D:Sepsis

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pChart

Disease Term
Synonyms Bactraemia, Bactremia, Cardiovascular Autonomic Failure, Meningococcal Sepsis, Neonatal Meningitis, Neonatal Sepsis, Septic Shock, Septic Syndrome, SEPTICAEMIA, Septicemia
Documents 4688
Hot Single Events 200
Hot Interactions 200

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Sepsis. They are ordered first by their relevance to Sepsis and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT215094 Il6 Positive_regulation of Hmgb1 1 0.18 1.84 0.17 100.00
2 INT120143 Tlr4 Negative_regulation of Gene_expression of Tnf 1 0.18 0.76 0.55 100.00
3 INT180982 SERPINC1 Negative_regulation of IRF6 Positive_regulation of IL6 1 0.00 0.54 0.24 100.00
4 INT183750 Binding of EPO and TF 1 0.42 1.21 0 100.00
5 INT253771 Gopc Positive_regulation of Hmgb1 1 0.03 1.27 0.24 99.88
6 INT253765 Apex1 Positive_regulation of Hmgb1 1 0.09 1.27 0.24 99.88
7 INT253773 TNF Positive_regulation of Hmgb1 1 0.09 1.21 0.23 99.88
8 INT350814 Negative_regulation of TNF Positive_regulation of Gene_expression of Cpox 1 0.06 1.33 0.37 99.80
9 INT350816 TNF Positive_regulation of Gene_expression of Cpox 1 0.05 1.33 0.37 99.80
10 INT244320 Tlr4 Positive_regulation of Aliq1 3 0.04 4.51 0.64 99.72
11 INT215095 Negative_regulation of Il6 Positive_regulation of Hmgb1 1 0.13 1.03 0.09 99.68
12 INT196639 Negative_regulation of NA Negative_regulation of Transcription of CFTR 1 0.02 0.63 0.03 99.60
13 INT142847 IRF6 Positive_regulation of IL6 5 0.07 1.09 0.73 99.58
14 INT84522 IRF6 Positive_regulation of Gene_expression of F3 1 0.08 0.1 0.21 99.56
15 INT262289 Regulation of Binding of PPIG and CC2D1A 1 0.01 1.52 0.13 99.50
16 INT247578 Hif1a Regulation of VEGFA 1 0.02 1.59 0.07 99.44
17 INT220285 Binding of Camp and Dob2 1 0.04 0.61 0 99.32
18 INT262290 Binding of PPIG and CC2D1A 1 0.01 1.52 0.13 99.30
19 INT230786 Binding of AGT and ACE 4 0.15 2.53 0.34 99.12
20 INT334107 Binding of APC and APCS 1 0.16 1.52 0.04 99.12
21 INT312569 IL6 Positive_regulation of Localization of ELANE 1 0.11 1.05 0.24 99.12
22 INT182126 IRF6 Positive_regulation of Gene_expression of SELE 1 0.03 0.86 0.34 98.92
23 INT220681 Binding of F10 and tf 1 0.03 1.47 0.26 98.88
24 INT247271 Tlr4 Negative_regulation of SLC43A3 1 0.00 0.34 0.19 98.88
25 INT79778 Tlr4 Positive_regulation of Localization of TNF 4 0.08 4.21 1.61 98.84
26 INT316109 TEAD1 Regulation of S100B 1 0.00 1.16 0.04 98.76
27 INT254161 Epo Positive_regulation of Nos2 1 0.37 0.54 0.05 98.72
28 INT254162 Epo Positive_regulation of NOS1 1 0.01 0.53 0.05 98.72
29 INT348789 Positive_regulation of Binding of MYD88 and Tlr4 1 0.46 0.93 0.2 98.66
30 INT220382 Cotl1 Positive_regulation of Binding of Gh1 1 0.01 0.38 0.03 98.64
31 INT285604 ROS1 Positive_regulation of Gene_expression of Tlr4 1 0.01 1.14 0.2 98.56
32 INT220385 Binding of Igf1 and Gnrhr 1 0.05 0.99 0.14 98.56
33 INT220386 Binding of Gh1 and Igf1 1 0.07 0.99 0.14 98.56
34 INT348790 Binding of MYD88 and Tlr4 1 0.35 1.84 0.4 98.42
35 INT198638 GPI Positive_regulation of Gene_expression of TNF 1 0.03 1.44 0.15 98.38
36 INT195663 APC Negative_regulation of Gene_expression of IL6 1 0.16 1.18 0.22 98.20
37 INT250730 Hmgb1 Positive_regulation of Localization of TNF 1 0.08 0.92 0.09 98.08
38 INT258017 Binding of AGT and ANGPT2 3 0.11 2.35 0.19 97.88
39 INT220388 Gh1 Regulation of Cish 1 0.03 0.29 0.28 97.88
40 INT285605 Binding of ROS1 and Tlr4 1 0.01 1.25 0.16 97.80
41 INT250729 Crlf1 Positive_regulation of Localization of TNF 1 0.02 0.92 0.09 97.64
42 INT152236 Tlr4 Regulation of Gene_expression of Nos2 3 0.19 0.64 0.82 97.56
43 INT272952 Igf1 Positive_regulation of Localization of TNF 1 0.19 1.53 0.35 97.20
