D:Seronegative Spondarthritis

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Disease Term
Synonyms ANKYLOSING SPONDYLITIS, Asymmetrical Inflammatory Oligoarthritis, ATHRITIS ASSOCIATED WITH INFLAMMATORY BOWEL DISEASE, Athritis Mutilans, Bamboo Spine, Enteropathic Arthritis, Hla B27, Predominant Distal Interphalangeal Joint, Psoriatic Arthritis, Psoriatic Arthropathy, PSORIATIC SPONDYLITIS
Documents 1600
Hot Single Events 200
Hot Interactions 65

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Seronegative Spondarthritis. They are ordered first by their relevance to Seronegative Spondarthritis and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT152035 Binding of HLA-A and MRAP 2 0.31 6.95 3.4 100.00
2 INT172047 Binding of HLA-A and LRRC23 1 0.22 3.32 1.64 100.00
3 INT203044 Binding of PDCD1 and DTHD1 1 0.02 3.19 1.87 100.00
4 INT333499 Binding of IGHE and PHB2 1 0.14 4.08 0.95 100.00
5 INT55837 Binding of HLA-B and PHB2 3 0.20 3.52 1.37 100.00
6 INT271511 Binding of Phb2 and Glrb 1 0.04 1.7 0.84 100.00
7 INT137897 Binding of SERPINH1 and IL36B 1 0.00 0.64 0.55 100.00
8 INT79151 Binding of HLA-B and OLAH 1 0.01 0.79 0.44 100.00
9 INT48848 Binding of HLA-B and HLA-E 3 0.34 1.95 0.45 100.00
10 INT168416 MIR146A Regulation of Irak1 1 0.24 0.99 0.59 99.80
11 INT2993 Binding of HLA-B and SUGT1 1 0.00 0.6 0.1 99.76
12 INT340440 Binding of HLA-B and BTG3 1 0.05 1.57 0.47 99.68
13 INT7656 Binding of SST and Gs 1 0.02 0.27 0.46 99.60
14 INT186128 Binding of CD2 and CD58 8 0.10 7.59 2.76 99.48
15 INT197051 Binding of HLA-E and ATP8A1 1 0.00 6.52 1.14 99.48
16 INT201940 Binding of IL8 and CXCL10 2 0.28 2.46 1.86 99.36
17 INT122096 Binding of HLA-B and SFTPA1 2 0.04 1.81 0.6 99.30
18 INT122097 Binding of LSP1 and SFTPA1 1 0.00 0.56 0.2 99.30
19 INT186125 Negative_regulation of Binding of CD2 and CD58 3 0.12 3.04 1.06 98.88
20 INT107596 Binding of PPA1 and OPLL 1 0.00 1.13 0.77 98.64
21 INT172082 TNF Regulation of SFTPA1 1 0.05 0.85 0.5 98.28
22 INT107602 Binding of OPLL and Enpp1 1 0.15 1.12 0.76 97.96
23 INT79150 HLA-B Positive_regulation of OLAH 1 0.02 0.77 0.43 97.84
24 INT340439 Binding of HLA-DMA and SUGT1 1 0.00 4.1 1.16 96.64
25 INT155009 IL23A Positive_regulation of Gene_expression of IL17A 2 0.17 0.62 0.39 96.16
26 INT182124 Binding of IRF6 and TLR4 14 0.10 16.11 4.65 96.12
27 INT188572 CD14 Regulation of Gene_expression of CD28 1 0.11 0.6 0.4 96.04
28 INT131156 Binding of RUNX1 and TNF 2 0.03 3.44 1.42 95.92
29 INT197050 Binding of HLA-DOA and HLA-E 2 0.08 1.73 0.58 95.76
30 INT119108 Binding of LTBR and TNF 2 0.15 1.47 1.07 95.76
31 INT119107 Negative_regulation of Binding of LTBR and TNF 1 0.17 1.16 0.68 95.76
32 INT172048 Binding of TNF and MICA 1 0.29 1.63 0.62 95.08
33 INT264324 Olr614 Regulation of IL-17 1 0.02 2.3 1.03 94.96
34 INT119105 Binding of FCGR1A and TNF 1 0.03 1.16 0.67 94.68
35 INT119106 Negative_regulation of Binding of FCGR1A and TNF 1 0.03 1.16 0.67 94.68
36 INT98565 HLA-B Positive_regulation of Cd8a 1 0.03 0.63 0.14 94.32
37 INT188544 ETV5 Negative_regulation of Binding of IRF6 and TLR4 1 0.00 0.59 0.38 93.92
38 INT188560 Negative_regulation of Binding of IRF6 and TLR4 1 0.04 0.58 0.38 93.92
39 INT186123 Binding of GIF and IL10 1 0.23 1.17 0.69 93.76
40 INT188567 IRF6 Positive_regulation of Gene_expression of CD28 1 0.05 1.28 0.82 93.44
41 INT207391 Il17a Positive_regulation of Gene_expression of Tnfsf11 2 0.05 1.19 0.77 92.64
42 INT207396 IL6 Positive_regulation of Gene_expression of Tnfsf11 1 0.03 0.95 0.51 92.64
