D:Seborrhea

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Disease Term
Synonyms Cradle Cap, Dermatitides Seborrheic, Dermatitis Seborrheic, Dermatitis Seborrheica, Excess Sebum Production, Excessive Sebum Production, Sbd, SEBORRHEIC, Seborrheic Dermatitides, Seborrheic Dermatitis, Seborrheic Diathesis
Documents 69
Hot Single Events 21
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Seborrhea. They are ordered first by their relevance to Seborrhea and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT329794 TLR2 Positive_regulation of Positive_regulation of IL12A 1 0.01 1.05 0.44 5.00
2 INT329803 TLR2 Positive_regulation of Positive_regulation of IL6 1 0.01 0.94 0.41 5.00
3 INT329800 TLR2 Positive_regulation of Positive_regulation of IL8 1 0.01 0.99 0.41 5.00
4 INT329801 Binding of CAMP and IFNA1 1 0.03 1.48 0.4 5.00
5 INT329799 Binding of CD14 and LY96 2 0.04 1.02 0.39 5.00
6 INT329795 IL6 Positive_regulation of Transcription of CCL5 1 0.02 0.59 0.17 5.00
7 INT329796 TICAM1 Positive_regulation of IFNA1 2 0.02 0.89 0.15 5.00
8 INT329797 Positive_regulation of TLR2 Positive_regulation of Gene_expression of IL6 1 0.02 1.67 0.11 5.00
9 INT329802 Positive_regulation of TLR2 Regulation of Gene_expression of IL6 1 0.01 1.67 0.11 5.00
10 INT329798 Binding of MYD88 and TICAM1 2 0.01 0.24 0.1 5.00
11 INT213903 Binding of EGFR and ERBB2 10 0.37 5.03 0.04 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Seborrhea. They are ordered first by their pain relevance and then by number of times they were reported in Seborrhea. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT177992 Positive_regulation of SNRNP70 28 0.49 16.14 4.28 100.00
2 INT63779 Localization of Ado 6 0.64 4.8 3.81 100.00
3 INT238522 Localization of ATG9A 1 0.54 3.68 0.27 100.00
4 INT122812 Gene_expression of SNRNP70 130 0.75 67 12.5 100.00
5 INT156180 Positive_regulation of Gene_expression of SNRNP70 14 0.49 4.54 2.13 100.00
6 INT238521 Positive_regulation of Localization of ATG9A 1 0.34 1.91 0.16 100.00
7 INT9098 Positive_regulation of DBP 30 0.69 15.77 4.26 100.00
8 INT115908 Localization of TCO 3 0.48 1.76 1.39 99.88
9 INT7376 Positive_regulation of CAMP 17 0.67 6.39 6.6 99.04
10 INT171666 Regulation of GOPC 117 0.39 40.41 15.47 98.94
11 INT15610 Localization of GOPC 223 0.65 68.26 28.7 98.80
12 INT223597 Negative_regulation of Binding of EGFR 12 0.43 7.97 0.23 96.68
13 INT11154 Binding of EGFR 149 0.48 96.23 6.29 96.32
14 INT52962 Binding of ERBB2 77 0.47 50.03 1.49 96.32
15 INT5117 Negative_regulation of Gene_expression of IL2 118 0.59 52.33 29.96 93.88
16 INT5116 Gene_expression of IL2 670 0.78 291.13 146.69 93.52
17 INT68496 Binding of PGR 26 0.48 16.36 2.09 92.84
18 INT292006 Gene_expression of ADSL 8 0.22 2.55 0.26 91.20
19 INT292007 Positive_regulation of ADSL 2 0.20 1.03 0.03 90.76
20 INT86383 Negative_regulation of EGFR 258 0.59 173.94 13.32 86.76
21 INT227699 Gene_expression of ATG9A 3 0.46 1.95 0.25 82.52
