D:Sexually Transmitted Diseases

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Disease Term
Synonyms Disease Sexually Transmitted, Disease Venereal, Diseases Sexually Transmitted, Diseases Venereal, Sexually Transmitted Disease, Std Sexually Transmitted Disease, Stds, Venereal Disease, VENEREAL DISEASES
Documents 545
Hot Single Events 39
Hot Interactions 1

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Sexually Transmitted Diseases. They are ordered first by their relevance to Sexually Transmitted Diseases and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT244401 Binding of HPV6AI1 and HEPACAM 1 0.00 4.33 0 99.48
2 INT321642 Binding of Cd3e and Spn 1 0.00 1.08 0 23.72
3 INT179502 Binding of Cd14 and Tlr4 29 0.39 13.77 5.73 5.00
4 INT175329 Binding of ICAM1 and ITGAL 14 0.18 10.06 2.81 5.00
5 INT168295 PROC Regulation of Gene_expression of VEGFA 2 0.00 1.6 0.67 5.00
6 INT137141 Binding of HIVEP1 and ITIH4 2 0.16 1.44 0.56 5.00
7 INT234755 IL10 Positive_regulation of IFN1@ 1 0.08 0.68 0.23 5.00
8 INT189795 Tlr4 Positive_regulation of Cd14 1 0.12 0.77 0.19 5.00
9 INT259023 CADPS Positive_regulation of Binding of SH2B2 1 0.06 2.05 0.14 5.00
10 INT189796 Binding of EHHADH and Cd14 1 0.13 0.9 0.14 5.00
11 INT297589 Binding of HAT1 and Il10 1 0.00 1.14 0.08 5.00
12 INT297559 Binding of IL6 and HAT1 1 0.00 1.13 0.08 5.00
13 INT186860 MIR181A2HG Regulation of Cd86 1 0.02 1.05 0.07 5.00
14 INT186814 MIR181A2HG Regulation of ICAM1 1 0.01 1.05 0.07 5.00
15 INT297562 TNF Positive_regulation of IFNA1 1 0.00 0.62 0.06 5.00
16 INT266082 PROC Regulation of Localization of VEGFA 1 0.00 0.84 0.05 5.00
17 INT290727 Binding of Prdm6 and Arsi 1 0.01 0.17 0.04 5.00
18 INT266078 VEGFA Positive_regulation of DBI 1 0.10 0.45 0.04 5.00
19 INT266074 LGALS1 Regulation of Gene_expression of PAEP 1 0.14 0.43 0.03 5.00
20 INT266075 LIF Regulation of Gene_expression of PAEP 1 0.19 0.43 0.03 5.00
21 INT266070 LIF Regulation of Gene_expression of PAPPA 1 0.35 0.49 0.03 5.00
22 INT266072 LGALS1 Regulation of Gene_expression of LIF 1 0.17 0.43 0.03 5.00
23 INT266067 PAPPA Regulation of Gene_expression of LIF 1 0.35 0.49 0.03 5.00
24 INT266076 LIF Regulation of Gene_expression of LGALS1 1 0.17 0.43 0.03 5.00
25 INT266081 PAPPA Regulation of Gene_expression of LGALS1 1 0.24 0.49 0.03 5.00
26 INT266077 LGALS1 Regulation of Gene_expression of PAPPA 1 0.24 0.49 0.03 5.00
27 INT266073 PAPPA Regulation of Gene_expression of PAEP 1 0.27 0.49 0.03 5.00
28 INT297560 Binding of HSD11B1 and APOL1 1 0.04 0.88 0 5.00
29 INT319483 Binding of LCT and HSR 1 0.11 0.23 0 5.00
30 INT266080 Binding of PAPPA and MUC16 1 0.40 0.74 0 5.00
31 INT266068 Binding of CHKB and MUC16 1 0.22 0.74 0 5.00
32 INT297563 Binding of HSD11B1 and TBPL1 1 0.01 0.41 0 5.00
33 INT275190 Localization of CD4 Positive_regulation of Positive_regulation of LCK 1 0.10 0.99 0 5.00
34 INT297558 Binding of APOL1 and SRA1 1 0.22 0.56 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Sexually Transmitted Diseases. They are ordered first by their pain relevance and then by number of times they were reported in Sexually Transmitted Diseases. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT11587 Gene_expression of CSF2 645 0.78 544.38 93.89 100.00
