D:Sinusitis

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Disease Term
Synonyms Acute Sinusitis, Chronic Sinusitis, Sinus Infection, Sinus Infections, Sinusitides
Documents 1048
Hot Single Events 110
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Sinusitis. They are ordered first by their relevance to Sinusitis and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT336713 Binding of CDA and GNPTAB 1 0.02 0.77 0 69.20
2 INT194383 Il13 Positive_regulation of Gene_expression of Il4 1 0.00 1.75 0.13 61.16
3 INT336835 Binding of CACNG6 and Aia1 1 0.01 3.41 0.75 54.00
4 INT194385 Il13 Positive_regulation of Gene_expression of IGHE 1 0.00 0.8 0.09 50.00
5 INT321601 Binding of C3 and PRTN3 1 0.00 0.99 0.27 48.60
6 INT321602 Binding of C4A and PRTN3 1 0.00 0.99 0.27 48.60
7 INT199436 Binding of Capns1 and Cysltr1 1 0.00 0.79 0.1 34.24
8 INT196639 Negative_regulation of NA Negative_regulation of Transcription of CFTR 1 0.02 0.63 0.03 33.20
9 INT300192 Gene_expression of APOA1 Positive_regulation of HSD11B1 1 0.16 1.08 0.08 24.48
10 INT300193 Binding of APOA1 and INSL4 1 0.01 2.17 0.18 19.28
11 INT101942 Binding of CD40 and CD40LG 16 0.23 15.24 4.01 5.00
12 INT271408 NGF Positive_regulation of Gene_expression of CALCA 1 0.09 4.89 1.88 5.00
13 INT66504 Binding of Agt and Agtr1a 8 0.39 3.78 1.78 5.00
14 INT194863 Binding of IL1R1 and IL1RN 5 0.09 2.23 1.64 5.00
15 INT229094 Binding of IL1RN and Il1r1 1 0.01 1.9 1.5 5.00
16 INT54972 Binding of EDNRA and EDNRB 7 0.52 3.31 0.97 5.00
17 INT271409 NGF Positive_regulation of TRPV1 1 0.08 2.45 0.94 5.00
18 INT271410 NGF Positive_regulation of Gene_expression of TRPV1 1 0.07 2.45 0.94 5.00
19 INT232417 Binding of Mtx1 and Ifx 1 0.04 0.99 0.86 5.00
20 INT196638 TNF Positive_regulation of F2RL1 2 0.09 1.52 0.84 5.00
21 INT196632 IL1B Positive_regulation of F2RL1 2 0.05 1.52 0.84 5.00
22 INT226371 IL18 Positive_regulation of IL4 4 0.05 2.49 0.79 5.00
23 INT229085 IL1RN Negative_regulation of Positive_regulation of IL1R1 1 0.12 1.72 0.68 5.00
24 INT278827 Binding of EDN1 and EDNRB 3 0.17 2.7 0.67 5.00
25 INT211105 Binding of CRS and IGHE 1 0.02 3.63 0.66 5.00
26 INT193218 Binding of PTGER1 and PTGER2 3 0.12 2.31 0.66 5.00
27 INT351276 CYP2D6 Regulation of CYP1A2 1 0.12 0 0.63 5.00
28 INT178097 Binding of EDN1 and EDNRA 7 0.21 5.97 0.62 5.00
29 INT334500 Binding of IGHE and SPARCL1 1 0.01 1.47 0.55 5.00
30 INT164902 Binding of IL1RL1 and IL33 4 0.37 1.2 0.53 5.00
31 INT356351 Binding of CALM1 and TNC 1 0.02 0 0.52 5.00
32 INT106744 Binding of CRP and EGFL7 2 0.07 2.35 0.51 5.00
33 INT229095 Binding of IL1R1 and Il1r1 1 0.00 0.64 0.5 5.00
34 INT278825 Positive_regulation of Binding of EDN1 and EDNRB 3 0.16 1.24 0.49 5.00
35 INT300551 TBX21 Regulation of Hand1 2 0.10 0.44 0.48 5.00
36 INT196634 IFNG Negative_regulation of DNAH8 1 0.03 1.49 0.47 5.00
37 INT331731 Binding of C3 and CD79A 1 0.02 0.85 0.46 5.00
38 INT193219 Binding of LTC4S and CYSLTR2 2 0.28 2.2 0.44 5.00
39 INT193217 Binding of PTGER2 and PTGER3 2 0.10 1.31 0.43 5.00
40 INT299181 Cysltr1 Regulation of Musk 1 0.08 1.21 0.4 5.00
