D:Skin Cancer

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Disease Term
Synonyms Acel Lentiginous Melanoma, Basal Cell Carcinoma, Bowen S Disease, BOWENOID PAPULOSIS, CANCER OF SKIN, Cancer Of The Skin, Cancer Skin, Cancers Skin, Cutaneous Melanoma, CYLINDROMATOSIS, Dermal Cancer
Documents 3648
Hot Single Events 200
Hot Interactions 200

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Skin Cancer. They are ordered first by their relevance to Skin Cancer and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT355542 Binding of XRCC3 and BCC1 1 0.00 1.19 0.07 100.00
2 INT151136 MC1R Regulation of Mchr1 1 0.00 0.43 0.1 100.00
3 INT140234 Gene_expression of GRK6 Positive_regulation of Gene_expression of MC1R 1 0.52 0.31 0.68 100.00
4 INT140237 Gene_expression of ADRBK1 Positive_regulation of Gene_expression of MC1R 1 0.46 0.31 0.68 100.00
5 INT148352 Binding of MC1R and XRCC3 1 0.36 0.34 0.62 100.00
6 INT133047 TNF Positive_regulation of Gene_expression of CEL 1 0.47 0.61 0.05 100.00
7 INT99170 Binding of Mc1r and Tyr 1 0.11 0.2 0.64 100.00
8 INT217142 MIR98 Regulation of Gene_expression of HMGA2 1 0.40 2.22 0 100.00
9 INT152891 Ptger2 Positive_regulation of Positive_regulation of JUN 1 0.00 0.23 0.07 100.00
10 INT266900 Gene_expression of Sod2 Negative_regulation of Gene_expression of Sod1 1 0.11 0.41 0.11 100.00
11 INT287886 Negative_regulation of THEMIS Negative_regulation of PRKCA 1 0.00 1.19 0.08 99.92
12 INT61359 TNF Positive_regulation of NFKB1 11 0.63 6.66 3.89 99.84
13 INT103131 Positive_regulation of NFKB1 Regulation of Gene_expression of IL8 1 0.27 0.68 0.4 99.84
14 INT103130 DCSTAMP Positive_regulation of Gene_expression of IL8 1 0.09 0.65 0.39 99.84
15 INT103133 TNF Positive_regulation of Gene_expression of IL8 2 0.48 1.26 0.96 99.84
16 INT330976 Igh-Dex Positive_regulation of Gene_expression of VDR 1 0.01 1.11 0.23 99.84
17 INT103557 Binding of ERCC2 and TP53 1 0.40 1 0.13 99.80
18 INT103561 Binding of TP53 and Mc1r 1 0.03 1 0.13 99.80
19 INT134652 Binding of MC1R and SUGT1 1 0.02 0.84 0.68 99.76
20 INT66020 Binding of Mc1r and RBM25 1 0.00 0.42 0.57 99.76
21 INT121365 ZNF398 Negative_regulation of Gene_expression of MIF 1 0.00 0.73 0.38 99.60
22 INT205160 Binding of CD44 and MMP2 1 0.09 0.61 0.07 99.60
23 INT127995 Binding of RHCE and MINOS1 1 0.03 0.33 0.16 99.56
24 INT351029 AGK Regulation of VEGFA 1 0.00 0.82 0 99.50
25 INT351030 AGK Regulation of ARAF 1 0.00 0.82 0 99.50
26 INT121378 Fancl Positive_regulation of MIF 1 0.01 0.92 0.42 99.48
27 INT5217 Binding of GRDX and Tas2r124 1 0.11 0.37 0.05 99.44
28 INT5216 Binding of GRDX and Ighg3 1 0.42 0.37 0.05 99.44
29 INT276228 Nrtim1 Positive_regulation of PPARG 1 0.01 2.18 0.14 99.38
30 INT103132 Positive_regulation of DCSTAMP Positive_regulation of JUN 1 0.03 0.73 0.43 99.36
31 INT103128 Positive_regulation of DCSTAMP Positive_regulation of NFKB1 1 0.07 0.73 0.43 99.36
32 INT259934 Plat Positive_regulation of Gene_expression of Mmp9 2 0.33 1.05 0.17 99.22
33 INT306513 EDN3 Positive_regulation of EDNRB 1 0.14 0.98 0.04 99.20
34 INT306514 EDN1 Positive_regulation of EDNRB 1 0.11 0.98 0.04 99.20
35 INT178072 Gene_expression of EDNRB Positive_regulation of EDN3 1 0.05 1.11 0.08 99.12
36 INT178100 Gene_expression of EDNRB Positive_regulation of EDN1 1 0.17 1.11 0.08 99.12
37 INT245078 FGF2 Positive_regulation of CXCR4 1 0.07 1.36 0 99.12
38 INT160829 Tyr Regulation of RYBP 1 0.04 0.75 0.53 99.08
39 INT256629 Binding of Ptch1 and Shh 7 0.42 4.22 0.19 98.76
40 INT270464 Binding of Shh and Smo 1 0.07 1.3 0.08 98.76
41 INT270459 Binding of Shh and Gli1 1 0.02 0.65 0.04 98.76
