D:Short Bowel Syndrome

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Disease Term
Synonyms Bowel Syndrome Short, Bowel Syndromes Short, SHORT BOWEL SYNDROMES, Syndrome Short Bowel, Syndromes Short Bowel
Documents 75
Hot Single Events 13
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Short Bowel Syndrome. They are ordered first by their relevance to Short Bowel Syndrome and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT181168 Binding of CD79A and TAPBP 1 0.10 0.7 0.04 50.00
2 INT181169 TAPBP Negative_regulation of MALT1 1 0.00 0.48 0 50.00
3 INT181167 TAPBP Negative_regulation of CD79A 1 0.11 0.48 0 50.00
4 INT181165 TAPBP Regulation of Gene_expression of CD79A 1 0.07 0.35 0 50.00
5 INT336337 Glp2r Positive_regulation of Gene_expression of Col2a1 1 0.01 0.7 0.14 43.36
6 INT336340 Glp2r Positive_regulation of Gene_expression of TGFB1 1 0.14 0.67 0.39 5.00
7 INT336339 Glp2r Positive_regulation of Timp1 1 0.16 1.82 0.36 5.00
8 INT336336 Il10 Regulation of Il13 1 0.04 0.67 0.34 5.00
9 INT185092 CRP Positive_regulation of ESR1 1 0.06 2.83 0.28 5.00
10 INT336335 Glp2r Regulation of Mmp13 1 0.06 0.68 0.28 5.00
11 INT277705 SMAP2 Regulation of TNF 1 0.01 1.23 0.25 5.00
12 INT336338 Glp2r Positive_regulation of Gene_expression of Igf1 1 0.14 0.24 0.05 5.00
13 INT241536 Binding of Abcb1b and Abcg2 1 0.10 0.17 0.04 5.00
14 INT287088 Binding of EEC1 and Vamp3 1 0.09 1.02 0 5.00
15 INT241535 Abl1 Regulation of Positive_regulation of Jak2 1 0.10 0.53 0 5.00
16 INT241537 Negative_regulation of Binding of Abl1 and Src 1 0.04 0.14 0 5.00
17 INT241539 Binding of Abl1 and Lyn 1 0.09 0.14 0 5.00
18 INT241534 Binding of Abl1 and Src 1 0.04 0.14 0 5.00
19 INT241538 Negative_regulation of Binding of Abl1 and Lyn 1 0.11 0.14 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Short Bowel Syndrome. They are ordered first by their pain relevance and then by number of times they were reported in Short Bowel Syndrome. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT181177 Gene_expression of CYLD 5 0.69 24.96 0.89 100.00
2 INT181179 Binding of CYLD 4 0.43 7.06 0.39 100.00
3 INT19900 Binding of GHRH 22 0.37 5.75 5 99.84
4 INT132528 Gene_expression of TAPBP 17 0.65 5.93 0.69 97.80
5 INT9884 Localization of CD79A 41 0.78 21.75 3.06 97.64
6 INT1126 Negative_regulation of CD79A 46 0.59 31.07 6 97.58
7 INT2120 Gene_expression of CD79A 159 0.78 111.69 17.16 97.32
8 INT92137 Binding of GALT 4 0.36 2.99 0.92 96.04
9 INT546 Binding of ALB 311 0.48 85.98 60.14 89.40
10 INT139674 Regulation of TAPBP 2 0.44 1.34 0.46 88.76
11 INT287082 Gene_expression of Vamp3 1 0.18 0.99 0.11 86.40
12 INT1118 Gene_expression of C6orf25 73 0.77 47.24 9.1 83.72
13 INT4004 Gene_expression of IGHG3 321 0.71 221.03 42.33 83.08
14 INT16608 Positive_regulation of FFAR1 40 0.37 18.48 3.59 78.40
15 INT5118 Regulation of SST 97 0.62 34.35 51.74 78.40
16 INT181174 Positive_regulation of Regulation of GALT 1 0.07 0.61 0.03 76.44
17 INT1888 Protein_catabolism of F13A1 97 0.99 63.48 14.82 75.00
