D:Small Cell Lung Cancer

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Disease Term
Synonyms Carcinoma Oat Cell, Carcinoma Reserve Cell, Carcinoma Round Cell, Carcinoma Small Cell, Carcinoma Small Cell Lung, Carcinomas Oat Cell, CARCINOMAS RESERVE CELL, Carcinomas Round Cell, CARCINOMAS SMALL CELL, OAT CELL, OAT CELL CARCINOMA
Documents 424
Hot Single Events 200
Hot Interactions 21

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Small Cell Lung Cancer. They are ordered first by their relevance to Small Cell Lung Cancer and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT280830 Binding of Avp and Usf2 1 0.02 0.53 0 100.00
2 INT280851 Binding of Avp and Usf2 Positive_regulation of Gene_expression of Avp 1 0.00 0.53 0 100.00
3 INT280829 Binding of Tcf12 and Usf2 1 0.00 0.53 0 100.00
4 INT280844 Binding of Avp and Tcf12 1 0.00 0.52 0 99.70
5 INT280835 Usf1 Positive_regulation of Gene_expression of Avp 1 0.03 1.06 0 99.68
6 INT280812 Usf2 Positive_regulation of Gene_expression of Avp 1 0.03 0.52 0 99.68
7 INT306830 E2F2 Regulation of C1orf61 1 0.02 0.48 0.36 99.20
8 INT72817 Agt Negative_regulation of Avp 1 0.07 0.34 0.14 98.52
9 INT72818 Edn3 Negative_regulation of Avp 1 0.08 0.34 0.14 98.52
10 INT306824 Binding of E2F1 and E2F2 1 0.15 0.15 0.46 96.88
11 INT306828 Binding of E2F2 and E2F3 1 0.20 0.15 0.46 96.28
12 INT214437 NCAM1 Regulation of CHGA 1 0.05 1.21 0.07 94.32
13 INT306822 Binding of E2F2 and GOPC 1 0.05 0.53 0.35 93.80
14 INT72819 Regulation of EDN3 Positive_regulation of Avp 1 0.28 0.32 0.13 91.92
15 INT280848 Binding of REST and Rest 1 0.02 0.09 0 91.92
16 INT280837 Binding of Rest and Negative_regulation of Gene_expression of Avp 1 0.00 0.09 0 91.92
17 INT72820 EDN3 Positive_regulation of Avp 1 0.31 0.64 0.27 91.36
18 INT306823 Binding of E2F4 and GOPC 1 0.06 0.23 0.91 90.04
19 INT244116 ELAVL3 Negative_regulation of MUC1 1 0.09 3.41 0.15 88.72
20 INT280849 REST Negative_regulation of Gene_expression of Avp 1 0.09 0.09 0 86.88
21 INT280815 Vmn1r66 Negative_regulation of Gene_expression of Avp 1 0.00 0.09 0 86.88
22 INT189956 TP53 Positive_regulation of Gene_expression of Pttg1 1 0.06 1.21 0 77.80
23 INT306831 Positive_regulation of Binding of E2F4 and NOLC1 1 0.10 0.46 0.85 75.00
24 INT306826 Binding of E2F4 and NOLC1 1 0.08 0.41 0.84 75.00
25 INT263899 Binding of PTPRC and TMED7-TICAM2 1 0.00 0.85 0 68.40
26 INT210288 Binding of CD8A and ELAVL4 1 0.27 1.21 0.07 57.44
27 INT306829 Binding of E2F2 and RBL1 1 0.09 0.06 0 55.36
28 INT258521 EGFR Positive_regulation of MMP2 1 0.39 0.91 0.24 55.00
29 INT258565 EGFR Positive_regulation of Meta 1 0.39 0.89 0.23 55.00
30 INT306827 Binding of E2F2 and NOLC1 1 0.07 0.05 0 54.64
31 INT291329 Binding of NOTCH1 and CERS1 1 0.06 1.42 0 54.24
32 INT306825 Positive_regulation of Binding of E2F2 and RB1 1 0.04 0.05 0 54.16
33 INT238393 Binding of E2F2 and RB1 3 0.04 0.24 0 54.16
34 INT175398 Binding of ERBB2 and VEGFA 2 0.16 1.34 0.13 53.76
35 INT175401 Binding of EGFR and VEGFA 2 0.13 1.49 0.13 53.12
36 INT291330 Binding of ENO1 and NOTCH1 1 0.03 1.33 0 51.52
37 INT291333 Binding of CSHL1 and NOTCH1 1 0.05 1.16 0 49.20
38 INT275232 DUOX2 Positive_regulation of ROS1 1 0.10 0.33 0 41.76
39 INT258529 Binding of JAG1 and NOTCH1 3 0.06 2.44 0 31.44
40 INT258528 Binding of NOTCH1 and DLL1 2 0.07 1.6 0 30.72
41 INT210286 Binding of ELAVL4 and GOPC 1 0.06 0.87 0 28.16
42 INT210287 Binding of CD8A and GOPC 1 0.07 0.87 0 28.16
43 INT258564 Binding of NOTCH1 and Crlf2 1 0.27 0.67 0 24.24
