D:Snake Bites

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Disease Term
Synonyms BITE SNAKE, BITES SNAKE, Envenomation Snake, Envenomations Snake, SNAKE BITE, SNAKE ENVENOMATION, SNAKE ENVENOMATIONS
Documents 119
Hot Single Events 8
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Snake Bites. They are ordered first by their relevance to Snake Bites and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT308120 Binding of F2 and F10 2 0.07 1.25 0.25 53.20
2 INT298472 LPA Positive_regulation of Gene_expression of CXCL16 1 0.05 0.41 0.32 5.00
3 INT350214 Binding of GPER and HSPG2 1 0.00 0.12 0.32 5.00
4 INT298501 Paf Regulation of Negative_regulation of Alms1 1 0.00 0.63 0.29 5.00
5 INT101810 Binding of NFE2L2 and KEAP1 7 0.53 4.12 0.29 5.00
6 INT326404 Binding of Cck and Enpep 1 0.01 0.19 0.23 5.00
7 INT298475 LPA Positive_regulation of Gene_expression of IL8 1 0.07 0.38 0.15 5.00
8 INT298500 Alb Positive_regulation of Paf 1 0.01 0.34 0.15 5.00
9 INT298476 CD40LG Positive_regulation of HLA-DRB1 1 0.01 0.33 0.12 5.00
10 INT298471 CD40LG Positive_regulation of CD80 1 0.04 0.33 0.12 5.00
11 INT298479 CD40LG Positive_regulation of CD40LG Positive_regulation of HLA-DRB1 1 0.00 0.33 0.12 5.00
12 INT298474 IL4 Positive_regulation of HLA-DRB1 1 0.02 0.33 0.12 5.00
13 INT298478 IL4 Positive_regulation of CD40LG Positive_regulation of HLA-DRB1 1 0.01 0.33 0.12 5.00
14 INT298473 IL4 Positive_regulation of CD80 1 0.06 0.33 0.12 5.00
15 INT298497 CTSC Positive_regulation of F10 Positive_regulation of F2 1 0.00 0.12 0.1 5.00
16 INT350220 Positive_regulation of HSPG2 Positive_regulation of Localization of ITPR3 1 0.05 0.09 0.09 5.00
17 INT350216 ITPR3 Regulation of Localization of TNIP3 1 0.01 0.08 0.09 5.00
18 INT298502 F10 Positive_regulation of F2 1 0.00 0.12 0.09 5.00
19 INT350217 Positive_regulation of HSPG2 Positive_regulation of ITPR3 1 0.05 0.09 0.09 5.00
20 INT350218 Positive_regulation of HSPG2 Positive_regulation of Gene_expression of ITPR3 1 0.04 0.09 0.08 5.00
21 INT350219 ITPR3 Positive_regulation of CA2 1 0.22 0 0.05 5.00
22 INT246061 KEAP1 Regulation of Positive_regulation of NFE2L2 1 0.34 0 0 5.00
23 INT246058 Binding of KEAP1 and Positive_regulation of NFE2L2 1 0.38 0 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Snake Bites. They are ordered first by their pain relevance and then by number of times they were reported in Snake Bites. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT7134 Localization of KNG1 127 0.79 65.73 67.97 98.84
2 INT7678 Localization of Alb 142 0.81 80.93 22.49 97.88
3 INT114715 Binding of SRC 8 0.36 4.26 1.32 95.28
4 INT53948 Regulation of Gene_expression of Cpox 40 0.51 20.97 13.87 91.00
5 INT51921 Gene_expression of Cpox 501 0.73 229.81 157.81 90.60
6 INT81934 Gene_expression of Il4i1 4 0.22 1.91 0.65 86.60
7 INT4435 Gene_expression of PIK3C2A 20 0.77 14.43 2.48 83.60
8 INT33579 Positive_regulation of Enpep 4 0.33 5.09 0.58 82.08
9 INT711 Positive_regulation of PIK3C2A 83 0.70 76.87 13.18 77.84
10 INT2129 Positive_regulation of F2 83 0.70 58.95 12.63 68.72