18 INT181176 Regulation of GALT 2 0.18 1.13 0.16 72.52
19 INT122709 Localization of CYP3A4 16 0.75 5.41 2.38 70.68
20 INT159864 Localization of CYP3A5 2 0.73 0.33 0.52 70.68
21 INT132529 Binding of TAPBP 8 0.47 1.43 0.18 67.88
22 INT55343 Localization of Ros1 39 0.60 34.51 12.5 64.48
23 INT17612 Gene_expression of CRP 676 0.78 580.61 119.03 64.32
24 INT1123 Positive_regulation of CD79A 74 0.70 51.96 7.14 64.32
25 INT24724 Positive_regulation of Gene_expression of SST 11 0.67 7.51 6.12 60.80
26 INT8347 Gene_expression of SST 181 0.78 104.59 65.45 60.16
27 INT132531 Positive_regulation of TAPBP 8 0.49 2.84 1.09 51.48
28 INT181175 Negative_regulation of TAPBP 1 0.35 0.81 0.05 50.32
29 INT443 Localization of POMC 1020 0.81 284.52 443.17 50.00
30 INT6852 Localization of TNF 883 0.81 705.95 270.84 50.00
31 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 50.00
32 INT12082 Localization of IL6 365 0.81 241.78 105.78 50.00
33 INT214 Localization of AVP 370 0.81 208.51 91.09 50.00
34 INT6849 Localization of IL1B 229 0.81 112.56 69.63 50.00
35 INT1199 Positive_regulation of INS 579 0.70 399.64 50.43 50.00
36 INT957 Positive_regulation of GHRH 136 0.70 36.84 40.52 50.00
37 INT8210 Positive_regulation of Gene_expression of INS 188 0.68 146.57 12.83 50.00
38 INT22383 Binding of IL2 59 0.48 39.06 8.56 50.00
39 INT5148 Regulation of CD40LG 25 0.44 21.58 4.05 50.00
40 INT45230 Regulation of CD79A 20 0.44 9.3 1.59 50.00
41 INT44600 Gene_expression of MALT1 6 0.75 6.14 0.42 50.00
42 INT181172 Positive_regulation of MALT1 1 0.01 0.27 0.08 50.00
43 INT181173 Binding of LDHD 1 0.05 0.77 0.03 50.00
44 INT181178 Positive_regulation of NAALADL1 1 0.01 0 0.03 50.00
45 INT255233 Negative_regulation of MCDR1 1 0.07 2.07 0 44.36
46 INT54834 Gene_expression of Col2a1 48 0.72 13.5 9.41 43.36
47 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74 41.84
48 INT9494 Positive_regulation of Gene_expression of Igf1 34 0.67 17.77 6.26 32.32
49 INT8915 Gene_expression of Igf1 199 0.78 78.58 32.51 31.32
50 INT252 Localization of GH1 529 0.80 227.4 122.05 25.60
51 INT69304 Negative_regulation of Il10 47 0.59 36.88 19.79 23.40
52 INT3952 Negative_regulation of ALB 116 0.59 72.18 18.35 21.04
53 INT52732 Negative_regulation of CRP 169 0.59 138.47 40.33 17.20
54 INT153300 Negative_regulation of Gene_expression of CRP 48 0.58 39.97 7.58 17.20
55 INT2542 Localization of Calca 2008 0.81 518.3 1408.65 5.00
56 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 5.00
57 INT4941 Positive_regulation of Oprd1 345 0.70 74.26 304.41 5.00
58 INT16868 Gene_expression of Il6 807 0.78 499.48 256.57 5.00
59 INT6481 Binding of TNF 624 0.48 510.2 214.82 5.00
60 INT11313 Positive_regulation of Il6 526 0.70 331.27 201.59 5.00
61 INT120811 Gene_expression of Gopc 1174 0.59 428.49 150.55 5.00
62 INT9660 Regulation of TNF 363 0.62 312.94 139.99 5.00
63 INT48895 Gene_expression of Il10 333 0.78 221.2 138.52 5.00
