D:Sleep Disorders

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Disease Term
Synonyms Advanced Sleep Phase Syndrome, Alpha Delta Sleep, Apnea, Cataplexy, Cyclic Alternating Pattern, Daytime Sleepiness, Daytime Somnolence, DELAYED SLEEP PHASE SYNDROME, Drowsiness, Dysomnia, Excessive Daytime Somnolence
Documents 16433
Hot Single Events 200
Hot Interactions 80

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Sleep Disorders. They are ordered first by their relevance to Sleep Disorders and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT256897 IGKV1D-39 Regulation of BAG3 1 0.04 1.77 0.94 100.00
2 INT103905 Gh Positive_regulation of Positive_regulation of Crh 1 0.08 0.9 0.66 100.00
3 INT267644 Binding of Das and RLS 1 0.06 1.04 0.35 100.00
4 INT146997 Binding of PLXNA3 and RLS 1 0.36 0.47 0.1 100.00
5 INT258146 Binding of IGFBP3 and Hcrt 1 0.23 2.04 0 99.62
6 INT258086 Binding of CSF2 and IGFBP3 1 0.05 1.18 0 99.62
7 INT275798 Pag1 Regulation of Rem1 1 0.11 0.41 0 99.56
8 INT258906 Binding of HLA-B and HLA-DRB1 1 0.31 1.36 0.15 99.52
9 INT336574 Binding of CD40LG and HCRTR1 1 0.05 0.1 0 99.40
10 INT258143 Binding of Hcrt and Atxn3 1 0.15 1.93 0.08 99.28
11 INT213608 Binding of PER2 and CLOCK 1 0.22 0.65 0.04 99.00
12 INT213607 Binding of CSNK1D and CLOCK 1 0.27 0.65 0.04 99.00
13 INT257467 Fat1 Regulation of Gene_expression of Adipoq 1 0.08 0.56 0.11 98.80
14 INT336576 Binding of HCRTR1 and IGHG3 1 0.01 5.01 0 98.76
15 INT291467 Binding of Hcrt and Hcrtr1 1 0.53 0.87 0.07 98.76
16 INT266100 Binding of COMT and SH2B2 1 0.25 1.22 0.74 98.68
17 INT258144 IGFBP3 Regulation of Gene_expression of Hcrt 1 0.30 2.23 0.03 98.52
18 INT266108 Binding of COMT and HPS1 1 0.23 1.21 0.74 98.36
19 INT273024 Binding of FXYD1 and RLS 1 0.04 1.24 0.21 98.16
20 INT256605 FPR1 Positive_regulation of MTOR 1 0.01 2.18 0 98.04
21 INT258145 IGFBP3 Regulation of Hcrt 1 0.16 0.56 0 97.08
22 INT69280 Negative_regulation of Binding of TSPO and Gabrg1 1 0.00 1.03 0.63 96.92
23 INT275802 Hcrt Regulation of Rem1 1 0.20 0.95 0.17 96.76
24 INT56520 DDX21 Positive_regulation of Localization of Gh 1 0.11 0.16 0.6 96.52
25 INT69279 Regulation of Binding of TSPO and Gabrg1 1 0.00 2.05 1.26 96.48
26 INT182659 Positive_regulation of Gins4 Positive_regulation of Rem1 1 0.00 0.1 0.15 96.40
27 INT348137 Binding of GYPE and Gpi 1 0.01 1.29 0.29 95.80
28 INT175393 Binding of Ugcg and Ssr1 1 0.04 0.6 0.03 95.64
29 INT275803 Hcrt Negative_regulation of Rem1 1 0.19 0.35 0.1 95.48
30 INT258861 Binding of HLA-DOA and HLA-DRB1 2 0.14 1.88 0.28 95.48
31 INT258909 Binding of HLA-DOA and NDUFA2 1 0.03 1.44 0.15 95.48
32 INT69278 Binding of TSPO and Gabrg1 1 0.00 1.01 0.62 95.20
33 INT310547 Binding of TCN1 and ERLIN1 1 0.00 0.17 0.05 95.04
34 INT189127 Mch Positive_regulation of Ahr 1 0.18 0.29 0 94.88
35 INT37157 Pir Positive_regulation of Kncn 1 0.01 0.38 0.3 94.80
36 INT213606 CLOCK Regulation of Gene_expression of PROK2 1 0.20 0.3 0 94.28
37 INT213609 CLOCK Regulation of PROK2 1 0.20 0.3 0 94.28
38 INT169557 Cacna1h Positive_regulation of Mapk1 1 0.07 0.91 1.17 94.28
39 INT327808 EPO Regulation of VEGFA 1 0.07 1.36 0.12 93.64
40 INT145577 Regulation of Binding of Adra2c and Hcn2 1 0.25 0.19 0.4 93.02
41 INT145574 Regulation of Binding of Adra2c and Hcn4 1 0.26 0.19 0.4 93.02
42 INT87061 Binding of AVP and IL6 1 0.26 1.04 0.22 93.00
43 INT145576 Binding of Adra2c and Hcn4 1 0.21 0.19 0.4 92.78
44 INT145575 Binding of Adra2c and Hcn2 1 0.21 0.19 0.4 92.78
