D:Siderosis

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pChart

Disease Term
Synonyms Sideroses
Documents 40
Hot Single Events 5
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Siderosis. They are ordered first by their relevance to Siderosis and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT75355 Negative_regulation of GCG Regulation of Gh 1 0.01 1.26 0.18 65.00
2 INT75356 GCG Regulation of Gh 1 0.01 1.25 0.18 65.00
3 INT323855 IL6 Positive_regulation of Positive_regulation of TNF 1 0.04 1.03 0.31 5.00
4 INT296372 Binding of IDUA and ACD 1 0.03 2.72 0.23 5.00
5 INT186502 Binding of AMELX and HLA-A 1 0.00 0.71 0 5.00
6 INT318132 Binding of ATRX and HBE1 1 0.00 1.47 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Siderosis. They are ordered first by their pain relevance and then by number of times they were reported in Siderosis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT232405 Binding of DFP 1 0.27 2.4 0.03 93.92
2 INT323860 Positive_regulation of Protein_catabolism of HBM 1 0.01 1.03 0.15 93.68
3 INT323861 Protein_catabolism of HBG2 1 0.19 1.01 0.14 90.88
4 INT207229 Protein_catabolism of HBM 4 0.02 1.52 0.17 87.04
5 INT42176 Gene_expression of DFP 2 0.39 3.71 1.03 82.04
6 INT42583 Protein_catabolism of ELANE 8 0.89 4.33 2.11 63.68
7 INT2609 Localization of ELANE 111 0.81 50.22 26.63 60.24
8 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97 59.64
9 INT5653 Positive_regulation of ELANE 136 0.70 72.78 27.94 54.80
10 INT8580 Gene_expression of ELANE 132 0.75 62.98 21.79 54.80
11 INT25674 Positive_regulation of Gene_expression of ELANE 16 0.60 7.46 3.12 54.80
12 INT3448 Positive_regulation of Gh 521 0.69 180.03 161.18 40.80
13 INT9682 Positive_regulation of IGF1 238 0.70 120.03 26.36 40.80
14 INT72129 Positive_regulation of Positive_regulation of IGF1 11 0.50 4.61 1.05 40.80
15 INT174100 Gene_expression of YWHAE 14 0.31 12.42 0.08 38.20
16 INT17565 Regulation of Gpt 85 0.60 43.64 13.68 32.12
17 INT22329 Gene_expression of Ptprc 36 0.66 15.84 1.59 20.68
18 INT4597 Regulation of SCD 5 0.39 2.25 0.5 8.88
19 INT73611 Negative_regulation of SCD 15 0.37 26.67 3.71 8.00
20 INT170860 Localization of Samsn1 2 0.23 1.16 0.27 5.24
21 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 5.00
22 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 5.00
23 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98 5.00
24 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 5.00
25 INT6481 Binding of TNF 624 0.48 510.2 214.82 5.00
26 INT11380 Negative_regulation of IL1B 215 0.59 125.62 72.35 5.00
27 INT15913 Negative_regulation of CYP2D6 174 0.59 22.45 70.91 5.00
28 INT17564 Gene_expression of Gpt 322 0.75 208.51 60.36 5.00
29 INT6477 Gene_expression of IL1RN 213 0.77 114.69 58.62 5.00
30 INT73048 Gene_expression of MMP9 268 0.77 159.75 57.81 5.00
31 INT52264 Gene_expression of IK 180 0.77 90.87 51.87 5.00
32 INT6473 Positive_regulation of Gene_expression of IL1B 204 0.70 117.23 50.86 5.00
33 INT29496 Gene_expression of MMP3 136 0.75 49.49 41.78 5.00
34 INT9094 Gene_expression of COL7A1 277 0.77 143.42 38.73 5.00