2 INT162058 Binding of GGH 8 0.37 3.45 0.2 100.00
3 INT11831 Positive_regulation of pid 13 0.40 23.37 1.54 99.70
4 INT60252 Binding of HIVEP1 59 0.32 65.12 5.06 99.60
5 INT36133 Binding of pid 22 0.42 31.34 4.1 99.48
6 INT3758 Gene_expression of ALB 326 0.78 184.65 38.75 99.20
7 INT8683 Positive_regulation of F3 31 0.67 42.89 6.21 98.94
8 INT29879 Positive_regulation of GGH 9 0.70 3.13 2.62 98.48
9 INT148941 Regulation of Epc1 6 0.16 4.05 1.05 98.40
10 INT56376 Negative_regulation of AMBP 29 0.35 21.49 2.59 98.04
11 INT56374 Gene_expression of AMBP 34 0.54 35.85 6.25 95.76
12 INT225056 Positive_regulation of Gene_expression of AMBP 4 0.37 5.45 0.75 95.76
13 INT4216 Gene_expression of CD40LG 328 0.78 256.02 44.23 95.52
14 INT39243 Regulation of TMPO 20 0.61 5.66 2.67 95.44
15 INT310439 Regulation of POLA1 1 0.24 2.21 0 95.44
16 INT22128 Positive_regulation of HIVEP1 61 0.43 70.52 6.07 95.12
17 INT78024 Gene_expression of ACLY 73 0.75 59.15 18.54 95.04
18 INT35584 Binding of ACLY 22 0.35 31.78 7.17 94.92
19 INT13240 Gene_expression of TF 94 0.76 57.81 10.99 94.36
20 INT122924 Binding of ipv 27 0.42 31.81 1.99 92.76
21 INT56277 Binding of MYH9 3 0.36 2.37 1.11 91.56
22 INT17275 Gene_expression of HIVEP1 267 0.75 232.07 24.06 90.32
23 INT244404 Binding of HEPACAM 21 0.02 35.88 0.09 88.28
24 INT82918 Binding of AMBP 23 0.39 23.31 1.71 86.48
25 INT216858 Negative_regulation of PID1 4 0.35 6.3 1.11 86.16
26 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 86.12
27 INT10832 Gene_expression of IL8 1050 0.78 698.72 270 86.12
28 INT249662 Regulation of Gene_expression of AGRP 1 0.22 0.45 0 86.12
29 INT9408 Positive_regulation of Crp 296 0.69 242.27 57.35 86.08
30 INT141665 Gene_expression of AGRP 83 0.67 43.43 4.24 85.88
31 INT290728 Gene_expression of Depmq1 1 0.01 0.79 0.92 84.92
32 INT238096 Positive_regulation of ELL 4 0.09 2.68 0.16 83.56
33 INT2120 Gene_expression of CD79A 159 0.78 111.69 17.16 82.56
34 INT4004 Gene_expression of IGHG3 321 0.71 221.03 42.33 82.56
35 INT3952 Negative_regulation of ALB 116 0.59 72.18 18.35 82.00
36 INT18773 Localization of ALB 117 0.80 69.18 13.8 82.00
37 INT195817 Gene_expression of ipv 28 0.58 31.04 1.86 81.64
38 INT70087 Negative_regulation of TGM1 2 0.50 2.62 0.21 80.96
39 INT77281 Negative_regulation of HIVEP1 132 0.49 102.78 5.36 80.04
40 INT6481 Binding of TNF 624 0.48 510.2 214.82 79.68
41 INT310441 Regulation of EXTL3 1 0.26 0.97 0 78.72
42 INT3361 Positive_regulation of Esr1 273 0.69 208.53 44.81 77.60
43 INT324675 Localization of SNORA1 1 0.73 1.95 0.06 77.44
44 INT7383 Localization of VIP 53 0.81 17.7 22.65 77.28
45 INT114993 Binding of Myo5a 15 0.30 11.46 5.48 76.92
46 INT33567 Gene_expression of CALM1 139 0.67 48.85 56.14 76.08
47 INT8512 Gene_expression of PREP 17 0.65 7.98 2.5 74.80
48 INT39244 Gene_expression of TMPO 137 0.77 14.55 11.83 74.32
49 INT23174 Gene_expression of NLRP3 51 0.72 35.49 6.47 72.48
50 INT324529 Negative_regulation of Binding of PREP 1 0.37 2.48 1.05 70.04
51 INT1926 Positive_regulation of PLAT 54 0.66 31.42 6.49 69.52
52 INT185502 Binding of PREP 6 0.37 4.04 1.09 69.00