42 INT103129 DCSTAMP Positive_regulation of JUN 1 0.03 0.72 0.43 98.74
43 INT103134 DCSTAMP Positive_regulation of NFKB1 2 0.07 1.43 0.7 98.74
44 INT76078 Binding of HLA-A and TNFRSF10A 1 0.34 0.91 0.18 98.72
45 INT133046 TNF Positive_regulation of Positive_regulation of NFKB1 5 0.54 3.23 1.19 98.60
46 INT49242 Binding of Mc1r and Pomc 10 0.38 3.79 2.15 98.60
47 INT42422 Pomc Positive_regulation of Rtcd1 1 0.07 0.35 0.32 98.60
48 INT270457 Binding of Ptch1 and Gli1 1 0.02 1.3 0.08 98.60
49 INT137579 Bms1 Negative_regulation of TNF Positive_regulation of NFKB1 1 0.08 0.42 0.41 98.60
50 INT270458 Binding of Gli1 and Smo 1 0.00 0.65 0.04 98.60
51 INT130803 MC1R Regulation of Positive_regulation of Cdkn2a 1 0.17 0.82 0.34 98.48
52 INT113950 FLNA Regulation of Oprd1 1 0.00 0.16 0.32 98.48
53 INT121364 ZNF398 Negative_regulation of Transcription of MIF 1 0.00 0.9 0.43 98.44
54 INT227670 EGF Positive_regulation of Gene_expression of ISYNA1 1 0.01 2.92 0 98.40
55 INT345197 Gpr87 Regulation of Gpr87 Regulation of Trp53 1 0.00 0.42 0.05 98.40
56 INT345181 Gpr87 Regulation of Trp53 1 0.01 0.42 0.05 98.40
57 INT287879 Binding of WNT5A and FZD5 1 0.06 1.16 0.08 98.24
58 INT97430 Binding of B2M and HLA-B 1 0.00 0.66 0.04 98.12
59 INT352525 SLC25A16 Negative_regulation of SMO 1 0.00 1.1 0 98.00
60 INT205152 Binding of CD44 and MMP9 23 0.35 17.13 1.85 97.84
61 INT133049 TNF Positive_regulation of ICAM1 4 0.47 2.49 0.54 97.84
62 INT15141 MME Negative_regulation of IL1B 1 0.39 0.19 0.32 97.80
63 INT322413 Binding of ATF1 and EWSR1 1 0.26 1.3 0 97.80
64 INT66206 Negative_regulation of TNF Positive_regulation of NFKB1 2 0.53 1.71 0.81 97.68
65 INT66205 TNF Positive_regulation of TNF Positive_regulation of NFKB1 4 0.41 2.74 1.24 97.68
66 INT217151 Gene_expression of MIR98 Negative_regulation of HMGA2 1 0.24 1.08 0 97.56
67 INT316478 Binding of Stat3 and Hist1h3f 1 0.05 1.08 0.03 97.52
68 INT259931 Plat Positive_regulation of Gene_expression of Jun 1 0.08 0.58 0.07 97.48
69 INT260067 Binding of PTCH1 and XPA 1 0.26 1.08 0 97.40
70 INT269209 SNAI1 Regulation of Gene_expression of LOXL2 1 0.07 1.14 0 97.00
71 INT140238 HELQ Regulation of MC1R 1 0.01 0.5 1.2 96.80
72 INT178092 EDN3 Positive_regulation of PTK2 1 0.01 1.02 0.17 96.72
73 INT178073 EDN1 Positive_regulation of PTK2 1 0.03 1.02 0.17 96.72
74 INT353435 Binding of Pdpk1 and Rock1 1 0.09 0.27 0 96.60
75 INT169611 Binding of RAN and OGFR 1 0.24 0.19 0.23 96.40
76 INT344310 MAPK8 Positive_regulation of Negative_regulation of VEGFA 1 0.08 0.57 0 96.08
77 INT140236 GRK6 Positive_regulation of Binding of MC1R 1 0.52 0.31 0.68 95.96
78 INT191059 Bcl2 Positive_regulation of Localization of Il12a 1 0.16 0.77 0 95.92
79 INT342038 Binding of Gdnf and Ntn1 1 0.01 0.78 0 95.88
80 INT169616 Binding of OGFR and OR51B4 1 0.03 0.19 0.23 95.84
81 INT61360 Regulation of TNF Positive_regulation of NFKB1 2 0.21 1.34 0.14 95.80
82 INT205155 Negative_regulation of Binding of CD44 and MMP9 1 0.32 1.98 0.23 95.72
83 INT168203 Binding of Mc1r and Msx1 1 0.19 0.64 0.25 95.60
84 INT133050 TNF Positive_regulation of Gene_expression of ICAM1 3 0.67 1.91 0.94 95.52
85 INT140235 ADRBK1 Positive_regulation of Binding of MC1R 1 0.46 0.31 0.68 95.44
86 INT334323 IL8 Positive_regulation of EGFR 1 0.50 1.29 0 95.44
87 INT334319 IL8 Positive_regulation of MAPK1 1 0.25 1.29 0 95.44
88 INT345307 CXCL12 Positive_regulation of Gene_expression of MMP15 1 0.00 2.5 0.05 95.16
89 INT344315 MAPK8 Positive_regulation of Negative_regulation of PDPN 1 0.35 0.56 0 95.12
90 INT342043 Binding of Gdnf and Unc5a 1 0.20 0.78 0 95.04
