D:Sickle Cell Anemia

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Disease Term
Synonyms Anemia Sickle Cell, ANEMIAS SICKLE CELL, Anti Sickling, Disease Hemoglobin S, DISEASES HEMOGLOBIN S, DREPANOCYTIC ANAEMIA, Drepanocytic Anemia, Haemoglobin C Disease, HAEMOGLOBIN E DISEASE, HAEMOGLOBIN S C DISEASE, Hb S Disease
Documents 1788
Hot Single Events 200
Hot Interactions 27

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Sickle Cell Anemia. They are ordered first by their relevance to Sickle Cell Anemia and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT191590 Binding of AMBP and Arsb 1 0.00 1.82 0.04 100.00
2 INT8771 EPO Positive_regulation of HBG1 1 0.52 0.73 0 99.36
3 INT286898 Binding of HBM and IL6 1 0.01 1.09 0.14 99.14
4 INT286900 Binding of HBM and PDGFA 1 0.04 1.08 0.14 99.14
5 INT286901 Binding of HBM and VEGFA 1 0.05 1.08 0.14 99.14
6 INT264269 Binding of ANC and Darc 1 0.09 1.47 0.52 93.76
7 INT286899 Binding of IL6 and CCL2 1 0.03 0.92 0.08 91.24
8 INT149223 Binding of PHC3 and Suds3 1 0.03 0.44 0.07 91.12
9 INT149222 Binding of Fzd5 and Suds3 1 0.02 0.44 0.07 91.12
10 INT286902 Binding of PDGFA and VEGFA 1 0.24 1.1 0 87.92
11 INT96102 Binding of TAT and Selp 1 0.04 0.7 0.3 87.68
12 INT96082 Binding of SELP and TAT 1 0.40 0.69 0.3 87.68
13 INT96099 Binding of TAT and F2 1 0.01 0.68 0.29 87.68
14 INT96096 Binding of Serpinc1 and Selp 1 0.00 0.69 0.3 86.64
15 INT96101 Binding of SELP and Serpinc1 1 0.01 0.69 0.29 86.64
16 INT96093 Binding of Serpinc1 and F2 1 0.00 0.68 0.29 86.64
17 INT96103 Binding of PPBP and Selp 1 0.00 1.22 0.46 86.28
18 INT96095 Binding of Selp and Pf4 1 0.01 1.2 0.45 86.28
19 INT96094 Binding of Selp and F2 1 0.00 0.67 0.29 86.28
20 INT96083 Binding of PPBP and SELP 1 0.02 1.21 0.46 85.80
21 INT96097 Binding of SELP and Pf4 1 0.13 1.2 0.45 85.80
22 INT96100 Binding of SELP and F2 1 0.01 0.67 0.29 85.80
23 INT118300 Vwf Positive_regulation of Crp 1 0.00 0.87 0.3 84.60
24 INT160445 Tpsab1 Positive_regulation of Gene_expression of SPG21 1 0.48 0.96 0.48 82.32
25 INT160444 Tpsab1 Positive_regulation of Gene_expression of CEL 1 0.48 0.96 0.48 82.32
26 INT96089 Binding of F2 and Pf4 1 0.00 1.31 0.56 82.08
27 INT96098 Binding of PPBP and F2 1 0.00 1.31 0.56 82.08
28 INT72311 Binding of reticulocyte alpha 4 beta 1 and Vcam1 1 0.00 0.33 0.13 76.24
29 INT58480 Agpat1 Regulation of TF 1 0.00 0.46 0.4 75.76
30 INT58481 Crp Regulation of TF 1 0.01 0.46 0.4 75.76
31 INT72312 IL8 Positive_regulation of reticulocyte alpha 4 beta 1 1 0.00 0.3 0.12 75.00
32 INT310412 Binding of CP and TF 1 0.14 1.66 0.13 54.80
33 INT162508 Binding of ITGA2B and ITPR1 1 0.02 0.05 0 54.60
34 INT162510 Binding of ITPR1 and HPSE 1 0.02 0.05 0 54.60
35 INT318329 Binding of HBA1 and HBB 1 0.02 1 0 53.76
36 INT230455 FOXG1 Negative_regulation of HBS1L 1 0.02 1.73 0.18 50.00
37 INT126944 Binding of PKD2 and Pkd1 2 0.08 2.09 0.19 42.96