53 INT160280 Positive_regulation of ipv 14 0.44 15.73 1.02 68.84
54 INT45878 Gene_expression of NEU1 14 0.65 7.28 0.47 68.80
55 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98 67.68
56 INT81155 Localization of CDCP1 5 0.08 4.49 1.4 67.12
57 INT33661 Regulation of Tbpl1 7 0.44 5.36 3.26 66.64
58 INT324530 Positive_regulation of Gene_expression of PREP 2 0.44 1.45 0.58 65.56
59 INT165054 Gene_expression of MIR146A 45 0.58 82.87 28.82 64.80
60 INT56375 Positive_regulation of AMBP 25 0.60 21.24 2.22 63.20
61 INT177778 Gene_expression of SQLE 28 0.40 16.42 2.08 62.88
62 INT170813 Gene_expression of Prdm6 11 0.65 4.35 0.88 60.88
63 INT23676 Gene_expression of Chrna7 47 0.75 23.66 9.51 58.20
64 INT9852 Positive_regulation of Gpt 563 0.70 364.64 146.82 57.92
65 INT76924 Positive_regulation of Slc17a5 71 0.70 41.21 19.31 57.92
66 INT756 Gene_expression of C3 138 0.75 100.6 19.2 56.20
67 INT9951 Gene_expression of ANGPTL5 45 0.53 37.2 6.44 55.68
68 INT191017 Localization of Cd79a 28 0.56 13.94 2.55 55.48
69 INT45167 Positive_regulation of ASAP1 32 0.60 17.09 1.84 53.44
70 INT120335 Gene_expression of SNAP25 24 0.65 9.44 5.83 51.80
71 INT85885 Positive_regulation of SNAP25 8 0.69 2.74 2.84 51.80
72 INT5433 Regulation of polymerase 8 0.03 4.2 0.15 49.96
73 INT79358 Gene_expression of ERVW-1 65 0.75 29.9 1.31 48.68
74 INT4649 Positive_regulation of Chrna7 17 0.50 5.48 3.92 46.48
75 INT7206 Binding of HBG1 14 0.47 3.44 2.14 44.68
76 INT75869 Gene_expression of Acsl1 24 0.45 27.76 3.66 44.44
77 INT73498 Gene_expression of IL13 117 0.44 83.85 32.26 44.08
78 INT36287 Binding of CD4 96 0.47 58.93 11.88 44.08
79 INT108559 Gene_expression of Pol 46 0.45 30.07 1.14 43.92
80 INT69157 Gene_expression of IL5 127 0.77 102.58 26.81 43.20
81 INT56298 Gene_expression of IL4 306 0.78 182.18 72.92 42.72
82 INT191018 Positive_regulation of Gene_expression of Cd79a 12 0.26 8.01 1.05 41.92
83 INT39416 Gene_expression of Cd79a 81 0.64 45.17 6.08 41.00
84 INT23330 Binding of Chrna7 79 0.48 10.06 35.5 39.48
85 INT16452 Negative_regulation of SERPIND1 13 0.59 8.43 1.83 39.00
86 INT30533 Negative_regulation of Epc1 13 0.38 5.69 1.72 38.56
87 INT36132 Negative_regulation of pid 12 0.43 15.15 1.73 38.16
88 INT55890 Regulation of RPS6KB2 2 0.39 0.44 0.16 35.20
89 INT86998 Regulation of HIVEP1 49 0.44 37.83 4 35.12
90 INT160251 Gene_expression of Myo5a 48 0.63 37.14 3.16 35.04
91 INT169387 Regulation of Gene_expression of Chrna7 4 0.36 2.19 1.63 34.80
92 INT167847 Positive_regulation of Gene_expression of Chrna7 7 0.49 3.02 1.57 34.56
93 INT89551 Gene_expression of NEFM 13 0.44 4.74 2.22 34.52
94 INT203646 Gene_expression of STIP1 26 0.63 23.57 1.14 34.16
95 INT188756 Positive_regulation of AGRP 43 0.60 23.67 2.51 33.24
96 INT170332 Gene_expression of IFN1@ 477 0.75 275.21 69.65 31.52
97 INT57178 Regulation of REG1A 4 0.38 1.77 1.34 31.44
98 INT5056 Gene_expression of IFNG 216 0.78 137.52 74.57 31.12
99 INT6782 Gene_expression of SCN5A 156 0.78 33.13 17.88 25.72
100 INT56809 Binding of Tlr4 184 0.48 106.02 31.18 25.56
101 INT197194 Binding of DURS1 3 0.27 4.2 0.33 25.16
102 INT10248 Gene_expression of KRT20 436 0.78 231.96 32.88 25.08
103 INT36301 Negative_regulation of TOP2A 3 0.57 2.66 0 25.00
