D:Scheuermann's Disease

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Disease Term
Synonyms Disease Scheuermann, Disease Scheuermann S, Scheuermann Disease, Scheuermann S Disease, Scheuermanns Disease
Documents 16
Hot Single Events 4
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Scheuermann's Disease. They are ordered first by their relevance to Scheuermann's Disease and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT245731 Binding of COL5A2 and DISC1 1 0.01 0.42 0 18.44
2 INT245732 Binding of COL9A2 and DISC1 1 0.07 1.34 0.08 5.00
3 INT245726 SOX9 Regulation of SGCG 1 0.00 0.29 0 5.00
4 INT245727 Binding of SUGT1 and DISC1 1 0.00 1.57 0 5.00
5 INT245728 Binding of TRNAP2 and DISC1 1 0.03 0.54 0 5.00
6 INT245729 Binding of COL9A1 and COL9A3 1 0.29 0.52 0 5.00
7 INT245730 RENBP Regulation of DISC1 1 0.01 0.58 0 5.00
8 INT245733 Binding of VDR and DISC1 1 0.03 0.75 0 5.00
9 INT245734 Binding of COL9A1 and COL9A2 1 0.26 0.52 0 5.00
10 INT245735 SOX9 Regulation of COL5A2 1 0.07 0.29 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Scheuermann's Disease. They are ordered first by their pain relevance and then by number of times they were reported in Scheuermann's Disease. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT245744 Protein_catabolism of DISC1 1 0.18 4.92 0.21 94.96
2 INT245737 Positive_regulation of Protein_catabolism of DISC1 1 0.09 1.04 0.06 94.96
3 INT245747 Positive_regulation of Binding of COL9A3 1 0.42 1.05 0.06 93.80
4 INT245740 Binding of COL9A3 2 0.31 1.85 0.08 93.24
5 INT173592 Binding of COL5A2 32 0.33 9.14 2.48 76.08
6 INT101177 Regulation of COL5A2 12 0.45 4.03 0.62 61.52
7 INT245761 Positive_regulation of Regulation of COL5A2 1 0.06 0.76 0 61.52
8 INT245762 Transcription of COL5A2 4 0.09 2.82 0 61.52
9 INT73297 Positive_regulation of Transcription of Col1a1 2 0.32 3.12 0.14 60.32
10 INT8890 Transcription of Col1a1 10 0.63 4.02 2.48 59.60
11 INT67719 Positive_regulation of Col1a1 21 0.44 8.87 3.12 59.60
12 INT120860 Positive_regulation of Gene_expression of Col1a1 12 0.44 4.84 1.34 58.28
13 INT245725 Positive_regulation of Negative_regulation of Col1a1 1 0.21 0.7 0 58.28
14 INT69215 Gene_expression of Col1a1 38 0.68 17.39 4.77 57.92
15 INT153201 Negative_regulation of Gene_expression of Col1a1 7 0.38 6.37 1.52 57.92
16 INT59473 Negative_regulation of Col1a1 4 0.25 1.33 1.24 57.92
17 INT245753 Regulation of Transcription of COL5A2 1 0.08 0.64 0 49.24
18 INT64777 Negative_regulation of COL5A2 32 0.38 17.4 2.28 44.36
19 INT158124 Gene_expression of COL5A2 136 0.69 72.3 12.44 27.96
20 INT245736 Gene_expression of DISC1 13 0.61 7.65 1.33 27.60
21 INT647 Gene_expression of SGCG 211 0.75 78.46 55.82 18.08
22 INT67890 Positive_regulation of Gene_expression of SGCG 26 0.67 9.91 6.41 18.08
23 INT179644 Gene_expression of RENBP 26 0.35 13.74 1.38 17.64
24 INT211363 Positive_regulation of RENBP 13 0.22 13.26 6.48 16.08
25 INT245748 Binding of DISC1 1 0.07 5.21 1.08 10.84
26 INT245765 Binding of SOX9 1 0.31 0.87 0 5.56