38 INT317833 Nlrp3 Positive_regulation of Localization of Il1 1 0.06 1.38 0.26 13.92
39 INT175329 Binding of ICAM1 and ITGAL 14 0.18 10.06 2.81 5.00
40 INT351281 AP1M2 Regulation of NCOR2 1 0.00 0.85 1.9 5.00
41 INT208991 Binding of CALM1 and Ca2 10 0.06 1.34 1.55 5.00
42 INT317836 Binding of Fibp and Pycard 1 0.00 2.68 0.98 5.00
43 INT54972 Binding of EDNRA and EDNRB 7 0.52 3.31 0.97 5.00
44 INT182814 Binding of ICAM1 and PECAM1 2 0.02 3.32 0.77 5.00
45 INT170127 Binding of ITGAL and PECAM1 2 0.01 2.71 0.75 5.00
46 INT317832 Binding of Mefv and Il1 1 0.03 3.89 0.7 5.00
47 INT278827 Binding of EDN1 and EDNRB 3 0.17 2.7 0.67 5.00
48 INT178097 Binding of EDN1 and EDNRA 7 0.21 5.97 0.62 5.00
49 INT182819 Binding of CD63 and PECAM1 1 0.00 1.63 0.61 5.00
50 INT182815 Binding of CD63 and ICAM1 1 0.00 1.63 0.61 5.00
51 INT315334 Binding of CYP3A4 and CDIPT 3 0.04 0.85 0.59 5.00
52 INT144035 IL6 Positive_regulation of STAT3 4 0.31 2.58 0.56 5.00
53 INT278824 Positive_regulation of Binding of EDNRA and EDNRB 1 0.12 1.65 0.53 5.00
54 INT278819 EDNRA Negative_regulation of Binding of EDNRA and EDNRB 1 0.04 1.65 0.53 5.00
55 INT182813 EEF1A2 Negative_regulation of ITGAL 1 0.10 1.53 0.51 5.00
56 INT278825 Positive_regulation of Binding of EDN1 and EDNRB 3 0.16 1.24 0.49 5.00
57 INT317834 Binding of Pstpip1 and Il1 1 0.00 2.03 0.48 5.00
58 INT278379 Binding of Pstpip1 and Mefv 3 0.03 2.02 0.48 5.00
59 INT277985 Epo Positive_regulation of Epc1 1 0.03 1.36 0.36 5.00
60 INT278820 EDNRA Negative_regulation of Binding of EDN1 and EDNRB 1 0.03 1.1 0.35 5.00
61 INT317835 Nlrp3 Positive_regulation of Il18 1 0.08 1.49 0.31 5.00
62 INT182817 EEF1A2 Positive_regulation of BMP2 1 0.26 1.62 0.28 5.00
63 INT354544 Avp Positive_regulation of ADCY1 1 0.24 2.23 0.22 5.00
64 INT306178 Rhoa Positive_regulation of Rock2 2 0.40 1.04 0.21 5.00
65 INT182816 EEF1A2 Negative_regulation of CRP 1 0.28 1.84 0.21 5.00
66 INT264270 Binding of ANC and Pbrgcsf1 1 0.01 0.15 0.21 5.00
67 INT252357 Binding of THBS1 and Cd36 2 0.01 2.4 0.21 5.00
68 INT317831 Binding of Mefv and Nlrx1 1 0.00 1.77 0.2 5.00
69 INT102743 Binding of SEPT5 and Vwf 1 0.01 0.35 0.2 5.00
70 INT244299 FFAR1 Positive_regulation of PTH1R 1 0.00 0.4 0.2 5.00
71 INT173430 Binding of FLT4 and VEGFA 10 0.25 9.38 0.19 5.00
72 INT278817 EDNRA Negative_regulation of Binding of EDN1 and EDNRA 1 0.02 0.55 0.18 5.00
73 INT278818 EDNRA Negative_regulation of Binding of EDNRB and EDNRB 1 0.06 0.55 0.18 5.00
74 INT298641 PPARA Regulation of STAT3 1 0.23 0.98 0.16 5.00
75 INT277990 Binding of Cd3e and Hand1 1 0.01 0.5 0.16 5.00
76 INT278828 Positive_regulation of Binding of EDN1 and EDNRA 1 0.06 0.51 0.15 5.00
77 INT298639 GDE1 Negative_regulation of AKT1 1 0.00 1.14 0.14 5.00
78 INT277984 Negative_regulation of Epo Positive_regulation of Localization of Ptprc 1 0.02 0.77 0.12 5.00