44 INT268678 Binding of HDAC2 and NCOR2 1 0.18 2.67 0.07 21.92
45 INT268679 Binding of HDAC1 and NCOR2 3 0.17 2.8 0.07 21.12
46 INT268676 Binding of HDAC1 and BCOR 1 0.01 1.31 0.04 21.12
47 INT268675 Binding of NCOR2 and SIN3A 1 0.27 2.54 0.07 18.48
48 INT268673 Binding of NCOR2 and BCOR 1 0.01 2.54 0.07 16.88
49 INT258526 IPMK Negative_regulation of BRAF 1 0.01 1.11 0 16.48
50 INT258524 IPMK Negative_regulation of KDR 2 0.00 1.98 0 15.68
51 INT258525 IPMK Negative_regulation of DDR1 2 0.00 1.97 0 15.12
52 INT60626 Crh Positive_regulation of Localization of Pomc 7 0.54 2.3 1.99 5.00
53 INT213071 IL6 Positive_regulation of Gene_expression of CRP 4 0.52 6.58 1.68 5.00
54 INT226337 Binding of IL10 and IL10RA 2 0.24 2.51 0.85 5.00
55 INT122191 Binding of Crh and Ucn 4 0.36 0.79 0.82 5.00
56 INT122190 Binding of Crhr1 and Ucn 4 0.49 0.65 0.67 5.00
57 INT93063 Binding of gr and Jun 3 0.14 0.79 0.57 5.00
58 INT149473 Avp Positive_regulation of Localization of Pomc 4 0.48 2.64 0.56 5.00
59 INT280826 Il6 Positive_regulation of Localization of Avp 1 0.01 0.64 0.47 5.00
60 INT263917 Binding of SST and Sstr5 2 0.02 0.56 0.45 5.00
61 INT122188 Binding of Crh and Ucn2 2 0.22 0.29 0.38 5.00
62 INT122189 Binding of Crhr1 and Ucn2 2 0.08 0.27 0.36 5.00
63 INT287380 Binding of VEGFA and Kdr 12 0.18 11.97 0.34 5.00
64 INT280808 Prkcg Positive_regulation of Transcription of Fos 1 0.02 0.06 0.33 5.00
65 INT280838 Binding of Crh and gr 1 0.06 0 0.33 5.00
66 INT280814 Positive_regulation of Mapk1 Positive_regulation of Transcription of Fos 1 0.02 0.06 0.33 5.00
67 INT101810 Binding of NFE2L2 and KEAP1 7 0.53 4.12 0.29 5.00
68 INT280827 Positive_regulation of Fos Positive_regulation of Avp 1 0.02 0.08 0.28 5.00
69 INT101813 KEAP1 Negative_regulation of NFE2L2 3 0.47 1.63 0.28 5.00
70 INT280825 Mapk1 Positive_regulation of Avp 1 0.01 0.08 0.28 5.00
71 INT280807 Mapk1 Positive_regulation of Positive_regulation of Prkcg 1 0.01 0.08 0.28 5.00
72 INT280832 Binding of Crh and Ucn3 1 0.16 0.07 0.27 5.00
73 INT280850 Binding of Crh and Ucn Positive_regulation of Negative_regulation of Crh 1 0.26 0.06 0.27 5.00
74 INT280822 Jun Regulation of Regulation of Crh 1 0.20 0.08 0.27 5.00
75 INT280805 Positive_regulation of Prkcg Positive_regulation of Avp 1 0.01 0.16 0.26 5.00
76 INT280811 Binding of Crhr1 and Ucn3 1 0.08 0.05 0.25 5.00
77 INT354926 IL6 Regulation of Gene_expression of ALB 1 0.14 1.3 0.23 5.00
78 INT354924 IL6 Positive_regulation of Gene_expression of ALB 1 0.26 1.3 0.23 5.00
79 INT121050 Crh Regulation of Localization of Pomc 4 0.43 0.6 0.22 5.00
80 INT280820 S100a8 Positive_regulation of Gene_expression of Crh 1 0.01 0.65 0.19 5.00
81 INT280839 Il6 Positive_regulation of Gene_expression of Crh 1 0.09 0.1 0.19 5.00
82 INT280833 Il1 Positive_regulation of Gene_expression of Crh 1 0.05 0.09 0.17 5.00
83 INT280846 Crh Positive_regulation of Localization of POMC 1 0.03 0.37 0.16 5.00
84 INT263901 Binding of Ighg1 and Slc3a2 1 0.00 0.89 0.16 5.00
85 INT280813 Binding of Avp and S100a8 1 0.00 0.28 0.15 5.00
86 INT263081 IFN1@ Regulation of CXCL10 1 0.07 0.15 0.15 5.00
87 INT328851 Binding of PTGS2 and ZNF434 1 0.00 0.7 0.14 5.00
88 INT280819 Binding of Creb1 and gr 1 0.01 0 0.13 5.00
89 INT280809 Binding of gr and Rela 1 0.00 0 0.13 5.00
90 INT258527 Binding of BRAF and RET 1 0.21 1.49 0.11 5.00
91 INT199583 HIF1A Positive_regulation of Gene_expression of Vhl 1 0.26 1.39 0.11 5.00
92 INT243468 Binding of SSTR1 and SSTR5 1 0.05 0.99 0.1 5.00