41 INT196644 PTGER2 Positive_regulation of Gene_expression of NA 1 0.00 0.93 0.35 5.00
42 INT300751 Binding of IGHE and Hand2 1 0.04 0 0.34 5.00
43 INT300727 IL25 Positive_regulation of IL33 Positive_regulation of IL13 1 0.00 0 0.34 5.00
44 INT4638 Binding of Agt and Adarb1 3 0.01 0 0.34 5.00
45 INT300732 IL33 Positive_regulation of IL13 1 0.00 0 0.34 5.00
46 INT229087 IL1R1 Negative_regulation of ACCS 1 0.03 0.86 0.33 5.00
47 INT300728 IL33 Positive_regulation of IL4 1 0.00 0 0.33 5.00
48 INT300729 IL18 Positive_regulation of IL13 1 0.00 0 0.33 5.00
49 INT196618 Binding of KNG1 and Positive_regulation of NA 1 0.01 0.19 0.32 5.00
50 INT196623 Binding of KNG1 and Positive_regulation of DNAH8 1 0.01 0.19 0.32 5.00
51 INT229363 Negative_regulation of Binding of Agt and Agtr1a 2 0.22 0.9 0.32 5.00
52 INT300742 Stat6 Regulation of Hand2 1 0.01 0.06 0.3 5.00
53 INT284137 EDNRB Regulation of EDNRA 1 0.07 0.09 0.3 5.00
54 INT300752 GATA3 Regulation of Hand2 1 0.01 0.06 0.3 5.00
55 INT196605 Binding of DNAH8 and SPANXB1 Positive_regulation of DNAH8 1 0.00 0.08 0.3 5.00
56 INT196604 Binding of DNAH8 and SPANXB1 Positive_regulation of NA 1 0.00 0.08 0.3 5.00
57 INT334499 Binding of AMELX and IL4 1 0.12 0.47 0.29 5.00
58 INT196641 Binding of KNG1 and Negative_regulation of DNAH8 1 0.01 0.19 0.29 5.00
59 INT196612 Binding of KNG1 and Negative_regulation of NA 1 0.01 0.19 0.29 5.00
60 INT196621 PTGER2 Negative_regulation of Gene_expression of DNAH8 1 0.00 0.33 0.28 5.00
61 INT196631 PTGER2 Negative_regulation of NFKB1 1 0.00 0.32 0.28 5.00
62 INT196626 Binding of DNAH8 and KNG1 1 0.00 0.08 0.27 5.00
63 INT196695 Prkaca Positive_regulation of CFTR 1 0.46 0.13 0.27 5.00
64 INT196637 Binding of DNAH8 and SPANXB1 1 0.00 0.08 0.27 5.00
65 INT196613 Binding of KNG1 and NA 1 0.01 0.08 0.27 5.00
66 INT196616 Binding of NA and SPANXB1 1 0.00 0.08 0.27 5.00
67 INT264569 Binding of STS and ATF7IP 1 0.03 0.15 0.25 5.00
68 INT319229 Binding of SNRNP70 and Aia1 2 0.00 2.92 0.25 5.00
69 INT319383 Binding of CCL18 and CCL22 1 0.19 1.07 0.25 5.00
70 INT196614 TNF Positive_regulation of Positive_regulation of NA 1 0.03 0.88 0.24 5.00
71 INT196615 TNF Positive_regulation of Negative_regulation of DNAH8 1 0.02 0.88 0.24 5.00
72 INT196609 IFNG Positive_regulation of Positive_regulation of NA 1 0.03 0.87 0.24 5.00
73 INT196622 IFNG Positive_regulation of Positive_regulation of DNAH8 1 0.03 0.87 0.24 5.00
74 INT196647 IFNG Negative_regulation of NA 1 0.04 0.79 0.24 5.00
75 INT196620 TNF Positive_regulation of Positive_regulation of DNAH8 1 0.03 0.88 0.24 5.00
76 INT196646 IFNG Positive_regulation of Negative_regulation of DNAH8 1 0.03 0.87 0.24 5.00
77 INT255044 GLP1R Positive_regulation of Localization of INS 3 0.49 1.47 0.22 5.00
78 INT284139 EDNRB Positive_regulation of Gene_expression of EDNRA 1 0.12 0.45 0.22 5.00
79 INT196629 PTGER2 Negative_regulation of Gene_expression of NA 1 0.00 0.24 0.22 5.00
80 INT311872 IGHE Positive_regulation of Localization of Mmp9 1 0.01 1.35 0.22 5.00
81 INT196635 CFTR Positive_regulation of Gene_expression of CCL5 1 0.07 0.44 0.21 5.00
82 INT193215 Binding of CYSLTR1 and CYSLTR2 2 0.09 1.7 0.21 5.00