44 INT268768 Mip Regulation of Positive_regulation of Ccr1 1 0.44 0.83 0.23 97.04
45 INT220289 MARS Regulation of CEBPZ 1 0.02 0.93 0.11 97.04
46 INT195705 Binding of SERPINC1 and SDC4 1 0.07 1.54 0.21 97.00
47 INT194722 Negative_regulation of MAPK1 Negative_regulation of Gene_expression of CRP 1 0.09 1.49 0.41 97.00
48 INT84523 TRAF3IP2 Regulation of Gene_expression of TF 1 0.05 0.1 0.27 96.92
49 INT84519 TRAF3IP2 Positive_regulation of Gene_expression of TF 1 0.05 0.1 0.27 96.92
50 INT316112 Binding of S100B and SAE1 1 0.05 1.5 0.08 96.84
51 INT247270 Tlr4 Negative_regulation of Cebpz 1 0.04 0.33 0.19 96.80
52 INT86951 Ads3 Positive_regulation of Gene_expression of Il10 1 0.00 0.42 0.16 96.64
53 INT179203 NLRP1 Regulation of Gene_expression of TNF 1 0.31 1.73 0.6 96.44
54 INT179201 NLRP1 Regulation of Gene_expression of IL10 1 0.06 0.77 0.36 96.44
55 INT179202 NLRP1 Regulation of Gene_expression of IL6 1 0.07 0.77 0.36 96.44
56 INT323654 Igfbp1 Negative_regulation of Binding of Igf1 and Igfbp1 1 0.21 1.14 0.29 96.32
57 INT323653 Binding of Igf1 and Igfbp1 1 0.20 1.14 0.29 96.32
58 INT215093 Tlr4 Positive_regulation of Localization of Hmgb1 1 0.32 2.9 0.68 96.24
59 INT232814 Mocos Positive_regulation of Gene_expression of Tlr4 1 0.19 0.9 0.05 96.04
60 INT179502 Binding of Cd14 and Tlr4 29 0.39 13.77 5.73 95.92
61 INT222979 Negative_regulation of Binding of COL1A1 and FN1 1 0.01 1.64 0.93 95.80
62 INT152240 Nfasc Regulation of Gene_expression of Nos2 1 0.06 0.19 0.36 95.72
63 INT180984 IRF6 Positive_regulation of Localization of IL8 7 0.11 2.13 3.47 95.68
64 INT226207 Binding of Ins1 and Positive_regulation of Pik3cb 1 0.01 2.08 0 95.60
65 INT226190 Binding of Igf1 and Positive_regulation of Pik3cb 1 0.17 1.04 0 95.60
66 INT179200 Binding of ICAM1 and IL8 1 0.03 1.02 0.25 95.52
67 INT83616 Binding of IL6 and IL8 5 0.09 5.8 1.11 95.52
68 INT194705 Negative_regulation of MAPK1 Negative_regulation of Positive_regulation of IK 1 0.00 1.46 0.41 95.40
69 INT222978 Binding of COL1A1 and FN1 1 0.01 1.64 0.92 95.40
70 INT222684 TEAD1 Negative_regulation of PROC 1 0.01 0.39 0.05 95.20
71 INT179233 IRF6 Negative_regulation of Binding of GSR 1 0.03 0.83 0.25 95.20
72 INT311997 Regulation of STAM Regulation of BGLAP 1 0.00 0.61 0.32 95.00
73 INT157767 Binding of TLR4 and LY96 8 0.54 4.05 1.95 94.88
74 INT230464 Binding of SNRNP70 and TLR1 1 0.02 1.2 0.17 94.44
75 INT230462 Binding of SNRNP70 and TH1L 1 0.00 0.99 0.08 94.44
76 INT311991 STAM Regulation of BGLAP 1 0.00 0.61 0.31 94.36
77 INT198647 TNF Positive_regulation of HIF1A 1 0.03 2.97 0.34 94.24
78 INT226206 Gtf3a Positive_regulation of Akt1 1 0.00 1.02 0 93.92
79 INT226193 Gtf3a Positive_regulation of Pik3cb 1 0.00 1.02 0 93.92
80 INT132448 MIR3607 Negative_regulation of IL6 1 0.01 2.45 0.48 93.80
81 INT345011 Binding of GSN and PTAFR 1 0.09 0.83 0.12 93.64
82 INT314756 IL6 Positive_regulation of Gene_expression of Crp 2 0.13 4.58 0.48 93.52
83 INT262307 CAPNS1 Regulation of TAF9 1 0.04 1.23 0.33 93.52
84 INT316481 Positive_regulation of Stat3 Positive_regulation of Localization of Hand1 1 0.19 1.48 0.03 93.40
85 INT84521 Binding of F7 and TF 1 0.06 0.09 0.37 93.36
86 INT325908 Binding of Wbp5 and Fgg 1 0.00 1.2 0 93.28
87 INT325906 Binding of Hps3 and Fgg 1 0.02 0.96 0 93.28
88 INT175016 Binding of REN and S100A6 2 0.11 1.13 0.37 93.20
89 INT75319 IGF1 Positive_regulation of Gh 1 0.00 0.26 0 93.20
90 INT230465 Binding of TLR1 and TH1L 1 0.09 0.99 0.08 93.12
91 INT63873 SRPX Positive_regulation of Localization of Calca 1 0.02 0.49 2.04 93.08
92 INT198653 TNF Positive_regulation of MIF 1 0.15 3.81 1.55 93.04
93 INT311811 Binding of REN and RASGRP1 1 0.16 0.68 0.08 93.00
