D:Schnitzler Syndrome

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pChart

Disease Term
Synonyms None
Documents 23
Hot Single Events 8
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Schnitzler Syndrome. They are ordered first by their relevance to Schnitzler Syndrome and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT317833 Nlrp3 Positive_regulation of Localization of Il1 1 0.06 1.38 0.26 55.80
2 INT317832 Binding of Mefv and Il1 1 0.03 3.89 0.7 9.92
3 INT317834 Binding of Pstpip1 and Il1 1 0.00 2.03 0.48 9.92
4 INT278379 Binding of Pstpip1 and Mefv 3 0.03 2.02 0.48 8.40
5 INT317836 Binding of Fibp and Pycard 1 0.00 2.68 0.98 5.00
6 INT317835 Nlrp3 Positive_regulation of Il18 1 0.08 1.49 0.31 5.00
7 INT317831 Binding of Mefv and Nlrx1 1 0.00 1.77 0.2 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Schnitzler Syndrome. They are ordered first by their pain relevance and then by number of times they were reported in Schnitzler Syndrome. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT569 Negative_regulation of C4a 13 0.42 9.48 2.85 98.24
2 INT11381 Positive_regulation of IL1B 330 0.70 209.31 100.9 94.04
3 INT19472 Gene_expression of Il1 554 0.76 419.75 175.35 90.24
4 INT78515 Negative_regulation of Mag 10 0.54 9.4 5.06 83.32
5 INT18010 Positive_regulation of CD40LG 122 0.70 100.8 18.46 81.60
6 INT85970 Positive_regulation of Cd40lg 21 0.53 8.51 3.16 81.60
7 INT100861 Binding of CRP 179 0.48 175.2 26.45 80.52
8 INT20462 Binding of ESR1 210 0.44 102.7 26.34 80.52
9 INT19430 Positive_regulation of IGHA1 10 0.67 6.42 2.58 77.08
10 INT25607 Binding of Il1 82 0.47 64.4 23.9 76.96
11 INT3361 Positive_regulation of Esr1 273 0.69 208.53 44.81 73.04
12 INT12265 Positive_regulation of IgG 168 0.63 104.89 19.76 66.52
13 INT4509 Gene_expression of IgG 426 0.76 293.69 56.64 61.12
14 INT219136 Positive_regulation of Positive_regulation of Nlrp3 3 0.49 2.61 0.58 61.00
15 INT17612 Gene_expression of CRP 676 0.78 580.61 119.03 59.76
16 INT822 Gene_expression of ESR1 529 0.78 302.16 63.64 59.76
17 INT6105 Positive_regulation of IL2 133 0.69 82.76 34.67 57.68
18 INT36221 Positive_regulation of Nlrp3 25 0.68 19.7 4.5 57.20
19 INT8243 Positive_regulation of Il6 451 0.70 358.24 119.28 56.72
20 INT62400 Positive_regulation of Localization of Il1 34 0.67 35.53 7.96 55.44
21 INT19775 Localization of Il1 183 0.78 145.5 50.91 55.20
22 INT846 Positive_regulation of B2M 42 0.70 29.78 8.06 50.00
23 INT23174 Gene_expression of NLRP3 51 0.72 35.49 6.47 50.00
24 INT15132 Gene_expression of TNFRSF1A 33 0.75 20.09 5.93 50.00
25 INT45818 Gene_expression of C4A 35 0.75 26.4 3.52 50.00
26 INT10612 Localization of NLRP3 13 0.78 8.91 2.27 50.00
27 INT80005 Gene_expression of MVK 4 0.09 1.79 1.34 50.00
28 INT257406 Localization of TNFRSF1A 3 0.46 2.6 0.55 50.00
29 INT257407 Localization of MVK 1 0.22 1.78 0.18 50.00
30 INT12720 Positive_regulation of Il1 246 0.70 195.97 72.05 47.16
31 INT20129 Regulation of Il1 53 0.53 44.14 19.89 39.92
32 INT6852 Localization of TNF 883 0.81 705.95 270.84 5.00
33 INT173693 Localization of Gopc 249 0.65 70.49 38.81 5.00
34 INT17886 Negative_regulation of Il1 95 0.57 70.91 31.25 5.00
35 INT56809 Binding of Tlr4 184 0.48 106.02 31.18 5.00
36 INT69035 Positive_regulation of Casp1 43 0.69 25.18 10.67 5.00
37 INT25608 Regulation of Gene_expression of Il1 37 0.44 27.76 10.1 5.00
38 INT54662 Positive_regulation of Positive_regulation of Il1 21 0.43 19.33 7.14 5.00
39 INT90077 Gene_expression of Casp1 29 0.76 20.79 6.26 5.00
40 INT114180 Negative_regulation of Il1rn 22 0.57 11.06 5.44 5.00
41 INT174688 Binding of Tlr2 45 0.42 36.65 5.25 5.00
42 INT1901 Binding of Mefv 24 0.48 32.26 4.5 5.00
43 INT126759 Negative_regulation of Nlrp3 5 0.41 2.95 1.58 5.00
44 INT53236 Positive_regulation of Binding of Il1 5 0.40 3.84 1.41 5.00
45 INT96073 Localization of Casp1 11 0.78 4.91 1.29 5.00
46 INT209915 Protein_catabolism of Il1 6 0.57 3.97 1.17 5.00
47 INT209912 Gene_expression of Pycard 17 0.22 12.04 1.04 5.00
48 INT284359 Negative_regulation of Mvk 4 0.37 6.62 0.99 5.00
49 INT317823 Positive_regulation of Negative_regulation of Mvk 2 0.30 3.33 0.62 5.00
50 INT168448 Localization of Nlrp3 5 0.73 3.75 0.58 5.00
51 INT284362 Positive_regulation of Mvk 3 0.44 3.32 0.46 5.00
52 INT298971 Positive_regulation of Localization of Casp1 2 0.06 0.97 0.28 5.00
53 INT317821 Regulation of Gene_expression of Casp1 1 0.05 1.74 0.24 5.00
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