D:Rupture

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pChart

Disease Term
Synonyms RUPTURES
Documents 5854
Hot Single Events 200
Hot Interactions 66

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Rupture. They are ordered first by their relevance to Rupture and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT302467 TIMP1 Positive_regulation of Negative_regulation of COL5A2 1 0.00 1.1 0.29 100.00
2 INT127664 Negative_regulation of PDE4A Negative_regulation of MMP9 1 0.37 0.76 0.48 100.00
3 INT127665 Negative_regulation of PDE4A Negative_regulation of Transcription of MMP9 1 0.37 0.76 0.48 100.00
4 INT285748 PRL Positive_regulation of Positive_regulation of C6orf25 1 0.01 1.01 0.31 100.00
5 INT319753 Mpo Positive_regulation of Timp1 1 0.14 2.13 0.29 99.60
6 INT140168 Binding of Cx3cl1 and Cx3cr1 2 0.31 1.55 0.98 99.12
7 INT165101 Positive_regulation of Binding of Cx3cl1 and Cx3cr1 1 0.13 0.39 0.2 99.12
8 INT242025 Binding of CRP and CHDH 7 0.18 15.72 0.36 98.94
9 INT271355 PGF Positive_regulation of PIGF 1 0.01 0.99 0.06 98.72
10 INT271350 MPO Positive_regulation of TIMP1 1 0.05 1.66 0.29 98.68
11 INT230751 Agtr2 Positive_regulation of Gene_expression of Serpine1 1 0.03 1.3 0.23 98.64
12 INT242023 Binding of CHDH and CIMT 1 0.09 1.01 0 98.10
13 INT312802 F2 Positive_regulation of Binding of NPEPPS 1 0.01 1.33 0.32 97.00
14 INT209155 MMP9 Negative_regulation of TIMP1 1 0.01 0.17 0.05 96.96
15 INT209156 MMP2 Negative_regulation of TIMP1 1 0.00 0.17 0.05 96.96
16 INT127662 Negative_regulation of PDE4A Negative_regulation of Gene_expression of PTGS2 1 0.15 0.75 0.47 96.80
17 INT312803 F2 Positive_regulation of NPEPPS 1 0.01 1.32 0.32 96.64
18 INT247079 Gene_expression of PLAT Positive_regulation of Gene_expression of PLG 1 0.36 0.3 0.07 96.60
19 INT114809 Selp Positive_regulation of Gene_expression of F3 1 0.00 0.88 0.34 96.16
20 INT142076 IL4 Negative_regulation of Gene_expression of IFNG 1 0.01 1.58 0.64 95.52
21 INT209157 MMP9 Negative_regulation of MMP2 1 0.00 0.16 0.05 95.24
22 INT336751 Binding of Selp and Cd40 1 0.03 2.49 0.18 94.56
23 INT278399 Syk Positive_regulation of Localization of Ctsb 1 0.09 0.28 0 94.28
24 INT71310 Il1a Positive_regulation of NOS1 1 0.07 0.09 0.11 94.28
25 INT71311 Il1a Positive_regulation of Positive_regulation of NOS1 1 0.07 0.09 0.11 94.28
26 INT345060 Binding of SGCG and C2 1 0.00 0.93 0 94.08
27 INT266659 Binding of MMP9 and MOCS1 1 0.01 1.71 0.94 93.84
28 INT288908 Apoa1 Positive_regulation of Gene_expression of HSD11B1 1 0.03 0.53 0.04 92.64
29 INT266080 Binding of PAPPA and MUC16 1 0.40 0.74 0 92.32
30 INT242883 INS Negative_regulation of Gene_expression of TLR2 1 0.17 2.35 0.6 91.44
31 INT242875 INS Negative_regulation of Gene_expression of TLR4 1 0.11 1.41 0.24 91.44
32 INT266068 Binding of CHKB and MUC16 1 0.22 0.74 0 91.40
33 INT221249 Hspa9 Negative_regulation of Gene_expression of Ros1 1 0.01 0.91 0 90.08
34 INT221241 Sf3a2 Negative_regulation of Gene_expression of Ros1 1 0.00 0.91 0 90.08
35 INT71309 Il1a Positive_regulation of Nos2 1 0.21 0.26 0.26 89.76
36 INT278403 Hps5 Positive_regulation of Il1 1 0.04 1.48 0.24 89.44
37 INT250913 Col7a1 Regulation of Thbs2 Regulation of Col7a1 1 0.00 0.35 0.13 89.08
38 INT250912 Thbs2 Regulation of Thbs2 Regulation of Col7a1 1 0.03 0.35 0.13 89.08
39 INT250907 Thbs2 Regulation of Col7a1 1 0.03 0.35 0.13 89.08
40 INT152747 Negative_regulation of Abmm Positive_regulation of Tnf 1 0.01 0.64 0.2 88.08
41 INT152746 Abmm Positive_regulation of Tnf 1 0.01 0.64 0.2 87.48