45 INT229602 Binding of ETFA and DIS3 1 0.08 1.12 0 92.40
46 INT258147 IGFBP3 Negative_regulation of Hcrt 1 0.28 1.87 0.11 92.28
47 INT125389 Regulation of Flvcr2 Positive_regulation of Fbxo23 1 0.03 0.27 0.44 92.12
48 INT125388 Flvcr2 Positive_regulation of Fbxo23 1 0.05 0.27 0.42 92.12
49 INT258140 Negative_regulation of Binding of Hcrt and Gopc 1 0.07 0.94 0.06 92.00
50 INT264841 NAMPT Positive_regulation of GRM5 1 0.01 0.72 0.27 91.72
51 INT229601 Binding of DIS3 and RLS 1 0.14 2.19 0.06 90.88
52 INT258141 Binding of Hcrt and Gopc 1 0.06 0.93 0.06 90.56
53 INT275799 Binding of Hcrt and Lynx1 1 0.01 0.34 0.07 89.80
54 INT267799 Binding of RLS and ADHD1 1 0.00 4.84 0.14 89.40
55 INT327806 Binding of ADORA1 and ADORA2A 1 0.06 0.18 0.49 88.40
56 INT235594 Binding of LIFR and Rem1 1 0.02 0.36 0 88.32
57 INT193480 Binding of ABCA1 and IRF6 1 0.00 1.08 0.46 88.24
58 INT314484 TH Positive_regulation of RLS 1 0.01 1.66 0.29 87.44
59 INT3591 Negative_regulation of INS Positive_regulation of AVP 1 0.04 0.28 0.2 87.08
60 INT262367 Tcas1 Positive_regulation of Localization of Adh4 1 0.01 1.91 1.01 86.92
61 INT149652 Zfp36 Regulation of Nos2 1 0.09 0.42 0.47 86.88
62 INT290614 Binding of Th and RLS 1 0.21 3.26 0.31 86.84
63 INT258151 IGFBP3 Negative_regulation of Binding of Hcrt 1 0.28 0.49 0 86.84
64 INT3592 INS Positive_regulation of AVP 1 0.05 0.28 0.2 86.36
65 INT253831 Cck Positive_regulation of Gene_expression of Cartpt 1 0.48 0.23 0.69 85.96
66 INT328298 GHRH Negative_regulation of Localization of GHS 1 0.08 0.84 0 85.08
67 INT328296 GHRH Negative_regulation of Localization of GH1 1 0.03 0.84 0 85.08
68 INT258087 Negative_regulation of ANTXR2 Negative_regulation of Gene_expression of IGFBP3 1 0.04 0.29 0 84.84
69 INT220288 MARS Regulation of AFM 1 0.06 1.14 0.08 84.72
70 INT77982 Binding of YY1 and Oprm1 2 0.17 0.17 1.06 84.00
71 INT267707 Binding of Tnf and ARID1B 2 0.20 8.2 0.54 82.48
72 INT72264 Binding of Hrh1 and Hrh3 1 0.11 0.16 0.34 82.00
73 INT340301 Ea1 Positive_regulation of Gene_expression of ACOX1 1 0.01 0.72 0.4 81.84
74 INT258148 Gene_expression of IGFBP3 Negative_regulation of Hcrt 1 0.28 0.86 0.04 81.16
75 INT258152 IGFBP3 Regulation of Transcription of Hcrt 1 0.40 0.42 0 81.04
76 INT249045 CENPJ Regulation of Regulation of LEP 1 0.14 0.81 0 80.48
77 INT275797 Binding of Hcrt and Pag1 1 0.20 0.14 0.16 80.24
78 INT288266 Binding of AFA and CRYGD 1 0.08 1.85 0.64 80.24
79 INT340300 Ea1 Positive_regulation of Gene_expression of Sirt1 1 0.08 1.68 1.49 80.20
80 INT340298 Ea1 Positive_regulation of Ppargc1a 1 0.05 1.03 0.64 80.20
81 INT29119 Nts Regulation of Oprd1 1 0.18 0.79 0.31 79.52
82 INT29118 Trh Regulation of Oprd1 1 0.24 0.79 0.31 79.52
83 INT75247 Abat Regulation of Gene_expression of Tacr1 1 0.23 0.41 1.03 78.24
84 INT56181 sch Regulation of Positive_regulation of Nppa 1 0.07 0.08 0.14 78.20
85 INT34837 Maob Regulation of Negative_regulation of Mme 1 0.48 0.15 0.92 77.96
86 INT240729 Binding of CRP and HLA-A 1 0.11 2.18 0.71 77.68
87 INT262185 Positive_regulation of Binding of Ncoa1 and Nr1i2 1 0.04 0.56 0.12 77.24
88 INT66535 Binding of Pnoc and Oprl1 43 0.54 5.93 32.4 77.12
89 INT183781 Binding of IL6 and INS 6 0.22 8.97 1.87 77.12
90 INT262146 Binding of Ncoa1 and Nr1i2 1 0.03 0.56 0.11 76.92
91 INT19512 Prl Positive_regulation of Odc1 1 0.01 0.89 0.31 76.80
92 INT223482 CRP Positive_regulation of GOPC 1 0.08 0.8 0.1 76.52
93 INT75370 Positive_regulation of Binding of Hrh1 and RGD735065 1 0.00 0.56 1.41 75.88