27 INT822 Gene_expression of ESR1 529 0.78 302.16 63.64 5.00
28 INT29496 Gene_expression of MMP3 136 0.75 49.49 41.78 5.00
29 INT84825 Gene_expression of CD36 121 0.78 43.73 33.23 5.00
30 INT15610 Localization of GOPC 223 0.65 68.26 28.7 5.00
31 INT27933 Gene_expression of NCOR2 65 0.72 31.35 24.23 5.00
32 INT11659 Gene_expression of COL2A1 164 0.78 78.49 22.58 5.00
33 INT119700 Gene_expression of VDR 88 0.75 65.33 11.5 5.00
34 INT49027 Gene_expression of TYRP1 35 0.75 9.81 6.06 5.00
35 INT68591 Regulation of TYRP1 14 0.44 3.93 5.05 5.00
36 INT20552 Negative_regulation of Gene_expression of COL2A1 29 0.56 11.92 4.81 5.00
37 INT102237 Positive_regulation of Gene_expression of MMP3 22 0.44 7.77 4.71 5.00
38 INT84911 Gene_expression of SUGT1 43 0.11 19.85 4.54 5.00
39 INT217742 Positive_regulation of Gene_expression of COL2A1 20 0.67 9.76 4.23 5.00
40 INT181922 Binding of RENBP 16 0.36 13.92 3.71 5.00
41 INT53021 Positive_regulation of COL2A1 29 0.55 27.75 3.47 5.00
42 INT102638 Regulation of VDR 21 0.44 9.92 2.54 5.00
43 INT102639 Positive_regulation of VDR 31 0.69 18.05 2.38 5.00
44 INT174541 Positive_regulation of Gene_expression of COL5A2 18 0.36 14.17 2.12 5.00
45 INT102989 Regulation of Gene_expression of MMP3 10 0.53 3.29 1.47 5.00
46 INT134663 Gene_expression of SOX9 40 0.75 9.07 1.2 5.00
47 INT11658 Regulation of Gene_expression of COL2A1 9 0.62 3.09 1.11 5.00
48 INT209948 Gene_expression of CLEC3B 3 0.78 11.51 0.6 5.00
49 INT184222 Negative_regulation of SOX9 7 0.41 2.68 0.58 5.00
50 INT211361 Regulation of RENBP 5 0.08 2.8 0.38 5.00
51 INT245764 Regulation of DISC1 1 0.08 1.23 0.38 5.00
52 INT245741 Negative_regulation of Gene_expression of DISC1 2 0.17 1.29 0.34 5.00
53 INT245763 Regulation of SOX9 4 0.43 1.68 0.21 5.00
54 INT134662 Positive_regulation of Gene_expression of SOX9 9 0.48 1.69 0.19 5.00
55 INT245756 Regulation of Binding of DISC1 1 0.08 0.63 0.16 5.00
56 INT184220 Negative_regulation of Gene_expression of SOX9 4 0.36 0.58 0.09 5.00
57 INT245743 Positive_regulation of Gene_expression of DISC1 1 0.09 0.72 0.07 5.00
58 INT245760 Regulation of Gene_expression of DISC1 1 0.08 0.72 0.07 5.00
59 INT245738 Positive_regulation of COL9A2 1 0.38 0.72 0.06 5.00
60 INT245750 Regulation of COL9A3 1 0.20 0.7 0.06 5.00
61 INT245754 Regulation of Positive_regulation of COL9A2 1 0.34 0.74 0.06 5.00
62 INT245742 Positive_regulation of DISC1 1 0.13 0.83 0.04 5.00
63 INT245746 Positive_regulation of Localization of DISC1 1 0.09 0.35 0.04 5.00
64 INT245751 Gene_expression of COL9A2 4 0.65 1.83 0.04 5.00
65 INT245759 Localization of DISC1 1 0.14 2.85 0.04 5.00
66 INT245739 Gene_expression of COL9A1 1 0.54 0.53 0 5.00
67 INT245745 Regulation of TRNAP2 1 0.16 0.45 0 5.00
68 INT245749 Gene_expression of TRNAP2 1 0.27 1.16 0 5.00
69 INT245752 Positive_regulation of Binding of SOX9 1 0.41 0.48 0 5.00
70 INT245755 Gene_expression of COL9A3 1 0.57 0.54 0 5.00
71 INT245757 Localization of SOX9 4 0.62 0.8 0 5.00
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