83 INT284142 ERAS Regulation of PAH 1 0.10 0.55 0.2 5.00
84 INT284138 ERAS Regulation of Positive_regulation of PAH 1 0.10 0.55 0.2 5.00
85 INT196610 IFNG Negative_regulation of CFTR 1 0.17 0.21 0.19 5.00
86 INT193214 Binding of PTGER2 and PTGER4 2 0.08 2.51 0.18 5.00
87 INT287145 Binding of PNN and Shbg 1 0.07 0.14 0.18 5.00
88 INT280052 Negative_regulation of Dpp4 Positive_regulation of Zglp1 1 0.03 0.72 0.18 5.00
89 INT267660 CFTR Regulation of Gene_expression of P2RX2 1 0.25 0.51 0.18 5.00
90 INT319381 Binding of ST2 and IL33 1 0.13 1.01 0.18 5.00
91 INT300753 Binding of Cd28 and Positive_regulation of Transcription of IL13 1 0.00 0 0.17 5.00
92 INT196606 IFNG Positive_regulation of CFTR 1 0.16 0.45 0.16 5.00
93 INT193216 Binding of LTC4S and CYSLTR1 1 0.04 0.71 0.16 5.00
94 INT298717 Fgf2 Positive_regulation of Gene_expression of PDGFA 1 0.01 0.23 0.15 5.00
95 INT298716 Ngf Positive_regulation of Gene_expression of PDGFA 1 0.01 0.22 0.15 5.00
96 INT196608 TNF Negative_regulation of CFTR 1 0.16 0.11 0.14 5.00
97 INT229088 IL1R1 Positive_regulation of Gene_expression of IL6 1 0.04 0.45 0.14 5.00
98 INT298715 Igf1 Positive_regulation of Gene_expression of PDGFA 1 0.00 0.22 0.14 5.00
99 INT300731 IL10 Negative_regulation of Gene_expression of IGHE 1 0.03 0.23 0.13 5.00
100 INT196648 PTGER2 Regulation of DNAH8 1 0.00 0.14 0.12 5.00
101 INT270723 Negative_regulation of HMGCR Positive_regulation of LDLR 1 0.02 0.52 0.12 5.00
102 INT181740 Il1 Positive_regulation of Csf2 1 0.02 0 0.12 5.00
103 INT196636 PTGER2 Regulation of NA 1 0.00 0.14 0.12 5.00
104 INT229089 IL1R1 Positive_regulation of IL6 1 0.03 0.45 0.12 5.00
105 INT311871 Cav1 Regulation of Mch 1 0.01 0.24 0.11 5.00
106 INT284552 Binding of Cd8a and Mthfd1 2 0.03 1.32 0.1 5.00
107 INT284140 Binding of EDNRB and PAH 1 0.08 0.1 0.1 5.00
108 INT280053 Negative_regulation of Dpp4 Negative_regulation of Protein_catabolism of Zglp1 1 0.02 0.71 0.1 5.00
109 INT196627 IL1B Regulation of DNAH8 1 0.00 0.63 0.09 5.00
110 INT196643 IL1B Regulation of NA 1 0.00 0.63 0.09 5.00
111 INT196619 KNG1 Regulation of DNAH8 1 0.00 0.62 0.09 5.00
112 INT284141 Binding of EDNRA and PAH 1 0.05 0.1 0.09 5.00
113 INT196645 KNG1 Regulation of NA 1 0.00 0.62 0.09 5.00
114 INT196642 IL1B Positive_regulation of Gene_expression of DNAH8 1 0.00 0 0.08 5.00
115 INT196640 PTGER2 Negative_regulation of DNAH8 1 0.00 0.46 0.08 5.00
116 INT196611 PTGER2 Negative_regulation of NA 1 0.00 0.46 0.08 5.00
117 INT196630 TNF Regulation of Gene_expression of NA 1 0.04 0.16 0.08 5.00
118 INT196624 TNF Negative_regulation of Transcription of SCNN1G 1 0.02 0.07 0.07 5.00
119 INT264568 Binding of STS and CYP1A2 1 0.20 0.18 0.06 5.00
120 INT310674 Positive_regulation of Binding of ARSB and ELF3 1 0.07 2.46 0.05 5.00
121 INT229711 Positive_regulation of Nr4a3 Regulation of Ins1 1 0.01 0.29 0.05 5.00
122 INT280057 Zglp1 Positive_regulation of Transcription of INS 1 0.04 0.52 0.05 5.00
123 INT196628 IFNG Negative_regulation of Gene_expression of DNAH8 1 0.02 0.31 0.05 5.00
124 INT229712 Nr4a3 Regulation of Ins1 1 0.01 0.29 0.05 5.00
125 INT310675 Binding of ARSB and ELF3 1 0.06 2.4 0.05 5.00