94 INT75371 Binding of Hrh1 and RGD735065 1 0.00 0.55 1.4 75.32
95 INT349345 Bdnf Negative_regulation of Positive_regulation of Casp3 1 0.13 1.02 0.12 75.04
96 INT277192 SUGT1 Positive_regulation of Gene_expression of SLC6A4 1 0.01 0.86 1.04 74.96
97 INT258149 IGFBP3 Negative_regulation of Gene_expression of Hcrt 1 0.38 1.1 0 74.44
98 INT242324 Lep Regulation of Gene_expression of Ucp1 1 0.58 1.47 0.09 74.40
99 INT118786 Binding of KIAA0101 and NANS 1 0.28 4.67 0.3 73.08
100 INT274094 EDN1 Positive_regulation of AGT 1 0.16 0.95 0.2 73.04
101 INT350016 Binding of CD40LG and ARID1B 1 0.01 3.26 0.21 71.76
102 INT189299 Atp6v1e1 Positive_regulation of Htr2a 1 0.01 1.01 1.41 71.68
103 INT264979 Binding of POR and BAG3 1 0.15 0.38 0 71.32
104 INT264978 Binding of BAG3 and GOPC 1 0.18 0.38 0 71.32
105 INT275800 Binding of Sh2d1a and Tacr1 1 0.01 0.29 0.07 71.04
106 INT275801 Binding of Hcrt and Sh2d1a 1 0.03 0.29 0.06 71.04
107 INT19513 Prl Positive_regulation of IL2 1 0.41 0.8 0.27 69.92
108 INT261841 Mastl Positive_regulation of Trpa1 1 0.00 0.82 1.3 69.12
109 INT61824 Binding of SERPINH1 and CRP 1 0.24 0.63 0.08 69.04
110 INT132580 Binding of ADRA2C and Htr1a 1 0.41 0.27 0.45 68.72
111 INT193479 TLR2 Regulation of Binding of IRF6 1 0.04 0.75 0.28 68.40
112 INT267684 Binding of INS and ARID1B 3 0.10 6.08 0.09 68.32
113 INT208410 IGF1 Positive_regulation of TXK 1 0.08 0.9 0.03 66.48
114 INT87060 IL6 Positive_regulation of Localization of AVP 1 0.59 1.01 0.18 66.28
115 INT175729 Binding of ARNTL and PER1 1 0.19 0.07 0 66.08
116 INT175728 Binding of PER1 and CLOCK 1 0.18 0.07 0 66.08
117 INT252032 Binding of Calm1 and DXIum1 1 0.02 0.48 0.13 65.40
118 INT240730 Binding of CRYGD and MTRF1 4 0.03 4.18 1.39 64.36
119 INT327821 GPRC6A Regulation of Gene_expression of Lep 1 0.00 0.5 0.05 64.16
120 INT327822 INCENP Regulation of Gene_expression of Lep 1 0.00 0.5 0.05 64.16
121 INT175732 Binding of ARNTL and ARMC9 1 0.02 0.06 0 63.80
122 INT175730 Binding of CLOCK and ARMC9 1 0.02 0.06 0 63.80
123 INT307627 Binding of BMP1 and CSF2 1 0.01 0.33 0.12 63.64
124 INT223042 AR Positive_regulation of ADCY1 1 0.01 0.41 0.25 63.60
125 INT316109 TEAD1 Regulation of S100B 1 0.00 1.16 0.04 63.52
126 INT350020 ARID1B Regulation of Positive_regulation of Tnf 1 0.04 1.78 0.16 63.12
127 INT350013 ARID1B Regulation of Positive_regulation of NFKB1 1 0.00 1.77 0.16 63.12
128 INT258170 Binding of Adora1 and Ppap2a 1 0.05 0.26 0.94 62.84
129 INT329120 Binding of KCNA1 and CNTNAP2 1 0.09 1.23 0.75 61.96
130 INT300164 Npas2 Positive_regulation of Transcription of Per1 1 0.13 0.23 0 61.84
131 INT288263 Binding of AFA and MTRF1 1 0.02 1.28 0.49 60.44
132 INT199667 Cep290 Regulation of Atf4 1 0.04 1.96 0.09 60.16
133 INT316111 APC Negative_regulation of SAE1 1 0.04 1.21 0.22 59.76
134 INT328299 Binding of GHRH and GHS 1 0.07 2.21 0.31 59.64
135 INT199666 Cntln Regulation of Atf4 1 0.00 1.95 0.09 59.44
136 INT223036 SLURP1 Regulation of Positive_regulation of ADCY1 1 0.00 0.42 0.25 58.88
137 INT172513 ECT Negative_regulation of Mir343 1 0.02 0.24 0.47 58.24
138 INT306018 Binding of Tlr4 and Tlr9 1 0.15 0.92 0.27 57.92
139 INT306020 Binding of LBP and Tlr4 1 0.13 0.34 0.66 57.40
140 INT266102 Binding of PITX2 and RS1 1 0.00 0.64 0.8 57.32
141 INT160225 Acot1 Negative_regulation of Ache 1 0.28 2.18 0.25 56.12
142 INT160226 Acot1 Negative_regulation of Ache Positive_regulation of Acot1 1 0.23 1.18 0.13 56.12
143 INT65677 Binding of CGA and FSHR 2 0.25 0.29 0.16 54.88