43 INT207394 IL1B Positive_regulation of Gene_expression of Tnfsf11 1 0.05 0.95 0.51 92.64
44 INT264332 Olr614 Negative_regulation of Regulation of Igh-6 1 0.01 1.04 0.48 88.64
45 INT102130 Il6 Positive_regulation of Gene_expression of Crp 4 0.05 7.39 1.91 87.88
46 INT188805 TNF Positive_regulation of Gene_expression of Crp 1 0.15 2.96 0.95 87.88
47 INT188803 Il1 Positive_regulation of Gene_expression of Crp 1 0.03 2.95 0.94 87.88
48 INT186126 Binding of CD28 and CTLA4 9 0.52 4.13 3.12 87.80
49 INT149117 Binding of CD80 and CTLA4 31 0.52 12.7 7.73 87.80
50 INT186127 CTLA4 Negative_regulation of CD28 1 0.19 0.74 0.32 87.80
51 INT188563 TLR4 Positive_regulation of Gene_expression of PRF1 1 0.03 0.78 0.36 86.88
52 INT340437 Binding of SERPINH1 and HLA-DRB4 1 0.00 2.26 0.84 86.72
53 INT254347 FASLG Negative_regulation of Gene_expression of CHI3L1 1 0.13 0.92 0.42 85.68
54 INT254350 FASLG Negative_regulation of Gene_expression of VEGFA 1 0.06 0.92 0.42 85.68
55 INT311997 Regulation of STAM Regulation of BGLAP 1 0.00 0.61 0.32 84.20
56 INT346133 RAMP2 Regulation of ADM 1 0.13 2.06 0.78 83.96
57 INT207395 TNF Regulation of Gene_expression of Tnfsf11 1 0.11 0.91 0.49 83.60
58 INT311991 STAM Regulation of BGLAP 1 0.00 0.61 0.31 83.56
59 INT264555 IL15 Positive_regulation of Gene_expression of BCL2 1 0.02 0.92 0.35 82.56
60 INT168256 Binding of MLL and TNFRSF1B 1 0.00 1.2 0.53 82.32
61 INT279361 Binding of TNF and KLF1 4 0.00 3.72 2.19 81.84
62 INT279359 Binding of ADA and TNF 1 0.20 2.61 1.91 81.84
63 INT188565 IRF6 Regulation of Gene_expression of CD28 1 0.03 0.7 0.43 81.24
64 INT188562 IRF6 Regulation of Gene_expression of PRF1 1 0.01 0.7 0.43 81.24
65 INT171874 Binding of SQLE and MRAP 1 0.00 1.29 0.35 80.32
66 INT306745 Binding of Il12a and IL23A 1 0.10 3.25 1.56 79.28
67 INT211129 Negative_regulation of Binding of P4HB and TNF 1 0.10 0.97 0.9 78.36
68 INT211128 Binding of P4HB and TNF 1 0.09 0.97 0.9 77.84
69 INT19645 Binding of HLA-B and KLRD1 1 0.00 0.73 0.15 77.84
70 INT150393 Binding of CASP1 and MEFV 2 0.16 2.48 0.45 77.36
71 INT137162 IFNG Positive_regulation of Gene_expression of CXCL9 1 0.45 0.62 0.54 76.96
72 INT264326 IL-17 Positive_regulation of Gene_expression of Il6 1 0.13 0.83 0.43 76.80
73 INT334879 CASP1 Regulation of IL1B 1 0.03 1.63 0.31 76.16
74 INT183269 Binding of CEBPB and CPOX 1 0.07 1.61 0.89 76.04
75 INT137157 TNF Positive_regulation of Gene_expression of CXCL9 1 0.38 0.61 0.54 75.76
76 INT62299 Binding of CD4 and SGCG 1 0.39 1.23 0.51 75.40
77 INT328205 Binding of PSG5 and PSORS4 1 0.01 0.5 0.25 75.00
78 INT328204 Binding of DSG3 and PSORS4 1 0.00 0.5 0.25 75.00
79 INT248244 Binding of IL8 and SDC2 1 0.02 1.57 0.72 73.84
80 INT288266 Binding of AFA and CRYGD 1 0.08 1.85 0.64 72.96
81 INT201950 IFNA1 Positive_regulation of Binding of DPP4 1 0.12 2.17 1.47 72.80
82 INT201946 IFNA1 Positive_regulation of DPP4 1 0.17 2.16 1.46 72.80
83 INT201941 IFNA1 Positive_regulation of Gene_expression of CXCL10 1 0.14 1.09 0.74 72.80
84 INT201947 IFNA1 Positive_regulation of Gene_expression of DPP4 1 0.11 1.09 0.74 72.80
85 INT293704 Binding of TNF and DDX41 1 0.00 1.01 0.61 71.52
86 INT139404 Binding of TNF and SFTPA1 1 0.00 0.51 0.1 71.12
87 INT34727 TNF Positive_regulation of Gene_expression of IL2 1 0.56 0.81 0.31 70.72
88 INT248259 Binding of HSPG2 and Gtf3a 1 0.00 0.33 0.12 70.20
89 INT202020 Binding of TYROBP and NCR1 1 0.01 0.36 0.09 68.88
90 INT240730 Binding of CRYGD and MTRF1 4 0.03 4.18 1.39 68.24
91 INT248239 Binding of FN1 and SDC3 1 0.00 0.77 0.42 66.32
92 INT248243 Binding of COL7A1 and SDC3 1 0.00 0.76 0.41 66.32