126 INT319384 Binding of AR and SCGB2A2 1 0.01 1.36 0.04 5.00
127 INT334497 Positive_regulation of IGHG3 Positive_regulation of IGHE 1 0.01 0.81 0.04 5.00
128 INT334496 IGHG3 Positive_regulation of IGHE 1 0.01 0.75 0.04 5.00
129 INT319382 Binding of IL13 and CRISP3 1 0.09 0.87 0.03 5.00
130 INT247439 Binding of APOA1 and HSD11B1 3 0.32 5.01 0.03 5.00
131 INT196617 TNF Negative_regulation of Gene_expression of SCNN1G 1 0.02 0.08 0.03 5.00
132 INT307704 Binding of Gsr and Rb(8.17)6Sic 1 0.01 1.49 0.03 5.00
133 INT196625 TNF Negative_regulation of Positive_regulation of SCNN1G 1 0.02 0.14 0.03 5.00
134 INT311870 Positive_regulation of Binding of Cd8a and Mthfd1 1 0.00 0.32 0.03 5.00
135 INT196607 IFNG Regulation of Gene_expression of SCNN1G 1 0.03 0.08 0.03 5.00
136 INT300191 Binding of C1S and HSD11B1 1 0.13 1.75 0 5.00
137 INT300195 Binding of C1S and CHDH 1 0.23 2.51 0 5.00
138 INT334498 Binding of IL13 and KLF1 1 0.00 0.63 0 5.00
139 INT284143 EDN1 Positive_regulation of CA2 1 0.03 0.37 0 5.00
140 INT229713 Binding of Agt and Ren 1 0.14 0 0 5.00
141 INT229714 Positive_regulation of Binding of Agt and Ren 1 0.18 0 0 5.00
142 INT227399 Binding of D5Mit424 and Alms1 1 0.01 0.71 0 5.00
143 INT300194 HSD11B1 Negative_regulation of CHDH 1 0.08 2.19 0 5.00
144 INT311816 CD79A Positive_regulation of RAB27A 1 0.01 0.47 0 5.00
145 INT255041 DPP4 Positive_regulation of GIP 1 0.49 0.32 0 5.00
146 INT300199 PCSK9 Regulation of Gene_expression of LDLR 1 0.13 0.88 0 5.00
147 INT336836 Binding of RS1 and Aia1 1 0.00 0.33 0 5.00
148 INT255043 DPP4 Positive_regulation of GLP1R 1 0.35 0.32 0 5.00
149 INT300197 Binding of APOA1 and C1S 1 0.39 3.56 0 5.00
150 INT300196 Binding of HSD11B1 and CHDH 1 0.07 4.01 0 5.00
151 INT227398 Binding of H2afy and Alms1 1 0.01 1.42 0 5.00
152 INT300198 Positive_regulation of Binding of C1S and CHDH 1 0.31 1.63 0 5.00
153 INT255042 Negative_regulation of DPP4 Positive_regulation of GLP1R 1 0.33 0.34 0 5.00
154 INT336829 RS1 Regulation of CACNG6 1 0.15 0.15 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Sinusitis. They are ordered first by their pain relevance and then by number of times they were reported in Sinusitis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT73253 Binding of Efs 3 0.36 2.4 0.33 100.00
2 INT188844 Gene_expression of AES 44 0.58 33.94 5.85 100.00
3 INT31341 Positive_regulation of CSE 15 0.60 11.57 12.29 99.84
4 INT671 Positive_regulation of Cea 221 0.69 164.5 47.79 99.84
5 INT272057 Phosphorylation of COPD 2 0.54 4.15 0.22 99.66
6 INT154309 Gene_expression of gp 18 0.66 6.79 1.58 99.50
7 INT20712 Regulation of gp 8 0.36 1.06 1.67 99.24
8 INT42039 Positive_regulation of Spink1 11 0.67 8.4 2.48 98.92
9 INT101891 Negative_regulation of Cftr 25 0.58 24.09 9.55 98.88
10 INT3375 Gene_expression of IGHE 535 0.77 387.47 65.46 98.60
11 INT18833 Positive_regulation of LTB4R 19 0.69 27.61 10.17 98.40
12 INT103842 Gene_expression of Cftr 53 0.78 59.59 21.82 98.32
13 INT117223 Gene_expression of TLR4 348 0.78 206.18 54.42 98.32
14 INT215301 Binding of PQBP1 9 0.27 10.36 0.59 98.32