22 INT292008 Negative_regulation of CELSR2 1 0.01 1.73 0 77.96
23 INT28325 Negative_regulation of Tst 13 0.51 12.41 3.16 76.36
24 INT11159 Gene_expression of EGFR 698 0.78 548.93 25.69 74.56
25 INT4144 Gene_expression of SHBG 64 0.68 39.94 6.08 70.24
26 INT66191 Gene_expression of DBP 42 0.66 22.25 3.18 70.24
27 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 62.40
28 INT159472 Localization of NPPB 32 0.79 33.67 3.59 60.64
29 INT5135 Negative_regulation of GNRH1 106 0.58 36.63 27.71 57.44
30 INT25271 Positive_regulation of MTG1 21 0.67 13.59 5.96 57.32
31 INT177438 Negative_regulation of GNRHR 3 0.18 3.39 0.4 56.96
32 INT23212 Positive_regulation of Rac1 46 0.55 32.85 15.1 48.64
33 INT1118 Gene_expression of C6orf25 73 0.77 47.24 9.1 48.24
34 INT4216 Gene_expression of CD40LG 328 0.78 256.02 44.23 47.08
35 INT125007 Gene_expression of DEFB1 30 0.60 4.14 1.32 41.76
36 INT180883 Positive_regulation of MT1E 7 0.27 4.63 0.11 39.84
37 INT292009 Localization of ADSL 3 0.20 1.92 0 39.12
38 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 18.56
39 INT157664 Positive_regulation of DEFB4A 15 0.56 10.87 3.8 16.12
40 INT263027 Positive_regulation of DEFB103A 5 0.45 2.89 0.92 16.12
41 INT262875 Positive_regulation of DEFA1 2 0.17 0.58 0.06 16.12
42 INT24889 Negative_regulation of CABIN1 36 0.48 16.76 4.73 9.28
43 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 5.00
44 INT720 Positive_regulation of POMC 807 0.70 237.37 353.83 5.00
45 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98 5.00
46 INT6852 Localization of TNF 883 0.81 705.95 270.84 5.00
47 INT10832 Gene_expression of IL8 1050 0.78 698.72 270 5.00
48 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97 5.00
49 INT6481 Binding of TNF 624 0.48 510.2 214.82 5.00
50 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210 5.00
51 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 5.00
52 INT867 Gene_expression of IFNA1 930 0.78 594.85 168.03 5.00
53 INT9660 Regulation of TNF 363 0.62 312.94 139.99 5.00
54 INT17612 Gene_expression of CRP 676 0.78 580.61 119.03 5.00
55 INT50674 Gene_expression of PTGS2 459 0.78 253.33 118.51 5.00
56 INT12339 Localization of IL8 437 0.81 251.87 117.39 5.00
57 INT60526 Gene_expression of IL10 449 0.78 292.71 107.84 5.00
58 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 5.00
59 INT12082 Localization of IL6 365 0.81 241.78 105.78 5.00
60 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74 5.00
61 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 5.00
62 INT10838 Positive_regulation of IL8 381 0.70 295.51 101.62 5.00
63 INT9236 Regulation of Gene_expression of TNF 204 0.62 162.66 72.99 5.00
64 INT10837 Positive_regulation of Gene_expression of IL8 294 0.70 190.08 70.34 5.00
65 INT5058 Positive_regulation of IFNA1 356 0.70 245.75 60.52 5.00
66 INT546 Binding of ALB 311 0.48 85.98 60.14 5.00
67 INT117223 Gene_expression of TLR4 348 0.78 206.18 54.42 5.00