93 INT248242 Binding of COL7A1 and SDC1 1 0.00 0.76 0.41 65.72
94 INT248236 Binding of FN1 and SDC1 1 0.00 0.76 0.41 65.72
95 INT340438 Binding of HLA-DMA and MRAP 1 0.02 1.69 0.43 65.12
96 INT288263 Binding of AFA and MTRF1 1 0.02 1.28 0.49 64.32
97 INT175329 Binding of ICAM1 and ITGAL 14 0.18 10.06 2.81 62.72
98 INT311990 FCGR3B Regulation of STAM 1 0.01 0.27 0.09 62.28
99 INT334061 Negative_regulation of Binding of TNFRSF11A and Tnfsf11 1 0.01 0.52 0.08 60.44
100 INT295005 Binding of TNFRSF11A and Tnfsf11 3 0.20 2.02 0.09 60.08
101 INT329801 Binding of CAMP and IFNA1 1 0.03 1.48 0.4 60.00
102 INT320121 Binding of PTEN and TNF 1 0.05 0.76 0.49 59.52
103 INT203040 Binding of PDCD1 and PDCD1LG2 3 0.40 4.86 0.98 57.80
104 INT203056 Binding of Cd274 and PDCD1LG2 1 0.13 1.61 0.57 57.80
105 INT203041 Binding of CD274 and PDCD1LG2 1 0.03 1.61 0.57 57.80
106 INT203046 Binding of PDCD1 and CD274 2 0.40 3.97 0.68 57.80
107 INT203055 Binding of PDCD1 and Cd274 1 0.40 0.8 0.29 57.80
108 INT201949 CXCL10 Positive_regulation of Phosphorylation of MAPK1 1 0.15 0.79 0.55 57.44
109 INT201944 CXCL10 Positive_regulation of Phosphorylation of AKT1 1 0.09 0.79 0.55 57.44
110 INT19512 Prl Positive_regulation of Odc1 1 0.01 0.89 0.31 54.96
111 INT307765 Myoz1 Positive_regulation of Gene_expression of Il6 1 0.01 0.71 0.21 53.96
112 INT307764 Myoz1 Positive_regulation of Transcription of Il6 1 0.01 0.72 0.21 53.96
113 INT201939 CXCL10 Positive_regulation of MAPK1 1 0.11 0.72 0.52 53.92
114 INT230019 Binding of HLA-B and ERAL1 1 0.00 2.23 1.1 52.56
115 INT248238 Binding of SDC2 and SDC3 1 0.01 0.36 0.26 52.52
116 INT71176 Binding of ICAM1 and ITGB2 4 0.21 4.93 1.07 51.40
117 INT271875 IL1RN Negative_regulation of Binding of IL1B 1 0.01 1.3 1.01 50.36
118 INT188569 Binding of CD4 and TLR4 1 0.16 0.34 0.16 50.20
119 INT183924 Binding of CHI3L1 and HLA-E 1 0.08 0.9 0.39 50.00
120 INT19513 Prl Positive_regulation of IL2 1 0.41 0.8 0.27 48.08
121 INT178574 IL2RA Positive_regulation of Gene_expression of Cd3e 1 0.04 0.16 0.05 47.24
122 INT231693 Binding of IGKV2-19 and BDNF-AS 1 0.00 2.39 0.81 46.96
123 INT311994 Binding of FCGR3B and Positive_regulation of TNF 1 0.52 0 0.06 45.44
124 INT171125 Il1 Positive_regulation of Localization of TNF 1 0.00 1.22 0.41 45.36
125 INT188561 IRF6 Positive_regulation of Transcription of CD14 1 0.03 0.25 0.25 43.92
126 INT201943 Regulation of Binding of DPP4 and CXCL10 1 0.20 0.58 0.42 43.32
127 INT137168 IFNG Positive_regulation of Gene_expression of CXCR3 1 0.32 0.34 0.32 42.16
128 INT137155 Binding of TLR5 and TLR9 Positive_regulation of Gene_expression of CXCR3 1 0.32 0.34 0.32 42.16
129 INT137154 Binding of TLR7 and TLR9 Positive_regulation of Gene_expression of CXCR3 1 0.34 0.34 0.32 42.16
130 INT137156 Binding of TLR5 and TLR7 Positive_regulation of Gene_expression of CXCR3 1 0.31 0.34 0.32 42.16
131 INT137160 TLR7 Positive_regulation of Gene_expression of CXCR3 1 0.35 0.34 0.32 42.16
132 INT137158 TLR5 Positive_regulation of Gene_expression of CXCR3 1 0.32 0.34 0.32 42.16
133 INT321598 Binding of MLL and TNF 1 0.05 1.07 0.49 40.04
134 INT201942 DPP4 Negative_regulation of CXCL10 1 0.33 0.9 1.3 38.76
135 INT174508 Binding of CD4 and HLA-B 1 0.14 4.68 1.53 38.72
136 INT283980 Binding of IL12A and IL23A 2 0.24 1.33 0.57 38.32
137 INT311995 FCGR3B Regulation of Gene_expression of TNF 1 0.46 0 0.03 38.24
138 INT325028 TNF Negative_regulation of Ptgs1 1 0.00 1.79 0.23 36.56
139 INT325008 TNF Negative_regulation of Gene_expression of NOSTRIN 1 0.00 1.78 0.23 36.56
