D:Small Cell Lung Carcinoma

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Disease Term
Synonyms CARCINOMA SMALL CELL LUNG, Oat Cell Carcinoma Of Lung, Oat Cell Lung Cancer, Small Cell Lung Cancer
Documents 112
Hot Single Events 113
Hot Interactions 19

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Small Cell Lung Carcinoma. They are ordered first by their relevance to Small Cell Lung Carcinoma and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT235649 TP73 Regulation of EFNA1 1 0.09 0.97 0 99.68
2 INT235651 TP73 Regulation of EPHA2 1 0.15 0.98 0 99.68
3 INT235647 TP63 Regulation of EPHA2 1 0.15 0.97 0 99.36
4 INT235646 TP63 Regulation of EFNA1 1 0.09 0.97 0 99.36
5 INT235645 TP53 Regulation of EPHA2 1 0.10 0.97 0 99.16
6 INT235650 TP53 Regulation of EFNA1 1 0.06 0.97 0 99.16
7 INT72817 Agt Negative_regulation of Avp 1 0.07 0.34 0.14 98.28
8 INT72818 Edn3 Negative_regulation of Avp 1 0.08 0.34 0.14 98.28
9 INT101060 TNF Positive_regulation of Binding of Nfkb1 and Nfkb1 1 0.07 1.22 0.18 94.80
10 INT101062 TNF Positive_regulation of Binding of Nfkb1 1 0.13 1.22 0.18 94.80
11 INT101063 TNF Positive_regulation of Localization of Nfkb1 1 0.13 1.22 0.18 94.80
12 INT72819 Regulation of EDN3 Positive_regulation of Avp 1 0.28 0.32 0.13 91.68
13 INT280835 Usf1 Positive_regulation of Gene_expression of Avp 1 0.03 1.06 0 91.52
14 INT72820 EDN3 Positive_regulation of Avp 1 0.31 0.64 0.27 91.12
15 INT280830 Binding of Avp and Usf2 1 0.02 0.53 0 89.88
16 INT280812 Usf2 Positive_regulation of Gene_expression of Avp 1 0.03 0.52 0 89.88
17 INT280829 Binding of Tcf12 and Usf2 1 0.00 0.53 0 89.88
18 INT280851 Binding of Avp and Usf2 Positive_regulation of Gene_expression of Avp 1 0.00 0.53 0 89.88
19 INT280844 Binding of Avp and Tcf12 1 0.00 0.52 0 86.48
20 INT188201 OSM Positive_regulation of Phosphorylation of STAT3 1 0.40 0.24 0.21 66.56
21 INT235648 Binding of EFNA1 and EPHA2 1 0.23 1.3 0 63.96
22 INT108332 EGF Positive_regulation of Phosphorylation of MAPK1 5 0.48 1.85 0.45 61.08
23 INT188203 EGF Positive_regulation of Protein_catabolism of OSM 1 0.30 0.17 0.21 61.08
24 INT188195 GOPC Positive_regulation of MAPK1 2 0.21 0.32 0.22 54.24
25 INT244116 ELAVL3 Negative_regulation of MUC1 1 0.09 3.41 0.15 50.00
26 INT244461 CS Positive_regulation of ESR1 1 0.06 1.15 0.05 43.04
27 INT188209 OSM Positive_regulation of MAPK1 1 0.35 0.47 0.27 30.40
28 INT188199 IL6 Positive_regulation of MAPK1 1 0.27 0.25 0.16 30.40
29 INT215096 Binding of Hmgb1 and Tlr2 9 0.38 11.61 1.61 25.00
30 INT188197 LIF Positive_regulation of STAT3 1 0.35 0.27 0.12 23.36
31 INT188193 Negative_regulation of EGF Positive_regulation of MAPK1 1 0.28 0.54 0.34 20.72
32 INT188204 Negative_regulation of IL6 Positive_regulation of STAT3 1 0.28 0.54 0.34 20.72
33 INT144035 IL6 Positive_regulation of STAT3 4 0.31 2.58 0.56 20.32
34 INT156831 EGF Positive_regulation of MAPK1 2 0.45 0.27 0.33 18.28
35 INT280815 Vmn1r66 Negative_regulation of Gene_expression of Avp 1 0.00 0.09 0 13.92
36 INT280849 REST Negative_regulation of Gene_expression of Avp 1 0.09 0.09 0 10.80
37 INT280848 Binding of REST and Rest 1 0.02 0.09 0 10.80
38 INT280837 Binding of Rest and Negative_regulation of Gene_expression of Avp 1 0.00 0.09 0 10.56
39 INT149117 Binding of CD80 and CTLA4 31 0.52 12.7 7.73 5.00