94 INT306006 Binding of CD14 and LBP 1 0.06 0.63 0.04 93.00
95 INT114364 Hmgb1 Positive_regulation of Gene_expression of TNF 2 0.05 1.85 1.06 92.88
96 INT329311 Spp1 Positive_regulation of IFN1@ 1 0.20 1.2 0.23 92.88
97 INT325904 Binding of F2 and Wbp5 1 0.01 1.22 0 92.72
98 INT325897 Negative_regulation of Binding of F2 and Wbp5 1 0.01 0.96 0 92.72
99 INT325899 Binding of Hps3 and F2 1 0.12 2.43 0 92.72
100 INT343857 Binding of ABCC8 and LY96 1 0.02 0.96 0.34 92.64
101 INT191219 Edn1 Positive_regulation of Amigo2 1 0.06 1.26 0.07 92.32
102 INT329306 Spp1 Positive_regulation of Il12a 1 0.08 1.19 0.23 92.24
103 INT272951 Binding of TNF and Igf1 1 0.14 1.48 0.36 92.16
104 INT272953 Negative_regulation of Binding of TNF and Igf1 1 0.16 1.48 0.36 92.16
105 INT306018 Binding of Tlr4 and Tlr9 1 0.15 0.92 0.27 91.96
106 INT253764 Atp9a Positive_regulation of Apex1 1 0.00 0.39 0.08 91.92
107 INT179229 Binding of GSR and NR3C2 1 0.03 0.37 0.23 91.76
108 INT142332 Binding of SERPINH1 and TNNI3 1 0.03 1.05 0.17 91.76
109 INT293014 IRF6 Positive_regulation of Localization of CA2 1 0.04 0.71 1.02 91.56
110 INT293008 IL8 Positive_regulation of Localization of CA2 1 0.11 0.71 1.01 91.56
111 INT324828 ELANE Positive_regulation of Localization of Ecm1 1 0.00 0.61 0.09 91.52
112 INT252426 Binding of SLURP1 and Negative_regulation of Gene_expression of TNF 1 0.01 1.13 0.49 91.36
113 INT306019 Binding of Tlr4 and LY96 1 0.06 0.91 0.49 91.28
114 INT221415 IRF6 Positive_regulation of Gene_expression of IL10 2 0.05 1.73 0.75 91.04
115 INT267133 Binding of ICAM1 and VCAM1 25 0.32 25.43 1.83 90.88
116 INT195687 Binding of F13A1 and CA13 1 0.02 1.75 0 90.64
117 INT215100 Binding of Hmgb1 and Tlr4 5 0.29 3.21 1.68 90.52
118 INT348784 Ins1 Positive_regulation of Irs1 1 0.09 3.47 0.44 90.44
119 INT334423 Binding of SPINK1 and Cea 1 0.02 2.53 0.17 90.44
120 INT147755 Binding of GNRH1 and TNF 1 0.32 2.37 0.79 89.84
121 INT334102 Nos3 Positive_regulation of Gene_expression of ISYNA1 1 0.01 0.59 0 89.72
122 INT195666 Binding of PROC and THBD 2 0.40 2.42 0.56 89.64
123 INT282646 Binding of PROC and PROCR 1 0.40 0.99 0.26 89.64
124 INT343856 Binding of S100A9 and ABCC8 1 0.04 0.9 0.28 89.36
125 INT194713 MAPK1 Regulation of Gene_expression of TNF 1 0.10 1.66 0.38 89.36
126 INT171264 TNF Positive_regulation of MMP1 2 0.10 2.05 0.95 89.32
127 INT222988 TNF Positive_regulation of Protein_catabolism of COL1A1 1 0.01 1.66 0.9 89.32
128 INT195662 Binding of PROC and KAT8 1 0.10 2.25 0.12 89.04
129 INT132801 IL4 Positive_regulation of Localization of IL6 2 0.26 1.47 0.26 89.00
130 INT353041 IL4 Positive_regulation of Localization of IL1B 1 0.02 0.99 0.16 89.00
131 INT353036 IL4 Positive_regulation of Localization of IL10 1 0.03 0.99 0.16 89.00
132 INT353038 IL4 Positive_regulation of Localization of IL2 1 0.02 0.99 0.16 89.00
133 INT353039 IL4 Positive_regulation of Localization of IL8 1 0.02 0.99 0.16 89.00
134 INT262256 Binding of PROC and AMIGO2 1 0.00 0.72 0.04 88.84
135 INT178723 Binding of ALB and TNNI3 1 0.17 0.91 0 88.80
136 INT320694 C5 Regulation of Gene_expression of Il2 1 0.03 2.15 0.34 88.44
137 INT320692 C5 Regulation of Gene_expression of Il12a 1 0.03 2.15 0.34 88.44
138 INT320693 C5 Regulation of Gene_expression of Il6 1 0.04 2.15 0.34 88.44
139 INT320696 C5 Regulation of Gene_expression of TNF 1 0.34 2.15 0.34 88.44
140 INT320691 C5 Regulation of Gene_expression of Il1 1 0.06 2.15 0.34 88.44
141 INT353037 IL4 Positive_regulation of IL2 1 0.02 0.99 0.16 88.32
142 INT316203 Ghsr Positive_regulation of Transcription of Agrp 1 0.02 1.5 0.19 88.32
143 INT348785 Ins1 Positive_regulation of Phosphorylation of Akt1 1 0.17 3.5 0.42 88.12
144 INT132792 IL4 Positive_regulation of IL6 4 0.28 1.81 0.47 88.08
