D:Right Ventricular Hypertrophy

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Disease Term
Synonyms HYPERTROPHIES RIGHT VENTRICULAR, Right Ventricular Hypertrophies, Ventricular Hypertrophies Right, Ventricular Hypertrophy Right
Documents 78
Hot Single Events 49
Hot Interactions 3

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Right Ventricular Hypertrophy. They are ordered first by their relevance to Right Ventricular Hypertrophy and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT284139 EDNRB Positive_regulation of Gene_expression of EDNRA 1 0.12 0.45 0.22 97.78
2 INT284142 ERAS Regulation of PAH 1 0.10 0.55 0.2 82.60
3 INT284138 ERAS Regulation of Positive_regulation of PAH 1 0.10 0.55 0.2 82.60
4 INT230724 EDN1 Positive_regulation of EDNRA 3 0.24 4.12 0.39 39.88
5 INT54972 Binding of EDNRA and EDNRB 7 0.52 3.31 0.97 31.28
6 INT261606 Il6 Regulation of Gene_expression of smc 1 0.03 0 0 29.36
7 INT160515 Negative_regulation of Sert1 Negative_regulation of Pah 1 0.34 0.84 0.19 25.00
8 INT230734 Negative_regulation of Binding of EDNRA and Pah 1 0.02 3.26 0.61 11.16
9 INT230735 Binding of EDNRA and Pah 1 0.02 3.22 0.6 9.80
10 INT188318 MCPH1 Positive_regulation of Pah 3 0.02 3 0.85 5.00
11 INT278827 Binding of EDN1 and EDNRB 3 0.17 2.7 0.67 5.00
12 INT178097 Binding of EDN1 and EDNRA 7 0.21 5.97 0.62 5.00
13 INT261608 Il6 Negative_regulation of Gene_expression of TNF 1 0.03 1.27 0.53 5.00
14 INT278825 Positive_regulation of Binding of EDN1 and EDNRB 3 0.16 1.24 0.49 5.00
15 INT261603 Il6 Regulation of Gene_expression of Vcam1 1 0.16 1.74 0.46 5.00
16 INT273617 Gene_expression of Slc6a4 Positive_regulation of Pah 1 0.02 0.93 0.38 5.00
17 INT261597 Binding of PAH and COPD 1 0.00 1.08 0.34 5.00
18 INT284137 EDNRB Regulation of EDNRA 1 0.07 0.09 0.3 5.00
19 INT261605 Il6 Regulation of smc 1 0.02 1.19 0.3 5.00
20 INT261609 Binding of PAH and Hypt 1 0.00 1.26 0.28 5.00
21 INT271071 Binding of ACTA1 and Hypism 1 0.00 1.54 0.15 5.00
22 INT284140 Binding of EDNRB and PAH 1 0.08 0.1 0.1 5.00
23 INT284141 Binding of EDNRA and PAH 1 0.05 0.1 0.09 5.00
24 INT273616 PVR Positive_regulation of Pah 1 0.10 0.86 0.07 5.00
25 INT261607 Il6 Positive_regulation of smc 1 0.03 0.3 0.05 5.00
26 INT261604 Positive_regulation of Il6 Positive_regulation of smc 1 0.03 0.3 0.05 5.00
27 INT352175 USE1 Regulation of NAGA 1 0.01 0.33 0 5.00
28 INT284143 EDN1 Positive_regulation of CA2 1 0.03 0.37 0 5.00
29 INT309846 Binding of pad and Pah 1 0.03 0.98 0 5.00
30 INT230723 ERVW-1 Positive_regulation of Gene_expression of EDN1 1 0.00 1.95 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Right Ventricular Hypertrophy. They are ordered first by their pain relevance and then by number of times they were reported in Right Ventricular Hypertrophy. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT79349 Gene_expression of Sert1 58 0.77 12.7 20.65 99.78
2 INT79347 Regulation of Gene_expression of Sert1 9 0.54 2.57 3.58 99.78
3 INT71789 Positive_regulation of MAPK1 396 0.70 234.44 89.27 99.72
4 INT9131 Positive_regulation of Prkcg 431 0.70 130.8 302.41 99.40
5 INT1912 Gene_expression of Calca 1152 0.78 453.25 739.84 99.34
6 INT12536 Localization of Prkcg 101 0.80 36.37 73.81 98.48