40 INT194647 Binding of CD28 and CD80 15 0.40 4.9 3.22 5.00
41 INT60626 Crh Positive_regulation of Localization of Pomc 7 0.54 2.3 1.99 5.00
42 INT188196 LIF Regulation of MAPK1 1 0.21 2.26 0.87 5.00
43 INT188214 OSM Regulation of MAPK1 1 0.20 2.27 0.87 5.00
44 INT122191 Binding of Crh and Ucn 4 0.36 0.79 0.82 5.00
45 INT172097 Binding of HLA-E and Trav6-3 10 0.02 3.71 0.71 5.00
46 INT122190 Binding of Crhr1 and Ucn 4 0.49 0.65 0.67 5.00
47 INT145661 Ptger2 Positive_regulation of Gene_expression of VEGFA 4 0.27 2.73 0.6 5.00
48 INT351076 IK Positive_regulation of Gene_expression of Ucp3 1 0.00 0.8 0.58 5.00
49 INT93063 Binding of gr and Jun 3 0.14 0.79 0.57 5.00
50 INT149473 Avp Positive_regulation of Localization of Pomc 4 0.48 2.64 0.56 5.00
51 INT190702 CD40 Positive_regulation of Gene_expression of F3 1 0.00 1.4 0.55 5.00
52 INT280826 Il6 Positive_regulation of Localization of Avp 1 0.01 0.64 0.47 5.00
53 INT188194 OSM Regulation of IL6 1 0.16 1.12 0.43 5.00
54 INT188205 OSM Regulation of LIF 1 0.09 1.12 0.43 5.00
55 INT188211 IL6 Regulation of MAPK1 1 0.16 1.13 0.43 5.00
56 INT188207 LIF Regulation of IL6 1 0.17 1.12 0.43 5.00
57 INT122188 Binding of Crh and Ucn2 2 0.22 0.29 0.38 5.00
58 INT122189 Binding of Crhr1 and Ucn2 2 0.08 0.27 0.36 5.00
59 INT280808 Prkcg Positive_regulation of Transcription of Fos 1 0.02 0.06 0.33 5.00
60 INT280838 Binding of Crh and gr 1 0.06 0 0.33 5.00
61 INT280814 Positive_regulation of Mapk1 Positive_regulation of Transcription of Fos 1 0.02 0.06 0.33 5.00
62 INT280827 Positive_regulation of Fos Positive_regulation of Avp 1 0.02 0.08 0.28 5.00
63 INT280825 Mapk1 Positive_regulation of Avp 1 0.01 0.08 0.28 5.00
64 INT280807 Mapk1 Positive_regulation of Positive_regulation of Prkcg 1 0.01 0.08 0.28 5.00
65 INT280832 Binding of Crh and Ucn3 1 0.16 0.07 0.27 5.00
66 INT293900 TYRP1 Regulation of IGKC 1 0.01 0.11 0.27 5.00
67 INT280850 Binding of Crh and Ucn Positive_regulation of Negative_regulation of Crh 1 0.26 0.06 0.27 5.00
68 INT280822 Jun Regulation of Regulation of Crh 1 0.20 0.08 0.27 5.00
69 INT280805 Positive_regulation of Prkcg Positive_regulation of Avp 1 0.01 0.16 0.26 5.00
70 INT280811 Binding of Crhr1 and Ucn3 1 0.08 0.05 0.25 5.00
71 INT235976 Binding of APC and Trav6-3 2 0.01 2.62 0.24 5.00
72 INT188200 IL6ST Positive_regulation of STAT3 1 0.25 0.38 0.23 5.00
73 INT121050 Crh Regulation of Localization of Pomc 4 0.43 0.6 0.22 5.00
74 INT280820 S100a8 Positive_regulation of Gene_expression of Crh 1 0.01 0.65 0.19 5.00
75 INT258289 Hmgb1 Positive_regulation of Tlr2 4 0.48 3.61 0.19 5.00
76 INT280839 Il6 Positive_regulation of Gene_expression of Crh 1 0.09 0.1 0.19 5.00
77 INT280833 Il1 Positive_regulation of Gene_expression of Crh 1 0.05 0.09 0.17 5.00
78 INT280846 Crh Positive_regulation of Localization of POMC 1 0.03 0.37 0.16 5.00
79 INT280813 Binding of Avp and S100a8 1 0.00 0.28 0.15 5.00
80 INT293901 Positive_regulation of TYRP1 Regulation of IGKC 1 0.02 0.06 0.15 5.00
81 INT280819 Binding of Creb1 and gr 1 0.01 0 0.13 5.00
82 INT344314 PDPN Positive_regulation of Phosphorylation of MAPK8 1 0.35 0.67 0.13 5.00
83 INT280809 Binding of gr and Rela 1 0.00 0 0.13 5.00
84 INT188198 OSM Positive_regulation of STAT3 1 0.52 0.24 0.12 5.00