11 INT9852 Positive_regulation of Gpt 563 0.70 364.64 146.82 61.04
12 INT196322 Binding of F2 18 0.15 7.74 0.83 55.28
13 INT172479 Positive_regulation of NFE2L2 74 0.70 35.22 0.79 55.12
14 INT66762 Negative_regulation of Pla2g10 6 0.48 7.8 4.54 54.48
15 INT17565 Regulation of Gpt 85 0.60 43.64 13.68 53.96
16 INT320172 Negative_regulation of Binding of F2 2 0.41 1.92 0.5 53.72
17 INT83601 Binding of CNR2 30 0.47 7.79 12.37 53.56
18 INT69980 Negative_regulation of Il1rn 11 0.33 7.75 6.7 53.48
19 INT69310 Negative_regulation of IL1A 10 0.43 7.83 5.05 53.48
20 INT9842 Binding of F2 36 0.47 22.79 4.42 53.20
21 INT82845 Binding of F10 25 0.37 7.07 0.81 52.00
22 INT82610 Positive_regulation of SRC 53 0.67 26.89 7.27 50.00
23 INT36263 Positive_regulation of CEL 53 0.69 34.88 12.87 49.56
24 INT50740 Positive_regulation of SPG21 18 0.67 8.3 1.65 49.56
25 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98 48.88
26 INT81495 Positive_regulation of CNR2 28 0.67 14.62 14.27 42.08
27 INT9647 Gene_expression of PROC 163 0.65 89.76 26.75 37.60
28 INT15613 Negative_regulation of Ptgs2 160 0.59 71.08 65.08 32.24
29 INT3332 Protein_catabolism of AGT 23 0.87 3.17 4.39 31.92
30 INT73595 Positive_regulation of BAX 61 0.61 56.97 7.82 30.80
31 INT238507 Regulation of Regulation of BCL2 3 0.44 5.14 0.16 30.68
32 INT297776 Protein_catabolism of Enpep 3 0.41 4.62 0.36 30.32
33 INT197568 Regulation of NFE2L2 17 0.59 7.85 0.15 29.84
34 INT84685 Regulation of BCL2 67 0.60 72.96 6.65 29.60
35 INT1495 Positive_regulation of Rtcd1 91 0.54 22.93 32.43 25.00
36 INT38807 Negative_regulation of PLA2G6 29 0.59 10.1 6.42 16.16
37 INT161326 Binding of C4BPB 3 0.35 2.58 0.69 12.20
38 INT899 Gene_expression of F13A1 122 0.70 78.02 16.26 8.76
39 INT116229 Gene_expression of C1qa 28 0.77 18.53 5.35 5.44
40 INT4585 Gene_expression of Serping1 19 0.46 12.4 2.35 5.44
41 INT201570 Gene_expression of CR2 11 0.48 14.21 0.22 5.44
42 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 5.00
43 INT10832 Gene_expression of IL8 1050 0.78 698.72 270 5.00
44 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97 5.00
45 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 5.00
46 INT120811 Gene_expression of Gopc 1174 0.59 428.49 150.55 5.00
47 INT69440 Gene_expression of ROS1 752 0.78 477.64 103.83 5.00
48 INT10838 Positive_regulation of IL8 381 0.70 295.51 101.62 5.00
49 INT11587 Gene_expression of CSF2 645 0.78 544.38 93.89 5.00
50 INT86024 Gene_expression of PPARA 736 0.78 497.93 91.14 5.00
51 INT62374 Gene_expression of NGF 158 0.78 77.87 76.45 5.00
52 INT10837 Positive_regulation of Gene_expression of IL8 294 0.70 190.08 70.34 5.00
53 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73 5.00
54 INT6849 Localization of IL1B 229 0.81 112.56 69.63 5.00
55 INT4960 Positive_regulation of CSF2 285 0.70 256.73 65.73 5.00
56 INT822 Gene_expression of ESR1 529 0.78 302.16 63.64 5.00
57 INT67614 Positive_regulation of PPARA 438 0.68 293.28 63.61 5.00
58 INT55344 Gene_expression of Ros1 396 0.54 217.64 59.98 5.00
59 INT169926 Positive_regulation of Gopc 416 0.46 157.8 58.67 5.00