91 INT342041 Binding of Gfra2 and Unc5a 1 0.27 0.39 0 95.04
92 INT148835 asa Negative_regulation of Tyr 1 0.33 0.58 0.18 94.88
93 INT147727 Phosphorylation of PTK2 Regulation of Positive_regulation of RAC1 1 0.34 0.32 0.14 94.88
94 INT147726 Phosphorylation of PTK2 Regulation of Positive_regulation of PIK3CA 1 0.09 0.32 0.14 94.88
95 INT345162 Dmbx1 Regulation of Gene_expression of Lpar1 1 0.03 0.41 0 94.88
96 INT345153 Dmbx1 Regulation of Enpp2 1 0.00 0.41 0 94.88
97 INT235648 Binding of EFNA1 and EPHA2 1 0.23 1.3 0 94.84
98 INT262756 STAT3 Positive_regulation of NFE2L2 1 0.31 1.55 0 94.52
99 INT106707 POMC Regulation of Binding of LAMB2 1 0.03 0.7 0.94 94.40
100 INT201543 Binding of NPC1 and RNASE1 1 0.07 1.33 0.08 94.40
101 INT128499 KLK7 Regulation of Gene_expression of MC1R 1 0.01 0.09 0.15 94.20
102 INT345372 Col18a1 Positive_regulation of Kdr 1 0.20 1.42 0 93.92
103 INT220527 Nme1 Negative_regulation of Positive_regulation of Vegfa 1 0.00 1.23 0.12 93.92
104 INT345149 Enpp2 Regulation of Gene_expression of Lpar1 1 0.01 0.41 0 93.92
105 INT201610 Binding of Mc1r and Braf 1 0.31 0.75 0.42 93.76
106 INT302641 Rac1 Regulation of TIE1 1 0.25 0.47 0 93.60
107 INT102625 IL6 Regulation of Gene_expression of PTGS2 1 0.11 0.29 0.24 93.60
108 INT102620 PTAFR Regulation of Gene_expression of IL6 1 0.24 0.29 0.24 93.60
109 INT102617 PTAFR Regulation of Gene_expression of PTGS2 1 0.12 0.29 0.24 93.60
110 INT259933 Negative_regulation of Akt1 Negative_regulation of Gene_expression of Jun 1 0.01 0.31 0.07 93.44
111 INT344319 MAPK8 Positive_regulation of PDPN 1 0.35 0.5 0 93.20
112 INT201614 Mc1r Regulation of Uvbi1 1 0.04 1.42 0.98 93.16
113 INT290671 Binding of Socs3 and Stat3 2 0.23 1.59 0.45 93.12
114 INT315200 Negative_regulation of Binding of Socs3 and Stat3 1 0.26 1.18 0.27 93.12
115 INT242598 Binding of Gdnf and Gfra2 4 0.16 0.38 0.51 93.08
116 INT133048 TNF Positive_regulation of NFYA 1 0.16 0.69 0.05 92.88
117 INT260070 Binding of PHF2 and SPTLC1 1 0.17 1.93 0.1 92.52
118 INT124385 GRK6 Negative_regulation of MC1R 1 0.42 0.42 0.77 92.48
119 INT124384 ADRBK1 Negative_regulation of MC1R 1 0.40 0.42 0.77 92.48
120 INT102622 PTAFR Regulation of IL6 1 0.24 0.29 0.24 92.36
121 INT353434 Binding of Rock1 and Rnd3 1 0.22 0.26 0 92.12
122 INT344313 PDPN Positive_regulation of VEGFA 1 0.09 0.8 0 91.92
123 INT344311 PDPN Positive_regulation of Negative_regulation of VEGFA 1 0.09 0.81 0 91.92
124 INT169614 Binding of KPNA1 and OGFR 1 0.06 0.18 0.23 91.60
125 INT184522 Positive_regulation of Ptger2 Regulation of Localization of Ccnd1 1 0.01 0.95 0.11 91.04
126 INT184521 Ptger2 Regulation of Localization of Ccnd1 1 0.01 0.94 0.11 91.04
127 INT113946 Binding of FLNA and OPRM1 1 0.10 0.37 0.9 90.96
128 INT344383 Olfr360 Regulation of Gene_expression of Efnb1 1 0.01 1.27 0.74 90.76
129 INT247427 CDKN2A Negative_regulation of Negative_regulation of RB1 1 0.07 1.16 0 90.68
130 INT60328 Il1b Positive_regulation of Tnf 2 0.29 1.84 0.62 90.68
131 INT140841 Il24 Positive_regulation of Gene_expression of GADD45G 1 0.25 1.21 0.51 90.48
132 INT184953 Binding of CDC6 and PCNA 1 0.05 0.19 0.13 90.48
133 INT276948 Tlr2 Negative_regulation of Gene_expression of Tlr4 1 0.25 1.06 0.14 90.44
134 INT345343 PTCH1 Regulation of Negative_regulation of SMO 1 0.09 2.3 0.13 90.32
135 INT293973 Binding of POMC and Mc1r 1 0.37 1.8 0.07 90.32
136 INT178093 EDN3 Positive_regulation of Gene_expression of EDNRB 1 0.05 1.01 0.07 90.28
137 INT178096 EDN1 Positive_regulation of Gene_expression of EDNRB 1 0.17 1.01 0.07 90.28
138 INT102762 Binding of POMC and TYR 1 0.12 0.35 0.69 90.28
