

Single Events

The table below shows the top 200 pain related interactions that have been reported for Rheumatoid Arthritis. They are ordered first by their pain relevance and then by number of times they were reported in Rheumatoid Arthritis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 100.00
2 INT118381 Gene_expression of Il17a 405 0.76 306.97 112.06 100.00
3 INT867 Gene_expression of IFNA1 930 0.78 594.85 168.03 100.00
4 INT6481 Binding of TNF 624 0.48 510.2 214.82 100.00
5 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 100.00
6 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 100.00
7 INT6852 Localization of TNF 883 0.81 705.95 270.84 100.00
8 INT182223 Gene_expression of CXCR5 57 0.76 51.49 28.4 100.00
9 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210 100.00
10 INT145266 Gene_expression of IL17A 154 0.75 109.83 45.33 100.00
11 INT57257 Gene_expression of IL7 69 0.62 50.24 20.36 100.00
12 INT258328 Gene_expression of Aicda 76 0.71 58.29 16.86 100.00
13 INT9660 Regulation of TNF 363 0.62 312.94 139.99 100.00
14 INT10832 Gene_expression of IL8 1050 0.78 698.72 270 100.00
15 INT17612 Gene_expression of CRP 676 0.78 580.61 119.03 100.00
16 INT5058 Positive_regulation of IFNA1 356 0.70 245.75 60.52 100.00
17 INT16996 Gene_expression of PRTN3 113 0.75 85.61 22.57 100.00
18 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 100.00
19 INT143230 Gene_expression of CRYGD 61 0.65 52.11 15.93 100.00
20 INT56298 Gene_expression of IL4 306 0.78 182.18 72.92 100.00
21 INT15516 Gene_expression of Crp 711 0.77 615.33 173.09 100.00
22 INT18522 Positive_regulation of Gene_expression of IFNA1 248 0.67 160.85 44.87 100.00
23 INT140193 Gene_expression of Mmp3 58 0.71 49.65 25.4 100.00
24 INT167052 Gene_expression of Cr2 43 0.56 25.7 7.76 100.00
25 INT19428 Gene_expression of MTRF1 42 0.08 27.17 10.43 100.00
26 INT49214 Gene_expression of Cd4 269 0.78 154.22 34.05 100.00
27 INT11051 Positive_regulation of Gene_expression of IL6 415 0.69 319.21 109.3 100.00
28 INT52350 Gene_expression of CD14 184 0.75 71.37 33.13 100.00
29 INT166203 Positive_regulation of Cia1 62 0.43 75.94 31.37 100.00
30 INT132161 Gene_expression of MTX1 48 0.58 26.55 32.32 100.00
31 INT9235 Negative_regulation of Gene_expression of TNF 346 0.59 252.98 118.61 100.00
32 INT78024 Gene_expression of ACLY 73 0.75 59.15 18.54 100.00
33 INT221448 Gene_expression of CREG1 8 0.05 27.44 10.87 100.00
34 INT88318 Gene_expression of CXCR4 208 0.77 189.67 31.72 100.00
35 INT11652 Gene_expression of Rara 30 0.58 24.96 6.98 100.00
36 INT178604 Gene_expression of TPX2 13 0.37 20.29 6.04 100.00
37 INT133549 Gene_expression of Il15 42 0.69 27.84 14.74 100.00
38 INT153776 Positive_regulation of IL17A 42 0.64 34.58 14.82 100.00
39 INT11380 Negative_regulation of IL1B 215 0.59 125.62 72.35 100.00
40 INT19399 Gene_expression of Rf 43 0.36 33.39 13.53 100.00
41 INT56651 Binding of HLA-DRB1 58 0.48 52.25 13.68 100.00
42 INT151823 Binding of Tnfrsf1b 19 0.42 17.92 7.31 100.00
43 INT85015 Gene_expression of ADM 29 0.73 30.75 10.21 100.00
44 INT116282 Gene_expression of Mmp13 83 0.75 45.4 20.18 100.00
45 INT172171 Gene_expression of IL15 47 0.37 46.23 13.41 100.00
46 INT15514 Negative_regulation of Crp 275 0.59 194.6 64.86 100.00
47 INT6477 Gene_expression of IL1RN 213 0.77 114.69 58.62 100.00
48 INT62710 Gene_expression of HGF 160 0.78 88.27 26.14 100.00
