D:Root Caries

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Disease Term
Synonyms Caries Cervical, Caries Root, Cary Cervical, CERVICAL CARIES, Cervical Cary
Documents 25
Hot Single Events 5
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Root Caries. They are ordered first by their relevance to Root Caries and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT288983 Binding of DEFB1 and HPR 1 0.01 0 0 5.00
2 INT288982 Binding of CD79A and SFTPA2 1 0.00 0.06 0 5.00
3 INT288981 Binding of DEFB1 and PTPN22 1 0.11 0 0 5.00
4 INT288984 DEFB1 Positive_regulation of GGH 1 0.01 0 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Root Caries. They are ordered first by their pain relevance and then by number of times they were reported in Root Caries. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT212930 Localization of ELL 2 0.15 0.87 0.04 93.24
2 INT93715 Negative_regulation of MMP9 69 0.55 36.05 11.73 89.80
3 INT34488 Negative_regulation of MMP2 85 0.59 41.98 21.72 89.40
4 INT142732 Negative_regulation of STATH 3 0.42 1.72 0.16 86.56
5 INT158540 Negative_regulation of HTN1 4 0.34 7.25 1.22 85.44
6 INT96579 Negative_regulation of Negative_regulation of MMP9 5 0.40 4.55 1.04 75.00
7 INT96581 Negative_regulation of Negative_regulation of MMP2 4 0.57 3.1 1.04 75.00
8 INT96580 Negative_regulation of Protein_catabolism of MMP2 2 0.55 0.6 0.51 66.84
9 INT96582 Negative_regulation of Protein_catabolism of COL1A2 1 0.37 0.2 0.21 66.84
10 INT90202 Protein_catabolism of MMP2 15 0.94 7.47 5.41 66.28
11 INT49238 Protein_catabolism of COL1A2 30 0.97 15.64 3.45 66.28
12 INT3758 Gene_expression of ALB 326 0.78 184.65 38.75 48.92
13 INT8580 Gene_expression of ELANE 132 0.75 62.98 21.79 48.92
14 INT4391 Gene_expression of SERPINA1 47 0.78 41.43 9.7 48.92
15 INT10141 Gene_expression of A2M 11 0.35 9.37 2.75 48.92
16 INT69264 Gene_expression of KIT 207 0.78 179.41 8.95 42.72
17 INT25585 Positive_regulation of DNAH8 39 0.70 17.96 7.85 5.00
18 INT72219 Gene_expression of METTL3 45 0.24 9.58 7.61 5.00
19 INT1124 Negative_regulation of CD40LG 53 0.57 36.26 7 5.00
20 INT1126 Negative_regulation of CD79A 46 0.59 31.07 6 5.00
21 INT28030 Binding of Otc 5 0.37 2.72 4.3 5.00
22 INT82871 Protein_catabolism of MMP1 13 0.96 10.71 4.09 5.00
23 INT9884 Localization of CD79A 41 0.78 21.75 3.06 5.00
24 INT120515 Gene_expression of Otc 13 0.66 4.33 2.6 5.00
25 INT32431 Gene_expression of HTC2 17 0.75 9.72 1.93 5.00
26 INT47615 Negative_regulation of DNASE1 9 0.58 3.62 1.74 5.00
27 INT125007 Gene_expression of DEFB1 30 0.60 4.14 1.32 5.00
28 INT157372 Gene_expression of MAP4K1 11 0.78 10.03 1.2 5.00
29 INT72218 Regulation of METTL3 5 0.08 1.62 1.14 5.00
30 INT120514 Negative_regulation of Gene_expression of Otc 4 0.41 1.19 1.08 5.00
31 INT123144 Positive_regulation of DEFB1 4 0.45 2.12 1.08 5.00
32 INT5679 Negative_regulation of RNASE1 7 0.40 2.39 1 5.00
33 INT29788 Gene_expression of DNASE1L1 3 0.03 0.61 0.99 5.00
34 INT91160 Binding of DMBT1 9 0.26 3.12 0.37 5.00
35 INT186921 Protein_catabolism of DEFB1 9 0.23 1.85 0.35 5.00
36 INT263021 Transcription of DEFB1 2 0.21 0.8 0.32 5.00
37 INT204363 Gene_expression of VIS1 6 0.19 2.49 0.21 5.00
38 INT32032 Gene_expression of DMBT1 3 0.04 2.43 0.2 5.00
39 INT15385 Negative_regulation of Negative_regulation of CD79A 2 0.41 3.05 0.17 5.00
40 INT125008 Negative_regulation of DEFB1 2 0.40 0.19 0.07 5.00
41 INT268406 Positive_regulation of MYLIP 1 0.01 0.9 0.04 5.00
42 INT268403 Positive_regulation of SCAP 2 0.01 1.22 0.04 5.00
43 INT288960 Gene_expression of RBKS 1 0.07 0.13 0.03 5.00
44 INT268402 Positive_regulation of DMBT1 1 0.04 0.88 0.03 5.00
45 INT268407 Negative_regulation of Localization of CD79A 1 0.10 0.84 0.03 5.00
46 INT268405 Positive_regulation of ISG15 2 0.27 1.14 0 5.00
47 INT268410 Positive_regulation of MKS1 1 0.03 0 0 5.00
48 INT268404 Regulation of MKS1 1 0.04 1.15 0 5.00
49 INT268409 Protein_catabolism of DMBT1 1 0.04 0.09 0 5.00
50 INT268408 Transcription of MKS1 1 0.04 0.1 0 5.00
51 INT212929 Positive_regulation of CAPNS2 1 0.42 0.51 0 5.00
52 INT252000 Negative_regulation of FH 4 0.37 1.44 0 5.00
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