60 INT6979 Positive_regulation of CA2 206 0.67 50.79 44.97 5.00
61 INT4216 Gene_expression of CD40LG 328 0.78 256.02 44.23 5.00
62 INT69437 Positive_regulation of ROS1 328 0.58 222.83 40.56 5.00
63 INT16194 Binding of CNR1 82 0.48 20.75 39.59 5.00
64 INT63349 Gene_expression of PECAM1 199 0.75 166.03 36.76 5.00
65 INT12892 Negative_regulation of TIMP1 136 0.58 83.13 36.54 5.00
66 INT103094 Binding of PPARA 308 0.47 177.26 34.75 5.00
67 INT5489 Localization of CA2 172 0.80 39.46 33.56 5.00
68 INT9796 Gene_expression of Cck 63 0.78 11.44 32.09 5.00
69 INT99688 Negative_regulation of Gene_expression of VEGFA 274 0.58 201.8 31.1 5.00
70 INT9650 Gene_expression of LPA 141 0.75 104.57 29 5.00
71 INT28361 Gene_expression of TP53 443 0.78 384.86 28.8 5.00
72 INT16814 Negative_regulation of COX5A 74 0.57 33.72 28.63 5.00
73 INT9296 Negative_regulation of PLEK 100 0.57 36.65 27.52 5.00
74 INT15089 Regulation of SLC6A4 48 0.62 17.87 25.6 5.00
75 INT81496 Gene_expression of CNR2 68 0.75 30.04 24.92 5.00
76 INT172458 Regulation of Gopc 155 0.53 62.57 24.86 5.00
77 INT49196 Gene_expression of SELE 105 0.78 107.29 22.92 5.00
78 INT3330 Gene_expression of AGT 149 0.76 98.65 22.73 5.00
79 INT823 Negative_regulation of ESR1 144 0.58 63.72 22.52 5.00
80 INT35711 Positive_regulation of Sdcbp 110 0.60 50.45 22.11 5.00
81 INT101517 Negative_regulation of PPARA 168 0.57 112.24 21.41 5.00
82 INT5328 Positive_regulation of CD4 191 0.69 133.43 21.31 5.00
83 INT72060 Positive_regulation of Gene_expression of Ros1 127 0.41 76.76 20.91 5.00
84 INT170444 Binding of Gopc 172 0.39 45.05 20.71 5.00
85 INT1756 Negative_regulation of DNAH8 105 0.59 42.73 20.24 5.00
86 INT23533 Gene_expression of CA2 110 0.75 30.81 19.4 5.00
87 INT1060 Negative_regulation of Pla2g1b 50 0.57 22.91 18.12 5.00
88 INT9246 Positive_regulation of Cat 113 0.70 52.73 18.04 5.00
89 INT170051 Positive_regulation of Gene_expression of Gopc 150 0.43 56.75 16.93 5.00
90 INT17313 Positive_regulation of HSPG2 57 0.67 55.78 16.65 5.00
91 INT11685 Regulation of CSF2 99 0.59 58.82 15.9 5.00
92 INT13400 Negative_regulation of Enpep 30 0.50 4.23 15.86 5.00
93 INT92354 Localization of ESR1 77 0.75 33.04 15.51 5.00
94 INT25493 Gene_expression of TFPI 74 0.76 39.44 14.78 5.00
95 INT100139 Positive_regulation of Gene_expression of PPARA 160 0.63 97.78 14.53 5.00
96 INT1982 Regulation of NARFL 119 0.49 116.2 14.35 5.00
97 INT35120 Gene_expression of Sdcbp 68 0.67 21.33 13.96 5.00
98 INT36177 Binding of Alms1 70 0.31 35.47 13.81 5.00
99 INT5207 Negative_regulation of Alms1 70 0.41 41.56 13.68 5.00
100 INT22213 Localization of Gpt 52 0.78 34.05 12.94 5.00
101 INT62441 Gene_expression of ABCC1 56 0.78 21.01 12.93 5.00
102 INT116528 Gene_expression of HMOX1 106 0.78 86.13 12.8 5.00
103 INT8232 Gene_expression of Paf 21 0.67 22.18 12.8 5.00
104 INT12135 Gene_expression of PLEK 62 0.75 34.13 12.47 5.00
105 INT11793 Negative_regulation of CA2 78 0.57 19.63 12.35 5.00
106 INT55687 Localization of TIMP1 47 0.74 30.24 12.31 5.00
107 INT69436 Negative_regulation of Gene_expression of ROS1 81 0.38 46.58 12.22 5.00