15 INT186808 Transcription of TLR4 22 0.69 12.77 3.73 98.32
16 INT74464 Binding of GNPTAB 9 0.17 3.32 1.17 98.28
17 INT133028 Gene_expression of TLR2 209 0.73 131.92 36.17 97.96
18 INT186805 Transcription of TLR2 12 0.63 9.66 3.04 97.96
19 INT33358 Gene_expression of Cysltr1 46 0.62 24.18 13.36 97.80
20 INT65286 Binding of ARIH1 10 0.48 4.3 0.76 97.60
21 INT84307 Binding of Cftr 31 0.47 26.19 12.8 97.56
22 INT3987 Positive_regulation of IGHE 316 0.70 283.2 40.16 97.52
23 INT3988 Positive_regulation of Gene_expression of IGHE 98 0.68 91.46 9.61 97.52
24 INT35366 Binding of AR 87 0.47 30.52 8.9 97.40
25 INT37907 Positive_regulation of Capns1 9 0.41 3.55 4.1 97.10
26 INT192650 Positive_regulation of Gene_expression of Capns1 1 0.35 1.09 0 97.10
27 INT192651 Positive_regulation of Positive_regulation of Capns1 1 0.35 0.54 0 97.10
28 INT145768 Regulation of TLR4 19 0.45 8.31 2.96 96.80
29 INT14165 Negative_regulation of Ahr 14 0.51 8.35 4.17 96.72
30 INT168373 Gene_expression of Capns1 4 0.58 4.55 1.34 96.70
31 INT15888 Positive_regulation of Nbr1 42 0.69 35.76 10.48 96.68
32 INT62041 Negative_regulation of Gene_expression of IGHE 37 0.58 37.86 5.27 96.64
33 INT35164 Negative_regulation of IGHE 96 0.58 76.3 9.74 96.64
34 INT196682 Negative_regulation of Gene_expression of CFTR 6 0.34 1.96 0.73 96.12
35 INT138802 Gene_expression of CFTR 36 0.70 18.8 7.02 95.60
36 INT96693 Binding of COL2A1 45 0.46 37.11 2.61 95.32
37 INT84308 Localization of Cftr 12 0.75 6.16 1.65 94.76
38 INT78896 Negative_regulation of Localization of CCL5 8 0.57 2.43 1.59 94.44
39 INT61316 Gene_expression of Coq10a 59 0.73 32.81 3.95 94.40
40 INT78901 Localization of CCL5 67 0.78 40.79 20.59 94.08
41 INT334504 Regulation of Transcription of IGHE 1 0.29 7.97 0.57 94.04
42 INT14166 Positive_regulation of Ahr 32 0.61 20.78 7.47 94.04
43 INT79060 Gene_expression of NOS2 116 0.78 69.25 34.84 93.84
44 INT35866 Transcription of IGHE 9 0.60 12.83 2.19 93.68
45 INT310677 Localization of ARSB 1 0.71 5.72 0.14 93.68
46 INT11659 Gene_expression of COL2A1 164 0.78 78.49 22.58 93.24
47 INT915 Positive_regulation of PRL 342 0.70 141.96 104.31 93.20
48 INT615 Regulation of Alb 66 0.62 33.43 15.33 92.96
49 INT117232 Localization of COL2A1 11 0.72 7.34 1.3 92.76
50 INT76336 Negative_regulation of PDE5A 192 0.59 112.02 20.09 92.60
51 INT6580 Negative_regulation of Ptgs1 929 0.59 381.53 376.26 92.24
52 INT117220 Positive_regulation of TLR4 64 0.69 53.61 17.33 92.08
53 INT336718 Positive_regulation of Localization of ARIH1 1 0.22 0.94 0.09 91.96
54 INT201955 Regulation of DPP4 18 0.45 11.91 1.18 91.80
55 INT281839 Localization of ARIH1 2 0.54 3.03 0.09 91.64
56 INT137206 Positive_regulation of TLR2 47 0.65 33.36 6.4 91.52
57 INT132036 Negative_regulation of DPP4 126 0.59 63.24 9.51 91.36
58 INT50058 Negative_regulation of Cpox 907 0.58 426.28 428.29 91.20
59 INT36554 Gene_expression of PRSS1 70 0.78 50.25 15.33 90.76
60 INT24439 Gene_expression of Spink1 19 0.63 10.05 4.35 90.76
61 INT48955 Gene_expression of Nos2 753 0.78 403.87 208.08 90.64
62 INT52531 Gene_expression of Nfkb1 153 0.75 82.84 42.9 90.64
63 INT50674 Gene_expression of PTGS2 459 0.78 253.33 118.51 90.64