144 INT223158 Mapk3 Regulation of Gene_expression of Mapk14 1 0.48 1.33 0.59 53.12
145 INT39109 Binding of INSRR and PDYN 1 0.15 0.45 1.46 52.80
146 INT39108 Binding of PDYN and YY1 2 0.50 0.44 2.14 52.08
147 INT337072 Binding of Fmr1 and Gusb 1 0.19 1.55 0.08 51.92
148 INT257466 Psd Negative_regulation of Gene_expression of Adipoq 1 0.22 0.66 0.08 51.92
149 INT210982 Binding of Cnr1 and Cfp 2 0.22 1.27 1.2 51.84
150 INT328896 Scn2a1 Regulation of hb 1 0.02 0.27 0.23 51.44
151 INT267812 Binding of ATF7IP and RLS 1 0.35 2.01 0.21 50.00
152 INT85358 Gm2078 Regulation of Prl 1 0.00 0 0 50.00
153 INT336561 Binding of DDC and DIO2 1 0.04 0.27 0.24 49.44
154 INT236365 Binding of CD40LG and IL6 3 0.20 4.16 1.42 48.96
155 INT143747 Binding of IL6 and LEP 2 0.04 4.05 0.38 48.96
156 INT327814 Rab8a Regulation of Regulation of Lep 1 0.01 0.15 0.19 47.88
157 INT327813 Rab8a Regulation of Lep 1 0.01 0.15 0.19 47.88
158 INT332773 Positive_regulation of Prkaca Positive_regulation of Phosphorylation of Grin1 1 0.04 0.73 1.75 46.92
159 INT250632 Binding of MCPH1 and Fbxo23 1 0.01 0 0.11 46.64
160 INT261845 NGF Positive_regulation of Trpa1 1 0.04 0.73 0.71 44.16
161 INT327809 Binding of ADORA2B and IL8 1 0.03 0.3 0 44.16
162 INT190986 Per1 Positive_regulation of Scn2a1 1 0.17 0 0.74 43.52
163 INT190979 Per2 Positive_regulation of Scn2a1 1 0.20 0 0.74 43.52
164 INT243276 Hrh4 Positive_regulation of Hrh3 1 0.25 0.78 0.52 43.36
165 INT172511 Mir343 Positive_regulation of ECT 1 0.04 0.08 0.6 43.32
166 INT251665 LRP5 Negative_regulation of Ache 1 0.31 0.39 0.19 42.32
167 INT179234 Binding of SERPINA6 and ELANE 1 0.01 0.22 0.12 42.32
168 INT279284 TXK Regulation of KDR 3 0.05 2.22 0.04 41.44
169 INT232787 CYBB Positive_regulation of Positive_regulation of Hif1a 1 0.01 0.66 0.12 40.96
170 INT220290 Binding of AFM and MARS 1 0.05 1.09 0.07 40.84
171 INT261831 Mapk1 Negative_regulation of Hspg2 1 0.00 1.26 1.42 39.00
172 INT348129 Bgn Regulation of Regulation of Hspg2 1 0.00 0.69 0.69 38.48
173 INT340295 Nrf1 Regulation of Ppargc1a 1 0.25 0 0.24 38.24
174 INT202969 Positive_regulation of SGSM3 Positive_regulation of MCRS1 1 0.02 1.22 0.47 37.72
175 INT281154 ITIH4 Positive_regulation of Cxcr4 1 0.09 0.71 0.37 37.40
176 INT281128 Cd4 Positive_regulation of Cxcr4 1 0.25 0.71 0.37 37.40
177 INT202964 SGSM3 Positive_regulation of MCRS1 1 0.03 1.21 0.47 37.28
178 INT350019 Regulation of Binding of Tnf and ARID1B 1 0.04 1.34 0.1 35.08
179 INT293014 IRF6 Positive_regulation of Localization of CA2 1 0.04 0.71 1.02 32.80
180 INT293008 IL8 Positive_regulation of Localization of CA2 1 0.11 0.71 1.01 32.48
181 INT223155 Binding of Mapk14 and Stat4 1 0.36 0.84 0.63 32.40
182 INT267686 Binding of RYBP and CENPJ 1 0.01 0.12 0.03 29.68
183 INT223154 Negative_regulation of Mapk14 Negative_regulation of Localization of Il6 1 0.19 1.13 1.11 28.40
184 INT261832 Trpv1 Negative_regulation of Trpa1 1 0.10 0.58 0.64 27.56
185 INT261830 Hspg2 Negative_regulation of Trpa1 1 0.01 0.58 0.63 27.28
186 INT223157 Abat Negative_regulation of Localization of Il6 1 0.05 1.13 1.1 26.96
187 INT200063 Binding of MAGED1 and Ngfr 1 0.44 0.45 0 26.64
188 INT200055 Binding of Ngfr and Mageh1 1 0.33 0.45 0 26.64
189 INT350012 Binding of TNF and ARID1B 1 0.01 2.25 0.12 26.24
190 INT262335 Binding of Sv2a and Bri3 1 0.01 0.71 0.08 26.12
191 INT200065 Binding of MAGED1 and Ntf3 1 0.32 0.23 0 26.08
192 INT200054 Binding of Ntf3 and Mageh1 1 0.24 0.22 0 26.08