42 INT247080 Binding of CRH and CRHBP 1 0.11 0.2 0.03 87.28
43 INT247077 CRHBP Regulation of Binding of CRH and CRHBP 1 0.06 0.2 0.03 87.28
44 INT247085 Binding of CRHBP and GHRH 1 0.01 0.2 0.03 87.28
45 INT278223 Binding of NOS3 and ACSM3 1 0.41 6.32 1.65 86.72
46 INT344891 Lhb Positive_regulation of Gene_expression of Ptger2 1 0.19 0.09 0 86.72
47 INT250016 Binding of IGHE and Il13 1 0.01 4.59 0.97 86.56
48 INT250003 Binding of IGHE and IL13 1 0.03 1.16 0.18 86.56
49 INT278224 Binding of ACSM3 and SNRNP70 1 0.04 3.76 1.01 86.24
50 INT240131 Binding of Crp and Nppb 7 0.07 11.53 2.12 86.12
51 INT271344 MPO Regulation of Protein_catabolism of ACCS 1 0.02 2.42 0.51 85.60
52 INT139538 Binding of CD34 and KIT 2 0.39 2.73 0.14 85.60
53 INT220188 EC Positive_regulation of CADM1 1 0.00 1.72 0.44 85.52
54 INT248344 Binding of IL10 and SNRNP70 1 0.04 0.6 0.05 85.44
55 INT101318 Negative_regulation of Binding of tf and Selp 1 0.01 0.77 0.17 83.04
56 INT101316 Binding of tf and Selp 1 0.01 0.77 0.17 83.04
57 INT229928 Binding of C3 and CFH 1 0.07 1.35 0.17 82.48
58 INT229931 Negative_regulation of Binding of C3 and CFH 1 0.08 1.35 0.17 82.48
59 INT141623 OLR1 Positive_regulation of Gene_expression of TF 1 0.01 1.39 0.21 81.72
60 INT141625 Crp Positive_regulation of Gene_expression of TF 1 0.11 1.39 0.21 81.72
61 INT345157 Lpar1 Positive_regulation of Gene_expression of Gtf3a 1 0.00 0.89 0.15 81.72
62 INT277065 CRP Positive_regulation of Gene_expression of MMP1 1 0.41 1.52 0.47 81.36
63 INT277064 CRP Positive_regulation of Gene_expression of TIMP1 1 0.15 1.47 0.45 81.36
64 INT277066 MMP1 Positive_regulation of Gene_expression of TIMP1 1 0.16 0.76 0.24 81.20
65 INT221256 Negative_regulation of CYC1 Positive_regulation of Gene_expression of Ros1 1 0.07 0.96 0 80.52
66 INT232592 Binding of Csf2 and Gtf3a 1 0.02 0.47 0.14 80.24
67 INT250911 Thbs2 Regulation of Mmp2 1 0.05 0.3 0.13 78.44
68 INT250910 Thbs2 Regulation of Tgm2 1 0.04 0.3 0.13 78.44
69 INT284450 Edn1 Positive_regulation of Gene_expression of MMP9 1 0.01 0.3 0.18 78.08
70 INT113780 AGT Positive_regulation of Positive_regulation of Nfkb1 1 0.00 1.25 0.64 77.92
71 INT101317 Binding of Selplg and Selp 1 0.02 3.72 1.01 77.04
72 INT277063 CRP Positive_regulation of Gene_expression of MMP10 1 0.39 1.53 0.48 76.92
73 INT287088 Binding of EEC1 and Vamp3 1 0.09 1.02 0 76.56
74 INT132115 Binding of Crp and Nfkb1 1 0.06 1.04 0.3 75.88
75 INT229982 Binding of C3 and amd 1 0.02 1.14 0.06 74.72
76 INT277011 CRP Positive_regulation of Gene_expression of F3 1 0.06 1.03 0.32 74.64
77 INT95644 PROC Negative_regulation of NPEPPS 1 0.00 1.24 0.35 73.84
78 INT278410 Gopc Positive_regulation of Phosphorylation of Syk 1 0.10 0.23 0 73.68
79 INT344723 Niacr1 Positive_regulation of Binding of APOB 1 0.31 1.05 0 73.24
80 INT278370 Gopc Positive_regulation of Positive_regulation of Msu 1 0.10 0.22 0 72.64
81 INT278386 Hps5 Positive_regulation of Positive_regulation of Msu 1 0.18 0.22 0 72.64
82 INT239783 Kcnip4 Positive_regulation of Gene_expression of Prh1 1 0.03 0.6 0.29 72.20
83 INT327875 Binding of Col7a1 and Postn 1 0.02 0.58 0.04 71.92
84 INT167523 Binding of Pepd and Aaas 1 0.02 0.5 0.15 71.12
85 INT349105 Hyal1 Positive_regulation of Gene_expression of Il6 1 0.30 0.25 0 71.00
86 INT277013 PLAT Positive_regulation of Gene_expression of F13A1 1 0.02 0.31 0.17 69.52
87 INT250015 Binding of FLNA and Nos3 1 0.05 1.09 0.06 69.52
88 INT344720 Niacr1 Negative_regulation of Binding of Hdl1 1 0.17 1.13 0 69.08
89 INT344396 Ucp2 Regulation of Ros1 1 0.04 1.31 0.31 68.88