64 INT9235 Negative_regulation of Gene_expression of TNF 346 0.59 252.98 118.61 5.00
65 INT90 Localization of Gast 400 0.81 137.67 113 5.00
66 INT914 Positive_regulation of GH1 292 0.69 100.7 84.91 5.00
67 INT15913 Negative_regulation of CYP2D6 174 0.59 22.45 70.91 5.00
68 INT822 Gene_expression of ESR1 529 0.78 302.16 63.64 5.00
69 INT103924 Positive_regulation of Akt1 359 0.69 158.94 60.34 5.00
70 INT14740 Gene_expression of TGFB1 272 0.78 168.48 60.18 5.00
71 INT48891 Positive_regulation of Il10 143 0.70 101.42 56.72 5.00
72 INT52692 Gene_expression of Ptgs2 160 0.78 85.06 55.73 5.00
73 INT49993 Positive_regulation of Gene_expression of Il6 149 0.70 88.07 53.78 5.00
74 INT50405 Negative_regulation of CYP3A4 238 0.59 53.65 51.51 5.00
75 INT921 Regulation of GH1 172 0.60 52.88 51.04 5.00
76 INT531 Gene_expression of GH1 376 0.75 193.45 46.24 5.00
77 INT61619 Gene_expression of IL12A 194 0.77 146.07 41.97 5.00
78 INT3758 Gene_expression of ALB 326 0.78 184.65 38.75 5.00
79 INT9082 Positive_regulation of ESR1 238 0.69 148.51 36.69 5.00
80 INT48896 Positive_regulation of Gene_expression of Il10 73 0.70 43.14 35.5 5.00
81 INT692 Negative_regulation of SST 72 0.59 28.68 34.52 5.00
82 INT114881 Gene_expression of Akt1 227 0.78 102.49 31.81 5.00
83 INT22211 Positive_regulation of CYP3A4 110 0.70 22 28.27 5.00
84 INT3760 Positive_regulation of ALB 142 0.70 87.46 26.7 5.00
85 INT130176 Positive_regulation of Gene_expression of CRP 125 0.66 137.06 25.9 5.00
86 INT122570 Negative_regulation of Akt1 173 0.59 91.44 25.53 5.00
87 INT69322 Negative_regulation of MAPK14 70 0.54 42.92 22.71 5.00
88 INT91891 Gene_expression of Kit 268 0.78 158.89 22.67 5.00
89 INT23257 Regulation of CRP 127 0.62 100.05 21.87 5.00
90 INT112029 Positive_regulation of Pik3r1 90 0.67 38.76 20.95 5.00
91 INT51055 Positive_regulation of TIMP1 103 0.69 50.07 19.86 5.00
92 INT59929 Negative_regulation of CYP2C9 60 0.59 16.33 15.39 5.00
93 INT55740 Gene_expression of Timp1 53 0.75 28.63 13.85 5.00
94 INT114420 Negative_regulation of Pik3r1 67 0.54 34.86 12.82 5.00
95 INT158124 Gene_expression of COL5A2 136 0.69 72.3 12.44 5.00
96 INT8224 Gene_expression of CHGA 73 0.75 53.63 12.31 5.00
97 INT3602 Negative_regulation of Shbg 148 0.53 69.05 11.65 5.00
98 INT85535 Negative_regulation of Gene_expression of Ptgs2 27 0.51 16.04 10.01 5.00
99 INT70134 Negative_regulation of TXK 124 0.23 81.96 9.59 5.00
100 INT62829 Positive_regulation of VCAM1 39 0.70 38.42 9.15 5.00
101 INT51530 Negative_regulation of Adk 11 0.56 3.83 9.07 5.00
102 INT25381 Localization of Csf2 62 0.76 47.48 9.03 5.00
103 INT22798 Regulation of Shbg 64 0.60 26.71 8.76 5.00
104 INT26795 Gene_expression of Mtpn 44 0.62 27.66 8.62 5.00
105 INT97331 Positive_regulation of Timp1 20 0.45 13.32 8.57 5.00
106 INT36798 Gene_expression of Mki67 178 0.77 132 8.24 5.00
107 INT3757 Positive_regulation of Gene_expression of ALB 45 0.69 23.73 6.85 5.00
108 INT172084 Positive_regulation of Binding of TNF 21 0.50 15.31 6.06 5.00