193 INT142437 Urb1 Negative_regulation of Faah 3 0.41 2.12 1.66 25.00
194 INT129869 SERPINA6 Regulation of AVP 1 0.25 2.33 0.54 25.00
195 INT105771 CRH Negative_regulation of Localization of GNRH1 1 0.35 0.56 0.39 25.00
196 INT105772 SST Negative_regulation of Localization of GH1 1 0.10 0.54 0.38 25.00
197 INT105770 SST Negative_regulation of Localization of TRH 1 0.17 0.54 0.38 25.00
198 INT134324 Gh Regulation of Gene_expression of F8a 1 0.07 0 0.33 25.00
199 INT129868 Regulation of SERPINA6 Regulation of AVP 1 0.25 0.59 0.14 25.00
200 INT158141 Binding of HOXD13 and SNCA 1 0.54 0.41 0.11 25.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Sleep Disorders. They are ordered first by their pain relevance and then by number of times they were reported in Sleep Disorders. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT185415 Negative_regulation of ZNF717 1 0.02 15.19 1.67 100.00
2 INT75742 Binding of RLS 86 0.42 95.27 19.04 100.00
3 INT235591 Positive_regulation of ITSN2 1 0.49 5.77 0 100.00
4 INT88867 Localization of MCS 19 0.62 28.31 3.88 100.00
5 INT235589 Negative_regulation of ITSN2 1 0.41 4.84 0 100.00
6 INT54924 Gene_expression of RLS 67 0.62 83.2 14.25 100.00
7 INT85963 Gene_expression of LIFR 23 0.75 9 0.98 100.00
8 INT155 Positive_regulation of Prl 1233 0.70 317.93 457.82 100.00
9 INT16259 Positive_regulation of Bdnf 336 0.70 183.48 209.82 100.00
10 INT3448 Positive_regulation of Gh 521 0.69 180.03 161.18 100.00
11 INT1497 Negative_regulation of Gh 415 0.59 192.95 74.71 100.00
12 INT81154 Gene_expression of HCRT 10 0.75 5.32 2.22 100.00
13 INT178458 Negative_regulation of LIFR 13 0.47 8.75 2.48 100.00
14 INT47127 Gene_expression of BGN 11 0.75 17.09 6.25 100.00
15 INT1682 Negative_regulation of Rem1 28 0.37 7.38 8.4 100.00
16 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 100.00
17 INT154104 Binding of ARID1B 47 0.39 69.82 1.49 100.00
18 INT438 Gene_expression of Crh 376 0.78 159.11 169.17 100.00
19 INT142735 Regulation of RLS 33 0.53 45.83 11.35 100.00
20 INT11685 Regulation of CSF2 99 0.59 58.82 15.9 100.00
21 INT300166 Negative_regulation of FBXL15 1 0.03 4.07 0.41 100.00
22 INT30294 Gene_expression of IGKV1D-39 30 0.62 8.66 5.26 100.00
23 INT46273 Gene_expression of PRNP 103 0.78 110.34 9.25 100.00
24 INT321985 Gene_expression of Etan1 1 0.01 1.5 0.28 100.00
25 INT202176 Gene_expression of MIXL1 4 0.65 1.5 0.29 100.00
26 INT56084 Negative_regulation of SLC43A3 11 0.39 5.39 2.27 100.00
27 INT45303 Binding of SYNM 4 0.40 2.14 3.07 100.00
28 INT2211 Negative_regulation of Abat 267 0.59 66.51 200.98 100.00
29 INT28728 Regulation of Cfp 49 0.46 13.15 21.43 100.00
30 INT34624 Negative_regulation of REM1 22 0.38 9.25 4.22 100.00
31 INT23402 Binding of HLA-DOA 74 0.48 52.01 10.89 100.00
32 INT259697 Regulation of MSSE 6 0.14 3 0.23 100.00
33 INT169180 Binding of SNRNP70 204 0.47 119.1 29.3 100.00
34 INT100601 Localization of PRNP 17 0.66 13.61 0.71 100.00
35 INT73413 Negative_regulation of SRPX 3 0.05 1.1 0.52 100.00
36 INT125242 Localization of RLS 15 0.64 15.87 4.99 100.00
37 INT1309 Positive_regulation of Localization of Gnrhr 152 0.69 24.25 81.56 100.00
38 INT5513 Negative_regulation of Pomc 295 0.59 60.9 158.63 100.00
39 INT171145 Positive_regulation of Fig4 274 0.59 93.55 69.81 100.00
40 INT296875 Positive_regulation of AHI1 2 0.15 3.53 0.16 100.00
41 INT185412 Negative_regulation of CFD 5 0.27 3.49 0.2 100.00
42 INT185413 Positive_regulation of ZNF717 1 0.02 0.77 0.06 100.00
43 INT222723 Negative_regulation of Localization of PRNP 1 0.05 2.06 0 100.00