68 INT22112 Positive_regulation of Localization of TNF 164 0.70 115.66 52.18 5.00
69 INT52264 Gene_expression of IK 180 0.77 90.87 51.87 5.00
70 INT6473 Positive_regulation of Gene_expression of IL1B 204 0.70 117.23 50.86 5.00
71 INT1199 Positive_regulation of INS 579 0.70 399.64 50.43 5.00
72 INT9210 Regulation of IL6 166 0.62 125.61 49.95 5.00
73 INT375 Positive_regulation of REN 293 0.70 152.46 47.55 5.00
74 INT20345 Gene_expression of Dbi 136 0.78 56.41 46.2 5.00
75 INT145266 Gene_expression of IL17A 154 0.75 109.83 45.33 5.00
76 INT18522 Positive_regulation of Gene_expression of IFNA1 248 0.67 160.85 44.87 5.00
77 INT61619 Gene_expression of IL12A 194 0.77 146.07 41.97 5.00
78 INT5973 Regulation of IL1B 109 0.62 66.6 39.88 5.00
79 INT88322 Gene_expression of CCR5 111 0.78 77.36 39.84 5.00
80 INT3758 Gene_expression of ALB 326 0.78 184.65 38.75 5.00
81 INT9239 Regulation of Gene_expression of IL6 106 0.61 75.24 36.53 5.00
82 INT133028 Gene_expression of TLR2 209 0.73 131.92 36.17 5.00
83 INT72651 Gene_expression of TH1L 114 0.75 80.15 35.15 5.00
84 INT6484 Binding of IL1B 122 0.47 75.84 35.07 5.00
85 INT52350 Gene_expression of CD14 184 0.75 71.37 33.13 5.00
86 INT7538 Negative_regulation of IL2 95 0.57 47.31 31.7 5.00
87 INT22211 Positive_regulation of CYP3A4 110 0.70 22 28.27 5.00
88 INT12129 Gene_expression of CYP3A4 107 0.78 23.11 27.6 5.00
89 INT5206 Gene_expression of AR 316 0.78 113.83 27.29 5.00
90 INT3760 Positive_regulation of ALB 142 0.70 87.46 26.7 5.00
91 INT19856 Gene_expression of CD8A 240 0.75 147.86 26.39 5.00
92 INT10836 Negative_regulation of IL8 95 0.59 52.59 24.71 5.00
93 INT10835 Regulation of IL8 79 0.49 53.04 24.14 5.00
94 INT55583 Localization of IFNA1 135 0.78 85.07 24.13 5.00
95 INT3330 Gene_expression of AGT 149 0.76 98.65 22.73 5.00
96 INT69322 Negative_regulation of MAPK14 70 0.54 42.92 22.71 5.00
97 INT5328 Positive_regulation of CD4 191 0.69 133.43 21.31 5.00
98 INT85952 Positive_regulation of AR 168 0.67 64.36 20.66 5.00
99 INT52457 Gene_expression of ABCB1 129 0.78 38.68 19.88 5.00
100 INT117220 Positive_regulation of TLR4 64 0.69 53.61 17.33 5.00
101 INT1533 Negative_regulation of AGT 105 0.42 46.54 16.92 5.00
102 INT45142 Gene_expression of DCPS 109 0.56 84.71 16.87 5.00
103 INT13510 Gene_expression of ERBB2 530 0.78 405.68 16.79 5.00
104 INT12087 Regulation of Localization of TNF 44 0.62 28.71 15.17 5.00
105 INT89293 Positive_regulation of Gene_expression of CCR5 29 0.70 22.14 15 5.00
106 INT61624 Positive_regulation of Gene_expression of IL12A 50 0.56 33.07 13.07 5.00
107 INT117222 Positive_regulation of Gene_expression of TLR4 80 0.70 51.6 12.9 5.00
108 INT14510 Gene_expression of SOD1 208 0.76 88.56 12.4 5.00
109 INT102731 Regulation of ABCB1 29 0.62 5.36 11.67 5.00
110 INT102272 Regulation of TH1L 41 0.44 30.89 11.63 5.00
111 INT19795 Positive_regulation of EGFR 161 0.70 103.69 11.55 5.00
112 INT25963 Gene_expression of DES 122 0.75 98.81 11.25 5.00