139 INT158506 COX5A Negative_regulation of PTGS1 1 0.06 0.18 0 90.28
140 INT127996 Binding of POMC and MINOS1 1 0.02 0.17 0.08 90.24
141 INT270462 Shh Positive_regulation of Ccnd1 1 0.10 0.6 0.03 90.24
142 INT262752 IGHA1 Positive_regulation of IGKV2D-19 1 0.00 1.39 0 90.16
143 INT319787 Binding of Dio1 and Ccbp2 1 0.06 0.92 0.03 90.16
144 INT184520 Ptger2 Regulation of Ccnd1 1 0.00 0.94 0.11 89.68
145 INT106706 POMC Negative_regulation of Binding of FN1 1 0.19 0.79 1.02 89.36
146 INT68852 MC1R Positive_regulation of Localization of POMC 1 0.31 0.47 0.19 89.16
147 INT68853 MC1R Regulation of Localization of POMC 1 0.30 0.47 0.19 89.16
148 INT337087 Negative_regulation of Binding of Mif and Cops5 1 0.13 1.64 0.08 89.12
149 INT337084 Negative_regulation of Binding of Cd74 and Mif 1 0.29 1.64 0.08 89.12
150 INT337088 Binding of Mif and Cops5 1 0.12 1.63 0.08 89.12
151 INT195773 Binding of Cd74 and Mif 2 0.25 2.78 0.55 89.12
152 INT330384 IER3 Regulation of USH2A 1 0.00 0.87 0 89.08
153 INT64637 Binding of CSF2 and SNORD114-18 1 0.05 1.13 0.24 89.04
154 INT156144 MLL Positive_regulation of Epcam 1 0.00 0.47 0.06 88.96
155 INT119045 HIF1A Regulation of Regulation of TP53 1 0.09 1.06 0 88.88
156 INT119046 HIF1A Regulation of TP53 1 0.05 1.06 0 88.88
157 INT119044 HIF1A Regulation of TCEAL1 1 0.02 1.06 0 88.88
158 INT119047 HIF1A Regulation of Regulation of TCEAL1 1 0.08 1.06 0 88.88
159 INT226517 Binding of IL19 and Il20ra 1 0.00 0.69 0.53 88.72
160 INT226349 Binding of IL19 and IL20RA 1 0.00 0.24 0.19 88.72
161 INT226357 Binding of IL24 and IL19 1 0.01 0.23 0.16 88.72
162 INT345486 PMAIP1 Positive_regulation of Localization of CYC1 1 0.18 0.96 0 88.56
163 INT201618 Uvbi1 Positive_regulation of Phb 1 0.04 0.28 0.09 88.52
164 INT79163 Binding of PLG and CLEC3B 2 0.29 3.18 0 88.44
165 INT156143 MLL Positive_regulation of PECAM1 1 0.00 0.47 0.06 88.40
166 INT266412 Binding of S100A12 and Ager 1 0.01 1.03 0.15 88.40
167 INT226540 Binding of IL24 and Il20ra 1 0.00 0.97 0.71 88.32
168 INT351032 Binding of CD80 and CD96 1 0.01 0.36 0.09 88.32
169 INT351031 Binding of CD28 and CD96 1 0.02 0.36 0.09 88.32
170 INT226345 Binding of IL24 and IL20RA 1 0.00 0.23 0.19 88.32
171 INT96563 Binding of ADRA1D and UCN2 1 0.19 1.34 0.1 88.32
172 INT69872 Binding of MC1R and POMC 52 0.54 8.87 18.3 87.92
173 INT314745 Binding of TP53 and Brca1 1 0.18 1.17 0 87.92
174 INT312693 Binding of CCR6 and CCL20 2 0.34 2.33 0.53 87.60
175 INT107726 BIRC2 Regulation of ASIP 1 0.03 0.24 0.35 87.60
176 INT149117 Binding of CD80 and CTLA4 31 0.52 12.7 7.73 87.36
177 INT186126 Binding of CD28 and CTLA4 9 0.52 4.13 3.12 87.36
178 INT262758 MRGPRF Positive_regulation of Transcription of NFE2L3 1 0.01 1.25 0.09 87.36
179 INT345169 Lpar1 Negative_regulation of Dmbx1 1 0.08 2.26 0.08 87.28
180 INT194647 Binding of CD28 and CD80 15 0.40 4.9 3.22 87.08
181 INT73832 Pld1 Positive_regulation of ADCY1 1 0.00 0.16 0.44 87.08
182 INT168202 Msx1 Negative_regulation of Gene_expression of Mc1r 1 0.21 0.49 0.35 86.88
183 INT97655 Binding of RBM25 and Mc1r 1 0.00 0.44 0.58 86.56
184 INT201609 Uvbi1 Positive_regulation of Gene_expression of Mc1r 1 0.05 0.57 0.17 86.56
185 INT280163 Twist1 Positive_regulation of Mod2 1 0.07 1.67 0 86.48
186 INT301402 Enpp2 Positive_regulation of Lpar1 2 0.33 0.55 0.07 86.48
187 INT345189 Dmbx1 Positive_regulation of Lpar1 1 0.06 0.23 0 86.48
188 INT154538 SF Regulation of Gene_expression of PPY 1 0.11 1 0.14 86.08
189 INT185455 MUC1 Negative_regulation of Timp1 1 0.06 0.84 0.13 86.00
190 INT185454 IGHG1 Negative_regulation of Timp1 1 0.04 0.85 0.13 86.00