7 INT7362 Gene_expression of Sst 185 0.78 41.73 111.37 98.48
8 INT8368 Binding of Nka1 12 0.34 1.66 6.3 97.32
9 INT23937 Gene_expression of EDNRA 103 0.65 55.63 24.67 97.06
10 INT83199 Gene_expression of Nos3 193 0.78 100.72 51.57 95.92
11 INT90675 Negative_regulation of Gene_expression of Nos3 15 0.46 11.11 2.7 95.92
12 INT22965 Positive_regulation of Pah 42 0.61 41.41 8.84 95.24
13 INT2649 Regulation of Calca 433 0.62 146.05 330.95 95.16
14 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74 94.56
15 INT9110 Binding of PAH 32 0.41 42.1 3.1 94.56
16 INT11939 Negative_regulation of Il6 138 0.59 87.46 41.24 94.24
17 INT8243 Positive_regulation of Il6 451 0.70 358.24 119.28 94.00
18 INT128921 Negative_regulation of Gene_expression of Ephb1 18 0.49 9.54 14.93 93.48
19 INT106759 Negative_regulation of Gene_expression of Dusp1 2 0.36 0.59 0.3 93.48
20 INT48923 Gene_expression of Ephb1 211 0.77 106.23 109.9 92.84
21 INT106757 Gene_expression of Dusp1 9 0.66 10.45 7.26 92.84
22 INT8905 Gene_expression of EDN1 215 0.78 157.1 34.19 91.40
23 INT75440 Regulation of Binding of Edn1 4 0.38 1.41 4.33 90.56
24 INT5048 Binding of Edn1 55 0.47 18.86 19.16 90.56
25 INT49468 Negative_regulation of Pah 28 0.55 24.95 6.29 90.24
26 INT17879 Positive_regulation of Ppap2a 17 0.53 9.72 3.8 89.80
27 INT5061 Negative_regulation of Mme 306 0.59 51.97 136.9 89.76
28 INT32783 Gene_expression of Pah 33 0.60 30.55 6.86 89.76
29 INT47743 Negative_regulation of Slc6a4 22 0.59 6.23 12.23 89.76
30 INT91462 Positive_regulation of Phosphorylation of MAPK1 99 0.67 40.28 18.99 89.56
31 INT4759 Negative_regulation of Localization of Calca 294 0.59 82.62 226.45 89.56
32 INT284147 Positive_regulation of MYH7 1 0.12 0.52 0.21 89.20
33 INT71786 Phosphorylation of MAPK1 256 0.82 110.09 46.17 89.16
34 INT2542 Localization of Calca 2008 0.81 518.3 1408.65 89.00
35 INT5781 Gene_expression of Edn1 190 0.78 99.1 46 87.48
36 INT70907 Negative_regulation of EDNRA 30 0.36 19.68 5.49 86.88
37 INT38971 Positive_regulation of Gene_expression of Gtf3a 27 0.60 18.25 7.77 86.72
38 INT68279 Positive_regulation of Gene_expression of Csf2 30 0.67 16.31 6.88 86.72
39 INT9657 Positive_regulation of Gene_expression of Il6 237 0.70 180.45 63.6 86.44
40 INT9659 Gene_expression of Il6 991 0.78 715.11 265.57 85.76
41 INT4345 Gene_expression of Gtf3a 157 0.67 80.75 48.47 84.92
42 INT22939 Gene_expression of Csf2 164 0.78 85.1 32.22 84.64
43 INT127458 Positive_regulation of PAH 24 0.58 27.25 2.53 84.32
44 INT8662 Positive_regulation of EDN1 144 0.70 125.34 19.59 84.16
45 INT12537 Positive_regulation of Localization of Prkcg 36 0.70 14.57 33.81 83.20
46 INT4721 Negative_regulation of Nka1 17 0.59 2.08 9.57 81.80
47 INT171715 Gene_expression of Sema5b 46 0.31 6.46 7.48 81.68
48 INT261601 Binding of Emr1 2 0.02 1.34 0.08 80.88
49 INT65211 Binding of Prkcg 38 0.48 14.75 16.92 80.28
50 INT79348 Positive_regulation of Sert1 11 0.64 4.32 6.17 79.48
51 INT8661 Positive_regulation of Positive_regulation of EDN1 10 0.66 10.9 1.76 79.04
52 INT12763 Phosphorylation of Prkcg 167 0.82 38.91 89.63 78.68
53 INT63934 Phosphorylation of Ephb1 377 0.82 150.52 188.66 78.40
54 INT63936 Positive_regulation of Phosphorylation of Ephb1 131 0.70 49.38 73.16 78.40
55 INT114498 Positive_regulation of MCPH1 10 0.43 5.82 0.91 78.08
