D:Seasonal Affective Disorder

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Disease Term
Synonyms Affective Disorder Seasonal, Affective Disorders Seasonal, Disorder Seasonal Affective, DISORDER SEASONAL MOOD, Disorders Seasonal Affective, Disorders Seasonal Mood, MOOD DISORDER SEASONAL, MOOD DISORDERS SEASONAL, SAD SEASONAL AFFECTIVE DISORDER, Seasonal Affective Disorders, SEASONAL DEPRESSION
Documents 17
Hot Single Events 3
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Seasonal Affective Disorder. They are ordered first by their relevance to Seasonal Affective Disorder and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT304577 Binding of Arntl and Clock Regulation of Gene_expression of Maoa 1 0.01 0.3 0.44 37.00
2 INT304576 Binding of Arntl and Clock 6 0.37 0.43 0.5 34.56
3 INT304575 Creb1 Regulation of Gene_expression of Bdnf 1 0.04 1 0.84 5.00
4 INT304578 Negative_regulation of HDAC9 Positive_regulation of Gene_expression of Bdnf 1 0.06 0.9 0.49 5.00
5 INT177440 Binding of HPSE and Gnrh1 1 0.00 1.82 0.45 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Seasonal Affective Disorder. They are ordered first by their pain relevance and then by number of times they were reported in Seasonal Affective Disorder. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT939 Gene_expression of PAEP 86 0.77 31.02 8.59 99.36
2 INT37204 Gene_expression of HCL1 4 0.65 0.76 1.54 89.44
3 INT10787 Gene_expression of Gnrh1 64 0.78 23.06 6.76 84.20
4 INT170385 Regulation of Clock 29 0.49 4.95 6.39 75.36
5 INT96338 Gene_expression of HPSE 17 0.75 18.71 2.73 66.32
6 INT177439 Negative_regulation of Positive_regulation of HPSE 1 0.21 1.48 0.32 55.84
7 INT30014 Positive_regulation of HPSE 22 0.70 20.91 4.09 55.52
8 INT62154 Gene_expression of Datd 8 0.67 1.28 3.91 45.76
9 INT30817 Gene_expression of Th 142 0.76 33.56 38.12 44.76
10 INT2396 Regulation of Maoa 25 0.62 6.04 13.27 37.00
11 INT2397 Gene_expression of Maoa 12 0.77 11.85 3.88 37.00
12 INT304568 Regulation of Gene_expression of Maoa 1 0.03 0.24 0.43 37.00
13 INT304570 Regulation of Binding of Arntl 2 0.26 0.35 0.43 35.32
14 INT304572 Regulation of Binding of Clock 1 0.30 0.29 0.43 35.32
15 INT290803 Binding of Arntl 10 0.37 1.82 1.34 34.56
16 INT248971 Binding of Clock 8 0.34 1.12 0.73 34.56
17 INT57734 Binding of SLC6A4 36 0.48 11.94 15.42 30.36
18 INT127435 Gene_expression of Per1 89 0.77 13.94 22.31 30.00
19 INT149818 Gene_expression of Clock 81 0.70 14.15 10.04 30.00
20 INT127434 Negative_regulation of Gene_expression of Per1 12 0.58 2.58 4.2 30.00
21 INT128328 Gene_expression of Arntl 44 0.74 3.77 2.63 30.00
22 INT196971 Positive_regulation of Gene_expression of Per1 8 0.69 1.23 2.44 30.00
23 INT149815 Positive_regulation of Gene_expression of Clock 7 0.46 0.87 1.45 30.00
24 INT206674 Positive_regulation of Gene_expression of Arntl 6 0.67 0.6 0.52 30.00
25 INT292834 Negative_regulation of Gene_expression of Arntl 6 0.43 0.87 0.49 30.00
26 INT204005 Negative_regulation of Gene_expression of Clock 3 0.39 0.58 0.45 30.00
27 INT13838 Positive_regulation of Drd1a 48 0.70 9.83 23.42 26.80
28 INT104760 Localization of MT1A 13 0.44 1.5 4.85 25.32
29 INT11087 Positive_regulation of Drd2 54 0.69 12.4 31.43 24.60
30 INT188646 Binding of MT1A 1 0.05 0.62 0 23.28
31 INT119711 Positive_regulation of Slc6a4 16 0.69 4.44 5.21 20.16
32 INT188645 Binding of ALOX12 2 0.30 3.07 0.09 18.80
33 INT10783 Negative_regulation of Gnrh1 24 0.59 7.9 6.2 13.52
34 INT74509 Positive_regulation of Datd 2 0.18 0.85 1.81 13.36
35 INT438 Gene_expression of Crh 376 0.78 159.11 169.17 5.00
36 INT5497 Positive_regulation of Crh 299 0.70 125.54 131.14 5.00
37 INT7395 Localization of GNRH1 399 0.81 62.88 117.68 5.00
38 INT92669 Gene_expression of Bdnf 309 0.78 178.26 116.68 5.00
39 INT1438 Localization of Pomc 360 0.81 101.26 116.47 5.00
40 INT920 Localization of PLOD1 223 0.81 42.25 78.7 5.00
41 INT102020 Gene_expression of Creb1 190 0.78 57.31 59.77 5.00
42 INT82055 Positive_regulation of Creb1 176 0.70 60.2 58.39 5.00
43 INT66040 Positive_regulation of Bdnf 114 0.69 67.67 51.81 5.00