104 INT36286 Binding of Cd3e 33 0.36 10.11 3.21 23.72
105 INT16245 Binding of Spn 4 0.31 3.83 0.45 23.72
106 INT36245 Negative_regulation of Gene_expression of ELANE 11 0.40 5.32 1.88 20.92
107 INT8580 Gene_expression of ELANE 132 0.75 62.98 21.79 20.52
108 INT2609 Localization of ELANE 111 0.81 50.22 26.63 20.48
109 INT77670 Positive_regulation of ACLY 24 0.49 21.68 3.12 18.96
110 INT7533 Gene_expression of Tlr4 720 0.78 343.22 121.57 18.16
111 INT43906 Regulation of Tlr4 71 0.53 35.18 15.49 17.40
112 INT186838 Gene_expression of C2orf65 1 0.07 3.07 0 15.88
113 INT186851 Gene_expression of C6orf47 1 0.07 1.56 0 15.44
114 INT186857 Gene_expression of LINC00484 1 0.10 1.54 0 15.44
115 INT11340 Positive_regulation of SLC17A5 120 0.67 113.52 14.5 15.28
116 INT230372 Negative_regulation of ELL 5 0.03 1.35 0 11.48
117 INT47425 Localization of Chrna7 11 0.81 6.7 1.86 11.04
118 INT5058 Positive_regulation of IFNA1 356 0.70 245.75 60.52 7.40
119 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 5.00
120 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 5.00
121 INT6852 Localization of TNF 883 0.81 705.95 270.84 5.00
122 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97 5.00
123 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 5.00
124 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210 5.00
125 INT15516 Gene_expression of Crp 711 0.77 615.33 173.09 5.00
126 INT867 Gene_expression of IFNA1 930 0.78 594.85 168.03 5.00
127 INT1114 Localization of Ins1 748 0.80 192.95 165.48 5.00
128 INT15515 Positive_regulation of Crp 700 0.70 604.24 150.15 5.00
129 INT5116 Gene_expression of IL2 670 0.78 291.13 146.69 5.00
130 INT60694 Gene_expression of Il10 567 0.78 369.48 143.69 5.00
131 INT9235 Negative_regulation of Gene_expression of TNF 346 0.59 252.98 118.61 5.00
132 INT20374 Gene_expression of Il4 515 0.76 306.15 114.12 5.00
133 INT11051 Positive_regulation of Gene_expression of IL6 415 0.69 319.21 109.3 5.00
134 INT60526 Gene_expression of IL10 449 0.78 292.71 107.84 5.00
135 INT12082 Localization of IL6 365 0.81 241.78 105.78 5.00
136 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74 5.00
137 INT6437 Binding of YY1 154 0.47 26.3 90.46 5.00
138 INT48408 Gene_expression of ICAM1 494 0.78 340.08 88.6 5.00
139 INT914 Positive_regulation of GH1 292 0.69 100.7 84.91 5.00
140 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65 5.00
141 INT3657 Gene_expression of Ins1 514 0.78 321.69 75.76 5.00
142 INT10837 Positive_regulation of Gene_expression of IL8 294 0.70 190.08 70.34 5.00
143 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73 5.00
144 INT6849 Localization of IL1B 229 0.81 112.56 69.63 5.00
145 INT4960 Positive_regulation of CSF2 285 0.70 256.73 65.73 5.00
146 INT1951 Positive_regulation of Tlr4 345 0.70 176.99 62.42 5.00
147 INT9196 Gene_expression of PTGS1 215 0.77 96.99 60.5 5.00
148 INT17564 Gene_expression of Gpt 322 0.75 208.51 60.36 5.00
149 INT546 Binding of ALB 311 0.48 85.98 60.14 5.00
150 INT4509 Gene_expression of IgG 426 0.76 293.69 56.64 5.00
151 INT1200 Negative_regulation of Ins1 274 0.58 155.17 56.14 5.00
152 INT1579 Gene_expression of PRL 279 0.78 119.2 55.41 5.00
