D:Severe Combined Immunodeficiency

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Disease Term
Synonyms Bare Lymphocyte Syndrome, Bls Bare Lymphocyte Syndrome, Combined T Cell B Cell Immunodeficiency, SCID, SCID DUE TO ABSENT CLASS II HLA ANTIGENS, Scid Severe Combined Immunodeficiency, Severe Combined Immunodeficiency Disease, Severe Combined Immunodeficiency Syndrome, Severe Combined Immunologic Deficiency
Documents 436
Hot Single Events 200
Hot Interactions 22

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Severe Combined Immunodeficiency. They are ordered first by their relevance to Severe Combined Immunodeficiency and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT176479 IL17A Positive_regulation of Gene_expression of TIMP1 1 0.02 1.33 0.74 99.68
2 INT191059 Bcl2 Positive_regulation of Localization of Il12a 1 0.16 0.77 0 98.80
3 INT224701 Timp3 Negative_regulation of TNF 1 0.01 0.65 0.34 98.24
4 INT199863 Gopc Negative_regulation of Jun 1 0.03 1.07 0 96.40
5 INT199858 Gopc Negative_regulation of Phosphorylation of Jun 1 0.03 1.08 0 96.40
6 INT199860 Gopc Negative_regulation of Positive_regulation of Mapk8 1 0.07 1.07 0 96.40
7 INT192158 Binding of Mmp2 and Mmp9 1 0.21 0.94 0.83 95.58
8 INT199862 Mapk8 Negative_regulation of Jun 1 0.05 1.06 0 94.48
9 INT258338 Binding of Aicda and Cr2 1 0.24 1.35 0.51 94.00
10 INT228499 Binding of FAS and Fasl 1 0.15 2.75 0.73 93.28
11 INT310136 Binding of Cd34 and Ccl21a 1 0.06 0.28 0 92.88
12 INT282555 POU5F1 Positive_regulation of Positive_regulation of MAPK1 1 0.11 0.28 0.04 90.28
13 INT314055 THL Negative_regulation of Localization of VEGFA 1 0.04 3.73 0.11 90.08
14 INT171123 TNF Positive_regulation of Localization of Spg7 1 0.01 1.35 0.46 89.60
15 INT282540 STAT3 Positive_regulation of Positive_regulation of MAPK1 1 0.04 0.27 0.04 89.60
16 INT285385 Ass1 Positive_regulation of Transcription of Cyp1a2 1 0.00 0.09 0.03 87.04
17 INT328224 Col2a1 Positive_regulation of Gene_expression of Mmp13 1 0.04 0.8 0.29 84.48
18 INT129594 St13 Positive_regulation of Positive_regulation of Tnf 1 0.26 0.85 0.21 84.48
19 INT129592 St13 Positive_regulation of Protein_catabolism of Stat3 1 0.26 0.84 0.16 84.48
20 INT129593 St13 Positive_regulation of Positive_regulation of Stat3 1 0.28 0.84 0.16 84.48
21 INT228494 Binding of Ncoa5 and Rela 1 0.00 1.58 0.72 84.20
22 INT225268 Negative_regulation of S100a7a Negative_regulation of Gene_expression of VEGFA 1 0.01 0.24 0 82.00
23 INT245110 Binding of MMP9 and Mmp9 1 0.08 1.53 0 79.64
24 INT219253 Binding of Cd79a and Pigr 2 0.22 0.67 0.52 78.96
25 INT224678 Binding of Mmp14 and Mmp23 1 0.00 0.85 0.69 78.80
26 INT171974 Binding of Tnfrsf11a and Tnfsf11 14 0.35 13.11 3.11 78.36
27 INT285384 Binding of Rare1 and Rxra 1 0.01 0.08 0.05 78.20
28 INT314042 THL Negative_regulation of Gene_expression of Mmp2 1 0.19 2.97 0.42 77.88
29 INT314049 THL Negative_regulation of Gene_expression of Plau 1 0.20 2.91 0.19 77.88
30 INT314048 THL Negative_regulation of Gene_expression of Gopc 1 0.09 1.05 0.05 77.88
31 INT219257 Binding of Cd79a and G2e3 1 0.01 0.08 0 77.68
32 INT192161 Mmp14 Positive_regulation of Mmp2 2 0.19 1.23 1.81 77.48
33 INT237151 Binding of Klrk1 and Ulbp1 1 0.05 1.02 0.05 76.68
34 INT237149 Binding of H60a and Klrk1 1 0.24 1.01 0.05 76.68
35 INT237150 Binding of Klrk1 and Rae1 1 0.04 1.14 0.05 76.68
36 INT284556 Tspan7 Positive_regulation of Mthfd1 1 0.00 1.66 0 75.80
37 INT225267 Gene_expression of S100a7a Positive_regulation of Gene_expression of VEGFA 1 0.01 0.23 0 75.76
38 INT288134 Pdgfa Regulation of Ifi35 1 0.01 0.78 0.03 75.68
39 INT288138 VEGFA Regulation of Ifi35 1 0.00 0.78 0.03 75.68