44 INT14690 Localization of CSF2 124 0.80 85.17 27.26 100.00
45 INT300167 Binding of FBXL15 2 0.39 5 0.19 100.00
46 INT162 Regulation of Prl 794 0.62 165.01 322.24 100.00
47 INT235590 Negative_regulation of Binding of ITSN2 1 0.30 0.65 0 100.00
48 INT118912 Regulation of Positive_regulation of cerebral blood flow 1 0.01 0.82 0.23 100.00
49 INT161766 Localization of Psd 7 0.75 3.53 0.96 100.00
50 INT16253 Positive_regulation of Gene_expression of Bdnf 196 0.70 92.67 113.01 100.00
51 INT191766 Negative_regulation of Gene_expression of IGKV1D-39 8 0.07 3.4 1.14 100.00
52 INT229603 Negative_regulation of Localization of RLS 2 0.36 2.62 0.32 100.00
53 INT233130 Regulation of PKN1 2 0.02 0.69 0.18 100.00
54 INT10228 Positive_regulation of PCS 49 0.67 28.72 7 100.00
55 INT27346 Regulation of ANIB1 5 0.03 3.47 1.47 100.00
56 INT73802 Regulation of Selp 17 0.60 8.72 3.51 100.00
57 INT229604 Regulation of Localization of RLS 1 0.38 1.17 0 100.00
58 INT254139 Negative_regulation of Localization of SLC43A3 1 0.02 0.73 0 100.00
59 INT254138 Localization of SLC43A3 1 0.04 0.73 0 100.00
60 INT122561 Negative_regulation of Gene_expression of Adipoq 12 0.56 14.02 2.26 100.00
61 INT149762 Regulation of MAS1 8 0.31 5.34 1.61 100.00
62 INT178455 Localization of LIFR 6 0.61 2.24 0.83 100.00
63 INT151927 Regulation of Gene_expression of Adipoq 3 0.43 3.32 0.81 100.00
64 INT58258 Regulation of sea 5 0.39 0.63 0.6 100.00
65 INT20672 Gene_expression of CDS1 19 0.76 8.19 4.08 100.00
66 INT145937 Regulation of PCS 32 0.39 19.25 1.97 100.00
67 INT274053 Gene_expression of FBXL15 2 0.65 1.56 0.03 100.00
68 INT3776 Positive_regulation of Regulation of NARFL 2 0.37 2.44 0.93 100.00
69 INT73412 Negative_regulation of ZIC3 2 0.20 0.72 0.46 100.00
70 INT8528 Negative_regulation of Gene_expression of Fos 100 0.59 41.15 55.6 100.00
71 INT1652 Regulation of Pomc 387 0.62 61.01 186.51 100.00
72 INT193399 Localization of SEA 4 0.54 0.6 0.2 100.00
73 INT290793 Negative_regulation of Clock 6 0.39 1.48 0.09 100.00
74 INT138216 Negative_regulation of PER1 13 0.37 9.66 4.55 100.00
75 INT256898 Negative_regulation of Localization of RSS 1 0.07 0.32 0 100.00
76 INT7867 Regulation of Negative_regulation of Gh 5 0.33 1.92 0.87 100.00
77 INT770 Regulation of Localization of Gnrhr 127 0.61 17.91 58.23 100.00
78 INT56651 Binding of HLA-DRB1 58 0.48 52.25 13.68 100.00
79 INT70176 Negative_regulation of Sd 1 0.05 0.28 0.21 100.00
80 INT92321 Regulation of Impact 3 0.23 1.15 0.65 100.00
81 INT235585 Negative_regulation of Negative_regulation of LIFR 1 0.16 0.35 0 100.00
82 INT235588 Negative_regulation of Negative_regulation of ITSN2 1 0.30 0.35 0 100.00
83 INT117499 Negative_regulation of Adipoq 28 0.56 24.15 5.07 100.00
84 INT161919 Gene_expression of Mir873 1 0.58 0.57 0.42 100.00
85 INT58770 Gene_expression of MSSE 9 0.56 5.75 0.08 100.00
86 INT167203 Binding of PRNP 25 0.48 20.09 1.84 100.00
87 INT34263 Positive_regulation of Mastl 8 0.35 1.36 4.35 100.00
88 INT1976 Regulation of Gene_expression of Prl 80 0.62 20.19 36 100.00
89 INT31456 Positive_regulation of Negative_regulation of Rem1 1 0.08 0.3 0.48 100.00
90 INT345953 Negative_regulation of Ahi1 1 0.08 4.67 0 100.00
91 INT2274 Regulation of Localization of INS 101 0.62 41.55 34.79 100.00
92 INT85233 Localization of SGSM3 11 0.78 10.91 3.41 100.00
93 INT59302 Positive_regulation of POR 19 0.49 15.18 1.95 100.00
94 INT71762 Negative_regulation of sea 6 0.36 1.73 1.86 100.00