90 INT251162 Clu Positive_regulation of Gene_expression of Trpv1 1 0.20 0.07 0.18 68.64
91 INT273892 LPA Positive_regulation of ALB 1 0.01 0.95 0.1 68.64
92 INT278374 Msu Positive_regulation of Phosphorylation of Gopc 1 0.14 0.21 0 68.60
93 INT278396 Msu Positive_regulation of Phosphorylation of Syk 1 0.25 0.27 0 68.60
94 INT127663 IRF6 Positive_regulation of PDE4A 1 0.14 0.76 0.48 68.40
95 INT252602 Binding of Cxcl10 and Ppig 1 0.08 1.55 0.96 67.32
96 INT120896 Binding of CCL2 and Il6 1 0.08 1.2 0.26 64.44
97 INT152748 Negative_regulation of Cpox Negative_regulation of Localization of Tnf 1 0.17 0.98 0.21 63.48
98 INT242878 INS Negative_regulation of Gene_expression of SPI1 1 0.04 1.81 0.27 63.28
99 INT278384 Il1 Negative_regulation of Ctsb 1 0.01 0.12 0 62.48
100 INT278375 Il1 Negative_regulation of Ctsr 1 0.01 0.12 0 62.48
101 INT260896 CRH Positive_regulation of Localization of MMP9 1 0.15 0.15 0.3 62.36
102 INT268459 Binding of LDLR and Olr1 1 0.00 0.78 0 61.92
103 INT22674 Binding of SERPINE1 and PLAT 7 0.04 0.65 0.45 61.68
104 INT302469 F2 Positive_regulation of Gene_expression of MMP9 1 0.01 1.82 0.62 60.72
105 INT302468 INCENP Positive_regulation of Gene_expression of MMP9 1 0.01 0.72 0.26 60.72
106 INT260807 Binding of Chkb and Tnfsf10 1 0.14 0.85 0 60.16
107 INT277072 Binding of PLA2G7 and Lipg 1 0.00 1.32 0.21 59.24
108 INT329589 Serpina5 Positive_regulation of PTX3 1 0.03 1.52 0.66 58.08
109 INT271345 Negative_regulation of PIGF Negative_regulation of FLT1 1 0.02 1.17 0.13 58.04
110 INT191493 Binding of AGTR1 and NLRP3 2 0.03 2.35 0.39 57.40
111 INT101943 Binding of CD40LG and HSD11B1 1 0.08 0.23 0 56.52
112 INT83446 CD40LG Positive_regulation of Localization of CCL2 1 0.00 0.17 0 56.36
113 INT285750 IL1B Positive_regulation of Localization of PRL 1 0.05 1.51 0.39 56.00
114 INT285744 IL1B Regulation of Localization of PRL 1 0.05 1.51 0.39 56.00
115 INT221232 Ptpn2 Positive_regulation of Gene_expression of Ros1 1 0.04 1.12 0.07 56.00
116 INT251170 Clu Positive_regulation of Trpv1 1 0.28 2.61 6.49 55.92
117 INT353912 Binding of ACLY and LARS 1 0.25 0.28 0.06 55.80
118 INT285746 IL6 Regulation of Localization of PRL 1 0.08 1.51 0.39 55.76
119 INT285749 IL6 Positive_regulation of Localization of PRL 1 0.08 1.51 0.39 55.76
120 INT213071 IL6 Positive_regulation of Gene_expression of CRP 4 0.52 6.58 1.68 55.64
121 INT221252 Akt1 Negative_regulation of Localization of CYC1 1 0.15 0.9 0 54.44
122 INT247082 Binding of PLAT and PTBP1 1 0.14 0.59 0.18 51.44
123 INT221240 Akt1 Positive_regulation of Phosphorylation of Bcl2 1 0.00 0.89 0 50.64
124 INT106464 STK16 Positive_regulation of Gene_expression of MMP1 2 0.06 0.05 0 50.08
125 INT324897 Binding of Ptbp1 and Il1 1 0.01 0.62 0.3 49.64
126 INT260894 CRH Regulation of Localization of MMP3 1 0.21 0.36 0.85 48.80
127 INT265342 sb Negative_regulation of Bcl2l1 1 0.00 0.65 0 48.56
128 INT277012 Binding of PAPPA and ACE2 1 0.02 1.26 0.15 47.64
129 INT277990 Binding of Cd3e and Hand1 1 0.01 0.5 0.16 46.36
130 INT252426 Binding of SLURP1 and Negative_regulation of Gene_expression of TNF 1 0.01 1.13 0.49 43.80
131 INT302466 Positive_regulation of F2 Positive_regulation of Gene_expression of MMP9 1 0.01 1.1 0.35 42.40
132 INT276497 F3 Positive_regulation of F7 1 0.02 1.64 0.1 41.44
133 INT276495 TF Positive_regulation of F7 1 0.23 1.63 0.1 41.44
134 INT191501 NLRP3 Positive_regulation of ECE1 1 0.01 1.09 0.28 41.08
135 INT191505 NLRP3 Positive_regulation of Protein_catabolism of EDN1 1 0.00 1.1 0.28 41.08
136 INT191495 NLRP3 Positive_regulation of Protein_catabolism of ECE1 1 0.01 1.09 0.28 41.08