93 INT280836 Gene_expression of Fos Positive_regulation of Crh 1 0.09 0.17 0.1 5.00
94 INT258522 Binding of DDR1 and RET 1 0.03 1.05 0.1 5.00
95 INT280841 Jun Positive_regulation of Gene_expression of Crh 1 0.35 0.16 0.1 5.00
96 INT243465 Binding of GH1 and GOPC 1 0.02 0.99 0.09 5.00
97 INT244452 CS Positive_regulation of Phosphorylation of EIF2S2 1 0.21 2.07 0.09 5.00
98 INT354925 ALB Positive_regulation of ALPP 1 0.34 1.69 0.09 5.00
99 INT243466 POU1F1 Regulation of GH1 1 0.11 1.26 0.08 5.00
100 INT243464 POU1F1 Regulation of PRL 1 0.28 1.26 0.08 5.00
101 INT280821 Son Regulation of Gene_expression of gr 1 0.01 0.18 0.08 5.00
102 INT189957 Binding of LDHA and Pttg1 1 0.05 0.35 0.08 5.00
103 INT244449 CS Regulation of Gene_expression of ATF4 1 0.15 0.83 0.08 5.00
104 INT232917 Binding of KRT8 and KRT19 2 0.16 1.04 0.08 5.00
105 INT280810 Avp Negative_regulation of Gene_expression of Pomc 1 0.02 0.22 0.06 5.00
106 INT280816 Crh Positive_regulation of Gene_expression of Pomc 1 0.15 0.28 0.06 5.00
107 INT280818 Jun Positive_regulation of Avp 1 0.06 0.23 0.06 5.00
108 INT280834 Negative_regulation of Jun Positive_regulation of Avp 1 0.05 0.23 0.06 5.00
109 INT197553 Binding of NFE2L2 and LILRA3 1 0.03 0.43 0.06 5.00
110 INT232914 Binding of KRT2 and KRT7 1 0.15 0.63 0.05 5.00
111 INT268677 IFNA2 Positive_regulation of XRCC1 1 0.05 0.75 0.05 5.00
112 INT232916 Binding of KRT2 and KRT19 1 0.21 0.62 0.05 5.00
113 INT232907 Binding of KRT7 and KRT8 1 0.09 0.63 0.05 5.00
114 INT244461 CS Positive_regulation of ESR1 1 0.06 1.15 0.05 5.00
115 INT233855 Binding of Ppara and Mapk7 1 0.09 0.9 0.05 5.00
116 INT221815 PPARA Negative_regulation of PTEN 1 0.15 0.5 0.05 5.00
117 INT268674 IL2 Positive_regulation of XRCC1 1 0.08 0.75 0.05 5.00
118 INT280843 Binding of Crem and Crh 1 0.03 0.22 0.04 5.00
119 INT233850 Zeb1 Positive_regulation of Itk 1 0.04 0.58 0.04 5.00
120 INT280817 Binding of Cdx1 and Crh 1 0.02 0.21 0.04 5.00
121 INT233849 Twist1 Positive_regulation of Snai2 1 0.07 0.58 0.04 5.00
122 INT244464 EIF2AK3 Positive_regulation of Positive_regulation of EIF2S2 1 0.17 0.37 0.04 5.00
123 INT244463 EIF2AK3 Regulation of Phosphorylation of EIF2S2 1 0.09 0.37 0.04 5.00
124 INT233848 Zeb1 Positive_regulation of Snai1 1 0.07 0.58 0.04 5.00
125 INT233853 Zeb1 Positive_regulation of Snai2 1 0.09 0.58 0.04 5.00
126 INT233852 Twist1 Positive_regulation of Snai1 1 0.02 0.58 0.04 5.00
127 INT233851 Twist1 Positive_regulation of Zeb1 1 0.06 0.58 0.04 5.00
128 INT197546 NFE2L2 Regulation of Gene_expression of ABCC2 1 0.17 0.72 0.04 5.00
129 INT233854 Twist1 Positive_regulation of Itk 1 0.03 0.58 0.04 5.00
130 INT280569 Binding of GEM and HIVEP1 1 0.00 1.59 0.03 5.00
131 INT280601 Binding of HIVEP1 and Dbi 1 0.00 1.57 0.03 5.00
132 INT244474 CS Regulation of XBP1 1 0.20 0.15 0 5.00
133 INT280823 Positive_regulation of Prkaca Positive_regulation of Gene_expression of Crh 1 0.08 0.11 0 5.00
134 INT232918 Binding of KRT2 and KRT8 1 0.17 0.59 0 5.00
135 INT280568 MRAS Positive_regulation of RAF1 1 0.01 0.7 0 5.00
136 INT268258 Binding of hb and Ugt1a10 1 0.00 1.18 0 5.00
137 INT244480 CS Negative_regulation of Gene_expression of XBP1 1 0.16 0.11 0 5.00
138 INT244462 XBP1 Regulation of Gene_expression of DNAJB11 1 0.11 0 0 5.00
139 INT199581 Braf Negative_regulation of Phosphorylation of tk 1 0.05 0.6 0 5.00
140 INT244454 Binding of EIF2AK3 and SIL1 1 0.05 0.41 0 5.00
141 INT263900 Binding of Col1a1 and Cea 1 0.01 0.63 0 5.00