109 INT83119 Negative_regulation of Gene_expression of IL12A 24 0.42 17.52 5.69 5.00
110 INT141146 Gene_expression of Mmp13 18 0.38 8.61 5.54 5.00
111 INT24080 Negative_regulation of Mtor 64 0.37 41.56 5.19 5.00
112 INT156794 Gene_expression of CISH 41 0.58 23.09 5.03 5.00
113 INT18898 Positive_regulation of CHGA 38 0.67 28.99 4.86 5.00
114 INT69215 Gene_expression of Col1a1 38 0.68 17.39 4.77 5.00
115 INT22973 Gene_expression of Col3a1 22 0.42 15.85 4.32 5.00
116 INT146946 Gene_expression of Lyn 16 0.76 8.9 3.75 5.00
117 INT136106 Gene_expression of DNMT3B 30 0.58 8.43 3.7 5.00
118 INT124185 Negative_regulation of Kit 57 0.59 35.43 3.61 5.00
119 INT130295 Gene_expression of Abcg2 21 0.75 9.75 3.42 5.00
120 INT19211 Binding of Shbg 35 0.48 16.29 3.31 5.00
121 INT67719 Positive_regulation of Col1a1 21 0.44 8.87 3.12 5.00
122 INT91173 Gene_expression of Pdgfrb 33 0.65 32.55 3.09 5.00
123 INT55739 Transcription of Timp1 7 0.67 4.72 3 5.00
124 INT77602 Binding of VCAM1 8 0.41 8.66 2.86 5.00
125 INT133038 Binding of DNMT3B 26 0.40 5.97 2.83 5.00
126 INT101246 Gene_expression of Gata6 6 0.68 3.03 2.68 5.00
127 INT113160 Negative_regulation of Jak2 26 0.58 20.3 2.57 5.00
128 INT184063 Positive_regulation of Jak2 17 0.69 10.97 2.37 5.00
129 INT130961 Gene_expression of MADCAM1 4 0.33 5.03 2.28 5.00
130 INT151449 Negative_regulation of Gene_expression of Kit 18 0.45 12.05 2.23 5.00
131 INT47543 Positive_regulation of Chrm3 11 0.38 5.23 2.17 5.00
132 INT70600 Positive_regulation of Exo1 9 0.39 4.36 2.05 5.00
133 INT99572 Localization of Kit 13 0.75 5.23 1.95 5.00
134 INT98469 Positive_regulation of Transcription of Timp1 4 0.45 3.2 1.68 5.00
135 INT146943 Gene_expression of Src 13 0.49 6.65 1.65 5.00
136 INT25384 Positive_regulation of Localization of Csf2 11 0.66 7.81 1.62 5.00
137 INT101412 Negative_regulation of CDAN1 16 0.57 6.41 1.61 5.00
138 INT144019 Negative_regulation of Pdgfrb 21 0.58 14.93 1.26 5.00
139 INT139144 Positive_regulation of Glp2r 5 0.69 2.03 1.26 5.00
140 INT141467 Gene_expression of Glp2r 5 0.77 4.21 1.25 5.00
141 INT164325 Negative_regulation of Abcg2 6 0.39 1.88 1.2 5.00
142 INT67590 Gene_expression of RDBP 9 0.51 5.17 1.1 5.00
143 INT51264 Positive_regulation of TXK 21 0.54 10.69 1.1 5.00
144 INT134822 Gene_expression of Gja1 18 0.72 4.2 1 5.00
145 INT164324 Negative_regulation of Gene_expression of Abcg2 4 0.45 1.03 0.99 5.00
146 INT277920 Binding of MADCAM1 4 0.14 3.11 0.96 5.00
147 INT88000 Gene_expression of LAP 15 0.55 6.94 0.91 5.00
148 INT199563 Negative_regulation of Abl1 38 0.46 21.5 0.87 5.00
149 INT8888 Regulation of Col1a1 4 0.13 1.97 0.86 5.00
150 INT139147 Localization of Glp2r 3 0.80 0.96 0.85 5.00
151 INT85652 Positive_regulation of RDBP 4 0.38 1.76 0.83 5.00
152 INT139146 Positive_regulation of Localization of Glp2r 2 0.67 0.37 0.76 5.00
153 INT241499 Binding of Abl1 23 0.47 8.86 0.75 5.00
154 INT199573 Gene_expression of Abl1 33 0.65 20.79 0.75 5.00
155 INT287087 Localization of EEC1 2 0.61 1.6 0.72 5.00