40 INT228500 Fadd Positive_regulation of FAS 1 0.14 1.12 0.28 75.08
41 INT176473 IL10 Positive_regulation of Gene_expression of PECAM1 1 0.05 1.1 0.75 75.04
42 INT258344 Scara3 Positive_regulation of Gene_expression of Aicda 1 0.07 0.5 0.12 75.04
43 INT258342 Scara3 Positive_regulation of Cr2 1 0.05 0.52 0.12 75.04
44 INT225265 Gene_expression of S100a7a Positive_regulation of VEGFA 1 0.01 0.23 0 74.88
45 INT224702 Timp2 Positive_regulation of Binding of Mmp14 and Mmp9 1 0.00 0.81 0.65 74.64
46 INT224693 Timp2 Positive_regulation of Binding of Mmp9 1 0.01 0.81 0.65 74.64
47 INT224683 Mmp14 Positive_regulation of Binding of Mmp9 1 0.01 0.81 0.65 74.36
48 INT224684 Binding of Mmp14 and Mmp9 1 0.01 0.81 0.64 73.84
49 INT205152 Binding of CD44 and MMP9 23 0.35 17.13 1.85 73.36
50 INT205155 Negative_regulation of Binding of CD44 and MMP9 1 0.32 1.98 0.23 73.36
51 INT224688 Pten Regulation of Akt1 1 0.04 1.12 0.19 72.68
52 INT327404 Binding of Xiap and Siva1 1 0.02 1.97 0.03 71.36
53 INT289711 Binding of F2 and Spp1 1 0.08 0.21 0.08 71.12
54 INT171125 Il1 Positive_regulation of Localization of TNF 1 0.00 1.22 0.41 70.56
55 INT205611 Gm6668 Negative_regulation of Fgfr1 1 0.01 1.59 0 69.84
56 INT205612 Gm6668 Negative_regulation of Pdgfrb 1 0.00 1.57 0 69.04
57 INT205614 Gm6668 Negative_regulation of Kdr 1 0.01 1.5 0 68.16
58 INT314041 THL Negative_regulation of Gene_expression of Mmp9 1 0.13 1.86 0.14 68.08
59 INT224680 Tgfb1 Negative_regulation of Pten 1 0.00 1.19 0.18 67.76
60 INT213365 AR Regulation of Gene_expression of VEGFA 1 0.09 1.52 0 67.68
61 INT224674 S100a4 Positive_regulation of Gene_expression of Mmp9 1 0.03 0.85 0.45 67.60
62 INT224686 S100a4 Positive_regulation of Gene_expression of Mmp13 1 0.05 0.85 0.45 67.60
63 INT224692 S100a4 Positive_regulation of Gene_expression of Mmp1a 1 0.02 0.85 0.45 67.60
64 INT205613 Gm6668 Negative_regulation of Akt1 1 0.00 0.94 0 67.36
65 INT282561 POU5F1 Positive_regulation of Gene_expression of NANOG 1 0.11 0.26 0.04 66.24
66 INT314772 Binding of Egf and Gast 1 0.02 0.62 0 65.60
67 INT314774 Binding of Gast and Glp1r 1 0.01 0.62 0 65.60
68 INT314011 VEGFA Regulation of IL19 1 0.04 1.11 0.08 64.64
69 INT224700 TNF Positive_regulation of Angpt1 1 0.00 0.63 0.34 63.60
70 INT316748 IL18 Positive_regulation of Regulation of Hand2 1 0.14 1.11 0.18 61.88
71 INT171126 Lta Positive_regulation of NOSTRIN 1 0.01 0.76 0.24 60.72
72 INT171124 Spg7 Positive_regulation of NOSTRIN 1 0.01 0.76 0.24 60.72
73 INT187222 Binding of Vip and Vipr2 2 0.19 1.82 0.56 60.28
74 INT318378 Binding of Uevld and Vmn1r7 1 0.02 0.92 0 59.72
75 INT224675 S100a4 Positive_regulation of Mmp3 1 0.04 0.94 0.48 59.20
76 INT285388 Ahr Positive_regulation of Gene_expression of Cyp27b1 1 0.01 0.14 0.04 58.84
77 INT285386 Ahr Positive_regulation of Binding of Cyp27b1 1 0.01 0.14 0.04 58.84
78 INT314043 THL Negative_regulation of Mmp2 1 0.22 2.11 0.53 58.52
79 INT314039 THL Negative_regulation of Binding of Mmp2 1 0.16 1.62 0.14 58.52
80 INT274471 IL12A Negative_regulation of Gene_expression of IL10 1 0.02 0.99 0.1 58.12
81 INT254360 Binding of EPAS1 and HIF1A 3 0.39 3.36 0.46 56.84
82 INT88778 Binding of Oprm1 and Pomc 3 0.21 0.56 1.14 56.36
83 INT138428 Binding of Oprm1 and Pomc Positive_regulation of Gene_expression of Pomc 1 0.30 0.38 0.7 56.36
84 INT316713 Binding of Ddx41 and Pain1 1 0.00 0.94 0.28 56.08
85 INT228501 Binding of AAVS1 and Fgfr1 1 0.01 0.57 0.07 54.00
86 INT245111 MMP9 Positive_regulation of Localization of Gtf3a 1 0.00 0.99 0 53.60
87 INT199859 Gem Positive_regulation of Phosphorylation of Mapk8 1 0.10 0.67 0 52.08