137 INT327871 Binding of Notch1 and Postn 1 0.38 1.42 0.07 40.68
138 INT327878 Binding of Egf and Postn 1 0.18 0.37 0 40.68
139 INT285406 ELF3 Positive_regulation of Binding of ROS1 1 0.08 0.9 0.03 40.56
140 INT285407 ELF3 Regulation of ICAM1 1 0.03 0.91 0.03 40.56
141 INT345059 Binding of C3 and C2 1 0.00 0 0 38.00
142 INT224410 Binding of CRP and CIMT 3 0.42 10.46 1.2 36.56
143 INT310186 Binding of Gdf2 and Bmpr2 1 0.02 0 0 36.52
144 INT310189 Binding of Acvrl1 and Gdf2 1 0.01 0 0 36.52
145 INT254860 Ctgf Negative_regulation of Col7a1 1 0.00 0.51 0.03 34.16
146 INT286349 IRF6 Positive_regulation of Localization of IL10 1 0.03 1.22 0.55 34.08
147 INT188164 Binding of ALPP and HIVEP1 1 0.02 1.15 0 33.08
148 INT254867 Ctgf Negative_regulation of Serpine1 1 0.04 0.51 0.03 33.04
149 INT242036 CRP Regulation of CHDH 1 0.18 1.57 0 31.68
150 INT209859 IL4 Positive_regulation of PPARA 1 0.22 1.66 0.69 30.04
151 INT209854 IL4 Positive_regulation of Gene_expression of CD36 1 0.51 1.2 0.65 30.04
152 INT209847 IL4 Positive_regulation of PPARA Positive_regulation of Gene_expression of CD36 1 0.22 0.83 0.34 30.04
153 INT199312 Edn1 Negative_regulation of VEGFA 1 0.01 0.76 0 29.40
154 INT230752 Gene_expression of Agtr2 Positive_regulation of Gene_expression of Mcpt1 1 0.01 1.34 0.3 28.72
155 INT251164 Binding of Clu and Trpv1 1 0.19 0.44 2.23 28.64
156 INT271354 MPO Regulation of Gene_expression of CRP 1 0.16 1.74 0.08 28.04
157 INT271351 MPO Positive_regulation of CRP 1 0.07 1.69 0.08 28.04
158 INT277010 Binding of PAPPA and TNNT1 1 0.24 0.99 0.07 27.44
159 INT277016 Binding of MB and PAPPA 1 0.10 1 0.07 27.44
160 INT271348 Binding of CHKB and MB 1 0.01 1.01 0 26.32
161 INT310187 Acvrl1 Regulation of Gene_expression of Bmpr2 1 0.04 0 0 25.72
162 INT142075 IL4 Negative_regulation of Binding of IDO1 1 0.02 2.07 1.19 25.00
163 INT142077 TGFB1 Negative_regulation of Binding of IDO1 1 0.15 2.07 1.19 25.00
164 INT278378 Hps5 Positive_regulation of Gene_expression of S100a8 1 0.00 0.42 0.09 25.00
165 INT278371 Binding of Il1 and Hps5 1 0.02 0.44 0.09 25.00
166 INT278368 Regulation of Binding of Il1 and Hps5 1 0.02 0.44 0.09 25.00
167 INT329371 IL8 Negative_regulation of Jun 1 0.00 0.95 0.13 23.96
168 INT329368 Ccl2 Negative_regulation of Jun 1 0.01 1.87 0.24 23.60
169 INT342456 AGT Positive_regulation of Gene_expression of CCL2 1 0.07 0.63 0.25 23.00
170 INT175911 Binding of SERPINE1 and CNBP 1 0.01 1.02 0.22 21.60
171 INT230750 Crp Positive_regulation of Edn1 1 0.10 0.27 0.09 21.08
172 INT230746 Crp Positive_regulation of Localization of Serpine1 1 0.16 0.27 0.09 21.08
173 INT186240 Binding of AGRP and SCN5A 2 0.13 1.19 0.1 20.80
174 INT338059 Nrtn Positive_regulation of Gene_expression of F2r 1 0.12 0.45 0.41 20.56
175 INT99015 Binding of Selp and Vcam1 2 0.27 1.76 0.35 19.88
176 INT175910 SERPINE1 Negative_regulation of PLAU 1 0.06 1.01 0.22 19.64
177 INT175322 Oxt Positive_regulation of Gene_expression of PTGER2 1 0.00 0.09 0.25 18.60
178 INT330530 Binding of PON1 and CIMT 1 0.14 1.48 0 18.12
179 INT209855 NFE2L2 Positive_regulation of Gene_expression of CD36 1 0.27 0.72 0.32 17.00
180 INT106744 Binding of CRP and EGFL7 2 0.07 2.35 0.51 15.56
181 INT172833 Binding of FFAR1 and T2dm2 1 0.00 1.55 0 12.36
182 INT325901 Binding of Dio1 and F2 1 0.01 0.63 0 8.32
183 INT194863 Binding of IL1R1 and IL1RN 5 0.09 2.23 1.64 6.48
184 INT276668 Ngf Regulation of Nav1 1 0.09 0.98 1.85 6.00
185 INT266655 TIMP1 Regulation of Gene_expression of MMP9 1 0.18 0.11 0.06 5.32