79 INT277986 Negative_regulation of Epo Positive_regulation of Localization of Cd34 1 0.08 0.77 0.12 5.00
80 INT277988 Csf3 Positive_regulation of Epc1 1 0.00 0.51 0.11 5.00
81 INT277987 Regulation of Csf3 Positive_regulation of Epc1 1 0.00 0.51 0.11 5.00
82 INT298634 Binding of IL6 and STAT3 1 0.04 1.41 0.08 5.00
83 INT268679 Binding of HDAC1 and NCOR2 3 0.17 2.8 0.07 5.00
84 INT89430 Binding of ICAM4 and ITGA4 1 0.05 0.48 0.06 5.00
85 INT339583 Binding of ABCA1 and RPE 1 0.03 1.38 0.05 5.00
86 INT298638 IL6 Positive_regulation of IL6R 1 0.00 0.9 0.05 5.00
87 INT339587 Positive_regulation of Binding of ABCA1 and RPE 1 0.04 1.38 0.05 5.00
88 INT348715 Positive_regulation of Binding of Ca2 and Mylk 1 0.02 0.47 0.05 5.00
89 INT348716 Binding of Ca2 and Mylk 1 0.02 0.47 0.05 5.00
90 INT298635 PPARA Negative_regulation of Localization of ZDHHC2 1 0.01 0.21 0.05 5.00
91 INT298683 ecs Positive_regulation of Gene_expression of VEGFA 1 0.02 1.41 0.04 5.00
92 INT213207 Negative_regulation of ASAP2 Negative_regulation of PVR 1 0.01 0.45 0.04 5.00
93 INT298637 ZDHHC2 Negative_regulation of Gene_expression of VEGFA 1 0.01 0.27 0.04 5.00
94 INT213206 ASAP2 Negative_regulation of PVR 1 0.01 0.44 0.04 5.00
95 INT284916 IL1RN Negative_regulation of HDAC4 1 0.00 1.66 0.03 5.00
96 INT298633 STAT3 Regulation of MCL1 1 0.04 0.85 0.03 5.00
97 INT298640 IL6R Positive_regulation of STAT3 1 0.01 0.73 0.03 5.00
98 INT353795 Binding of Cd320 and Apob 1 0.08 0.82 0 5.00
99 INT298684 ecs Positive_regulation of Gene_expression of KDR 1 0.01 1.2 0 5.00
100 INT339582 AMD1 Regulation of C1QTNF5 1 0.07 2 0 5.00
101 INT354566 F2 Positive_regulation of PRNP 1 0.00 0.05 0 5.00
102 INT353798 Binding of Hdl1 and Apob 1 0.01 0.82 0 5.00
103 INT284919 XRCC6 Negative_regulation of BAX 1 0.01 0.64 0 5.00
104 INT284920 Binding of HDAC1 and NCOR1 1 0.03 0.13 0 5.00
105 INT282630 Binding of CISH and UGT2B17 1 0.04 0 0 5.00
106 INT89432 Binding of LAMB2 and IGSF11 1 0.01 0.47 0 5.00
107 INT284918 RUNX1T1 Regulation of DNMT1 1 0.21 1.09 0 5.00
108 INT353799 Binding of Cd320 and Hdl1 1 0.03 0.83 0 5.00
109 INT284917 RUNX1T1 Regulation of HDAC9 1 0.19 1.09 0 5.00
110 INT284914 Binding of HDAC1 and NCK1 1 0.00 0.13 0 5.00
111 INT89431 Binding of LAMB2 and BCAM 1 0.05 0.47 0 5.00
112 INT144032 STAT3 Regulation of BCL2 2 0.07 0.86 0 5.00
113 INT353802 Binding of APOE and Apob 1 0.05 0.83 0 5.00
114 INT339581 Binding of TIMP1 and TIMP3 1 0.30 0.54 0 5.00
115 INT318132 Binding of ATRX and HBE1 1 0.00 1.47 0 5.00
116 INT283062 ERCC8 Positive_regulation of CFH 1 0.02 1.88 0 5.00
117 INT348723 ED Positive_regulation of PTEN 1 0.04 1.3 0 5.00
118 INT339580 TIMP3 Positive_regulation of ABCA1 1 0.16 0.73 0 5.00
119 INT353801 Binding of APOE and Cd320 1 0.22 0.83 0 5.00
120 INT339585 Binding of AMD1 and MDM1 1 0.06 2.02 0 5.00
121 INT353796 Binding of Ldlr and Apob 1 0.06 0.82 0 5.00