85 INT299754 Binding of APC and CTLA4 2 0.08 0.97 0.11 5.00
86 INT188202 HBE1 Positive_regulation of MAPK1 1 0.01 0.14 0.11 5.00
87 INT188192 HBE1 Positive_regulation of LY6E 1 0.00 0.14 0.11 5.00
88 INT280836 Gene_expression of Fos Positive_regulation of Crh 1 0.09 0.17 0.1 5.00
89 INT280841 Jun Positive_regulation of Gene_expression of Crh 1 0.35 0.16 0.1 5.00
90 INT244452 CS Positive_regulation of Phosphorylation of EIF2S2 1 0.21 2.07 0.09 5.00
91 INT280821 Son Regulation of Gene_expression of gr 1 0.01 0.18 0.08 5.00
92 INT320267 CCNA2 Positive_regulation of CDK1 1 0.12 1.08 0.08 5.00
93 INT244449 CS Regulation of Gene_expression of ATF4 1 0.15 0.83 0.08 5.00
94 INT232917 Binding of KRT8 and KRT19 2 0.16 1.04 0.08 5.00
95 INT188210 EGF Positive_regulation of OSM 1 0.28 0 0.07 5.00
96 INT188208 EGF Regulation of STAT3 1 0.46 0 0.07 5.00
97 INT280810 Avp Negative_regulation of Gene_expression of Pomc 1 0.02 0.22 0.06 5.00
98 INT280816 Crh Positive_regulation of Gene_expression of Pomc 1 0.15 0.28 0.06 5.00
99 INT280818 Jun Positive_regulation of Avp 1 0.06 0.23 0.06 5.00
100 INT280834 Negative_regulation of Jun Positive_regulation of Avp 1 0.05 0.23 0.06 5.00
101 INT258290 Hmgb1 Regulation of Positive_regulation of Tlr2 1 0.46 1.04 0.05 5.00
102 INT344345 Mapk14 Regulation of Gene_expression of VEGFA 1 0.01 0.37 0.05 5.00
103 INT232914 Binding of KRT2 and KRT7 1 0.15 0.63 0.05 5.00
104 INT232916 Binding of KRT2 and KRT19 1 0.21 0.62 0.05 5.00
105 INT232907 Binding of KRT7 and KRT8 1 0.09 0.63 0.05 5.00
106 INT280843 Binding of Crem and Crh 1 0.03 0.22 0.04 5.00
107 INT280817 Binding of Cdx1 and Crh 1 0.02 0.21 0.04 5.00
108 INT293899 UPF1 Positive_regulation of Gene_expression of APOB 1 0.01 0 0.04 5.00
109 INT244464 EIF2AK3 Positive_regulation of Positive_regulation of EIF2S2 1 0.17 0.37 0.04 5.00
110 INT244463 EIF2AK3 Regulation of Phosphorylation of EIF2S2 1 0.09 0.37 0.04 5.00
111 INT344312 PDPN Positive_regulation of ITK 1 0.05 0.26 0.04 5.00
112 INT344317 PDPN Negative_regulation of VEGFA 1 0.08 0.67 0.03 5.00
113 INT344308 Positive_regulation of PDPN Negative_regulation of VEGFA 1 0.09 0.24 0.03 5.00
114 INT244474 CS Regulation of XBP1 1 0.20 0.15 0 5.00
115 INT280823 Positive_regulation of Prkaca Positive_regulation of Gene_expression of Crh 1 0.08 0.11 0 5.00
116 INT232918 Binding of KRT2 and KRT8 1 0.17 0.59 0 5.00
117 INT244480 CS Negative_regulation of Gene_expression of XBP1 1 0.16 0.11 0 5.00
118 INT244462 XBP1 Regulation of Gene_expression of DNAJB11 1 0.11 0 0 5.00
119 INT244454 Binding of EIF2AK3 and SIL1 1 0.05 0.41 0 5.00
120 INT244476 CS Positive_regulation of ATF3 1 0.13 0.13 0 5.00
121 INT244469 CS Positive_regulation of PPP1R15A 1 0.08 0.12 0 5.00
122 INT344315 MAPK8 Positive_regulation of Negative_regulation of PDPN 1 0.35 0.56 0 5.00
123 INT244457 CS Positive_regulation of Gene_expression of ESR1 1 0.07 0.67 0 5.00
124 INT280840 Avp Regulation of Localization of Pomc 1 0.02 0.16 0 5.00
125 INT244458 CS Positive_regulation of ERN1 1 0.17 0.71 0 5.00
126 INT244475 Binding of CS and Positive_regulation of EIF2S2 1 0.11 0.07 0 5.00
127 INT244473 ATF6 Regulation of Gene_expression of DNAJB11 1 0.10 0 0 5.00
128 INT301675 Binding of APC and HLA-E 1 0.01 1.48 0 5.00
129 INT192956 Binding of CD2 and KIT 1 0.03 0.62 0 5.00