44 INT921 Regulation of GH1 172 0.60 52.88 51.04 5.00
45 INT1199 Positive_regulation of INS 579 0.70 399.64 50.43 5.00
46 INT106554 Positive_regulation of Gene_expression of Bdnf 73 0.70 42.58 30.77 5.00
47 INT7975 Regulation of PLOD1 97 0.62 20.9 30.51 5.00
48 INT91775 Gene_expression of Slc6a4 102 0.78 26.45 28.23 5.00
49 INT5135 Negative_regulation of GNRH1 106 0.58 36.63 27.71 5.00
50 INT56053 Negative_regulation of Bdnf 77 0.58 64.4 26.83 5.00
51 INT1638 Negative_regulation of PLOD1 92 0.59 21.69 26.61 5.00
52 INT11303 Gene_expression of Avp 116 0.78 39.23 23.88 5.00
53 INT102021 Positive_regulation of Gene_expression of Creb1 66 0.70 24.04 23.28 5.00
54 INT1644 Regulation of FSHR 77 0.55 15.62 21.49 5.00
55 INT8075 Localization of Crh 64 0.81 25.41 19.45 5.00
56 INT5372 Localization of LHB 55 0.68 9.47 19 5.00
57 INT1642 Negative_regulation of Localization of PLOD1 40 0.58 10.67 17.95 5.00
58 INT133647 Negative_regulation of HDAC9 149 0.57 106.84 17.9 5.00
59 INT106556 Negative_regulation of Gene_expression of Bdnf 42 0.59 34.71 17.64 5.00
60 INT102903 Regulation of Gene_expression of Bdnf 35 0.62 20.1 17.42 5.00
61 INT66039 Positive_regulation of Ntrk2 53 0.69 15.87 17.23 5.00
62 INT124371 Negative_regulation of Gsk3b 170 0.55 87.92 15.51 5.00
63 INT26538 Positive_regulation of FSHR 103 0.69 30.95 15.33 5.00
64 INT4145 Gene_expression of FSHR 124 0.77 44.98 13.04 5.00
65 INT100096 Regulation of Slc6a4 24 0.62 7.25 12.28 5.00
66 INT147583 Gene_expression of AIS 82 0.58 48.7 7.11 5.00
67 INT57293 Regulation of Gnrh1 21 0.62 7.29 5.41 5.00
68 INT122675 Negative_regulation of Gene_expression of Slc6a4 14 0.59 6.4 4.69 5.00
69 INT6021 Binding of PRL 18 0.48 12.55 4.3 5.00
70 INT61734 Regulation of HPSE 16 0.60 13.05 3.5 5.00
71 INT124438 Regulation of Gene_expression of Slc6a4 9 0.62 3.5 2.97 5.00
72 INT16015 Negative_regulation of Localization of LHB 10 0.37 2.95 2.9 5.00
73 INT178457 Positive_regulation of LIFR 12 0.56 3.98 2.9 5.00
74 INT178458 Negative_regulation of LIFR 13 0.47 8.75 2.48 5.00
75 INT15607 Localization of GNRHR 14 0.62 7.56 2.3 5.00
76 INT12033 Binding of PLOD1 15 0.48 8.04 2.3 5.00
77 INT79606 Negative_regulation of NAT2 5 0.59 0.31 2.1 5.00
78 INT30153 Regulation of PTHLH 13 0.58 7.72 1.87 5.00
79 INT94524 Gene_expression of MT1A 6 0.39 1.66 1.75 5.00
80 INT304571 Phosphorylation of H3 10 0.35 1.76 1.69 5.00
81 INT33496 Positive_regulation of Gene_expression of FSHR 14 0.46 6.05 1.66 5.00
82 INT304573 Positive_regulation of Phosphorylation of H3 1 0.10 1.39 1.58 5.00
83 INT192673 Gene_expression of Hdac5 6 0.61 2.84 1.51 5.00
84 INT169914 Positive_regulation of H3 7 0.23 1.98 1.38 5.00
85 INT258053 Positive_regulation of Negative_regulation of HDAC9 8 0.27 7.37 1.23 5.00
86 INT9730 Binding of LHB 4 0.35 2.38 1.19 5.00
87 INT192675 Positive_regulation of Gene_expression of Hdac5 2 0.33 2.52 1.13 5.00
88 INT85963 Gene_expression of LIFR 23 0.75 9 0.98 5.00
89 INT44446 Regulation of Regulation of PLOD1 3 0.38 1.85 0.97 5.00
90 INT75676 Transcription of Gnrh1 3 0.71 1.81 0.9 5.00
91 INT32963 Negative_regulation of Localization of GNRHR 3 0.29 2.48 0.84 5.00
92 INT178455 Localization of LIFR 6 0.61 2.24 0.83 5.00
93 INT169941 Negative_regulation of Positive_regulation of H3 2 0.14 1.22 0.82 5.00
94 INT304567 Negative_regulation of Hdac5 1 0.18 0.62 0.75 5.00
95 INT178456 Positive_regulation of Gene_expression of LIFR 7 0.50 2.74 0.54 5.00
96 INT177436 Binding of HPSE 2 0.47 1.81 0.52 5.00
97 INT177437 Transcription of HPSE 2 0.23 3.44 0.41 5.00
98 INT177438 Negative_regulation of GNRHR 3 0.18 3.39 0.4 5.00
99 INT341030 Gene_expression of EMD 1 0.55 0.64 0.28 5.00
100 INT341032 Negative_regulation of Gene_expression of EMD 1 0.35 0.64 0.28 5.00
101 INT341031 Negative_regulation of EMD 1 0.35 0.58 0.26 5.00
102 INT178453 Regulation of LIFR 3 0.50 0.31 0.03 5.00
103 INT178454 Regulation of Positive_regulation of LIFR 1 0.37 0.19 0 5.00
104 INT178452 Negative_regulation of Positive_regulation of LIFR 1 0.35 0.19 0 5.00
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