145 INT353040 IL4 Positive_regulation of IL8 1 0.02 0.99 0.16 88.08
146 INT282649 Binding of THBD and PROCR 1 0.40 0.97 0.26 88.08
147 INT84518 IRF6 Positive_regulation of Gene_expression of TF 1 0.14 0.09 0.41 87.84
148 INT317959 Negative_regulation of Ephb1 Negative_regulation of Cldn4 1 0.10 0.27 0.03 87.48
149 INT317961 Negative_regulation of Ephb1 Negative_regulation of Negative_regulation of Cldn4 1 0.10 0.27 0.03 87.48
150 INT317955 Negative_regulation of Ephb1 Negative_regulation of Tecr 1 0.08 0.28 0.03 87.48
151 INT293010 ELANE Regulation of Localization of LTF 1 0.00 0.54 0.67 87.48
152 INT84516 NFKB1 Positive_regulation of Gene_expression of TF 1 0.10 0.09 0.41 87.32
153 INT323611 Il1 Regulation of Hmgb1 1 0.17 2.36 0.55 87.24
154 INT232787 CYBB Positive_regulation of Positive_regulation of Hif1a 1 0.01 0.66 0.12 87.20
155 INT223523 Positive_regulation of Hmga1 Positive_regulation of Erv4 1 0.21 0.95 0 87.20
156 INT254121 Binding of Tbce and Aliq1 1 0.00 0.69 0.2 87.04
157 INT253772 Binding of THBD and Hmgb1 1 0.05 0.95 0.12 86.88
158 INT324829 ROS1 Positive_regulation of Gene_expression of Ecm1 1 0.00 0.66 0.09 86.84
159 INT283428 Negative_regulation of Binding of Lcn2 and Nt5e 1 0.06 1.09 0.15 86.72
160 INT195686 CA13 Positive_regulation of F13A1 1 0.03 1.75 0 86.56
161 INT198651 Positive_regulation of S100A12 Positive_regulation of TNF 1 0.15 1.5 0.04 86.56
162 INT198650 Positive_regulation of S100A12 Positive_regulation of IL1B 1 0.01 1.5 0.04 86.56
163 INT215101 Hmgb1 Positive_regulation of Localization of Il6 4 0.16 1.18 0.54 86.48
164 INT132445 TF Positive_regulation of IL8 1 0.11 2.23 0.46 86.40
165 INT75318 Gh Regulation of Gene_expression of IGF1 1 0.00 0.26 0 86.28
166 INT253769 Binding of Hmgb1 and Il1 1 0.01 0.27 0 85.92
167 INT132318 Ghrl Positive_regulation of Localization of GH1 5 0.32 4.49 0.84 85.12
168 INT282647 IL6 Positive_regulation of Gene_expression of F3 1 0.00 1.89 0.27 85.04
169 INT282648 IL8 Positive_regulation of Gene_expression of F3 1 0.00 1.89 0.27 84.80
170 INT198639 S100A12 Positive_regulation of TNF 1 0.15 1.49 0.04 84.80
171 INT198646 S100A12 Positive_regulation of IL1B 1 0.01 1.49 0.04 84.80
172 INT191217 Cotl1 Positive_regulation of Amigo2 1 0.02 0.61 0.03 84.68
173 INT262255 Binding of APC and F2R 1 0.05 3 0.1 84.64
174 INT195778 Binding of APC and PROCR 7 0.19 3.78 0.73 84.64
175 INT93989 Rab8a Positive_regulation of Gene_expression of Il12a 1 0.10 0.48 0.3 84.16
176 INT348786 Tlr4 Positive_regulation of Mapk8 1 0.33 1.09 0.11 84.00
177 INT250226 Binding of Camp and Rngtt 1 0.14 0.85 0.03 83.96
178 INT310311 Tlr4 Positive_regulation of Gpt 1 0.05 1.15 0.12 83.92
179 INT198649 Binding of HIF1A and MIF 1 0.01 1.53 0.18 83.88
180 INT132447 TF Positive_regulation of IL6 1 0.09 1.1 0.23 83.76
181 INT336740 Positive_regulation of Ambp Positive_regulation of Gene_expression of S100a8 1 0.02 1.3 0.12 83.76
182 INT93986 Rab8a Positive_regulation of Gene_expression of Il6 1 0.08 0.48 0.3 83.36
183 INT63874 Calca Positive_regulation of SRPX 1 0.01 0.17 0.74 83.32
184 INT283255 IRF6 Regulation of MIR15B 1 0.00 1.04 0.03 83.28
185 INT283260 TNF Positive_regulation of TNF Regulation of MIR15B 1 0.01 1.03 0.03 83.28
186 INT283253 TNF Regulation of MIR15B 1 0.01 1.03 0.03 83.28
187 INT283432 Lcn2 Negative_regulation of Binding of Lcn2 and Nt5e 1 0.07 0.38 0 83.12
188 INT149652 Zfp36 Regulation of Nos2 1 0.09 0.42 0.47 82.96
189 INT93990 Rab8a Positive_regulation of Gene_expression of Il1 1 0.05 0.48 0.3 82.88
190 INT220286 Epo Regulation of hb 1 0.23 0.21 0 82.84
191 INT285344 Il10 Negative_regulation of Gene_expression of Tnf 1 0.15 1.91 0.49 82.84
192 INT330852 Fasl Positive_regulation of TRAT1 1 0.05 0.4 0.06 82.60