88 INT203149 Binding of Mif and Osm 1 0.02 2.93 1.78 51.36
89 INT277355 VEGFA Regulation of Trerf1 1 0.08 1.17 0.37 51.20
90 INT277352 Gene_expression of VEGFA Regulation of Trerf1 1 0.08 1.16 0.37 51.20
91 INT327749 Binding of KITLG and Il6 1 0.00 0.05 0.08 50.68
92 INT315969 Binding of Lipg and Msc 1 0.01 0.14 0.06 50.00
93 INT277353 VEGFA Regulation of Mtor 1 0.02 1.11 0.37 49.60
94 INT277354 Gene_expression of VEGFA Regulation of Mtor 1 0.02 1.1 0.37 49.60
95 INT243626 Twist1 Regulation of Hand1 1 0.15 1.55 0.72 49.44
96 INT224679 Il18 Positive_regulation of Gene_expression of Vcam1 1 0.01 0.41 0.05 48.88
97 INT314056 THL Negative_regulation of VEGFA 1 0.03 0.85 0.06 47.44
98 INT314036 Mapk3 Positive_regulation of Binding of VEGFA and Sp1 1 0.01 1.32 0.03 45.96
99 INT271646 VCAN Regulation of Gene_expression of FN1 1 0.06 0.15 0 45.00
100 INT271647 GFAP Regulation of Gene_expression of FN1 1 0.03 0.15 0 45.00
101 INT271650 GFAP Regulation of Gene_expression of VCAN 1 0.23 0.15 0 45.00
102 INT271644 VCAN Regulation of Gene_expression of CSPG4 1 0.38 0.15 0 45.00
103 INT271645 VCAN Regulation of CSPG4 1 0.38 0.15 0 45.00
104 INT271649 VCAN Regulation of Gene_expression of GFAP 1 0.23 0.15 0 45.00
105 INT271642 GFAP Regulation of CSPG4 1 0.18 0.15 0 45.00
106 INT271643 GFAP Regulation of Gene_expression of CSPG4 1 0.18 0.15 0 45.00
107 INT318379 Vmn1r7 Positive_regulation of PCS 1 0.00 0.72 0 44.24
108 INT327406 Lox Positive_regulation of Lox Positive_regulation of Ptk2 1 0.23 2.62 0.19 43.12
109 INT314052 Binding of VEGFA and Sp1 1 0.02 1.25 0.03 42.68
110 INT327405 Lox Positive_regulation of Ptk2 1 0.42 1.3 0.1 42.52
111 INT264731 Gene_expression of Hes1 Negative_regulation of Positive_regulation of Musd1 1 0.00 0.18 0 42.48
112 INT225258 Egf Positive_regulation of Gene_expression of S100a7a 1 0.07 1.7 0 39.76
113 INT179683 Binding of Col7a1 and Eln 2 0.00 3.02 0.19 38.56
114 INT224687 Il1 Positive_regulation of Bmp2 1 0.00 0.3 0.31 38.24
115 INT270915 AD5 Positive_regulation of Gene_expression of AAVS1 1 0.08 0.17 0.09 37.32
116 INT328775 Binding of Cd44 and Epcam 1 0.08 1.34 0 36.64
117 INT205158 Gene_expression of SPP1 Positive_regulation of Gene_expression of TNFSF11 1 0.11 1.08 0.08 35.48
118 INT78368 IGKV2D-29 Positive_regulation of PKIB 1 0.07 0.26 0.35 35.04
119 INT243622 Twist1 Regulation of Jak2 1 0.30 0.2 0.32 34.48
120 INT224681 Tlr2 Positive_regulation of Gene_expression of Il15 1 0.01 0.66 0.33 33.80
121 INT186388 Binding of IFNA1 and Ifnz 1 0.05 0.51 0 33.68
122 INT228496 Il4 Negative_regulation of Hand1 1 0.02 1.4 0.99 33.48
123 INT224691 Positive_regulation of Tlr4 Positive_regulation of Gene_expression of Il15 1 0.01 0.66 0.33 33.44
124 INT289707 F8 Positive_regulation of Tnxa 1 0.01 0 0 33.44
125 INT228498 Il10 Negative_regulation of Hand1 1 0.03 1.4 0.99 33.24
126 INT228495 Il13 Negative_regulation of Hand1 1 0.01 1.4 0.98 32.80
127 INT289708 Tnxa Positive_regulation of F2 1 0.00 0 0 31.36
128 INT289709 Gopc Positive_regulation of F2 1 0.05 0 0 31.36
129 INT258340 Binding of Ms4a1 and Cfb 1 0.04 0.32 0.16 30.48
130 INT243641 Twist1 Positive_regulation of Socs1 1 0.14 0.13 0.31 29.60
131 INT243634 Twist1 Regulation of Socs1 1 0.14 0.13 0.31 29.60
132 INT277995 TNF Positive_regulation of Gene_expression of Tnfrsf1a 1 0.03 1.48 0.22 26.60
133 INT277996 TNF Positive_regulation of Tnfrsf1a 1 0.03 1.48 0.22 26.60
134 INT200868 Binding of Cd9 and 4632428N05Rik 1 0.02 0.13 0 26.08
135 INT285382 Nat2 Positive_regulation of Localization of Chst10 1 0.03 0.08 0.06 26.00
136 INT285381 Scn11a Positive_regulation of Localization of Chst10 1 0.12 0.08 0.06 26.00
