D:Sclerosis

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pChart

Disease Term
Synonyms Scleroses
Documents 1132
Hot Single Events 200
Hot Interactions 12

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Sclerosis. They are ordered first by their relevance to Sclerosis and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT350163 Regulation of Binding of DURS1 and ELOVL1 1 0.00 1.48 0.11 99.12
2 INT161387 Binding of PNOC and GTPBP4 1 0.03 1.05 0.59 98.88
3 INT350164 Binding of DURS1 and ELOVL1 1 0.00 1.47 0.11 98.46
4 INT273235 Binding of Cdk5 and Cdk5r1 1 0.24 6.06 0.46 97.20
5 INT273232 Negative_regulation of Binding of Cdk5 and Cdk5r1 1 0.28 3.16 0.23 97.20
6 INT291394 Gene_expression of HTT Negative_regulation of Gene_expression of Slc1a2 1 0.11 0.96 0.34 92.80
7 INT144589 Binding of YY1 and Oprl1 1 0.04 0.73 0.13 92.44
8 INT347165 Binding of NOTCH1 and PAX5 1 0.05 0.86 0.03 85.76
9 INT347163 NOTCH1 Positive_regulation of MSC 1 0.03 0.85 0.03 85.76
10 INT347164 NOTCH1 Negative_regulation of Gene_expression of EBF1 1 0.03 0.85 0.03 85.76
11 INT131185 PTH Positive_regulation of Gene_expression of IGF1 3 0.44 3.31 1.31 82.72
12 INT169646 Binding of Csrp1 and Il6 1 0.00 1.69 0.36 80.48
13 INT291387 Cntf Positive_regulation of Slc1a2 1 0.12 0.34 0.45 70.08
14 INT187388 Esr2 Positive_regulation of Gene_expression of Pgr 1 0.00 0.8 0.03 69.96
15 INT291384 Cntf Positive_regulation of Slc1a3 1 0.26 0.34 0.45 69.28
16 INT265646 Binding of Mapk1 and Mapk14 1 0.01 1.53 0.46 68.84
17 INT265647 Binding of Ephb1 and Mapk1 1 0.00 1.48 0.43 68.84
18 INT209881 Binding of TNFRSF11B and TNFSF11 8 0.36 8.92 0.86 66.48
19 INT224423 Binding of TNFRSF11B and TNFRSF11A 3 0.19 2.36 0.37 66.48
20 INT276391 Prdm1 Regulation of TSC1 1 0.00 1.29 0.09 66.04
21 INT276304 PRDM1 Regulation of TSC1 1 0.01 1.29 0.09 65.80
22 INT210597 Negative_regulation of Binding of TNFSF11 and TNFRSF11A 3 0.26 5.66 0.33 64.88
23 INT182636 Binding of TNFSF11 and TNFRSF11A 16 0.29 17.5 0.84 64.44
24 INT131184 PTGER2 Positive_regulation of Gene_expression of IGF1 1 0.63 2.47 1.29 62.12
25 INT276375 Binding of Prdm1 and MIR9-1 1 0.12 1.12 0.08 56.92
26 INT276334 Binding of Prdm1 and Mirlet7a-1 1 0.12 1.13 0.08 56.92
27 INT276383 Binding of PRDM1 and Mirlet7a-1 1 0.39 1.12 0.08 56.68
28 INT276384 Binding of Mirlet7a-1 and MIR9-1 1 0.39 1.12 0.08 55.96
29 INT333396 CFD Positive_regulation of Bcl2l1 1 0.05 0.98 0.13 55.88
30 INT255384 Binding of AKR1C2 and DSG1 1 0.01 1.54 0 51.84
31 INT252421 Gja1 Regulation of P2ry1 1 0.00 0.28 0.09 38.20
32 INT184540 Agt Regulation of Gene_expression of Ccl2 1 0.08 1.66 0.18 37.08
33 INT273237 Cdk5 Positive_regulation of Protein_catabolism of Grin2b 1 0.45 1.31 0.22 31.16
34 INT320810 Protein_catabolism of COL1A2 Positive_regulation of Localization of CYP27A1 1 0.04 1.05 0.4 28.68
35 INT276377 Binding of Lgals1 and KRT20 1 0.00 1.11 0.03 26.48
36 INT276305 Binding of LGALS1 and KRT20 1 0.01 1.11 0.03 26.00
37 INT84426 Binding of TSPO and INSRR 1 0.01 0.22 0.3 25.00
38 INT333393 CFD Positive_regulation of Gene_expression of Timp1 1 0.07 0.82 0.16 22.24
39 INT350169 Binding of DMD and MRI1 1 0.11 3.08 0.54 21.44
40 INT292882 Binding of S100A12 and TP63 1 0.06 0.51 0 9.52
41 INT95730 Binding of CP and SPINK1 2 0.19 5.65 4.02 5.00
42 INT130721 Binding of IL1B and IL1RN 6 0.05 5.29 2.85 5.00
43 INT122163 Binding of TNF and TNFRSF1B 6 0.44 6.06 2.41 5.00
44 INT238914 Positive_regulation of CNR1 Positive_regulation of Phosphorylation of MAPK1 1 0.19 3.22 2.35 5.00