186 INT266662 TIMP1 Regulation of Gene_expression of GOPC 1 0.06 0.11 0.06 5.32
187 INT149117 Binding of CD80 and CTLA4 31 0.52 12.7 7.73 5.00
188 INT155484 Binding of CD86 and CTLA4 15 0.52 8.85 6.09 5.00
189 INT182124 Binding of IRF6 and TLR4 14 0.10 16.11 4.65 5.00
190 INT101942 Binding of CD40 and CD40LG 16 0.23 15.24 4.01 5.00
191 INT349583 Aap Positive_regulation of Gene_expression of Cyp2e1 1 0.18 1.57 3.59 5.00
192 INT180984 IRF6 Positive_regulation of Localization of IL8 7 0.11 2.13 3.47 5.00
193 INT276678 Nkx1-1 Regulation of Nav1 1 0.15 0.88 3.31 5.00
194 INT276676 Prkcg Regulation of Nav1 1 0.30 0.82 3.29 5.00
195 INT349584 Binding of Cyp2e1 and Aap 1 0.10 1.56 3.24 5.00
196 INT64719 IL1B Positive_regulation of IL6 7 0.41 6.84 3.14 5.00
197 INT276679 Prkcg Positive_regulation of Positive_regulation of Nkx1-1 1 0.07 0.94 3.08 5.00
198 INT130721 Binding of IL1B and IL1RN 6 0.05 5.29 2.85 5.00
199 INT349589 Aap Positive_regulation of Cyp2e1 1 0.21 1.84 2.71 5.00
200 INT115367 Binding of IL6 and IL6R 12 0.07 8.16 2.36 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Rupture. They are ordered first by their pain relevance and then by number of times they were reported in Rupture. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT16323 Gene_expression of pr 62 0.66 36.14 38.26 100.00
2 INT78024 Gene_expression of ACLY 73 0.75 59.15 18.54 100.00
3 INT32420 Binding of Cir1 1 0.47 1.33 0.06 100.00
4 INT39406 Positive_regulation of OLR1 45 0.70 37.8 7.72 100.00
5 INT32419 Negative_regulation of Cir1 2 0.43 1.37 0.5 100.00
6 INT15502 Regulation of asp1 6 0.19 2.29 1.2 100.00
7 INT3117 Regulation of Oxt 103 0.61 17.93 32.28 100.00
8 INT9852 Positive_regulation of Gpt 563 0.70 364.64 146.82 100.00
9 INT21650 Regulation of OXTR 29 0.61 5.99 4.91 100.00
10 INT121788 Localization of BCS1L 11 0.73 10.16 1.14 100.00
11 INT42032 Localization of PNLIP 4 0.14 3.44 0.41 100.00
12 INT77853 Positive_regulation of Gene_expression of tf 20 0.31 22.75 5.94 99.98
13 INT92129 Positive_regulation of Gene_expression of F3 13 0.08 12.13 2.02 99.98
14 INT9408 Positive_regulation of Crp 296 0.69 242.27 57.35 99.92
15 INT48232 Gene_expression of MMP1 245 0.78 96.31 57.72 99.92
16 INT8539 Negative_regulation of Serpina1a 21 0.58 12.65 3.39 99.90
17 INT190781 Binding of Acsl1 6 0.36 9.12 0.76 99.90
18 INT173592 Binding of COL5A2 32 0.33 9.14 2.48 99.84
19 INT184532 Binding of SMUG1 7 0.21 5.73 1.45 99.82
20 INT9549 Regulation of CHKB 25 0.47 13.61 3.2 99.82
21 INT9552 Positive_regulation of TNNI3 209 0.70 128.67 19.15 99.78
22 INT39564 Negative_regulation of Gene_expression of Ptger2 50 0.42 30.9 12.97 99.76
23 INT78182 Positive_regulation of ACCS 43 0.43 46.39 6.78 99.68
24 INT219618 Regulation of Gene_expression of Tpe1 1 0.02 1.21 0.17 99.68
25 INT22909 Positive_regulation of Chdh 26 0.68 28.69 16.13 99.68
26 INT50105 Localization of CTSB 29 0.78 10.98 5.21 99.68
27 INT173639 Positive_regulation of INCENP 40 0.14 20.97 6.7 99.66
28 INT79115 Binding of Tap1 12 0.47 4.21 0.95 99.62
29 INT158124 Gene_expression of COL5A2 136 0.69 72.3 12.44 99.56
30 INT63506 Localization of F2 21 0.77 7.53 3.41 99.56
31 INT22558 Gene_expression of COL3A1 10 0.78 7.22 1.36 99.56
32 INT22556 Positive_regulation of Gene_expression of COL3A1 5 0.37 4.25 0.64 99.56
33 INT67822 Binding of SERPINH1 17 0.36 19.05 7.24 99.54
34 INT219617 Negative_regulation of Positive_regulation of Tap1 1 0.27 1.03 0.07 99.54
35 INT211807 Binding of PTBP1 11 0.31 6.09 0.45 99.54
36 INT99608 Transcription of MMP9 18 0.65 9.67 4.11 99.52
37 INT4398 Regulation of LGALS1 7 0.44 2.16 2.31 99.50