137 INT49242 Binding of Mc1r and Pomc 10 0.38 3.79 2.15 25.00
138 INT276303 Negative_regulation of AKT1 Negative_regulation of CCND1 1 0.01 0.58 0 24.72
139 INT243632 Il12a Positive_regulation of Nfatc1 1 0.03 0.44 0.16 24.20
140 INT224682 Mcl1 Regulation of Bak1 1 0.01 1.09 0.03 23.04
141 INT224689 Binding of Bak1 and Mcl1 1 0.01 1.09 0.03 23.04
142 INT224676 Binding of Bax and Mcl1 1 0.01 1.09 0.03 23.04
143 INT224690 Mcl1 Regulation of Bax 1 0.00 1.09 0.03 23.04
144 INT353440 Rnd3 Positive_regulation of Rnd3 Negative_regulation of Rock1 1 0.24 0 0 23.04
145 INT353438 Rnd3 Negative_regulation of Rock1 1 0.26 2.08 0 23.04
146 INT276374 Skp2 Regulation of Protein_catabolism of CIB1 1 0.00 0.58 0 20.72
147 INT199861 Xiap Regulation of Gopc 1 0.07 0.46 0 20.08
148 INT276382 Binding of CIB1 and Skp2 1 0.01 0.57 0 19.36
149 INT276302 Binding of SKP2 and CIB1 1 0.03 0.57 0 19.36
150 INT276393 Skp2 Regulation of CIB1 1 0.00 0.57 0 19.36
151 INT276379 Binding of SKP2 and Cdkn1b 1 0.02 0.57 0 18.96
152 INT276336 Skp2 Regulation of Cdkn1b 1 0.00 0.57 0 18.96
153 INT276335 Binding of Cdkn1b and Skp2 1 0.00 0.57 0 18.96
154 INT224696 TNF Positive_regulation of Gene_expression of Mcl1 1 0.01 1.07 0.05 18.40
155 INT308518 HSP90B1 Positive_regulation of Positive_regulation of SOAT1 1 0.00 0.65 0.18 16.60
156 INT287674 Skor2 Positive_regulation of Phosphorylation of Akt1 1 0.02 0 0.03 16.12
157 INT287675 Skor2 Positive_regulation of Phosphorylation of Gopc 1 0.02 0 0.03 16.12
158 INT243642 Binding of Nfatc1 and Twist1 1 0.08 0.23 0.12 12.52
159 INT172137 IL11 Negative_regulation of Gene_expression of TNF 1 0.09 0.73 0.47 11.68
160 INT258339 Binding of Aicda and Scara3 1 0.05 0.67 0.32 8.84
161 INT299745 Binding of Masp1 and IgG 1 0.03 0.69 0.26 8.56
162 INT328223 Mmp14 Regulation of Positive_regulation of Mmp13 1 0.07 0.69 0.29 5.96
163 INT328222 Mmp2 Regulation of Positive_regulation of Mmp13 1 0.05 0.69 0.28 5.12
164 INT149117 Binding of CD80 and CTLA4 31 0.52 12.7 7.73 5.00
165 INT155484 Binding of CD86 and CTLA4 15 0.52 8.85 6.09 5.00
166 INT176477 Binding of CXCR3 and CXCL10 14 0.25 10.61 5.87 5.00
167 INT126335 Binding of Pax3 and Tac1 6 0.07 6.22 5.27 5.00
168 INT64718 IL1B Positive_regulation of Gene_expression of IL6 15 0.59 9.37 4.48 5.00
169 INT121651 Binding of CXCL12 and CXCR4 13 0.48 17.61 3.52 5.00
170 INT194647 Binding of CD28 and CD80 15 0.40 4.9 3.22 5.00
171 INT194646 Binding of CD28 and CD86 7 0.40 2.69 2.21 5.00
172 INT239037 Binding of Cd28 and Cd86 9 0.16 3.69 2.14 5.00
173 INT201940 Binding of IL8 and CXCL10 2 0.28 2.46 1.86 5.00
174 INT89379 TNF Positive_regulation of Gene_expression of IL6 5 0.50 4.37 1.69 5.00
175 INT198653 TNF Positive_regulation of MIF 1 0.15 3.81 1.55 5.00
176 INT178986 Binding of MMP9 and TIMP1 4 0.47 2.58 1.33 5.00
177 INT186393 Binding of TNF and Tnfrsf1a 9 0.37 8.55 1.29 5.00
178 INT186355 Il23a Positive_regulation of Gene_expression of Il17a 4 0.12 3 1.24 5.00
179 INT172141 IL10 Negative_regulation of Gene_expression of HLA-DRA 2 0.14 0.89 1.23 5.00
180 INT260810 Binding of CXCL10 and CCL2 1 0.10 1.37 1.12 5.00
181 INT176474 Binding of CXCR3 and CXCL9 3 0.22 1.9 1.05 5.00
182 INT239038 Negative_regulation of Binding of Cd28 and Cd86 3 0.17 1.5 1.05 5.00
183 INT225158 Binding of CDK2 and CDKN1A 7 0.30 3.26 1.02 5.00
184 INT314037 THL Negative_regulation of Localization of Plau 1 0.17 1.64 0.99 5.00
185 INT195668 Binding of F2 and THBD 7 0.08 5.67 0.98 5.00
186 INT103796 IL1B Positive_regulation of Gene_expression of SELE 2 0.08 1 0.98 5.00
187 INT103651 IL1B Positive_regulation of Gene_expression of IL8 6 0.78 1.23 0.98 5.00