49 INT60526 Gene_expression of IL10 449 0.78 292.71 107.84 100.00
50 INT169180 Binding of SNRNP70 204 0.47 119.1 29.3 100.00
51 INT145594 Gene_expression of Mtx1 64 0.57 35.33 30.35 100.00
52 INT55583 Localization of IFNA1 135 0.78 85.07 24.13 100.00
53 INT180163 Positive_regulation of Nfasc 49 0.40 31.96 9.41 100.00
54 INT63349 Gene_expression of PECAM1 199 0.75 166.03 36.76 100.00
55 INT749 Gene_expression of HLA-B 341 0.75 224.12 77.37 100.00
56 INT5328 Positive_regulation of CD4 191 0.69 133.43 21.31 100.00
57 INT353727 Gene_expression of DACT3 1 0.14 7.37 1.06 100.00
58 INT159632 Localization of DCPS 24 0.21 18.24 6.8 100.00
59 INT9234 Negative_regulation of Gene_expression of IL6 171 0.59 101.61 53.15 100.00
60 INT161515 Positive_regulation of Gene_expression of Il17a 50 0.64 41.52 13.82 100.00
61 INT11939 Negative_regulation of Il6 138 0.59 87.46 41.24 100.00
62 INT5374 Gene_expression of Esr1 412 0.77 263.89 67.34 100.00
63 INT9158 Gene_expression of Tnf 722 0.78 522.01 277.68 100.00
64 INT146808 Positive_regulation of CCL18 25 0.69 11.98 5.71 100.00
65 INT157666 Positive_regulation of GOPC 335 0.60 120.19 42.75 100.00
66 INT25607 Binding of Il1 82 0.47 64.4 23.9 100.00
67 INT171924 Gene_expression of MAPK14 60 0.65 54.38 21.68 100.00
68 INT62830 Gene_expression of VCAM1 149 0.78 125.23 32.4 100.00
69 INT99610 Localization of MMP9 126 0.79 48.46 32.67 100.00
70 INT62042 Positive_regulation of Gene_expression of IL4 67 0.56 42.05 20.39 100.00
71 INT88544 Gene_expression of MMRN1 102 0.75 68.8 14.55 100.00
72 INT9210 Regulation of IL6 166 0.62 125.61 49.95 100.00
73 INT27551 Gene_expression of SERPINH1 45 0.62 42.87 9.04 100.00
74 INT66606 Gene_expression of CXCR1 34 0.75 27.79 11.36 100.00
75 INT67457 Binding of Rara 12 0.24 8.28 1.45 100.00
76 INT174427 Positive_regulation of Gene_expression of Cxcr3 8 0.66 10.7 4.66 100.00
77 INT60691 Gene_expression of Il12a 331 0.78 208.03 75.96 100.00
78 INT150528 Positive_regulation of Gene_expression of TNFSF10 26 0.67 30.71 5.43 100.00
79 INT106745 Localization of CRP 65 0.81 66.44 15.21 100.00
80 INT9233 Negative_regulation of Gene_expression of IL1B 114 0.59 56.99 41.82 100.00
81 INT48692 Binding of VEGFA 345 0.48 210.3 21.31 100.00
82 INT135411 Gene_expression of Il23a 76 0.72 72.87 26.15 100.00
83 INT15610 Localization of GOPC 223 0.65 68.26 28.7 100.00
84 INT120811 Gene_expression of Gopc 1174 0.59 428.49 150.55 100.00
85 INT8580 Gene_expression of ELANE 132 0.75 62.98 21.79 100.00
86 INT159604 Gene_expression of IL18BP 3 0.49 4.56 2.42 100.00
87 INT73252 Positive_regulation of Mthfd1 124 0.59 59.48 18.35 100.00
88 INT187189 Positive_regulation of Gene_expression of BSG 1 0.61 6.21 5.02 100.00
89 INT28642 Gene_expression of CXCR2 60 0.78 38.69 18.11 100.00
90 INT9655 Regulation of Il6 98 0.62 70.92 31.95 100.00
91 INT86011 Gene_expression of Aldh1a2 7 0.54 6.76 0.78 100.00
92 INT143231 Positive_regulation of CRYGD 20 0.49 14.87 3.67 100.00
93 INT178606 Positive_regulation of Gene_expression of TPX2 4 0.08 8.73 2.71 100.00
94 INT8640 Positive_regulation of HSD11B1 332 0.67 377.84 22.36 100.00
95 INT67279 Localization of PRTN3 11 0.50 14.18 4.3 100.00
96 INT86705 Gene_expression of BTG3 41 0.65 37.29 8.29 100.00
97 INT170601 Positive_regulation of Gene_expression of GOPC 122 0.43 42.79 11.68 100.00
98 INT76573 Negative_regulation of Vcam1 26 0.58 24.36 9.84 100.00