191 INT318189 MUC5AC Regulation of Gene_expression of VEGFA 1 0.21 1.17 0.22 85.92
192 INT107722 ASIP Negative_regulation of EIF4E1B 1 0.02 0.43 0.07 85.88
193 INT298684 ecs Positive_regulation of Gene_expression of KDR 1 0.01 1.2 0 85.76
194 INT354923 Binding of VDR and Uvbs1 1 0.00 0.83 0 85.68
195 INT198022 AKT1 Regulation of Gene_expression of MCL1 1 0.15 2.25 0 85.64
196 INT198020 PIK3CA Regulation of Gene_expression of MCL1 1 0.16 2.25 0 85.64
197 INT107727 ASIP Negative_regulation of RRM2 1 0.29 0.43 0.07 85.56
198 INT148836 asa Negative_regulation of Gene_expression of Tyr 1 0.43 0.52 0.16 85.48
199 INT185416 MUC1 Negative_regulation of TIMP1 1 0.18 0.84 0.13 85.44
200 INT185418 IGHG1 Negative_regulation of TIMP1 1 0.11 0.84 0.13 85.44

Single Events

The table below shows the top 200 pain related interactions that have been reported for Skin Cancer. They are ordered first by their pain relevance and then by number of times they were reported in Skin Cancer. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT21737 Binding of MC1R 129 0.48 45.45 56.54 100.00
2 INT56130 Gene_expression of MC1R 259 0.78 62.7 97.55 100.00
3 INT284765 Gene_expression of BCC1 22 0.56 29.32 0.14 100.00
4 INT195206 Binding of BCC1 15 0.41 21.3 0.62 100.00
5 INT867 Gene_expression of IFNA1 930 0.78 594.85 168.03 100.00
6 INT62169 Positive_regulation of MC1R 72 0.69 14.56 27.52 100.00
7 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 100.00
8 INT18522 Positive_regulation of Gene_expression of IFNA1 248 0.67 160.85 44.87 100.00
9 INT79395 Gene_expression of Twist1 193 0.77 100.06 26.34 100.00
10 INT180265 Localization of BCC1 7 0.65 9.48 0.15 100.00
11 INT78472 Gene_expression of CDKN2A 223 0.78 173.76 13.61 100.00
12 INT284762 Positive_regulation of Gene_expression of BCC1 1 0.42 2.94 0 100.00
13 INT119700 Gene_expression of VDR 88 0.75 65.33 11.5 100.00
14 INT180264 Positive_regulation of BCC1 11 0.59 12.81 0.2 100.00
15 INT71030 Binding of Mc1r 39 0.48 10.27 12.02 100.00
16 INT68288 Positive_regulation of SERPINB3 14 0.51 16.87 0.41 100.00
17 INT81345 Gene_expression of ADRBK1 21 0.70 2.89 7.9 100.00
18 INT181177 Gene_expression of CYLD 5 0.69 24.96 0.89 100.00
19 INT71644 Gene_expression of MLANA 16 0.75 11.55 1.82 100.00
20 INT68285 Gene_expression of SERPINB3 24 0.75 25.4 0.45 100.00
21 INT153419 Regulation of Binding of MC1R 1 0.40 1.38 0.7 100.00
22 INT284763 Positive_regulation of Gene_expression of CELP 1 0.17 1.51 0 100.00
23 INT185452 Regulation of CYLD 6 0.40 6.09 0.21 100.00
24 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73 100.00
25 INT124389 Gene_expression of GRK6 3 0.70 1.14 2.16 100.00
26 INT117033 Gene_expression of JAG1 13 0.65 11.46 1.52 100.00
27 INT126714 Binding of Xpc 1 0.34 1.69 0.1 100.00
28 INT68094 Negative_regulation of SERPINB3 12 0.43 10.55 1.49 100.00
29 INT284764 Positive_regulation of Transcription of BCC1 1 0.42 1.58 0 100.00
30 INT284767 Transcription of BCC1 1 0.57 1.58 0 100.00
31 INT182968 Positive_regulation of Gene_expression of VDR 22 0.58 15.22 0.89 100.00
32 INT102969 Positive_regulation of Gene_expression of ADRBK1 7 0.46 1.21 2.87 100.00
33 INT231978 Binding of SERPINB3 9 0.36 8.33 0 100.00
34 INT109403 Regulation of Gene_expression of BCL2 31 0.60 31.22 3.4 100.00
35 INT185449 Regulation of Regulation of CYLD 1 0.21 2.03 0.13 100.00
36 INT309533 Negative_regulation of BCC1 3 0.25 2.62 0.03 100.00
37 INT130143 Gene_expression of S100A10 5 0.68 6.48 1.47 100.00
38 INT137430 Gene_expression of ALOX15B 1 0.78 5.19 1.9 100.00
39 INT68683 Regulation of Gene_expression of VEGFA 143 0.62 104.19 20.14 100.00