188 INT103133 TNF Positive_regulation of Gene_expression of IL8 2 0.48 1.26 0.96 5.00
189 INT133050 TNF Positive_regulation of Gene_expression of ICAM1 3 0.67 1.91 0.94 5.00
190 INT219154 Binding of HMGB1 and TLR4 2 0.17 4.45 0.93 5.00
191 INT221386 Tlr4 Positive_regulation of Gene_expression of IL8 6 0.14 3.53 0.9 5.00
192 INT203148 Mif Positive_regulation of Gene_expression of S100a8 1 0.00 1.56 0.87 5.00
193 INT202254 Binding of COMT and DRD2 1 0.41 0.23 0.86 5.00
194 INT196525 Binding of MMP2 and MMP9 2 0.32 2.49 0.78 5.00
195 INT164364 Binding of DRD2 and SUGT1 2 0.06 0.33 0.77 5.00
196 INT355704 Binding of Cia1 and Aia1 1 0.00 1.85 0.77 5.00
197 INT173112 IL1B Positive_regulation of Gene_expression of VCAM1 2 0.43 1.34 0.76 5.00
198 INT149192 TNF Positive_regulation of Gene_expression of VCAM1 3 0.57 1.4 0.76 5.00
199 INT292598 CNR1 Regulation of ABAT 1 0.08 0.32 0.75 5.00
200 INT292599 CNR1 Regulation of Localization of ABAT 1 0.08 0.32 0.75 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Severe Combined Immunodeficiency. They are ordered first by their pain relevance and then by number of times they were reported in Severe Combined Immunodeficiency. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 100.00
2 INT166935 Gene_expression of Prkdc 10 0.65 3.14 0.9 100.00
3 INT290726 Binding of Prkdc 1 0.03 1.05 0.13 100.00
4 INT170601 Positive_regulation of Gene_expression of GOPC 122 0.43 42.79 11.68 100.00
5 INT115464 Gene_expression of Plau 41 0.72 30.21 2.79 100.00
6 INT180394 Phosphorylation of Prkdc 2 0.07 0.6 0 100.00
7 INT180393 Positive_regulation of Gene_expression of Prkdc 3 0.49 1.17 0.26 100.00
8 INT175595 Gene_expression of DCLRE1C 1 0.25 0.87 0 100.00
9 INT68202 Gene_expression of ADA 26 0.68 23.15 5.18 100.00
10 INT61817 Gene_expression of Rhoc 1 0.18 1.49 0.08 100.00
11 INT327888 Localization of Prkdc 1 0.14 1.11 0.23 100.00
12 INT58208 Negative_regulation of Ctsl 8 0.53 3.49 1.91 100.00
13 INT78525 Gene_expression of RAD21 1 0.03 1.49 0.28 100.00
14 INT180196 Binding of DCLRE1C 1 0.08 0.49 0.14 100.00
15 INT34604 Binding of Ada 11 0.31 4.15 3.1 99.98
16 INT10889 Gene_expression of F8 60 0.78 41.36 5.06 99.96
17 INT115462 Positive_regulation of Gene_expression of Plau 14 0.65 7.35 0.53 99.96
18 INT171460 Protein_catabolism of Gtf3a 4 0.02 3.28 0.87 99.92
19 INT99942 Positive_regulation of Fasl 37 0.68 32.61 6.92 99.88
20 INT144534 Localization of Gem 3 0.37 1.62 0.41 99.88
21 INT207384 Gene_expression of Pgia1 3 0.14 18.55 6.87 99.84
22 INT316708 Positive_regulation of Gene_expression of Pgia1 1 0.12 11.52 4.19 99.84
23 INT66029 Negative_regulation of Tnf 100 0.59 84.28 48.16 99.84
24 INT74631 Gene_expression of UBXN11 19 0.75 6.11 0.57 99.80
25 INT120811 Gene_expression of Gopc 1174 0.59 428.49 150.55 99.76
26 INT293346 Binding of JAK3 1 0.12 0.34 0.26 99.76
27 INT170313 Gene_expression of Mmp1a 50 0.65 38.53 21.36 99.72
28 INT1284 Negative_regulation of Mmp13 20 0.57 36.21 14.91 99.68
29 INT153776 Positive_regulation of IL17A 42 0.64 34.58 14.82 99.68
30 INT145266 Gene_expression of IL17A 154 0.75 109.83 45.33 99.68
31 INT81629 Positive_regulation of Fas 58 0.70 59.63 12.94 99.64
32 INT138287 Gene_expression of Map2k1 69 0.65 46.14 1.02 99.60
33 INT261207 Binding of NEFL 2 0.06 1.09 0.04 99.60
34 INT53482 Gene_expression of ITIH4 75 0.77 58.87 26.05 99.60
35 INT275395 Regulation of Gene_expression of ITIH4 4 0.26 2.26 0.5 99.60
36 INT93626 Gene_expression of Fasl 118 0.75 115.24 25.11 99.52
37 INT194161 Gene_expression of Ly6g 6 0.65 4.83 0.6 99.52
38 INT93620 Positive_regulation of Gene_expression of Fasl 51 0.66 59.45 12.04 99.48
39 INT265449 Gene_expression of Aire 10 0.67 9.18 1.8 99.48