113 INT62895 Gene_expression of NOSTRIN 51 0.75 28.8 10.68 5.00
114 INT133030 Positive_regulation of Gene_expression of TLR2 53 0.65 38.15 10.65 5.00
115 INT58904 Localization of TH1L 40 0.68 27.11 10.52 5.00
116 INT150540 Binding of TLR2 50 0.45 35.86 10.43 5.00
117 INT159631 Positive_regulation of DCPS 60 0.27 43.23 10.3 5.00
118 INT95565 Positive_regulation of IL12A 47 0.56 33.96 10.16 5.00
119 INT123142 Gene_expression of DEFB4A 54 0.76 36.14 10.02 5.00
120 INT81929 Negative_regulation of Gene_expression of IL10 41 0.57 27.99 9.87 5.00
121 INT13085 Positive_regulation of ACE 50 0.70 44.2 8.31 5.00
122 INT91667 Localization of IL12A 39 0.74 25.51 7.36 5.00
123 INT91758 Binding of CCR5 28 0.45 20.16 7.07 5.00
124 INT81493 Transcription of CCL2 20 0.65 13.63 6.78 5.00
125 INT137206 Positive_regulation of TLR2 47 0.65 33.36 6.4 5.00
126 INT8683 Positive_regulation of F3 31 0.67 42.89 6.21 5.00
127 INT16359 Positive_regulation of Gene_expression of AGT 30 0.49 28.27 6.14 5.00
128 INT92916 Gene_expression of Acta2 50 0.74 17.52 6.11 5.00
129 INT22128 Positive_regulation of HIVEP1 61 0.43 70.52 6.07 5.00
130 INT172084 Positive_regulation of Binding of TNF 21 0.50 15.31 6.06 5.00
131 INT117189 Binding of CXCR4 34 0.37 24.27 5.81 5.00
132 INT115370 Gene_expression of PSIP1 22 0.65 9.45 5.68 5.00
133 INT15376 Positive_regulation of Gene_expression of ERBB2 215 0.70 168.54 5.23 5.00
134 INT170470 Binding of CD14 27 0.35 14.89 5.16 5.00
135 INT246031 Gene_expression of IL22 10 0.40 9.48 5.11 5.00
136 INT60252 Binding of HIVEP1 59 0.32 65.12 5.06 5.00
137 INT99091 Regulation of AR 70 0.45 31.68 5.05 5.00
138 INT11158 Positive_regulation of Gene_expression of EGFR 165 0.70 131.26 4.93 5.00
139 INT8340 Negative_regulation of SHBG 49 0.57 35.96 4.73 5.00
140 INT4146 Binding of SHBG 49 0.47 31 4.71 5.00
141 INT5219 Negative_regulation of DBP 43 0.57 23.35 4.26 5.00
142 INT97131 Positive_regulation of CD14 25 0.67 12.03 4.21 5.00
143 INT79413 Gene_expression of CAMP 13 0.75 8.3 4.02 5.00
144 INT204529 Positive_regulation of TLR9 18 0.62 15.62 3.99 5.00
145 INT173519 Positive_regulation of Localization of IFNA1 27 0.49 24.48 3.9 5.00
146 INT68269 Gene_expression of CD99 49 0.77 47.38 3.86 5.00
147 INT172173 Protein_catabolism of TNF 16 0.96 9.95 3.79 5.00
148 INT103281 Transcription of CCL5 10 0.67 5.95 3.7 5.00
149 INT144231 Gene_expression of Il12b 18 0.75 12.93 3.65 5.00
150 INT12598 Binding of DBP 20 0.48 13.11 3.62 5.00
151 INT122448 Regulation of Gene_expression of ABCB1 13 0.62 3.67 3.5 5.00
152 INT167478 Positive_regulation of Gene_expression of DCPS 23 0.27 14.75 3.37 5.00
153 INT97138 Positive_regulation of Gene_expression of CD14 17 0.48 9.07 3.35 5.00
154 INT186805 Transcription of TLR2 12 0.63 9.66 3.04 5.00
155 INT11775 Gene_expression of Ema 39 0.65 38.12 2.99 5.00
156 INT181848 Negative_regulation of CD14 16 0.43 8.14 2.95 5.00
157 INT110233 Regulation of Gene_expression of CCR5 6 0.34 7.14 2.76 5.00