130 INT344310 MAPK8 Positive_regulation of Negative_regulation of VEGFA 1 0.08 0.57 0 5.00
131 INT280845 Binding of ELANE and Avp 1 0.06 0 0 5.00
132 INT244459 ERN1 Regulation of Positive_regulation of MAPK8 1 0.03 0.47 0 5.00
133 INT244450 TMBIM6 Negative_regulation of Gene_expression of ESR1 1 0.04 0.68 0 5.00
134 INT286988 Twist1 Positive_regulation of EGFR 1 0.17 2.01 0 5.00
135 INT280806 Avpr1b Positive_regulation of Localization of Pomc 1 0.19 0.17 0 5.00
136 INT232912 Binding of KRT4 and KRT13 1 0.07 0.06 0 5.00
137 INT232910 Binding of KRT12 and KRT76 1 0.39 0.2 0 5.00
138 INT344313 PDPN Positive_regulation of VEGFA 1 0.09 0.8 0 5.00
139 INT301674 Binding of APC and CD80 1 0.01 0.53 0 5.00
140 INT192955 Binding of KIT and VCAM1 1 0.05 0.63 0 5.00
141 INT280831 Prkaca Positive_regulation of Gene_expression of Crh 1 0.08 0 0 5.00
142 INT232911 Binding of KRT18 and PLAT 1 0.05 1.3 0 5.00
143 INT244477 CS Regulation of Gene_expression of ATF6 1 0.18 0.07 0 5.00
144 INT344319 MAPK8 Positive_regulation of PDPN 1 0.35 0.5 0 5.00
145 INT244453 CS Positive_regulation of Gene_expression of TMBIM6 1 0.07 1.3 0 5.00
146 INT244479 CS Positive_regulation of ATF6 1 0.17 1.02 0 5.00
147 INT232915 Binding of KRT8 and PLAT 1 0.04 1.3 0 5.00
148 INT301677 Binding of APC and CD8A 1 0.03 1.48 0 5.00
149 INT232909 Binding of KRT1 and KRT9 1 0.16 0.5 0 5.00
150 INT244481 Binding of ERN1 and ATF6 1 0.17 0.69 0 5.00
151 INT244471 TMBIM6 Negative_regulation of ESR1 1 0.04 0.68 0 5.00
152 INT244460 Binding of CS and Positive_regulation of Positive_regulation of EIF2S2 1 0.13 0.06 0 5.00
153 INT244470 ATF6 Regulation of XBP1 1 0.22 0.69 0 5.00
154 INT280824 Binding of Avp and Crh 1 0.05 0.55 0 5.00
155 INT244466 EIF2AK3 Positive_regulation of Localization of SIL1 1 0.06 0.47 0 5.00
156 INT280847 Avp Regulation of Binding of ELANE 1 0.07 0 0 5.00
157 INT280828 Binding of Avp and Avpr2 2 0.15 0.28 0 5.00
158 INT344307 PDPN Negative_regulation of Gene_expression of VEGFA 1 0.08 0.36 0 5.00
159 INT344318 PDPN Positive_regulation of Positive_regulation of RHOA 1 0.11 0.92 0 5.00
160 INT189992 Binding of Ptger2 and Pawr 1 0.00 2.89 0 5.00
161 INT244468 CS Positive_regulation of EIF2S2 1 0.16 0.43 0 5.00
162 INT232913 Binding of KRT3 and NBPF14 1 0.01 0.21 0 5.00
163 INT244467 Negative_regulation of CS Positive_regulation of EIF2S2 1 0.11 0.14 0 5.00
164 INT244455 ATF6 Regulation of SIL1 1 0.06 0.69 0 5.00
165 INT301676 Binding of CD8A and HLA-E 1 0.02 2.24 0 5.00
166 INT244478 Regulation of CS Regulation of XBP1 1 0.20 0.06 0 5.00
167 INT232908 Binding of KRT19 and PLAT 1 0.05 1.31 0 5.00
168 INT232906 Binding of KRT1 and KRT10 1 0.18 0.51 0 5.00
169 INT244482 CS Positive_regulation of Transcription of ATF3 1 0.13 0.13 0 5.00
170 INT244472 CS Negative_regulation of Binding of XBP1 1 0.19 1.07 0 5.00
171 INT344316 VEGFA Positive_regulation of PDPN 1 0.09 0.4 0 5.00
172 INT244451 TMBIM6 Negative_regulation of Gene_expression of XBP1 1 0.13 0.68 0 5.00
173 INT344311 PDPN Positive_regulation of Negative_regulation of VEGFA 1 0.09 0.81 0 5.00
174 INT244465 Binding of EIF2AK3 and ATF6 1 0.14 0.69 0 5.00