140 INT325007 TNF Negative_regulation of NOSTRIN 1 0.00 1.78 0.23 36.56
141 INT137159 Binding of TLR7 and TLR9 1 0.27 0.33 0.29 36.16
142 INT137163 Binding of TLR5 and TLR9 1 0.25 0.33 0.29 36.16
143 INT137169 Binding of TLR5 and TLR7 1 0.25 0.33 0.29 36.16
144 INT201948 Binding of DPP4 and CXCL10 1 0.27 0.54 0.39 35.00
145 INT211115 Positive_regulation of Binding of LTBR and TNF 1 0.01 0.31 0.39 34.16
146 INT293703 Binding of DDX41 and C21orf91 1 0.00 0.99 0.42 33.60
147 INT248271 IL6 Regulation of Gene_expression of Crp 3 0.27 1.7 0.73 33.00
148 INT137170 CXCL9 Positive_regulation of Binding of CXCR3 1 0.44 0.31 0.31 32.68
149 INT182348 Binding of Cd3e and Crp 1 0.15 2.33 0.56 32.64
150 INT182346 Binding of Cd3e and Esr1 1 0.06 1.26 0.25 32.64
151 INT182350 Binding of Ms4a1 and Crp 1 0.10 1.25 0.25 32.44
152 INT182349 Binding of Ms4a1 and Esr1 1 0.04 1.26 0.25 32.44
153 INT227543 Mtx1 Positive_regulation of Prep 1 0.22 1.19 1.92 30.88
154 INT227542 Mtx1 Positive_regulation of Binding of Prep 1 0.23 1.2 1.92 30.88
155 INT227545 Hspa9 Positive_regulation of Prep 1 0.18 0.59 0.96 30.24
156 INT188587 Trav6-3 Positive_regulation of Gene_expression of PRF1 1 0.00 0.21 0.11 29.24
157 INT311992 Binding of FCGR3B and STAM 1 0.02 0 0 28.24
158 INT248237 Binding of IL8 and SDC3 1 0.02 0.52 0.18 28.00
159 INT182154 Binding of HLA-DRA and DCPS 1 0.01 0.23 0.12 27.80
160 INT137167 Binding of IFNG and TLR3 1 0.24 0.32 0.27 27.44
161 INT300551 TBX21 Regulation of Hand1 2 0.10 0.44 0.48 26.76
162 INT148704 Binding of TNF and TNFRSF1A 5 0.44 3.3 2.09 26.44
163 INT288003 Binding of COL2A1 and PADI1 1 0.09 0.11 0.06 26.28
164 INT137166 IL8 Positive_regulation of CXCR2 1 0.24 0.28 0.27 25.00
165 INT252296 TNF Regulation of Gene_expression of Il1 2 0.03 1.28 0.49 22.72
166 INT252294 TNF Regulation of Gene_expression of Il6 2 0.16 1.28 0.49 22.72
167 INT307755 TNF Regulation of Gene_expression of IL8 1 0.02 0.5 0.14 22.72
168 INT307769 TNF Regulation of Gene_expression of Csf2 1 0.03 0.5 0.14 22.72
169 INT307771 TNF Negative_regulation of Gene_expression of Csf2 1 0.03 0.5 0.14 22.72
170 INT279960 TNF Positive_regulation of Vcam1 1 0.56 0.27 0.18 20.56
171 INT202015 Binding of KIR3DL1 and BW4 1 0.29 0.23 0.11 17.68
172 INT288002 Binding of COL2A1 and GOPC 1 0.12 0 0 17.12
173 INT182347 Binding of Glrb and Cd163 1 0.24 0.98 0.28 15.44
174 INT122163 Binding of TNF and TNFRSF1B 6 0.44 6.06 2.41 14.68
175 INT188564 IRF6 Positive_regulation of Gene_expression of PRF1 1 0.01 0.44 0.44 13.56
176 INT171123 TNF Positive_regulation of Localization of Spg7 1 0.01 1.35 0.46 9.12
177 INT346136 ADM Positive_regulation of ICAM1 1 0.20 0.92 0.08 5.48
178 INT346147 ADM Positive_regulation of Gene_expression of VCAM1 1 0.19 0.91 0.08 5.48
179 INT346149 ADM Positive_regulation of Gene_expression of SELE 1 0.22 0.85 0.07 5.48
180 INT188692 Binding of Cd40 and Cd40lg 32 0.34 22.95 6.62 5.00
181 INT155484 Binding of CD86 and CTLA4 15 0.52 8.85 6.09 5.00
182 INT121651 Binding of CXCL12 and CXCR4 13 0.48 17.61 3.52 5.00
183 INT194647 Binding of CD28 and CD80 15 0.40 4.9 3.22 5.00
184 INT171974 Binding of Tnfrsf11a and Tnfsf11 14 0.35 13.11 3.11 5.00
185 INT130721 Binding of IL1B and IL1RN 6 0.05 5.29 2.85 5.00
186 INT86179 TNF Positive_regulation of Localization of IL6 5 0.35 1.66 2.17 5.00
187 INT239037 Binding of Cd28 and Cd86 9 0.16 3.69 2.14 5.00
188 INT183781 Binding of IL6 and INS 6 0.22 8.97 1.87 5.00
189 INT174503 Binding of HLA-B and KIR3DL1 6 0.37 3.48 1.61 5.00
190 INT182097 Binding of Il6 and Il1 4 0.07 4.67 1.55 5.00