45 INT197379 Tbs1 Positive_regulation of Ltp 6 0.07 1.87 2.21 5.00
46 INT319581 Binding of PIAS1 and TNFSF14 1 0.02 1.58 2.13 5.00
47 INT148704 Binding of TNF and TNFRSF1A 5 0.44 3.3 2.09 5.00
48 INT285569 TNF Negative_regulation of Gene_expression of Il6 1 0.03 2.83 1.46 5.00
49 INT186355 Il23a Positive_regulation of Gene_expression of Il17a 4 0.12 3 1.24 5.00
50 INT311914 Il1 Negative_regulation of Gene_expression of Col2a1 1 0.01 1.94 1.23 5.00
51 INT247469 RCT Regulation of OAP 1 0.02 1.8 1.19 5.00
52 INT330379 Gene_expression of IL10 Negative_regulation of Positive_regulation of MAPK14 1 0.00 1.95 1.18 5.00
53 INT203168 PTGER2 Negative_regulation of Gene_expression of ALOX5AP 1 0.03 2.4 1.18 5.00
54 INT238916 CNR1 Positive_regulation of Phosphorylation of MAPK1 1 0.19 1.61 1.17 5.00
55 INT290667 Il6 Positive_regulation of Stat3 3 0.69 2.42 1.15 5.00
56 INT230019 Binding of HLA-B and ERAL1 1 0.00 2.23 1.1 5.00
57 INT203178 IL18 Positive_regulation of Gene_expression of Lts1 1 0.01 1.98 1.02 5.00
58 INT81127 Binding of Gabrd and Abat 3 0.25 0 0.96 5.00
59 INT203162 PTGER2 Regulation of Gene_expression of ALOX5AP 1 0.04 1.47 0.94 5.00
60 INT285561 Il23a Positive_regulation of Gene_expression of Il22 2 0.06 2.45 0.93 5.00
61 INT219154 Binding of HMGB1 and TLR4 2 0.17 4.45 0.93 5.00
62 INT277832 Binding of TNFRSF1B and NPEPPS 1 0.01 1.1 0.88 5.00
63 INT277831 Binding of TNFRSF1A and NPEPPS 1 0.01 1.1 0.87 5.00
64 INT261783 Bdnf Regulation of Gene_expression of Slc12a5 1 0.09 0 0.87 5.00
65 INT186672 IL8 Positive_regulation of Transcription of PTH 1 0.01 1.83 0.85 5.00
66 INT261786 Bdnf Negative_regulation of Slc12a5 1 0.14 0.05 0.85 5.00
67 INT203164 PTGER2 Regulation of ALOX5 1 0.00 0.9 0.78 5.00
68 INT203171 PTGER2 Negative_regulation of ALOX5 1 0.01 0.89 0.77 5.00
69 INT186674 Binding of BGLAP and CYP27A1 1 0.01 1.91 0.71 5.00
70 INT184125 Il12a Positive_regulation of Stat4 2 0.11 1.04 0.7 5.00
71 INT285562 Binding of Il27ra and Il27 1 0.10 2.19 0.67 5.00
72 INT285467 Negative_regulation of Binding of IL1B and IL1RN 1 0.05 1.33 0.61 5.00
73 INT224419 Binding of NFKB2 and TNFRSF11B 1 0.11 1.37 0.6 5.00
74 INT224420 Regulation of Binding of NFKB2 and TNFRSF11B 1 0.13 1.39 0.6 5.00
75 INT201512 Binding of PRSS1 and hcp 1 0.09 1.9 0.57 5.00
76 INT291386 Cntf Regulation of Gene_expression of Gria2 1 0.11 0.13 0.53 5.00
77 INT270044 Il10 Positive_regulation of Positive_regulation of Hmox1 1 0.20 1.59 0.53 5.00
78 INT240537 Binding of Il12a and Ebi3 1 0.08 1.23 0.49 5.00
79 INT229127 SPINK1 Positive_regulation of PRSS1 1 0.53 1.59 0.48 5.00
80 INT229128 Binding of CP and PRSS1 1 0.14 0.77 0.47 5.00
81 INT203177 Negative_regulation of CPOX Positive_regulation of Gene_expression of Lts1 1 0.00 0.72 0.46 5.00
82 INT254360 Binding of EPAS1 and HIF1A 3 0.39 3.36 0.46 5.00
83 INT263917 Binding of SST and Sstr5 2 0.02 0.56 0.45 5.00
84 INT290671 Binding of Socs3 and Stat3 2 0.23 1.59 0.45 5.00
85 INT206538 Trem2 Regulation of Gene_expression of Cd80 1 0.17 1.26 0.44 5.00
86 INT261782 Bdnf Positive_regulation of Gene_expression of Slc12a5 1 0.18 0 0.44 5.00
87 INT206536 Trem2 Positive_regulation of Gene_expression of Cd80 1 0.30 1.26 0.44 5.00
88 INT270043 Binding of Ldlr and Hdl1 1 0.01 2.3 0.43 5.00
89 INT184543 Agt Positive_regulation of Ccl2 1 0.16 3.18 0.43 5.00
90 INT186673 IL8 Positive_regulation of Positive_regulation of PTH 1 0.01 0.92 0.42 5.00
91 INT291393 Cntf Regulation of GTS 1 0.05 0 0.42 5.00
92 INT238913 MAPK3 Regulation of Positive_regulation of MAPK1 1 0.11 0.39 0.42 5.00