40 INT86823 Regulation of Transcription of PTGS2 3 0.19 1.48 1.4 100.00
41 INT68855 Gene_expression of PTPRJ 9 0.65 2.99 0.16 100.00
42 INT276224 Binding of Nrtim1 1 0.01 1.3 0.23 100.00
43 INT356395 Gene_expression of Ascc1 1 0.02 1.72 0 100.00
44 INT116540 Binding of Twist1 35 0.48 16.32 2.85 100.00
45 INT121366 Regulation of Transcription of Mif 1 0.02 0.61 0.24 100.00
46 INT60073 Negative_regulation of Binding of Il2 2 0.42 1.03 0.09 100.00
47 INT9235 Negative_regulation of Gene_expression of TNF 346 0.59 252.98 118.61 100.00
48 INT106318 Gene_expression of S100A4 21 0.75 12.13 3.23 100.00
49 INT8547 Gene_expression of MUC16 116 0.78 75.97 12.18 100.00
50 INT11154 Binding of EGFR 149 0.48 96.23 6.29 100.00
51 INT170333 Binding of IFN1@ 68 0.47 49.01 9.72 100.00
52 INT57749 Negative_regulation of Gene_expression of TP53 39 0.56 36.79 4.45 100.00
53 INT53196 Binding of Cd4 44 0.47 27.28 5.85 100.00
54 INT308400 Negative_regulation of Regulation of CDKN2A 1 0.40 0.87 0 100.00
55 INT4465 Gene_expression of CEL 116 0.77 98.35 23.58 100.00
56 INT18995 Binding of CEL 23 0.47 14.46 4.5 100.00
57 INT166379 Gene_expression of Araf 11 0.49 5.2 0.9 100.00
58 INT156501 Gene_expression of MAGEA1 8 0.18 10.26 0.08 100.00
59 INT191161 Gene_expression of CIITA 4 0.55 4.35 0.17 100.00
60 INT352526 Protein_catabolism of BCC1 1 0.51 0.65 0 100.00
61 INT185437 Negative_regulation of Gene_expression of CYLD 3 0.52 2.41 0.05 100.00
62 INT822 Gene_expression of ESR1 529 0.78 302.16 63.64 100.00
63 INT140828 Positive_regulation of Il24 4 0.31 3.55 1.43 100.00
64 INT8548 Gene_expression of HP 86 0.77 47.62 11.94 100.00
65 INT185432 Negative_regulation of CYLD 4 0.52 3.19 0.35 100.00
66 INT185440 Negative_regulation of Negative_regulation of CYLD 1 0.20 1.02 0.08 100.00
67 INT89445 Gene_expression of MEPE 17 0.58 18.07 1.55 100.00
68 INT91070 Regulation of GSR 27 0.59 16.64 3.42 100.00
69 INT125100 Positive_regulation of IL24 4 0.65 7.15 1.57 100.00
70 INT27242 Gene_expression of PGR 153 0.75 98.77 12.79 100.00
71 INT152642 Gene_expression of LGALS3BP 1 0.67 3.28 0.3 100.00
72 INT152648 Positive_regulation of Gene_expression of LGALS3BP 1 0.43 3.29 0.3 100.00
73 INT233642 Regulation of Mcam 1 0.51 0.91 1.24 100.00
74 INT81194 Binding of CPOX 40 0.29 23.7 18.95 100.00
75 INT90607 Positive_regulation of Binding of CPOX 4 0.17 0.79 0.67 100.00
76 INT99524 Gene_expression of IFIH1 34 0.64 23.38 2.24 100.00
77 INT137450 Positive_regulation of Positive_regulation of HEPN1 1 0.00 0.2 0.07 100.00
78 INT137449 Positive_regulation of HEPN1 2 0.01 1.46 0.16 100.00
79 INT276939 Positive_regulation of Phosphorylation of Tlr2 1 0.46 0.6 0.03 100.00
80 INT276931 Phosphorylation of Tlr2 1 0.75 0.6 0.03 100.00
81 INT214073 Binding of TSC1 9 0.37 22 1.34 100.00
82 INT8540 Gene_expression of Serpina1a 5 0.66 3.99 0.34 100.00
83 INT8541 Gene_expression of Csrp1 42 0.76 23.72 6.9 100.00
84 INT172551 Negative_regulation of INCENP 38 0.07 20.83 3.14 100.00
85 INT46637 Gene_expression of CXCL10 172 0.78 121.94 57.74 100.00
86 INT92237 Positive_regulation of Gene_expression of CXCL10 43 0.70 43.67 13.65 100.00
87 INT81796 Binding of AGRP 62 0.36 37.19 5.3 100.00
88 INT137178 Gene_expression of TLR3 46 0.72 24.97 4.33 100.00
89 INT215897 Gene_expression of Mcam 10 0.75 4.68 0.81 100.00
90 INT188775 Binding of IFIH1 11 0.16 12.4 0.61 100.00
91 INT152647 Gene_expression of IRF7 2 0.57 4 0.4 100.00
92 INT181179 Binding of CYLD 4 0.43 7.06 0.39 100.00
93 INT152643 Positive_regulation of Gene_expression of IFIH1 5 0.42 5.2 0.28 100.00
94 INT152646 Positive_regulation of Gene_expression of IRF7 2 0.37 2.54 0.2 100.00