40 INT265442 Positive_regulation of Gene_expression of Aire 1 0.43 1.32 0.27 99.48
41 INT18322 Negative_regulation of Ins1 132 0.58 88.49 22.59 99.46
42 INT73048 Gene_expression of MMP9 268 0.77 159.75 57.81 99.44
43 INT26500 Gene_expression of MMP2 201 0.78 110.57 46.9 99.44
44 INT20375 Gene_expression of Hand1 213 0.60 148.51 54.53 99.44
45 INT226178 Gene_expression of thd 14 0.23 8.29 2.92 99.44
46 INT154527 Gene_expression of POU5F1 180 0.78 34.01 4.34 99.40
47 INT238376 Positive_regulation of TAM 3 0.04 6.75 0.51 99.38
48 INT16996 Gene_expression of PRTN3 113 0.75 85.61 22.57 99.36
49 INT6488 Gene_expression of Tnf 484 0.78 339.61 191.58 99.34
50 INT6489 Positive_regulation of Gene_expression of Tnf 140 0.70 92.31 67.85 99.34
51 INT191017 Localization of Cd79a 28 0.56 13.94 2.55 99.32
52 INT14448 Localization of COL5A2 34 0.67 17.35 2.85 99.32
53 INT173582 Negative_regulation of Localization of COL5A2 6 0.05 3.24 0.41 99.32
54 INT72747 Localization of IgG 55 0.53 30.88 4.19 99.32
55 INT116282 Gene_expression of Mmp13 83 0.75 45.4 20.18 99.28
56 INT212055 Protein_catabolism of Pif 1 0.02 3.09 0.19 99.28
57 INT194892 Regulation of Mmp1a 5 0.22 4.93 2.67 99.26
58 INT77307 Gene_expression of Bcl2 399 0.77 319.77 38 99.24
59 INT244733 Gene_expression of Folr1 1 0.43 4.57 0.33 99.24
60 INT191970 Positive_regulation of Ide 29 0.51 12.94 1.4 99.24
61 INT116281 Negative_regulation of Gene_expression of Mmp13 15 0.41 9.96 3.41 99.24
62 INT133768 Regulation of Fasl 10 0.44 10.24 3.32 99.16
63 INT6477 Gene_expression of IL1RN 213 0.77 114.69 58.62 99.14
64 INT6474 Positive_regulation of Gene_expression of IL1RN 34 0.69 21.87 10.99 99.14
65 INT244729 Gene_expression of Far 4 0.53 1.81 0.29 99.10
66 INT11238 Positive_regulation of ADA 33 0.70 39.7 9.98 99.06
67 INT32464 Regulation of Mmp13 12 0.44 6.46 3.61 99.06
68 INT110170 Positive_regulation of Positive_regulation of ADA 1 0.49 0.46 0.1 99.06
69 INT3214 Localization of Ins1 527 0.80 196.9 79.26 99.04
70 INT172452 Gene_expression of Myc 121 0.78 69.56 1.36 99.04
71 INT172445 Positive_regulation of Gene_expression of Myc 58 0.70 39.62 0.25 99.04
72 INT132903 Gene_expression of Cd34 65 0.72 33.95 2.2 99.04
73 INT3213 Gene_expression of Ins1 511 0.76 357.59 53.32 99.00
74 INT288122 Gene_expression of Taf1 1 0.10 0.77 0 99.00
75 INT288112 Negative_regulation of Gene_expression of Taf1 1 0.06 0.77 0 99.00
76 INT15174 Gene_expression of Itgam 238 0.73 104.92 29.26 98.94
77 INT9659 Gene_expression of Il6 991 0.78 715.11 265.57 98.92
78 INT328214 Regulation of Binding of Mmp1a 1 0.25 1.35 0.45 98.84
79 INT200193 Gene_expression of Col4a4 8 0.12 5.75 0.43 98.84
80 INT174838 Localization of INCENP 80 0.64 19.05 12.89 98.84
81 INT9144 Localization of MSC 18 0.56 10.17 3.69 98.84
82 INT68658 Gene_expression of NTSR1 17 0.77 7.88 2.32 98.82
83 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 98.80
84 INT186882 Gene_expression of RTEL1 13 0.27 13.45 0.49 98.80
85 INT867 Gene_expression of IFNA1 930 0.78 594.85 168.03 98.76
86 INT18522 Positive_regulation of Gene_expression of IFNA1 248 0.67 160.85 44.87 98.76
87 INT203491 Gene_expression of Msc 40 0.64 36.05 1.35 98.76
88 INT265573 Positive_regulation of Gene_expression of Msc 4 0.41 6.78 0.12 98.76
89 INT7532 Negative_regulation of Gene_expression of Ifng 33 0.59 18.56 13.14 98.74
90 INT218755 Positive_regulation of Regulation of Avp 1 0.03 0.74 0.04 98.72
91 INT21532 Negative_regulation of Gene_expression of Il2 47 0.59 20.43 16.96 98.72
92 INT17564 Gene_expression of Gpt 322 0.75 208.51 60.36 98.72
93 INT39516 Gene_expression of Alb 81 0.75 30.08 6.59 98.72