93 INT203163 LTB4R Regulation of Gene_expression of ALOX5 1 0.00 0.98 0.41 5.00
94 INT261790 SHC1 Positive_regulation of Slc12a5 1 0.02 0.06 0.41 5.00
95 INT181995 TIMP1 Negative_regulation of Mmp9 1 0.01 1.38 0.4 5.00
96 INT296945 ADIPOQ Negative_regulation of TNF 1 0.03 1.13 0.4 5.00
97 INT285560 Il23a Positive_regulation of Il17a 1 0.09 1.45 0.39 5.00
98 INT203167 Gene_expression of PTGER2 Positive_regulation of Gene_expression of ALOX5AP 1 0.03 0.67 0.38 5.00
99 INT285571 Binding of IL8 and Il17a 1 0.04 1.03 0.38 5.00
100 INT261788 Bdnf Regulation of Slc12a5 1 0.10 0.07 0.38 5.00
101 INT291616 Cby1 Positive_regulation of Gene_expression of Smad7 1 0.00 0.79 0.38 5.00
102 INT285568 Binding of TNF and Tnfsf10 1 0.12 1.39 0.36 5.00
103 INT285557 Eae2 Positive_regulation of Cia1 1 0.02 1.85 0.36 5.00
104 INT285465 IL7 Positive_regulation of TNF 1 0.04 0.67 0.35 5.00
105 INT285570 Binding of IL8 and Cdkn1c 1 0.11 0.76 0.34 5.00
106 INT273234 Negative_regulation of Cdk5 Positive_regulation of Ptprs 1 0.14 1.26 0.34 5.00
107 INT236955 Binding of Cxcr5 and Cxcl13 1 0.28 2.26 0.34 5.00
108 INT203166 Negative_regulation of CPOX Positive_regulation of Gene_expression of LTB4R 1 0.00 0.65 0.34 5.00
109 INT285565 Positive_regulation of Zeb1 Negative_regulation of IL2 1 0.02 0.62 0.33 5.00
110 INT285558 Binding of Il11ra1 and Il27 1 0.05 1.1 0.33 5.00
111 INT285566 F8 Negative_regulation of IL2 1 0.00 0.62 0.33 5.00
112 INT285563 Zeb1 Negative_regulation of IL2 1 0.01 0.62 0.33 5.00
113 INT353362 amd Negative_regulation of Cxcr4 1 0.04 0.52 0.33 5.00
114 INT330377 Positive_regulation of Binding of TLR2 and TLR9 1 0.09 2.79 0.32 5.00
115 INT330381 Binding of TLR2 and TLR9 1 0.07 2.77 0.32 5.00
116 INT203089 Binding of Il1a and Traf6 1 0.04 0.66 0.32 5.00
117 INT203085 Positive_regulation of Binding of Il1a and Myd88 1 0.07 0.65 0.32 5.00
118 INT330389 Positive_regulation of Binding of TLR2 and TLR8 1 0.08 2.78 0.32 5.00
119 INT206208 MRO Negative_regulation of CD24 1 0.02 1.87 0.32 5.00
120 INT203086 Positive_regulation of Binding of Il1a and Traf6 1 0.06 0.67 0.32 5.00
121 INT203087 Binding of Il1a and Myd88 1 0.05 0.65 0.31 5.00
122 INT285567 Binding of IL1B and Cdc42 1 0.03 0.77 0.31 5.00
123 INT285564 Binding of IL1B and Ripk2 1 0.04 0.76 0.31 5.00
124 INT330383 Binding of TLR2 and TLR3 1 0.07 2.77 0.31 5.00
125 INT330378 Positive_regulation of Binding of TLR2 and TLR3 1 0.10 2.78 0.31 5.00
126 INT330387 Binding of TLR2 and TLR8 1 0.06 2.77 0.31 5.00
127 INT229635 SPINK5 Positive_regulation of NF1 1 0.01 2.17 0.3 5.00
128 INT224422 Regulation of Binding of NFKB2 and TNFSF11 1 0.13 0.69 0.3 5.00
129 INT333398 CFD Negative_regulation of Gene_expression of Pdgfa 1 0.02 0.64 0.3 5.00
130 INT224418 Binding of NFKB2 and TNFSF11 1 0.11 0.68 0.3 5.00
131 INT203169 CPOX Regulation of Gene_expression of PTGER2 2 0.00 0.48 0.29 5.00
132 INT203170 Negative_regulation of CPOX Positive_regulation of ALOX5 1 0.01 0.53 0.29 5.00
133 INT291383 Fig4 Regulation of Gene_expression of Cntf 1 0.10 0 0.28 5.00
134 INT333246 Binding of Cxcr4 and Cxcl12 3 0.34 0.99 0.27 5.00
135 INT270046 Ido1 Positive_regulation of Positive_regulation of Hmox1 1 0.15 0.8 0.27 5.00
136 INT206535 Binding of Trem2 and Tg(CAG-EGFP)D4Nagy 1 0.03 0.5 0.27 5.00
137 INT311918 Insrr Negative_regulation of Tgfbr1 1 0.00 0.87 0.26 5.00
138 INT311902 Acvrl1 Negative_regulation of Tgfbr1 1 0.13 0.87 0.26 5.00
139 INT279828 Binding of Scn1a and Scn9a 1 0.39 1.64 0.26 5.00
140 INT311900 Acvrl1 Negative_regulation of Insrr 1 0.00 0.86 0.25 5.00
141 INT203165 Binding of IL10 and PTGER2 1 0.01 0.5 0.25 5.00