99 INT58102 Binding of MTRF1 4 0.08 6.39 3.05 100.00
100 INT77652 Negative_regulation of Gene_expression of IL8 99 0.59 67.57 30.21 100.00
101 INT57258 Regulation of Gene_expression of IL7 9 0.36 4.28 2.12 100.00
102 INT34487 Localization of MMP2 56 0.81 31.41 23.61 100.00
103 INT184286 Regulation of AGER 1 0.46 6.7 3 100.00
104 INT16449 Binding of IGHG3 67 0.48 39.55 10.59 100.00
105 INT51265 Phosphorylation of TNF 32 0.81 25.33 10.75 100.00
106 INT183360 Binding of Cr2 13 0.27 7.68 2.19 100.00
107 INT182226 Regulation of Gene_expression of CXCR5 1 0.44 3.64 2.14 100.00
108 INT11699 Binding of HLA-E 85 0.47 52.51 13.41 100.00
109 INT156975 Gene_expression of SLEB1 31 0.65 38.83 6.73 100.00
110 INT9658 Negative_regulation of Gene_expression of Il6 110 0.59 66.29 32.58 100.00
111 INT159631 Positive_regulation of DCPS 60 0.27 43.23 10.3 100.00
112 INT59165 Binding of fc 67 0.36 37.51 8.68 100.00
113 INT65150 Gene_expression of Drb1 10 0.44 12.97 5.82 100.00
114 INT184284 Regulation of Gene_expression of AGER 1 0.34 4.95 2.11 100.00
115 INT36287 Binding of CD4 96 0.47 58.93 11.88 100.00
116 INT258311 Positive_regulation of Gene_expression of Aicda 9 0.60 8.51 1.74 100.00
117 INT19330 Binding of HLA-A 99 0.48 76.26 22.85 100.00
118 INT329299 Binding of RA1 6 0.35 4.52 0.35 100.00
119 INT170335 Gene_expression of INCENP 176 0.54 91.62 15.31 100.00
120 INT187187 Regulation of Gene_expression of BSG 3 0.40 3.84 2.8 100.00
121 INT3058 Gene_expression of IGKV2-19 3 0.58 4.02 0.81 100.00
122 INT91891 Gene_expression of Kit 268 0.78 158.89 22.67 100.00
123 INT335265 Gene_expression of RA1 4 0.40 5.13 0.79 100.00
124 INT153775 Positive_regulation of CTSK 9 0.52 5.44 1.9 100.00
125 INT50255 Regulation of Cd4 39 0.49 29.73 6.77 100.00
126 INT140191 Positive_regulation of Gene_expression of Mmp13 25 0.67 13.47 9.71 100.00
127 INT82829 Gene_expression of COMP 104 0.78 57 9.81 100.00
128 INT130765 Positive_regulation of ERAL1 7 0.49 7.07 1.54 100.00
129 INT250880 Gene_expression of st 1 0.01 3.25 1.63 100.00
130 INT8836 Positive_regulation of SFTPA1 36 0.47 28.37 23.59 100.00
131 INT3545 Positive_regulation of Mtx1 27 0.42 11.97 14.83 100.00
132 INT182169 Localization of IL3RA 1 0.65 2.67 1.21 100.00
133 INT192094 Binding of Rxrg 5 0.05 4.38 0.52 100.00
134 INT10836 Negative_regulation of IL8 95 0.59 52.59 24.71 100.00
135 INT136555 Negative_regulation of Tnfsf11 31 0.55 22.23 6.23 100.00
136 INT240127 Binding of Nppb 19 0.37 22.42 3.3 100.00
137 INT207443 Binding of ERAL1 5 0.19 3.69 1.47 100.00
138 INT5653 Positive_regulation of ELANE 136 0.70 72.78 27.94 100.00
139 INT182318 Regulation of Birc5 25 0.60 23.58 2.29 100.00
140 INT182168 Localization of ITGAX 3 0.73 2.71 1.17 100.00
141 INT11729 Regulation of IGF1 71 0.61 44.58 9.71 100.00
142 INT21712 Positive_regulation of APOA1 32 0.67 21.64 2.64 100.00
143 INT86024 Gene_expression of PPARA 736 0.78 497.93 91.14 100.00
144 INT68299 Binding of Tnf 17 0.39 12.55 7.49 100.00
145 INT3841 Gene_expression of FCGR3B 117 0.75 58.99 28.87 100.00
146 INT27268 Localization of Gtf3a 71 0.21 56.93 12.51 100.00
147 INT621 Positive_regulation of SERPINH1 19 0.57 21.52 8.44 100.00
148 INT258316 Binding of Aicda 1 0.30 2.24 1.08 100.00
149 INT209893 Positive_regulation of Gene_expression of TNFRSF11B 31 0.68 11.77 4.8 100.00
150 INT132860 Binding of BDNF 33 0.47 14.7 6.99 100.00