94 INT73670 Gene_expression of Vcam1 128 0.78 123.79 24.96 98.68
95 INT30206 Negative_regulation of ADA 17 0.59 10.03 5.63 98.68
96 INT73047 Positive_regulation of MMP9 133 0.68 73.22 26.42 98.64
97 INT103245 Positive_regulation of Gene_expression of MMP9 64 0.68 36.86 15.7 98.64
98 INT7534 Gene_expression of Ifng 193 0.78 111.02 68.6 98.52
99 INT15768 Gene_expression of Il1a 20 0.71 9.31 8.78 98.52
100 INT47301 Gene_expression of Ctsl 27 0.76 7.72 9.32 98.52
101 INT47305 Positive_regulation of Gene_expression of Ctsl 5 0.59 2.06 1.12 98.52
102 INT223902 Positive_regulation of Ifi35 14 0.67 17.08 0.4 98.52
103 INT258328 Gene_expression of Aicda 76 0.71 58.29 16.86 98.50
104 INT167052 Gene_expression of Cr2 43 0.56 25.7 7.76 98.50
105 INT218757 Regulation of Pnp 4 0.15 5.51 0.04 98.48
106 INT88318 Gene_expression of CXCR4 208 0.77 189.67 31.72 98.48
107 INT258326 Gene_expression of Scara3 1 0.11 5.17 1.87 98.48
108 INT258308 Positive_regulation of Gene_expression of Scara3 1 0.07 0.94 0.3 98.48
109 INT61257 Gene_expression of Sele 79 0.77 70.97 17.78 98.46
110 INT74218 Binding of TAM 4 0.36 4.31 0.76 98.44
111 INT126906 Positive_regulation of Gene_expression of H2 12 0.21 9.2 1.91 98.40
112 INT939 Gene_expression of PAEP 86 0.77 31.02 8.59 98.24
113 INT9658 Negative_regulation of Gene_expression of Il6 110 0.59 66.29 32.58 98.20
114 INT151168 Gene_expression of Pten 60 0.78 35.63 10.54 98.20
115 INT101590 Gene_expression of SERPINB5 8 0.75 9.35 1.19 98.20
116 INT19806 Regulation of Avp 29 0.53 14.17 6.94 98.16
117 INT280594 Gene_expression of SPHK1 2 0.78 71.47 0.19 98.16
118 INT55737 Positive_regulation of MMP2 101 0.68 59.11 27.71 98.16
119 INT26501 Positive_regulation of Gene_expression of MMP2 51 0.67 39 15.16 98.16
120 INT335530 Positive_regulation of Gene_expression of SPHK1 1 0.69 21.31 0 98.16
121 INT1758 Positive_regulation of Gene_expression of TIMP1 62 0.69 31.72 13.98 98.16
122 INT87239 Localization of Il12a 51 0.75 31.95 12.05 98.12
123 INT108761 Localization of Alms1 24 0.70 13.92 3.74 98.08
124 INT93361 Gene_expression of Trp53 208 0.78 175.35 16.65 98.00
125 INT156734 Gene_expression of BBC3 3 0.58 2.41 0.46 98.00
126 INT206806 Phosphorylation of CD24 2 0.63 1.35 0 97.98
127 INT327892 Phosphorylation of PROM1 1 0.21 0.99 0 97.98
128 INT9852 Positive_regulation of Gpt 563 0.70 364.64 146.82 97.96
129 INT175522 Positive_regulation of Map3k15 1 0.02 0.73 0 97.92
130 INT10796 Gene_expression of CYP2B6 131 0.77 30.14 35.27 97.88
131 INT39972 Gene_expression of CPA1 7 0.65 3.17 0.26 97.88
132 INT28216 Gene_expression of HRAS 173 0.75 93.97 20.78 97.88
133 INT18772 Positive_regulation of Gene_expression of CYP2B6 14 0.49 2.93 5.4 97.88
134 INT80175 Positive_regulation of Gene_expression of HRAS 24 0.67 14.69 3.97 97.88
135 INT12131 Gene_expression of POR 17 0.77 9.42 2.17 97.88
136 INT12132 Positive_regulation of Gene_expression of POR 5 0.31 1.96 0.27 97.88
137 INT174245 Positive_regulation of Gene_expression of CPA1 1 0.11 0.85 0 97.88
138 INT96937 Gene_expression of Mmp9 191 0.75 150.3 56.01 97.84
139 INT223900 Gene_expression of Ifi35 6 0.65 10.52 0 97.84
140 INT258318 Localization of Scara3 1 0.11 0.61 0.18 97.84
141 INT1759 Gene_expression of TIMP1 267 0.77 133.87 59.29 97.84
142 INT158016 Positive_regulation of VEGFC 7 0.49 6.58 2.18 97.84
143 INT288114 Negative_regulation of Gene_expression of Ifi35 1 0.02 0.76 0 97.84
144 INT279628 Negative_regulation of Ar 5 0.04 6.1 0.25 97.76
145 INT206030 Localization of Hivan1 3 0.09 4.9 0.15 97.76
146 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 97.68
147 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210 97.68