142 INT287794 Binding of IGHG3 and AIP 1 0.05 2.8 0.24 5.00
143 INT229129 SPINK1 Negative_regulation of PRSS1 1 0.49 0.79 0.24 5.00
144 INT123462 Binding of TNF and Tnfrsf11b 3 0.21 3.52 0.24 5.00
145 INT311911 Tgfbr1 Positive_regulation of Gene_expression of Mmp13 1 0.10 0.55 0.23 5.00
146 INT216911 Positive_regulation of P2rx7 Positive_regulation of Localization of Plg 1 0.02 0.13 0.23 5.00
147 INT311908 Acvrl1 Positive_regulation of Gene_expression of Mmp13 1 0.10 0.55 0.23 5.00
148 INT203176 PTGER2 Regulation of Gene_expression of Lts1 1 0.00 0.37 0.23 5.00
149 INT240539 Il12a Positive_regulation of Stat3 1 0.11 0.75 0.22 5.00
150 INT333394 CFD Negative_regulation of Gene_expression of Cat 1 0.03 0.79 0.22 5.00
151 INT206540 mc Positive_regulation of Gene_expression of Cd80 1 0.01 0.62 0.22 5.00
152 INT333397 CFD Negative_regulation of Gene_expression of Nos2 1 0.04 0.8 0.22 5.00
153 INT240538 Il12a Positive_regulation of Phosphorylation of Stat4 1 0.11 0.76 0.22 5.00
154 INT206541 mc Regulation of Gene_expression of Cd80 1 0.00 0.62 0.22 5.00
155 INT330382 IFNA1 Positive_regulation of Gene_expression of IL10 1 0.06 0.83 0.21 5.00
156 INT240535 Il12a Positive_regulation of Tyk2 1 0.10 0.75 0.21 5.00
157 INT336946 Binding of ITGA4 and VCAM1 1 0.03 2.02 0.21 5.00
158 INT240536 Il12a Positive_regulation of Jak2 1 0.10 0.74 0.21 5.00
159 INT261787 Positive_regulation of Bdnf Positive_regulation of Fig4 1 0.02 0.77 0.2 5.00
160 INT206539 Trem2 Positive_regulation of Phosphorylation of Mapk1 1 0.22 0.62 0.2 5.00
161 INT285979 Ros1 Positive_regulation of Trib3 2 0.02 2.18 0.2 5.00
162 INT330371 Binding of TLR3 and Ifx 1 0.17 1.12 0.2 5.00
163 INT261784 Positive_regulation of Bdnf Positive_regulation of Slc12a5 1 0.15 0.77 0.2 5.00
164 INT311923 OAP Positive_regulation of Gtf3a 1 0.00 0.7 0.19 5.00
165 INT229634 GOPC Positive_regulation of GAST 1 0.09 0.47 0.19 5.00
166 INT203088 Il1a Positive_regulation of Gene_expression of Mmp3 1 0.03 0.26 0.18 5.00
167 INT290672 Stat3 Negative_regulation of Il6 1 0.08 0.4 0.18 5.00
168 INT276301 Binding of CCL21 and CXCL13 1 0.04 1.85 0.18 5.00
169 INT353361 Positive_regulation of Binding of Cxcr4 and Cxcl12 1 0.46 0 0.17 5.00
170 INT290670 Binding of Nos2 and Ppara 1 0.17 0.41 0.16 5.00
171 INT232386 Binding of CD22 and SYCP3 1 0.37 0.86 0.16 5.00
172 INT353861 Binding of Mgp and Phdlc1 1 0.01 5.09 0.16 5.00
173 INT330388 Binding of PTPRC and TLR2 1 0.00 1.19 0.16 5.00
174 INT263901 Binding of Ighg1 and Slc3a2 1 0.00 0.89 0.16 5.00
175 INT208217 IRF6 Positive_regulation of Gene_expression of ISYNA1 1 0.00 0.54 0.16 5.00
176 INT282708 Binding of MAPT and Y301C7L 1 0.00 0.54 0.16 5.00
177 INT206212 UTS2R Positive_regulation of CD24 1 0.09 0.71 0.15 5.00
178 INT353359 Binding of Cxcl12 and Regulation of Nes 1 0.25 0.3 0.15 5.00
179 INT353360 Binding of Cxcl12 and Positive_regulation of Gene_expression of Hist1h3f 1 0.03 0.3 0.15 5.00
180 INT279829 Scn1a Regulation of Gene_expression of Scn9a 1 0.42 1.52 0.15 5.00
181 INT273238 Grin1 Positive_regulation of Ptprs 1 0.07 0.51 0.14 5.00
182 INT259023 CADPS Positive_regulation of Binding of SH2B2 1 0.06 2.05 0.14 5.00
183 INT309779 PTH Negative_regulation of Gene_expression of COL5A2 1 0.00 0.52 0.14 5.00
184 INT206209 MRO Negative_regulation of Transcription of CD24 1 0.02 0.76 0.14 5.00
185 INT349758 Gal Positive_regulation of Galr1 1 0.37 0.44 0.14 5.00
186 INT332689 Binding of Edn1 and Ros1 1 0.08 0.71 0.14 5.00
187 INT273233 Negative_regulation of Cdk5 Negative_regulation of Positive_regulation of Ltp 1 0.20 0.39 0.13 5.00