142 INT244476 CS Positive_regulation of ATF3 1 0.13 0.13 0 5.00
143 INT244469 CS Positive_regulation of PPP1R15A 1 0.08 0.12 0 5.00
144 INT280566 Binding of ARAF and BCL2 1 0.02 0.69 0 5.00
145 INT244457 CS Positive_regulation of Gene_expression of ESR1 1 0.07 0.67 0 5.00
146 INT280840 Avp Regulation of Localization of Pomc 1 0.02 0.16 0 5.00
147 INT244458 CS Positive_regulation of ERN1 1 0.17 0.71 0 5.00
148 INT243467 PCSK1 Positive_regulation of POMC 1 0.08 1.62 0 5.00
149 INT244475 Binding of CS and Positive_regulation of EIF2S2 1 0.11 0.07 0 5.00
150 INT244473 ATF6 Regulation of Gene_expression of DNAJB11 1 0.10 0 0 5.00
151 INT321642 Binding of Cd3e and Spn 1 0.00 1.08 0 5.00
152 INT280845 Binding of ELANE and Avp 1 0.06 0 0 5.00
153 INT322413 Binding of ATF1 and EWSR1 1 0.26 1.3 0 5.00
154 INT244459 ERN1 Regulation of Positive_regulation of MAPK8 1 0.03 0.47 0 5.00
155 INT199576 Raf1 Negative_regulation of Akt1 1 0.00 0.79 0 5.00
156 INT291335 Positive_regulation of RAF1 Positive_regulation of Phosphorylation of GSK3A 1 0.07 0.88 0 5.00
157 INT244450 TMBIM6 Negative_regulation of Gene_expression of ESR1 1 0.04 0.68 0 5.00
158 INT197576 Loh1 Positive_regulation of NFE2L2 1 0.49 1.1 0 5.00
159 INT258523 Positive_regulation of RAF1 Positive_regulation of Phosphorylation of GSK 1 0.19 0.64 0 5.00
160 INT199580 Braf Negative_regulation of Phosphorylation of Mdk 1 0.11 0.6 0 5.00
161 INT280806 Avpr1b Positive_regulation of Localization of Pomc 1 0.19 0.17 0 5.00
162 INT232912 Binding of KRT4 and KRT13 1 0.07 0.06 0 5.00
163 INT232910 Binding of KRT12 and KRT76 1 0.39 0.2 0 5.00
164 INT185353 Eri1 Negative_regulation of Transcription of Egfr 1 0.01 0.5 0 5.00
165 INT197544 Binding of KEAP1 and KLHL2 1 0.02 0.43 0 5.00
166 INT240271 Binding of GDNF and RET 1 0.09 1.04 0 5.00
167 INT175400 RASGRP1 Positive_regulation of MAP3K5 1 0.00 1.2 0 5.00
168 INT199577 Tnk1 Negative_regulation of Akt1 1 0.00 0.79 0 5.00
169 INT263918 Binding of PTPRC and Cea 1 0.00 0.37 0 5.00
170 INT280831 Prkaca Positive_regulation of Gene_expression of Crh 1 0.08 0 0 5.00
171 INT232911 Binding of KRT18 and PLAT 1 0.05 1.3 0 5.00
172 INT353125 Negative_regulation of Binding of VEGFA and Kdr 1 0.04 5.92 0 5.00
173 INT244477 CS Regulation of Gene_expression of ATF6 1 0.18 0.07 0 5.00
174 INT197547 Binding of PTS and KEAP1 1 0.08 1.23 0 5.00
175 INT199582 Braf Negative_regulation of Akt1 1 0.00 0.79 0 5.00
176 INT197552 GSTK1 Positive_regulation of NQO1 1 0.09 1.06 0 5.00
177 INT244453 CS Positive_regulation of Gene_expression of TMBIM6 1 0.07 1.3 0 5.00
178 INT244479 CS Positive_regulation of ATF6 1 0.17 1.02 0 5.00
179 INT232915 Binding of KRT8 and PLAT 1 0.04 1.3 0 5.00
180 INT199579 Tnk1 Negative_regulation of Raf1 1 0.01 0.78 0 5.00
181 INT232909 Binding of KRT1 and KRT9 1 0.16 0.5 0 5.00
182 INT175399 Binding of TP53 and SACM1L 1 0.00 2.37 0 5.00
183 INT244481 Binding of ERN1 and ATF6 1 0.17 0.69 0 5.00
184 INT244471 TMBIM6 Negative_regulation of ESR1 1 0.04 0.68 0 5.00
185 INT244460 Binding of CS and Positive_regulation of Positive_regulation of EIF2S2 1 0.13 0.06 0 5.00
186 INT244470 ATF6 Regulation of XBP1 1 0.22 0.69 0 5.00
187 INT280824 Binding of Avp and Crh 1 0.05 0.55 0 5.00
188 INT244466 EIF2AK3 Positive_regulation of Localization of SIL1 1 0.06 0.47 0 5.00
189 INT280847 Avp Regulation of Binding of ELANE 1 0.07 0 0 5.00
190 INT197545 KEAP1 Regulation of NFE2L2 3 0.49 0.8 0 5.00
191 INT280828 Binding of Avp and Avpr2 2 0.15 0.28 0 5.00