64 INT19330 Binding of HLA-A 99 0.48 76.26 22.85 90.44
65 INT147792 Gene_expression of COPD 230 0.70 287.13 24.1 90.20
66 INT135133 Binding of NR1I2 7 0.42 1.7 0.29 90.08
67 INT48953 Positive_regulation of Nos2 486 0.70 239.85 131.87 90.08
68 INT33466 Negative_regulation of C4B 14 0.43 9.06 4.64 90.08
69 INT57549 Gene_expression of GNPTAB 49 0.65 57.5 9.05 90.04
70 INT320680 Regulation of Gene_expression of GNPTAB 2 0.32 2.14 0.09 90.04
71 INT101166 Negative_regulation of Binding of Cpox 4 0.15 2.66 1.79 88.32
72 INT9130 Negative_regulation of TGFB1 16 0.41 12.21 2.92 88.20
73 INT55335 Binding of Cpox 49 0.34 15.48 18.46 88.00
74 INT137178 Gene_expression of TLR3 46 0.72 24.97 4.33 87.68
75 INT182320 Binding of MTX1 14 0.18 8.5 7.65 87.68
76 INT98226 Negative_regulation of Cd79a 5 0.49 3.99 2.66 87.68
77 INT186803 Transcription of TLR3 6 0.67 1.54 0.2 87.68
78 INT1497 Negative_regulation of Gh 415 0.59 192.95 74.71 87.60
79 INT267667 Regulation of Clcn1 1 0.44 1.05 0.23 86.96
80 INT32580 Gene_expression of C4B 24 0.75 17.95 7.75 86.88
81 INT53475 Gene_expression of MRI1 116 0.59 77.68 33.98 86.76
82 INT10605 Positive_regulation of Ltc4s 21 0.68 17.22 4.8 86.40
83 INT10248 Gene_expression of KRT20 436 0.78 231.96 32.88 86.40
84 INT69876 Negative_regulation of Nfkb1 147 0.58 89.81 55.5 86.36
85 INT111533 Positive_regulation of Gene_expression of Nfkb1 27 0.52 17.32 7.89 86.36
86 INT88873 Negative_regulation of Gene_expression of Nfkb1 24 0.56 9.93 5.97 86.36
87 INT257838 Negative_regulation of Binding of BTK 1 0.07 2.02 0 85.88
88 INT47662 Localization of CHKB 34 0.81 22.63 5.14 85.68
89 INT130015 Positive_regulation of Localization of CHKB 3 0.48 1.72 0.39 85.68
90 INT151101 Regulation of CFTR 4 0.62 3.69 1.89 85.60
91 INT257839 Binding of BTK 1 0.06 2.84 0 85.48
92 INT147793 Localization of COPD 70 0.64 89.01 7.3 85.28
93 INT180497 Binding of MRI1 45 0.42 28.35 14.77 85.16
94 INT168374 Negative_regulation of Capns1 2 0.50 5.09 1.1 83.52
95 INT79061 Positive_regulation of NOS2 92 0.65 58.89 23.96 83.20
96 INT63839 Binding of CRS 31 0.41 34.05 4.7 83.04
97 INT48593 Positive_regulation of NOS1 420 0.68 226.15 114.71 82.72
98 INT182720 Binding of SHE 18 0.26 9.15 2.24 82.60
99 INT48767 Negative_regulation of NOS1 312 0.59 154.25 90.32 82.40
100 INT86717 Negative_regulation of Positive_regulation of NOS1 18 0.30 8.88 5.2 82.40
101 INT49017 Negative_regulation of Gene_expression of Nos2 169 0.59 80.64 52.67 81.96
102 INT95369 Positive_regulation of Gene_expression of NOS2 36 0.55 25.09 11.37 81.44
103 INT80688 Positive_regulation of Positive_regulation of MAPK1 72 0.69 39.35 14.11 81.44
104 INT6477 Gene_expression of IL1RN 213 0.77 114.69 58.62 81.40
105 INT105991 Negative_regulation of IDS 12 0.38 6.31 1.04 81.40
106 INT27387 Binding of Aecp 4 0.34 5.09 1 81.20
107 INT72565 Localization of IL1RN 45 0.80 23.59 13.17 80.84
108 INT46383 Negative_regulation of TRGC1 42 0.55 44.03 6.2 80.80
109 INT34869 Negative_regulation of PTGS2 778 0.59 366.76 319.85 80.24
110 INT51685 Gene_expression of LTB4R 87 0.58 68.69 31.72 80.08