188 INT330370 Positive_regulation of Binding of IL10 and Il4 1 0.01 0.47 0.13 5.00
189 INT311905 Binding of Runx2 and Smad1 1 0.12 0.46 0.13 5.00
190 INT330369 Binding of IL10 and Il4 1 0.01 0.47 0.13 5.00
191 INT311912 Gene_expression of Smad1 Positive_regulation of Gene_expression of Mmp13 1 0.08 0.51 0.12 5.00
192 INT273239 Cdk5 Positive_regulation of Positive_regulation of GRIN1 1 0.51 0.37 0.12 5.00
193 INT261789 PDGFA Positive_regulation of Slc12a5 1 0.07 0.15 0.12 5.00
194 INT289793 Binding of Comp and Ecm1 1 0.05 2.5 0.12 5.00
195 INT289794 Binding of Comp and Fn1 1 0.07 2.59 0.12 5.00
196 INT332687 Ros1 Positive_regulation of Crk 1 0.17 0.77 0.12 5.00
197 INT332685 Trib3 Positive_regulation of Binding of Ros1 1 0.01 0.74 0.12 5.00
198 INT220905 Cfb Positive_regulation of C3 1 0.06 0.91 0.11 5.00
199 INT330380 CD40 Regulation of Gene_expression of IFNA1 1 0.17 0.78 0.1 5.00
200 INT273236 Cdk5 Positive_regulation of Car2 1 0.13 0.45 0.1 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Sclerosis. They are ordered first by their pain relevance and then by number of times they were reported in Sclerosis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT127244 Binding of APOL1 1 0.33 3.29 0.09 100.00
2 INT157666 Positive_regulation of GOPC 335 0.60 120.19 42.75 100.00
3 INT203890 Positive_regulation of Gene_expression of Cdk5r1 9 0.40 9.13 1.11 99.92
4 INT49266 Positive_regulation of Arigg4 37 0.47 53.79 11.2 99.88
5 INT49488 Gene_expression of mMCP-7 37 0.75 26.11 7.68 99.88
6 INT16167 Negative_regulation of DMD 186 0.57 108.71 15.25 99.76
7 INT134468 Gene_expression of Cdk5r1 26 0.48 27.09 5.2 99.72
8 INT67912 Gene_expression of GRIN1 75 0.77 28.99 29.28 99.64
9 INT131187 Regulation of Gene_expression of IGF1 18 0.62 11.18 3.05 99.60
10 INT9682 Positive_regulation of IGF1 238 0.70 120.03 26.36 99.60
11 INT3361 Positive_regulation of Esr1 273 0.69 208.53 44.81 99.52
12 INT18833 Positive_regulation of LTB4R 19 0.69 27.61 10.17 99.32
13 INT170025 Gene_expression of Fig4 588 0.67 183.27 113.32 99.24
14 INT148495 Regulation of Cdk5 6 0.58 5.42 3.95 99.24
15 INT11203 Gene_expression of BCR 30 0.75 33.49 1.22 99.08
16 INT85983 Gene_expression of ELSPBP1 3 0.29 1.32 0.08 99.04
17 INT16166 Positive_regulation of DMD 348 0.67 133.22 15.06 98.96
18 INT64484 Binding of PNOC 12 0.33 5.51 10.86 98.88
19 INT161389 Regulation of Binding of PNOC 1 0.21 1.06 0.59 98.88
20 INT57618 Binding of GTPBP4 9 0.43 1.61 1.87 98.88
21 INT711 Positive_regulation of PIK3C2A 83 0.70 76.87 13.18 98.88
22 INT40478 Negative_regulation of NCOR2 23 0.48 12.77 14.56 98.64
23 INT17401 Gene_expression of IGF1 475 0.78 232.18 62.07 98.48
24 INT1724 Negative_regulation of ACE 437 0.59 315.64 74.48 98.36
25 INT107386 Negative_regulation of AGTR1 37 0.55 35.94 5.15 98.36
26 INT1760 Gene_expression of PTGER2 524 0.57 226.94 96.4 98.34
27 INT92288 Binding of Igfals 3 0.13 3.14 1 98.12
28 INT121241 Positive_regulation of P2rx7 65 0.69 40.94 13.59 97.96
29 INT1876 Positive_regulation of HLA-B 82 0.69 52.16 21.08 97.96
30 INT77756 Positive_regulation of GTPBP4 16 0.11 2.6 7.29 97.92
31 INT201632 Positive_regulation of Cdk5r1 20 0.40 21.6 2.75 97.84
32 INT115386 Gene_expression of Ppara 779 0.77 549.99 128.36 97.72
33 INT236916 Gene_expression of Ccnd2 5 0.46 2.48 0.14 97.60
34 INT53434 Positive_regulation of T 7 0.07 3.67 2.09 97.56
35 INT206982 Negative_regulation of TDO2 2 0.19 1.51 0 97.56
36 INT20976 Binding of CRYGS 39 0.46 5.4 20.09 97.52
37 INT2611 Negative_regulation of AQP1 17 0.39 10.04 2.15 97.52