35 INT8097 Gene_expression of EGF 122 0.77 75.94 28.47 5.00
36 INT129956 Gene_expression of MMP13 145 0.72 60.48 26.98 5.00
37 INT73047 Positive_regulation of MMP9 133 0.68 73.22 26.42 5.00
38 INT11659 Gene_expression of COL2A1 164 0.78 78.49 22.58 5.00
39 INT34488 Negative_regulation of MMP2 85 0.59 41.98 21.72 5.00
40 INT5398 Positive_regulation of ALPP 178 0.70 110.52 19.18 5.00
41 INT712 Positive_regulation of LDHA 160 0.70 175.25 19.11 5.00
42 INT50403 Negative_regulation of CYP2C19 55 0.59 8.97 17.79 5.00
43 INT50404 Negative_regulation of CYP1A2 49 0.59 8.61 17.35 5.00
44 INT10721 Gene_expression of BDNF-AS 119 0.76 72.8 16.29 5.00
45 INT26314 Positive_regulation of MMP3 48 0.67 22.14 16.17 5.00
46 INT102680 Protein_catabolism of COL7A1 49 0.69 34.68 15.78 5.00
47 INT103245 Positive_regulation of Gene_expression of MMP9 64 0.68 36.86 15.7 5.00
48 INT34590 Gene_expression of ALPP 199 0.75 89.85 15.1 5.00
49 INT74587 Gene_expression of MMP8 31 0.78 24.4 14.91 5.00
50 INT18012 Gene_expression of EPO 169 0.78 108.36 13.75 5.00
51 INT123779 Positive_regulation of MMP13 42 0.65 24.3 12.45 5.00
52 INT8548 Gene_expression of HP 86 0.77 47.62 11.94 5.00
53 INT93715 Negative_regulation of MMP9 69 0.55 36.05 11.73 5.00
54 INT13240 Gene_expression of TF 94 0.76 57.81 10.99 5.00
55 INT95632 Positive_regulation of MMP8 26 0.70 10.06 9.96 5.00
56 INT129962 Positive_regulation of Gene_expression of MMP13 41 0.65 20.74 8.54 5.00
57 INT86705 Gene_expression of BTG3 41 0.65 37.29 8.29 5.00
58 INT113987 Localization of IK 29 0.23 16.73 8.25 5.00
59 INT86411 Negative_regulation of Negative_regulation of TNF 24 0.42 17.6 7.89 5.00
60 INT1973 Positive_regulation of NAGLU 36 0.65 14.78 7 5.00
61 INT95117 Gene_expression of PDGFA 71 0.71 51.17 6.9 5.00
62 INT8101 Binding of INCENP 42 0.31 16.2 6.68 5.00
63 INT15872 Positive_regulation of EPO 74 0.70 45.35 6.67 5.00
64 INT22781 Binding of COL7A1 76 0.48 41.59 6.66 5.00
65 INT7205 Positive_regulation of HBG1 65 0.69 40.35 6.37 5.00
66 INT13406 Negative_regulation of CASP1 25 0.57 10.61 6.36 5.00
67 INT79425 Gene_expression of SMN1 42 0.65 36.37 6.1 5.00
68 INT3915 Gene_expression of SCD 25 0.57 13.94 6 5.00
69 INT81049 Positive_regulation of CASP1 44 0.67 19.97 5.69 5.00
70 INT103518 Negative_regulation of SCN2A 17 0.57 8.4 5.4 5.00
71 INT95631 Positive_regulation of Gene_expression of MMP8 16 0.50 13.75 5.12 5.00
72 INT18011 Positive_regulation of HP 60 0.50 31.88 4.75 5.00
73 INT92199 Negative_regulation of Gene_expression of IL1RN 14 0.58 10.11 4.71 5.00
74 INT102237 Positive_regulation of Gene_expression of MMP3 22 0.44 7.77 4.71 5.00
75 INT322999 Binding of SSD 10 0.39 3.86 4.28 5.00
76 INT217742 Positive_regulation of Gene_expression of COL2A1 20 0.67 9.76 4.23 5.00
77 INT23220 Positive_regulation of FOXG1 10 0.43 2.86 3.49 5.00
78 INT98068 Gene_expression of SCN2A 19 0.75 14.42 3.31 5.00
79 INT96542 Negative_regulation of SMN1 14 0.51 10.72 3.11 5.00
80 INT103246 Positive_regulation of Protein_catabolism of COL7A1 8 0.34 8.67 3.03 5.00
81 INT45503 Binding of EPO 42 0.48 24.85 2.88 5.00