192 INT199578 Tnk1 Negative_regulation of Braf 1 0.01 0.78 0 5.00
193 INT244468 CS Positive_regulation of EIF2S2 1 0.16 0.43 0 5.00
194 INT232913 Binding of KRT3 and NBPF14 1 0.01 0.21 0 5.00
195 INT244467 Negative_regulation of CS Positive_regulation of EIF2S2 1 0.11 0.14 0 5.00
196 INT277766 EGFR Regulation of Gene_expression of VEGFA 1 0.54 0.14 0 5.00
197 INT244455 ATF6 Regulation of SIL1 1 0.06 0.69 0 5.00
198 INT244478 Regulation of CS Regulation of XBP1 1 0.20 0.06 0 5.00
199 INT232908 Binding of KRT19 and PLAT 1 0.05 1.31 0 5.00
200 INT232906 Binding of KRT1 and KRT10 1 0.18 0.51 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Small Cell Lung Cancer. They are ordered first by their pain relevance and then by number of times they were reported in Small Cell Lung Cancer. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT13907 Gene_expression of SCLC1 16 0.59 16.58 1.89 100.00
2 INT54565 Binding of SCLC1 12 0.31 20.41 0.81 100.00
3 INT172570 Positive_regulation of SCLC1 5 0.67 6.27 1.5 100.00
4 INT214445 Positive_regulation of Clcn1 1 0.02 2.54 0.08 100.00
5 INT110817 Negative_regulation of SCLC1 3 0.35 2.75 0.36 100.00
6 INT184694 Gene_expression of Usf1 10 0.55 4.27 0.72 100.00
7 INT280793 Gene_expression of Usf2 1 0.23 1.4 0 100.00
8 INT67670 Regulation of SCLC1 3 0.21 1.6 0.59 100.00
9 INT233857 Positive_regulation of Binding of SCLC1 1 0.06 2.37 0.06 100.00
10 INT695 Binding of POMC 304 0.48 56.66 126.85 100.00
11 INT347264 Localization of SCLC1 1 0.22 0.61 0 100.00
12 INT189955 Regulation of Gene_expression of SCLC1 1 0.04 0.68 0 100.00
13 INT13908 Gene_expression of PHOX2B 1 0.25 0.6 0.09 100.00
14 INT113865 Binding of CXADR 35 0.46 3.18 1.12 100.00
15 INT263906 Gene_expression of TMED7-TICAM2 1 0.01 2.8 0 99.98
16 INT263909 Positive_regulation of Gene_expression of TMED7-TICAM2 1 0.01 0.87 0 99.98
17 INT189948 Gene_expression of Pttg1 106 0.76 104.68 1.41 99.96
18 INT94165 Negative_regulation of RB1 30 0.52 27.29 0.51 99.90
19 INT174189 Gene_expression of E2F2 19 0.49 12.58 4.71 99.86
20 INT163283 Gene_expression of E2F1 21 0.71 3.77 2.26 99.86
21 INT260285 Gene_expression of E2F3 6 0.54 2.51 1.13 99.86
22 INT14131 Regulation of HTR1A 34 0.60 9.61 14.74 99.86
23 INT60813 Regulation of HTR1D 10 0.60 3.4 4.67 99.86
24 INT6557 Gene_expression of Eno2 65 0.77 54.42 8.17 99.84
25 INT189949 Regulation of Gene_expression of Pttg1 1 0.60 6.84 0 99.84
26 INT24891 Gene_expression of SYP 55 0.75 45.76 7.53 99.84
27 INT62387 Gene_expression of PTX4 1 0.07 0.49 0.48 99.84
28 INT18630 Transcription of CCK 9 0.71 3 3.73 99.82
29 INT2406 Gene_expression of CCK 85 0.78 28.04 46.67 99.78
30 INT144428 Positive_regulation of Gene_expression of Erbb2 41 0.69 41.4 4.13 99.76
31 INT49439 Gene_expression of Cpox 508 0.73 326.97 130.17 99.76
32 INT6656 Gene_expression of YY1 135 0.75 24.73 72.16 99.74
33 INT53890 Transcription of YY1 8 0.67 1.53 2.88 99.74
34 INT4861 Localization of GRP 84 0.80 8.26 28.03 99.72
35 INT11303 Gene_expression of Avp 116 0.78 39.23 23.88 99.68
36 INT210300 Gene_expression of ELAVL4 10 0.65 5.14 0.49 99.68
37 INT48219 Gene_expression of SLC4A1 34 0.75 33.18 2.84 99.68
38 INT48217 Gene_expression of SLC4A3 22 0.75 21.12 2.17 99.68
39 INT11300 Positive_regulation of Gene_expression of Avp 24 0.50 10.18 2.69 99.68
40 INT126993 Binding of E2F1 5 0.44 1.39 1.12 99.66
41 INT78199 Gene_expression of Neu1 65 0.75 62.88 7.16 99.64
42 INT80174 Positive_regulation of Gene_expression of Neu1 23 0.37 17.82 1.12 99.64