122 INT182818 EEF1A2 Negative_regulation of STAR 1 0.01 1.48 0 5.00
123 INT217922 Binding of GSTA4 and SULT1D1P 1 0.29 0 0 5.00
124 INT284915 Binding of CDKN2B and HIST2H3C 1 0.05 0.43 0 5.00
125 INT298632 STAT3 Positive_regulation of MIR21 1 0.03 0.84 0 5.00
126 INT283061 Binding of ERCC8 and LDLR 1 0.00 0.44 0 5.00
127 INT353804 Binding of APOE and Ldlr 1 0.16 0.84 0 5.00
128 INT285042 Dbi Regulation of Gene_expression of Rho 1 0.01 0 0 5.00
129 INT285047 WTS Regulation of Gene_expression of Rho 1 0.02 0 0 5.00
130 INT217923 Positive_regulation of Binding of GSTA4 and SULT1D1P 1 0.37 0 0 5.00
131 INT339586 TIMP3 Positive_regulation of RPE 1 0.16 0.72 0 5.00
132 INT284995 Binding of HDAC1 and Sin3a 1 0.00 0.13 0 5.00
133 INT353797 Binding of Ldlr and Trf 1 0.04 0.19 0 5.00
134 INT353800 Binding of Ldlr and Cd320 1 0.29 0.83 0 5.00
135 INT292784 LPA Positive_regulation of Rbm19 1 0.01 0.06 0 5.00
136 INT353803 Binding of APOE and Hdl1 1 0.01 0.83 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Sickle Cell Anemia. They are ordered first by their pain relevance and then by number of times they were reported in Sickle Cell Anemia. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT4596 Positive_regulation of SCD 18 0.42 22.59 3.26 100.00
2 INT3915 Gene_expression of SCD 25 0.57 13.94 6 100.00
3 INT4465 Gene_expression of CEL 116 0.77 98.35 23.58 100.00
4 INT28950 Positive_regulation of Gene_expression of IGF1 99 0.69 46.9 16.47 100.00
5 INT73611 Negative_regulation of SCD 15 0.37 26.67 3.71 100.00
6 INT3854 Binding of SCD 16 0.41 11.14 3.7 100.00
7 INT26073 Gene_expression of Scd1 17 0.70 9.17 0.47 100.00
8 INT5865 Positive_regulation of Localization of Gh 282 0.69 84.86 93.5 100.00
9 INT1735 Gene_expression of HSD11B1 199 0.75 257.87 11.5 100.00
10 INT16808 Binding of Scd1 5 0.00 7.18 0.33 100.00
11 INT153732 Positive_regulation of Gene_expression of SCD 9 0.47 3.28 0.29 100.00
12 INT4464 Localization of CEL 21 0.80 8.09 3.88 100.00
13 INT35366 Binding of AR 87 0.47 30.52 8.9 100.00
14 INT3647 Positive_regulation of Gene_expression of F13A1 20 0.41 15.71 5.02 100.00
15 INT155335 Negative_regulation of Positive_regulation of SCD 1 0.30 1.78 0.39 100.00
16 INT170743 Negative_regulation of Gene_expression of Scd1 2 0.38 1.57 0 100.00
17 INT121335 Localization of SCD 10 0.68 6.81 1.51 100.00
18 INT170734 Positive_regulation of Gene_expression of Scd1 5 0.48 5.87 0.13 100.00
19 INT115695 Positive_regulation of ATXN1 2 0.22 1.23 0.98 100.00
20 INT228685 Negative_regulation of Gene_expression of SCD 2 0.26 1.64 0.38 100.00
21 INT114504 Positive_regulation of Scd1 10 0.48 3.77 0.8 100.00
22 INT169274 Protein_catabolism of SCD 1 0.63 1.29 0.57 100.00
23 INT310528 Negative_regulation of Positive_regulation of HRASLS 1 0.01 1.6 0.18 100.00
24 INT170740 Localization of Scd1 1 0.17 0.99 0 100.00
25 INT49377 Negative_regulation of Scd1 11 0.49 9.84 1.88 100.00