193 INT296893 Nps Negative_regulation of Gene_expression of REN 1 0.00 1.05 0.04 82.36
194 INT281321 STX1A Positive_regulation of Gene_expression of tf 1 0.07 0.96 0 82.32
195 INT283252 IRF6 Regulation of MIR155 1 0.01 1.04 0.03 82.24
196 INT283257 TNF Regulation of MIR155 1 0.04 1.03 0.03 82.24
197 INT253776 Binding of THBD and F2 1 0.00 1.15 0.18 82.08
198 INT182124 Binding of IRF6 and TLR4 14 0.10 16.11 4.65 82.00
199 INT182125 Binding of CD14 and TLR4 7 0.25 3.78 1.03 82.00
200 INT317960 Negative_regulation of Ephb1 Positive_regulation of Gene_expression of Tecr 1 0.15 0.08 0 82.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Sepsis. They are ordered first by their pain relevance and then by number of times they were reported in Sepsis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT276358 Gene_expression of MIR150 42 0.74 38.44 7.82 100.00
2 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 100.00
3 INT114363 Positive_regulation of Hmgb1 50 0.67 48.92 8.15 100.00
4 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 100.00
5 INT60526 Gene_expression of IL10 449 0.78 292.71 107.84 100.00
6 INT12861 Gene_expression of Cish 40 0.57 23.01 8.48 100.00
7 INT66280 Gene_expression of Nos2 534 0.78 330.78 157.07 100.00
8 INT9659 Gene_expression of Il6 991 0.78 715.11 265.57 100.00
9 INT10832 Gene_expression of IL8 1050 0.78 698.72 270 100.00
10 INT78057 Localization of Tlr4 140 0.77 67.75 21.72 100.00
11 INT6488 Gene_expression of Tnf 484 0.78 339.61 191.58 100.00
12 INT19472 Gene_expression of Il1 554 0.76 419.75 175.35 100.00
13 INT69036 Gene_expression of IL18 99 0.77 77.92 25.95 100.00
14 INT150869 Positive_regulation of Gene_expression of Faah 4 0.70 3.78 2.2 100.00
15 INT92151 Regulation of Faah 5 0.62 6.31 3.06 100.00
16 INT77434 Positive_regulation of Gene_expression of Nos2 151 0.69 96.76 38.94 100.00
17 INT49866 Negative_regulation of Parp1 53 0.58 35.37 8.84 100.00
18 INT215085 Positive_regulation of Gene_expression of Hmgb1 17 0.63 16.81 4.13 100.00
19 INT253755 Regulation of Hmgb1 7 0.55 6.23 1.8 100.00
20 INT23775 Regulation of S100B 24 0.62 16.75 2.57 100.00
21 INT9236 Regulation of Gene_expression of TNF 204 0.62 162.66 72.99 100.00
22 INT9658 Negative_regulation of Gene_expression of Il6 110 0.59 66.29 32.58 100.00
23 INT48222 Positive_regulation of Localization of IL8 123 0.59 78.04 37.2 100.00
24 INT116736 Positive_regulation of Mif 40 0.70 31.93 15.37 100.00
25 INT10053 Localization of Paf 15 0.80 9.14 3.64 100.00
26 INT25610 Positive_regulation of Gene_expression of Il1 136 0.67 104.43 43.86 100.00
27 INT170767 Binding of UGCG 4 0.18 5.33 1.17 100.00
28 INT49104 Positive_regulation of Gene_expression of Vcam1 30 0.69 36.52 7.64 100.00
29 INT77433 Regulation of Gene_expression of Nos2 49 0.62 35.07 16.33 100.00
30 INT82168 Positive_regulation of S100b 20 0.68 9.72 3.08 100.00
31 INT86437 Binding of IL6 154 0.48 121.22 29.3 100.00
32 INT48407 Positive_regulation of Gene_expression of Icam1 61 0.70 57.91 21.54 100.00
33 INT12608 Regulation of CNR1 62 0.60 24.36 36.02 100.00
34 INT2605 Regulation of ELANE 39 0.61 18.22 7.11 100.00
35 INT10443 Regulation of Gene_expression of CNR1 10 0.50 3.96 3.06 100.00
36 INT150870 Regulation of Gene_expression of Faah 3 0.45 2.65 2.87 100.00
37 INT10444 Positive_regulation of Gene_expression of CNR1 18 0.69 8.69 7.84 100.00
38 INT22548 Positive_regulation of Casp3 483 0.70 258.78 213.07 100.00
39 INT12628 Binding of Cish 4 0.30 2.45 0.78 100.00
40 INT171975 Negative_regulation of Gene_expression of INCENP 8 0.05 5.24 1.35 100.00
41 INT224146 Positive_regulation of Gene_expression of Trem1 6 0.28 5.14 1.2 100.00
42 INT316 Regulation of Cebpz 105 0.00 27.21 35.41 100.00