82 INT151309 Positive_regulation of Positive_regulation of MMP3 5 0.60 2.62 2.5 5.00
83 INT24672 Localization of FGF2 27 0.71 14.59 2.48 5.00
84 INT101342 Negative_regulation of CYP2A6 11 0.53 3.68 2.39 5.00
85 INT9188 Localization of HBG1 12 0.75 8.14 2.24 5.00
86 INT82768 Binding of MLRG 5 0.23 0.54 2.22 5.00
87 INT35431 Regulation of DFP 3 0.25 1.33 1.97 5.00
88 INT30532 Negative_regulation of DFP 4 0.43 0.9 1.7 5.00
89 INT160533 Gene_expression of NUDT6 24 0.20 18.6 1.7 5.00
90 INT27762 Positive_regulation of Gene_expression of EPO 18 0.70 17.67 1.45 5.00
91 INT287241 Positive_regulation of BMP7 10 0.43 2.68 1.38 5.00
92 INT38990 Negative_regulation of IDUA 12 0.59 5.04 1.33 5.00
93 INT38989 Gene_expression of IDUA 22 0.78 16.99 1.26 5.00
94 INT132453 Binding of TF 31 0.36 12.98 1.22 5.00
95 INT205995 Gene_expression of SLC7A7 11 0.75 10.61 1.21 5.00
96 INT128496 Regulation of CASP1 5 0.38 3.4 1.09 5.00
97 INT96579 Negative_regulation of Negative_regulation of MMP9 5 0.40 4.55 1.04 5.00
98 INT9243 Gene_expression of FOXG1 14 0.53 7.52 1.02 5.00
99 INT147464 Binding of Ptprc 13 0.36 15.18 0.98 5.00
100 INT296385 Binding of IDUA 12 0.39 20.73 0.93 5.00
101 INT84250 Positive_regulation of IDUA 8 0.56 15.89 0.62 5.00
102 INT84826 Negative_regulation of ACD 6 0.50 4.02 0.55 5.00
103 INT128793 Gene_expression of HBB 16 0.78 10.69 0.42 5.00
104 INT186506 Negative_regulation of BTG3 4 0.41 3.31 0.36 5.00
105 INT94543 Binding of MT2A 5 0.29 0.96 0.36 5.00
106 INT122548 Negative_regulation of Localization of FGF2 3 0.41 1.01 0.22 5.00
107 INT94529 Binding of ALG1 2 0.17 0.96 0.21 5.00
108 INT84244 Positive_regulation of Gene_expression of IDUA 5 0.70 3.75 0.19 5.00
109 INT156610 Negative_regulation of HBB 2 0.37 1.25 0.15 5.00
110 INT205991 Negative_regulation of SLC7A7 9 0.41 1.81 0.12 5.00
111 INT41890 Positive_regulation of Gene_expression of FOXG1 2 0.32 1.04 0.09 5.00
112 INT74442 Binding of ATRX 2 0.41 3.2 0.09 5.00
113 INT296382 Positive_regulation of SLC11A2 3 0.31 1.49 0.08 5.00
114 INT279349 Localization of IDUA 7 0.76 4.97 0.07 5.00
115 INT128794 Negative_regulation of Gene_expression of HBB 1 0.59 5.98 0.06 5.00
116 INT232406 Positive_regulation of DFP 1 0.28 1.29 0.06 5.00
117 INT162956 Binding of ACD 3 0.32 3.04 0.05 5.00
118 INT296384 Regulation of SLC40A1 2 0.01 0.83 0.03 5.00
119 INT296386 Localization of DEFA6 3 0.05 0.88 0 5.00
120 INT186639 Gene_expression of SLC11A2 4 0.65 1.91 0 5.00
121 INT207239 Binding of HBE1 2 0.20 1.53 0 5.00
122 INT318137 Negative_regulation of PMCH 1 0.02 0.96 0 5.00
123 INT296383 Regulation of SLC11A2 1 0.07 0.33 0 5.00
124 INT350734 Positive_regulation of MGAT5B 1 0.01 0.32 0 5.00
125 INT296387 Localization of SLC40A1 2 0.44 0.94 0 5.00
126 INT318136 Positive_regulation of Gene_expression of HBB 1 0.04 2.65 0 5.00
127 INT350724 Negative_regulation of Cm2 1 0.04 0.3 0 5.00
128 INT232407 Negative_regulation of Gene_expression of DFP 1 0.24 0.53 0 5.00
129 INT186505 Negative_regulation of Gene_expression of BTG3 1 0.03 1.46 0 5.00
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