26 INT4597 Regulation of SCD 5 0.39 2.25 0.5 100.00
27 INT170284 Gene_expression of Arsb 9 0.65 9.12 0.63 100.00
28 INT18995 Binding of CEL 23 0.47 14.46 4.5 100.00
29 INT67604 Gene_expression of SERPINC1 14 0.67 11.47 1.72 100.00
30 INT174100 Gene_expression of YWHAE 14 0.31 12.42 0.08 100.00
31 INT169020 Phosphorylation of Bcam 1 0.01 0.6 0.16 99.92
32 INT169019 Negative_regulation of Phosphorylation of Bcam 1 0.00 0.6 0.16 99.92
33 INT1497 Negative_regulation of Gh 415 0.59 192.95 74.71 99.90
34 INT1498 Gene_expression of Gh 521 0.75 220.84 81.16 99.88
35 INT40084 Binding of HBS1L 8 0.36 9.15 0.69 99.88
36 INT2978 Gene_expression of Tbxa2r 76 0.77 28.4 21.27 99.88
37 INT16220 Negative_regulation of Regulation of Gh 13 0.42 3.59 4.33 99.86
38 INT1060 Negative_regulation of Pla2g1b 50 0.57 22.91 18.12 99.84
39 INT10838 Positive_regulation of IL8 381 0.70 295.51 101.62 99.84
40 INT110039 Positive_regulation of Nppb 38 0.53 34.54 2.88 99.84
41 INT90939 Positive_regulation of Eng 9 0.64 4.62 0.57 99.84
42 INT306940 Positive_regulation of HAMP 3 0.49 5.06 0.36 99.84
43 INT310530 Positive_regulation of Gene_expression of HAMP 3 0.49 4.16 0.28 99.84
44 INT108523 Regulation of Gene_expression of Hbb-b1 1 0.02 0.61 0.1 99.84
45 INT60526 Gene_expression of IL10 449 0.78 292.71 107.84 99.84
46 INT17035 Positive_regulation of TFPI 55 0.61 34.88 14.18 99.84
47 INT36449 Negative_regulation of G6PD 74 0.59 54.15 8.85 99.82
48 INT94827 Gene_expression of HBS1L 24 0.67 26.11 1.61 99.80
49 INT98068 Gene_expression of SCN2A 19 0.75 14.42 3.31 99.80
50 INT92084 Negative_regulation of HPFH 2 0.42 0.75 0.38 99.80
51 INT99001 Negative_regulation of Selp 23 0.59 16.68 4.74 99.80
52 INT79464 Binding of HBA2 2 0.47 1.75 0.09 99.78
53 INT47939 Gene_expression of Selp 171 0.76 87.54 39.03 99.76
54 INT36450 Regulation of Negative_regulation of G6PD 2 0.40 1.59 0.46 99.76
55 INT44558 Positive_regulation of PDXP 6 0.35 3.65 1.22 99.74
56 INT170741 Positive_regulation of Ccl27a 1 0.03 1.17 0.05 99.70
57 INT170733 Positive_regulation of Gene_expression of Ccl27a 1 0.03 1.17 0.05 99.70
58 INT50595 Positive_regulation of HRASLS 16 0.49 9.65 4.24 99.70
59 INT17086 Binding of HSD11B1 84 0.47 122.28 6.16 99.68
60 INT210390 Binding of PDGFA 12 0.36 6.78 0.63 99.68
61 INT67179 Negative_regulation of Binding of F2 3 0.41 2.23 0.45 99.68
62 INT56374 Gene_expression of AMBP 34 0.54 35.85 6.25 99.68
63 INT1894 Negative_regulation of Localization of Gh 168 0.58 64.12 43.56 99.66
64 INT1530 Regulation of Gh 382 0.61 115.96 112.47 99.66
65 INT28952 Negative_regulation of Gene_expression of IGF1 75 0.58 41.11 12.32 99.64
66 INT2843 Gene_expression of Epo 100 0.78 62.01 14.66 99.64
67 INT48406 Gene_expression of Icam1 277 0.78 238.28 81.71 99.64
68 INT63169 Positive_regulation of Gene_expression of Selp 35 0.69 21.95 7.16 99.64
69 INT5650 Gene_expression of Mpo 117 0.77 80.27 26.42 99.64