43 INT56749 Gene_expression of PCNA 219 0.77 111.25 18.42 99.60
44 INT53780 Binding of Avp 19 0.48 6.16 2.55 99.60
45 INT306861 Positive_regulation of Negative_regulation of CDC25A 1 0.25 0.71 0.4 99.56
46 INT182427 Binding of E2F2 7 0.23 2.78 1.49 99.54
47 INT62441 Gene_expression of ABCC1 56 0.78 21.01 12.93 99.54
48 INT306835 Regulation of E2F2 1 0.39 2.52 2.62 99.50
49 INT97052 Transcription of Trp53 12 0.64 6.52 1.01 99.50
50 INT275240 Transcription of ENO2 2 0.19 0.35 0.08 99.50
51 INT467 Gene_expression of POMC 1048 0.78 332.8 394.16 99.48
52 INT11159 Gene_expression of EGFR 698 0.78 548.93 25.69 99.48
53 INT11158 Positive_regulation of Gene_expression of EGFR 165 0.70 131.26 4.93 99.48
54 INT3738 Regulation of Epo 25 0.61 13.73 6.18 99.44
55 INT21380 Regulation of Transcription of Avp 10 0.62 2.6 5.46 99.44
56 INT5499 Transcription of Avp 52 0.72 7.98 19.87 99.44
57 INT144430 Gene_expression of Erbb2 137 0.77 103.87 8.66 99.40
58 INT306857 Binding of E2F3 1 0.21 1.22 1.24 99.36
59 INT52021 Regulation of IGHG3 34 0.39 22.43 3.3 99.36
60 INT219492 Negative_regulation of CDC6 2 0.20 1.74 1.31 99.34
61 INT158644 Negative_regulation of CDC25A 2 0.23 2.63 1.55 99.34
62 INT201463 Negative_regulation of CCNE2 7 0.39 3.31 1.36 99.34
63 INT119102 Gene_expression of PDGFRA 13 0.75 11.99 0.81 99.34
64 INT438 Gene_expression of Crh 376 0.78 159.11 169.17 99.32
65 INT443 Localization of POMC 1020 0.81 284.52 443.17 99.32
66 INT6307 Positive_regulation of HTR1D 17 0.67 3.11 7.51 99.32
67 INT6128 Positive_regulation of Localization of POMC 256 0.70 68.77 121.64 99.32
68 INT189947 Regulation of Pttg1 4 0.49 7.18 0 99.28
69 INT94028 Regulation of Twist1 37 0.44 22.41 5.33 99.24
70 INT66491 Regulation of CES2 2 0.45 1.51 0.86 99.24
71 INT93168 Gene_expression of Ttf1 24 0.63 17.18 1.14 99.20
72 INT18990 Positive_regulation of GRP 32 0.70 5.22 11.23 99.16
73 INT97693 Gene_expression of REST 29 0.75 5.51 5.26 99.16
74 INT306875 Localization of CDC6 1 0.34 1.51 1.52 99.12
75 INT306833 Localization of CDC25A 1 0.40 1.51 1.52 99.12
76 INT306844 Localization of CCNE2 6 0.21 3.81 1.52 99.12
77 INT185282 Localization of E2F2 3 0.47 1.92 0.25 99.12
78 INT92434 Phosphorylation of Mapk1 287 0.82 91.65 83.46 99.12
79 INT111462 Negative_regulation of Phosphorylation of Mapk1 45 0.57 19.49 15.59 99.12
80 INT175703 Negative_regulation of E2F2 6 0.38 3.47 2.44 99.04
81 INT306846 Negative_regulation of Binding of E2F3 1 0.24 0.65 0.94 99.04
82 INT306891 Negative_regulation of E2F3 1 0.25 0.65 0.94 99.04
83 INT238440 Negative_regulation of Binding of E2F2 3 0.27 1.09 1.07 99.04
84 INT105336 Regulation of AKT1 52 0.56 32.53 4.89 99.00
85 INT122570 Negative_regulation of Akt1 173 0.59 91.44 25.53 98.84
86 INT60821 Negative_regulation of HTR1D 15 0.57 0.69 5.27 98.80
87 INT78942 Negative_regulation of DDX41 1 0.57 1.79 0.08 98.78
88 INT62360 Positive_regulation of PTHLH 31 0.70 28.23 3.46 98.72
89 INT4207 Regulation of Avp 267 0.62 63.72 115.33 98.68
90 INT306868 Positive_regulation of Gene_expression of E2F1 6 0.46 1.01 1.28 98.68
91 INT189946 Positive_regulation of Gene_expression of Pttg1 14 0.68 23.72 0.38 98.56
92 INT37722 Gene_expression of NCAM1 103 0.75 81.57 14.18 98.56
93 INT68285 Gene_expression of SERPINB3 24 0.75 25.4 0.45 98.56
94 INT480 Negative_regulation of Localization of Avp 151 0.59 27.64 63.72 98.52
95 INT192807 Gene_expression of SSRP1 14 0.49 19.28 1.15 98.46
96 INT184992 Positive_regulation of CDC6 2 0.28 0.7 0.96 98.40