175 INT189993 Binding of Bcl2 and Ptger2 1 0.00 1.43 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Small Cell Lung Carcinoma. They are ordered first by their pain relevance and then by number of times they were reported in Small Cell Lung Carcinoma. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT54565 Binding of SCLC1 12 0.31 20.41 0.81 99.96
2 INT467 Gene_expression of POMC 1048 0.78 332.8 394.16 99.84
3 INT8571 Gene_expression of B3GAT1 54 0.75 36.85 15.98 99.84
4 INT68285 Gene_expression of SERPINB3 24 0.75 25.4 0.45 99.64
5 INT1429 Gene_expression of PDYN 308 0.78 61.33 175.65 99.60
6 INT138671 Gene_expression of TPH2 35 0.78 7.34 6.03 99.60
7 INT52984 Localization of MIR592 1 0.41 0.17 0.37 99.58
8 INT11303 Gene_expression of Avp 116 0.78 39.23 23.88 99.48
9 INT53780 Binding of Avp 19 0.48 6.16 2.55 99.48
10 INT114362 Localization of Hmgb1 127 0.78 120.28 23.26 99.36
11 INT94028 Regulation of Twist1 37 0.44 22.41 5.33 99.32
12 INT4861 Localization of GRP 84 0.80 8.26 28.03 99.32
13 INT109327 Negative_regulation of KIT 42 0.57 43.2 2.15 99.08
14 INT214 Localization of AVP 370 0.81 208.51 91.09 99.04
15 INT6129 Positive_regulation of Localization of AVP 63 0.70 30.44 16.64 99.04
16 INT73223 Gene_expression of UPF1 78 0.41 31.44 9.94 99.04
17 INT265575 Binding of Msc 11 0.30 7.66 0.34 98.96
18 INT192958 Negative_regulation of IGF1R 8 0.30 6.35 0.21 98.92
19 INT480 Negative_regulation of Localization of Avp 151 0.59 27.64 63.72 98.28
20 INT138672 Transcription of TPH2 5 0.69 2.99 2.34 97.92
21 INT477 Localization of Avp 813 0.81 131.58 300.4 97.88
22 INT71786 Phosphorylation of MAPK1 256 0.82 110.09 46.17 97.20
23 INT75521 Positive_regulation of Positive_regulation of SGSM3 13 0.67 7.99 13.54 97.20
24 INT38858 Positive_regulation of Gene_expression of SGSM3 5 0.49 4.15 3.05 97.20
25 INT186063 Phosphorylation of SOAT1 29 0.28 11.77 5.34 97.20
26 INT82185 Positive_regulation of Negative_regulation of TP53BP2 1 0.36 1.01 0.96 97.20
27 INT46833 Positive_regulation of SGSM3 56 0.67 24.49 30.31 96.96
28 INT78199 Gene_expression of Neu1 65 0.75 62.88 7.16 96.80
29 INT80174 Positive_regulation of Gene_expression of Neu1 23 0.37 17.82 1.12 96.80
30 INT38859 Gene_expression of SGSM3 14 0.75 12.98 4.09 96.76
31 INT73502 Positive_regulation of IL10 154 0.69 124.87 43.5 96.44
32 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 96.08
33 INT65536 Negative_regulation of Positive_regulation of Nfkb1 77 0.59 38.86 33.33 96.08
34 INT65054 Positive_regulation of Nfkb1 285 0.70 149.33 126.73 96.08
35 INT19929 Negative_regulation of Positive_regulation of TNF 52 0.59 38.16 16.51 96.08
36 INT4207 Regulation of Avp 267 0.62 63.72 115.33 96.04
37 INT6128 Positive_regulation of Localization of POMC 256 0.70 68.77 121.64 95.64
38 INT75527 Positive_regulation of Gene_expression of TP53BP2 4 0.38 3.3 1.88 95.44
39 INT82186 Negative_regulation of Negative_regulation of TP53BP2 1 0.33 0.99 0.94 95.44
40 INT92398 Negative_regulation of Localization of Nfkb1 17 0.42 11.24 5.4 95.16
41 INT443 Localization of POMC 1020 0.81 284.52 443.17 94.92
42 INT75522 Gene_expression of TP53BP2 3 0.52 2.74 1.46 94.88
43 INT82184 Negative_regulation of TP53BP2 2 0.33 1.87 1.23 94.88
44 INT72746 Localization of Avpr1a 4 0.73 2.54 0.73 94.08
45 INT438 Gene_expression of Crh 376 0.78 159.11 169.17 94.00
46 INT235660 Gene_expression of EPHA2 27 0.75 23.46 0.4 93.84