95 INT163592 Localization of CISH 5 0.54 5.9 1.26 100.00
96 INT110163 Binding of HLA-DQB1 8 0.25 4.71 0.98 100.00
97 INT42319 Gene_expression of Hpd 5 0.44 11.25 0.9 100.00
98 INT42321 Regulation of Gene_expression of Hpd 1 0.20 0.1 0.54 100.00
99 INT243283 Negative_regulation of AIRN 3 0.37 1 0.04 100.00
100 INT305764 Regulation of Negative_regulation of AIRN 1 0.14 0.35 0 100.00
101 INT2531 Positive_regulation of Cebpz 166 0.00 43.08 38.86 99.98
102 INT7608 Positive_regulation of Adra2a 66 0.70 17.81 35.15 99.98
103 INT35261 Positive_regulation of Positive_regulation of Cebpz 13 0.41 2.52 3.87 99.98
104 INT2339 Positive_regulation of CB 30 0.29 10.68 9.12 99.98
105 INT193504 Positive_regulation of OPN1SW 11 0.58 7.44 1.47 99.98
106 INT5690 Negative_regulation of Binding of Oprd1 36 0.59 8.29 24.52 99.98
107 INT5128 Positive_regulation of Lhb 232 0.69 44.23 71.26 99.98
108 INT11439 Positive_regulation of Csf2 105 0.69 62.63 37.77 99.98
109 INT106057 Negative_regulation of Hcrt 27 0.57 15.5 3.47 99.96
110 INT1351 Gene_expression of Pag1 131 0.57 89.48 98.76 99.96
111 INT28166 Positive_regulation of Rem1 8 0.40 7.96 3.19 99.96
112 INT767 Localization of Gnrhr 565 0.80 106.68 214.57 99.96
113 INT62773 Gene_expression of RSS 9 0.65 4.44 0.62 99.96
114 INT117849 Negative_regulation of Gene_expression of IGFBP3 8 0.39 8.75 0.75 99.96
115 INT43984 Regulation of Gene_expression of LPA 7 0.49 6.3 0.61 99.96
116 INT1614 Gene_expression of Oprl1 164 0.78 31.43 127.74 99.96
117 INT118676 Positive_regulation of Camk4 34 0.70 16.67 10.9 99.96
118 INT100275 Gene_expression of TBL1XR1 19 0.25 6.99 1.33 99.96
119 INT100277 Positive_regulation of Gene_expression of TBL1XR1 5 0.19 1.9 0.25 99.96
120 INT347922 Negative_regulation of Scpro1 1 0.00 2.75 0.1 99.92
121 INT9649 Positive_regulation of LPA 105 0.69 74.75 13.89 99.92
122 INT117500 Gene_expression of Adipoq 90 0.74 67.79 16.58 99.92
123 INT229894 Localization of COQ10A 8 0.69 2.95 0.79 99.92
124 INT147583 Gene_expression of AIS 82 0.58 48.7 7.11 99.92
125 INT19155 Binding of Adora1 25 0.47 6.41 10.72 99.92
126 INT101699 Regulation of Adora1 14 0.61 3.7 7.59 99.92
127 INT189249 Localization of BGN 2 0.08 2.14 0.8 99.92
128 INT135374 Binding of Gsk3b 46 0.48 24.36 4.75 99.92
129 INT2836 Positive_regulation of PAEP 51 0.67 26.69 4.57 99.92
130 INT128555 Positive_regulation of HIST1H1B 5 0.24 1.49 0.07 99.92
131 INT1138 Positive_regulation of IgG-2a 16 0.68 5.59 8.11 99.92
132 INT164151 Gene_expression of Pvrl2 1 0.06 1.29 0.2 99.92
133 INT2651 Positive_regulation of Pomc 403 0.70 95.72 206.24 99.90
134 INT103463 Localization of CPP 16 0.66 9.63 4.08 99.90
135 INT106169 Localization of RHOJ 3 0.78 1.73 0.56 99.90
136 INT126685 Gene_expression of Rem1 30 0.65 11.21 3.61 99.88
137 INT1169 Negative_regulation of Bche 322 0.59 149.22 61.27 99.88
138 INT157 Positive_regulation of Localization of Prl 790 0.70 104.54 374.78 99.88
139 INT138307 Regulation of Tcm 15 0.39 4.1 0.81 99.88
140 INT3466 Gene_expression of Ptger1 39 0.75 18.34 15.75 99.86
141 INT69440 Gene_expression of ROS1 752 0.78 477.64 103.83 99.84
142 INT24989 Positive_regulation of Cfp 125 0.61 29.55 64.9 99.84
143 INT148886 Negative_regulation of Gene_expression of HCRTR1 2 0.23 3.42 0.05 99.84
144 INT99281 Negative_regulation of HCRT 3 0.57 2.26 0.71 99.84
145 INT69441 Regulation of Gene_expression of ROS1 38 0.50 26.78 6.78 99.84
146 INT16260 Gene_expression of Bdnf 671 0.78 283.44 339.1 99.84