97 INT14132 Negative_regulation of HTR1A 25 0.57 4.93 10.91 98.36
98 INT158442 Gene_expression of Nkx2-1 21 0.59 8.47 1.99 98.28
99 INT61910 Binding of Slc3a2 6 0.01 3 0.7 98.24
100 INT167692 Binding of NCAM1 11 0.36 6.73 1.59 98.16
101 INT477 Localization of Avp 813 0.81 131.58 300.4 98.12
102 INT4860 Positive_regulation of CALCA 148 0.00 73.35 97.61 98.06
103 INT93166 Positive_regulation of Ttf1 4 0.41 3.62 0.08 98.04
104 INT306854 Positive_regulation of CDC25A 3 0.37 1.57 0.82 98.04
105 INT244117 Binding of ELAVL3 1 0.15 5.2 0.42 98.04
106 INT172626 Localization of E2F1 3 0.78 1.97 0.4 98.00
107 INT199681 Gene_expression of SERPINA5 13 0.36 15.42 1.25 98.00
108 INT119880 Binding of Usf1 5 0.20 2.55 1.28 97.96
109 INT280772 Binding of Usf2 1 0.13 0.52 0 97.96
110 INT99547 Positive_regulation of CDKN1B 18 0.67 8.42 1.96 97.88
111 INT120358 Positive_regulation of Positive_regulation of CDKN1B 2 0.49 1.26 0.55 97.88
112 INT1931 Positive_regulation of Gene_expression of POMC 116 0.70 37.26 38.67 97.80
113 INT5497 Positive_regulation of Crh 299 0.70 125.54 131.14 97.76
114 INT20205 Binding of IgG 108 0.46 66.68 8.57 97.68
115 INT38858 Positive_regulation of Gene_expression of SGSM3 5 0.49 4.15 3.05 97.60
116 INT75521 Positive_regulation of Positive_regulation of SGSM3 13 0.67 7.99 13.54 97.60
117 INT93361 Gene_expression of Trp53 208 0.78 175.35 16.65 97.60
118 INT82185 Positive_regulation of Negative_regulation of TP53BP2 1 0.36 1.01 0.96 97.60
119 INT207867 Gene_expression of H2-Ob 1 0.01 5.46 0.18 97.56
120 INT201465 Positive_regulation of CCNE2 6 0.13 3.13 0.92 97.56
121 INT82374 Binding of SYP 13 0.36 13.69 0.85 97.52
122 INT46833 Positive_regulation of SGSM3 56 0.67 24.49 30.31 97.36
123 INT89401 Negative_regulation of Phosphorylation of AKT1 68 0.58 35.61 2.8 97.28
124 INT73253 Binding of Efs 3 0.36 2.4 0.33 97.28
125 INT11318 Gene_expression of Gtf3a 274 0.52 183.82 60.89 97.24
126 INT38859 Gene_expression of SGSM3 14 0.75 12.98 4.09 97.16
127 INT1123 Positive_regulation of CD79A 74 0.70 51.96 7.14 97.12
128 INT122323 Positive_regulation of NOTCH1 36 0.70 35.63 3.7 97.08
129 INT306859 Localization of E2F4 1 0.56 0.65 0.4 97.08
130 INT6163 Negative_regulation of INA 39 0.43 2.9 14.8 97.08
131 INT244562 Gene_expression of EIF2S2 1 0.46 23.74 0 97.04
132 INT2597 Negative_regulation of ACHE 82 0.59 46.36 8.62 96.98
133 INT306880 Localization of NOLC1 2 0.19 6.32 0.54 96.90
134 INT178489 Negative_regulation of Kdr 31 0.42 25.65 0.66 96.84
135 INT199564 Negative_regulation of Phosphorylation of Kdr 1 0.27 1.12 0 96.84
136 INT52020 Negative_regulation of ICA1 7 0.31 1.56 5.71 96.76
137 INT144735 Gene_expression of DDC 8 0.75 3.21 5.31 96.60
138 INT2093 Gene_expression of GAST 50 0.78 32.32 7.98 96.56
139 INT89396 Phosphorylation of AKT1 225 0.82 111.66 19.61 96.44
140 INT199552 Phosphorylation of Kdr 4 0.38 1.27 0 96.28
141 INT15652 Positive_regulation of ENO2 37 0.68 33.39 5.02 96.20
142 INT214 Localization of AVP 370 0.81 208.51 91.09 96.20
143 INT99961 Positive_regulation of SYP 13 0.67 15.13 2.79 96.20
144 INT109327 Negative_regulation of KIT 42 0.57 43.2 2.15 96.20
145 INT159232 Negative_regulation of SYP 4 0.41 4.45 0.38 96.20
146 INT56032 Positive_regulation of NCAM1 38 0.49 26.01 4.68 96.20
147 INT85284 Negative_regulation of ENO2 8 0.58 7.86 2.28 96.20
148 INT85085 Positive_regulation of KIT 36 0.53 30.08 2.17 96.20
149 INT128201 Negative_regulation of NCAM1 10 0.39 7.64 0.74 96.20
150 INT159231 Positive_regulation of PDGFRA 3 0.47 2.39 0.18 96.20