111 INT3104 Negative_regulation of CGA 76 0.54 29.81 12.23 79.84
112 INT194377 Positive_regulation of Localization of CRS 2 0.29 1.61 0.06 79.44
113 INT71789 Positive_regulation of MAPK1 396 0.70 234.44 89.27 79.32
114 INT236711 Gene_expression of Bcl6 15 0.30 12.98 0.58 79.28
115 INT34354 Gene_expression of SRMS 8 0.59 9.62 1.02 79.16
116 INT70970 Binding of COPD 144 0.42 180.34 18.29 79.00
117 INT11380 Negative_regulation of IL1B 215 0.59 125.62 72.35 78.36
118 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97 78.36
119 INT116498 Negative_regulation of Negative_regulation of IL1B 7 0.41 3.08 1.7 78.36
120 INT194379 Localization of CRS 7 0.64 8.58 0.57 78.20
121 INT170757 Positive_regulation of Gene_expression of Cftr 3 0.51 11.41 4.75 78.12
122 INT7997 Gene_expression of Ltc4s 51 0.76 34.28 13.8 77.92
123 INT20743 Positive_regulation of Gene_expression of Ltc4s 13 0.60 12.3 3.86 77.92
124 INT9852 Positive_regulation of Gpt 563 0.70 364.64 146.82 77.52
125 INT5206 Gene_expression of AR 316 0.78 113.83 27.29 77.48
126 INT187294 Positive_regulation of H2BFM 1 0.02 0.76 0.16 77.40
127 INT113517 Binding of Fas 16 0.37 15.86 4.62 77.08
128 INT105816 Gene_expression of P2RY2 53 0.78 16.47 9.67 76.76
129 INT310679 Positive_regulation of ARSB 1 0.39 2.36 0.04 76.72
130 INT89130 Positive_regulation of Transcription of NOS2 7 0.50 3.32 2.14 76.60
131 INT116728 Negative_regulation of ARSH 9 0.13 9.67 0.27 76.52
132 INT36855 Gene_expression of P2RY6 19 0.42 6.16 4.45 76.52
133 INT113996 Gene_expression of RS1 23 0.72 7.7 3.16 76.20
134 INT22875 Regulation of CRS 16 0.39 14.33 2.69 76.16
135 INT211107 Regulation of Regulation of CRS 1 0.32 0.99 0.21 76.16
136 INT89133 Transcription of NOS2 13 0.71 6.84 2.93 76.08
137 INT310681 Negative_regulation of ARSB 1 0.56 6.95 0.29 76.00
138 INT69160 Positive_regulation of IL5 41 0.65 36.04 7.75 75.68
139 INT310683 Protein_catabolism of ARSB 1 0.73 1.85 0.04 75.68
140 INT77282 Positive_regulation of Cftr 23 0.69 21.8 9.65 75.36
141 INT9233 Negative_regulation of Gene_expression of IL1B 114 0.59 56.99 41.82 75.00
142 INT13186 Positive_regulation of Il4 113 0.68 71.22 31.4 75.00
143 INT7093 Negative_regulation of CYP2B6 146 0.58 37.3 48.39 74.44
144 INT122812 Gene_expression of SNRNP70 130 0.75 67 12.5 74.32
145 INT310678 Protein_catabolism of ARSH 1 0.06 1.76 0.04 74.04
146 INT87212 Negative_regulation of Positive_regulation of Nfkb1 74 0.57 38.21 28.31 73.96
147 INT93481 Negative_regulation of Protein_catabolism of Nfkbia 14 0.39 7.24 7.21 73.96
148 INT101937 Negative_regulation of Protein_catabolism of Nfkb1 6 0.19 3.21 2.21 73.96
149 INT71877 Positive_regulation of Protein_catabolism of Nfkb1 9 0.24 2.73 3.06 73.36
150 INT145594 Gene_expression of Mtx1 64 0.57 35.33 30.35 73.04
151 INT69157 Gene_expression of IL5 127 0.77 102.58 26.81 72.96
152 INT62124 Gene_expression of NOS1 444 0.78 218.08 114.85 72.72
153 INT20374 Gene_expression of Il4 515 0.76 306.15 114.12 72.48
154 INT94432 Negative_regulation of Transcription of NOS2 4 0.39 0.67 0.31 72.08
155 INT163274 Gene_expression of H2BFM 3 0.36 1.08 0.36 71.92
156 INT63816 Binding of Aia1 20 0.23 22.28 4.13 71.76