191 INT252633 Binding of TNF and Tnfrsf1b 4 0.05 3.66 1.54 5.00
192 INT285569 TNF Negative_regulation of Gene_expression of Il6 1 0.03 2.83 1.46 5.00
193 INT264327 IL-17 Positive_regulation of Gene_expression of Tnfsf11 1 0.07 3.19 1.33 5.00
194 INT265213 Binding of Ctla4 and Cd86 2 0.13 1.93 1.31 5.00
195 INT254355 PF4 Positive_regulation of IFNA1 1 0.04 1.23 1.26 5.00
196 INT202042 CAMK2N2 Negative_regulation of MMP9 1 0.01 0.73 1.25 5.00
197 INT202041 CAMK2N2 Negative_regulation of PPP1R11 1 0.00 0.74 1.25 5.00
198 INT202039 CAMK2N2 Negative_regulation of MMP1 1 0.00 0.73 1.24 5.00
199 INT186355 Il23a Positive_regulation of Gene_expression of Il17a 4 0.12 3 1.24 5.00
200 INT202036 CAMK2N2 Negative_regulation of MMP3 1 0.00 0.73 1.24 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Seronegative Spondarthritis. They are ordered first by their pain relevance and then by number of times they were reported in Seronegative Spondarthritis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT1878 Binding of HLA-B 440 0.48 321.16 127.36 100.00
2 INT749 Gene_expression of HLA-B 341 0.75 224.12 77.37 100.00
3 INT1876 Positive_regulation of HLA-B 82 0.69 52.16 21.08 100.00
4 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 100.00
5 INT636 Binding of MRAP 54 0.48 40.36 18.77 100.00
6 INT19330 Binding of HLA-A 99 0.48 76.26 22.85 100.00
7 INT1873 Gene_expression of MRAP 51 0.76 31.75 13.92 100.00
8 INT637 Positive_regulation of MRAP 23 0.67 21.13 9.97 100.00
9 INT106444 Binding of PHB2 4 0.48 13.74 4.07 100.00
10 INT15516 Gene_expression of Crp 711 0.77 615.33 173.09 100.00
11 INT3925 Negative_regulation of HLA-B 29 0.42 20.19 9.46 100.00
12 INT621 Positive_regulation of SERPINH1 19 0.57 21.52 8.44 100.00
13 INT67822 Binding of SERPINH1 17 0.36 19.05 7.24 100.00
14 INT106446 Positive_regulation of PHB2 3 0.66 4.38 1.62 100.00
15 INT5284 Regulation of HLA-B 25 0.59 12.91 7.74 100.00
16 INT4697 Positive_regulation of Gene_expression of HLA-B 32 0.61 17.32 5.97 100.00
17 INT11696 Gene_expression of HLA-A 50 0.78 41.25 14.1 100.00
18 INT106445 Gene_expression of PHB2 4 0.74 3.55 1.18 100.00
19 INT3055 Binding of OLAH 9 0.28 7.14 3.99 100.00
20 INT11700 Negative_regulation of Gene_expression of HLA-B 3 0.50 2.61 0.6 100.00
21 INT211203 Positive_regulation of Gene_expression of IMPACT 1 0.17 2 1.75 100.00
22 INT66423 Binding of ELOVL1 52 0.40 61.63 5.16 100.00
23 INT6513 Positive_regulation of Gene_expression of BGLAP 24 0.67 11.69 3.96 100.00
24 INT14510 Gene_expression of SOD1 208 0.76 88.56 12.4 100.00
25 INT31989 Binding of SOD1 43 0.47 19.38 2.55 100.00
26 INT137049 Positive_regulation of Glrb 7 0.46 9.24 3.22 100.00
27 INT107597 Binding of Enpp1 5 0.37 3.35 2.23 100.00
28 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 100.00
29 INT2249 Negative_regulation of Binding of HLA-B 5 0.54 6.82 2.94 100.00
30 INT18954 Negative_regulation of OLAH 9 0.09 8.31 3.67 100.00
31 INT211135 Positive_regulation of Localization of MTX1 2 0.23 2.14 2.14 100.00
32 INT18920 Binding of Egf 24 0.48 9.43 3.57 100.00
33 INT2016 Negative_regulation of MRAP 6 0.41 3.21 1.59 100.00
34 INT122951 Regulation of Binding of HLA-B 4 0.39 3.08 1.65 100.00
35 INT155015 Positive_regulation of HLA-DOA 6 0.23 4.45 1.92 100.00
36 INT41083 Regulation of OLAH 3 0.36 2.01 0.83 100.00
37 INT1115 Regulation of Positive_regulation of MRAP 1 0.45 0.44 0.25 100.00
38 INT3912 Localization of HLA-DMA 2 0.35 1.09 0.27 100.00
39 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 99.98