47 INT235655 Positive_regulation of Gene_expression of EPHA2 14 0.67 13.48 0.35 93.84
48 INT65058 Binding of Nfkb1 36 0.45 19.87 10.02 93.48
49 INT351074 Negative_regulation of Binding of Timp1 1 0.04 1.14 0.09 92.88
50 INT78480 Localization of Nfkb1 39 0.80 23.14 13.64 92.12
51 INT30 Gene_expression of Gast 158 0.78 99 41.45 92.00
52 INT48692 Binding of VEGFA 345 0.48 210.3 21.31 91.76
53 INT85084 Gene_expression of KRT19 66 0.73 42.56 1.82 91.60
54 INT119880 Binding of Usf1 5 0.20 2.55 1.28 91.52
55 INT69029 Gene_expression of PTPRC 127 0.75 74.26 11.57 90.88
56 INT78942 Negative_regulation of DDX41 1 0.57 1.79 0.08 90.88
57 INT86187 Positive_regulation of AKT1 199 0.69 122.13 19.44 90.80
58 INT19795 Positive_regulation of EGFR 161 0.70 103.69 11.55 90.80
59 INT1931 Positive_regulation of Gene_expression of POMC 116 0.70 37.26 38.67 90.68
60 INT695 Binding of POMC 304 0.48 56.66 126.85 90.64
61 INT24820 Positive_regulation of Binding of POMC 9 0.67 2.98 4.6 90.64
62 INT1586 Regulation of Binding of POMC 7 0.45 1.14 2.61 90.64
63 INT130603 Binding of Timp1 9 0.35 8.52 3.04 90.32
64 INT235656 Positive_regulation of Gene_expression of EFNA1 1 0.40 8.86 0 90.32
65 INT244511 Regulation of EIF2S2 1 0.37 4.46 0 90.28
66 INT235659 Gene_expression of EFNA1 1 0.45 22.92 0.06 89.96
67 INT280772 Binding of Usf2 1 0.13 0.52 0 89.88
68 INT244562 Gene_expression of EIF2S2 1 0.46 23.74 0 89.72
69 INT37541 Gene_expression of SPP1 113 0.77 68.54 11.35 89.32
70 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 89.32
71 INT17401 Gene_expression of IGF1 475 0.78 232.18 62.07 89.32
72 INT39758 Gene_expression of Fn1 57 0.65 34.38 6.02 89.32
73 INT280793 Gene_expression of Usf2 1 0.23 1.4 0 89.28
74 INT184694 Gene_expression of Usf1 10 0.55 4.27 0.72 88.96
75 INT11300 Positive_regulation of Gene_expression of Avp 24 0.50 10.18 2.69 88.96
76 INT4053 Regulation of GRP 27 0.58 5.57 13.76 88.96
77 INT235657 Localization of EFNA1 1 0.43 0.9 0 86.48
78 INT720 Positive_regulation of POMC 807 0.70 237.37 353.83 85.92
79 INT1196 Positive_regulation of Positive_regulation of POMC 51 0.70 15.99 28.58 85.92
80 INT8531 Transcription of PDYN 56 0.72 19.51 30.99 85.88
81 INT235652 Localization of EPHA2 1 0.72 0.89 0 85.36
82 INT14737 Gene_expression of FN1 117 0.78 78.74 18.99 84.80
83 INT628 Negative_regulation of GAST 10 0.58 4.44 2.08 84.56
84 INT1562 Localization of Crh 499 0.81 126.74 236.68 84.00
85 INT244568 Positive_regulation of Gene_expression of EIF2S2 1 0.41 12.82 0 83.60
86 INT244563 Positive_regulation of EIF2S2 1 0.41 7.67 0.13 83.60
87 INT91370 Phosphorylation of STAT3 123 0.82 49.25 8.42 83.32
88 INT115193 Positive_regulation of Phosphorylation of STAT3 30 0.64 11.37 2.2 83.32
89 INT5056 Gene_expression of IFNG 216 0.78 137.52 74.57 82.96
90 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 82.88
91 INT2243 Localization of GAST 67 0.81 34.54 16.19 82.80
92 INT148121 Gene_expression of KRT8 35 0.65 29.07 1.05 82.76
93 INT83479 Gene_expression of KRT18 30 0.65 27.29 1 82.60
94 INT97128 Localization of SPP1 32 0.80 21.75 4.02 82.36
95 INT104250 Positive_regulation of Gene_expression of SPP1 17 0.69 13.22 1.44 82.36
96 INT111477 Gene_expression of KRT7 90 0.74 86.76 4.07 82.04
97 INT320271 Positive_regulation of Localization of IBSP 1 0.02 1.06 0.06 81.96