70 INT29740 Gene_expression of ANG 55 0.78 24.53 9.86 99.64
71 INT58766 Gene_expression of ANGPT2 41 0.67 21.65 4.82 99.64
72 INT16996 Gene_expression of PRTN3 113 0.75 85.61 22.57 99.64
73 INT85719 Gene_expression of Bcar3 1 0.00 0.27 0.1 99.64
74 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65 99.62
75 INT21610 Positive_regulation of ANGPT2 23 0.41 13.28 3.03 99.60
76 INT95117 Gene_expression of PDGFA 71 0.71 51.17 6.9 99.56
77 INT15540 Positive_regulation of PDGFA 24 0.47 19.01 2.5 99.56
78 INT10899 Positive_regulation of Gene_expression of Edn1 32 0.70 24.88 7.65 99.54
79 INT170737 Localization of Acsl1 5 0.20 3.51 0.38 99.52
80 INT170736 Gene_expression of Ccl27a 3 0.48 2.05 0.47 99.50
81 INT2393 Positive_regulation of Mb 174 0.69 93.59 26.79 99.48
82 INT9106 Positive_regulation of F3 8 0.22 4.92 1.85 99.48
83 INT47629 Positive_regulation of Bdh1 2 0.44 0.77 0.13 99.48
84 INT1893 Localization of Gh 1041 0.79 340.23 256.58 99.46
85 INT11313 Positive_regulation of Il6 526 0.70 331.27 201.59 99.46
86 INT58301 Positive_regulation of Mpo 87 0.70 80.19 23.99 99.46
87 INT49993 Positive_regulation of Gene_expression of Il6 149 0.70 88.07 53.78 99.46
88 INT50932 Positive_regulation of Positive_regulation of Il6 36 0.69 24.9 16.12 99.46
89 INT82932 Transcription of AR 14 0.67 5.75 1.34 99.44
90 INT166835 Regulation of HBB 1 0.02 1.08 0.08 99.44
91 INT86024 Gene_expression of PPARA 736 0.78 497.93 91.14 99.44
92 INT1734 Negative_regulation of HSD11B1 116 0.57 125.13 10.52 99.42
93 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 99.40
94 INT16960 Gene_expression of Crp 166 0.76 116.21 34.07 99.40
95 INT1926 Positive_regulation of PLAT 54 0.66 31.42 6.49 99.40
96 INT13240 Gene_expression of TF 94 0.76 57.81 10.99 99.40
97 INT90938 Gene_expression of Eng 48 0.72 15.76 1.24 99.38
98 INT103154 Gene_expression of FLT1 138 0.76 58.5 7.41 99.38
99 INT129534 Gene_expression of Nppb 19 0.58 23.68 1.6 99.36
100 INT4553 Binding of G6PD 7 0.37 3 0.44 99.32
101 INT4103 Regulation of G6PD 6 0.60 0.78 0.82 99.32
102 INT49105 Gene_expression of Vcam1 157 0.78 157.27 43.01 99.28
103 INT49104 Positive_regulation of Gene_expression of Vcam1 30 0.69 36.52 7.64 99.28
104 INT9682 Positive_regulation of IGF1 238 0.70 120.03 26.36 99.28
105 INT8773 Gene_expression of HBG1 58 0.76 37.6 4.59 99.28
106 INT8772 Positive_regulation of Gene_expression of HBG1 16 0.68 6.93 0.95 99.28
107 INT4047 Binding of F13A1 105 0.43 66.54 11.81 99.28
108 INT8866 Positive_regulation of TAT 30 0.67 18.06 5.57 99.28
109 INT72129 Positive_regulation of Positive_regulation of IGF1 11 0.50 4.61 1.05 99.28
110 INT16868 Gene_expression of Il6 807 0.78 499.48 256.57 99.28
111 INT48444 Localization of Csf3 28 0.72 14.85 2.11 99.28
112 INT3765 Positive_regulation of Actvty1 8 0.06 23.53 7.37 99.28
113 INT152037 Regulation of Localization of Csf3 1 0.18 0.74 0.09 99.28