40 INT11325 Gene_expression of HLA-E 209 0.76 98.05 33.72 99.98
41 INT192676 Binding of PTEN 14 0.46 10.58 3.06 99.98
42 INT27551 Gene_expression of SERPINH1 45 0.62 42.87 9.04 99.98
43 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98 99.96
44 INT3839 Positive_regulation of Gene_expression of FCGR3B 10 0.67 13.58 6.25 99.92
45 INT203050 Binding of PDCD1 12 0.48 12.93 4.5 99.92
46 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210 99.92
47 INT14026 Positive_regulation of Igh-6 24 0.68 10.84 4.32 99.90
48 INT3841 Gene_expression of FCGR3B 117 0.75 58.99 28.87 99.84
49 INT9489 Gene_expression of SFTPA1 112 0.66 55.38 66.45 99.84
50 INT67849 Gene_expression of SKP1 4 0.78 2.83 1.48 99.84
51 INT153776 Positive_regulation of IL17A 42 0.64 34.58 14.82 99.84
52 INT172055 Positive_regulation of Binding of MRAP 1 0.33 1.69 0.84 99.84
53 INT62832 Negative_regulation of Gene_expression of SELE 16 0.49 10.6 5.12 99.84
54 INT5374 Gene_expression of Esr1 412 0.77 263.89 67.34 99.84
55 INT26500 Gene_expression of MMP2 201 0.78 110.57 46.9 99.84
56 INT99911 Localization of MTX1 5 0.45 3.81 3.07 99.84
57 INT9236 Regulation of Gene_expression of TNF 204 0.62 162.66 72.99 99.84
58 INT312005 Localization of SKP1 1 0.13 1.22 0.57 99.84
59 INT11380 Negative_regulation of IL1B 215 0.59 125.62 72.35 99.84
60 INT43997 Positive_regulation of Gene_expression of Esr1 57 0.51 36.66 5.51 99.84
61 INT11823 Positive_regulation of GGT1 53 0.67 45.84 7.55 99.84
62 INT287143 Regulation of SKP1 2 0.04 0.84 0.34 99.84
63 INT11331 Positive_regulation of FANCB 5 0.49 2.23 1.09 99.84
64 INT104551 Gene_expression of Il18 156 0.76 115.51 36.95 99.84
65 INT34869 Negative_regulation of PTGS2 778 0.59 366.76 319.85 99.82
66 INT183936 Binding of Ank 1 0.42 6.89 5.83 99.80
67 INT171989 Gene_expression of Ank 8 0.78 11.76 4.36 99.80
68 INT6516 Positive_regulation of BGLAP 45 0.67 26.61 9.9 99.80
69 INT132161 Gene_expression of MTX1 48 0.58 26.55 32.32 99.80
70 INT312010 Positive_regulation of Regulation of FCGR3B 1 0.45 1.04 0.77 99.80
71 INT137898 Binding of IL36B 1 0.13 0.64 0.54 99.80
72 INT55879 Gene_expression of CCL2 421 0.78 240.74 166.02 99.76
73 INT81280 Binding of Atp9a 20 0.47 11.14 3.24 99.76
74 INT8483 Positive_regulation of Positive_regulation of TNF 73 0.67 60.35 22.03 99.76
75 INT1938 Positive_regulation of DONSON 3 0.13 3.02 1.07 99.76
76 INT102941 Binding of HLA-DPA2 1 0.00 1.24 0.84 99.76
77 INT3002 Binding of SUGT1 62 0.24 55.9 14.91 99.76
78 INT183942 Binding of rs 7 0.02 8.71 0.61 99.76
79 INT183943 Binding of SPACA7 1 0.00 0.33 0.33 99.76
80 INT46637 Gene_expression of CXCL10 172 0.78 121.94 57.74 99.74
81 INT10832 Gene_expression of IL8 1050 0.78 698.72 270 99.74
82 INT64903 Positive_regulation of HLA-C 3 0.49 2.54 0.93 99.72
83 INT56160 Binding of Ifx 14 0.36 11.39 5.74 99.70
84 INT94335 Positive_regulation of CXCL10 71 0.58 50.69 23 99.68
85 INT211198 Localization of SERPINH1 2 0.66 4.33 1.25 99.68
86 INT117545 Regulation of Gene_expression of HLA-A 2 0.33 2.3 1.99 99.68
87 INT22058 Positive_regulation of Igha 7 0.49 5.29 1.69 99.68
88 INT3513 Negative_regulation of Igha 9 0.38 7.43 0.56 99.66
89 INT49196 Gene_expression of SELE 105 0.78 107.29 22.92 99.64
90 INT3830 Positive_regulation of FCGR3B 27 0.67 15.18 10.49 99.64
91 INT94454 Gene_expression of CD68 73 0.72 63.94 10.43 99.64
92 INT8775 Binding of IGHE 167 0.48 102.61 23.54 99.64
93 INT145266 Gene_expression of IL17A 154 0.75 109.83 45.33 99.62
94 INT2064 Positive_regulation of BTG3 29 0.49 25.58 15.37 99.62
95 INT34644 Binding of HLA-C 19 0.47 9.41 2.2 99.60