98 INT207722 Localization of IBSP 4 0.22 2.19 0.06 81.96
99 INT119671 Gene_expression of IBSP 10 0.58 4.31 1.26 81.60
100 INT175644 Positive_regulation of Gene_expression of IBSP 6 0.23 3.95 0.06 81.60
101 INT13908 Gene_expression of PHOX2B 1 0.25 0.6 0.09 81.52
102 INT18898 Positive_regulation of CHGA 38 0.67 28.99 4.86 81.48
103 INT624 Positive_regulation of GAST 28 0.70 15.61 4.73 81.48
104 INT56298 Gene_expression of IL4 306 0.78 182.18 72.92 81.44
105 INT69158 Localization of IL4 48 0.71 31.3 11.98 81.44
106 INT114363 Positive_regulation of Hmgb1 50 0.67 48.92 8.15 81.40
107 INT21380 Regulation of Transcription of Avp 10 0.62 2.6 5.46 81.12
108 INT73498 Gene_expression of IL13 117 0.44 83.85 32.26 80.96
109 INT280802 Gene_expression of Bhlha15 1 0.06 0.5 0 80.92
110 INT74423 Localization of IL10 91 0.80 61.6 22.95 80.80
111 INT5499 Transcription of Avp 52 0.72 7.98 19.87 80.68
112 INT7886 Regulation of Localization of Avp 146 0.62 14.53 72.99 80.64
113 INT13907 Gene_expression of SCLC1 16 0.59 16.58 1.89 80.48
114 INT184749 Gene_expression of Car9 9 0.31 9.45 0.14 79.88
115 INT90875 Negative_regulation of CCND1 31 0.42 26.22 2.66 79.20
116 INT65960 Gene_expression of BCL2 352 0.78 312.03 30.73 78.88
117 INT109403 Regulation of Gene_expression of BCL2 31 0.60 31.22 3.4 78.88
118 INT14831 Negative_regulation of TNC 18 0.50 8.71 4.61 77.36
119 INT233009 Binding of KRT13 1 0.16 1.13 0 77.24
120 INT225960 Gene_expression of KRT13 4 0.39 2.47 0 77.24
121 INT10248 Gene_expression of KRT20 436 0.78 231.96 32.88 77.08
122 INT20632 Gene_expression of TNC 72 0.78 30.43 13.16 76.68
123 INT187628 Gene_expression of KRT14 15 0.75 11.54 0.1 76.32
124 INT38672 Binding of KRT20 69 0.39 48.01 6.31 76.00
125 INT159190 Gene_expression of KRT5 31 0.65 26.67 0.56 76.00
126 INT97245 Gene_expression of AKT1 217 0.77 119.63 15.59 75.84
127 INT21685 Gene_expression of ras 115 0.66 85.6 7.76 75.84
128 INT250707 Gene_expression of PIK3CB 15 0.31 5.4 1.34 75.84
129 INT132521 Gene_expression of BRAF 14 0.65 13.59 0.73 75.84
130 INT1430 Regulation of PDYN 88 0.60 16.99 60.32 75.52
131 INT11587 Gene_expression of CSF2 645 0.78 544.38 93.89 75.28
132 INT116528 Gene_expression of HMOX1 106 0.78 86.13 12.8 75.28
133 INT2451 Positive_regulation of Avp 355 0.70 102.66 147.69 75.00
134 INT1273 Gene_expression of Avp 356 0.78 90.56 138.7 75.00
135 INT3679 Gene_expression of AVP 171 0.78 72.9 35.23 75.00
136 INT14131 Regulation of HTR1A 34 0.60 9.61 14.74 75.00
137 INT6307 Positive_regulation of HTR1D 17 0.67 3.11 7.51 75.00
138 INT60813 Regulation of HTR1D 10 0.60 3.4 4.67 75.00
139 INT9222 Gene_expression of Span 2 0.08 0.64 0.68 75.00
140 INT54561 Binding of Span 1 0.05 1.19 0.2 75.00
141 INT72370 Gene_expression of Timp1 82 0.65 57.52 24.16 74.80
142 INT258283 Positive_regulation of Positive_regulation of Hmgb1 3 0.44 3.1 0.3 73.60
143 INT49134 Gene_expression of Grin1 270 0.78 84.78 148.61 73.44
144 INT111161 Positive_regulation of EFNA1 6 0.40 4.62 0.68 73.32
145 INT235658 Positive_regulation of EPHA2 4 0.67 3.42 0.32 73.32
146 INT132822 Localization of IL13 26 0.67 22.85 6.66 73.12
147 INT42707 Gene_expression of Tbce 24 0.65 12.92 7.93 72.64
148 INT12339 Localization of IL8 437 0.81 251.87 117.39 72.56
149 INT19777 Binding of Crh 16 0.40 6.65 4.36 72.24