43 INT191243 Binding of SAE1 4 0.35 2.88 0.29 100.00
44 INT58602 Gene_expression of HMI 34 0.65 25.26 3.74 100.00
45 INT291971 Negative_regulation of Gene_expression of HMI 3 0.08 11.81 0.59 100.00
46 INT22546 Positive_regulation of Gene_expression of Casp3 97 0.70 47.89 51.92 100.00
47 INT179221 Positive_regulation of Localization of AMIGO2 1 0.08 2.29 0.43 100.00
48 INT69181 Positive_regulation of Col3a1 10 0.33 5.54 1.91 100.00
49 INT125709 Positive_regulation of Gene_expression of Col3a1 7 0.27 5.17 0.65 100.00
50 INT179224 Localization of AMIGO2 1 0.13 2.28 0.43 100.00
51 INT51017 Positive_regulation of Icam1 113 0.70 81.16 35.55 100.00
52 INT49103 Positive_regulation of Vcam1 71 0.69 59.52 19.85 100.00
53 INT142596 Positive_regulation of Gene_expression of Tlr2 42 0.69 38.41 6.67 100.00
54 INT7464 Regulation of Mbp 25 0.62 6.62 6.43 100.00
55 INT156876 Positive_regulation of Gene_expression of Casp1 10 0.50 10.25 2.58 100.00
56 INT114874 Gene_expression of Stat3 78 0.76 53.99 9.49 100.00
57 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 99.98
58 INT215071 Positive_regulation of Localization of Hmgb1 34 0.63 22.03 4.15 99.98
59 INT21609 Positive_regulation of RASGRP1 58 0.50 40.78 5.47 99.98
60 INT118742 Positive_regulation of Tlr4 32 0.69 27.55 11.09 99.98
61 INT105287 Positive_regulation of Slco1c1 24 0.34 15.41 6.81 99.98
62 INT141611 Positive_regulation of Gene_expression of Ccr1 25 0.69 20.32 6.42 99.98
63 INT52106 Negative_regulation of Localization of IL8 57 0.52 22.81 20.8 99.98
64 INT3656 Positive_regulation of Gene_expression of Ins1 74 0.54 44.94 17.36 99.98
65 INT52800 Negative_regulation of Gene_expression of Tnf 142 0.59 92.27 55.47 99.98
66 INT9131 Positive_regulation of Prkcg 431 0.70 130.8 302.41 99.98
67 INT106340 Positive_regulation of Phosphorylation of Irs1 8 0.53 7.03 2.85 99.98
68 INT86713 Positive_regulation of Mip 10 0.67 6.44 2.63 99.98
69 INT191221 Positive_regulation of Amigo2 20 0.12 24.24 2.31 99.98
70 INT38625 Gene_expression of ELL 8 0.58 12.53 1 99.98
71 INT78741 Negative_regulation of Gene_expression of Hspa1b 2 0.43 2.83 0.17 99.98
72 INT137894 Positive_regulation of Ckmt1b 1 0.49 0.73 0.14 99.98
73 INT89794 Positive_regulation of CDKN2A 58 0.67 50.18 5.38 99.98
74 INT160673 Gene_expression of Ambp 16 0.49 19.49 2.3 99.98
75 INT187741 Gene_expression of pf 33 0.29 12.38 7.14 99.98
76 INT174663 Positive_regulation of KAT8 4 0.11 3.45 0.22 99.98
77 INT52512 Positive_regulation of SLC43A3 21 0.41 5.39 5.27 99.98
78 INT2531 Positive_regulation of Cebpz 166 0.00 43.08 38.86 99.98
79 INT66752 Positive_regulation of Transcription of Tnf 15 0.68 10.86 7.26 99.98
80 INT7412 Positive_regulation of SST 71 0.70 24.44 29.48 99.98
81 INT82153 Positive_regulation of Negative_regulation of Uqcrc2 1 0.00 0.22 0 99.98
82 INT82154 Positive_regulation of Uqcrc2 1 0.00 0.22 0 99.98
83 INT231565 Positive_regulation of YWHAE 4 0.23 3.07 0.49 99.98
84 INT16868 Gene_expression of Il6 807 0.78 499.48 256.57 99.96
85 INT11051 Positive_regulation of Gene_expression of IL6 415 0.69 319.21 109.3 99.96
86 INT3738 Regulation of Epo 25 0.61 13.73 6.18 99.96
87 INT220372 Positive_regulation of Gene_expression of Cotl1 2 0.04 0.85 0.14 99.96
88 INT115963 Negative_regulation of Gene_expression of CRH 9 0.59 4.53 1.48 99.96
89 INT5207 Negative_regulation of Alms1 70 0.41 41.56 13.68 99.96
90 INT1027 Gene_expression of Lbp 132 0.77 106.7 54.16 99.92
91 INT15516 Gene_expression of Crp 711 0.77 615.33 173.09 99.92
92 INT215074 Negative_regulation of Localization of Hmgb1 28 0.57 15.09 4 99.92
93 INT224366 Gene_expression of Ager 111 0.77 125.37 8.49 99.92
94 INT1029 Positive_regulation of Gene_expression of Lbp 17 0.50 11.03 5.18 99.92