158 INT165841 Gene_expression of BPIFA4P 17 0.65 6.48 2.38 5.00
159 INT61784 Positive_regulation of CENPJ 27 0.51 11.46 2.28 5.00
160 INT59784 Binding of DES 22 0.47 19.48 2.27 5.00
161 INT105378 Regulation of IL12A 6 0.26 8.82 2.15 5.00
162 INT222903 Gene_expression of TLR1 20 0.60 8.77 1.9 5.00
163 INT15742 Negative_regulation of EPO 37 0.59 17.44 1.84 5.00
164 INT23956 Negative_regulation of DES 12 0.42 10.84 1.82 5.00
165 INT120014 Transcription of CCL3 5 0.69 3.03 1.82 5.00
166 INT48792 Regulation of ERBB2 48 0.57 36.56 1.8 5.00
167 INT95636 Gene_expression of ACTG2 23 0.44 19.87 1.75 5.00
168 INT154388 Positive_regulation of Gene_expression of DEFB4A 9 0.67 7.75 1.72 5.00
169 INT157769 Binding of LY96 8 0.47 2.5 1.59 5.00
170 INT79412 Positive_regulation of Gene_expression of CAMP 5 0.49 3.73 1.55 5.00
171 INT230 Positive_regulation of GGTLC1 14 0.68 11.78 1.55 5.00
172 INT76477 Positive_regulation of CD99 14 0.50 14.77 1.42 5.00
173 INT96838 Negative_regulation of Gene_expression of ERBB2 25 0.57 15.83 1.34 5.00
174 INT92383 Gene_expression of KRAS 38 0.65 32.94 1.32 5.00
175 INT146914 Negative_regulation of TLR2 12 0.53 7.41 1.23 5.00
176 INT295694 Localization of DNAI1 4 0.15 3.28 1.09 5.00
177 INT160576 Gene_expression of Psgb1 3 0.35 1.63 1.08 5.00
178 INT90240 Gene_expression of MYOG 19 0.75 10 1.06 5.00
179 INT144232 Negative_regulation of Gene_expression of Il12b 4 0.41 2.26 1.01 5.00
180 INT58692 Regulation of Gene_expression of CD8A 11 0.42 10.16 1 5.00
181 INT107107 Gene_expression of DEFA1 4 0.01 3.37 1 5.00
182 INT77947 Regulation of Gene_expression of IL12A 6 0.24 5.23 0.94 5.00
183 INT48066 Binding of CAMP 3 0.36 2.69 0.93 5.00
184 INT237858 Positive_regulation of MYD88 5 0.49 2.93 0.9 5.00
185 INT116314 Gene_expression of Myod1 38 0.70 16.6 0.89 5.00
186 INT117347 Positive_regulation of Positive_regulation of EGFR 15 0.69 11.17 0.84 5.00
187 INT266354 Gene_expression of S100A7 9 0.58 7.35 0.75 5.00
188 INT81396 Regulation of Gene_expression of ERBB2 14 0.43 10.73 0.74 5.00
189 INT56955 Binding of MYOG 5 0.27 2.92 0.73 5.00
190 INT92382 Positive_regulation of Gene_expression of KRAS 7 0.49 4.82 0.71 5.00
191 INT182182 Positive_regulation of Positive_regulation of DCPS 4 0.08 3.32 0.7 5.00
192 INT183979 Localization of PSIP1 2 0.73 1.37 0.59 5.00
193 INT102776 Phosphorylation of CCL2 1 0.65 1.55 0.56 5.00
194 INT148107 Binding of CDIPT 8 0.17 4.56 0.53 5.00
195 INT242887 Positive_regulation of Gene_expression of TLR1 2 0.28 1.87 0.49 5.00
196 INT7067 Negative_regulation of Gene_expression of SHBG 7 0.41 5.08 0.48 5.00
197 INT147606 Positive_regulation of TLR1 5 0.67 4.35 0.47 5.00
198 INT329817 Gene_expression of DEFB103B 1 0.01 1.18 0.43 5.00
199 INT189176 Positive_regulation of Localization of TH1L 5 0.23 2.93 0.42 5.00
200 INT98708 Binding of KRAS 13 0.47 7.47 0.39 5.00
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