114 INT67424 Positive_regulation of Gene_expression of Selp 36 0.68 17.08 7.95 99.28
115 INT211968 Localization of Best1 11 0.40 9.33 0.38 99.28
116 INT5409 Negative_regulation of G6pd 33 0.57 29.21 7.64 99.24
117 INT41892 Gene_expression of HBM 48 0.64 28.32 5.64 99.24
118 INT41891 Positive_regulation of Gene_expression of HBM 3 0.12 1.19 0.21 99.24
119 INT102585 Positive_regulation of Gdf15 19 0.69 14.78 3.21 99.24
120 INT32580 Gene_expression of C4B 24 0.75 17.95 7.75 99.16
121 INT99688 Negative_regulation of Gene_expression of VEGFA 274 0.58 201.8 31.1 99.16
122 INT95118 Negative_regulation of Gene_expression of PDGFA 4 0.54 5.03 0.76 99.16
123 INT204156 Gene_expression of HAMP 7 0.75 8.1 0.94 99.12
124 INT73502 Positive_regulation of IL10 154 0.69 124.87 43.5 99.12
125 INT49141 Gene_expression of Selp 157 0.78 85.22 24.78 99.10
126 INT189272 Binding of KRT122P 3 0.36 1.77 0.16 99.10
127 INT10832 Gene_expression of IL8 1050 0.78 698.72 270 99.08
128 INT11381 Positive_regulation of IL1B 330 0.70 209.31 100.9 99.06
129 INT49103 Positive_regulation of Vcam1 71 0.69 59.52 19.85 99.00
130 INT156351 Positive_regulation of Flt1 22 0.51 20.05 0.91 99.00
131 INT613 Gene_expression of Alb 268 0.78 149.84 42.78 99.00
132 INT36108 Positive_regulation of ACP1 2 0.41 0.82 0.13 98.96
133 INT27519 Positive_regulation of HPFH 1 0.01 0.19 0.1 98.96
134 INT96136 Binding of hb 12 0.34 10.21 1.68 98.92
135 INT117455 Negative_regulation of Adamts13 7 0.53 9.69 0.95 98.90
136 INT136088 Gene_expression of Adamts13 1 0.48 0.29 0.24 98.90
137 INT155 Positive_regulation of Prl 1233 0.70 317.93 457.82 98.88
138 INT17802 Transcription of Edn1 6 0.24 6.31 1.18 98.88
139 INT170744 Positive_regulation of Transcription of Edn1 2 0.20 1.3 0.1 98.88
140 INT14997 Positive_regulation of FPR1 21 0.66 9.82 13.2 98.86
141 INT143127 Positive_regulation of FLT1 44 0.66 21.7 1.92 98.84
142 INT49487 Gene_expression of Sele 65 0.76 68.11 19.41 98.84
143 INT308962 Regulation of SLC7A7 3 0.16 1.2 0.18 98.84
144 INT236072 Binding of DARC 8 0.03 6.01 0.03 98.84
145 INT17401 Gene_expression of IGF1 475 0.78 232.18 62.07 98.80
146 INT12135 Gene_expression of PLEK 62 0.75 34.13 12.47 98.80
147 INT899 Gene_expression of F13A1 122 0.70 78.02 16.26 98.80
148 INT2442 Localization of Mb 38 0.80 24.74 6.33 98.76
149 INT47630 Localization of Bdh1 1 0.04 0.33 0.1 98.76
150 INT14962 Gene_expression of Pf4 27 0.76 22.48 10.88 98.72
151 INT108524 Gene_expression of Hbb-b1 2 0.60 0.91 1.59 98.72
152 INT49130 Positive_regulation of IGFBP3 49 0.63 27.55 4.78 98.68
153 INT281429 Regulation of Gene_expression of FTL 1 0.22 1.27 0.15 98.68
154 INT76573 Negative_regulation of Vcam1 26 0.58 24.36 9.84 98.60
155 INT96084 Binding of Selp 12 0.48 8.41 2.16 98.60
156 INT188317 Positive_regulation of Gene_expression of PDGFA 15 0.46 12.7 0.91 98.60
157 INT22445 Binding of Pax1 2 0.31 0.52 0.12 98.60