95 INT1180 Gene_expression of Ren 63 0.77 27.33 10.51 99.92
96 INT55670 Negative_regulation of Gene_expression of Tnf 83 0.59 57.16 46.33 99.92
97 INT58288 Positive_regulation of Gene_expression of Crp 83 0.61 82.23 23.7 99.92
98 INT1116 Regulation of Ren 103 0.62 27.66 33.26 99.92
99 INT194343 Gene_expression of ABCC8 8 0.65 8.15 0.77 99.92
100 INT32188 Regulation of Atp7b 7 0.04 3.01 0.81 99.92
101 INT157342 Gene_expression of S100A9 19 0.60 21.27 3.37 99.92
102 INT23188 Localization of Serpine1 22 0.79 16.06 1.96 99.92
103 INT200601 Localization of Thbd 1 0.21 1.09 0 99.92
104 INT53083 Gene_expression of Ptgs2 153 0.78 90.04 50.39 99.92
105 INT1951 Positive_regulation of Tlr4 345 0.70 176.99 62.42 99.90
106 INT138843 Binding of CC2D1A 19 0.33 33.06 1.25 99.90
107 INT131788 Positive_regulation of NPPB 87 0.67 86.1 8.81 99.90
108 INT176892 Binding of MR1 36 0.32 15.55 2.58 99.90
109 INT134748 Positive_regulation of SV2A 7 0.46 2.89 0.82 99.90
110 INT91906 Regulation of Gene_expression of Il10 13 0.58 8.92 7.06 99.90
111 INT220376 Positive_regulation of Gene_expression of Cish 8 0.31 5.41 1.46 99.88
112 INT33768 Positive_regulation of Cysltr1 87 0.46 54.66 33.52 99.88
113 INT92129 Positive_regulation of Gene_expression of F3 13 0.08 12.13 2.02 99.88
114 INT184269 Gene_expression of HMGB1 51 0.77 42.96 4.55 99.84
115 INT6852 Localization of TNF 883 0.81 705.95 270.84 99.84
116 INT48767 Negative_regulation of NOS1 312 0.59 154.25 90.32 99.84
117 INT12339 Localization of IL8 437 0.81 251.87 117.39 99.84
118 INT283264 Gene_expression of MIR182 1 0.55 5.41 0.07 99.84
119 INT9552 Positive_regulation of TNNI3 209 0.70 128.67 19.15 99.84
120 INT9660 Regulation of TNF 363 0.62 312.94 139.99 99.84
121 INT283275 Gene_expression of MIR342 7 0.58 5.41 0.07 99.84
122 INT119195 Binding of Cotl1 11 0.14 6.77 2.21 99.84
123 INT48952 Negative_regulation of Nos2 204 0.59 101.73 53.15 99.84
124 INT86780 Positive_regulation of Hmox1 145 0.70 117.09 31.18 99.84
125 INT9235 Negative_regulation of Gene_expression of TNF 346 0.59 252.98 118.61 99.84
126 INT139896 Phosphorylation of Ins1 29 0.77 24.03 2.35 99.84
127 INT283283 Negative_regulation of MIR150 5 0.41 4.16 0.55 99.84
128 INT220366 Regulation of Gene_expression of Cish 1 0.27 2.61 0.58 99.84
129 INT21610 Positive_regulation of ANGPT2 23 0.41 13.28 3.03 99.84
130 INT52924 Negative_regulation of GSR 49 0.58 28.08 9.28 99.84
131 INT11938 Positive_regulation of Localization of Il6 61 0.70 35.72 18.25 99.84
132 INT17283 Positive_regulation of CSF1 37 0.59 24.16 10.01 99.84
133 INT106648 Positive_regulation of Socs3 5 0.67 3.65 1.92 99.84
134 INT873 Gene_expression of Gh1 130 0.76 26.15 46.75 99.84
135 INT3299 Positive_regulation of AGT 126 0.68 79.45 21.91 99.84
136 INT8662 Positive_regulation of EDN1 144 0.70 125.34 19.59 99.84
137 INT134264 Gene_expression of Trem1 18 0.43 13.26 2.72 99.84
138 INT55034 Positive_regulation of Adm 27 0.61 14.1 6.13 99.84
139 INT283269 Negative_regulation of MIR342 1 0.27 1.4 0 99.84
140 INT73497 Regulation of IL10 33 0.45 22.6 9.19 99.84
141 INT58563 Negative_regulation of S100B 13 0.51 11.75 1.77 99.84
142 INT96063 Positive_regulation of Phosphorylation of Jun 7 0.67 4.06 1.38 99.84
143 INT15921 Positive_regulation of Serpine1 85 0.68 81.24 13.4 99.84
144 INT375 Positive_regulation of REN 293 0.70 152.46 47.55 99.84
145 INT114093 Regulation of Cish 4 0.20 1.77 0.42 99.84
146 INT1308 Localization of Pomc 457 0.81 66.83 217.5 99.84
147 INT5505 Regulation of Localization of Pomc 54 0.61 6.96 30.77 99.84
148 INT45840 Positive_regulation of Gene_expression of Ptgs1 35 0.50 16.07 20.49 99.84
149 INT11859 Positive_regulation of Tbxa2r 44 0.61 22.62 9.61 99.84