108 INT112003 Localization of ROS1 94 0.73 66.32 12.16 5.00
109 INT2415 Binding of MAOA 26 0.47 13.26 11.86 5.00
110 INT28872 Positive_regulation of CSRP1 49 0.70 47.23 11.7 5.00
111 INT49142 Gene_expression of SELP 94 0.75 54.61 11.64 5.00
112 INT24816 Binding of CD40LG 68 0.47 45.48 11.56 5.00
113 INT13303 Positive_regulation of PTAFR 40 0.69 16.27 11.56 5.00
114 INT111223 Positive_regulation of HMOX1 47 0.70 39.14 10.92 5.00
115 INT3535 Regulation of CA2 61 0.32 16.48 10.8 5.00
116 INT18412 Binding of PLEK 49 0.47 17.82 10.72 5.00
117 INT150540 Binding of TLR2 50 0.45 35.86 10.43 5.00
118 INT94784 Binding of ROS1 113 0.40 71.57 10.26 5.00
119 INT122584 Negative_regulation of Gene_expression of PPARA 56 0.58 37.61 9.76 5.00
120 INT178306 Negative_regulation of Gene_expression of Gopc 71 0.37 26.43 9.74 5.00
121 INT47390 Negative_regulation of Paf 18 0.58 14.81 9.66 5.00
122 INT23535 Positive_regulation of Localization of CA2 41 0.41 13.52 9.43 5.00
123 INT30526 Negative_regulation of PTAFR 15 0.58 8.15 8.19 5.00
124 INT57748 Positive_regulation of Gene_expression of TP53 85 0.69 79.55 7.49 5.00
125 INT1123 Positive_regulation of CD79A 74 0.70 51.96 7.14 5.00
126 INT75382 Negative_regulation of HSPG2 20 0.57 15.18 7.03 5.00
127 INT11957 Negative_regulation of LPA 52 0.59 39.09 6.84 5.00
128 INT39516 Gene_expression of Alb 81 0.75 30.08 6.59 5.00
129 INT37745 Positive_regulation of Gene_expression of Sdcbp 22 0.60 5.15 6.02 5.00
130 INT254400 Negative_regulation of GSN 22 0.57 18.15 5.89 5.00
131 INT18677 Gene_expression of F3 50 0.65 30.86 5.86 5.00
132 INT26919 Gene_expression of ITPR3 47 0.42 5.86 5.79 5.00
133 INT3731 Negative_regulation of Neu1 17 0.39 8.35 5.67 5.00
134 INT5490 Binding of CA2 52 0.36 9.73 5.53 5.00
135 INT45753 Localization of CD40LG 45 0.79 32.31 5.28 5.00
136 INT26334 Localization of ITPR3 39 0.49 2.53 5.07 5.00
137 INT11030 Binding of LPA 70 0.48 40.35 4.81 5.00
138 INT82354 Positive_regulation of PECAM1 25 0.34 22.93 4.69 5.00
139 INT107605 Gene_expression of MMP14 26 0.64 25.88 4.49 5.00
140 INT35122 Negative_regulation of Sdcbp 43 0.51 22.01 4.34 5.00
141 INT57645 Gene_expression of GSTK1 54 0.62 21.05 4.2 5.00
142 INT133312 Binding of MMP9 25 0.42 16.79 3.83 5.00
143 INT47391 Positive_regulation of Paf 16 0.62 12.31 3.79 5.00
144 INT13302 Binding of PTAFR 20 0.48 7.03 3.7 5.00
145 INT10053 Localization of Paf 15 0.80 9.14 3.64 5.00
146 INT9854 Localization of GGT1 11 0.78 6.09 3.57 5.00
147 INT6405 Gene_expression of Enpep 9 0.67 4.79 3.4 5.00
148 INT120874 Regulation of CNR2 7 0.44 2.47 3.39 5.00
149 INT43985 Regulation of LPA 29 0.62 20.79 3.29 5.00
150 INT95723 Localization of TNIP3 6 0.03 0.71 3.21 5.00
151 INT140555 Positive_regulation of Localization of ROS1 29 0.55 23.82 3.14 5.00
152 INT91520 Negative_regulation of Positive_regulation of CA2 7 0.30 0.99 2.92 5.00
153 INT597 Positive_regulation of PON1 26 0.62 19.14 2.87 5.00
154 INT68576 Positive_regulation of Positive_regulation of CSF2 8 0.40 8.1 2.83 5.00
155 INT123910 Gene_expression of CXCL16 5 0.49 3.81 2.82 5.00