157 INT54571 Positive_regulation of NFKB1 263 0.70 138.99 87.32 70.00
158 INT9994 Negative_regulation of Localization of C6orf25 3 0.09 1.54 0.13 69.68
159 INT88498 Protein_catabolism of Nfkbia 14 0.82 6.94 7.1 69.64
160 INT8640 Positive_regulation of HSD11B1 332 0.67 377.84 22.36 69.56
161 INT608 Negative_regulation of KNG1 98 0.43 72.36 31.23 69.32
162 INT60436 Negative_regulation of COPD 76 0.37 84.22 9.08 69.32
163 INT259580 Negative_regulation of Binding of COPD 2 0.10 3.44 0.17 69.32
164 INT127062 Positive_regulation of Gene_expression of LTB4R 18 0.34 15.9 5.64 69.28
165 INT228707 Positive_regulation of Gene_expression of MPO 10 0.57 17.85 2.1 69.28
166 INT71878 Protein_catabolism of Nfkb1 24 0.65 10.85 9.46 69.08
167 INT88559 Negative_regulation of Spink1 25 0.56 21.81 9.28 68.96
168 INT108282 Negative_regulation of Binding of Spink1 1 0.34 1.3 0.62 68.96
169 INT103378 Binding of Spink1 24 0.40 15.3 6.19 68.96
170 INT9995 Localization of C6orf25 13 0.69 6.48 2.29 68.72
171 INT227515 Regulation of Gene_expression of Mtx1 5 0.38 4.34 3.24 68.64
172 INT27096 Positive_regulation of Nfkb1 325 0.70 195.11 109.06 68.40
173 INT117222 Positive_regulation of Gene_expression of TLR4 80 0.70 51.6 12.9 68.32
174 INT50405 Negative_regulation of CYP3A4 238 0.59 53.65 51.51 67.96
175 INT186807 Positive_regulation of Gene_expression of TLR3 8 0.53 7.19 1.08 67.60
176 INT55114 Gene_expression of CRS 42 0.58 26.86 4.69 67.36
177 INT55113 Positive_regulation of Gene_expression of CRS 5 0.29 4.92 1.25 67.36
178 INT108281 Negative_regulation of Binding of Cftr 4 0.43 3.1 1.38 67.20
179 INT55093 Negative_regulation of SPINK1 13 0.42 15.11 3.8 67.20
180 INT108283 Negative_regulation of Binding of PRSS1 2 0.28 0.82 0.31 67.20
181 INT108284 Negative_regulation of Binding of SPINK1 1 0.10 0.65 0.31 67.20
182 INT133030 Positive_regulation of Gene_expression of TLR2 53 0.65 38.15 10.65 67.12
183 INT76415 Regulation of Il5 6 0.18 3.56 1.4 67.04
184 INT22024 Negative_regulation of HBG1 45 0.58 26 6.8 67.00
185 INT34585 Negative_regulation of Positive_regulation of HSD11B1 31 0.57 43.54 2.47 66.80
186 INT16772 Gene_expression of MPO 81 0.78 90.98 11.9 66.60
187 INT106359 Regulation of Plau 7 0.45 3.51 1.5 66.40
188 INT574 Negative_regulation of C1S 9 0.47 11.25 1.41 66.20
189 INT49759 Negative_regulation of CETP 43 0.58 52 2.68 66.00
190 INT70503 Regulation of Gene_expression of Nos2 71 0.62 44 24.01 65.48
191 INT71786 Phosphorylation of MAPK1 256 0.82 110.09 46.17 65.28
192 INT50580 Binding of PPIG 39 0.36 11.17 12.34 65.24
193 INT17442 Gene_expression of ALOX5 110 0.75 51.55 18.29 64.96
194 INT44254 Regulation of Gene_expression of ALOX5 12 0.43 7.06 3.65 64.96
195 INT23654 Binding of SPINK1 27 0.48 30.85 11.53 64.32
196 INT6481 Binding of TNF 624 0.48 510.2 214.82 64.00
197 INT52113 Gene_expression of CETP 25 0.69 25.71 0.99 63.72
198 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74 63.60
199 INT50387 Negative_regulation of AR 67 0.45 26.31 6.61 63.32
200 INT10836 Negative_regulation of IL8 95 0.59 52.59 24.71 61.92
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