38 INT38482 Gene_expression of Aspn 2 0.04 1.45 0.12 99.50
39 INT16772 Gene_expression of MPO 81 0.78 90.98 11.9 99.48
40 INT36287 Binding of CD4 96 0.47 58.93 11.88 99.44
41 INT90654 Binding of Hpt 2 0.40 2.37 0.38 99.44
42 INT899 Gene_expression of F13A1 122 0.70 78.02 16.26 99.42
43 INT18007 Positive_regulation of C6orf25 23 0.66 14.98 1.95 99.42
44 INT247970 Regulation of CLTC 8 0.28 5.37 1.06 99.40
45 INT78895 Regulation of CCL5 30 0.46 20.45 10.18 99.40
46 INT98251 Binding of IL12A 20 0.37 16.03 4.51 99.40
47 INT140449 Positive_regulation of Tap1 5 0.68 1.84 0.74 99.38
48 INT188241 Negative_regulation of ADIPOQ 16 0.43 22.16 1.47 99.36
49 INT1888 Protein_catabolism of F13A1 97 0.99 63.48 14.82 99.36
50 INT278927 Localization of Meta 3 0.78 1.66 0.71 99.34
51 INT7533 Gene_expression of Tlr4 720 0.78 343.22 121.57 99.32
52 INT258548 Positive_regulation of Meta 10 0.67 5.05 1.42 99.32
53 INT216978 Binding of Pycard 6 0.25 2.93 0.22 99.30
54 INT38481 Gene_expression of D9Ucl1e 2 0.10 1.11 0.07 99.30
55 INT39565 Gene_expression of Ptger2 424 0.75 229.28 72.68 99.28
56 INT193015 Positive_regulation of Gene_expression of EPAS1 6 0.32 8.77 0.21 99.28
57 INT591 Negative_regulation of Serpinc1 44 0.57 31.73 8.82 99.28
58 INT1759 Gene_expression of TIMP1 267 0.77 133.87 59.29 99.26
59 INT278321 Localization of Ctsb 1 0.14 0.67 0.03 99.24
60 INT54571 Positive_regulation of NFKB1 263 0.70 138.99 87.32 99.22
61 INT187133 Protein_catabolism of TIMP1 19 0.73 11.3 5.51 99.20
62 INT171820 Localization of Fig4 144 0.65 27.38 20.88 99.20
63 INT187505 Positive_regulation of Localization of Fig4 16 0.24 1.21 3.17 99.20
64 INT219619 Gene_expression of Tpe1 1 0.03 1.2 0.17 99.18
65 INT17612 Gene_expression of CRP 676 0.78 580.61 119.03 99.12
66 INT173587 Protein_catabolism of COL5A2 59 0.32 32.73 8.96 99.12
67 INT11313 Positive_regulation of Il6 526 0.70 331.27 201.59 99.12
68 INT137454 Gene_expression of ADIPOQ 88 0.78 85.32 6.2 99.12
69 INT36449 Negative_regulation of G6PD 74 0.59 54.15 8.85 99.12
70 INT50932 Positive_regulation of Positive_regulation of Il6 36 0.69 24.9 16.12 99.12
71 INT18523 Negative_regulation of ALOX15 15 0.59 14.2 5.92 99.12
72 INT1579 Gene_expression of PRL 279 0.78 119.2 55.41 99.12
73 INT14737 Gene_expression of FN1 117 0.78 78.74 18.99 99.12
74 INT89661 Gene_expression of Hrec 102 0.21 69.91 39.57 99.08
75 INT82845 Binding of F10 25 0.37 7.07 0.81 99.06
76 INT142594 Gene_expression of Tlr2 165 0.78 139.73 22.26 99.04
77 INT45342 Binding of AVSD1 6 0.31 7.23 0.27 99.04
78 INT860 Regulation of ALB 48 0.60 25.11 8.95 99.04
79 INT172109 Gene_expression of SLC26A3 4 0.53 2.28 0.23 99.04
80 INT21582 Regulation of Gene_expression of TIMP1 20 0.61 12.39 4.77 99.02
81 INT38268 Positive_regulation of BEST1 16 0.17 14.54 1.93 99.02
82 INT339265 Negative_regulation of Gene_expression of EPAS1 2 0.15 2.67 0 99.02
83 INT51055 Positive_regulation of TIMP1 103 0.69 50.07 19.86 99.00
84 INT209912 Gene_expression of Pycard 17 0.22 12.04 1.04 98.98
85 INT16722 Negative_regulation of MPO 25 0.59 18.55 6.99 98.96
86 INT75869 Gene_expression of Acsl1 24 0.45 27.76 3.66 98.92
87 INT183672 Gene_expression of EPAS1 37 0.35 28.68 0.72 98.86
88 INT11679 Negative_regulation of F13A1 55 0.54 33.69 9.43 98.76
89 INT152745 Positive_regulation of Bid 2 0.32 2.67 0.23 98.76
90 INT937 Positive_regulation of Oxt 195 0.70 37.82 49.3 98.74
91 INT46088 Localization of F3 15 0.37 13.7 2.23 98.74
92 INT93533 Positive_regulation of Tnfsf11 53 0.50 36.93 10.53 98.72