151 INT116281 Negative_regulation of Gene_expression of Mmp13 15 0.41 9.96 3.41 100.00
152 INT121337 Negative_regulation of HEY1 7 0.20 12.91 1.89 100.00
153 INT228875 Positive_regulation of RA1 4 0.29 4.13 0.92 100.00
154 INT184280 Positive_regulation of AGER 8 0.52 9.05 2.43 100.00
155 INT133156 Binding of Cd40 77 0.48 45.92 13.77 100.00
156 INT56492 Positive_regulation of ITGAX 2 0.49 2.95 1.14 100.00
157 INT37618 Gene_expression of Col2a1 50 0.70 33.88 11.58 100.00
158 INT92354 Localization of ESR1 77 0.75 33.04 15.51 100.00
159 INT284028 Gene_expression of Dhdds 1 0.21 2.76 1.11 100.00
160 INT278722 Phosphorylation of ERAL1 1 0.10 3.19 1.21 100.00
161 INT52625 Regulation of IL1RN 30 0.61 19.12 11.31 100.00
162 INT46849 Regulation of TPX2 5 0.24 6.27 2.1 100.00
163 INT194892 Regulation of Mmp1a 5 0.22 4.93 2.67 100.00
164 INT52531 Gene_expression of Nfkb1 153 0.75 82.84 42.9 100.00
165 INT194609 Regulation of Gene_expression of Il15 1 0.18 3.33 1.86 100.00
166 INT5587 Regulation of Fos 191 0.62 40.81 99.7 100.00
167 INT353726 Positive_regulation of DACT3 1 0.11 2.47 0.53 100.00
168 INT259489 Binding of DLK1 1 0.45 6.52 0.21 100.00
169 INT86006 Gene_expression of Aldh1a1 5 0.53 3.22 0.43 100.00
170 INT174430 Regulation of Cxcr1 1 0.21 5.03 1.73 100.00
171 INT167039 Gene_expression of Cd74 24 0.40 17.12 2.84 100.00
172 INT73836 Regulation of Comp 4 0.19 4.2 2.79 100.00
173 INT2609 Localization of ELANE 111 0.81 50.22 26.63 100.00
174 INT184273 Localization of AGER 1 0.60 3.59 1.67 100.00
175 INT65489 Regulation of Gene_expression of Crp 28 0.59 29.17 7.56 100.00
176 INT14281 Gene_expression of Hspa5 44 0.63 34.19 3.31 100.00
177 INT335263 Localization of RA1 3 0.47 3.04 0.52 100.00
178 INT3055 Binding of OLAH 9 0.28 7.14 3.99 100.00
179 INT187289 Regulation of HEY1 5 0.39 7.8 1.03 100.00
180 INT207445 Positive_regulation of PLA2G7 7 0.63 7.66 1 100.00
181 INT162258 Negative_regulation of Gene_expression of COMP 35 0.58 19.14 3.55 100.00
182 INT64473 Regulation of Gene_expression of IL4 17 0.58 6.61 3.96 100.00
183 INT156689 Regulation of CD177 2 0.01 1.76 1.16 100.00
184 INT102452 Gene_expression of RAMP2 6 0.69 7.11 3.77 100.00
185 INT335795 Regulation of Localization of RA1 2 0.26 2.7 0.53 100.00
186 INT92199 Negative_regulation of Gene_expression of IL1RN 14 0.58 10.11 4.71 100.00
187 INT258307 Positive_regulation of Gene_expression of Cr2 1 0.36 1.72 0.69 100.00
188 INT258321 Regulation of Gene_expression of Aicda 1 0.42 1.47 0.75 100.00
189 INT756 Gene_expression of C3 138 0.75 100.6 19.2 100.00
190 INT34485 Negative_regulation of Localization of MMP2 17 0.50 9.96 10.49 100.00
191 INT11938 Positive_regulation of Localization of Il6 61 0.70 35.72 18.25 100.00
192 INT11030 Binding of LPA 70 0.48 40.35 4.81 100.00
193 INT86805 Localization of HGF 49 0.71 28.48 6.35 100.00
194 INT28249 Positive_regulation of HLA-DRA 25 0.70 13.63 3.25 100.00
195 INT284035 Regulation of Gene_expression of Sh4 1 0.58 3.14 1.11 100.00
196 INT260874 Positive_regulation of Binding of SNRNP70 3 0.49 2.17 0.91 100.00
197 INT3898 Positive_regulation of st 8 0.14 4.48 1.44 100.00
198 INT200470 Positive_regulation of Gene_expression of COMP 13 0.69 13.73 2.93 100.00
199 INT16405 Regulation of CD8A 38 0.45 19.04 5.31 100.00
200 INT25394 Negative_regulation of Gene_expression of Csf2 22 0.52 13.18 5.84 100.00
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