38 INT211054 Positive_regulation of AQP1 3 0.33 4.53 1.41 97.52
39 INT211055 Binding of PAX5 2 0.33 0.85 0.18 97.52
40 INT211048 Negative_regulation of Binding of PAX5 1 0.29 0.1 0.05 97.52
41 INT211050 Positive_regulation of Binding of PAX5 1 0.34 0.1 0.05 97.52
42 INT615 Regulation of Alb 66 0.62 33.43 15.33 97.44
43 INT20102 Gene_expression of Serpine1 102 0.78 65.99 12.61 97.28
44 INT71115 Positive_regulation of Gene_expression of Serpine1 20 0.70 15.32 1.97 97.28
45 INT134472 Binding of Cdk5r1 4 0.26 4.25 0.65 97.20
46 INT96937 Gene_expression of Mmp9 191 0.75 150.3 56.01 97.12
47 INT113606 Positive_regulation of Gene_expression of Mmp9 46 0.64 44 15.07 97.12
48 INT45238 Gene_expression of Hfe 3 0.71 2.16 0.21 97.12
49 INT41590 Positive_regulation of PAX5 10 0.42 3.1 0.91 96.96
50 INT192687 Negative_regulation of PAX5 9 0.40 1.42 0.08 96.96
51 INT65733 Positive_regulation of Cnr1 125 0.70 40.27 67.33 96.84
52 INT136927 Gene_expression of HGS 18 0.70 14.42 0.6 96.76
53 INT148494 Binding of Cdk5 6 0.40 5.97 2.31 96.48
54 INT128353 Negative_regulation of Car3 16 0.37 4.93 4.61 96.38
55 INT159119 Negative_regulation of Car1 17 0.37 6.6 4.01 96.38
56 INT269896 Positive_regulation of Gene_expression of Smad2 9 0.40 2.15 0.69 96.32
57 INT442 Localization of PDYN 99 0.81 11.87 72.75 96.28
58 INT194504 Gene_expression of Smad2 27 0.65 7.45 2.25 96.28
59 INT265318 Negative_regulation of Gene_expression of Smad2 8 0.26 2.16 0.72 96.28
60 INT17233 Positive_regulation of Localization of PDYN 9 0.69 2.84 10.06 96.28
61 INT93533 Positive_regulation of Tnfsf11 53 0.50 36.93 10.53 96.16
62 INT8350 Regulation of LOC360919 3 0.36 0.45 0.41 96.08
63 INT8352 Regulation of Positive_regulation of LOC360919 1 0.36 0.35 0.1 96.08
64 INT167038 Binding of Aip 2 0.21 2.13 0.19 96.00
65 INT196733 Gene_expression of Cdk5 25 0.76 18.25 2.64 95.84
66 INT23956 Negative_regulation of DES 12 0.42 10.84 1.82 95.76
67 INT273230 Negative_regulation of Cdk5r1 1 0.25 4.48 0.53 95.72
68 INT613 Gene_expression of Alb 268 0.78 149.84 42.78 95.60
69 INT154301 Negative_regulation of Nphs1 2 0.58 2.41 0.18 95.52
70 INT154297 Negative_regulation of Gene_expression of Nphs1 2 0.58 2.43 0.15 95.52
71 INT276321 Transcription of Ccr4 1 0.09 1.04 0.07 95.52
72 INT276306 Transcription of Il2ra 1 0.07 1.04 0.07 95.52
73 INT276315 Transcription of Tnfrsf4 1 0.05 1.04 0.07 95.52
74 INT276341 Transcription of CTLA4 1 0.30 1.04 0.07 95.52
75 INT35866 Transcription of IGHE 9 0.60 12.83 2.19 95.44
76 INT35716 Positive_regulation of NCOR2 45 0.60 18 23.54 95.40
77 INT262109 Positive_regulation of Mgp 2 0.63 42.44 0.9 95.32
78 INT96532 Negative_regulation of Gene_expression of Slc1a2 24 0.59 14.22 17.91 95.24
79 INT74826 Gene_expression of Slc1a2 131 0.78 61.83 100.84 95.24
80 INT115385 Negative_regulation of Ppara 154 0.58 129.05 27.58 95.24
81 INT96533 Gene_expression of Slc1a3 72 0.78 26.85 55.31 95.24
82 INT128013 Negative_regulation of Gene_expression of Slc1a3 20 0.59 10.65 16.13 95.24
83 INT1108 Gene_expression of PPY 58 0.75 36.57 10.76 95.20
84 INT12818 Regulation of IgG-2a 9 0.37 3.23 6.07 95.20
85 INT82650 Gene_expression of Bcl2 312 0.78 211.71 55.03 95.20
86 INT86673 Positive_regulation of Bcl2 77 0.70 57.74 17.37 95.20
87 INT49750 Negative_regulation of CPOX 735 0.58 360.06 274.19 95.12
88 INT2391 Negative_regulation of PTGS1 501 0.59 207.62 205.6 95.12
89 INT154302 Gene_expression of Nphs1 4 0.77 7.37 0.41 95.00
90 INT90670 Positive_regulation of KRT1 10 0.44 6.25 1.16 94.88
91 INT11729 Regulation of IGF1 71 0.61 44.58 9.71 94.84