148 INT96155 Gene_expression of Cd86 134 0.77 50.56 17.13 97.60
149 INT204852 Gene_expression of Cd83 7 0.48 3.15 0.76 97.60
150 INT39758 Gene_expression of Fn1 57 0.65 34.38 6.02 97.56
151 INT129589 Positive_regulation of St13 6 0.38 3 2.61 97.52
152 INT170324 Negative_regulation of Gene_expression of Mmp1a 8 0.13 6.28 2.94 97.52
153 INT196594 Localization of CFD 4 0.65 4.36 0.39 97.44
154 INT86295 Gene_expression of Mmp2 114 0.76 73.68 24.25 97.36
155 INT172797 Negative_regulation of Mmp1a 8 0.24 6.47 2.74 97.36
156 INT328215 Binding of Mmp1a 1 0.20 1.35 0.45 97.36
157 INT114993 Binding of Myo5a 15 0.30 11.46 5.48 97.24
158 INT11303 Gene_expression of Avp 116 0.78 39.23 23.88 97.20
159 INT170294 Regulation of Gene_expression of Mmp13 5 0.44 4.25 1.26 97.20
160 INT60694 Gene_expression of Il10 567 0.78 369.48 143.69 97.16
161 INT53575 Regulation of Gene_expression of Tnf 46 0.62 34.35 20.63 97.16
162 INT68683 Regulation of Gene_expression of VEGFA 143 0.62 104.19 20.14 97.16
163 INT73674 Regulation of Gene_expression of Vcam1 9 0.33 11.23 1.64 97.16
164 INT62543 Gene_expression of Icam1 231 0.78 187.58 52.71 97.16
165 INT48078 Regulation of Gene_expression of Il1b 15 0.62 14.78 9.53 97.16
166 INT62545 Regulation of Gene_expression of Icam1 17 0.49 14.26 4.06 97.16
167 INT73671 Regulation of Gene_expression of Sele 8 0.45 7.01 2.39 97.16
168 INT73668 Regulation of Gene_expression of Pcdhb16 1 0.05 2.43 0.18 97.16
169 INT73669 Regulation of Gene_expression of Il1f6 1 0.02 2.43 0.18 97.16
170 INT73672 Gene_expression of Pcdhb16 4 0.10 6.52 1.12 97.16
171 INT15769 Gene_expression of Il1b 146 0.78 114.51 75.35 97.16
172 INT73675 Gene_expression of Il1f6 2 0.09 3.3 0.37 97.16
173 INT83797 Gene_expression of Bcl2l1 124 0.77 94.55 22.39 97.08
174 INT120089 Negative_regulation of Ccr5 7 0.58 10.36 5.91 97.04
175 INT8793 Gene_expression of H2 58 0.75 26.36 7.07 96.88
176 INT117660 Gene_expression of Prom1 50 0.73 39.62 3.07 96.88
177 INT175423 Positive_regulation of TSC1 25 0.36 21.81 0.45 96.88
178 INT172963 Negative_regulation of Pdgfa 11 0.21 12.94 2.64 96.80
179 INT109511 Gene_expression of Bax 133 0.78 113.22 14.36 96.72
180 INT60691 Gene_expression of Il12a 331 0.78 208.03 75.96 96.56
181 INT207383 Positive_regulation of Pgia1 4 0.09 6.39 2.14 96.56
182 INT60690 Positive_regulation of Gene_expression of Il12a 69 0.63 41.41 20.85 96.56
183 INT297520 Gene_expression of T(2;4)1Ca 1 0.07 1.26 0.17 96.56
184 INT91209 Binding of VIM 15 0.36 12.02 0.53 96.52
185 INT61619 Gene_expression of IL12A 194 0.77 146.07 41.97 96.48
186 INT95028 Gene_expression of Chrm4 8 0.39 2.66 0.99 96.44
187 INT190665 Gene_expression of Mixl1 4 0.35 2.54 0.2 96.44
188 INT170054 Negative_regulation of Gopc 280 0.38 117.89 42.4 96.40
189 INT105021 Binding of GOPC 187 0.40 60.39 20.38 96.32
190 INT60695 Positive_regulation of Gene_expression of Il10 154 0.70 120.28 43.07 96.28
191 INT1125 Positive_regulation of IGHG3 130 0.69 112.07 13.18 96.28
192 INT142984 Positive_regulation of S1pr1 13 0.70 7.9 3.84 96.20
193 INT71602 Negative_regulation of Trp53 84 0.59 67.77 3.68 96.20
194 INT48141 Binding of Csf3 18 0.39 9.93 1.71 96.16
195 INT332453 Positive_regulation of Phosphorylation of Csf3 1 0.27 0.43 0.04 96.16
196 INT227332 Phosphorylation of Csf3 2 0.43 2.01 0.31 96.16
197 INT258323 Positive_regulation of Scara3 1 0.08 1.37 0.47 96.12
198 INT9657 Positive_regulation of Gene_expression of Il6 237 0.70 180.45 63.6 96.00
199 INT214710 Negative_regulation of Bok 2 0.10 2.22 0.14 95.92
200 INT5206 Gene_expression of AR 316 0.78 113.83 27.29 95.80
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