95 INT152644 Positive_regulation of Gene_expression of MAGEB5 1 0.14 1.62 0.15 100.00
96 INT152645 Gene_expression of MAGEB5 1 0.21 1.62 0.15 100.00
97 INT119645 Regulation of 94B16F 2 0.40 0.49 0.09 100.00
98 INT84712 Regulation of MC1R 36 0.62 9.34 16.91 99.98
99 INT5058 Positive_regulation of IFNA1 356 0.70 245.75 60.52 99.98
100 INT69264 Gene_expression of KIT 207 0.78 179.41 8.95 99.98
101 INT11918 Localization of CGB 35 0.51 8.21 15.01 99.98
102 INT8145 Localization of CGB5 13 0.74 3.68 6.47 99.98
103 INT151134 Regulation of Mchr1 1 0.00 1.12 0.18 99.98
104 INT11235 Positive_regulation of IFNA2 27 0.69 15.32 2.57 99.98
105 INT86901 Negative_regulation of Mia 3 0.37 2.11 1.67 99.98
106 INT12341 Positive_regulation of Arigg2 1 0.08 0.57 0.16 99.98
107 INT73625 Gene_expression of PPARG 108 0.78 104.85 21.42 99.96
108 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 99.96
109 INT113948 Gene_expression of FLNA 32 0.73 36.06 4.81 99.96
110 INT745 Gene_expression of Afp 65 0.78 52.89 4.24 99.96
111 INT232991 Localization of KRT5 1 0.33 1.36 0.04 99.96
112 INT160852 Regulation of CD55 5 0.16 5.28 0.56 99.96
113 INT209948 Gene_expression of CLEC3B 3 0.78 11.51 0.6 99.92
114 INT97264 Binding of Mc1r 9 0.36 4.27 4.53 99.92
115 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 99.92
116 INT11051 Positive_regulation of Gene_expression of IL6 415 0.69 319.21 109.3 99.92
117 INT256921 Regulation of Top2a 1 0.21 1.28 0 99.92
118 INT169620 Localization of SERPINB3 3 0.55 0.46 0.28 99.92
119 INT287929 Negative_regulation of THEMIS 1 0.01 2.44 0.3 99.92
120 INT311026 Positive_regulation of Mcam 2 0.49 0.3 0.03 99.92
121 INT62426 Gene_expression of Mc1r 127 0.78 42.99 48.01 99.90
122 INT17331 Positive_regulation of JUN 132 0.69 60.4 27.03 99.90
123 INT94774 Regulation of CDKN2A 43 0.60 44.41 13.99 99.90
124 INT83797 Gene_expression of Bcl2l1 124 0.77 94.55 22.39 99.90
125 INT71789 Positive_regulation of MAPK1 396 0.70 234.44 89.27 99.90
126 INT49325 Gene_expression of Cd34 102 0.78 82.75 8.97 99.90
127 INT82685 Gene_expression of Pecam1 36 0.76 27.95 9.01 99.90
128 INT126941 Binding of OCA2 2 0.42 1.31 0.07 99.90
129 INT9900 Positive_regulation of Vwf 80 0.69 51.85 18.13 99.90
130 INT9899 Gene_expression of Vwf 91 0.74 45.06 9.13 99.90
131 INT67379 Positive_regulation of Cd34 38 0.58 26.18 3.28 99.90
132 INT82684 Positive_regulation of Pecam1 27 0.49 25.67 11.47 99.90
133 INT78471 Regulation of Gene_expression of CDKN2A 13 0.45 12.52 3.28 99.90
134 INT130765 Positive_regulation of ERAL1 7 0.49 7.07 1.54 99.90
135 INT1649 Localization of CSH1 15 0.46 3.65 5.75 99.90
136 INT13139 Negative_regulation of Cd4 27 0.47 17.49 6.61 99.90
137 INT97621 Negative_regulation of Cd8a 3 0.24 3.08 1.77 99.90
138 INT182408 Localization of ERCC6 4 0.72 2.31 0.14 99.90
139 INT86024 Gene_expression of PPARA 736 0.78 497.93 91.14 99.88
140 INT146545 Negative_regulation of Gene_expression of MSH2 17 0.56 18.87 0.51 99.88
141 INT178127 Positive_regulation of Gene_expression of EDNRB 7 0.51 5.24 0.78 99.88
142 INT84891 Gene_expression of PPARD 10 0.78 6.8 3.64 99.88
143 INT84889 Positive_regulation of Gene_expression of PPARD 4 0.70 2.94 1.49 99.88
144 INT70273 Gene_expression of CALB2 9 0.75 7.85 2.54 99.88
145 INT116856 Gene_expression of TNFSF10 110 0.75 115.76 21.48 99.88
146 INT467 Gene_expression of POMC 1048 0.78 332.8 394.16 99.86
147 INT85640 Gene_expression of Tg(CAG-EGFP)D4Nagy 1138 0.72 311.58 119.18 99.86
148 INT194462 Localization of Ppara 94 0.78 68.33 12.09 99.86
149 INT4988 Gene_expression of KRT1 64 0.77 43.4 4.12 99.86
