D:Scleritis

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pChart

Disease Term
Synonyms Episcleritides, Episcleritis, Necrotizing Scleritides, Necrotizing Scleritis, Scleritides, Scleritides Necrotizing, Scleritis Necrotizing
Documents 21
Hot Single Events 4
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Scleritis. They are ordered first by their relevance to Scleritis and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT299785 CTLA4 Negative_regulation of Binding of CD28 2 0.17 1.8 0.5 5.00
2 INT181862 Binding of MPO and PRTN3 2 0.16 1.18 0.38 5.00
3 INT318299 Binding of F2 and PRTN3 1 0.01 1.92 0.33 5.00
4 INT318303 Negative_regulation of Myoz1 Negative_regulation of Transcription of IL2 1 0.00 0.75 0.21 5.00
5 INT318298 MECOM Negative_regulation of Binding of CD28 1 0.00 1.08 0.18 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Scleritis. They are ordered first by their pain relevance and then by number of times they were reported in Scleritis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT16996 Gene_expression of PRTN3 113 0.75 85.61 22.57 96.88
2 INT16997 Binding of PRTN3 34 0.48 33.44 6.45 93.28
3 INT5117 Negative_regulation of Gene_expression of IL2 118 0.59 52.33 29.96 91.60
4 INT5116 Gene_expression of IL2 670 0.78 291.13 146.69 91.04
5 INT7538 Negative_regulation of IL2 95 0.57 47.31 31.7 70.24
6 INT105670 Gene_expression of AAVS1 131 0.75 49.24 12.95 58.64
7 INT10870 Regulation of IgG 67 0.59 43.27 12.74 36.56
8 INT52907 Regulation of Gene_expression of HLA-DRA 28 0.34 5.94 5.96 36.56
9 INT16364 Gene_expression of HLA-DRA 234 0.78 118.81 45.01 36.00
10 INT4509 Gene_expression of IgG 426 0.76 293.69 56.64 35.72
11 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210 20.92
12 INT103245 Positive_regulation of Gene_expression of MMP9 64 0.68 36.86 15.7 20.92
13 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 20.52
14 INT73048 Gene_expression of MMP9 268 0.77 159.75 57.81 20.52
15 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 5.00
16 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98 5.00
17 INT6481 Binding of TNF 624 0.48 510.2 214.82 5.00
18 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 5.00
19 INT11051 Positive_regulation of Gene_expression of IL6 415 0.69 319.21 109.3 5.00
20 INT145266 Gene_expression of IL17A 154 0.75 109.83 45.33 5.00
21 INT9239 Regulation of Gene_expression of IL6 106 0.61 75.24 36.53 5.00
22 INT23222 Binding of Phax 52 0.31 7.61 30.4 5.00
23 INT899 Gene_expression of F13A1 122 0.70 78.02 16.26 5.00
24 INT153776 Positive_regulation of IL17A 42 0.64 34.58 14.82 5.00
25 INT67855 Negative_regulation of PPIG 64 0.57 17.83 13.54 5.00
26 INT91703 Negative_regulation of Myoz1 78 0.58 53.78 13.5 5.00
27 INT60764 Positive_regulation of PPIG 39 0.67 17.08 13.48 5.00
28 INT51014 Transcription of IL2 42 0.71 21.56 12.7 5.00
29 INT50580 Binding of PPIG 39 0.36 11.17 12.34 5.00
30 INT16772 Gene_expression of MPO 81 0.78 90.98 11.9 5.00
31 INT4047 Binding of F13A1 105 0.43 66.54 11.81 5.00
32 INT70877 Gene_expression of PPIG 72 0.75 22.39 10.93 5.00
33 INT73504 Binding of CD28 35 0.45 15.99 10.04 5.00
34 INT44602 Gene_expression of TNFSF13B 37 0.75 30.98 9.96 5.00
35 INT56223 Positive_regulation of MPO 35 0.70 43 8.2 5.00
36 INT155010 Positive_regulation of Gene_expression of IL17A 23 0.64 20.17 7.15 5.00
37 INT16214 Localization of F13A1 36 0.74 21.8 4.87 5.00
38 INT211133 Negative_regulation of MTX1 8 0.19 3.86 4.87 5.00
39 INT67279 Localization of PRTN3 11 0.50 14.18 4.3 5.00
40 INT150222 Positive_regulation of Gene_expression of TNFSF13B 12 0.11 7.49 2.43 5.00
41 INT144652 Negative_regulation of Binding of CD28 6 0.55 3.09 2.28 5.00
42 INT171010 Binding of IL5 6 0.36 4.11 2.12 5.00
43 INT254308 Negative_regulation of TNFSF13B 10 0.42 5.12 1.25 5.00
44 INT182852 Regulation of AAVS1 4 0.12 4.6 1.03 5.00
45 INT190418 Positive_regulation of AAVS1 15 0.49 4.71 0.98 5.00
46 INT154180 Negative_regulation of SYK 3 0.43 4.67 0.5 5.00
47 INT153313 Regulation of Localization of F13A1 2 0.36 2.34 0.48 5.00
48 INT318301 Negative_regulation of DHODH 1 0.03 0.6 0.44 5.00
49 INT229392 Negative_regulation of Positive_regulation of MPO 2 0.20 2.18 0.32 5.00
50 INT182854 Negative_regulation of AAVS1 4 0.06 1.98 0.15 5.00
51 INT25074 Regulation of Gene_expression of F13A1 2 0.33 1.15 0.14 5.00
52 INT318300 Binding of CD52 1 0.10 1.16 0.07 5.00
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