56 INT175688 Gene_expression of smc 23 0.16 8.72 1.54 77.68
57 INT246445 Positive_regulation of Gene_expression of smc 2 0.10 2.12 0.19 77.68
58 INT63932 Positive_regulation of Ephb1 537 0.70 259.67 296.14 77.40
59 INT261600 Positive_regulation of Gene_expression of Il6ra 7 0.05 6.22 0.84 76.32
60 INT178127 Positive_regulation of Gene_expression of EDNRB 7 0.51 5.24 0.78 75.28
61 INT127460 Positive_regulation of Gene_expression of PAH 5 0.43 4.3 0.5 75.28
62 INT75531 Regulation of MAPK1 70 0.61 34.39 15.42 75.00
63 INT50058 Negative_regulation of Cpox 907 0.58 426.28 428.29 75.00
64 INT51921 Gene_expression of Cpox 501 0.73 229.81 157.81 75.00
65 INT160814 Gene_expression of Il6ra 15 0.07 9.61 1.73 74.88
66 INT102722 Phosphorylation of PDPK1 3 0.82 1.39 0.4 74.24
67 INT119523 Gene_expression of EDNRB 32 0.75 26.47 5.75 73.56
68 INT19158 Gene_expression of PAH 35 0.65 35.81 3.88 73.56
69 INT79345 Positive_regulation of Gene_expression of Sert1 8 0.58 2.98 3.26 73.20
70 INT45342 Binding of AVSD1 6 0.31 7.23 0.27 72.96
71 INT6133 Negative_regulation of Serpinc1 56 0.58 42.8 8.35 71.52
72 INT27813 Regulation of CENPJ 12 0.29 14.26 0.99 71.44
73 INT106756 Positive_regulation of Gene_expression of Dusp1 7 0.59 7.65 5.24 71.00
74 INT106760 Positive_regulation of Dusp1 16 0.59 8.5 3.35 70.20
75 INT47243 Gene_expression of Prkcg 195 0.78 58.05 108.44 69.52
76 INT51698 Positive_regulation of Gene_expression of Prkcg 44 0.68 14.02 32.9 69.28
77 INT163969 Positive_regulation of Hypt 6 0.41 6.24 0.49 66.72
78 INT53500 Negative_regulation of Ppap2a 11 0.45 3.31 1.92 65.04
79 INT11077 Positive_regulation of Htr3a 63 0.67 15.61 22.7 63.84
80 INT163913 Gene_expression of Il11ra1 18 0.69 12.62 5.34 62.92
81 INT261598 Positive_regulation of Transcription of Icam1 3 0.24 2.56 0.55 61.92
82 INT110768 Transcription of Mcpt1 12 0.52 7.66 4.71 61.92
83 INT17802 Transcription of Edn1 6 0.24 6.31 1.18 61.92
84 INT261599 Transcription of Icam1 6 0.50 4.55 1.07 61.92
85 INT83946 Transcription of Vcam1 2 0.40 3.33 0.95 61.92
86 INT177643 Binding of CENPJ 12 0.36 8.59 0.22 59.32
87 INT9191 Localization of EDN1 94 0.81 57.01 14.78 58.08
88 INT39777 Regulation of Prkcg 90 0.62 31.52 68.17 57.84
89 INT183568 Negative_regulation of Protein_catabolism of Prkcg 2 0.36 1.12 1.33 57.20
90 INT181668 Protein_catabolism of Prkcg 8 0.77 2.59 3.06 57.00
91 INT35349 Gene_expression of CENPJ 52 0.57 25.36 2.54 56.72
92 INT127459 Negative_regulation of PAH 18 0.56 15.15 1.05 55.60
93 INT79395 Gene_expression of Twist1 193 0.77 100.06 26.34 54.60
94 INT169725 Binding of Il6ra 4 0.07 3.99 0.59 53.36
95 INT54763 Binding of Il6 82 0.48 63.27 12.89 52.64
96 INT48959 Positive_regulation of Positive_regulation of Prkcg 52 0.70 16.47 36.49 50.00
97 INT63854 Regulation of Gene_expression of Prkcg 27 0.56 9.41 14.15 50.00
98 INT65210 Positive_regulation of Binding of Prkcg 6 0.70 2.71 3.65 50.00
99 INT109906 Localization of MAPK1 12 0.54 1.68 2.01 50.00
100 INT183569 Negative_regulation of Binding of Prkcg 1 0.05 0.69 0 50.00
101 INT49985 Transcription of Il6 62 0.72 40.13 20.29 49.72
102 INT66924 Positive_regulation of Transcription of Il6 18 0.68 11.8 3.53 49.72
103 INT121774 Binding of ACTA1 4 0.47 2.31 0.85 45.44