92 INT154550 Positive_regulation of Mal 1 0.00 1.32 0.13 94.80
93 INT151289 Gene_expression of Mal 4 0.51 2.17 0.12 94.80
94 INT154554 Gene_expression of RHOH 3 0.75 3.26 0.24 94.44
95 INT6488 Gene_expression of Tnf 484 0.78 339.61 191.58 94.44
96 INT126457 Gene_expression of BCL6 34 0.66 22.45 1.75 94.44
97 INT154548 Gene_expression of Pim1 1 0.02 1.26 0.12 94.44
98 INT93485 Negative_regulation of Slc1a2 27 0.59 10.65 20.9 94.28
99 INT4216 Gene_expression of CD40LG 328 0.78 256.02 44.23 94.24
100 INT81530 Gene_expression of Nfkb1 93 0.78 48.58 32.58 94.24
101 INT1118 Gene_expression of C6orf25 73 0.77 47.24 9.1 94.24
102 INT22132 Positive_regulation of CAT 41 0.67 18.64 10.67 93.64
103 INT1761 Positive_regulation of PTGER2 135 0.49 90.17 26.26 93.60
104 INT127555 Negative_regulation of Cdk5 59 0.59 50.2 8.45 93.28
105 INT8351 Positive_regulation of LOC360919 11 0.57 10.6 1.24 93.24
106 INT112989 Gene_expression of AIP 3 0.56 25.4 4.23 93.20
107 INT666 Gene_expression of Jun 124 0.78 54.61 33.67 93.08
108 INT28122 Gene_expression of MSC 111 0.58 26.83 6.57 93.00
109 INT142972 Gene_expression of ID2 6 0.54 5.92 0.49 93.00
110 INT26477 Regulation of ACE 26 0.45 16.31 4.33 92.96
111 INT133118 Negative_regulation of FAAH 25 0.59 13.05 9.37 92.92
112 INT216107 Gene_expression of Imraq1 30 0.08 6.11 0.8 92.92
113 INT216106 Positive_regulation of Gene_expression of Imraq1 6 0.05 2 0.19 92.92
114 INT10248 Gene_expression of KRT20 436 0.78 231.96 32.88 92.88
115 INT36201 Gene_expression of ETFA 8 0.66 9.18 0.58 92.88
116 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 92.88
117 INT92388 Gene_expression of ALK 16 0.78 22.46 2.26 92.88
118 INT68695 Gene_expression of HTT 63 0.77 44.54 3.69 92.80
119 INT291388 Negative_regulation of Gene_expression of HTT 1 0.41 0.95 0.32 92.80
120 INT22804 Positive_regulation of ALDOC 8 0.41 8.07 1.02 92.76
121 INT233816 Negative_regulation of PTH1R 2 0.58 4.08 1.07 92.72
122 INT181614 Positive_regulation of TDO2 2 0.45 2.18 0.18 92.72
123 INT191125 Gene_expression of Igfals 12 0.25 12.96 2.89 92.68
124 INT1212 Binding of Oprl1 312 0.48 28.6 225.15 92.44
125 INT6437 Binding of YY1 154 0.47 26.3 90.46 92.44
126 INT121388 Positive_regulation of BCL6 2 0.28 2.71 0.32 92.44
127 INT30312 Binding of Pdyn 30 0.37 4.2 18.23 92.40
128 INT15516 Gene_expression of Crp 711 0.77 615.33 173.09 92.32
129 INT79723 Positive_regulation of Sod2 34 0.70 24.61 3.92 92.32
130 INT310250 Regulation of TLE1 1 0.00 0.68 0.37 92.32
131 INT39758 Gene_expression of Fn1 57 0.65 34.38 6.02 92.24
132 INT154549 Positive_regulation of Pim1 1 0.02 1.3 0.13 92.16
133 INT122039 Positive_regulation of Gene_expression of Ppara 144 0.68 113.55 28.55 92.04
134 INT5010 Gene_expression of Calca 197 0.78 85.76 118.75 92.04
135 INT144646 Positive_regulation of Rela 53 0.67 27.78 13.2 92.00
136 INT252723 Gene_expression of SYK 3 0.25 2.67 0.23 92.00
137 INT152437 Localization of SPINK5 4 0.54 3.97 0.69 91.68
138 INT154553 Positive_regulation of RHOH 3 0.45 2.76 0.29 91.60
139 INT39712 Binding of pad 82 0.48 110.92 10.33 91.60
140 INT89824 Gene_expression of HSD17B1 5 0.75 2.69 1.66 91.56
141 INT1635 Gene_expression of Vip 245 0.78 53.36 88.13 91.44
142 INT62511 Negative_regulation of MCS 20 0.50 6.77 2.35 91.36
143 INT347185 Gene_expression of MYBL1 1 0.12 0.9 0 91.28
144 INT51801 Gene_expression of Gabrd 64 0.72 19.17 22.61 91.16
145 INT39153 Positive_regulation of PTGS2 182 0.70 96.16 60.6 91.12
146 INT66423 Binding of ELOVL1 52 0.40 61.63 5.16 90.80