156 INT61075 Gene_expression of PMP2 23 0.61 7.42 2.79 5.00
157 INT222961 Negative_regulation of Binding of PPARA 22 0.41 10.76 2.72 5.00
158 INT93562 Negative_regulation of Localization of CA2 15 0.59 1.87 2.51 5.00
159 INT26918 Positive_regulation of Gene_expression of ITPR3 14 0.27 2.31 2.41 5.00
160 INT59362 Binding of PMP2 22 0.38 4.26 2.29 5.00
161 INT100886 Gene_expression of GCLC 16 0.76 5.63 2.29 5.00
162 INT65459 Binding of Racgap1 9 0.07 4.57 2.28 5.00
163 INT23588 Positive_regulation of CCR1 6 0.67 4.44 2.24 5.00
164 INT92129 Positive_regulation of Gene_expression of F3 13 0.08 12.13 2.02 5.00
165 INT33845 Binding of GPER 20 0.36 5.61 1.81 5.00
166 INT51896 Localization of PECAM1 11 0.47 9.8 1.78 5.00
167 INT8556 Positive_regulation of NQO1 12 0.70 5.11 1.78 5.00
168 INT48357 Positive_regulation of Anpep 7 0.39 2.04 1.75 5.00
169 INT24283 Regulation of Positive_regulation of CA2 8 0.30 3.06 1.74 5.00
170 INT9648 Positive_regulation of Gene_expression of LPA 15 0.59 11.31 1.72 5.00
171 INT64807 Positive_regulation of Positive_regulation of CA2 10 0.41 1.21 1.7 5.00
172 INT101816 Localization of NFE2L2 17 0.77 6.91 1.69 5.00
173 INT120505 Negative_regulation of ITPR3 6 0.27 1.46 1.68 5.00
174 INT117330 Negative_regulation of Binding of ROS1 13 0.37 8.33 1.67 5.00
175 INT17693 Localization of PF4 2 0.68 1.26 1.56 5.00
176 INT168682 Localization of NDRG1 3 0.36 0.84 1.45 5.00
177 INT26772 Regulation of CPQ 5 0.45 0.18 1.35 5.00
178 INT138013 Binding of Paf 5 0.47 3.71 1.31 5.00
179 INT23308 Gene_expression of CPQ 12 0.71 0.54 1.3 5.00
180 INT291800 Positive_regulation of NEU2 2 0.01 0.57 1.26 5.00
181 INT46336 Regulation of DNMT3B 12 0.53 4.91 1.25 5.00
182 INT70327 Regulation of Gene_expression of CA2 11 0.28 1.92 1.05 5.00
183 INT185501 Localization of NEU2 4 0.02 1.08 1.04 5.00
184 INT105445 Localization of HMOX1 5 0.71 3.11 0.98 5.00
185 INT71906 Regulation of Gene_expression of ESR1 22 0.41 11.01 0.98 5.00
186 INT147113 Binding of LTF 14 0.29 18.24 0.98 5.00
187 INT58107 Negative_regulation of MPG 2 0.41 0.92 0.98 5.00
188 INT298493 Localization of TREML1 1 0.13 1.43 0.95 5.00
189 INT224007 Positive_regulation of PMP2 6 0.40 3.46 0.94 5.00
190 INT264171 Positive_regulation of Positive_regulation of CD4 5 0.49 4.74 0.94 5.00
191 INT269601 Positive_regulation of TNIP3 7 0.02 0.64 0.9 5.00
192 INT114769 Regulation of Enpep 6 0.14 0.58 0.89 5.00
193 INT47490 Regulation of Positive_regulation of CSF2 2 0.39 1.42 0.88 5.00
194 INT190363 Positive_regulation of Negative_regulation of PPARA 10 0.44 4.8 0.87 5.00
195 INT71608 Regulation of Positive_regulation of Paf 1 0.35 1.04 0.83 5.00
196 INT151815 Localization of RUNX1 3 0.68 1.87 0.81 5.00
197 INT230493 Regulation of Binding of Alms1 3 0.12 1.89 0.76 5.00
198 INT102813 Regulation of Gene_expression of TP53 25 0.59 25.95 0.75 5.00
199 INT72123 Positive_regulation of Negative_regulation of Paf 3 0.53 1.04 0.69 5.00
200 INT26333 Positive_regulation of Localization of ITPR3 6 0.43 0.17 0.68 5.00
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