153 INT78899 Gene_expression of CCL5 155 0.77 84.02 55.09 5.00
154 INT82650 Gene_expression of Bcl2 312 0.78 211.71 55.03 5.00
155 INT117223 Gene_expression of TLR4 348 0.78 206.18 54.42 5.00
156 INT52264 Gene_expression of IK 180 0.77 90.87 51.87 5.00
157 INT6473 Positive_regulation of Gene_expression of IL1B 204 0.70 117.23 50.86 5.00
158 INT1199 Positive_regulation of INS 579 0.70 399.64 50.43 5.00
159 INT18522 Positive_regulation of Gene_expression of IFNA1 248 0.67 160.85 44.87 5.00
160 INT73502 Positive_regulation of IL10 154 0.69 124.87 43.5 5.00
161 INT100939 Gene_expression of Il13 176 0.73 125.1 43.38 5.00
162 INT13354 Transcription of TNF 108 0.72 85.81 42.32 5.00
163 INT13556 Gene_expression of CD4 367 0.78 230.82 41.74 5.00
164 INT88322 Gene_expression of CCR5 111 0.78 77.36 39.84 5.00
165 INT62827 Positive_regulation of ICAM1 184 0.70 180.95 36.28 5.00
166 INT133028 Gene_expression of TLR2 209 0.73 131.92 36.17 5.00
167 INT101992 Localization of VEGFA 413 0.81 258.23 36.15 5.00
168 INT72651 Gene_expression of TH1L 114 0.75 80.15 35.15 5.00
169 INT49214 Gene_expression of Cd4 269 0.78 154.22 34.05 5.00
170 INT10763 Localization of IL2 157 0.80 81.11 33.21 5.00
171 INT6302 Binding of IFNA1 196 0.48 133.85 32.73 5.00
172 INT48693 Regulation of VEGFA 268 0.62 191.88 31.52 5.00
173 INT13186 Positive_regulation of Il4 113 0.68 71.22 31.4 5.00
174 INT34729 Positive_regulation of IFN1@ 233 0.67 128.04 30.38 5.00
175 INT90792 Localization of Il10 144 0.80 87.88 30.03 5.00
176 INT32165 Binding of CALM1 92 0.48 24.19 29.57 5.00
177 INT8097 Gene_expression of EGF 122 0.77 75.94 28.47 5.00
178 INT22211 Positive_regulation of CYP3A4 110 0.70 22 28.27 5.00
179 INT5653 Positive_regulation of ELANE 136 0.70 72.78 27.94 5.00
180 INT6717 Negative_regulation of YY1 45 0.57 15.35 27.8 5.00
181 INT12129 Gene_expression of CYP3A4 107 0.78 23.11 27.6 5.00
182 INT3760 Positive_regulation of ALB 142 0.70 87.46 26.7 5.00
183 INT19856 Gene_expression of CD8A 240 0.75 147.86 26.39 5.00
184 INT53482 Gene_expression of ITIH4 75 0.77 58.87 26.05 5.00
185 INT70048 Positive_regulation of Gene_expression of IL10 90 0.55 71.34 25.66 5.00
186 INT68758 Positive_regulation of Ros1 125 0.46 82.72 25.27 5.00
187 INT2614 Gene_expression of CGA 187 0.78 105.89 24.77 5.00
188 INT55583 Localization of IFNA1 135 0.78 85.07 24.13 5.00
189 INT5055 Positive_regulation of IFNG 89 0.69 64.03 23.05 5.00
190 INT74423 Localization of IL10 91 0.80 61.6 22.95 5.00
191 INT8640 Positive_regulation of HSD11B1 332 0.67 377.84 22.36 5.00
192 INT5905 Negative_regulation of ELANE 113 0.59 47.43 22.09 5.00
193 INT3589 Positive_regulation of SCN5A 101 0.57 46.01 21.73 5.00
194 INT78057 Localization of Tlr4 140 0.77 67.75 21.72 5.00
195 INT34488 Negative_regulation of MMP2 85 0.59 41.98 21.72 5.00
196 INT7535 Negative_regulation of Tlr4 111 0.56 56.84 21.37 5.00
197 INT5328 Positive_regulation of CD4 191 0.69 133.43 21.31 5.00
198 INT43226 Gene_expression of Hivep3 75 0.71 30.53 21.14 5.00
199 INT11161 Gene_expression of HLA-DRB1 121 0.78 75.33 20.96 5.00
200 INT78901 Localization of CCL5 67 0.78 40.79 20.59 5.00
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