93 INT23224 Gene_expression of tf 99 0.56 60.22 22.03 98.72
94 INT18677 Gene_expression of F3 50 0.65 30.86 5.86 98.72
95 INT85971 Positive_regulation of Gene_expression of Cd40lg 14 0.66 7.61 3.29 98.72
96 INT39050 Positive_regulation of PGF 14 0.49 8.05 1.43 98.72
97 INT157666 Positive_regulation of GOPC 335 0.60 120.19 42.75 98.70
98 INT48406 Gene_expression of Icam1 277 0.78 238.28 81.71 98.68
99 INT89282 Regulation of MMP9 39 0.60 25.45 10.34 98.68
100 INT37390 Regulation of Crp 39 0.46 28.74 11.45 98.68
101 INT49105 Gene_expression of Vcam1 157 0.78 157.27 43.01 98.68
102 INT81399 Regulation of Vcam1 24 0.46 23.53 7.68 98.68
103 INT62944 Regulation of Icam1 33 0.47 23.52 7.94 98.68
104 INT297020 Positive_regulation of CLTC 5 0.36 3.38 0.41 98.66
105 INT32074 Positive_regulation of TAR 4 0.40 1.44 0.98 98.64
106 INT187731 Negative_regulation of Gene_expression of DBT 1 0.09 0.3 0.03 98.64
107 INT302888 Positive_regulation of HIST1H4PS1 3 0.05 1.52 0.32 98.62
108 INT55737 Positive_regulation of MMP2 101 0.68 59.11 27.71 98.60
109 INT198101 Negative_regulation of AVSD1 2 0.19 0.89 0.08 98.60
110 INT171686 Binding of asp1 8 0.31 11.88 1.07 98.56
111 INT64777 Negative_regulation of COL5A2 32 0.38 17.4 2.28 98.56
112 INT2431 Positive_regulation of Mpo 275 0.70 211.99 78.47 98.52
113 INT128305 Positive_regulation of Cx3cr1 4 0.60 2.29 3.04 98.52
114 INT15516 Gene_expression of Crp 711 0.77 615.33 173.09 98.48
115 INT168381 Positive_regulation of Mmp3 24 0.58 19.12 7.03 98.48
116 INT76915 Localization of Gpx3 6 0.14 4.48 0.89 98.48
117 INT81229 Binding of COL1A1 24 0.35 12.07 3.3 98.46
118 INT82871 Protein_catabolism of MMP1 13 0.96 10.71 4.09 98.44
119 INT85966 Gene_expression of Cd40lg 50 0.73 30.9 9.11 98.44
120 INT127669 Regulation of Negative_regulation of PDE4A 4 0.45 2.74 0.88 98.44
121 INT278331 Localization of Hps5 3 0.34 4.14 0.34 98.44
122 INT38556 Gene_expression of DBT 47 0.50 12.52 5.6 98.42
123 INT28872 Positive_regulation of CSRP1 49 0.70 47.23 11.7 98.40
124 INT6580 Negative_regulation of Ptgs1 929 0.59 381.53 376.26 98.40
125 INT54438 Binding of ALPP 25 0.39 14.02 0.96 98.40
126 INT1951 Positive_regulation of Tlr4 345 0.70 176.99 62.42 98.36
127 INT102680 Protein_catabolism of COL7A1 49 0.69 34.68 15.78 98.36
128 INT71601 Positive_regulation of ACD 11 0.60 6.55 0.9 98.34
129 INT48555 Binding of SP1 30 0.46 11.38 6.53 98.32
130 INT67346 Regulation of Gene_expression of F3 2 0.13 1.42 0.6 98.32
131 INT1950 Positive_regulation of Positive_regulation of Tlr4 38 0.49 20.17 7.14 98.32
132 INT13240 Gene_expression of TF 94 0.76 57.81 10.99 98.28
133 INT50569 Gene_expression of HCA1 10 0.59 3.76 0.89 98.28
134 INT53235 Regulation of Il1f5 3 0.19 2.45 1.01 98.28
135 INT52358 Gene_expression of Cx3cr1 25 0.78 18.48 16.65 98.28
136 INT143158 Negative_regulation of Gene_expression of TLR4 31 0.56 20.62 5.69 98.28
137 INT927 Gene_expression of Oxt 184 0.78 44.71 35.79 98.28
138 INT48970 Positive_regulation of LILRB1 7 0.67 11.38 0.67 98.24
139 INT86521 Gene_expression of Lpar1 167 0.78 154.61 80.35 98.24
140 INT189092 Gene_expression of Tap1 56 0.76 14.09 1.33 98.22
141 INT219620 Gene_expression of F11R 3 0.65 2.8 0.14 98.22
142 INT103245 Positive_regulation of Gene_expression of MMP9 64 0.68 36.86 15.7 98.16
143 INT55669 Negative_regulation of Gene_expression of Ik 14 0.13 11.28 5 98.16
144 INT10101 Binding of PLAT 24 0.36 12.62 2.78 98.08
145 INT91511 Positive_regulation of Localization of CYC1 15 0.67 14.68 3.57 98.08
146 INT55740 Gene_expression of Timp1 53 0.75 28.63 13.85 98.08
147 INT39948 Binding of FLNA 45 0.42 58.05 4.27 98.04