150 INT12082 Localization of IL6 365 0.81 241.78 105.78 72.08
151 INT101061 Positive_regulation of BDP1 2 0.03 1.53 0.18 71.92
152 INT260144 Gene_expression of CLDN17 1 0.01 6.35 0 71.28
153 INT235654 Binding of EPHA2 5 0.36 4.26 0 70.96
154 INT118286 Binding of EFNA1 3 0.21 4.95 1.55 70.96
155 INT78023 Gene_expression of DDX41 13 0.65 23.55 3.84 68.32
156 INT78941 Positive_regulation of DDX41 4 0.45 2.46 0.23 68.32
157 INT203491 Gene_expression of Msc 40 0.64 36.05 1.35 68.28
158 INT152681 Gene_expression of PDPN 29 0.65 23.06 0.18 68.08
159 INT86383 Negative_regulation of EGFR 258 0.59 173.94 13.32 66.84
160 INT190696 Gene_expression of Prame 1 0.75 2.4 0.03 66.80
161 INT8224 Gene_expression of CHGA 73 0.75 53.63 12.31 65.92
162 INT6557 Gene_expression of Eno2 65 0.77 54.42 8.17 65.92
163 INT48960 Gene_expression of SCG2 16 0.68 4.41 4.33 65.92
164 INT54740 Positive_regulation of Localization of Crh 10 0.47 7.27 3.01 64.56
165 INT4419 Gene_expression of GOT1 20 0.65 22.53 2.53 64.28
166 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 64.04
167 INT7584 Gene_expression of Crh 112 0.78 39.15 25.33 63.60
168 INT8075 Localization of Crh 64 0.81 25.41 19.45 63.60
169 INT84685 Regulation of BCL2 67 0.60 72.96 6.65 62.84
170 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98 62.72
171 INT80124 Negative_regulation of VEGFA 450 0.58 311.19 44.53 62.68
172 INT116950 Negative_regulation of MAPK8 103 0.57 44.48 17.53 62.68
173 INT28361 Gene_expression of TP53 443 0.78 384.86 28.8 61.60
174 INT8068 Gene_expression of RASGRP1 29 0.54 15.1 1.37 61.28
175 INT219001 Gene_expression of ERCC1 12 0.54 3.77 0.38 60.52
176 INT83733 Gene_expression of TUBB3 12 0.24 4.32 0.3 60.52
177 INT184651 Gene_expression of RRM1 6 0.48 3.46 0.15 60.52
178 INT190695 Localization of Abnormal 1 0.01 2.03 0.37 59.44
179 INT188236 Protein_catabolism of OSM 1 0.63 0.17 0.21 59.28
180 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 58.48
181 INT1199 Positive_regulation of INS 579 0.70 399.64 50.43 58.48
182 INT8347 Gene_expression of SST 181 0.78 104.59 65.45 57.32
183 INT2109 Negative_regulation of Gene_expression of LIF 4 0.41 0.89 0.66 56.68
184 INT221083 Localization of CES2 2 0.80 1.48 0.03 56.68
185 INT2111 Gene_expression of LIF 34 0.77 16.82 6.76 55.80
186 INT9408 Positive_regulation of Crp 296 0.69 242.27 57.35 55.72
187 INT74261 Gene_expression of BMPER 5 0.75 0.63 0 55.44
188 INT11159 Gene_expression of EGFR 698 0.78 548.93 25.69 55.40
189 INT232983 Negative_regulation of KRT13 1 0.26 2.44 0 54.80
190 INT71789 Positive_regulation of MAPK1 396 0.70 234.44 89.27 54.24
191 INT37530 Regulation of Salpa1 8 0.59 4.79 1.19 52.48
192 INT79395 Gene_expression of Twist1 193 0.77 100.06 26.34 50.68
193 INT22708 Gene_expression of MUC1 297 0.78 232.71 24.19 50.00
194 INT62441 Gene_expression of ABCC1 56 0.78 21.01 12.93 50.00
195 INT43820 Positive_regulation of Twist1 75 0.59 42.15 8.47 50.00
196 INT49805 Positive_regulation of MUC1 56 0.70 44.5 4.56 50.00
197 INT145270 Gene_expression of ABCG2 19 0.75 7.87 2.69 50.00
198 INT9473 Binding of MUC1 66 0.48 46.77 2.36 50.00
199 INT10873 Localization of Twist1 21 0.74 10.43 1.37 50.00
200 INT66491 Regulation of CES2 2 0.45 1.51 0.86 50.00
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