104 INT132662 Binding of Hcm 11 0.31 14.41 0.73 44.92
105 INT188316 Positive_regulation of Positive_regulation of MCPH1 1 0.02 0.73 0.04 44.64
106 INT139515 Positive_regulation of EDNRB 15 0.67 10.35 0.93 43.20
107 INT177642 Positive_regulation of Gene_expression of CENPJ 5 0.30 3.25 0.07 43.16
108 INT273614 Regulation of PVR 1 0.17 0.84 0.14 43.04
109 INT9231 Binding of Htr3a 27 0.47 7.29 13.04 42.28
110 INT29651 Regulation of Pah 11 0.37 9.95 2.79 41.20
111 INT18025 Binding of Pah 32 0.45 30.72 7.93 36.04
112 INT6726 Positive_regulation of Edn1 118 0.70 65.96 24.07 34.32
113 INT177683 Negative_regulation of Gene_expression of CENPJ 5 0.32 4.27 0.03 32.28
114 INT203637 Binding of CD2AP 1 0.04 0.57 0.03 25.92
115 INT160514 Regulation of Positive_regulation of Pah 1 0.22 1.62 0.45 25.20
116 INT29086 Negative_regulation of Sert1 37 0.58 7.49 14.98 25.00
117 INT124496 Regulation of Negative_regulation of Sert1 2 0.39 1.31 0.64 25.00
118 INT63351 Negative_regulation of Gene_expression of PECAM1 19 0.52 16.06 5.73 24.00
119 INT11936 Positive_regulation of Positive_regulation of Il6 34 0.50 26.85 10.59 23.08
120 INT17824 Positive_regulation of Gene_expression of Flvcr2 15 0.41 6.66 10.23 22.76
121 INT17825 Gene_expression of Flvcr2 44 0.68 12.58 28.08 22.36
122 INT87632 Positive_regulation of Gene_expression of PECAM1 32 0.45 29.47 4.66 19.92
123 INT70615 Binding of TXNRD1 25 0.36 12.15 1.27 19.76
124 INT63349 Gene_expression of PECAM1 199 0.75 166.03 36.76 19.28
125 INT76713 Regulation of Gene_expression of PECAM1 16 0.40 14.52 2.51 19.28
126 INT36978 Localization of Pah 9 0.73 7.43 0.82 18.72
127 INT20612 Positive_regulation of Asap1 36 0.68 24.35 6.06 17.44
128 INT19541 Gene_expression of Ptgir 22 0.65 15.42 5.39 16.00
129 INT90909 Negative_regulation of Gene_expression of NOS1 44 0.55 23.83 12.47 14.28
130 INT62124 Gene_expression of NOS1 444 0.78 218.08 114.85 12.96
131 INT203636 Positive_regulation of CD2AP 4 0.13 1.27 0.28 12.32
132 INT7894 Negative_regulation of Vip 59 0.59 11.76 27.36 12.12
133 INT125775 Positive_regulation of Serpinb2 7 0.36 3.81 0.9 6.08
134 INT156685 Regulation of ASAP1 8 0.22 1.94 0.71 5.96
135 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 5.00
136 INT19472 Gene_expression of Il1 554 0.76 419.75 175.35 5.00
137 INT15516 Gene_expression of Crp 711 0.77 615.33 173.09 5.00
138 INT9852 Positive_regulation of Gpt 563 0.70 364.64 146.82 5.00
139 INT1635 Gene_expression of Vip 245 0.78 53.36 88.13 5.00
140 INT10534 Positive_regulation of Trib3 209 0.60 78.75 81.48 5.00
141 INT1724 Negative_regulation of ACE 437 0.59 315.64 74.48 5.00
142 INT11937 Localization of Il6 228 0.81 139.83 64.39 5.00
143 INT62543 Gene_expression of Icam1 231 0.78 187.58 52.71 5.00
144 INT72182 Gene_expression of Mcpt1 167 0.75 123.7 52.15 5.00
145 INT2604 Positive_regulation of Got1 223 0.70 154.78 49.51 5.00
146 INT51163 Gene_expression of Gal 119 0.78 67.48 49.23 5.00
147 INT6979 Positive_regulation of CA2 206 0.67 50.79 44.97 5.00
148 INT68975 Gene_expression of Mmp9 111 0.78 79.57 38.55 5.00
149 INT60710 Gene_expression of Col7a1 217 0.78 113.2 35.2 5.00
150 INT65055 Negative_regulation of Nfkb1 83 0.58 44.85 34.94 5.00
151 INT5489 Localization of CA2 172 0.80 39.46 33.56 5.00