150 INT15916 Positive_regulation of Ptgis 11 0.39 6.6 1.74 99.84
151 INT268758 Regulation of Positive_regulation of Mip 1 0.44 0.83 0.18 99.84
152 INT268764 Regulation of Positive_regulation of Ccr1 1 0.45 0.83 0.18 99.84
153 INT4022 Negative_regulation of PLA2G1B 30 0.59 10.41 7.58 99.84
154 INT228195 Negative_regulation of Gene_expression of Tlr2 14 0.40 12.17 1.74 99.84
155 INT9326 Regulation of Igfbp2 4 0.61 0.99 0.29 99.84
156 INT70756 Gene_expression of Adm 28 0.77 13.33 4.22 99.84
157 INT71561 Positive_regulation of Gene_expression of Adm 4 0.61 2.67 0.43 99.84
158 INT224149 Negative_regulation of Trem1 2 0.37 3.44 0.56 99.84
159 INT25076 Negative_regulation of Gene_expression of Il1 41 0.52 30.58 13.85 99.84
160 INT96074 Negative_regulation of Gene_expression of Casp1 4 0.57 2.77 0.87 99.84
161 INT82155 Negative_regulation of Uqcrc2 5 0.21 1.28 0.82 99.84
162 INT152680 Negative_regulation of THBD 3 0.29 1.87 0.21 99.84
163 INT69440 Gene_expression of ROS1 752 0.78 477.64 103.83 99.82
164 INT3657 Gene_expression of Ins1 514 0.78 321.69 75.76 99.82
165 INT74563 Positive_regulation of Gene_expression of ROS1 258 0.61 168.18 34.08 99.82
166 INT23177 Negative_regulation of Gene_expression of HLA-DRA 50 0.44 16.99 10.55 99.82
167 INT56084 Negative_regulation of SLC43A3 11 0.39 5.39 2.27 99.82
168 INT3760 Positive_regulation of ALB 142 0.70 87.46 26.7 99.82
169 INT66424 Regulation of SLC43A3 7 0.32 2.33 2.33 99.82
170 INT200554 Positive_regulation of Aliq1 29 0.22 33.02 5.32 99.80
171 INT164366 Localization of NLRP1 26 0.71 5.9 16.54 99.80
172 INT257812 Negative_regulation of Positive_regulation of Paf 1 0.03 2.08 0.17 99.80
173 INT49439 Gene_expression of Cpox 508 0.73 326.97 130.17 99.80
174 INT69993 Positive_regulation of Gene_expression of Cpox 93 0.55 69.4 22.05 99.80
175 INT190520 Negative_regulation of Hmgb1 24 0.53 20.08 5.6 99.78
176 INT5116 Gene_expression of IL2 670 0.78 291.13 146.69 99.78
177 INT73990 Positive_regulation of Gene_expression of Hspa1b 19 0.70 13.94 3.03 99.78
178 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 99.76
179 INT9158 Gene_expression of Tnf 722 0.78 522.01 277.68 99.76
180 INT82082 Localization of Lep 63 0.81 26.41 8.56 99.76
181 INT86361 Positive_regulation of Positive_regulation of NOS1 39 0.53 18.93 10.42 99.76
182 INT37405 Positive_regulation of Cst7 7 0.49 3.32 2.99 99.76
183 INT111998 Positive_regulation of Positive_regulation of Mapk8 23 0.69 9.33 8.97 99.76
184 INT95514 Negative_regulation of Ghr 3 0.36 1.3 0.99 99.76
185 INT348772 Positive_regulation of Positive_regulation of Tlr4 1 0.61 0.72 0.21 99.76
186 INT104263 Regulation of Positive_regulation of NOS1 5 0.28 3.15 2.15 99.76
187 INT11746 Positive_regulation of Il1a 65 0.63 42.94 23.54 99.76
188 INT11047 Positive_regulation of Positive_regulation of IL6 45 0.66 28.7 9.37 99.76
189 INT64636 Positive_regulation of Gene_expression of Nos2 242 0.70 147.52 79.53 99.74
190 INT18677 Gene_expression of F3 50 0.65 30.86 5.86 99.74
191 INT12598 Binding of DBP 20 0.48 13.11 3.62 99.74
192 INT73992 Gene_expression of Hspa1b 41 0.78 37.26 6.88 99.72
193 INT64346 Positive_regulation of S100B 95 0.70 63.11 9.17 99.72
194 INT70048 Positive_regulation of Gene_expression of IL10 90 0.55 71.34 25.66 99.72
195 INT85418 Positive_regulation of Gene_expression of IL9 11 0.38 11.47 9.56 99.72
196 INT3803 Negative_regulation of Igf1 45 0.58 15.95 7.98 99.72
197 INT117518 Transcription of Ccl2 12 0.68 11.12 3.61 99.72
198 INT47390 Negative_regulation of Paf 18 0.58 14.81 9.66 99.72
199 INT50196 Transcription of Il1b 25 0.69 19.08 10.43 99.72
200 INT66755 Transcription of Tnf 45 0.72 37.1 19.11 99.72
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