96 INT46405 Negative_regulation of Gene_expression of ATN1 1 0.41 2.58 0.69 99.60
97 INT46402 Negative_regulation of Gene_expression of DONSON 1 0.04 2.58 0.69 99.60
98 INT46401 Negative_regulation of ATN1 1 0.41 2.57 0.69 99.60
99 INT46410 Negative_regulation of DONSON 1 0.04 2.57 0.69 99.60
100 INT46404 Negative_regulation of NDUFA5 1 0.18 2.57 0.69 99.60
101 INT179885 Regulation of PTEN 8 0.26 11.88 2.18 99.60
102 INT13823 Gene_expression of Egf 97 0.78 39.99 12.99 99.60
103 INT248256 Localization of SDC3 1 0.14 2.46 0.94 99.60
104 INT186893 Binding of BGLAP 10 0.37 6.19 2.02 99.60
105 INT312011 Negative_regulation of Binding of BGLAP 1 0.11 1.04 0.76 99.60
106 INT122812 Gene_expression of SNRNP70 130 0.75 67 12.5 99.60
107 INT691 Binding of SST 67 0.48 24.66 32.67 99.60
108 INT9235 Negative_regulation of Gene_expression of TNF 346 0.59 252.98 118.61 99.58
109 INT82828 Positive_regulation of COMP 45 0.61 35.12 6.2 99.56
110 INT200470 Positive_regulation of Gene_expression of COMP 13 0.69 13.73 2.93 99.56
111 INT10838 Positive_regulation of IL8 381 0.70 295.51 101.62 99.56
112 INT87470 Gene_expression of SDC1 27 0.78 24.86 5.81 99.56
113 INT27651 Gene_expression of S100A12 45 0.76 52.25 10.51 99.54
114 INT312007 Positive_regulation of SKP1 1 0.13 2.37 1.24 99.54
115 INT81722 Regulation of Gene_expression of FCGR3B 5 0.44 3.42 2.47 99.52
116 INT3353 Localization of HLA-B 25 0.75 16.05 8.62 99.50
117 INT183937 Positive_regulation of Ank 3 0.50 3.39 1.81 99.50
118 INT3838 Regulation of FCGR3B 16 0.60 6.67 5.53 99.50
119 INT6481 Binding of TNF 624 0.48 510.2 214.82 99.48
120 INT11699 Binding of HLA-E 85 0.47 52.51 13.41 99.48
121 INT107599 Negative_regulation of Enpp1 8 0.51 6.02 1.24 99.48
122 INT6852 Localization of TNF 883 0.81 705.95 270.84 99.44
123 INT15515 Positive_regulation of Crp 700 0.70 604.24 150.15 99.44
124 INT306739 Positive_regulation of Gene_expression of IL22 2 0.28 2.2 1.36 99.44
125 INT246031 Gene_expression of IL22 10 0.40 9.48 5.11 99.44
126 INT86705 Gene_expression of BTG3 41 0.65 37.29 8.29 99.44
127 INT48232 Gene_expression of MMP1 245 0.78 96.31 57.72 99.44
128 INT112970 Regulation of Ccr1 8 0.29 7.77 1.93 99.42
129 INT76860 Gene_expression of HSPG2 32 0.65 37.14 9.06 99.40
130 INT203048 Gene_expression of PDCD1 13 0.78 8.5 2.62 99.40
131 INT117220 Positive_regulation of TLR4 64 0.69 53.61 17.33 99.40
132 INT55838 Gene_expression of RPL21P109 1 0.02 0.8 0.57 99.40
133 INT82829 Gene_expression of COMP 104 0.78 57 9.81 99.38
134 INT203049 Negative_regulation of PDCD1 6 0.43 7.15 2.36 99.38
135 INT97131 Positive_regulation of CD14 25 0.67 12.03 4.21 99.36
136 INT63349 Gene_expression of PECAM1 199 0.75 166.03 36.76 99.32
137 INT9256 Gene_expression of SELPLG 30 0.75 16.44 3.66 99.32
138 INT134646 Gene_expression of Tnfsf11 19 0.69 14.77 4.16 99.30
139 INT133028 Gene_expression of TLR2 209 0.73 131.92 36.17 99.30
140 INT117223 Gene_expression of TLR4 348 0.78 206.18 54.42 99.30
141 INT161840 Gene_expression of Tnfrsf11b 17 0.78 12.44 2.63 99.28
142 INT16322 Gene_expression of Il2rb 19 0.51 15.88 12.18 99.28
143 INT166467 Negative_regulation of Gene_expression of Tnfrsf11b 6 0.50 5.5 2.04 99.28
144 INT11388 Positive_regulation of PMEL 11 0.67 5.9 2.09 99.28
145 INT169180 Binding of SNRNP70 204 0.47 119.1 29.3 99.28
146 INT3375 Gene_expression of IGHE 535 0.77 387.47 65.46 99.26
147 INT34585 Negative_regulation of Positive_regulation of HSD11B1 31 0.57 43.54 2.47 99.22
148 INT170182 Negative_regulation of SULT2A1 14 0.34 11.47 3.63 99.20