147 INT287248 Positive_regulation of Positive_regulation of Cfp 1 0.19 0.76 0.04 99.84
148 INT56749 Gene_expression of PCNA 219 0.77 111.25 18.42 99.84
149 INT50558 Negative_regulation of PCNA 31 0.57 13.97 2.3 99.84
150 INT11708 Regulation of SCT 12 0.44 2.29 4.07 99.84
151 INT287254 Positive_regulation of Negative_regulation of PKN1 1 0.01 0.41 0 99.84
152 INT130105 Positive_regulation of HCRTR1 3 0.27 6.47 0.38 99.82
153 INT91217 Positive_regulation of BAG3 22 0.48 16.57 6.06 99.82
154 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 99.82
155 INT347919 Positive_regulation of Negative_regulation of Scpro1 1 0.01 0.82 0.07 99.82
156 INT78669 Negative_regulation of CYP2C18 2 0.33 1.45 0.79 99.82
157 INT5497 Positive_regulation of Crh 299 0.70 125.54 131.14 99.80
158 INT316079 Negative_regulation of Vapa 1 0.03 6.88 0.41 99.80
159 INT182658 Regulation of Gene_expression of Rem1 4 0.20 2.55 0.47 99.80
160 INT5016 Negative_regulation of Crh 129 0.59 36.74 59.28 99.80
161 INT16879 Binding of Crh 72 0.48 21.65 28.43 99.80
162 INT22557 Gene_expression of BMP1 3 0.59 20.18 4.73 99.80
163 INT21671 Regulation of CHSY3 1 0.11 2.27 2.47 99.80
164 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 99.80
165 INT235583 Localization of Rem1 1 0.10 0.77 0 99.80
166 INT147792 Gene_expression of COPD 230 0.70 287.13 24.1 99.80
167 INT27627 Binding of Rac1 41 0.41 22.88 13.68 99.80
168 INT71515 Negative_regulation of CHPT1 6 0.38 2.28 1.51 99.80
169 INT126503 Negative_regulation of ipv 5 0.46 4.32 0.53 99.80
170 INT106056 Gene_expression of Hcrt 77 0.76 35.35 8.16 99.78
171 INT11587 Gene_expression of CSF2 645 0.78 544.38 93.89 99.78
172 INT528 Gene_expression of Prl 693 0.78 217.18 192.2 99.78
173 INT2213 Regulation of EP300 10 0.54 4.72 4.5 99.78
174 INT122896 Negative_regulation of TH 23 0.57 9.27 6.88 99.78
175 INT2924 Positive_regulation of sch 11 0.50 4.09 3.82 99.78
176 INT19330 Binding of HLA-A 99 0.48 76.26 22.85 99.76
177 INT10116 Localization of INSR 11 0.57 5.43 3.48 99.76
178 INT208004 Localization of RSS 2 0.12 1.62 0.53 99.76
179 INT6105 Positive_regulation of IL2 133 0.69 82.76 34.67 99.76
180 INT152796 Protein_catabolism of RLS 4 0.59 3.64 0.33 99.76
181 INT185519 Binding of Vms1 5 0.12 4.58 1.37 99.76
182 INT80779 Positive_regulation of Hbb-ar 10 0.41 2.48 3.29 99.76
183 INT130556 Binding of CACNA1C 3 0.22 1.84 0.4 99.76
184 INT3758 Gene_expression of ALB 326 0.78 184.65 38.75 99.74
185 INT216873 Binding of TBL1XR1 3 0.36 4.44 0.4 99.74
186 INT287251 Negative_regulation of PKN1 6 0.01 1.86 0.25 99.72
187 INT45365 Negative_regulation of Cfp 68 0.57 25.44 32.11 99.72
188 INT235586 Binding of ITSN2 1 0.26 1.22 0 99.72
189 INT41878 Positive_regulation of EP300 13 0.61 5.24 3.95 99.72
190 INT53194 Negative_regulation of Positive_regulation of Cfp 10 0.45 4.87 4.78 99.72
191 INT211228 Localization of Serpind1 3 0.63 6.11 0.51 99.72
192 INT235592 Positive_regulation of Binding of ITSN2 1 0.35 0.65 0 99.72
193 INT44249 Negative_regulation of ELK3 8 0.51 1.99 4.45 99.72
194 INT14031 Gene_expression of Npy 107 0.78 36.48 35.4 99.72
195 INT152668 Negative_regulation of EP300 13 0.38 7.78 9.03 99.72
196 INT15189 Localization of Npy 26 0.79 9.09 8.28 99.72
197 INT929 Positive_regulation of Oprl1 64 0.70 14.67 52.84 99.72
198 INT796 Gene_expression of Penk 1902 0.78 275.47 1057.59 99.72
199 INT2783 Gene_expression of Slc3a1 86 0.65 8.84 45.4 99.72
200 INT25864 Gene_expression of Nme4 4 0.40 0.46 2.47 99.72
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