150 INT232994 Gene_expression of KRT10 6 0.40 8.2 0.03 99.86
151 INT93715 Negative_regulation of MMP9 69 0.55 36.05 11.73 99.86
152 INT57645 Gene_expression of GSTK1 54 0.62 21.05 4.2 99.86
153 INT153406 Gene_expression of Cxcl16 18 0.72 6.16 2.16 99.86
154 INT67568 Positive_regulation of Localization of MMP2 14 0.31 8.58 6.79 99.86
155 INT185433 Regulation of CTTNBP2NL 1 0.06 1.4 0.04 99.86
156 INT65960 Gene_expression of BCL2 352 0.78 312.03 30.73 99.84
157 INT54571 Positive_regulation of NFKB1 263 0.70 138.99 87.32 99.84
158 INT10832 Gene_expression of IL8 1050 0.78 698.72 270 99.84
159 INT2385 Gene_expression of MIF 57 0.68 40.74 12.78 99.84
160 INT269217 Gene_expression of SNAI1 81 0.76 80.49 2.26 99.84
161 INT62464 Gene_expression of Ogfr 21 0.78 20.39 10.82 99.84
162 INT121372 Positive_regulation of Gene_expression of MIF 17 0.60 14.78 4.73 99.84
163 INT11159 Gene_expression of EGFR 698 0.78 548.93 25.69 99.84
164 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 99.84
165 INT77652 Negative_regulation of Gene_expression of IL8 99 0.59 67.57 30.21 99.84
166 INT111476 Gene_expression of TP63 88 0.76 61.08 11.64 99.84
167 INT111607 Gene_expression of CDH1 103 0.75 90.45 7.77 99.84
168 INT54572 Negative_regulation of Positive_regulation of NFKB1 46 0.58 21.45 15.47 99.84
169 INT50670 Gene_expression of CPOX 763 0.76 442.13 195.02 99.84
170 INT66210 Regulation of Positive_regulation of NFKB1 16 0.60 9.46 7.08 99.84
171 INT135727 Positive_regulation of Gene_expression of Mc1r 18 0.69 8.69 4.92 99.84
172 INT119708 Transcription of VDR 11 0.71 5.43 0.48 99.84
173 INT5788 Gene_expression of IL2RA 60 0.75 40.67 9.98 99.84
174 INT66208 Positive_regulation of Positive_regulation of NFKB1 45 0.68 20.17 22.62 99.84
175 INT11587 Gene_expression of CSF2 645 0.78 544.38 93.89 99.84
176 INT11560 Positive_regulation of CASP3 236 0.70 184.33 39.38 99.84
177 INT97280 Gene_expression of Tk1 11 0.77 16.17 1.32 99.84
178 INT27096 Positive_regulation of Nfkb1 325 0.70 195.11 109.06 99.84
179 INT119702 Transcription of CYP24A1 4 0.69 1.61 0.16 99.84
180 INT146179 Gene_expression of KRT6A 23 0.75 9.39 0.52 99.84
181 INT10833 Regulation of Gene_expression of IL8 68 0.62 38.74 18.46 99.84
182 INT92141 Negative_regulation of CDKN2A 53 0.57 44.23 2.48 99.84
183 INT62422 Regulation of Gene_expression of Mc1r 12 0.62 2.28 5.93 99.84
184 INT11158 Positive_regulation of Gene_expression of EGFR 165 0.70 131.26 4.93 99.84
185 INT139237 Negative_regulation of Gene_expression of CDH1 23 0.57 24.31 1.28 99.84
186 INT129934 Gene_expression of G6PC 3 0.57 5.3 0.35 99.84
187 INT18357 Gene_expression of TRPV1 825 0.78 307.11 382.81 99.84
188 INT2640 Gene_expression of Pomc 424 0.78 120.72 155.37 99.84
189 INT117116 Positive_regulation of Positive_regulation of MC1R 7 0.49 1.57 1.91 99.84
190 INT26500 Gene_expression of MMP2 201 0.78 110.57 46.9 99.84
191 INT102749 Positive_regulation of Positive_regulation of CASP3 32 0.67 26.07 6.93 99.84
192 INT121374 Regulation of Gene_expression of MIF 2 0.39 1.01 0.29 99.84
193 INT103096 Regulation of PPARA 113 0.60 62.47 14.57 99.84
194 INT86639 Gene_expression of KRT16 19 0.68 12.44 7.79 99.84
195 INT100603 Gene_expression of DCSTAMP 7 0.22 3.05 2.25 99.84
196 INT97450 Gene_expression of Mitf 36 0.75 17.22 0.39 99.84
197 INT112001 Binding of Cdkn2a 1 0.24 0.35 0.1 99.84
198 INT70776 Positive_regulation of P2rx1 62 0.62 32.55 30.75 99.84
199 INT11747 Positive_regulation of IL2RA 22 0.67 16.55 6.95 99.84
200 INT83602 Positive_regulation of Gene_expression of TRPV1 114 0.70 51.19 56.35 99.84
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