158 INT310529 Positive_regulation of MDFIC 1 0.05 6.21 0.52 98.58
159 INT4463 Regulation of SCN2A 3 0.44 0.78 0.3 98.58
160 INT195213 Positive_regulation of Gene_expression of HBS1L 4 0.15 3.5 0.16 98.54
161 INT3593 Gene_expression of ADRA1D 70 0.75 29.48 20.87 98.52
162 INT281428 Gene_expression of FTL 1 0.49 1.26 0.15 98.52
163 INT310522 Regulation of Transcription of HAMP 1 0.60 1.36 0.05 98.50
164 INT113462 Localization of HPV18I2 1 0.58 1.42 0.06 98.48
165 INT32579 Binding of C4B 14 0.36 14.99 7.79 98.46
166 INT2339 Positive_regulation of CB 30 0.29 10.68 9.12 98.44
167 INT20280 Positive_regulation of Esr1 32 0.69 18.37 5.69 98.44
168 INT9079 Gene_expression of PPBP 52 0.75 31.2 21.52 98.40
169 INT49142 Gene_expression of SELP 94 0.75 54.61 11.64 98.40
170 INT50530 Binding of MDFIC 2 0.17 1.88 0.38 98.40
171 INT158678 Positive_regulation of Lta4h 2 0.33 0.55 0.55 98.36
172 INT17855 Binding of G6pd 4 0.34 1.42 0.8 98.36
173 INT724 Negative_regulation of Alb 151 0.59 93.57 29.65 98.34
174 INT3098 Positive_regulation of Epo 46 0.70 28.27 7 98.32
175 INT76336 Negative_regulation of PDE5A 192 0.59 112.02 20.09 98.32
176 INT297528 Transcription of HAMP 3 0.69 3.64 0.5 98.30
177 INT11659 Gene_expression of COL2A1 164 0.78 78.49 22.58 98.28
178 INT7205 Positive_regulation of HBG1 65 0.69 40.35 6.37 98.24
179 INT15872 Positive_regulation of EPO 74 0.70 45.35 6.67 98.24
180 INT71965 Gene_expression of Beta-s 1 0.05 0.17 0.06 98.24
181 INT11636 Positive_regulation of SERPINE1 85 0.69 68.73 14.8 98.22
182 INT67181 Positive_regulation of Positive_regulation of SERPINE1 3 0.49 3.02 0.14 98.22
183 INT128406 Gene_expression of Pax1 11 0.60 7.18 5.91 98.20
184 INT35104 Positive_regulation of GC 6 0.11 4.99 1.08 98.20
185 INT64676 Gene_expression of ANXA5 11 0.75 13.48 2.11 98.18
186 INT10915 Gene_expression of ITGAM 164 0.78 92.42 29.78 98.16
187 INT3816 Gene_expression of Ahr 13 0.65 7.51 1.31 98.16
188 INT153731 Positive_regulation of Gene_expression of Ahr 2 0.32 2 0.28 98.16
189 INT21726 Gene_expression of Tfrc 10 0.74 7.38 2.36 98.12
190 INT11042 Localization of Tbxa2r 26 0.76 10.15 7.24 98.12
191 INT22112 Positive_regulation of Localization of TNF 164 0.70 115.66 52.18 98.04
192 INT9408 Positive_regulation of Crp 296 0.69 242.27 57.35 97.96
193 INT545 Binding of GC 15 0.45 10.74 3.47 97.92
194 INT352038 Regulation of Gene_expression of SCN2A 1 0.19 1.39 0 97.92
195 INT11071 Positive_regulation of PPBP 43 0.68 26.85 13.43 97.90
196 INT11069 Positive_regulation of Pf4 35 0.68 27.7 13.96 97.90
197 INT25449 Positive_regulation of Gene_expression of PPBP 5 0.46 3.77 2.57 97.90
198 INT63170 Positive_regulation of Selp 27 0.68 24.1 6.3 97.90
199 INT33567 Gene_expression of CALM1 139 0.67 48.85 56.14 97.84
200 INT23191 Gene_expression of HDLCQ1 13 0.60 14.39 1.58 97.84
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