149 INT203052 Regulation of PDCD1 1 0.39 0.79 0.45 99.20
150 INT137175 Positive_regulation of Gene_expression of CXCL9 1 0.47 1.32 1.07 99.18
151 INT137179 Positive_regulation of CXCL9 11 0.65 7.73 5.11 99.18
152 INT137183 Positive_regulation of Gene_expression of CXCL11 3 0.45 2.38 0.7 99.18
153 INT182338 Gene_expression of Glrb 11 0.51 14.26 5.1 99.16
154 INT96273 Binding of TAP1 4 0.37 4.27 2.67 99.14
155 INT29496 Gene_expression of MMP3 136 0.75 49.49 41.78 99.12
156 INT12891 Negative_regulation of MMP3 41 0.58 17.99 15.06 99.12
157 INT328210 Positive_regulation of Negative_regulation of LCE3B 1 0.45 0.65 0.33 99.12
158 INT73502 Positive_regulation of IL10 154 0.69 124.87 43.5 99.12
159 INT85245 Positive_regulation of PID1 2 0.16 2.55 0.29 99.12
160 INT17612 Gene_expression of CRP 676 0.78 580.61 119.03 99.10
161 INT84911 Gene_expression of SUGT1 43 0.11 19.85 4.54 99.08
162 INT183131 Gene_expression of GPC1 3 0.08 3.68 0.95 99.08
163 INT83745 Gene_expression of SULT2A1 34 0.59 15.96 6.66 99.04
164 INT3361 Positive_regulation of Esr1 273 0.69 208.53 44.81 99.04
165 INT53574 Regulation of Tnf 45 0.62 40.68 19.71 99.04
166 INT6515 Gene_expression of BGLAP 110 0.75 45.13 10.81 99.00
167 INT248253 Positive_regulation of Gene_expression of HSPG2 3 0.44 4.61 1.65 99.00
168 INT137181 Gene_expression of CXCL9 25 0.65 13.09 9.56 99.00
169 INT227523 Localization of Hspa9 9 0.60 5.26 3.18 99.00
170 INT119838 Positive_regulation of PTEN 25 0.67 21.71 2.5 98.96
171 INT137847 Negative_regulation of Tnfsf11 4 0.42 1.31 0.24 98.96
172 INT20205 Binding of IgG 108 0.46 66.68 8.57 98.88
173 INT155130 Gene_expression of IMPACT 14 0.58 3.43 1.61 98.88
174 INT10837 Positive_regulation of Gene_expression of IL8 294 0.70 190.08 70.34 98.88
175 INT64653 Binding of CD2 17 0.44 6.74 4.45 98.88
176 INT131161 Binding of CD58 5 0.17 3.54 1.03 98.88
177 INT186136 Negative_regulation of Binding of CD2 2 0.29 2.06 0.68 98.88
178 INT131160 Negative_regulation of Binding of CD58 2 0.15 1.83 0.53 98.88
179 INT125885 Positive_regulation of Gene_expression of CHI3L1 8 0.49 10.8 2.64 98.88
180 INT16303 Negative_regulation of Localization of GH1 89 0.59 37.31 22.15 98.88
181 INT252 Localization of GH1 529 0.80 227.4 122.05 98.88
182 INT174558 Regulation of KIR2DS2 1 0.20 1.38 0.45 98.88
183 INT5328 Positive_regulation of CD4 191 0.69 133.43 21.31 98.84
184 INT191125 Gene_expression of Igfals 12 0.25 12.96 2.89 98.82
185 INT9660 Regulation of TNF 363 0.62 312.94 139.99 98.80
186 INT6477 Gene_expression of IL1RN 213 0.77 114.69 58.62 98.80
187 INT109910 Gene_expression of CCL16 104 0.74 76.1 43.97 98.80
188 INT182342 Regulation of Gene_expression of Glrb 1 0.34 1.12 0.63 98.80
189 INT8640 Positive_regulation of HSD11B1 332 0.67 377.84 22.36 98.78
190 INT85015 Gene_expression of ADM 29 0.73 30.75 10.21 98.76
191 INT141969 Positive_regulation of Gene_expression of ADM 4 0.57 4.07 1.2 98.76
192 INT15514 Negative_regulation of Crp 275 0.59 194.6 64.86 98.74
193 INT38056 Localization of Crp 71 0.78 53.14 17.03 98.74
194 INT172054 Binding of PDLIM7 1 0.17 1.29 0.59 98.72
195 INT7653 Regulation of Gs 3 0.21 1.87 0.87 98.72
196 INT91333 Gene_expression of CXCL11 11 0.65 10.96 4.1 98.70
197 INT81989 Positive_regulation of Tnfsf11 11 0.54 7.57 2.4 98.68
198 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 98.68
199 INT230758 Positive_regulation of Gene_expression of PTPRC 11 0.49 6.04 2.45 98.68
200 INT11051 Positive_regulation of Gene_expression of IL6 415 0.69 319.21 109.3 98.68
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