147 INT233 Binding of Gast 31 0.42 17.07 5.21 90.64
148 INT17913 Regulation of HSD11B1 87 0.60 93.23 6.04 90.64
149 INT3513 Negative_regulation of Igha 9 0.38 7.43 0.56 90.60
150 INT5008 Localization of Calca 204 0.81 80.35 125.16 90.56
151 INT62509 Gene_expression of MCS 58 0.67 21.46 6.57 90.48
152 INT19491 Gene_expression of CD19 44 0.75 28.8 3.47 90.24
153 INT122041 Binding of Ppara 308 0.48 189.17 51.48 90.12
154 INT65054 Positive_regulation of Nfkb1 285 0.70 149.33 126.73 90.00
155 INT74143 Positive_regulation of Positive_regulation of Atm 1 0.31 0.79 0.15 89.76
156 INT350166 Regulation of Negative_regulation of DURS1 1 0.20 1.58 0.12 89.68
157 INT19963 Gene_expression of COL1A1 118 0.59 42.11 15.15 89.60
158 INT210578 Gene_expression of PAX5 5 0.44 3.46 0.12 89.52
159 INT107643 Positive_regulation of Positive_regulation of Arigg4 2 0.02 1.72 0.25 89.52
160 INT119400 Phosphorylation of Car2 19 0.52 8.47 11.63 89.32
161 INT196870 Positive_regulation of Phosphorylation of Car2 6 0.26 3.43 2.63 89.32
162 INT230881 Gene_expression of HTL 5 0.10 2.51 0.28 89.20
163 INT23072 Positive_regulation of Atm 2 0.40 1.76 0.24 89.20
164 INT242264 Binding of ACAT1 3 0.12 1.05 0.06 89.12
165 INT48540 Gene_expression of Kcna5 37 0.77 14.04 16.07 89.04
166 INT65629 Positive_regulation of Gene_expression of Kcna5 5 0.69 2.48 2.76 89.04
167 INT43557 Binding of RTCA 3 0.17 1.59 1.34 88.96
168 INT43552 Negative_regulation of Binding of RTCA 2 0.03 1.15 0.87 88.96
169 INT59175 Localization of TNMD 4 0.70 4.14 0.71 88.92
170 INT15529 Gene_expression of GCG 51 0.75 18.55 8.35 88.80
171 INT3537 Positive_regulation of Car2 413 0.56 103.51 94.35 88.72
172 INT197196 Negative_regulation of DURS1 2 0.43 30.6 2.37 88.64
173 INT138872 Gene_expression of SPINK5 21 0.58 30.11 4.12 88.32
174 INT191745 Regulation of Gene_expression of Nphs1 1 0.15 2.96 0 87.96
175 INT756 Gene_expression of C3 138 0.75 100.6 19.2 87.76
176 INT5116 Gene_expression of IL2 670 0.78 291.13 146.69 87.68
177 INT5056 Gene_expression of IFNG 216 0.78 137.52 74.57 87.68
178 INT56298 Gene_expression of IL4 306 0.78 182.18 72.92 87.68
179 INT20375 Gene_expression of Hand1 213 0.60 148.51 54.53 87.68
180 INT100939 Gene_expression of Il13 176 0.73 125.1 43.38 87.68
181 INT69157 Gene_expression of IL5 127 0.77 102.58 26.81 87.68
182 INT92653 Gene_expression of IL12B 21 0.75 17.28 3.89 87.68
183 INT54615 Gene_expression of GPER 25 0.75 8.23 2.27 87.68
184 INT89826 Transcription of HSD17B1 5 0.69 2.75 1.71 87.56
185 INT184549 Positive_regulation of Gpbar1 1 0.13 10.35 0.19 87.56
186 INT156131 Binding of Hand2 14 0.25 10.35 3.99 87.16
187 INT309781 Positive_regulation of Gene_expression of PTH1R 2 0.46 1.88 0.87 87.16
188 INT353858 Binding of Mgp 1 0.38 7.16 0.11 87.00
189 INT4991 Positive_regulation of Vim 74 0.69 69.84 8.33 86.72
190 INT337100 Gene_expression of Mgp 3 0.71 45.04 1.64 86.60
191 INT120807 Binding of NOL3 10 0.45 3.62 3.97 86.40
192 INT161391 Negative_regulation of Binding of NOL3 1 0.34 0.8 0.48 86.40
193 INT191830 Regulation of Airn 3 0.38 1.82 0.09 86.40
194 INT236824 Negative_regulation of Gene_expression of PTH1R 10 0.58 9.3 3.42 86.28
195 INT60860 Gene_expression of Slmap 32 0.66 8.55 1.34 85.96
196 INT172328 Negative_regulation of Phl1 1 0.03 61.51 0.97 85.88
197 INT233812 Gene_expression of PTH1R 32 0.77 18.15 6.15 85.80
198 INT158426 Binding of NOTCH1 10 0.36 7.95 0.45 85.76
199 INT95271 Negative_regulation of Nos3 46 0.53 24.1 9.71 85.60
200 INT113948 Gene_expression of FLNA 32 0.73 36.06 4.81 85.56
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