151 INT136182 Negative_regulation of PDGFRA 3 0.43 2.43 0.08 96.20
152 INT185879 Gene_expression of CDC6 9 0.39 5.18 6.46 96.08
153 INT306836 Negative_regulation of Gene_expression of CDC6 1 0.19 1.28 1.88 96.08
154 INT15610 Localization of GOPC 223 0.65 68.26 28.7 96.00
155 INT232960 Negative_regulation of Binding of KRT5 1 0.20 1.68 0 95.96
156 INT263905 Gene_expression of SLN 33 0.63 23.21 0.74 95.92
157 INT263904 Negative_regulation of Gene_expression of SLN 1 0.14 7.18 0.47 95.92
158 INT8531 Transcription of PDYN 56 0.72 19.51 30.99 95.92
159 INT75527 Positive_regulation of Gene_expression of TP53BP2 4 0.38 3.3 1.88 95.84
160 INT82186 Negative_regulation of Negative_regulation of TP53BP2 1 0.33 0.99 0.94 95.84
161 INT244524 Phosphorylation of EIF2S2 1 0.49 11.33 0.2 95.68
162 INT70450 Binding of KRT5 6 0.47 5.72 0.08 95.68
163 INT185905 Gene_expression of CDC25A 2 0.41 4.63 7.29 95.36
164 INT306845 Negative_regulation of Gene_expression of CDC25A 1 0.31 1.44 2.88 95.36
165 INT75522 Gene_expression of TP53BP2 3 0.52 2.74 1.46 95.28
166 INT82184 Negative_regulation of TP53BP2 2 0.33 1.87 1.23 95.28
167 INT199551 Regulation of Rcc1 2 0.01 2.63 0.05 95.28
168 INT1430 Regulation of PDYN 88 0.60 16.99 60.32 95.20
169 INT244568 Positive_regulation of Gene_expression of EIF2S2 1 0.41 12.82 0 95.16
170 INT244563 Positive_regulation of EIF2S2 1 0.41 7.67 0.13 95.16
171 INT72221 Localization of PRKCA 17 0.81 1.23 11.47 95.12
172 INT44550 Positive_regulation of Gene_expression of AVP 38 0.70 22.27 8.62 94.76
173 INT81576 Positive_regulation of Gene_expression of SIL1 5 0.23 7.03 0.27 94.64
174 INT182440 Gene_expression of CCNE2 39 0.53 22.07 7.44 94.40
175 INT201458 Negative_regulation of Gene_expression of CCNE2 3 0.07 1.71 1.96 94.40
176 INT78097 Negative_regulation of Regulation of CALCA 2 0.42 2.02 1.37 94.28
177 INT3679 Gene_expression of AVP 171 0.78 72.9 35.23 94.16
178 INT81575 Gene_expression of SIL1 29 0.25 19.76 1.24 94.16
179 INT73262 Negative_regulation of BCL2 67 0.57 61.01 5.07 94.04
180 INT71151 Regulation of NTRK1 10 0.62 6.65 6.21 93.96
181 INT53889 Negative_regulation of Positive_regulation of YY1 6 0.41 0.57 3.05 93.84
182 INT280802 Gene_expression of Bhlha15 1 0.06 0.5 0 93.84
183 INT189945 Localization of Pttg1 3 0.73 3.02 0.16 93.84
184 INT1624 Gene_expression of Cea 212 0.76 180.44 34.21 93.80
185 INT20622 Gene_expression of LDHA 107 0.76 77.97 16.3 93.76
186 INT171666 Regulation of GOPC 117 0.39 40.41 15.47 93.24
187 INT105960 Gene_expression of Cdh1 41 0.76 22.28 5.56 93.20
188 INT105959 Positive_regulation of Gene_expression of Cdh1 5 0.49 2.65 0.57 93.20
189 INT268709 Positive_regulation of Gene_expression of TUBB 1 0.34 1.19 0 93.08
190 INT268691 Gene_expression of TUBB 2 0.38 1.26 0 93.08
191 INT720 Positive_regulation of POMC 807 0.70 237.37 353.83 93.04
192 INT1196 Positive_regulation of Positive_regulation of POMC 51 0.70 15.99 28.58 93.04
193 INT4241 Regulation of CALCA 87 0.62 28.19 55.29 93.00
194 INT789 Positive_regulation of YY1 69 0.67 14.07 47.06 92.80
195 INT671 Positive_regulation of Cea 221 0.69 164.5 47.79 92.68
196 INT238433 Negative_regulation of Gene_expression of E2F2 2 0.27 1.01 1.07 92.64
197 INT306853 Binding of E2F4 1 0.28 1.37 1.63 92.56
198 INT217827 Gene_expression of E2F5 2 0.46 2.3 1.21 92.56
199 INT306872 Localization of E2F5 1 0.42 0.65 0.4 92.56
200 INT1429 Gene_expression of PDYN 308 0.78 61.33 175.65 92.52
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