148 INT197102 Localization of FLT4 4 0.65 2.89 0.17 98.04
149 INT117223 Gene_expression of TLR4 348 0.78 206.18 54.42 98.00
150 INT55671 Gene_expression of Ik 151 0.27 80.1 48.49 98.00
151 INT261192 Gene_expression of Niacr1 57 0.67 24.37 1.89 98.00
152 INT94438 Gene_expression of OLR1 86 0.78 80.38 11.03 97.96
153 INT99610 Localization of MMP9 126 0.79 48.46 32.67 97.96
154 INT126164 Positive_regulation of Ctsb 15 0.49 3.34 0.63 97.96
155 INT8798 Positive_regulation of Csrp1 61 0.69 63.86 14.14 97.96
156 INT24983 Binding of MPO 18 0.42 17.56 3.29 97.96
157 INT238903 Negative_regulation of Gene_expression of OLR1 4 0.41 3.18 0.77 97.96
158 INT53475 Gene_expression of MRI1 116 0.59 77.68 33.98 97.88
159 INT90202 Protein_catabolism of MMP2 15 0.94 7.47 5.41 97.88
160 INT342465 Protein_catabolism of MRI1 1 0.04 0.79 0.38 97.88
161 INT110110 Gene_expression of ACCS 85 0.58 75.88 10.2 97.84
162 INT7035 Regulation of CGA 87 0.45 29.04 28.45 97.84
163 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74 97.80
164 INT214456 Gene_expression of SMAP2 1 0.06 1.09 0.05 97.80
165 INT73048 Gene_expression of MMP9 268 0.77 159.75 57.81 97.76
166 INT16428 Positive_regulation of Gtf3a 135 0.20 106.44 26.67 97.76
167 INT87420 Gene_expression of BCL2L1 56 0.75 48.84 5.32 97.76
168 INT180163 Positive_regulation of Nfasc 49 0.40 31.96 9.41 97.76
169 INT144053 Transcription of GATA3 1 0.67 0.89 0.54 97.76
170 INT143952 Regulation of Gene_expression of MMP9 14 0.53 10.16 2.73 97.76
171 INT647 Gene_expression of SGCG 211 0.75 78.46 55.82 97.72
172 INT91509 Localization of CYC1 39 0.78 34.74 7.17 97.72
173 INT271362 Positive_regulation of PIGF 1 0.19 4.16 0.54 97.72
174 INT242267 Localization of Slc25a16 1 0.34 6.15 0.43 97.64
175 INT74977 Binding of FGFR1 6 0.41 4.66 1.02 97.64
176 INT65261 Regulation of Col7a1 18 0.55 8.7 1.33 97.62
177 INT187994 Binding of CIMT 20 0.47 12.97 2.04 97.60
178 INT44003 Gene_expression of F3 40 0.75 27.92 8.29 97.56
179 INT73047 Positive_regulation of MMP9 133 0.68 73.22 26.42 97.52
180 INT165100 Positive_regulation of Cx3cl1 1 0.21 0.38 0.19 97.52
181 INT20102 Gene_expression of Serpine1 102 0.78 65.99 12.61 97.44
182 INT4953 Positive_regulation of CGB5 16 0.60 7.63 2.49 97.40
183 INT16184 Negative_regulation of CHKB 20 0.53 10.61 1.42 97.40
184 INT216098 Positive_regulation of Imraq1 1 0.06 0.49 0 97.40
185 INT172678 Gene_expression of NUPL2 20 0.75 5.06 2.85 97.32
186 INT81628 Positive_regulation of Gene_expression of Fas 32 0.67 38.13 4.23 97.32
187 INT165490 Regulation of Lpar1 8 0.45 15.31 5.05 97.32
188 INT24816 Binding of CD40LG 68 0.47 45.48 11.56 97.28
189 INT119830 Gene_expression of BAD 24 0.50 20.05 1.41 97.28
190 INT3104 Negative_regulation of CGA 76 0.54 29.81 12.23 97.24
191 INT157802 Negative_regulation of Timp2 7 0.54 5.75 5.51 97.24
192 INT2604 Positive_regulation of Got1 223 0.70 154.78 49.51 97.24
193 INT22429 Positive_regulation of PDAP1 34 0.61 22.58 2.91 97.24
194 INT324890 Negative_regulation of Negative_regulation of Timp2 2 0.40 1.09 0.68 97.24
195 INT220858 Positive_regulation of Mmp1a 15 0.38 9.11 2.77 97.20
196 INT81289 Positive_regulation of Gene_expression of Tlr4 192 0.69 104.5 33.89 97.20
197 INT14598 Gene_expression of Tpsab1 40 0.73 14.55 5.4 97.20
198 INT181271 Regulation of Localization of GPSM2 1 0.21 0.19 0 97.20
199 INT77670 Positive_regulation of ACLY 24 0.49 21.68 3.12 97.12
200 INT97674 Positive_regulation of Localization of Calca 70 0.69 27.71 51.79 97.10
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