152 INT63935 Positive_regulation of Gene_expression of Ephb1 52 0.61 24.3 33.05 5.00
153 INT9658 Negative_regulation of Gene_expression of Il6 110 0.59 66.29 32.58 5.00
154 INT9655 Regulation of Il6 98 0.62 70.92 31.95 5.00
155 INT29503 Gene_expression of Mmp2 95 0.77 56.92 31.68 5.00
156 INT68973 Positive_regulation of Mmp9 89 0.52 58.56 30.04 5.00
157 INT15610 Localization of GOPC 223 0.65 68.26 28.7 5.00
158 INT6364 Gene_expression of Edn1 123 0.78 73.76 28.43 5.00
159 INT22211 Positive_regulation of CYP3A4 110 0.70 22 28.27 5.00
160 INT10799 Localization of ENG 63 0.78 18.67 27.28 5.00
161 INT2040 Positive_regulation of CYP2B6 95 0.69 34.3 25.6 5.00
162 INT73670 Gene_expression of Vcam1 128 0.78 123.79 24.96 5.00
163 INT76743 Gene_expression of Slc6a4 55 0.76 13.53 24.9 5.00
164 INT58288 Positive_regulation of Gene_expression of Crp 83 0.61 82.23 23.7 5.00
165 INT74682 Positive_regulation of Mmp2 72 0.69 40.46 21.73 5.00
166 INT76336 Negative_regulation of PDE5A 192 0.59 112.02 20.09 5.00
167 INT5398 Positive_regulation of ALPP 178 0.70 110.52 19.18 5.00
168 INT9230 Gene_expression of Htr3a 43 0.78 10.54 18.81 5.00
169 INT14306 Positive_regulation of Gal 36 0.70 21.66 18.51 5.00
170 INT9656 Regulation of Gene_expression of Il6 57 0.62 33.3 17.71 5.00
171 INT6728 Gene_expression of Ednra 43 0.65 13.41 17.38 5.00
172 INT9069 Regulation of Htr3a 29 0.60 6.18 16.55 5.00
173 INT20611 Gene_expression of Asap1 55 0.65 23.71 14.62 5.00
174 INT11340 Positive_regulation of SLC17A5 120 0.67 113.52 14.5 5.00
175 INT8904 Positive_regulation of Gene_expression of EDN1 66 0.70 65.4 14.42 5.00
176 INT18773 Localization of ALB 117 0.80 69.18 13.8 5.00
177 INT86383 Negative_regulation of EGFR 258 0.59 173.94 13.32 5.00
178 INT13823 Gene_expression of Egf 97 0.78 39.99 12.99 5.00
179 INT21979 Negative_regulation of EDN1 52 0.58 24.65 12.55 5.00
180 INT11793 Negative_regulation of CA2 78 0.57 19.63 12.35 5.00
181 INT9832 Gene_expression of Shbg 96 0.75 56.71 12.19 5.00
182 INT70905 Positive_regulation of EDNRA 49 0.67 24.33 11.79 5.00
183 INT10874 Negative_regulation of Twist1 89 0.50 36.84 11.32 5.00
184 INT68976 Positive_regulation of Gene_expression of Mmp9 34 0.42 28.21 11.28 5.00
185 INT52233 Transcription of Jun 37 0.66 6.39 11.15 5.00
186 INT74681 Positive_regulation of Gene_expression of Mmp2 23 0.55 15.58 10.74 5.00
187 INT9550 Gene_expression of TNNI3 113 0.78 86.79 10.56 5.00
188 INT94859 Negative_regulation of Pde5a 67 0.43 33.66 10.28 5.00
189 INT10184 Regulation of EDN1 44 0.62 23.78 10.06 5.00
190 INT15449 Positive_regulation of Plat 32 0.69 12.76 9.71 5.00
191 INT55014 Positive_regulation of Ednrb 31 0.70 16.61 9.68 5.00
192 INT48978 Negative_regulation of FOS 41 0.57 11.94 9.14 5.00
193 INT9548 Gene_expression of CHKB 99 0.65 50.86 9.03 5.00
194 INT7105 Gene_expression of pad 54 0.77 63.68 8.8 5.00
195 INT6727 Positive_regulation of Ednra 27 0.64 18.75 8.71 5.00
196 INT10237 Binding of EDN1 40 0.48 16 8.48 5.00
197 INT51165 Binding of Gal 10 0.48 2.56 8.41 5.00
198 INT61599 Positive_regulation of CYP2C9 43 0.69 11.1 8.33 5.00
199 INT62944 Regulation of Icam1 33 0.47 23.52 7.94 5.00
200 INT54978 Binding of EDNRA 36 0.41 14.97 7.86 5.00
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