156 INT171364 Localization of Pdgfrb 6 0.37 4.98 0.68 5.00
157 INT138429 Negative_regulation of Gene_expression of Col3a1 3 0.17 2.51 0.54 5.00
158 INT213789 Phosphorylation of Kit 7 0.69 5.32 0.43 5.00
159 INT125708 Negative_regulation of Col3a1 2 0.16 1.37 0.42 5.00
160 INT154419 Gene_expression of Cdan1 4 0.65 1.79 0.42 5.00
161 INT70884 Localization of Pdgfb 8 0.35 6.22 0.42 5.00
162 INT155490 Binding of Mki67 13 0.19 13.38 0.41 5.00
163 INT141466 Regulation of Glp2r 2 0.45 0.28 0.4 5.00
164 INT336333 Binding of Glp2r 1 0.36 1.5 0.4 5.00
165 INT336330 Regulation of Transcription of Apoc3 1 0.00 0.68 0.35 5.00
166 INT336332 Negative_regulation of Transcription of Apoc3 1 0.01 0.68 0.35 5.00
167 INT336328 Negative_regulation of Apoc3 1 0.01 0.67 0.35 5.00
168 INT336326 Transcription of Apoc3 1 0.01 0.62 0.35 5.00
169 INT336324 Regulation of Negative_regulation of Apoc3 1 0.00 0.68 0.35 5.00
170 INT36797 Regulation of Mki67 13 0.24 8.76 0.3 5.00
171 INT200806 Binding of EEC1 6 0.39 4.24 0.29 5.00
172 INT336325 Phosphorylation of Glp2r 1 0.61 0.5 0.28 5.00
173 INT144021 Binding of Pdgfrb 9 0.37 5.53 0.28 5.00
174 INT277706 Negative_regulation of MAP2K7 1 0.05 0.77 0.24 5.00
175 INT180599 Gene_expression of EEC1 5 0.63 2.73 0.23 5.00
176 INT241498 Regulation of Abl1 8 0.32 6.46 0.22 5.00
177 INT157603 Positive_regulation of Gene_expression of Mmp13 3 0.16 0.91 0.21 5.00
178 INT185093 Binding of H2AFB3 1 0.01 2.8 0.2 5.00
179 INT199561 Positive_regulation of Gene_expression of Abl1 8 0.36 4.77 0.16 5.00
180 INT200802 Regulation of Jak2 5 0.61 2.86 0.16 5.00
181 INT241037 Regulation of Col3a1 2 0.05 1.94 0.14 5.00
182 INT114110 Negative_regulation of EEC1 2 0.37 2.35 0.12 5.00
183 INT209072 Positive_regulation of Positive_regulation of CHGA 1 0.45 0.82 0.12 5.00
184 INT241504 Negative_regulation of Aurka 2 0.09 1.54 0.11 5.00
185 INT241512 Phosphorylation of Abl1 4 0.59 2.68 0.09 5.00
186 INT336329 Negative_regulation of Glp2r 1 0.42 0.59 0.09 5.00
187 INT241515 Negative_regulation of Phosphorylation of Abl1 3 0.30 1.36 0.09 5.00
188 INT175415 Negative_regulation of COX10 5 0.07 3.33 0.08 5.00
189 INT336327 Transcription of Glp2r 1 0.66 0.64 0.07 5.00
190 INT336334 Positive_regulation of Gene_expression of Glp2r 1 0.39 0.87 0.07 5.00
191 INT336316 Gene_expression of Dyrk1a 1 0.04 0.27 0.05 5.00
192 INT308287 Positive_regulation of HPN 1 0.39 0.48 0.05 5.00
193 INT241509 Negative_regulation of Gene_expression of Lyn 2 0.20 1.02 0.05 5.00
194 INT241507 Positive_regulation of Abl1 5 0.40 2.69 0.05 5.00
195 INT241506 Localization of Abl1 2 0.54 2.37 0.04 5.00
196 INT287085 Negative_regulation of Myh9 1 0.21 0.6 0.03 5.00
197 INT241510 Negative_regulation of Phosphorylation of Kit 3 0.31 2.06 0.03 5.00
198 INT225256 Positive_regulation of Gene_expression of Src 3 0.20 0.75 0 5.00
199 INT287083 Binding of Vamp3 1 0.14 1.58 0 5.00
200 INT255236 Regulation of MCDR1 1 0.10 0.06 0 5.00
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